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Management of acute sexual assault presenting to a large Australian sexual health clinic in 2012–2021: a retrospective clinical audit 2012-2021 年澳大利亚一家大型性健康诊所对急性性侵犯患者的管理:回顾性临床审计
IF 1.6 4区 医学 Q3 INFECTIOUS DISEASES Pub Date : 2024-04-11 DOI: 10.1071/sh23175
Aleah Kink, Janet M. Towns, Christopher K. Fairley, Tiffany R. Phillips, Catriona S. Bradshaw, Eric P. F. Chow
Background

The incidence of sexual assault continues to rise in Australia. This study aimed to describe the nature of assault, HIV/STI positivity, and its management at a sexual health clinic.

Methods

We performed a chart review of 516 sexual assault cases presenting to Melbourne Sexual Health Centre between 2012 and 2021, collecting data on victim demographics, details of assault, HIV/STI testing and positivity, police involvement, and offer of counselling.

Results

We included 516 cases: 124 males (24.0%); 384 females (74.4%); and eight transgender (1.6%) victims. The proportion of assault cases presenting to Melbourne Sexual Health Centre increased from 0.1% (37/37,070) in 2012 to 0.2% (56/36,514) in 2021 (Ptrend = 0.006). HIV post-exposure prophylaxis was prescribed for 64.5% (80/124) of males and 12.5% (48/384) of females. Among victims, 69.4% (358/516) were tested for HIV and no one tested positive, while 71.9% (371/516) were tested for syphilis, with 1.6% (6/371) positive. Gonorrhoea and chlamydia were tested at the oropharynx (44.8% [231/516] vs 28.7% [148/516]), genitals (83.7% [432/516] vs 92.4% [477/516]) and anorectum (35.3% [182/516] vs 35.3% [182/516]). Positivity for gonorrhoea and chlamydia were: 2.6% (6/231) vs 2.0% (3/148) at oropharynx, 1.4% (6/432) vs 2.9% (14/477) at genitals, and 5.5% (10/182) vs 7.1% (13/182) at anorectum. According to clinical records, 25.2% (130/516) of victims sought police involvement, and 71.7% (370/516) were offered counselling.

Conclusions

Sexual assault was an uncommon presentation at Melbourne Sexual Health Centre, with diverse circumstances surrounding assault; however, clinical documentation varied, indicating a need for a standard primary care protocol for clients presenting with acute sexual assault.

背景澳大利亚的性侵犯发生率持续上升。本研究旨在描述性侵犯的性质、HIV/STI 阳性率以及性健康诊所的处理方法。方法我们对 2012 年至 2021 年间墨尔本性健康中心接诊的 516 例性侵犯病例进行了病历回顾,收集了受害者人口统计学、侵犯细节、HIV/STI 检测和阳性、警方介入以及提供咨询等方面的数据。结果我们纳入了 516 个病例:其中包括 124 名男性(24.0%)、384 名女性(74.4%)和 8 名变性人(1.6%)。到墨尔本性健康中心就诊的袭击案件比例从2012年的0.1%(37/37,070)上升到2021年的0.2%(56/36,514)(Ptrend = 0.006)。64.5%的男性(80/124)和12.5%的女性(48/384)接受了艾滋病毒暴露后预防治疗。在受害者中,69.4%(358/516)接受了艾滋病毒检测,无人呈阳性;71.9%(371/516)接受了梅毒检测,1.6%(6/371)呈阳性。淋病和衣原体的检测部位包括口咽(44.8% [231/516] vs 28.7% [148/516])、生殖器(83.7% [432/516] vs 92.4% [477/516])和肛门直肠(35.3% [182/516] vs 35.3% [182/516])。淋病和衣原体阳性率分别为口咽部 2.6% (6/231) vs 2.0% (3/148),生殖器 1.4% (6/432) vs 2.9% (14/477),肛门直肠 5.5% (10/182) vs 7.1% (13/182)。根据临床记录,25.2%(130/516)的受害者寻求警方介入,71.7%(370/516)的受害者获得了心理辅导。结论在墨尔本性健康中心,性侵犯是一种不常见的病症,围绕性侵犯的情况多种多样;然而,临床记录却各不相同,这表明需要为急性性侵犯患者制定标准的初级保健方案。
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引用次数: 0
Catching lightning in a bottle: the STI and HIV 2023 World Congress Participatory Designathon. 瓶中捉雷:2023 年性传播感染和艾滋病世界大会参与式设计马拉松。
IF 1.6 4区 医学 Q3 INFECTIOUS DISEASES Pub Date : 2024-03-01 DOI: 10.1071/SH23205
Ronnie M Gravett, Rayner K J Tan, Weiming Tang, Steph Niapauri, Barbara Van Der Pol, Joseph D Tucker

The International Society for STD Research (ISSTDR) STI/HIV 2023 World Congress convened a participatory designathon to engage attendees in a problem-solving crowdsourcing event with the mission to design innovative solutions for improving sexually transmitted infection (STI) control. Designathons are three-phase crowdsourcing events consisting of a pre-planning phase, an active and intensive collaborative phase, and denouement phase for implementation and dissemination. Given escalating STI concerns, the Congress organisers recognised the opportunity to harness the collective expertise of the attendees by actively engaging them to generate innovative solutions for STI control by hosting a designathon during the scientific meeting. Designathon activities occurred during the Congress, and innovative solutions were presented during the closing plenary. Organisers prioritised participant diversity and engagement by creating four distinct groups based on lived experiences (Silver, Early Career, Traveller, and Community). Although competing priorities through the Congress were a challenge, participation from the attendees was high. Dedicated time and space for the event allowed for a successful designathon event, and the lack of restrictions, as might be encountered from funders or other stakeholder agencies, allowed participants to creatively develop innovative solutions for STI control. This designathon serves as an exemplar for successfully hosting a designathon at a large scientific meeting to engage attendees and contribute their intellect and voice to collectively solving significant problems.

国际性传播疾病研究学会(ISSTDR)2023 年性传播疾病/艾滋病毒世界大会举办了一次参与式设计马拉松活动,让与会者参与到解决问题的众包活动中来,目的是为改善性传播疾病(STI)控制设计创新解决方案。设计马拉松是三阶段的众包活动,包括前期规划阶段、积极深入的合作阶段以及实施和传播的结束阶段。鉴于人们对性传播感染的关注不断升级,大会组织者意识到有机会利用与会者的集体专长,通过在科学会议期间举办设计马拉松活动,让与会者积极参与进来,为性传播感染控制提出创新解决方案。大会期间开展了设计马拉松活动,并在闭幕全体会议上介绍了创新解决方案。组织者将与会者的多样性和参与性放在首位,根据生活经验设立了四个不同的小组(银发族、早期职业者、旅行者和社区)。虽然大会期间的优先事项相互竞争是一项挑战,但与会者的参与度很高。专门的时间和空间使设计马拉松活动取得了成功,而且由于没有资金提供者或其他利益相关机构的限制,与会者能够创造性地开发出创新的科技创新控制解决方案。这次设计马拉松活动是在大型科学会议上成功举办设计马拉松活动的典范,可以让与会者参与进来,为共同解决重大问题贡献自己的智慧和声音。
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引用次数: 0
Acceptance and use of condoms among school-aged young people in Australia. 澳大利亚学龄青少年对安全套的接受和使用情况。
IF 1.6 4区 医学 Q3 INFECTIOUS DISEASES Pub Date : 2024-03-01 DOI: 10.1071/SH23173
Jennifer Power, Sylvia Kauer, Christopher Fisher, Adam Bourne

Background: Despite availability of vaccines or medical prophylaxis for some sexually transmissible infections (STIs), promoting condom use remains an important public health strategy for the prevention of STIs. Recent research shows that regular condom use among young people in Australia has declined over the past decade, while the rate of common STIs has increased.

Method: In this paper, we report findings from a large survey of school-aged young people in Australia (14-18years old) in which we looked at the association between condom use and positive feelings about sex, beliefs about social acceptability of condoms and confidence talking with partners about sex and condoms.

Results: Communication and relational factors supported more consistent condom use. Participants were more likely to regularly use condoms if they discussed condom use with a sexual partner, perceived condom use to be easy (a measure that included perceived ease of discussing condoms with a partner) and perceived condom use to offer social or relational benefits, including perceiving condom use as a demonstration of care for a partner. Young men were more likely to report positive feelings about sex and regular condom use than young women. Young women were less likely than young men or trans and non-binary young people to report regular condom use.

Conclusions: The study shows the importance of supporting young people to build confidence expressing sexual needs and wants with partners. Public health approaches to STI prevention need to consider condom promotion in the context of young people's contemporary sexual, gendered and relationships cultures.

背景:尽管某些性传播感染(STI)可以通过疫苗或药物预防,但推广使用安全套仍然是预防性传播感染的一项重要公共卫生策略。最近的研究表明,在过去十年中,澳大利亚年轻人定期使用安全套的比例有所下降,而常见性传播疾病的发病率却有所上升:在本文中,我们报告了一项针对澳大利亚学龄青少年(14-18 岁)的大型调查的结果,其中我们研究了安全套的使用与对性的积极感受、对安全套的社会接受度的信念以及与伴侣谈论性和安全套的信心之间的关系:结果:交流和关系因素支持更持续地使用安全套。如果参与者与性伴侣讨论过使用安全套的问题,认为使用安全套很容易(这一指标包括与伴侣讨论安全套问题的难易程度),并认为使用安全套能带来社会或关系方面的好处,包括认为使用安全套是关心伴侣的表现,那么他们就更有可能定期使用安全套。与年轻女性相比,年轻男性更倾向于报告对性和定期使用安全套的积极感受。与年轻男性或变性和非二元青年相比,年轻女性不太可能报告经常使用安全套:这项研究表明,支持年轻人建立自信,与伴侣一起表达性需求和愿望非常重要。预防性传播疾病的公共卫生方法需要结合年轻人的当代性文化、性别文化和人际关系文化来考虑安全套的推广。
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引用次数: 0
'Every strategy needs to be contributing to erasing the stigma': Māori and Pacific young people talk about overcoming barriers to testing for sexually transmitted infections. 每项战略都应有助于消除污名化":毛利族和太平洋岛屿族裔的年轻人谈论如何克服性传播感染检测方面的障碍。
IF 1.6 4区 医学 Q3 INFECTIOUS DISEASES Pub Date : 2024-03-01 DOI: 10.1071/SH23186
Sally B Rose, Abby Dunlop, Tracey Gardiner, Marama Cole, Susan M Garrett, Eileen M McKinlay

Background: Māori and Pacific young people are disproportionately impacted by sexually transmitted infections (STIs). Access to STI screening is important to reduce transmission and reproductive health complications.

Methods: Between November 2022 and May 2023, we held four wānanga (workshops) with Māori and Pacific participants (15-24years old) to find out what barriers they encounter to STI testing, and hear their ideas about how to overcome these. Participants were recruited via youth-focused community organisations in the Wellington region of Aotearoa New Zealand. Inductive thematic analysis was used to understand data generated from discussions, drawing on Māori and Pacific models of wellbeing to frame themes.

Results: Thirty-eight participants were involved in the wānanga. Barriers to STI testing related to five themes: (1) differences in cultural values and expression; (2) family/friends; (3) educational gaps; (4) psychological factors; and (5) structural obstacles. Suggested strategies to improve access to sexual health care included the need for free, flexible services, education and health promotion activities to reach young people in their spaces (e.g. church, marae, social media). Participants stressed the need for approaches to be community-based, delivered by trusted individuals using culturally appropriate messages, and saw participation in STI testing as beneficial for whānau/family and communities.

Conclusions: To improve access to STI testing, participants described the need for free services, together with education and health promotion to improve inter-generational sexual health knowledge. Reframing messages around STIs to align with Māori and Pacific models of wellbeing was identified as a way to normalise conversations, in turn reducing the stigma surrounding STI testing.

背景介绍毛利人和太平洋裔年轻人受到性传播感染(STI)的影响尤为严重。接受性传播感染筛查对于减少传播和生殖健康并发症非常重要:2022 年 11 月至 2023 年 5 月期间,我们与毛利人和太平洋裔参与者(15-24 岁)举办了四次研讨会(wānanga),以了解他们在性传播感染检测方面遇到了哪些障碍,并听取他们关于如何克服这些障碍的想法。参与者是通过新西兰奥特亚罗瓦惠灵顿地区以青年为重点的社区组织招募的。我们采用归纳主题分析法来理解讨论中产生的数据,并借鉴毛利人和太平洋地区的幸福模式来确定主题:结果:38 名参与者参与了 wānanga。性传播感染检测的障碍涉及五个主题:(1) 文化价值观和表达方式的差异;(2) 家庭/朋友;(3) 教育差距;(4) 心理因素;(5) 结构性障碍。所建议的改善性健康保健的战略包括需要提供免费、灵活的服务、教育和健康宣传活动,以便在年轻人的空间(如教堂、marae、社交媒体)接触到他们。与会者强调,这些方法必须以社区为基础,由可信赖的个人利用文化上适当的信息来提供,并认为参与性传播感染检测对家庭和社区都有好处:结论:为改善性传播感染检测的可及性,参与者认为有必要提供免费服务,同时开展教育和健康宣传,以提高各代人的性健康知识。与会者认为,重塑有关性传播感染的信息,使其与毛利人和太平洋地区的健康模式相一致,是使对话正常化的一种方式,从而减少围绕性传播感染检测的污名化。
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引用次数: 0
Characterisation of social media conversations on syphilis: an unobtrusive observational study. 梅毒社交媒体对话的特点:一项非侵入性观察研究。
IF 1.6 4区 医学 Q3 INFECTIOUS DISEASES Pub Date : 2024-03-01 DOI: 10.1071/SH23114
Abby C Dawson, Alyssa K Fitzpatrick, Janet M Matthews, Andrew A K Nguyen, Kelly Papanaoum, Justine R Smith

Background: Conversations around disease conducted through social media provide a means for capturing public perspectives that may be useful in considering public health approaches. Syphilis is a sexually transmitted disease that is re-emerging. We sought to characterise online discourse on syphilis using data collected from the social media platform, Twitter.

Methods: We extracted English-language tweets containing the word 'syphilis' posted on Twitter in 2019. Tweet identification number and URL, date and time of posting, number of retweets and likes, and the author's screen name, username and biographical statement were included in the dataset. A systematically sampled 10% subset of the data was subjected to qualitative analysis, involving categorisation on content. All tweets assigned to the category of medical resource were assessed for clinical accuracy. The engagement ratio for each category was calculated as (retweets+likes):tweets.

Results: In 2019, 111,388 tweets mentioning syphilis were posted by 69,921 authors. The most frequent content category - totalling 5370 tweets (48%) - was a joke. Of 1762 tweets (16%) categorised as a medical resource, 1484 (84%) were medically correct and 240 (14%) were medically incorrect; for 38 (2%), medical accuracy could not be judged from the information posted. Tweets categorised as personal experiences had the highest engagement ratio at approximately 19:1. Medical resource tweets had an engagement ratio of approximately 7:1.

Conclusions: We found medical information about syphilis was limited on Twitter. As tweets about personal experiences generate high engagement, coupling an experience with information may provide opportunity for public health education.

背景:通过社交媒体围绕疾病开展的对话提供了一种捕捉公众观点的手段,这可能有助于考虑公共卫生方法。梅毒是一种正在重新出现的性传播疾病。我们试图利用从社交媒体平台推特(Twitter)上收集到的数据来描述有关梅毒的网络讨论的特点:我们提取了 2019 年在 Twitter 上发布的包含 "梅毒 "一词的英文推文。数据集包括推文标识号和 URL、发布日期和时间、转发和点赞数以及作者的网名、用户名和履历声明。对系统抽取的 10% 数据子集进行了定性分析,包括内容分类。所有归入医疗资源类别的推文都经过了临床准确性评估。每个类别的参与比例按(转发+赞):推文计算:2019年,69,921位作者发布了111,388条提及梅毒的推文。最常见的内容类别是笑话,共有5370条推文(占48%)。在 1762 条(16%)被归类为医疗资源的推文中,1484 条(84%)在医学上是正确的,240 条(14%)在医学上是错误的;38 条(2%)无法从发布的信息中判断医学准确性。归类为个人经历的推文参与度最高,约为 19:1。医疗资源推文的参与比例约为 7:1:我们发现推特上有关梅毒的医疗信息非常有限。由于有关个人经历的推文产生了较高的参与度,因此将个人经历与信息相结合可能会为公共卫生教育提供机会。
{"title":"Characterisation of social media conversations on syphilis: an unobtrusive observational study.","authors":"Abby C Dawson, Alyssa K Fitzpatrick, Janet M Matthews, Andrew A K Nguyen, Kelly Papanaoum, Justine R Smith","doi":"10.1071/SH23114","DOIUrl":"10.1071/SH23114","url":null,"abstract":"<p><strong>Background: </strong>Conversations around disease conducted through social media provide a means for capturing public perspectives that may be useful in considering public health approaches. Syphilis is a sexually transmitted disease that is re-emerging. We sought to characterise online discourse on syphilis using data collected from the social media platform, Twitter.</p><p><strong>Methods: </strong>We extracted English-language tweets containing the word 'syphilis' posted on Twitter in 2019. Tweet identification number and URL, date and time of posting, number of retweets and likes, and the author's screen name, username and biographical statement were included in the dataset. A systematically sampled 10% subset of the data was subjected to qualitative analysis, involving categorisation on content. All tweets assigned to the category of medical resource were assessed for clinical accuracy. The engagement ratio for each category was calculated as (retweets+likes):tweets.</p><p><strong>Results: </strong>In 2019, 111,388 tweets mentioning syphilis were posted by 69,921 authors. The most frequent content category - totalling 5370 tweets (48%) - was a joke. Of 1762 tweets (16%) categorised as a medical resource, 1484 (84%) were medically correct and 240 (14%) were medically incorrect; for 38 (2%), medical accuracy could not be judged from the information posted. Tweets categorised as personal experiences had the highest engagement ratio at approximately 19:1. Medical resource tweets had an engagement ratio of approximately 7:1.</p><p><strong>Conclusions: </strong>We found medical information about syphilis was limited on Twitter. As tweets about personal experiences generate high engagement, coupling an experience with information may provide opportunity for public health education.</p>","PeriodicalId":22165,"journal":{"name":"Sexual health","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140207589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Barriers to engagement with testing for sexually transmitted infections within a UK-based young adult Black Caribbean community: a qualitative study. 英国黑人加勒比海地区年轻成年人参与性传播感染检测的障碍:一项定性研究。
IF 1.6 4区 医学 Q3 INFECTIOUS DISEASES Pub Date : 2024-03-01 DOI: 10.1071/SH23166
Gemma Heath, Kiranpal Kaur, Claire Farrow, Jonathan D C Ross, Rebecca Clarke

Background: The Black Caribbean population have a disproportionately high burden of sexually transmitted infections (STIs) compared with other ethnic groups. The aim of this study was to explore barriers to engagement with STI testing within a UK-based young adult Black Caribbean community.

Methods: Semi-structured interviews were carried out with 14 young adults from the Black Caribbean community and six sexual healthcare professionals. Data were analysed thematically. A focus group of five young adults was conducted to refine themes.

Results: Data analysis generated three themes: (1) culturally embedded stigma; (2) historically embedded mistrust; and (3) lack of knowledge. Perceived as 'dirty', particularly for females, infection with STIs was stigmatised by religious conceptions of 'purity' and shame. This presented challenges in terms of cultural acceptability of talking about STI testing with partners, friends, and family. Legacies of colonialism, medical racism and malpractice compromised young people's trust in medical intervention and confidentiality of data management. A lack of knowledge related to STIs and their treatment, and in how to access and perform STI tests further served as a barrier. Culturally tailored interventions targeting these factors and delivered by radio, podcasts and social media were highlighted as having potential to improve engagement with STI testing.

Discussion: Engagement with STI testing by young adults from the Black Caribbean community is impacted by historically and culturally embedded teachings, practices and beliefs inherited through generations. Targeting these factors within culturally tailored interventions may be effective for increasing STI-testing, and thus reducing rates of STI-infection in this population.

背景:与其他种族群体相比,加勒比海黑人的性传播感染(STI)负担过重。本研究的目的是在英国的一个年轻的加勒比海黑人社区中探讨参与性传播感染检测的障碍:方法:对 14 名加勒比海黑人社区的年轻人和 6 名性保健专业人员进行了半结构式访谈。对数据进行了专题分析。结果:数据分析产生了三个主题:(1)"性",(2)"爱",(3)"性":数据分析产生了三个主题:(1) 文化上的成见;(2) 历史上的不信任;(3) 缺乏知识。感染性传播疾病被认为是 "肮脏的",尤其是对女性而言,宗教中关于 "纯洁 "和羞耻的观念使其蒙受耻辱。这给与伴侣、朋友和家人谈论性传播感染检测的文化接受度带来了挑战。殖民主义、医疗种族主义和渎职的遗留问题损害了年轻人对医疗干预和数据管理保密性的信任。对性传播感染及其治疗以及如何获得和进行性传播感染检测缺乏了解也是一个障碍。针对这些因素,通过广播、播客和社交媒体进行有文化针对性的干预,有可能提高性传播感染检测的参与度:讨论:加勒比黑人社区的年轻成年人参与性传播感染检测受到历史和文化上世代相传的教义、习俗和信仰的影响。针对这些因素采取有文化针对性的干预措施可能会有效提高性传播感染检测率,从而降低这一人群的性传播感染率。
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引用次数: 0
Harm reduction and multidisciplinary consultations for gay, bisexual, and other men who have sex with men practising chemsex based in a French infectious disease unit: patients' characteristics and perceptions. 法国传染病科为男同性恋、双性恋和其他男男性行为者提供的减低伤害和多学科咨询:患者的特点和看法。
IF 1.6 4区 医学 Q3 INFECTIOUS DISEASES Pub Date : 2024-03-01 DOI: 10.1071/SH23165
Alexandre Aslan, David Lessard, Bertrand Lebouché, Iris Bichard, Bénédicte Loze, Eleonore Laussat, Jean-Michel Molina

Background: Chemsex, a type of sexualised drug use, is expanding among gay, bisexual, and other men who have sex with men (GBMSM), with physical and mental health risks. Health-seeking behaviours of GBMSM practising chemsex is not clear.

Methods: Harm reduction (HR) consultations for GBMSM engaging in chemsex and seeking comprehensive services including HR were offered in a Parisian infectious disease unit. From December 2021 to January 2022, HR consultation patients completed an online survey on their consumption, health, used services, and perspective on consultations. We generated descriptive statistics, and tested (χ 2 ) the relationship between reporting a specialised follow-up and perceived usefulness of intervention.

Results: Of 172 patients, a total of 96 GBMSM (55.2%) completed the survey. Most ever consumed substance was 3-methylmethcathinone (3MMC; 92/96; 95.8%). Before consultations, about half consumed at least once a week (50/96; 52%), most reported negative impacts of chemsex on their social (60/96, 62.5%), professional (56/96, 58.3%), intimate (53/96; 55.21%), or sexual life (52/96; 54.17%). Also, more than two-thirds (n =57; 69.38%) had received a follow-up in specialised services: one-third had been followed in addictology (28/96, 29.2%) and/or psychotherapy (32/96, 33.3%), and one-fourth (24/96, 25.0%) had used emergency services. After consultations, three-quarters perceived the intervention as useful (n =74; 77.08%); we found no significant relationship with receiving a specialised follow-up; and most were satisfied with professionals' listening (90/96; 93.8%), and reported reduced risks (80/96; 83.3%).

Discussion: Multidisciplinary HR, preventive, diagnostical, and therapeutic sexological and psychiatric interventions are greatly needed among GBMSM practising chemsex. HR interventions accessible in services already attended by GBMSM are a valuable option.

背景:在男同性恋、双性恋和其他男男性行为者(GBMSM)中,"化学性交"(Chemsex)作为一种性化药物使用正在扩大,并带来了身心健康风险。方法:在巴黎的一家传染病科为从事化学性性行为的男同性恋、双性恋和其他男男性行为者提供减低伤害(HR)咨询,并寻求包括HR在内的综合服务。从 2021 年 12 月到 2022 年 1 月,HR 咨询患者完成了一项在线调查,内容涉及他们的消费、健康、使用过的服务以及对咨询的看法。我们进行了描述性统计,并检验了(χ2)报告专业随访与感知干预有用性之间的关系:在 172 名患者中,共有 96 名 GBMSM(55.2%)完成了调查。曾服用最多的药物是 3-甲基甲卡西酮(3MMC;92/96;95.8%)。在接受咨询前,约有一半的人每周至少吸食一次(50/96;52%),大多数人表示化学性行为对他们的社交(60/96,62.5%)、职业(56/96,58.3%)、亲密关系(53/96;55.21%)或性生活(52/96;54.17%)产生了负面影响。此外,超过三分之二(n=57;69.38%)的人接受过专业服务机构的随访:三分之一接受过成瘾学(28/96,29.2%)和/或心理治疗(32/96,33.3%)的随访,四分之一(24/96,25.0%)的人使用过急救服务。会诊后,四分之三的人认为干预措施是有用的(n=74;77.08%);我们发现干预措施与接受专业随访没有显著关系;大多数人对专业人员的倾听表示满意(90/96;93.8%),并报告说风险降低了(80/96;83.3%):讨论:从事化学性性行为的男童、女童和青少年亟需多学科的人力资源、预防、诊断和治疗性学和精神病学干预措施。在已有的服务机构中,对性别、性健康和心理健康进行干预是一种很有价值的选择。
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引用次数: 0
Could late-latent syphilis be treated with a single subcutaneous infusion of long-acting penicillin? 晚期梅毒能否通过一次皮下注射长效青霉素来治疗?
IF 1.6 4区 医学 Q3 INFECTIOUS DISEASES Pub Date : 2024-03-01 DOI: 10.1071/SH24003
Thel K Hla, Sam Salman, Joseph Kado, Brioni R Moore, Laurens Manning

Syphilis is an important global health threat and little has changed in its treatment since the mid-20th century. For late-latent or syphilis infection of unknown duration, the standard treatment of multiple intramuscular injections of benzathine penicillin G (BPG) are associated with significant pain and distress to clients and caregivers, negatively impacting on treatment completion. Based on pharmacokinetic modelling from a Phase I study of subcutaneous infusion of high dose BPG (SCIP), we present its feasibility, safety and tolerability for treatment of syphilis in a single infusion. SCIP leads to more sustained penicillin concentrations above the desired target with less reported pain and reduced clinic visits.

梅毒是一种严重威胁全球健康的疾病,自20世纪中期以来,梅毒的治疗方法几乎没有任何改变。对于晚期或病程不明的梅毒感染,多次肌肉注射苄星青霉素 G(BPG)的标准治疗方法会给患者和护理人员带来极大的痛苦和困扰,对完成治疗产生负面影响。根据高剂量苄星青霉素 G 皮下注射(SCIP)I 期研究的药代动力学模型,我们介绍了单次输注治疗梅毒的可行性、安全性和耐受性。SCIP能使青霉素浓度更持久地超过预期目标,同时减少疼痛,减少就诊次数。
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引用次数: 0
Effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus (COVID-19) vaccination on male fertility. 严重急性呼吸系统综合征冠状病毒 2 (SARS-CoV-2) 和冠状病毒 (COVID-19) 疫苗接种对男性生育能力的影响。
IF 1.6 4区 医学 Q3 INFECTIOUS DISEASES Pub Date : 2024-03-01 DOI: 10.1071/SH23191
Fei Chen, Yunfei Zhang, Yingze Zhang, Yuqi Li, Jiao Ma, Yining Qin, Shuwen Deng, Yuhan Zhang, Deyang Wang, Haiying Wang, Juan Lin

Coronavirus disease 2019, which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), remains an ongoing global public health challenge. This disease causes damage not only to the respiratory system, affecting the normal physiological function of the lungs, but also to other vital organs, such as the heart and testicles. Existing studies have shown that co-expression of angiotensin-converting enzyme 2 and transmembrane serine protease 2 is the main mechanism by which SARS-CoV-2 invades host cells. Angiotensin-converting enzyme 2-expressing cells are widespread in the corpus cavernosum, reproductive tract and testis of men, which has raised concerns. Furthermore, abnormal sex hormone levels and decreased semen parameters were observed in coronavirus disease 2019 patients. This study comprehensively assessed the effects of SARS-CoV-2 infection on the testis, semen parameters, sex hormone levels and erectile function, and discussed possible transmission routes during sexual intercourse and the effect of vaccination on male fertility.

由严重急性呼吸系统综合征冠状病毒 2(SARS-CoV-2)引起的 2019 年冠状病毒病仍然是一个持续的全球公共卫生挑战。这种疾病不仅会对呼吸系统造成损害,影响肺部的正常生理功能,还会对心脏和睾丸等其他重要器官造成损害。现有研究表明,血管紧张素转换酶 2 和跨膜丝氨酸蛋白酶 2 的共同表达是 SARS-CoV-2 侵入宿主细胞的主要机制。血管紧张素转换酶 2 表达细胞广泛存在于男性的海绵体、生殖道和睾丸,这引起了人们的关注。此外,在冠状病毒病 2019 年患者中观察到性激素水平异常和精液参数下降。本研究全面评估了SARS-CoV-2感染对睾丸、精液参数、性激素水平和勃起功能的影响,并探讨了性交过程中可能的传播途径以及接种疫苗对男性生育能力的影响。
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引用次数: 0
Corrigendum to: Oestradiol implants for gender-affirming hormone therapy: an observational study of serum oestradiol levels and consumer survey. 更正:用于性别确认激素疗法的雌二醇植入物:血清雌二醇水平观察研究和消费者调查。
IF 1.6 4区 医学 Q3 INFECTIOUS DISEASES Pub Date : 2024-03-01 DOI: 10.1071/SH23126_CO
Joanna Mesure, Sarjana Afrin, Sandra Fitzgerald, Judy Luu, Alison Gibberd, Lucy Leigh, Katie Wynne
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Sexual health
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