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Risk Factors Portending a Total Hip Arthroplasty for Patients Who Have Osteonecrosis of the Femoral Head. 股骨头骨坏死患者接受全髋关节置换术的风险因素。
IF 0.8 Q4 SURGERY Pub Date : 2024-07-15 DOI: 10.52198/24.STI.44.OS1756
Zhongming Chen, Jeremy A Dubin, Sandeep S Bains, Daniel Hameed, Mallory C Moore, Ronald E Delanois, Michael A Mont, James Nace

Introduction: Osteonecrosis of the femoral head (ONFH) poses a substantial burden to orthopaedic surgeons. However, the exact risk attributed by each specific patient factor for those who end up receiving a total hip arthroplasty (THA) are not well known. We assessed: (1) patient demographics (age and sex); (2) blood cell dyscrasias (sickle-cell disease and hypercoagulable states); and (3) substance use (oral corticosteroid use, tobacco use, and alcohol abuse).

Materials and methods: A retrospective search examined all patients who had a primary THA (n=715,100) between January 1, 2010 and April 30, 2020 using a national, all-payer database. Risk factors studied included age, sex, sickle-cell, hypercoagulable state, oral corticosteroid use, tobacco use, and alcohol abuse.

Results: Several risk factors were found to be significantly predictive for ONFH requiring THA: age <55 years (odds ratio [OR] 1.02, 95% confidence interval [CI] of 1.01 to 1.02, p<0.001), men (OR 1.07, 95% CI of 1.04 to 1.10, p<0.001), oral corticosteroid use (OR 1.21, 95% CI of 1.17 to 1.25, p<0.001), tobacco use (OR 1.15, 95% CI of 1.11 to 1.18, p<0.001), and alcohol abuse (OR 1.05, 95% CI of 1.01 to 1.08, p=0.009).

Conclusions: Based on the results of this study, young age, men, oral corticosteroid use, tobacco use, and alcohol abuse are risk factors for patients who have ONFH and had a THA. The degree of risk from greatest to least were: oral corticosteroid use, tobacco use, men, alcohol abuse, and age <55 years old.

简介:股骨头骨坏死(ONFH)给骨科外科医生带来了沉重的负担。然而,对于最终接受全髋关节置换术(THA)的患者来说,每个特定患者因素所带来的确切风险并不十分清楚。我们评估了:(1) 患者的人口统计学特征(年龄和性别);(2) 血细胞异常(镰状细胞病和高凝状态);(3) 药物使用(口服皮质类固醇、吸烟和酗酒):回顾性检索使用一个全国性的全付费者数据库,研究了 2010 年 1 月 1 日至 2020 年 4 月 30 日期间所有接受过初级 THA 的患者(n=715,100)。研究的风险因素包括年龄、性别、镰状细胞、高凝状态、口服皮质类固醇、吸烟和酗酒:结果:发现几个风险因素可显著预测需要接受 THA 的 ONFH:年龄:根据这项研究的结果,年轻、男性、口服皮质类固醇、吸烟和酗酒是 ONFH 患者接受 THA 手术的风险因素。风险程度从大到小依次为:口服皮质类固醇、吸烟、男性、酗酒和年龄。
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引用次数: 0
An Overview of Research for the Application of a Novel Biofilm-Preventing Surgical Irrigation System for Total Joint Arthroplasty Procedures in Order to Reduce the Risk of Periprosthetic Infection. 在全关节成形术中应用新型生物膜预防手术冲洗系统以降低假体周围感染风险的研究综述。
IF 0.8 Q4 SURGERY Pub Date : 2024-07-15 DOI: 10.52198/24.STI.44.OS1780
Sean B Sequeira, Matthew F Myntti, Jeanne Lee, Michael A Mont

Periprosthetic joint infection (PJI) is a serious postoperative complication in joint arthroplasty procedures that carries substantial morbidity and mortality associated with it. Several strategies have been developed both in the preoperative, perioperative, and postoperative periods to both combat and prevent the development of this devastating complication. Intraoperative irrigation is an important modality used during arthroplasty procedures prior to the implantation of final components that seeks to eradicate any biofilm formation. In this updated review, we discuss the XPERIENCE™ Advanced Surgical Irrigation solution (Next Science, Jacksonville, Florida) and the various completed, ongoing, and planned basic science and clinical investigations associated with it. Although there is already an impressive body of literature supporting its widespread utilization, future basic and clinical trials will continue to be performed to comprehensively characterize the effect this antimicrobial solution has on eliminating the risk of PJI following arthroplasty procedures.

假体周围关节感染(PJI)是关节置换术的一种严重术后并发症,发病率和死亡率都很高。在术前、围术期和术后,人们已经制定了多种策略来应对和预防这种破坏性并发症的发生。术中灌洗是关节成形术中植入最终组件前使用的一种重要方式,旨在根除任何生物膜的形成。在这篇最新综述中,我们将讨论 XPERIENCE™ 高级手术冲洗解决方案(Next Science,佛罗里达州杰克逊维尔市)以及与之相关的各种已完成、进行中和计划中的基础科学和临床研究。尽管已有大量文献支持其广泛应用,但未来仍将继续进行基础和临床试验,以全面描述这种抗菌溶液对消除关节成形术后 PJI 风险的作用。
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引用次数: 0
Impact of Synthetic Extracellular Matrices in Combination Therapy with Amniotic Allografting in the Treatment of Diabetic Foot Wounds: A Case Series. 合成细胞外基质与羊膜异体移植联合疗法在治疗糖尿病足伤口中的影响:病例系列。
IF 0.8 Q4 SURGERY Pub Date : 2024-07-15 DOI: 10.52198/24.STI.44.WH1770
Arthur Evensen, Jodi Walters, James Dancho, Valarie Samoy, David Jolley

Synthetic extracellular matrices are artificial polymers that are elongated and deposited as a matrix of nanofibers which mimic the native extracellular matrix. RenovoDerm® Anthem™ Wound Matrix (Columbus, Ohio) is comprised of polyglycolic acid and poly (L-lactide-co-caprolactone) which degrade by hydrolysis into a-hydroxy and fatty acids, lowering the pH and promoting regenerative cellular activity including angiogenesis. Amniotic allografts contain growth factors, cytokines, amino acids, extracellular matrix proteins, and hyaluronic acid which are recognized as intrinsic to the wound healing process. Synthetic extracellular matrices alone or in combination with amnio allografts do not have large bodies of evidence which demonstrate their effectiveness in the treatment of wounds. Presently, no prior studies have been performed to assess what impact these therapies may have on wound healing when used concurrently. The aim of this investigation was to assess whether a synergistic effect is produced with combination therapy using synthetic extracellular matrix and amniotic allografting. In this article, we present four cases of diabetic foot ulcerations treated with combination therapy. An amniotic fluid allograft, and/or membrane amniotic allograft, was implanted with a synthetic extracellular matrix dressing over top of the graft(s) at weekly intervals. All wounds demonstrated a greater than 80% decrease in wound size within four applications and achieved more than 95% wound closure after six applications.

人工合成细胞外基质是一种人工聚合物,它被拉长并沉积为纳米纤维基质,可模仿原生细胞外基质。RenovoDerm® Anthem™ Wound Matrix(俄亥俄州哥伦布市)由聚乙醇酸和聚(L-乳酸-共己内酯)组成,可通过水解降解为 a- 羟基和脂肪酸,降低 pH 值,促进包括血管生成在内的细胞再生活动。羊膜异体移植物含有生长因子、细胞因子、氨基酸、细胞外基质蛋白和透明质酸,这些被认为是伤口愈合过程中的内在因素。合成细胞外基质单独使用或与羊膜异体移植物结合使用时,并没有大量证据证明其在治疗伤口方面的有效性。目前,还没有研究评估这些疗法同时使用会对伤口愈合产生什么影响。本研究旨在评估使用合成细胞外基质和羊膜异体移植的联合疗法是否会产生协同效应。本文介绍了四例采用联合疗法治疗糖尿病足溃疡的病例。羊水同种异体移植和/或羊膜同种异体移植与合成细胞外基质敷料一起植入,每周一次。使用四次后,所有伤口的面积都缩小了 80% 以上,使用六次后,伤口闭合率达到 95% 以上。
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引用次数: 0
The Perspectives of Robotic Surgeons. 机器人外科医生的观点。
IF 0.8 Q4 SURGERY Pub Date : 2024-07-15 DOI: 10.52198/24.STI.44.SO1785
Agostino Cervone, Joshua Rainey, Nipun Sodhi, Michael A Mont

Given recent advancements in artificial intelligence and robotic surgery, attention has now been paid to the concept of autonomous surgery. As robotic surgery has developed and matured, examples of autonomous surgery have arisen through the assistance of artificial intelligence. As with any new technology, ethical and legal considerations also arise, and there are special considerations that should be taken into account with the adaptation of new technology involving patient care. In this paper, we will describe autonomous surgery used in general surgery and lower extremity joint arthroplasty, and we will highlight the current ethical and legal considerations associated with this technology.

鉴于人工智能和机器人外科手术的最新进展,自主外科手术的概念现已受到关注。随着机器人手术的发展和成熟,在人工智能的协助下出现了自主手术的实例。与任何新技术一样,伦理和法律方面的考虑因素也会随之出现,而且在采用涉及病人护理的新技术时还应考虑到一些特殊因素。在本文中,我们将介绍自主手术在普通外科和下肢关节置换术中的应用,并着重介绍当前与该技术相关的伦理和法律问题。
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引用次数: 0
The Cosmetic Management of Mons Pubis Ptosis. 耻骨下垂的美容治疗。
IF 0.8 Q4 SURGERY Pub Date : 2024-07-15 DOI: 10.52198/24.STI.44.GY1797
Marco Pelosi, Marco Pelosi, Marianne Pelosi

Introduction: Achieving excellent cosmetic monsplasty results consistently can be difficult. Undertreatment or overtreatment of the fatty ptotic mons pubis will yield suboptimal results. A stepwise tactical approach to the monsplasty eliminates these problems and produces excellent aesthetic results.

Materials and methods: The surgical management of monsplasty requires individualization and careful surgical planning. The authors' approach illustrating the steps and tactics to perform monsplasty is presented. Based on our experience with 1,200 cases, a comprehensive clinical classification of mons pubis ptosis with surgical guidelines for treatment was created.

Results: Over 1200 patients have undergone monsplasty using the authors' stepwise tactical approach to mons rejuvenation. No complications associated with the monsplasty occurred. Patient satisfaction with the monsplasty was very high.

Conclusion: In the authors' experience, the preoperative grading of the mons pubis ptosis and the use of guidelines produces consistently excellent aesthetic results. Monsplasty is associated with high aesthetic and functional patient satisfaction.

简介要持续获得出色的阴阜整形美容效果是很困难的。对下垂的耻骨脂肪治疗不足或治疗过度都会产生不理想的效果。采用循序渐进的战术方法进行耻骨联合成形术可消除这些问题,并获得极佳的美容效果:阴阜成形术的手术管理需要个体化和仔细的手术规划。本文介绍了作者的方法,说明了实施下颌骨整形术的步骤和策略。根据我们 1200 例病例的经验,创建了耻骨上睑下垂的综合临床分类和手术治疗指南:结果:1200 多名患者接受了作者提出的阴阜整形术分步战术方法。没有出现与下颌骨整形术相关的并发症。结果:1200 多名患者接受了作者的下颌骨整形术,没有出现与下颌骨整形术相关的并发症,患者对下颌骨整形术的满意度非常高:根据作者的经验,术前对耻骨上睑下垂进行分级,并使用相关指南,可持续获得极佳的美学效果。耻骨联合成形术在美学和功能方面都能获得患者的高度满意。
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引用次数: 0
Modular Revision System for Complex Hip Revisions: A Case Series. 用于复杂髋关节翻修的模块化翻修系统:病例系列。
IF 0.8 Q4 SURGERY Pub Date : 2024-07-15 Epub Date: 2024-03-01 DOI: 10.52198/24.STI.44.OS1757
Daniel Hameed, Brittany Oster, Bryan D Springer, Arthur L Malkani, Michael A Mont

Revision total hip arthroplasty (THA) is a procedure with many challenges, especially when patients exhibit femoral bone defects. The causes of these defects vary, ranging from removal of prior implants to aseptic loosening. As surgeons navigate these challenges, a reliable surgical system is important. One modular fluted tapered system provides surgeons with tools to address complex hip revision cases. Introduced in 2003, this system has been utilized in over 180,000 procedures, demonstrating its reliability and effectiveness. Previously, the body stem came in sizes 155mm to 235mm. In the discussed case series, we present six distinct patient cases that highlight the advantages and efficacy of a newly introduced modification of the system; that is the use of smaller stemmed components (now 115mm). With each patient presenting unique challenges, we have demonstrated the use of this new short-stem version for multiple applications for various revision scenarios.

翻修全髋关节置换术(THA)是一项充满挑战的手术,尤其是当患者出现股骨头缺损时。造成这些缺陷的原因多种多样,从先前植入物的移除到无菌性松动,不一而足。外科医生在应对这些挑战时,可靠的手术系统非常重要。一种模块化凹槽锥形系统为外科医生提供了处理复杂髋关节翻修病例的工具。该系统于2003年推出,已用于超过18万例手术,证明了其可靠性和有效性。以前,髋臼体柄的尺寸从155毫米到235毫米不等。在讨论的病例系列中,我们介绍了六个不同的患者病例,突出强调了新引进的系统改良的优势和有效性,即使用较小的柄部件(现在为 115 毫米)。由于每位患者都面临着独特的挑战,我们展示了这种新型短茎式组件在各种翻修情况下的多种应用。
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引用次数: 0
Advancements in Donation after Circulatory Death Heart Procurement and Preservation: A Comprehensive Review of Recent Innovations. 循环死亡后心脏采集和保存捐赠的进展:近期创新的全面回顾。
IF 0.8 Q4 SURGERY Pub Date : 2024-07-15 DOI: 10.52198/24.STI.44.CV1801
Ignazio Condello

Introduction: The persistent shortage of donor hearts for transplantation has prompted exploration into Donation after Circulatory Death (DCD) as a promising avenue for organ procurement. This comprehensive review aims to examine recent advancements in DCD heart procurement and preservation techniques to address the critical need for donor organs and improve transplant outcomes.

Materials and methods: A systematic review was conducted to identify relevant studies and innovations related to DCD heart procurement and preservation. Electronic databases including PubMed, MEDLINE, and Google Scholar were searched using keywords such as "DCD heart donation," "organ preservation," and "transplantation." Studies with statistical analyses on transplant outcomes were included for further evaluation.

Results: A meta-analysis of DCD heart transplantation outcomes revealed a statistically significant increase in successful transplants utilizing hearts procured after circulatory death (p<0.05). Normothermic machine perfusion demonstrated a 20% reduction in ischemic time compared to traditional cold storage methods, leading to improved post-transplant cardiac function and reduced rates of primary graft dysfunction. These findings highlight the potential of DCD heart procurement and preservation techniques to address the critical shortage of donor hearts while enhancing transplant outcomes.

Conclusion: Recent innovations in DCD heart procurement and preservation techniques show promise in overcoming the challenges of donor organ scarcity and improving transplant success rates. Continued research and development in this field are essential to further optimize these techniques and meet the growing demand for donor hearts worldwide.

导言:用于移植的供体心脏的持续短缺促使人们探索循环死亡后捐献(DCD),将其作为器官获取的一种有前途的途径。这篇综合综述旨在研究 DCD 心脏获取和保存技术的最新进展,以满足对捐献器官的迫切需求并改善移植结果:为确定与 DCD 心脏获取和保存相关的研究和创新,我们进行了系统性综述。使用 "DCD 心脏捐献"、"器官保存 "和 "移植 "等关键词搜索了包括 PubMed、MEDLINE 和 Google Scholar 在内的电子数据库。纳入了对移植结果进行统计分析的研究,以作进一步评估:结果:对 DCD 心脏移植结果的荟萃分析表明,利用在循环死亡后获取的心脏进行移植的成功率在统计学上有显著提高(p):DCD 心脏获取和保存技术的最新创新表明,有望克服供体器官稀缺的挑战并提高移植成功率。要进一步优化这些技术,满足全球对捐献心脏日益增长的需求,就必须在这一领域继续进行研究和开发。
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引用次数: 0
The Clinical Utility of Powdered and Flowable Matrices in Wound Repair and Tissue Regeneration. 粉末和可流动基质在伤口修复和组织再生中的临床应用
IF 0.8 Q4 SURGERY Pub Date : 2024-07-15 DOI: 10.52198/24.STI.44.WH1788
Allegra L Fierro, Nour Hijazi, Carolyn Foley, Lauren Rodio, John C Lantis

Cellular and matrix-like products come in many forms. Among them, powdered and micronized formulations have become increasingly available and popular owing to their unique properties and advantages. Powders have increased tissue contact which many believe can enhance granulation tissue formation, they fill irregular and deep cavities, and they can be used in concert with sheet-like products and skin grafts for improved healing. Despite their advantages, powdered products do have certain limitations that hinder their use, including poor insurance coverage and a lack of CPT coding for adequate reimbursement in an outpatient setting, making their use primarily limited to the operating room. Also, most published data on powdered products consists of smaller case studies and case series, with few reports evaluating the efficacy and utility of powdered formulations compared to their sheet-like progenitors. In this manuscript, we organize available powdered matrix products by type of substrate: xenograft, allograft, placental-based, and synthetic, and review the data in support of various products in specific wound types. This review of the supporting literature provides the current body of evidence on the utility of powdered matrices in wounds.

细胞和类基质产品有多种形式。其中,粉末状和微粉化制剂因其独特的性能和优势,越来越多地受到人们的青睐。粉末可增加与组织的接触,许多人认为这可促进肉芽组织的形成,粉末可填充不规则的深腔,还可与片状产品和植皮产品配合使用,以改善愈合。尽管粉末产品有很多优点,但它们也有一些局限性,阻碍了它们的使用,包括保险覆盖率低,缺乏 CPT 编码,无法在门诊环境中获得足够的报销,因此它们的使用主要局限于手术室。此外,已发表的有关粉末产品的数据大多是小型病例研究和系列病例,很少有报告评估粉末制剂与其片状制剂相比的疗效和实用性。在本手稿中,我们按基质类型对现有的粉末基质产品进行了整理:异种基质、同种基质、胎盘基质和合成基质,并回顾了各种产品在特定伤口类型中的支持数据。这篇文献综述提供了目前有关粉末基质在伤口中应用的证据。
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引用次数: 0
Twenty First Century Technological Toolbox Innovation for Transanal Minimally Invasive Surgery (TAMIS). 经肛门微创手术 (TAMIS) 的二十一世纪技术工具箱创新。
IF 0.8 Q4 SURGERY Pub Date : 2024-07-15 DOI: 10.52198/24.STI.44.GS1760
Alice Moynihan, Patrick Boland, Ronan A Cahill

Transanal minimally invasive surgery (TAMIS) is an effective procedure that plays an important role in the care of patients with significant rectal neoplasia and polyps including early-stage cancers. However, it is perhaps underutilised and under threat from both advanced flexible endoscopic procedures and proceduralists (who often act as gatekeepers for referral to colorectal surgeons), as well as from robotic surgery proponents. TAMIS advocates can learn and adopt practice insights from both these fields and incorporate available technological innovations building on the huge accomplishments already delivered in this area. Evolved practice through technology has the potential to offset current limitations regarding technical constraints and indeed patient selection (via artificial intelligence methods). Potential target areas for advances are considered in this review from different perspectives: (1) Access (2) Insufflation (3) Visualisation (4) Disease Characterization in situ, and (5) Tissue Handling and Suturing. While a bundle approach may be most useful, the advances for each component are potentially useful in their own right and could be applied without depending on the other practices detailed so that more accurate (and perhaps even numerically more) TAMIS procedures can be performed globally to improve patient care.

经肛门微创手术(TAMIS)是一种有效的治疗方法,在治疗患有严重直肠肿瘤和息肉(包括早期癌症)的患者方面发挥着重要作用。然而,这种手术可能未得到充分利用,并受到先进的柔性内窥镜手术和手术医师(他们通常是转诊给结直肠外科医生的守门人)以及机器人手术支持者的威胁。TAMIS 的倡导者可以学习和采纳这两个领域的实践经验,并在该领域已取得巨大成就的基础上融入现有的技术创新。通过技术发展的实践有可能抵消目前在技术限制和患者选择(通过人工智能方法)方面的局限性。本综述从不同角度探讨了可能取得进展的目标领域:(1)进入(2)充气(3)可视化(4)原位疾病特征描述,以及(5)组织处理和缝合。虽然捆绑式方法可能最有用,但每个组成部分的进展本身也可能有用,并且可以在不依赖于其他详细做法的情况下应用,这样就可以在全球范围内执行更准确(甚至更多数字)的 TAMIS 程序,从而改善患者护理。
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引用次数: 0
The Science of Stapling: Staple Form. 订书的科学:订书钉的形式
IF 0.8 Q4 SURGERY Pub Date : 2024-07-15 Epub Date: 2024-03-19 DOI: 10.52198/24.STI.44.GS1773
Prachi Rojatkar, Anil K Nalagatla, Crystal D Ricketts, Jeffrey W Clymer, Emily Yosh

Surgical stapling has evolved significantly over time, with the primary goal of improving patient outcomes. This study describes the technological advancements in surgical stapling from the perspective of staple and cartridge design, assessing the impact of staple design when it changes from the traditional B form (also known as 2D staple form) to a three-dimensional form (known as 3D staple form). The change in configuration helps compress a larger surface area of the tissue. The 3D configuration is designed to optimize compression not only underneath each staple but also across staples and multiple staple lines, including both stapled and unstapled regions of the tissue. By achieving more evenly distributed compression throughout the staple line, there is potential for reduced leak paths. The study demonstrates that the 3D staple form in surgical stapling results in more evenly distributed compression. In the future, this advanced technology should seamlessly integrate into emerging systems such as the surgical robot, enabling continued progress in surgical instrumentation and ultimately in surgical care.

随着时间的推移,以改善患者预后为主要目标的手术缝合技术发生了重大发展。本研究从钉书针和针筒设计的角度描述了手术钉书针的技术进步,评估了钉书针设计从传统的 B 形(也称为 2D 钉书针形式)转变为三维形式(称为 3D 钉书针形式)时所产生的影响。结构的改变有助于压缩更大的组织表面积。三维结构的设计不仅优化了每个订书钉下方的压缩,还优化了跨订书钉和多条订书钉线的压缩,包括组织的订书钉区域和未订书钉区域。通过在整个缝合线上实现更均匀分布的压缩,有可能减少渗漏路径。这项研究表明,手术缝合中的三维缝合线可实现更均匀分布的压迫。未来,这项先进技术应能无缝集成到手术机器人等新兴系统中,从而推动手术器械的不断进步,并最终促进手术护理的发展。
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引用次数: 0
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Surgical technology international
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