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Effect of Various Ancillary Operating Room Techniques on Wound Healing Outcomes After Total Hip Arthroplasty. 各种手术室辅助技术对全髋关节置换术后伤口愈合效果的影响
Q3 Medicine Pub Date : 2023-12-29 DOI: 10.52198/23.STI.43.OS1749
Daniel Hameed, Jeremy A Dubin, Sandeep S Bains, Tim Board, Ryan Nunley, Michael A Mont

Introduction: The successful management of wound healing following total hip arthroplasty (THA) is multifaceted, relying on various intraoperative techniques and surgical variables. Recent reviews have evaluated many of these factors, including the comparison between mesh-adhesive dressings and other skin closure methods, the closing time of different suture techniques, and the four aspects of closure for THA (deep fascial layer; subdermal layer; intradermal layer). However, previous articles did not cover certain topics that can be directly influenced by the surgeon. Specifically, these include the use of deep vein thrombosis (DVT) prophylaxis, the management of intraoperative drains, and the selection of surgical approaches. Therefore, in this comprehensive systematic review of the literature, we have focused on three factors that may influence wound healing. We evaluated the following: (1) the impact of different DVT prophylaxis methods on wound healing and infection rates; (2) the effects of intraoperative drain use on wound healing; (3) the influence of various surgical approaches on wound closure, and postoperative infection rates. By concentrating on these areas, this review aims to provide a more complete understanding of the factors that contribute to successful wound management after THA.

Materials and methods: A systematic search of electronic databases, including PubMed, Cochrane Library, Medline, and Embase, was conducted to identify studies assessing surgical variables and techniques, specifically focusing on DVT prophylaxis, intraoperative drain use, and surgical approaches and their impact on wound healing in THA. Relevant terms like "hip," "arthroplasty," "wound healing," "DVT prophylaxis," and "surgical approaches" refined the search, which included English language publications until May 1, 2023. Independent screening by two authors and a third mediator facilitated the selection process, with 13 studies meeting the criteria. Assessment of these studies involved evaluating their evidence level and methodological quality using the Modified Coleman Methodology Score (MCMS). A comparison was made on wound healing outcomes in THA, specifically focusing on the three factors outlined in the introduction: (1) the impact of different DVT prophylaxis methods on wound healing and infection rates; (2) the effects of intraoperative drain use on wound healing; and (3) the influence of various surgical approaches on wound closure and postoperative infection rates. Data synthesis for the studies provided a comprehensive summary, categorizing them by evidence level, and aimed to contribute to a more complete understanding of the factors that influence successful wound management after THA.

Results: In studies examining DVT prophylaxis for total knee arthroplasties (TKA), three reports found that both rivaroxaban and enoxaparin had similar wound infection rates at 0.36%. However,

在探讨手术方法时,DAA 和 PLA 的并发症发生率相当。然而,DAA类别中的特定技术在延迟伤口愈合方面表现出差异,尤其是在肥胖患者中。这些发现强调了手术选择在决定伤口愈合结果方面的微妙作用。随着 THA 领域的不断发展,外科医生必须充分了解情况,确保患者获得最佳治疗效果。
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引用次数: 0
Systematic Review of Local Anaesthetic Systemic Toxicity in Urology. 泌尿外科局麻药全身毒性系统性综述
Q3 Medicine Pub Date : 2023-12-29 DOI: 10.52198/23.STI.43.UR1725
Claris Oh, Stephen Kinnear, Derek Hennessey, James Adshead, Nikhil Vasdev, Ned Kinnear

Objective: To systematically evaluate cases of local anaesthetic systemic toxicity (LAST) in adult urological patients.

Methods: A search of the Cochrane, Embase, and Medline databases as well as grey literature from 1 January 1974 to 1 February 2023 was performed using reported methods. Reporting followed the Preferred Reporting Items for Systematic Review and Meta-analysis guidelines. Eligible studies were published in English, described LAST secondary to local anaesthetic administration by urological medical staff to an adult patient, and reported >1 symptom of LAST.

Results: One hundred fifty-seven publications were screened, and six eligible studies (all case reports) were identified, representing six cases of LAST in adult urological patients. Patients were aged 29-54 years and one was female. Cases occurred secondary to penile dorsal nerve block (two cases), scrotal self-injection (two), circumcision (one) or trans-vaginal tape insertion (one). Causative drugs were lidocaine (three patients; median dose 600mg) and bupivacaine (three; 200mg). While one patient was found deceased at home and received no treatment, five experienced LAST as inpatients and were discharged with no deficit. Three patients (50%) experienced a state of reduced consciousness or seizures, one experienced psychosis and one had asymptomatic tachyarrhythmia. Management consisted of supportive management (five patients), intravenous lipid emulsion (three) or intravenous thiopental and diazepam (one). Recommended tools suggested that two of these studies were at moderate or high risk of bias.

Conclusion: LAST is seen only rarely in adult urology. Most iatrogenic cases occur due to penile dorsal nerve block and most patients have no long-term sequelae. Urologists should be familiar with its presentation and management, and minimise risk by adhering to local anaesthetic maximum safe dose ranges.

目的:系统评估成人泌尿科患者的局麻药全身毒性(LAST)病例:系统评估成人泌尿科患者的局麻药全身毒性(LAST)病例:方法:采用报告方法对 Cochrane、Embase 和 Medline 数据库以及 1974 年 1 月 1 日至 2023 年 2 月 1 日的灰色文献进行检索。报告遵循《系统综述和元分析首选报告项目》指南。符合条件的研究均以英语发表,描述了泌尿科医务人员对成年患者实施局部麻醉后继发的LAST,并报告了>1种LAST症状:结果:共筛选出 157 篇出版物,并确定了 6 项符合条件的研究(均为病例报告),其中 6 例为成年泌尿科患者的 LAST 病例。患者年龄在 29-54 岁之间,其中一名患者为女性。病例继发于阴茎背神经阻滞(2 例)、阴囊自行注射(2 例)、包皮环切术(1 例)或经阴道胶带插入术(1 例)。致病药物为利多卡因(3 名患者;中位剂量 600 毫克)和布比卡因(3 名患者;200 毫克)。一名患者在家中死亡,未接受任何治疗,五名患者在住院期间经历了 LAST,出院时无任何缺陷。三名患者(50%)出现意识减退或癫痫发作,一名患者出现精神错乱,一名患者出现无症状性快速心律失常。治疗包括支持性治疗(5 名患者)、静脉注射脂质乳剂(3 名)或静脉注射硫喷妥类药物和地西泮(1 名)。推荐工具显示,其中两项研究存在中度或高度偏倚风险:结论:LAST在成人泌尿外科中很少见。大多数先天性病例发生于阴茎背神经阻滞,大多数患者没有长期后遗症。泌尿科医生应熟悉其表现形式和处理方法,并遵守局麻药最大安全剂量范围,将风险降至最低。
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引用次数: 0
An Overview of Recent Advances in Anterior Cervical Decompression and Fusion Surgery. 颈椎前路减压和融合手术的最新进展综述。
Q3 Medicine Pub Date : 2023-12-29 DOI: 10.52198/23.STI.43.NS1732
Marco Battistelli, Filippo Maria Polli, Quintino Giorgio D'Alessandris, Manuela D'Ercole, Alessandro Izzo, Alessandro Rapisarda, Nicola Montano

Anterior cervical diskectomy and fusion (ACDF) has evolved significantly in the last few years with the aim of enhancing effectiveness and safety while reducing hospitalization and healthcare-related costs. Transitioning from iliac crest autografts to allografts minimizes donor-site complications like pain, infections, and hematoma. Allograft options, such as polyetheretherketone (PEEK) and tantalum, vary in their osteoinductive properties and elastic modulus, influencing fusion rates, time, and the rate of subsidence. Recently introduced zero-profile cages offer bone fixation through screws, resulting in reduced blood loss, improved spinal alignment, and decreased complications like dysphagia and adjacent segment disease. Intraoperative neuromonitoring (IONM) has gained widespread use. The North American Spine Society (NASS) 2023 recommendations endorse IONM in cervical deformity corrections and myelopathy cases. Insufficient studies hinder clear radiculopathy recommendations, but emerging research supports IONM for patients at greater risk of C5 nerve root injury or positional injury. Advancements in hemostatic agents, such as gelatin sponges, oxidized cellulose, and fibrin sealants, contribute to safety by reducing postoperative hematoma rates and eliminating the need for drainage. Innovations like the exoscope, endoscope, and computed-tomography (CT) navigation have transformed surgical practices. Exoscopes are emerging as an alternative to microscopes, offering benefits like a smaller footprint, adjustable positioning, lower costs, and shared intraoperative views for educational purposes. The use of endoscope offers the possibility of performing a minimally invasive technique with improved results in terms of cosmesis and patient-perceived outcome. CT navigation can be useful in high-risk procedures, such as cervical plate placement for major instability. This paper provides an overview of cutting-edge technologies in ACDF surgery, emphasizing cage materials and designs, safety measures, and operating room advancements. It also highlights areas for future research, underlining the procedure's continuous evolution.

颈椎前路椎间盘切除与融合术(ACDF)在过去几年中得到了长足的发展,其目的是提高有效性和安全性,同时减少住院时间和医疗相关费用。从髂嵴自体移植物过渡到同种异体移植物可最大限度地减少供体部位的并发症,如疼痛、感染和血肿。聚醚醚酮(PEEK)和钽等同种异体移植物的骨诱导特性和弹性模量各不相同,会影响融合率、时间和下沉率。最近推出的零轮廓保持架通过螺钉进行骨固定,从而减少了失血,改善了脊柱排列,减少了吞咽困难和邻近节段疾病等并发症。术中神经监测(IONM)已得到广泛应用。北美脊柱学会(NASS)2023年建议认可在颈椎畸形矫正和脊髓病病例中使用术中神经监测仪。研究不足阻碍了明确的神经根病建议,但新兴研究支持对C5神经根损伤或位置性损伤风险较大的患者进行IONM。明胶海绵、氧化纤维素和纤维蛋白密封剂等止血剂的进步降低了术后血肿发生率,无需引流,从而提高了安全性。外窥镜、内窥镜和计算机断层扫描(CT)导航等创新技术改变了外科手术方法。外窥镜正在成为显微镜的替代品,它具有占地面积小、定位可调、成本低以及可共享术中视图用于教学等优点。内窥镜的使用为微创技术的实施提供了可能,并在外观和患者感知效果方面带来了改善。CT 导航可用于高风险手术,如治疗严重不稳的颈椎钢板置入术。本文概述了 ACDF 手术的前沿技术,重点介绍了保持架材料和设计、安全措施以及手术室的进步。本文还重点介绍了未来的研究领域,强调了该手术的不断发展。
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引用次数: 0
A New Hinge Prosthesis Offers Ease of Use and the Ability to Retain the Revision Tibial Baseplate. 新型铰链假体不仅易于使用,还能保留翻修后的胫骨底板。
Q3 Medicine Pub Date : 2023-12-29 DOI: 10.52198/23.STI.43.OS1746
Emily L Hampp, Daniel Hameed, Afshin Anoushiravani, Shilpa Donde, Sophie Hatcher, Jeremy A Dubin, Kerianne Coulon, Sarah Mastrandrea, Caroline Weinberg, Frank LoPiccolo, Michael A Mont

Total knee arthroplasty (TKA) is a widely practiced surgical procedure, with its efficacy underscored by the increasing number of patients benefiting from it. As primary TKAs rise, the orthopaedic community must prepare for a surge in complex primary and revision knee arthroplasties in the future. While most revisions use non-constrained or semi-constrained prostheses, certain scenarios require a fully constrained (hinge) prosthesis to address major ligamentous and/or bone loss. Over time, hinge designs have evolved, but outcomes with these designs have been mixed. To help address challenges seen with some earlier designs, a new modular revision solution has been designed for both primary and revision surgeries. This system has a new revision baseplate that has compatibilities with varying distal femoral components and introduces an enhanced hinge mechanism. This paper aims to explore the evolution of hinge designs, elaborate on the surgical workflows and intended compatibilities of this new revision hinge system in six different scenarios, and discuss its various potential advantages.

全膝关节置换术(TKA)是一种广泛应用的外科手术,越来越多的患者从中受益,这充分证明了它的疗效。随着初次全膝关节置换术的增多,矫形外科界必须为未来复杂的初次和翻修膝关节置换术的激增做好准备。虽然大多数翻修手术使用的是非受限或半受限假体,但在某些情况下需要使用全受限(铰链)假体来解决主要韧带和/或骨缺损问题。随着时间的推移,铰链设计也在不断发展,但这些设计的效果参差不齐。为了帮助解决一些早期设计所面临的挑战,我们设计了一种新的模块化翻修解决方案,既适用于初次手术,也适用于翻修手术。该系统有一个新的翻修基板,可兼容不同的股骨远端组件,并引入了增强型铰链机制。本文旨在探讨铰链设计的演变,详细介绍这种新型翻修铰链系统在六种不同情况下的手术流程和预期兼容性,并讨论其各种潜在优势。
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引用次数: 0
Endoscopic Gastric Plication: A Flexible and Tailored Alternative to Bariatric Surgery. 内镜胃折叠术:灵活、量身定制的减肥手术替代方案。
Q3 Medicine Pub Date : 2023-12-29 DOI: 10.52198/23.STI.43.GS1745
Francesco Frattini, Andrea Gambetti, Giuseppe Cordaro, Jerry Spisani, Georgios Lianos, Bertoli Simona, Gianlorenzo Dionigi

Introduction: Endoscopic procedures are expanding and have been evolving in recent years, increasing their volume along with the development of new devices. This is due to the low morbidity and complication rate, the reversibility of the procedures, and the positive impact on patients. Among the endoscopic procedures gaining interest is sleeve gastroplasty. It emerged as a feasible and safe alternative to traditional bariatric surgery. There are no guidelines available on the indications and use of endoscopic gastroplasty. The aim of this study is to present preliminary results of a case series of endoscopic gastric plication procedures performed for different options: as a primary endoscopic sleeve, as revision for sleeve gastrectomy, and as revision for gastric bypass.

Materials and methods: A retrospective analysis was performed on a prospective database collecting data on all patients with obesity treated with endoscopic gastroplasty with the Overstitch™ (Apollo Endosurgery, Inc., Austin, Texas) device from 2022 to 2023 in the bariatric surgery unit.

Results: Twenty-three patients were treated from May 2022 to July 2023 with endoscopic gastric plication. Ten patients (43%) were submitted to primary endoscopic sleeve gastroplasty, three patients to revision of sleeve gastrectomy, one patient to revision of one anastomosis gastric bypass, and eight patients received a revision of Roux-en-Y gastric bypass. The body mass index (BMI) of patients submitted to primary ESG ranged from 33 to 42kg/m2, with a mean BMI of 37kg/m2. The age of the patients ranged from 22 to 70 years, with a mean age of 45. In one case, we registered a Clavien-Dindo 2 complication-an inflammatory perigastric reaction without a collection occurred 15 days after a primary ESG.

Conclusion: Endoscopic gastric plication is emerging as a safe, mini-invasive, and effective procedure alternative to sleeve gastrectomy in patients with I or II class obesity or for those unfit for bariatric surgery. The endoscopic suturing device can be used both as a primary procedure or as a revisional option after failure of the primary surgery, thus proving to be a versatile option to provide to bariatric patients.

简介近年来,内窥镜手术不断扩展和发展,随着新设备的开发,手术量也在增加。这是因为内窥镜手术的发病率和并发症发生率低、可逆性强,而且对患者有积极的影响。在内窥镜手术中,袖状胃成形术越来越受到关注。它是传统减肥手术的一种可行且安全的替代方法。目前还没有关于内镜胃成形术适应症和使用的指南。本研究的目的是介绍内镜胃成形术的初步结果,该手术有不同的选择:内镜袖状胃成形术、袖状胃切除术的翻修术和胃旁路术的翻修术:对一个前瞻性数据库进行了回顾性分析,该数据库收集了2022年至2023年在减肥手术室使用Overstitch™(Apollo Endosurgery, Inc.,德克萨斯州奥斯汀)设备进行内镜胃成形术治疗的所有肥胖症患者的数据:2022年5月至2023年7月,23名患者接受了内镜胃成形术治疗。10名患者(43%)接受了初级内镜袖状胃成形术,3名患者接受了袖状胃切除术的改良,1名患者接受了单吻合胃旁路术的改良,8名患者接受了Roux-en-Y胃旁路术的改良。接受初治 ESG 的患者体重指数(BMI)从 33kg/m2 到 42kg/m2 不等,平均体重指数为 37kg/m2。患者的年龄从 22 岁到 70 岁不等,平均年龄为 45 岁。在一个病例中,我们发现了 Clavien-Dindo 2 并发症--在初治 ESG 术后 15 天出现了胃周炎症反应,但没有集结:结论:对于 I、II 级肥胖症患者或不适合接受减肥手术的患者来说,内镜胃成形术正在成为袖状胃切除术的一种安全、微创、有效的替代手术。内镜缝合装置既可作为初治手术,也可作为初治手术失败后的复诊选择,因此被证明是提供给减肥患者的一种多功能选择。
{"title":"Endoscopic Gastric Plication: A Flexible and Tailored Alternative to Bariatric Surgery.","authors":"Francesco Frattini, Andrea Gambetti, Giuseppe Cordaro, Jerry Spisani, Georgios Lianos, Bertoli Simona, Gianlorenzo Dionigi","doi":"10.52198/23.STI.43.GS1745","DOIUrl":"10.52198/23.STI.43.GS1745","url":null,"abstract":"<p><strong>Introduction: </strong>Endoscopic procedures are expanding and have been evolving in recent years, increasing their volume along with the development of new devices. This is due to the low morbidity and complication rate, the reversibility of the procedures, and the positive impact on patients. Among the endoscopic procedures gaining interest is sleeve gastroplasty. It emerged as a feasible and safe alternative to traditional bariatric surgery. There are no guidelines available on the indications and use of endoscopic gastroplasty. The aim of this study is to present preliminary results of a case series of endoscopic gastric plication procedures performed for different options: as a primary endoscopic sleeve, as revision for sleeve gastrectomy, and as revision for gastric bypass.</p><p><strong>Materials and methods: </strong>A retrospective analysis was performed on a prospective database collecting data on all patients with obesity treated with endoscopic gastroplasty with the Overstitch™ (Apollo Endosurgery, Inc., Austin, Texas) device from 2022 to 2023 in the bariatric surgery unit.</p><p><strong>Results: </strong>Twenty-three patients were treated from May 2022 to July 2023 with endoscopic gastric plication. Ten patients (43%) were submitted to primary endoscopic sleeve gastroplasty, three patients to revision of sleeve gastrectomy, one patient to revision of one anastomosis gastric bypass, and eight patients received a revision of Roux-en-Y gastric bypass. The body mass index (BMI) of patients submitted to primary ESG ranged from 33 to 42kg/m2, with a mean BMI of 37kg/m2. The age of the patients ranged from 22 to 70 years, with a mean age of 45. In one case, we registered a Clavien-Dindo 2 complication-an inflammatory perigastric reaction without a collection occurred 15 days after a primary ESG.</p><p><strong>Conclusion: </strong>Endoscopic gastric plication is emerging as a safe, mini-invasive, and effective procedure alternative to sleeve gastrectomy in patients with I or II class obesity or for those unfit for bariatric surgery. The endoscopic suturing device can be used both as a primary procedure or as a revisional option after failure of the primary surgery, thus proving to be a versatile option to provide to bariatric patients.</p>","PeriodicalId":22194,"journal":{"name":"Surgical technology international","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139088611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of Indocyanine Green Fluorescence During Total Thyroidectomy to Identify Parathyroid Glands and Prevent Hypoparathyroidism. 在全甲状腺切除术中使用吲哚青绿荧光识别甲状旁腺并预防甲状旁腺功能减退症
Q3 Medicine Pub Date : 2023-12-29 DOI: 10.52198/23.STI.43.GS1741
Daqi Zhang, Hui Sun, Francesco Frattini, Hoon Yub Kim, Che Wei Wu, Gianluca Donatini, Andrea Cestari, Simona Bertoli, Diego Barbieri, Mario Bussi, Gianlorenzo Dionigi

Introduction: Total thyroidectomy is associated with a high rate of transient or permanent hypoparathyroidism. During surgery, indocyanine green (ICG) fluorescein angiography can be used to detect and preserve well-vascularized parathyroid glands. This technique has been introduced as an intraoperative support to prevent postoperative hypoparathyroidism.

Material and methods: One-hundred consecutive patients who had undergone total thyroidectomy were included in this study. Autofluoroscopy was used on the first dominant side of thyroidectomy and to identify the contralateral parathyroid glands. An intravenous bolus of 5 mg ICG (VERDYE, Diagnostic Green GmbH, Aschheim-Dornacht, Germany) was administered once. ICG fluorescein angiography was used as a "bridge" at the end of the first dominant hemithyroidectomy and after exposure of the parathyroid glands on the second side. This allowed us to (i) determine the vascularization of the first two parathyroid glands and (ii) define the blood vessels and thus the line of dissection of the parathyroid glands of the second resection side. Finally, autofluoroscopy was then applied outside the surgical area on the surgical specimen to assess forgotten parathyroid glands, which should therefore be re-implanted. Autofluoroscopy and ICG fluorescein angiography were evaluated in real time using the same technology, i.e., FLUOBEAM® LX (EUROPE - Fluoptics Grenoble, France; USA - Fluoptics Imaging Inc., Cambridge, MA, USA). The study was approved by the local ethics committee.

Results: Autofluorescence and ICG fluorescein angiography were performed without any problems in all cases. A total of 370 parathyroid glands were detected in this series. ICG changed the surgical strategy for the first-side parathyroid glands in 5% of cases, i.e,. they were not well-vascularized and were re-implanted. The rate of transient hypoparathyroidism was 19%. The percentage of parathyroids in the surgical specimen was 3.5% and all were re-implanted during the same surgery. There was no case of postoperative definitive hypoparathyroidism when at least one parathyroid gland with a high fluorescence intensity was preserved on the first side of resection.

Conclusion: Use of ICG fluorescein angiography may contribute to predicting and thus preventing postoperative definitive hypoparathyroidism after total thyroidectomy. The results of this case series confirm recent studies. Caution is advised when weakly perfused parathyroid glands are discovered.

简介甲状腺全切除术会导致较高的一过性或永久性甲状旁腺功能减退。在手术过程中,吲哚菁绿(ICG)荧光素血管造影可用于检测和保留血管良好的甲状旁腺。这项技术已被引入作为术中辅助手段,以防止术后甲状旁腺功能减退:研究对象包括100名连续接受甲状腺全切除术的患者。在甲状腺切除术的第一显性侧使用自动荧光镜检查,并确定对侧甲状旁腺。一次静脉注射5毫克ICG(VERDYE,德国阿什海姆-多纳赫特诊断绿色有限公司)。ICG荧光素血管造影被用作第一个显性甲状旁腺切除术结束后和第二侧甲状旁腺暴露后的 "桥梁"。这样我们就能(i)确定前两个甲状旁腺的血管情况,(ii)确定血管,从而确定第二切除侧甲状旁腺的解剖线。最后,在手术区域外对手术标本进行自动荧光检查,以评估被遗忘的甲状旁腺,因此应将其重新植入。自体荧光镜检查和ICG荧光素血管造影使用相同的技术进行实时评估,即FLUOBEAM® LX(欧洲--法国格勒诺布尔Fluoptics公司;美国--美国马萨诸塞州剑桥Fluoptics成像公司)。该研究获得了当地伦理委员会的批准:结果:所有病例均顺利进行了自发荧光和ICG荧光素血管造影。该系列共检测出 370 个甲状旁腺。在5%的病例中,ICG改变了第一侧甲状旁腺的手术策略,即血管不通畅,需要重新植入。一过性甲状旁腺功能减退症的发生率为19%。手术标本中甲状旁腺的比例为3.5%,所有这些腺体都在同一次手术中被重新植入。如果在切除的第一侧至少保留了一个荧光强度较高的甲状旁腺,就不会出现术后明确的甲状旁腺功能减退症:结论:ICG荧光素血管造影有助于预测并预防甲状腺全切除术后明确的甲状旁腺功能减退症。本病例系列的结果证实了近期的研究。当发现甲状旁腺灌注不足时,应谨慎行事。
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引用次数: 0
Effect of Various Ancillary Operating Room Techniques on Wound Healing Outcomes After Total Knee Arthroplasty. 各种手术室辅助技术对全膝关节置换术后伤口愈合效果的影响
Q3 Medicine Pub Date : 2023-12-13 DOI: 10.52198/23.STI.43.OS1748
Jeremy A Dubin, Daniel Hameed, Sandeep S Bains, Tim Board, Ryan Nunley, Michael A Mont

Introduction: The successful management of wound healing after total knee arthroplasty (TKA) depends on several aspects of ancillary intraoperative techniques and surgical variables. Many of these have been evaluated in a few recent reports. The prior reviews studied many aspects of wound healing and, for example, found lower risks of wound complications with barbed sutures compared with interrupted closure with non-barbed sutures, no differences in wound complications between adhesives, subcuticular sutures, staples, glue, or mesh adhesives for the closure of the skin layer, and that mesh adhesives may be associated with faster closing times compared to subcuticular sutures or staples in TKA. However, some topics that can be influenced by the surgeon were not covered in these previous reviews. Namely, the use of deep vein thrombosis (DVT) prophylaxis, tourniquet application, management of intraoperative drains, surgical approach selection, and patellar handling techniques can all potentially influence wound healing. Therefore, in this comprehensive systematic review of the literature, we focused on these five factors that may influence wound healing. Specifically, we evaluated: (1) the impact of different DVT prophylaxis methods on wound healing and infection rates; (2) the role of tourniquet application on wound closure and potential infection risks; (3) the effects of intraoperative drain usage on wound healing; (4) the influence of different surgical approaches on wound closure and postoperative infection rates; and (5) the effects of varying patellar handling strategies on wound healing and infection rates.

Materials and methods: A systematic search of electronic databases, including PubMed, Cochrane Library, Medline, and Embase, was conducted to identify studies assessing auxiliary surgical techniques and their impact on wound healing in total knee arthroplasty (TKA). Relevant terms like "knee," "arthroplasty," and "wound healing" refined the search, which included English language publications until May 1, 2023. Independent screening by two authors and a third mediator facilitated the selection process, with 24 studies meeting the criteria. Assessment of these studies involved evaluating their evidence level and methodological quality using the Modified Coleman Methodology Score (MCMS). A comparison was made on wound healing outcomes in TKA, which included evaluating methodological quality parameters like sample sizes, follow-up durations, and clinical effect measurements. Data synthesis for the studies provided a comprehensive summary, categorizing them by evidence level.

Results: There were seven reports on DVT prophylaxis that showed no statistically significant differences in wound complications among various treatment methods and medications in patients undergoing total knee arthroplasty (TKA), with wound complication rates ranging from 0.25 to 1%, except that aspirin a

导言:全膝关节置换术(TKA)后伤口愈合的成功管理取决于术中辅助技术和手术变量的多个方面。最近的一些报告对其中的许多方面进行了评估。之前的综述对伤口愈合的许多方面进行了研究,例如,发现与使用无倒刺缝合线进行间断性闭合相比,使用有倒刺缝合线的伤口并发症风险较低;在闭合皮肤层时,粘合剂、皮下缝合线、订书钉、胶水或网状粘合剂之间的伤口并发症没有差异;在 TKA 中,与皮下缝合线或订书钉相比,网状粘合剂可能与更快的闭合时间有关。然而,在之前的这些综述中并没有涉及一些可能受外科医生影响的话题。也就是说,深静脉血栓(DVT)预防措施的使用、止血带的应用、术中引流管的管理、手术方式的选择以及髌骨处理技术都有可能影响伤口愈合。因此,在这篇全面系统的文献综述中,我们重点研究了这五个可能影响伤口愈合的因素。具体来说,我们评估了:(1) 不同的深静脉血栓预防方法对伤口愈合和感染率的影响;(2) 使用止血带对伤口愈合的作用和潜在的感染风险;(3) 术中使用引流管对伤口愈合的影响;(4) 不同手术方法对伤口愈合和术后感染率的影响;(5) 不同的髌骨处理策略对伤口愈合和感染率的影响:对电子数据库(包括 PubMed、Cochrane Library、Medline 和 Embase)进行了系统检索,以确定评估辅助手术技术及其对全膝关节置换术(TKA)伤口愈合影响的研究。膝关节"、"关节置换术 "和 "伤口愈合 "等相关术语完善了搜索范围,包括 2023 年 5 月 1 日之前的英文出版物。两位作者和第三位调解人进行了独立筛选,最终有 24 项研究符合标准。对这些研究的评估包括使用改良科尔曼方法评分法(MCMS)评估其证据水平和方法质量。对 TKA 的伤口愈合结果进行了比较,包括评估样本大小、随访时间和临床效果测量等方法学质量参数。研究数据综合提供了一份全面的摘要,并按证据等级进行了分类:有七项关于深静脉血栓预防的报告显示,在接受全膝关节置换术(TKA)的患者中,各种治疗方法和药物在伤口并发症方面没有统计学意义上的显著差异,伤口并发症发生率从0.25%到1%不等,但在最近的三项研究中,阿司匹林的伤口并发症发生率似乎低于其他方法。有五份关于使用止血带的报告显示伤口并发症的发生率普遍升高,但深部感染的发生率并没有升高。五份关于术中使用引流管的报告显示,虽然使用引流管组的总失血量从568毫升到1856毫升不等,而未使用引流管组的总失血量从119毫升到535毫升不等,但引流管组和未使用引流管组在伤口并发症、感染率或其他术后结果(如肿胀、深静脉血栓形成和活动范围)方面没有显著差异。有三项关于手术方法的研究显示,迷你髌下切口和髌骨内侧旁切口的伤口并发症发生率没有差异。此外,只有一份报告对髌骨外翻和胫骨前移的手术变量进行了研究:目前的文献强调了尽可能使用阿司匹林预防深静脉血栓形成的重要性,以及止血带可能导致浅表伤口并发症增加的可能性。引流管或手术方法似乎不会导致伤口问题。髌骨外翻和胫骨前移等手术变量需要更多研究。
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引用次数: 0
Efficacy of a 3D Electrospun Synthetic Polymer Matrix on Hard-to-Heal Wounds. 三维电纺合成聚合物基质对难愈合伤口的疗效
Q3 Medicine Pub Date : 2023-12-12 DOI: 10.52198/23.STI.43.WH1744
C Jake Lambert, Frank Aviles, Kristen A Eckert, Matthew Garoufalis, Richard A Schilling

Introduction: The aim of this study was to evaluate the efficacy of a 3D electrospun synthetic polymer matrix (3DESPM) on hard-to-heal wounds.

Materials and methods: This prospective case series took place at four sites. The primary endpoints were the percentage area reduction (PAR) in wound area at four and eight weeks. Secondary endpoints included time to heal (Kaplan-Meier analysis) and the proportion of healed wounds at 12 weeks. After applying 3DESPM, the physician applied sterile saline, as appropriate, to adhere the matrix to the wound bed and facilitate the polymer degradation process. A nonadherent dressing, a secondary dressing, and additional bandages (as needed) were then applied. The physician left the product on the wound until complete degradation was observed, as appropriate, and reapplied, as appropriate. Combination advanced therapies were applied, per physician discretion.

Results: Thirty-eight patients (mean age: 64.3 years [SD: 17.6]) with 50 wounds (35 chronic, 70%) participated. The mean number of comorbidities per patient was 4.4 (2.3). All wounds received 3DESPM; 12 wounds (24%) received combination therapies; and 38 wounds (76%) completed the study. The mean (SD) PAR at four and eight weeks was 67.6% (38%) and 80% (35%), respectively. Thirty-three wounds (66%) healed at 12 weeks. The Kaplan-Meier mean time to heal for all wounds was 49.0 days (95% confidence interval: 41.3-56.7).

Conclusions: In a complex patient population with severe comorbidities and heterogeneous wounds, 3DESPM appeared to accelerate the stalled healing process to contribute to wound closure. Further investigation of 3DESPM on a larger patient population and in a controlled setting is pending.

简介本研究旨在评估三维电纺合成聚合物基质(3DESPM)对难愈合伤口的疗效:这项前瞻性病例系列研究在四个地点进行。主要终点为四周和八周后伤口面积缩小百分比(PAR)。次要终点包括愈合时间(Kaplan-Meier 分析)和 12 周时愈合伤口的比例。涂抹 3DESPM 后,医生会根据情况涂抹无菌生理盐水,以将基质粘附在伤口床上,促进聚合物降解过程。然后使用非粘附性敷料、辅助敷料和额外的绷带(视需要而定)。医生视情况将产品留在伤口上,直到观察到完全降解为止,并视情况再次使用。根据医生的判断,采用综合先进疗法:38名患者(平均年龄:64.3岁[SD:17.6])共50处伤口(其中35处为慢性伤口,占70%)参与了此次研究。每位患者的平均合并症数量为 4.4(2.3)个。所有伤口都接受了 3DESPM 治疗;12 个伤口(24%)接受了综合疗法;38 个伤口(76%)完成了研究。4周和8周时的平均(标清)PAR 分别为67.6%(38%)和80%(35%)。33处伤口(66%)在12周时愈合。所有伤口的 Kaplan-Meier 平均愈合时间为 49.0 天(95% 置信区间:41.3-56.7):结论:在具有严重并发症和不同伤口的复杂患者群体中,3DESPM 似乎能加速停滞的愈合过程,促进伤口闭合。在更大的患者群体和对照环境中对 3DESPM 的进一步研究还在进行中。
{"title":"Efficacy of a 3D Electrospun Synthetic Polymer Matrix on Hard-to-Heal Wounds.","authors":"C Jake Lambert, Frank Aviles, Kristen A Eckert, Matthew Garoufalis, Richard A Schilling","doi":"10.52198/23.STI.43.WH1744","DOIUrl":"10.52198/23.STI.43.WH1744","url":null,"abstract":"<p><strong>Introduction: </strong>The aim of this study was to evaluate the efficacy of a 3D electrospun synthetic polymer matrix (3DESPM) on hard-to-heal wounds.</p><p><strong>Materials and methods: </strong>This prospective case series took place at four sites. The primary endpoints were the percentage area reduction (PAR) in wound area at four and eight weeks. Secondary endpoints included time to heal (Kaplan-Meier analysis) and the proportion of healed wounds at 12 weeks. After applying 3DESPM, the physician applied sterile saline, as appropriate, to adhere the matrix to the wound bed and facilitate the polymer degradation process. A nonadherent dressing, a secondary dressing, and additional bandages (as needed) were then applied. The physician left the product on the wound until complete degradation was observed, as appropriate, and reapplied, as appropriate. Combination advanced therapies were applied, per physician discretion.</p><p><strong>Results: </strong>Thirty-eight patients (mean age: 64.3 years [SD: 17.6]) with 50 wounds (35 chronic, 70%) participated. The mean number of comorbidities per patient was 4.4 (2.3). All wounds received 3DESPM; 12 wounds (24%) received combination therapies; and 38 wounds (76%) completed the study. The mean (SD) PAR at four and eight weeks was 67.6% (38%) and 80% (35%), respectively. Thirty-three wounds (66%) healed at 12 weeks. The Kaplan-Meier mean time to heal for all wounds was 49.0 days (95% confidence interval: 41.3-56.7).</p><p><strong>Conclusions: </strong>In a complex patient population with severe comorbidities and heterogeneous wounds, 3DESPM appeared to accelerate the stalled healing process to contribute to wound closure. Further investigation of 3DESPM on a larger patient population and in a controlled setting is pending.</p>","PeriodicalId":22194,"journal":{"name":"Surgical technology international","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138810982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Novel Use of Bipolar Radiofrequency Microneedling in the Treatment of Lichen Sclerosus. 双极射频微针治疗硬化地衣的新应用。
Q3 Medicine Pub Date : 2023-12-01 DOI: 10.52198/23.STI.43.GY1743
Tracy A Blusewicz, Katherine P Coley, Robert D Moore, John R Miklos

Introduction: Lichen sclerosus (LS) is a chronic, distressing, inflammatory process that has a huge impact on quality of life in women. Uncontrolled vulvar LS can lead to chronic symptoms of itching and pain and can lead to anatomic changes, scarring, and elevated risk of cancer. First-line therapy with corticosteroids is often not successful in controlling symptoms, especially over the long term. This is the first study to review the effects of bipolar radiofrequency (RF) with microneedling to treat the vaginal and vulvar symptoms of LS.

Materials and methods: This retrospective study was initiated due to the recognition of improvement in vulvar skin condition and resolution of lichen sclerosus symptoms in patients who had already failed traditional treatment and underwent radio frequency with microneedling procedures of the vulva, perineum, and perianal regions. Patients were treated with three treatments of bipolar RF and bipolar RF with microneedling four to eight weeks apart. Patient questionnaires were used to assess improvement in the symptoms of LS including itching, tearing of tissue, changes in the appearance and color of tissue, and dryness of skin and mucosa.

Results: The data from the questionnaires showed a significant reduction or complete resolution in these symptoms, with 86% of the patients reporting either significant or complete resolution. In the case of itching, which is typically one of the most severe symptoms of LS, 91% of patients reported significant or complete resolution. 87% of patients reported symptom resolution lasting at least six months, with 39% of the patients having results lasting 12 months or more before recurrence. Recurrences can be retreated on an as-needed basis or with annual maintenance therapy consisting typically of just one treatment.

Conclusion: Radiofrequency with microneedling treatments for persistent LS showed significant improvement in LS symptoms. As LS is a chronic recurring condition, the treatment protocol resulted in high patient satisfaction for these women who had not experienced these results in terms of amount of symptom resolution or duration of symptom resolution with prior treatments using topical steroid cream or other modalities.

简介:硬化地衣(LS)是一种慢性、痛苦的炎症过程,对女性的生活质量有巨大的影响。不受控制的外阴LS可导致瘙痒和疼痛的慢性症状,并可导致解剖变化,疤痕和癌症风险增加。使用皮质类固醇的一线治疗通常不能成功控制症状,特别是长期治疗。这是第一个回顾双极射频(RF)微针治疗LS阴道和外阴症状效果的研究。材料和方法:由于认识到传统治疗失败的患者在外阴、会阴和肛周区域进行射频微针手术后外阴皮肤状况改善和硬化地衣症状缓解,因此开展了本回顾性研究。患者接受双极射频和双极射频三种治疗,间隔4至8周进行微针治疗。使用患者问卷来评估LS症状的改善情况,包括瘙痒、组织撕裂、组织外观和颜色的变化以及皮肤和粘膜的干燥。结果:问卷调查的数据显示这些症状显著减轻或完全缓解,86%的患者报告显着或完全缓解。瘙痒通常是LS最严重的症状之一,91%的患者报告明显或完全缓解。87%的患者报告症状缓解持续至少6个月,39%的患者在复发前症状缓解持续12个月或更长时间。复发可以根据需要进行治疗,也可以每年进行一次维持治疗。结论:射频微针治疗持续性肌萎缩性侧索硬化症可显著改善肌萎缩性侧索硬化症症状。由于LS是一种慢性复发性疾病,治疗方案使这些妇女在症状缓解的数量或症状缓解的持续时间方面获得了很高的满意度,这些妇女之前使用局部类固醇乳膏或其他方式治疗时没有经历过这些结果。
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引用次数: 0
3D Reconstruction for a Complex Pediatric Redo Aortic Arch Surgery in a 9-Year-Old Ukrainian Refugee. 一名9岁乌克兰难民复杂的儿童重做主动脉弓手术的3D重建。
Q3 Medicine Pub Date : 2023-11-30 DOI: 10.52198/23.STI.43.CV1738
Luigi Garufi, Alvise Guariento, Francesco Bertelli, Vladimiro Vida

Redo aortic surgery poses significant challenges, particularly in complex scenarios involving congenital heart conditions that have been previously operated on several years prior. The integration of three-dimensional (3D) reconstruction and printing holds immense potential to greatly improve surgical precision, particularly in critical situations.

重做主动脉手术面临着巨大的挑战,特别是在涉及先天性心脏病的复杂情况下,这些先天性心脏病已经在几年前进行过手术。三维(3D)重建和打印的整合具有巨大的潜力,可以大大提高手术精度,特别是在危急情况下。
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引用次数: 0
期刊
Surgical technology international
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