D. Šegan, Saša Štupar, M. Kalanj, Natalija Pantelic, M. Pejović-Milovančević
Introduction/Objective. COVID-19 pandemic caused many disruptions in the daily routines of children and adolescents, which might have influenced their mental health. This study aimed to examine the impact of the COVID-19 pandemic on self-harming behaviors, including non-suicidal self-injury (NSSI) and suicide attempts in children and youth seeking psychiatric help. Methods. Retrospective, cross-sectional study was conducted, analyzing data from medical documentation of 1129 outpatients, aged between 10 and 18, who had their first psychiatric examination in the Institute of Mental Health in Belgrade, Serbia between March 1st 2019 and August 31st 2021. Frequency of NSSI and suicide attempt during the pandemic was compared to a one-year period before the pandemic. Results. Proportions of patients with NSSI were higher in both years during the pandemic (18.1%; 27.7%) compared to the year before (12.6%), especially in the second year of the pandemic, with a marked increase in March 2021. NSSI was more frequent in girls, older adolescents, those living in incomplete families and those with a history of abuse. No significant change in the frequency of suicide attempts related to the COVID-19 pandemic was found. Conclusion. Significant increase in the frequency of NSSI, markedly during the second year of the pandemic, especially in children and youth with additional factors of vulnerability, calls for further attention from both professionals and policymakers, as well as preventive measures for this vulnerable group during stressful times.
{"title":"Self-harm in children and youth - impact of the COVID-19 pandemic","authors":"D. Šegan, Saša Štupar, M. Kalanj, Natalija Pantelic, M. Pejović-Milovančević","doi":"10.2298/sarh230128045s","DOIUrl":"https://doi.org/10.2298/sarh230128045s","url":null,"abstract":"Introduction/Objective. COVID-19 pandemic caused many disruptions in the daily routines of children and adolescents, which might have influenced their mental health. This study aimed to examine the impact of the COVID-19 pandemic on self-harming behaviors, including non-suicidal self-injury (NSSI) and suicide attempts in children and youth seeking psychiatric help. Methods. Retrospective, cross-sectional study was conducted, analyzing data from medical documentation of 1129 outpatients, aged between 10 and 18, who had their first psychiatric examination in the Institute of Mental Health in Belgrade, Serbia between March 1st 2019 and August 31st 2021. Frequency of NSSI and suicide attempt during the pandemic was compared to a one-year period before the pandemic. Results. Proportions of patients with NSSI were higher in both years during the pandemic (18.1%; 27.7%) compared to the year before (12.6%), especially in the second year of the pandemic, with a marked increase in March 2021. NSSI was more frequent in girls, older adolescents, those living in incomplete families and those with a history of abuse. No significant change in the frequency of suicide attempts related to the COVID-19 pandemic was found. Conclusion. Significant increase in the frequency of NSSI, markedly during the second year of the pandemic, especially in children and youth with additional factors of vulnerability, calls for further attention from both professionals and policymakers, as well as preventive measures for this vulnerable group during stressful times.","PeriodicalId":22263,"journal":{"name":"Srpski arhiv za celokupno lekarstvo","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68731362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction/Objective. The study estimates the associations between the key pandemic indicators and the allocation of COVID-19 related bonus and welfare payments to Russian health care workers. The aim was to estimate the association between the key pandemic indicators and the allocation of the COVID-19 related bonus and welfare payments to Russian health workers. Methods. The study uses regression analysis. Results. The study examines two consecutive types of COVID-19 related bonus payments: (1) incentive payments (in 2020) and (2) welfare payments (in 2020-2022). Concerning incentive payments (type 1), the study supports hypotheses regarding the association between the number of persons infected with COVID-19 in a relevant region and the actual/estimated amount of budget transfers to a relevant region for bonus payments to medical workers (a) for special working conditions and additional workload and (b) for performing particularly important work. As for welfare payments (type 2), the study supports hypotheses regarding the association between (1) COVID-19 cases, (2) COVID-19 recoveries, and (3) the fiscal year close-out and the amount of welfare payments. Conclusion. The main channel for financing payments to medical workers is a special welfare payment through the system of the Social Insurance Fund of the Russian Federation. This source exceeds the estimated total transfers and subsidies for similar purposes in 2020. The study tests hypotheses regarding the association between the key pandemic indicators and the size of various types of budget transfers for bonus and welfare payments to medical workers.
{"title":"COVID-related incentive payments to health care workers","authors":"I. Bocharova, A. Rymanov","doi":"10.2298/sarh221221022b","DOIUrl":"https://doi.org/10.2298/sarh221221022b","url":null,"abstract":"Introduction/Objective. The study estimates the associations between the key pandemic indicators and the allocation of COVID-19 related bonus and welfare payments to Russian health care workers. The aim was to estimate the association between the key pandemic indicators and the allocation of the COVID-19 related bonus and welfare payments to Russian health workers. Methods. The study uses regression analysis. Results. The study examines two consecutive types of COVID-19 related bonus payments: (1) incentive payments (in 2020) and (2) welfare payments (in 2020-2022). Concerning incentive payments (type 1), the study supports hypotheses regarding the association between the number of persons infected with COVID-19 in a relevant region and the actual/estimated amount of budget transfers to a relevant region for bonus payments to medical workers (a) for special working conditions and additional workload and (b) for performing particularly important work. As for welfare payments (type 2), the study supports hypotheses regarding the association between (1) COVID-19 cases, (2) COVID-19 recoveries, and (3) the fiscal year close-out and the amount of welfare payments. Conclusion. The main channel for financing payments to medical workers is a special welfare payment through the system of the Social Insurance Fund of the Russian Federation. This source exceeds the estimated total transfers and subsidies for similar purposes in 2020. The study tests hypotheses regarding the association between the key pandemic indicators and the size of various types of budget transfers for bonus and welfare payments to medical workers.","PeriodicalId":22263,"journal":{"name":"Srpski arhiv za celokupno lekarstvo","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68731381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jelena Ilić-Živojinović, Tanja Mitic, Marijana Sreckovic, D. Backović, I. Soldatovic
Introduction/Objective Problematic internet use has been associated with various mental health problems. The objective of this study was to investigate the internet use and its relationship with depressive symptoms among high school students. Methods This cross-sectional observational study included 620 students from the first to the fourth grade of four high schools in Pozarevac. The research data were obtained from an ad hoc designed questionnaire on socio-demographic data, health habits and the internet use, Internet Addiction Test (IAT) and Center for Epidemiological Studies Depression Scale for Children (CES-DC). Results Out of 620 students (66.9% girls) there were 389 respondents (62.7%) who reported normal (n = 40), or average internet use (n = 349) with a mild level of addiction, while 226 (36.5%) subjects belonged to problematic internet use group, and 5 students (0.8%) showed a high level of internet addiction. A CES-DC score ? 15, considered indicative of clinically significant depressive symptoms, was found significantly more frequent among internet addicts compared to internet normal users (78.4% vs. 46.5%, respectively). Among internet addicts there was a significantly higher percentage of those who used psychologist/psychotherapist help compared to internet normal users (29.4% vs. 12.1%, respectively). The logistic regression analysis showed that Internet Addiction (IAT score ? 50) was the strongest independent predictor of clinically significant depressive symptoms (OR = 3.32; 95% CI = 2.24-4.91), after adjusting for confounders (female gender, urban living, Tik Tok and Twitter use, sports activities, and use of the internet for learning or for aimless "surfing?). Conclusion We show that internet addiction is positively related to clinically significant depressive symptoms among high school students. Health education focused on the proper use of the internet may be regarded as mental health promotion.
{"title":"The relationship between internet use and depressive symptoms among high school students","authors":"Jelena Ilić-Živojinović, Tanja Mitic, Marijana Sreckovic, D. Backović, I. Soldatovic","doi":"10.2298/sarh230104050i","DOIUrl":"https://doi.org/10.2298/sarh230104050i","url":null,"abstract":"Introduction/Objective Problematic internet use has been associated with various mental health problems. The objective of this study was to investigate the internet use and its relationship with depressive symptoms among high school students. Methods This cross-sectional observational study included 620 students from the first to the fourth grade of four high schools in Pozarevac. The research data were obtained from an ad hoc designed questionnaire on socio-demographic data, health habits and the internet use, Internet Addiction Test (IAT) and Center for Epidemiological Studies Depression Scale for Children (CES-DC). Results Out of 620 students (66.9% girls) there were 389 respondents (62.7%) who reported normal (n = 40), or average internet use (n = 349) with a mild level of addiction, while 226 (36.5%) subjects belonged to problematic internet use group, and 5 students (0.8%) showed a high level of internet addiction. A CES-DC score ? 15, considered indicative of clinically significant depressive symptoms, was found significantly more frequent among internet addicts compared to internet normal users (78.4% vs. 46.5%, respectively). Among internet addicts there was a significantly higher percentage of those who used psychologist/psychotherapist help compared to internet normal users (29.4% vs. 12.1%, respectively). The logistic regression analysis showed that Internet Addiction (IAT score ? 50) was the strongest independent predictor of clinically significant depressive symptoms (OR = 3.32; 95% CI = 2.24-4.91), after adjusting for confounders (female gender, urban living, Tik Tok and Twitter use, sports activities, and use of the internet for learning or for aimless \"surfing?). Conclusion We show that internet addiction is positively related to clinically significant depressive symptoms among high school students. Health education focused on the proper use of the internet may be regarded as mental health promotion.","PeriodicalId":22263,"journal":{"name":"Srpski arhiv za celokupno lekarstvo","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68731608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gordana Ristovska, N. Manusheva, B. Aleksovski, Jansun Bukovetz, Vera Stojanovska, Z. Babinkostova
Introduction/Objective In the first year of COVID-19 pandemic, global prevalence of anxiety and depression increased by a massive 25%, according to the World Health Organization. Objective of the study was to determine the level of depression and insomnia among students in North Macedonia during COVID-19 pandemic. Methods Cross-sectional study was performed among students at the Ss. Cyril and Methodius University in Skopje during May-July of 2021. The anonymous online survey contained questions for sex, age, their opinion, and attitude to COVID-19 infection, if they had any infection/isolation and about physical activity during the pandemic. We used scales for assessment of insomnia (Insomnia Severity Index - ISI) and depression (Patient Health Questionnaire 9 - PHQ-9). Results The study was completed by 355 participants, 28.4% of them had clinically important insomnia scores and almost 47.5% of the participants presented clinically important depression scores. Female and younger participants had higher scores for both scales. A highly statistically significant, positive correlation was detected between ISI and PHQ-9 scores (? = 0.646, p = 4.05?10-43), suggesting that during the examined cross-sectional period of COVID-19 pandemics, depression and insomnia were mutually connected. Conclusions COVID-19 pandemic caused a serious impact on mental health of the population, especially on young people, girls, students, and those who live alone. Therefore, we should be prepared for support and treatment of these vulnerable groups, not only as health care services, but also as educational institutions to give support to students in terms of consultation and motivation.
{"title":"Depression and insomnia among students during COVID-19 pandemic - cross sectional study","authors":"Gordana Ristovska, N. Manusheva, B. Aleksovski, Jansun Bukovetz, Vera Stojanovska, Z. Babinkostova","doi":"10.2298/sarh230324052r","DOIUrl":"https://doi.org/10.2298/sarh230324052r","url":null,"abstract":"Introduction/Objective In the first year of COVID-19 pandemic, global prevalence of anxiety and depression increased by a massive 25%, according to the World Health Organization. Objective of the study was to determine the level of depression and insomnia among students in North Macedonia during COVID-19 pandemic. Methods Cross-sectional study was performed among students at the Ss. Cyril and Methodius University in Skopje during May-July of 2021. The anonymous online survey contained questions for sex, age, their opinion, and attitude to COVID-19 infection, if they had any infection/isolation and about physical activity during the pandemic. We used scales for assessment of insomnia (Insomnia Severity Index - ISI) and depression (Patient Health Questionnaire 9 - PHQ-9). Results The study was completed by 355 participants, 28.4% of them had clinically important insomnia scores and almost 47.5% of the participants presented clinically important depression scores. Female and younger participants had higher scores for both scales. A highly statistically significant, positive correlation was detected between ISI and PHQ-9 scores (? = 0.646, p = 4.05?10-43), suggesting that during the examined cross-sectional period of COVID-19 pandemics, depression and insomnia were mutually connected. Conclusions COVID-19 pandemic caused a serious impact on mental health of the population, especially on young people, girls, students, and those who live alone. Therefore, we should be prepared for support and treatment of these vulnerable groups, not only as health care services, but also as educational institutions to give support to students in terms of consultation and motivation.","PeriodicalId":22263,"journal":{"name":"Srpski arhiv za celokupno lekarstvo","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68732360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katarina Bačulov, M. Djan, B. Bajkin, Ivana Mijatov, N. Vuckovic, Saša Mijatov, I. Djan, I. Barjaktarović, Jelena Stojčević-Maletić, N. Vučinić
Introduction/Objective. Genetic aberrations and environmental factors are known to play an important role in oral squamous cell carcinoma (OSCC). The aim of the study was to clarify the association of epidermal growth factor receptor (EGFR) gene polymorphism rs1468727 with overall survival (OS) in patients with OSCC. Methods. The study comprised a total of sixty-one patients diagnosed with OSCC. The follow-up period for each patient was 3 years from the date of surgery and during that period their genotypes for rs1468727 polymorphism of the EGFR gene were identified using Real-Time PCR. Binary logistic regression was used to investigate the influence of various variables on survival. Additionally, the Chi-square test of independence and Man-Whitney U test were done to examine the interplay between two categorical variables and two independent samples. Results. Two variables demonstrated a statistically significant influence on OS: the TNM Classification (TNM) stage and EGFR genotype. At the end of the follow-up period, 39 patients survived, with a noteworthy observation that more than half of the survivors had the EGFR rs1468727 CC genotype. The distribution of CC and CT genotypes was equal (chi-square = 0.397, df = 2 p = 0.820) among patients who deceased indicating that no statistically significant correlations were found between OS and demographic or tumor-related characteristics. Conclusion. EGFR rs1468727 homozygote (genotype CC) and TNM stage showed statistically significant influence on OS in the follow-up period. This study highlights the potential significance of homozygote EGFR rs1468727 CC in assessing the prognosis and treatment outcomes of patients undergoing surgery for OSCC.
{"title":"Impact of epidermal growth factor receptor gene RS1468727 polymorphism on survival of the patients with oral squamous cell carcinoma","authors":"Katarina Bačulov, M. Djan, B. Bajkin, Ivana Mijatov, N. Vuckovic, Saša Mijatov, I. Djan, I. Barjaktarović, Jelena Stojčević-Maletić, N. Vučinić","doi":"10.2298/sarh230306076b","DOIUrl":"https://doi.org/10.2298/sarh230306076b","url":null,"abstract":"Introduction/Objective. Genetic aberrations and environmental factors are known to play an important role in oral squamous cell carcinoma (OSCC). The aim of the study was to clarify the association of epidermal growth factor receptor (EGFR) gene polymorphism rs1468727 with overall survival (OS) in patients with OSCC. Methods. The study comprised a total of sixty-one patients diagnosed with OSCC. The follow-up period for each patient was 3 years from the date of surgery and during that period their genotypes for rs1468727 polymorphism of the EGFR gene were identified using Real-Time PCR. Binary logistic regression was used to investigate the influence of various variables on survival. Additionally, the Chi-square test of independence and Man-Whitney U test were done to examine the interplay between two categorical variables and two independent samples. Results. Two variables demonstrated a statistically significant influence on OS: the TNM Classification (TNM) stage and EGFR genotype. At the end of the follow-up period, 39 patients survived, with a noteworthy observation that more than half of the survivors had the EGFR rs1468727 CC genotype. The distribution of CC and CT genotypes was equal (chi-square = 0.397, df = 2 p = 0.820) among patients who deceased indicating that no statistically significant correlations were found between OS and demographic or tumor-related characteristics. Conclusion. EGFR rs1468727 homozygote (genotype CC) and TNM stage showed statistically significant influence on OS in the follow-up period. This study highlights the potential significance of homozygote EGFR rs1468727 CC in assessing the prognosis and treatment outcomes of patients undergoing surgery for OSCC.","PeriodicalId":22263,"journal":{"name":"Srpski arhiv za celokupno lekarstvo","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68732654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Krusic, N. Pejcic, Mirjana Stojanovic-Tasic, D. Damnjanovic, G. Abir
Introduction Improved outcomes after liver transplantation contribute to a successful pregnancy and delivery in transplant recipients. Anesthesiology teams face challenges when providing perioperative care to patients who have a liver transplant and undergo cesarean delivery, which include: an increased rate of cesarean delivery, a high risk of infection, and a high risk of interaction between immunosuppressant and anesthetic drugs. Case outline We report the case of a 28-year-old patient with a liver transplant (from a live donor) who underwent elective cesarean delivery under neuraxial anesthesia. Appropriate anesthetic management is critical to ensure optimal perioperative maternal and fetal outcomes. Cardiovascular stability after neuraxial anesthesia was maintained with adequate perioperative intravenous fluid management and early vasopressor(s) administration to preserve hepatic perfusion. Multimodal postoperative analgesia was administered; however, caution is required when prescribing drugs that have the potential for hepatic and renal side effects. Conclusion Multidisciplinary team evaluation, planning, and preparation are vital for optimizing safe care and delivery of pregnant patients with transplanted organs.
{"title":"Cesarean delivery under neuraxial anesthesia in a patient with a liver transplant","authors":"S. Krusic, N. Pejcic, Mirjana Stojanovic-Tasic, D. Damnjanovic, G. Abir","doi":"10.2298/sarh221108056k","DOIUrl":"https://doi.org/10.2298/sarh221108056k","url":null,"abstract":"Introduction Improved outcomes after liver transplantation contribute to a successful pregnancy and delivery in transplant recipients. Anesthesiology teams face challenges when providing perioperative care to patients who have a liver transplant and undergo cesarean delivery, which include: an increased rate of cesarean delivery, a high risk of infection, and a high risk of interaction between immunosuppressant and anesthetic drugs. Case outline We report the case of a 28-year-old patient with a liver transplant (from a live donor) who underwent elective cesarean delivery under neuraxial anesthesia. Appropriate anesthetic management is critical to ensure optimal perioperative maternal and fetal outcomes. Cardiovascular stability after neuraxial anesthesia was maintained with adequate perioperative intravenous fluid management and early vasopressor(s) administration to preserve hepatic perfusion. Multimodal postoperative analgesia was administered; however, caution is required when prescribing drugs that have the potential for hepatic and renal side effects. Conclusion Multidisciplinary team evaluation, planning, and preparation are vital for optimizing safe care and delivery of pregnant patients with transplanted organs.","PeriodicalId":22263,"journal":{"name":"Srpski arhiv za celokupno lekarstvo","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68729840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jelena Stojčević-Maletić, I. Barjaktarović, Katarina Bačulov, V. Čabarkapa, V. Sakač, Z. Gojković
Introduction/Objective. Based on the World Health Organization guidelines, the current "gold standard" to diagnose Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is reverse transcription-quantitative real-time polymerase chain reaction (RT-qPCR). The objective of this study was to compare and analyze the detection performance of two different authorized SARS-CoV-2 nucleic acid detection assays: the Abbott RealTime SARS-CoV-2 (ACOV) assay and the BGI Real-Time Fluorescent RT-PCR (BGI) kit. Methods. Our study included 384 randomly selected nasopharyngeal and oropharyngeal swabs previously tested by the ACOV and subsequently tested by the BGI kit for detecting SARS-CoV-2. All patients were adult individuals with symptoms or suspected of Coronavirus disease 2019 (COVID-19). Results. We found that the ACOV assay detected more cases of COVID-19 infection than the BGI assay. The positive percent agreement was 98.3% (95% confidence intervals (95% CI): 95.7-99.3%), while Cohen?s Kappa coefficient (Kappa) was 0.86 (95% CI: 0.80-0.91), indicating a strong level of agreement between these two tests. The negative percent agreement was 85.1% (95% CI: 78.3-90%), while 5.47% of cases were false negative using the BGI test to detect SARS-CoV-2. The sensitivity of the BGI test compared to Abbott was 91.73% (95% CI: 87.64-94.81%), and the specificity of the BGI test was 96.77% (95% CI: 91.95-99.11%). Conclusion. The Abbott kit showed a bit better diagnostic performance, and due to possible false negative results using the BGI test, we recommend complete testing with the ACOV test.
{"title":"Comparison of diagnostic efficacy of the Abbott RealTime SARS-CoV-2 assay and the BGI real-time fluorescent RT-PCR kit for the RT-PCR-based detection of Severe Acute Respiratory Syndrome Coronavirus-2","authors":"Jelena Stojčević-Maletić, I. Barjaktarović, Katarina Bačulov, V. Čabarkapa, V. Sakač, Z. Gojković","doi":"10.2298/sarh230201074s","DOIUrl":"https://doi.org/10.2298/sarh230201074s","url":null,"abstract":"Introduction/Objective. Based on the World Health Organization guidelines, the current \"gold standard\" to diagnose Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is reverse transcription-quantitative real-time polymerase chain reaction (RT-qPCR). The objective of this study was to compare and analyze the detection performance of two different authorized SARS-CoV-2 nucleic acid detection assays: the Abbott RealTime SARS-CoV-2 (ACOV) assay and the BGI Real-Time Fluorescent RT-PCR (BGI) kit. Methods. Our study included 384 randomly selected nasopharyngeal and oropharyngeal swabs previously tested by the ACOV and subsequently tested by the BGI kit for detecting SARS-CoV-2. All patients were adult individuals with symptoms or suspected of Coronavirus disease 2019 (COVID-19). Results. We found that the ACOV assay detected more cases of COVID-19 infection than the BGI assay. The positive percent agreement was 98.3% (95% confidence intervals (95% CI): 95.7-99.3%), while Cohen?s Kappa coefficient (Kappa) was 0.86 (95% CI: 0.80-0.91), indicating a strong level of agreement between these two tests. The negative percent agreement was 85.1% (95% CI: 78.3-90%), while 5.47% of cases were false negative using the BGI test to detect SARS-CoV-2. The sensitivity of the BGI test compared to Abbott was 91.73% (95% CI: 87.64-94.81%), and the specificity of the BGI test was 96.77% (95% CI: 91.95-99.11%). Conclusion. The Abbott kit showed a bit better diagnostic performance, and due to possible false negative results using the BGI test, we recommend complete testing with the ACOV test.","PeriodicalId":22263,"journal":{"name":"Srpski arhiv za celokupno lekarstvo","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68731908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction Leiomyosarcoma (LMS) of the inferior vena cava (IVC) is a rare mesenchymal tumor originating from the endothelial smooth muscle of the intima and account for about 1-2% of all the sarcomas of the soft tissue. The objective of this article is to show a case of IVC leiomyosarcoma, it?s resection and reconstruction using ProxiCor. Case outlines We showed a case of a 65-year-old woman presented with abdominal pain and mass in subhepatic space, who underwent surgery and resection of a leiomyosarcoma of IVC. IVC was reconstructed with ProxiCor patch, and patohistology confirmed that it was leiomyosarcoma. Conclusion Our experience has shown that the application of extracellular matrix (ECM) is safe and has given a satisfactory treatment result. A comparison with a much larger number of patients will give a true picture of the advantages and disadvantages of this type of material in vascular reconstructive procedures.
{"title":"Resection of inferior vena cava leiomyosarcoma and reconstruction using ProxiCor patch","authors":"A. Karamarkovic, Vladica Cuk, J. Juloski","doi":"10.2298/sarh230206069k","DOIUrl":"https://doi.org/10.2298/sarh230206069k","url":null,"abstract":"Introduction Leiomyosarcoma (LMS) of the inferior vena cava (IVC) is a rare mesenchymal tumor originating from the endothelial smooth muscle of the intima and account for about 1-2% of all the sarcomas of the soft tissue. The objective of this article is to show a case of IVC leiomyosarcoma, it?s resection and reconstruction using ProxiCor. Case outlines We showed a case of a 65-year-old woman presented with abdominal pain and mass in subhepatic space, who underwent surgery and resection of a leiomyosarcoma of IVC. IVC was reconstructed with ProxiCor patch, and patohistology confirmed that it was leiomyosarcoma. Conclusion Our experience has shown that the application of extracellular matrix (ECM) is safe and has given a satisfactory treatment result. A comparison with a much larger number of patients will give a true picture of the advantages and disadvantages of this type of material in vascular reconstructive procedures.","PeriodicalId":22263,"journal":{"name":"Srpski arhiv za celokupno lekarstvo","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68732471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Džemail Detanac, Kemal Brnicanin, Dzenana A. Detanac, Enes Zogic, Sead Marovac
Introduction. In healthy adults, accidental ingestion of foreign bodies is uncommon. Intestinal perforation by ingested bone fragments is rare, but can be presented as life-threatening condition, especially when the diagnosis is delayed. Case outline. We present an uncommon case of a 73-year-old female with acute abdominal symptoms due to ileal perforation caused by accidental ingested animal bone. Pneumoperitoneum revealed by abdominal X-ray and abdominal free fluid revealed by abdominal ultrasound as well as the general condition of the patient required an urgent laparotomy, when the diagnosis of ileal perforation was made. A foreign body was removed from the intestine, along with partial resection of the intestine and end-to-end anastomosis. Conclusion. Surgical treatment of life-threatening complications arising after ingestion of foreign bodies is the only method of choice in the treatment of such patients.
{"title":"Ileal perforation by accidentally ingested animal bone - rare cause of acute abdomen","authors":"Džemail Detanac, Kemal Brnicanin, Dzenana A. Detanac, Enes Zogic, Sead Marovac","doi":"10.2298/sarh221119018d","DOIUrl":"https://doi.org/10.2298/sarh221119018d","url":null,"abstract":"Introduction. In healthy adults, accidental ingestion of foreign bodies is uncommon. Intestinal perforation by ingested bone fragments is rare, but can be presented as life-threatening condition, especially when the diagnosis is delayed. Case outline. We present an uncommon case of a 73-year-old female with acute abdominal symptoms due to ileal perforation caused by accidental ingested animal bone. Pneumoperitoneum revealed by abdominal X-ray and abdominal free fluid revealed by abdominal ultrasound as well as the general condition of the patient required an urgent laparotomy, when the diagnosis of ileal perforation was made. A foreign body was removed from the intestine, along with partial resection of the intestine and end-to-end anastomosis. Conclusion. Surgical treatment of life-threatening complications arising after ingestion of foreign bodies is the only method of choice in the treatment of such patients.","PeriodicalId":22263,"journal":{"name":"Srpski arhiv za celokupno lekarstvo","volume":"132 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68730044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marija Simonovic, Marko Slavković, M. Mirić, D. Erić
Introduction/Objective. Professional burnout has sparked academic interest as one of the phenomena with the most serious implications for healthcare employees? well-being. As burnout becomes an increasingly common issue in medical practice, more extensive research on its predictors is needed. This study aimed to examine whether and how job satisfaction and work-related burnout affect personal burnout. Methods. A structured questionnaire was used to collect primary data. The sample consists of 218 employees from transfusion medicine units located in five cities in the central part of Serbia. Descriptive statistical analysis, correlation, and hierarchical regression were applied. Results. We found the personal burnout is negatively affected by job satisfaction, predominantly by working conditions (? = -0,141, t = -2,780, p < 0.01), and positively impacted to work-related burnout (? = 0,690, t = 13,409, p < 0.001) indicated that workload has strong impact on personal life quality of healthcare professionals employed in blood banks. Conclusion. This research contributes to more comprehensive understanding of personal burnout factors. The findings of this study can be used to develop strategies to promote employee well-being and prevent burnout in different manifestations.
介绍/目标。职业倦怠作为对医护人员影响最严重的现象之一，引起了学术界的兴趣。幸福。随着职业倦怠在医疗实践中越来越普遍，需要对其预测因素进行更广泛的研究。本研究旨在探讨工作满意度和工作倦怠对个人职业倦怠的影响。方法。采用结构化问卷收集原始数据。样本包括来自位于塞尔维亚中部五个城市的输血医学单位的218名雇员。采用描述性统计分析、相关分析和层次回归分析。结果。我们发现个人倦怠受工作满意度的负向影响，主要受工作条件(?= -0,141, t = -2,780, p < 0.01)，对工作倦怠有正向影响(?= 0.690, t = 13409, p < 0.001)表明工作量对血库医务人员个人生活质量有较大影响。结论。本研究有助于更全面地了解个人倦怠的影响因素。本研究结果可用于制定促进员工幸福感和预防不同表现形式的职业倦怠的策略。
{"title":"Relationship between work-related outcomes of healthcare professionals in transfusion medicine units","authors":"Marija Simonovic, Marko Slavković, M. Mirić, D. Erić","doi":"10.2298/sarh221220025s","DOIUrl":"https://doi.org/10.2298/sarh221220025s","url":null,"abstract":"Introduction/Objective. Professional burnout has sparked academic interest as one of the phenomena with the most serious implications for healthcare employees? well-being. As burnout becomes an increasingly common issue in medical practice, more extensive research on its predictors is needed. This study aimed to examine whether and how job satisfaction and work-related burnout affect personal burnout. Methods. A structured questionnaire was used to collect primary data. The sample consists of 218 employees from transfusion medicine units located in five cities in the central part of Serbia. Descriptive statistical analysis, correlation, and hierarchical regression were applied. Results. We found the personal burnout is negatively affected by job satisfaction, predominantly by working conditions (? = -0,141, t = -2,780, p < 0.01), and positively impacted to work-related burnout (? = 0,690, t = 13,409, p < 0.001) indicated that workload has strong impact on personal life quality of healthcare professionals employed in blood banks. Conclusion. This research contributes to more comprehensive understanding of personal burnout factors. The findings of this study can be used to develop strategies to promote employee well-being and prevent burnout in different manifestations.","PeriodicalId":22263,"journal":{"name":"Srpski arhiv za celokupno lekarstvo","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68731752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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