首页 > 最新文献

Taiwanese Journal of Psychiatry最新文献

英文 中文
Mental health legislation in the Philippines: Its beginnings, highlights, and updates 菲律宾的精神卫生立法:它的开端、重点和更新
Pub Date : 2022-04-01 DOI: 10.4103/tpsy.tpsy_13_22
Réné M. Samaniego
Background: The Philippines is an autonomous Southeast Asian country which has long been encumbered with the burden of mental health-related concerns. Aside from the commonly occurring psychiatric illnesses, it also has to contend with the dearth of epidemiological data on such disorders as well as the scarcity of mental health practitioners. On top of these, one enduring challenge is the absence of mental health legislation. Thus, the passage of Republic Act (R.A.) 11036 or the Philippine Mental Health Act has been considered one of the greater achievements in Philippine psychiatry in the recent years. Methods: In this review, the author examines the origins, highlights, and updates on the legislature of R.A. 11036. Results: This legislature (or the Philippine Mental Health Act) elaborates on its highlights which equitably covers the rights of patients and their families as well as that of the mental health professionals; the standards of psychiatric, psychosocial, and neurologic services that need to be upheld in both government and private hospitals; the promotion of mental health in educational institutions and in the workplace; the need for mental health providers to undergo capacity building and proper training in research and development; the duties and responsibilities of the government agencies involved; the creation of a council to serve as a policymaking, planning, coordinating, and advisory body to oversee the implementation of the law; and the penalty clauses involved with violations of the law. It also provides updates on the enactment of the law's implementing rules and regulations, namely, the upgrading of existing mental health facilities, the standardization of a community-based mental health program, the development of a national suicide prevention strategy, the integration of mental health into the educational system and the workplace, the first-ever Philippine national survey on mental health and well-being, as well as the augmentation of the practice of telepsychiatry to extend the reach of services to the geographically isolated Filipinos. Conclusion: The Philippines made a history through the passage of the first-ever Mental Health Act on June 21, 2018, now known as R.A. 11036. The Philippine Psychiatric Association and other related organizations spearheaded a multisectoral lobby in the drafting of the bill. It took 16 years, and 31 drafts before R.A. 11036 became a reality. We still need to monitor the implementation of the law closely. Future revisions are expected to better improve the mental health law for citizens to receive better rights of mental health treatment and human rights protection.
背景:菲律宾是一个东南亚自治国家,长期以来一直受到精神健康问题的困扰。除了常见的精神疾病外,它还必须应对关于这类疾病的流行病学数据的缺乏以及精神卫生从业人员的缺乏。除此之外,一个持久的挑战是缺乏心理健康立法。因此,《共和国法案》(R.A.)第11036号或《菲律宾精神卫生法》的通过被认为是近年来菲律宾精神病学取得的更大成就之一。方法:本文回顾了R.A. 11036立法的起源、重点和更新。结果:该立法机构(或菲律宾精神卫生法)详细阐述了其重点,其中公平地涵盖了患者及其家属以及精神卫生专业人员的权利;政府医院和私立医院都需要坚持的精神病学、社会心理和神经病学服务标准;在教育机构和工作场所促进心理健康;精神保健提供者需要在研究和发展方面进行能力建设和适当培训;有关政府机构的职责;设立一个委员会,作为决策、规划、协调和咨询机构,监督法律的实施;以及涉及违法行为的处罚条款。它还提供了颁布法律实施细则和条例的最新情况,即升级现有的精神卫生设施、使社区精神卫生方案标准化、制定国家预防自杀战略、将精神卫生纳入教育系统和工作场所、菲律宾首次全国精神卫生和福利调查。以及扩大远程精神病学的实践,将服务范围扩大到地理上孤立的菲律宾人。结论:菲律宾于2018年6月21日通过了有史以来第一部《精神卫生法》,现在被称为R.A. 11036,创造了历史。菲律宾精神病学协会和其他有关组织在起草该法案时带头进行了多部门游说。在R.A. 11036成为现实之前,它花了16年时间,起草了31份草案。我们仍需密切监察法例的执行情况。预计今后的修订将更好地完善精神卫生法,使公民获得更好的精神健康治疗和人权保护的权利。
{"title":"Mental health legislation in the Philippines: Its beginnings, highlights, and updates","authors":"Réné M. Samaniego","doi":"10.4103/tpsy.tpsy_13_22","DOIUrl":"https://doi.org/10.4103/tpsy.tpsy_13_22","url":null,"abstract":"Background: The Philippines is an autonomous Southeast Asian country which has long been encumbered with the burden of mental health-related concerns. Aside from the commonly occurring psychiatric illnesses, it also has to contend with the dearth of epidemiological data on such disorders as well as the scarcity of mental health practitioners. On top of these, one enduring challenge is the absence of mental health legislation. Thus, the passage of Republic Act (R.A.) 11036 or the Philippine Mental Health Act has been considered one of the greater achievements in Philippine psychiatry in the recent years. Methods: In this review, the author examines the origins, highlights, and updates on the legislature of R.A. 11036. Results: This legislature (or the Philippine Mental Health Act) elaborates on its highlights which equitably covers the rights of patients and their families as well as that of the mental health professionals; the standards of psychiatric, psychosocial, and neurologic services that need to be upheld in both government and private hospitals; the promotion of mental health in educational institutions and in the workplace; the need for mental health providers to undergo capacity building and proper training in research and development; the duties and responsibilities of the government agencies involved; the creation of a council to serve as a policymaking, planning, coordinating, and advisory body to oversee the implementation of the law; and the penalty clauses involved with violations of the law. It also provides updates on the enactment of the law's implementing rules and regulations, namely, the upgrading of existing mental health facilities, the standardization of a community-based mental health program, the development of a national suicide prevention strategy, the integration of mental health into the educational system and the workplace, the first-ever Philippine national survey on mental health and well-being, as well as the augmentation of the practice of telepsychiatry to extend the reach of services to the geographically isolated Filipinos. Conclusion: The Philippines made a history through the passage of the first-ever Mental Health Act on June 21, 2018, now known as R.A. 11036. The Philippine Psychiatric Association and other related organizations spearheaded a multisectoral lobby in the drafting of the bill. It took 16 years, and 31 drafts before R.A. 11036 became a reality. We still need to monitor the implementation of the law closely. Future revisions are expected to better improve the mental health law for citizens to receive better rights of mental health treatment and human rights protection.","PeriodicalId":22278,"journal":{"name":"Taiwanese Journal of Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74562761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The link between mind-wandering and performance in a sustained attention to response test in adults with attention-deficit/hyperactivity disorder symptoms 在有注意力缺陷/多动障碍症状的成年人的持续注意力反应测试中,走神与表现之间的联系
Pub Date : 2022-04-01 DOI: 10.4103/tpsy.tpsy_16_22
S. Gau, Shoou-Lian Hwang-Gu, Ying Lin, Chia-Fen Hsu, H. Ni
Objectives: The symptoms of attention-deficit/hyperactivity disorder (ADHD) have been positively documented to be correlated with unintentional mind-wandering (MW) in the literature. In this study, we intended to explore the link between the types of MW and the attention laboratory performance in adults with ADHD symptoms. Methods: We recruited 24 adult patients with ADHD and 30 controls: (a) to receive a semi-structured psychiatric interview for ADHD and other diagnoses, (b) to complete questionnaires about adult ADHD symptoms and other psychiatric symptoms, (c) to receive intelligence assessment, (d) to have thought probes during a Sustained Attention to Response Task (SART), and (e) to be assessed with the MW: Spontaneous Scale (WM-S). Results: Adult patients with ADHD symptoms showed a more impulsive SART response style (increased commission errors and fast response speed) and unintentional MW. Increased unintentional MW was associated with reduced task performance. A positive association existed between MW-S scores and unintentional MW during the SART. Conclusion: Spontaneous MW may be significant impairment in adults with ADHD. Different measurements of MW had the associated and consistent findings measured by cognitive laboratory task with thought probe or WM-S measurement.
目的:注意缺陷/多动障碍(ADHD)的症状已被文献证实与无意走神(MW)相关。在本研究中,我们旨在探讨ADHD症状的成人中,MW类型与注意实验室表现之间的联系。方法:我们招募了24名成年ADHD患者和30名对照者:(a)接受针对ADHD和其他诊断的半结构化精神病学访谈,(b)完成关于成人ADHD症状和其他精神症状的问卷调查,(c)接受智力评估,(d)在持续注意反应任务(SART)中进行思维探测,(e)用MW:自发量表(WM-S)进行评估。结果:成年ADHD患者表现出更冲动性的SART反应方式(委托错误增加,反应速度快)和非故意的MW。增加无意的MW与降低任务绩效有关。在SART期间,MW- s评分与非故意MW之间存在正相关。结论:自发性MW可能是成人ADHD患者的显著损害。认知实验室任务与思维探针或WM-S测量测量的不同测量结果具有相关性和一致性。
{"title":"The link between mind-wandering and performance in a sustained attention to response test in adults with attention-deficit/hyperactivity disorder symptoms","authors":"S. Gau, Shoou-Lian Hwang-Gu, Ying Lin, Chia-Fen Hsu, H. Ni","doi":"10.4103/tpsy.tpsy_16_22","DOIUrl":"https://doi.org/10.4103/tpsy.tpsy_16_22","url":null,"abstract":"Objectives: The symptoms of attention-deficit/hyperactivity disorder (ADHD) have been positively documented to be correlated with unintentional mind-wandering (MW) in the literature. In this study, we intended to explore the link between the types of MW and the attention laboratory performance in adults with ADHD symptoms. Methods: We recruited 24 adult patients with ADHD and 30 controls: (a) to receive a semi-structured psychiatric interview for ADHD and other diagnoses, (b) to complete questionnaires about adult ADHD symptoms and other psychiatric symptoms, (c) to receive intelligence assessment, (d) to have thought probes during a Sustained Attention to Response Task (SART), and (e) to be assessed with the MW: Spontaneous Scale (WM-S). Results: Adult patients with ADHD symptoms showed a more impulsive SART response style (increased commission errors and fast response speed) and unintentional MW. Increased unintentional MW was associated with reduced task performance. A positive association existed between MW-S scores and unintentional MW during the SART. Conclusion: Spontaneous MW may be significant impairment in adults with ADHD. Different measurements of MW had the associated and consistent findings measured by cognitive laboratory task with thought probe or WM-S measurement.","PeriodicalId":22278,"journal":{"name":"Taiwanese Journal of Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85945393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Psychological characteristics of sexual preference after incest 乱伦后性偏好的心理特征
Pub Date : 2022-04-01 DOI: 10.4103/tpsy.tpsy_18_22
Hsing-Jung Li, Y. Lin
{"title":"Psychological characteristics of sexual preference after incest","authors":"Hsing-Jung Li, Y. Lin","doi":"10.4103/tpsy.tpsy_18_22","DOIUrl":"https://doi.org/10.4103/tpsy.tpsy_18_22","url":null,"abstract":"","PeriodicalId":22278,"journal":{"name":"Taiwanese Journal of Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79647340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Multidimensional impact of mental illness on tribal families in India 精神疾病对印度部落家庭的多方面影响
Pub Date : 2022-04-01 DOI: 10.4103/tpsy.tpsy_11_22
C. Subudhi, R. Biswal, Abhijit Pathak
Background: Mental illness and burden of care on family is widely discussed in the context of the general population. However, mental health in tribal people also needs the same attention from researchers. In this study, the authors intended to find out the effect of mental illness on tribal families having a person with mental illness. Methods: A descriptive study was done to collect data at the Ispat General Hospital from 50 tribal respondents who were admitted to the Department of Psychiatry. We used open-ended questions to collect the qualitative data. Then, we did content analysis to build themes of the issues of their mental illnesses. Results: We found that the effect of mental illness is on education, marriage, financial crisis, family stress, disruption of family routine activities, physical abuse and violence in the family, social isolation, lack of caregiver's personal care and care for other children in the family, as well as damage to household accessories. Conclusion: In this study, the authors created major themes, to dissect and trisect into adverse events, which were frequent and appear the same in the general and tribal family having a patient with mental illness.
背景:精神疾病和家庭护理负担在普通人群中被广泛讨论。然而,部落居民的心理健康也需要研究人员同样的关注。在这项研究中,作者试图找出精神疾病对有精神疾病患者的部落家庭的影响。方法:在Ispat总医院进行了一项描述性研究,收集了精神病科收治的50名部落受访者的数据。我们使用开放式问题来收集定性数据。然后,我们做了内容分析,以建立他们的精神疾病问题的主题。结果:心理疾病的影响主要表现在教育、婚姻、经济危机、家庭压力、家庭日常活动中断、家庭暴力和身体虐待、社会孤立、缺乏照顾者的个人照顾和对家庭其他孩子的照顾以及家庭用品的损坏等方面。结论:在本研究中,作者创建了主要主题,对一般和部落精神疾病患者家庭中常见且出现相同的不良事件进行了剖析和三分。
{"title":"Multidimensional impact of mental illness on tribal families in India","authors":"C. Subudhi, R. Biswal, Abhijit Pathak","doi":"10.4103/tpsy.tpsy_11_22","DOIUrl":"https://doi.org/10.4103/tpsy.tpsy_11_22","url":null,"abstract":"Background: Mental illness and burden of care on family is widely discussed in the context of the general population. However, mental health in tribal people also needs the same attention from researchers. In this study, the authors intended to find out the effect of mental illness on tribal families having a person with mental illness. Methods: A descriptive study was done to collect data at the Ispat General Hospital from 50 tribal respondents who were admitted to the Department of Psychiatry. We used open-ended questions to collect the qualitative data. Then, we did content analysis to build themes of the issues of their mental illnesses. Results: We found that the effect of mental illness is on education, marriage, financial crisis, family stress, disruption of family routine activities, physical abuse and violence in the family, social isolation, lack of caregiver's personal care and care for other children in the family, as well as damage to household accessories. Conclusion: In this study, the authors created major themes, to dissect and trisect into adverse events, which were frequent and appear the same in the general and tribal family having a patient with mental illness.","PeriodicalId":22278,"journal":{"name":"Taiwanese Journal of Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90310299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Concerns on methods while altering intervals in the questionnaire – Results that are statistically fixed: commenting on perceived stress and its correlates among medical trainees in Oman – A single-institution study 在改变问卷间隔时对方法的关注————统计上固定的结果:评论阿曼医疗培训生的感知压力及其相关性————一项单机构研究
Pub Date : 2022-04-01 DOI: 10.4103/tpsy.tpsy_21_22
H. Ahmed
{"title":"Concerns on methods while altering intervals in the questionnaire – Results that are statistically fixed: commenting on perceived stress and its correlates among medical trainees in Oman – A single-institution study","authors":"H. Ahmed","doi":"10.4103/tpsy.tpsy_21_22","DOIUrl":"https://doi.org/10.4103/tpsy.tpsy_21_22","url":null,"abstract":"","PeriodicalId":22278,"journal":{"name":"Taiwanese Journal of Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89654902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Depression and violent automatism in lissencephaly with epilepsy: A case report 无脑畸形伴癫痫的抑郁和暴力自动性行为1例
Pub Date : 2022-04-01 DOI: 10.4103/tpsy.tpsy_19_22
Y. Lo, Ya-Pin Hsu
{"title":"Depression and violent automatism in lissencephaly with epilepsy: A case report","authors":"Y. Lo, Ya-Pin Hsu","doi":"10.4103/tpsy.tpsy_19_22","DOIUrl":"https://doi.org/10.4103/tpsy.tpsy_19_22","url":null,"abstract":"","PeriodicalId":22278,"journal":{"name":"Taiwanese Journal of Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78392590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Coronavirus phase and major influencing factors in determining anxiety, depression, and posttraumatic stress disorder in patients with COVID-19 COVID-19患者焦虑、抑郁和创伤后应激障碍的冠状病毒期及主要影响因素
Pub Date : 2022-04-01 DOI: 10.4103/tpsy.tpsy_14_22
S. Satapathy, L. Wundavalli, R. Chadda, S. Satpathy, Shraddhesh Kumar Tiwari, Sheetal Singh, A. Singh, Y. Kumar, V. Barre
Objectives: We investigated the prevalence and risk factors of psychological distress, depression, anxiety, and posttraumatic stress disorder (PTSD) among COVID-19 inpatients during the initial and peak coronavirus phase in the largest public sector hospital in India. Methods: With a prospective observational design, we included 761 male and female COVID-19-hospitalized patients. The Self-Reporting Questionnaire, Primary Care PTSD Screen for DSM-5 (PC-PTSD-5), and Hospital Anxiety and Depression Scale were used. Results: Totally, 612 males and 149 females had a mean age of 36.68 ± 11.72 (mean ± standard deviation) years. The prevalences of psychological distress, anxiety, depression, and PTSD symptoms for the total sample were 12.6%, 19.2%, 19.2%, and 8.4%, respectively. Significant differences existed in the prevalence of psychological distress, anxiety, and depression between the initial coronavirus and peak coronavirus phase (13.7% vs. 11%, χ2 = 9.37 p < 0.01), 22.1% vs. 14.7%, χ2 = 23.04, p < 0.01), 21.04% vs. 16.3%, χ2 = 15.78, p < 0.01) but not in that of PTSD. Except for psychological distress, there was no gender difference. Coronavirus phase and employment status had significant interaction effects (p < 0.01) on anxiety and depression. Conclusion: Younger age, males in full-time jobs, in marital relationship, poor socioeconomic status were the risk factors, and comorbidity was the important risk factor. The result of this study could highlight the need for compulsory mental health screening and necessary medical/non-medical mental health support to all admitted patients.
目的:我们调查了印度最大的公立医院COVID-19住院患者在冠状病毒初期和高峰阶段的心理困扰、抑郁、焦虑和创伤后应激障碍(PTSD)的患病率和危险因素。方法:采用前瞻性观察设计,纳入761例新冠肺炎住院患者。采用自我报告问卷、DSM-5初级保健PTSD筛查(PC-PTSD-5)和医院焦虑抑郁量表。结果:男性612人,女性149人,平均年龄36.68±11.72岁(平均±标准差)。总样本中心理困扰、焦虑、抑郁和PTSD症状的患病率分别为12.6%、19.2%、19.2%和8.4%。冠状病毒初始期与冠状病毒高峰期患者的心理困扰、焦虑、抑郁患病率差异有统计学意义(13.7% vs. 11%, χ2 = 9.37 p < 0.01), 22.1% vs. 14.7%, χ2 = 23.04, p < 0.01), 21.04% vs. 16.3%, χ2 = 15.78, p < 0.01), PTSD无统计学意义(p < 0.01)。除心理困扰外,无性别差异。冠状病毒阶段与就业状态对焦虑和抑郁有显著交互作用(p < 0.01)。结论:年龄偏小、男性全职工作、婚姻关系不稳定、社会经济状况不佳是该病的危险因素,其中合并症是重要的危险因素。本研究的结果可以强调对所有住院患者进行强制性心理健康筛查和必要的医疗/非医疗心理健康支持的必要性。
{"title":"Coronavirus phase and major influencing factors in determining anxiety, depression, and posttraumatic stress disorder in patients with COVID-19","authors":"S. Satapathy, L. Wundavalli, R. Chadda, S. Satpathy, Shraddhesh Kumar Tiwari, Sheetal Singh, A. Singh, Y. Kumar, V. Barre","doi":"10.4103/tpsy.tpsy_14_22","DOIUrl":"https://doi.org/10.4103/tpsy.tpsy_14_22","url":null,"abstract":"Objectives: We investigated the prevalence and risk factors of psychological distress, depression, anxiety, and posttraumatic stress disorder (PTSD) among COVID-19 inpatients during the initial and peak coronavirus phase in the largest public sector hospital in India. Methods: With a prospective observational design, we included 761 male and female COVID-19-hospitalized patients. The Self-Reporting Questionnaire, Primary Care PTSD Screen for DSM-5 (PC-PTSD-5), and Hospital Anxiety and Depression Scale were used. Results: Totally, 612 males and 149 females had a mean age of 36.68 ± 11.72 (mean ± standard deviation) years. The prevalences of psychological distress, anxiety, depression, and PTSD symptoms for the total sample were 12.6%, 19.2%, 19.2%, and 8.4%, respectively. Significant differences existed in the prevalence of psychological distress, anxiety, and depression between the initial coronavirus and peak coronavirus phase (13.7% vs. 11%, χ2 = 9.37 p < 0.01), 22.1% vs. 14.7%, χ2 = 23.04, p < 0.01), 21.04% vs. 16.3%, χ2 = 15.78, p < 0.01) but not in that of PTSD. Except for psychological distress, there was no gender difference. Coronavirus phase and employment status had significant interaction effects (p < 0.01) on anxiety and depression. Conclusion: Younger age, males in full-time jobs, in marital relationship, poor socioeconomic status were the risk factors, and comorbidity was the important risk factor. The result of this study could highlight the need for compulsory mental health screening and necessary medical/non-medical mental health support to all admitted patients.","PeriodicalId":22278,"journal":{"name":"Taiwanese Journal of Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88682953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations between brain-derived neurotrophic factor val66met polymorphism, melancholic feature, and treatment refractoriness in patients with treatment-resistant depression 难治性抑郁症患者脑源性神经营养因子val66met多态性、抑郁特征和治疗难治性的关系
Pub Date : 2022-04-01 DOI: 10.4103/tpsy.tpsy_15_22
Yu- Lin, S. Tsai, Mu-Hong Chen
Background: Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism is related to the pathophysiology of treatment-resistant depression (TRD). But whether the Val66Met polymorphism is associated with the clinical manifestations of TRD (such as treatment refractoriness and melancholic and anxious distress features) remains unclear. Methods: Totally, 106 patients with TRD were genotyped for the BDNF Val66Met polymorphism. We used the 17-item Hamilton Depression Rating Scale evaluate depressive symptoms (melancholic and anxious distress features) and Maudsley Staging Method to measure treatment refractoriness. Logistic regression models were constructed to study the relationships among the Val66Met polymorphism, melancholic or anxious distress features, and treatment refractoriness. Results: The risk of Val/Met heterozygosity was associated with significantly greater melancholic features than that of Val/Val homozygosity (odds ratio [95% confidence interval (CI)] = (4.67 [1.16–14.24], p < 0.05). The melancholic feature in Val/Met heterozygosity was significantly higher to have the risk in treatment refractoriness than that of Val/Val homozygosity odd ratio (95% CI) = (6.42 [1.70–24.25], p < 0.05). Conclusion: Patients with TRD carrying the BDNF Val/Met genotype are more likely to present with melancholic feature, which is in turn related to high treatment refractoriness.
背景:脑源性神经营养因子(BDNF) Val66Met多态性与难治性抑郁症(TRD)的病理生理有关。但Val66Met多态性是否与TRD的临床表现(如治疗难治性、忧郁焦虑苦恼特征)相关尚不清楚。方法:对106例TRD患者进行BDNF Val66Met多态性基因分型。我们采用17项汉密尔顿抑郁评定量表评估抑郁症状(忧郁和焦虑困扰特征),并采用莫兹利分期法测量治疗难治性。构建Logistic回归模型,研究Val66Met多态性、忧郁或焦虑困扰特征与治疗难治性的关系。结果:Val/Met杂合性与忧郁特征的相关风险显著高于Val/Val纯合性(优势比[95%置信区间(CI)] = (4.67 [1.16-14.24], p < 0.05)。Val/Met杂合度的忧郁特征明显高于Val/Val纯合度奇比(95% CI) = (6.42 [1.70-24.25], p < 0.05)。结论:携带BDNF Val/Met基因型的TRD患者更容易出现抑郁特征,这与治疗难治性高有关。
{"title":"Associations between brain-derived neurotrophic factor val66met polymorphism, melancholic feature, and treatment refractoriness in patients with treatment-resistant depression","authors":"Yu- Lin, S. Tsai, Mu-Hong Chen","doi":"10.4103/tpsy.tpsy_15_22","DOIUrl":"https://doi.org/10.4103/tpsy.tpsy_15_22","url":null,"abstract":"Background: Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism is related to the pathophysiology of treatment-resistant depression (TRD). But whether the Val66Met polymorphism is associated with the clinical manifestations of TRD (such as treatment refractoriness and melancholic and anxious distress features) remains unclear. Methods: Totally, 106 patients with TRD were genotyped for the BDNF Val66Met polymorphism. We used the 17-item Hamilton Depression Rating Scale evaluate depressive symptoms (melancholic and anxious distress features) and Maudsley Staging Method to measure treatment refractoriness. Logistic regression models were constructed to study the relationships among the Val66Met polymorphism, melancholic or anxious distress features, and treatment refractoriness. Results: The risk of Val/Met heterozygosity was associated with significantly greater melancholic features than that of Val/Val homozygosity (odds ratio [95% confidence interval (CI)] = (4.67 [1.16–14.24], p < 0.05). The melancholic feature in Val/Met heterozygosity was significantly higher to have the risk in treatment refractoriness than that of Val/Val homozygosity odd ratio (95% CI) = (6.42 [1.70–24.25], p < 0.05). Conclusion: Patients with TRD carrying the BDNF Val/Met genotype are more likely to present with melancholic feature, which is in turn related to high treatment refractoriness.","PeriodicalId":22278,"journal":{"name":"Taiwanese Journal of Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79850955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Community mental health care in the era of COVID-19 pandemic COVID-19大流行时代的社区精神卫生服务
Pub Date : 2022-01-01 DOI: 10.4103/tpsy.tpsy_12_22
Chang-Jer Tsai
{"title":"Community mental health care in the era of COVID-19 pandemic","authors":"Chang-Jer Tsai","doi":"10.4103/tpsy.tpsy_12_22","DOIUrl":"https://doi.org/10.4103/tpsy.tpsy_12_22","url":null,"abstract":"","PeriodicalId":22278,"journal":{"name":"Taiwanese Journal of Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75728849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Target stigma in schools: Teach them young 针对学校的污名:从小教育他们
Pub Date : 2022-01-01 DOI: 10.4103/tpsy.tpsy_8_22
Arghya Pal
{"title":"Target stigma in schools: Teach them young","authors":"Arghya Pal","doi":"10.4103/tpsy.tpsy_8_22","DOIUrl":"https://doi.org/10.4103/tpsy.tpsy_8_22","url":null,"abstract":"","PeriodicalId":22278,"journal":{"name":"Taiwanese Journal of Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73372779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Taiwanese Journal of Psychiatry
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1