Objectives The aim of this study was to evaluate clinically and radiographically, the effectiveness of autologous demineralized dentin graft with or without concentrated growth factor (CGF) around immediate-delayed implant in type II sockets in patients with advanced chronic periodontitis. Materials and methods In the present study, 16 sites with periodontally hopeless single rooted teeth in nine patients. Sites were divided randomly into: group I, which was treated with autologous demineralized dentin graft, and group II was treated with autologous demineralized dentin graft with CGF. At time of crown placement after 6, 9- and 12-months probing pocket depth and bleeding on probing around implant were assessed. Radiographically, facial bone thickness (FBT) and bone density were estimated by using standardized cone beam computed tomography after tooth extraction, immediately after surgery, nine and twelve months later. Results Regarding clinical parameters, both groups showed nonsignificant differences after 6, 9, and 12 months as compared to baseline measures. Upon comparing the groups in terms of pocket depth and bleeding on probing, also showed nonsignificant difference at all study evaluation periods. Radiographic analysis by cone beam computed tomography showed a significant reduction in FBT in two groups at 9 and 12 months as compared to thickness immediately after implant placement. On the other hand, there was a nonstatistically significant difference in FBT between both groups. Regarding bone density, the results showed significant increase in bone density in two groups without significant difference between both groups however, more density was observed in group II. Conclusion The combined treatment of CGF with autologous demineralized dentin graft showed better results, however nonsignificant difference was noted radiographically when compared with autologous demineralized dentin graft alone, it was therefore postulated that, the addition of CGF to autologous demineralized dentin graft may have been a promising outcomed in the field of periodontal regeneration.
{"title":"Evaluation of fresh demineralized dentin graft with or without concentrated growth factor in guided bone regeneration around dental implant","authors":"A. El-Ghaysh, Amal Al-Hessy, M. El-Razzak","doi":"10.4103/tdj.tdj_36_22","DOIUrl":"https://doi.org/10.4103/tdj.tdj_36_22","url":null,"abstract":"Objectives The aim of this study was to evaluate clinically and radiographically, the effectiveness of autologous demineralized dentin graft with or without concentrated growth factor (CGF) around immediate-delayed implant in type II sockets in patients with advanced chronic periodontitis. Materials and methods In the present study, 16 sites with periodontally hopeless single rooted teeth in nine patients. Sites were divided randomly into: group I, which was treated with autologous demineralized dentin graft, and group II was treated with autologous demineralized dentin graft with CGF. At time of crown placement after 6, 9- and 12-months probing pocket depth and bleeding on probing around implant were assessed. Radiographically, facial bone thickness (FBT) and bone density were estimated by using standardized cone beam computed tomography after tooth extraction, immediately after surgery, nine and twelve months later. Results Regarding clinical parameters, both groups showed nonsignificant differences after 6, 9, and 12 months as compared to baseline measures. Upon comparing the groups in terms of pocket depth and bleeding on probing, also showed nonsignificant difference at all study evaluation periods. Radiographic analysis by cone beam computed tomography showed a significant reduction in FBT in two groups at 9 and 12 months as compared to thickness immediately after implant placement. On the other hand, there was a nonstatistically significant difference in FBT between both groups. Regarding bone density, the results showed significant increase in bone density in two groups without significant difference between both groups however, more density was observed in group II. Conclusion The combined treatment of CGF with autologous demineralized dentin graft showed better results, however nonsignificant difference was noted radiographically when compared with autologous demineralized dentin graft alone, it was therefore postulated that, the addition of CGF to autologous demineralized dentin graft may have been a promising outcomed in the field of periodontal regeneration.","PeriodicalId":22324,"journal":{"name":"Tanta Dental Journal","volume":"157 1","pages":"254 - 263"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86340623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim To evaluate the effect of aloe vera versus nanosilver (NS) mouthwashes in comparison with chlorhexidine on plaque-induced gingivitis. Patients and methods Sixty patients with plaque-induced gingivitis were assigned to three groups and asked to rinse with 10 ml of aloe vera, NS or chlorhexidine, immediately after brushing for 1 min. The plaque, gingival, and papilla bleeding indices were taken at baseline, 2 weeks, and after 4 weeks. Results There were statistically significant differences in all investigated parameters after 2 and 4 weeks as compared to the baseline in all groups. While there were no significant differences between the groups during any evaluation period. Aloe vera and NS mouthwashes showed no side effects. Conclusion The results indicated that aloe vera and NS mouthwashes can be used as effective mouthwashes without any side effects.
{"title":"Clinical efficacy of aloe vera, nanosilver, and chlorhexidine in the treatment of plaque-induced gingivitis","authors":"Sherouk El Din, M. Sabry, Ahmed Elgendy","doi":"10.4103/tdj.tdj_45_22","DOIUrl":"https://doi.org/10.4103/tdj.tdj_45_22","url":null,"abstract":"Aim To evaluate the effect of aloe vera versus nanosilver (NS) mouthwashes in comparison with chlorhexidine on plaque-induced gingivitis. Patients and methods Sixty patients with plaque-induced gingivitis were assigned to three groups and asked to rinse with 10 ml of aloe vera, NS or chlorhexidine, immediately after brushing for 1 min. The plaque, gingival, and papilla bleeding indices were taken at baseline, 2 weeks, and after 4 weeks. Results There were statistically significant differences in all investigated parameters after 2 and 4 weeks as compared to the baseline in all groups. While there were no significant differences between the groups during any evaluation period. Aloe vera and NS mouthwashes showed no side effects. Conclusion The results indicated that aloe vera and NS mouthwashes can be used as effective mouthwashes without any side effects.","PeriodicalId":22324,"journal":{"name":"Tanta Dental Journal","volume":"29 1","pages":"269 - 272"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79462478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction Despite being a rare daily histopathologic diagnosis, malignant salivary gland (SG) tumors show significant morphologic diversity that could obscure their diagnosis. Recognizing specific microscopic patterns together with the aid of ancillary techniques, such as immunohistochemistry, represent the clues to precise diagnosis. Mammaglobin (MMg) is a member of secretoglobin protein family that is widely associated with breast cancer and strongly expressed by secretory carcinoma of SGs. Its expression in other malignant SG neoplasms should be investigated. Objectives Investigating the immunohistochemical expression of MMg in some malignant SG tumors to detect its potential diagnostic value. Material and Methods Nineteen paraffin-embedded, archival specimens of malignant SG tumors were divided into two groups according to presence or absence of ductal differentiation. Specimens were immunohistochemically stained using anti-MMg protein. Results MMg expression was more upregulated in the ductal differentiation group as compared to the other group of neoplasms. Conclusion MMg would represent a promising diagnostic tool in discriminating SG tumors with ductal and/or secretory activity.
{"title":"Mammaglobin immunoexpression in some malignant salivary gland neoplasms as a potential diagnostic tool for tumor ductal differentiation","authors":"Basant Zaid, O. Wahba, H. Youssef","doi":"10.4103/tdj.tdj_26_22","DOIUrl":"https://doi.org/10.4103/tdj.tdj_26_22","url":null,"abstract":"Introduction Despite being a rare daily histopathologic diagnosis, malignant salivary gland (SG) tumors show significant morphologic diversity that could obscure their diagnosis. Recognizing specific microscopic patterns together with the aid of ancillary techniques, such as immunohistochemistry, represent the clues to precise diagnosis. Mammaglobin (MMg) is a member of secretoglobin protein family that is widely associated with breast cancer and strongly expressed by secretory carcinoma of SGs. Its expression in other malignant SG neoplasms should be investigated. Objectives Investigating the immunohistochemical expression of MMg in some malignant SG tumors to detect its potential diagnostic value. Material and Methods Nineteen paraffin-embedded, archival specimens of malignant SG tumors were divided into two groups according to presence or absence of ductal differentiation. Specimens were immunohistochemically stained using anti-MMg protein. Results MMg expression was more upregulated in the ductal differentiation group as compared to the other group of neoplasms. Conclusion MMg would represent a promising diagnostic tool in discriminating SG tumors with ductal and/or secretory activity.","PeriodicalId":22324,"journal":{"name":"Tanta Dental Journal","volume":"25 1","pages":"235 - 240"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86092123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
NohaM. H ELkafoury, S. Asal, Ahmed Mohamed Alam-Eldein
Introduction In-vitro studies are required to predict the outcomes of in-vivo studies. Reliability of simulation protocols used in in-vitro test is an indication for its creditability. Up to our knowledge, no in-vitro method is yet available based on which resin material discoloration can be assessed with a high degree of sensitivity and specificity. Likely, there will never be a single laboratory test or a collection of tests that will accurately predict the clinical performance on specific materials. This, however, should not be an excuse for not improving and validating the laboratory test methods. Purpose To evaluate the effect of two different simulation protocol using the same discoloring agents and effect of brushing on color stability of heat cure acrylic resin denture base. Materials and Methods One hundred twenty heat cure acrylic resin disk samples, all were exposed to coffee, roselle, and cigarette smoke for a simulation period representing three months: half of samples were immersed in simulation mediums continuously without artificial saliva. Group A, the other half was exposed to simulation mediums and artificial saliva in a term of cycle repeated daily. Group B, each half was subdivided into two subgroups, one subgroup was brushed with soft toothbrush under water (A2, B2) while the other subgroup was rinsed with water (A1, B1). Color measurement was conducted by portable spectrophotometer. Results Statistically significant difference between the four subgroups, the highest color change was reported for subgroup (A1) followed by subgroups (A2, B1, B2) in order. Conclusion Simulation protocol in term of a cycle repeated daily is more representative to the oral cavity than continuous protocol, patients must be instructed to perform hygienic procedures daily to maintain the denture esthetics.
{"title":"Two different in-vitro simulation protocols to evaluate the color stability of heat cure acrylic resin denture base","authors":"NohaM. H ELkafoury, S. Asal, Ahmed Mohamed Alam-Eldein","doi":"10.4103/tdj.tdj_24_22","DOIUrl":"https://doi.org/10.4103/tdj.tdj_24_22","url":null,"abstract":"Introduction In-vitro studies are required to predict the outcomes of in-vivo studies. Reliability of simulation protocols used in in-vitro test is an indication for its creditability. Up to our knowledge, no in-vitro method is yet available based on which resin material discoloration can be assessed with a high degree of sensitivity and specificity. Likely, there will never be a single laboratory test or a collection of tests that will accurately predict the clinical performance on specific materials. This, however, should not be an excuse for not improving and validating the laboratory test methods. Purpose To evaluate the effect of two different simulation protocol using the same discoloring agents and effect of brushing on color stability of heat cure acrylic resin denture base. Materials and Methods One hundred twenty heat cure acrylic resin disk samples, all were exposed to coffee, roselle, and cigarette smoke for a simulation period representing three months: half of samples were immersed in simulation mediums continuously without artificial saliva. Group A, the other half was exposed to simulation mediums and artificial saliva in a term of cycle repeated daily. Group B, each half was subdivided into two subgroups, one subgroup was brushed with soft toothbrush under water (A2, B2) while the other subgroup was rinsed with water (A1, B1). Color measurement was conducted by portable spectrophotometer. Results Statistically significant difference between the four subgroups, the highest color change was reported for subgroup (A1) followed by subgroups (A2, B1, B2) in order. Conclusion Simulation protocol in term of a cycle repeated daily is more representative to the oral cavity than continuous protocol, patients must be instructed to perform hygienic procedures daily to maintain the denture esthetics.","PeriodicalId":22324,"journal":{"name":"Tanta Dental Journal","volume":"51 1","pages":"181 - 186"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86754214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mona EL-Meligy, M. El-Razzak, Amal Al-Hessy, Sara Abo-Ali
Objectives The experimental study was designed to evaluate the efficacy of gelatin sponge loaded with β tricalcium phosphate (β-TCP) with or without ReGeneraTing agent (RGTA) in the treatment of mandibular class II furcation defects in advanced periodontitis in vitro. Materials and methods Three Egyptian Baladi dogs were included with average age 13–16 months and average body weight of 9–10 kg. Six critical size defects class II furcation defects were created in the mandible of each dog, three in the right and three in the left mandibular second, third, and fourth premolars. All defects were made in the same way by the same operator. The defects were treated either with RGTA loaded on gelatin/β-TCP sponge or placebo loaded on gelatin sponge/β-TCP in two groups (group I and group II) that blindly received one of the treatment modalities. Samples were collected from the surgical sites of the experimental defects after 12 weeks. Results Histologically and histomorphometrically: there was a statistically significant difference when group I was compared with group II regarding surface area of new bone formation. Conclusion RGTA loaded on gelatin/β-TCP sponge could be considered as a potentiating material for periodontal regeneration.
{"title":"ReGeneraTing agents as matrix-based therapy loaded on gelatin/beta tricalcium phosphate sponge for the treatment of class II furcation defects in vitro","authors":"Mona EL-Meligy, M. El-Razzak, Amal Al-Hessy, Sara Abo-Ali","doi":"10.4103/tdj.tdj_35_22","DOIUrl":"https://doi.org/10.4103/tdj.tdj_35_22","url":null,"abstract":"Objectives The experimental study was designed to evaluate the efficacy of gelatin sponge loaded with β tricalcium phosphate (β-TCP) with or without ReGeneraTing agent (RGTA) in the treatment of mandibular class II furcation defects in advanced periodontitis in vitro. Materials and methods Three Egyptian Baladi dogs were included with average age 13–16 months and average body weight of 9–10 kg. Six critical size defects class II furcation defects were created in the mandible of each dog, three in the right and three in the left mandibular second, third, and fourth premolars. All defects were made in the same way by the same operator. The defects were treated either with RGTA loaded on gelatin/β-TCP sponge or placebo loaded on gelatin sponge/β-TCP in two groups (group I and group II) that blindly received one of the treatment modalities. Samples were collected from the surgical sites of the experimental defects after 12 weeks. Results Histologically and histomorphometrically: there was a statistically significant difference when group I was compared with group II regarding surface area of new bone formation. Conclusion RGTA loaded on gelatin/β-TCP sponge could be considered as a potentiating material for periodontal regeneration.","PeriodicalId":22324,"journal":{"name":"Tanta Dental Journal","volume":"29 1","pages":"247 - 253"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74067399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective The Purpose of the present study was to evaluate the effects of nanosilver fluoride (NSF) on shear bond strength (SBS) of orthodontic brackets and prevention of enamel demineralization. Materials and methods Seventy-five human premolars divided into three group. Brackets were bonded directly to buccal surface using grengloo (Ormco) light cured orthodontic adhesive following manufacturer's instructions. In group I, no intervention was carried out. In group II, NSF was applied for 2 min before acid etching while in group III, NSF was applied for 2 min after acid etching. All samples were then subjected to pH cycle to simulate cariogenic challenge. SBS and adhesive remnant index score were evaluated for all samples then five teeth from each group were prepared for scanning electron microscopic evaluation. Results The mean SBS values were 9.74 ± 3.03, 10.39 ± 2.77, and 10.71 ± 3.34 for group I, II, and III, respectively. The one-way analysis of variance revealed nonsignificant difference among groups. For adhesive remnant index scores, statistically significant difference was found between groups I and II and groups I and III while there was no statistically significant difference between groups II and III. Scanning electron microscopic observations showed deposition of new fluoroapatite crystals with less enamel demineralization in groups II and III. Conclusion NSF could be effectively used for preventing enamel demineralization around orthodontic brackets without negatively affecting the bond strength. The site of bond failure was changed by NSF application with increased adhesive remaining on tooth surface after debonding.
{"title":"In vitro study of the effect of nanosilver fluoride on shear bond strength of orthodontic brackets and demineralization of enamel","authors":"Mariam El-Toukhy, E. El-Shourbagy, N. Fakhry","doi":"10.4103/tdj.tdj_32_22","DOIUrl":"https://doi.org/10.4103/tdj.tdj_32_22","url":null,"abstract":"Objective The Purpose of the present study was to evaluate the effects of nanosilver fluoride (NSF) on shear bond strength (SBS) of orthodontic brackets and prevention of enamel demineralization. Materials and methods Seventy-five human premolars divided into three group. Brackets were bonded directly to buccal surface using grengloo (Ormco) light cured orthodontic adhesive following manufacturer's instructions. In group I, no intervention was carried out. In group II, NSF was applied for 2 min before acid etching while in group III, NSF was applied for 2 min after acid etching. All samples were then subjected to pH cycle to simulate cariogenic challenge. SBS and adhesive remnant index score were evaluated for all samples then five teeth from each group were prepared for scanning electron microscopic evaluation. Results The mean SBS values were 9.74 ± 3.03, 10.39 ± 2.77, and 10.71 ± 3.34 for group I, II, and III, respectively. The one-way analysis of variance revealed nonsignificant difference among groups. For adhesive remnant index scores, statistically significant difference was found between groups I and II and groups I and III while there was no statistically significant difference between groups II and III. Scanning electron microscopic observations showed deposition of new fluoroapatite crystals with less enamel demineralization in groups II and III. Conclusion NSF could be effectively used for preventing enamel demineralization around orthodontic brackets without negatively affecting the bond strength. The site of bond failure was changed by NSF application with increased adhesive remaining on tooth surface after debonding.","PeriodicalId":22324,"journal":{"name":"Tanta Dental Journal","volume":"16 1","pages":"281 - 286"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88648160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background Treatment of ameloblastoma in young patients should be conservative to avoid serious complications resulting from radical surgery. The aim of this study was to evaluate the prognosis of surgical excision with thorough curettage (peripheral ostectomy) in treatment of ameloblastoma in adolescent. Patients and methods This study included eight patients with mandibular ameloblastoma, which was confirmed by preoperative computed tomography and histopathological examination of incisional biopsy specimen and all patients were treated by surgical excision with thorough curettage. Results This study involved six males and two females, with an age ranged from 12 to 16 years with a mean of age 13.75 years. All lesions occurred in the mandible. Recurrence was not observed in seven cases of eight cases after 36 months follow up and occurred only in case no 7. Conclusion Ameloblastoma in adolescents can be successfully treated conservatively by surgical excision with thorough curettage (peripheral ostectomy).
{"title":"Minimally invasive approach in treatment of ameloblastoma in adolescent: 3-years follow-up","authors":"Rafic Beder, Marwa Ibrahim","doi":"10.4103/tdj.tdj_44_22","DOIUrl":"https://doi.org/10.4103/tdj.tdj_44_22","url":null,"abstract":"Background Treatment of ameloblastoma in young patients should be conservative to avoid serious complications resulting from radical surgery. The aim of this study was to evaluate the prognosis of surgical excision with thorough curettage (peripheral ostectomy) in treatment of ameloblastoma in adolescent. Patients and methods This study included eight patients with mandibular ameloblastoma, which was confirmed by preoperative computed tomography and histopathological examination of incisional biopsy specimen and all patients were treated by surgical excision with thorough curettage. Results This study involved six males and two females, with an age ranged from 12 to 16 years with a mean of age 13.75 years. All lesions occurred in the mandible. Recurrence was not observed in seven cases of eight cases after 36 months follow up and occurred only in case no 7. Conclusion Ameloblastoma in adolescents can be successfully treated conservatively by surgical excision with thorough curettage (peripheral ostectomy).","PeriodicalId":22324,"journal":{"name":"Tanta Dental Journal","volume":"1 1","pages":"264 - 268"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83828525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives The aim of this study is evaluating the effect of using various prepartion of dentin matrices on bone regeneration in New Zeland white rabbit model. Design The study was conducted on fifty adult New Zealand rabbits, 20 for preparation of experimental materials and 30 for surgical procedures. They were randomly assigned into three equal groups as follow one control group: no treatment and two experimental groups including demineralized group: treated with demineralized dentin matrix (DDM) only; and mixed group: treated with a hybrid of (50% DDM + 50% undemineralized dentin matrix). A rounded critical size defect (10 mm in diameter, 5 mm in depth) was created in the body of mandible. After 3- and 6-weeks postsurgery, the bone regeneration was evaluated by light microscope and computed tomography analysis. Results Histological and computed tomography analysis revealed that both dentin matrices had largely resorbed and induced new bone formation at both experimental groups compared to the control group, with statistically higher percentage of new bone formation and bone mineral density in the mixed group. Conclusion We concluded that although both dentin matrices improve bone regeneration but, hybrid dentin matrix yielded better results compared to DDM group.
{"title":"The effect of using various dentin matrices on bone regeneration in New Zeland white rabbits: histological and radiografic experimental study","authors":"E. Elkady, Ragia El-den, A. Atiba, S. Yasser","doi":"10.4103/tdj.tdj_34_22","DOIUrl":"https://doi.org/10.4103/tdj.tdj_34_22","url":null,"abstract":"Objectives The aim of this study is evaluating the effect of using various prepartion of dentin matrices on bone regeneration in New Zeland white rabbit model. Design The study was conducted on fifty adult New Zealand rabbits, 20 for preparation of experimental materials and 30 for surgical procedures. They were randomly assigned into three equal groups as follow one control group: no treatment and two experimental groups including demineralized group: treated with demineralized dentin matrix (DDM) only; and mixed group: treated with a hybrid of (50% DDM + 50% undemineralized dentin matrix). A rounded critical size defect (10 mm in diameter, 5 mm in depth) was created in the body of mandible. After 3- and 6-weeks postsurgery, the bone regeneration was evaluated by light microscope and computed tomography analysis. Results Histological and computed tomography analysis revealed that both dentin matrices had largely resorbed and induced new bone formation at both experimental groups compared to the control group, with statistically higher percentage of new bone formation and bone mineral density in the mixed group. Conclusion We concluded that although both dentin matrices improve bone regeneration but, hybrid dentin matrix yielded better results compared to DDM group.","PeriodicalId":22324,"journal":{"name":"Tanta Dental Journal","volume":"16 1","pages":"241 - 246"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85993476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background/aim Rehabilitation of the reconstructed mandibular defect is a challenge. Computer-aided design and computer-aided manufacturing have opened a new successful approach to the fabrication of maxillofacial prostheses. This study aimed to evaluate marginal bone changes of abutments, implant, and bone graft height changes for patients treated with polyetheretherketone removable partial implant-assisted overdenture (RPIAO) in mandibular defect rehabilitation. Patients and methods Ten patients of both sexes (ages ranging from 55 to 65 years with mean age 60 years) having reconstructed mandibular defects and unsatisfied with their conventional partial dentures participated in the study. Each patient was rehabilitated using telescopic RPIAO. The telescopic RPIAO was fabricated digitally from milled polyetheretherketone, and the implant was inserted using a fully guided surgical guide. Marginal bone changes of abutments, implant and bone graft height changes measurements were performed using cone-beam computed tomography during the 9-month follow-up period. Results Range repeated measure analysis of variance was used to comparing bone parameters throwing the durations. After the 9-month follow-up period, the mean and SD of marginal bone level of implants were 7.53 ± 1.25 mm. There was a statistically significant difference between the durations where P value of 0.029. The higher bone loss around the implants occurred in the first 6 months from loading. At the end of the 9-month follow-up period, the mean and SD of marginal bone level of abutments were 10.69 ± 1.53 mm. Between the durations where P value of 0.053, there was no statistically significant difference. At the end of the 9-month follow-up period, the mean and SD of graft height was 16.43 ± 3.04. Between the durations where (P = 0.064), there was no statistically significant difference. Conclusion Within the limitations of this study, regarding marginal bone height around implants, there was a significant decrease in height during 6 months and decreased amount of marginal bone resorption from 6 to 9 months. While for marginal bone height around abutments and bone graft height, there was an insignificant decrease in height during the overall 9 months.
{"title":"Bone changes associated with rehabilitation of mandibular defects with polyetheretherketone removable partial implant-assisted overdentures","authors":"Randa Qaid, Hoda Rashad, F. Abutaleb, A. Sadakah","doi":"10.4103/tdj.tdj_40_22","DOIUrl":"https://doi.org/10.4103/tdj.tdj_40_22","url":null,"abstract":"Background/aim Rehabilitation of the reconstructed mandibular defect is a challenge. Computer-aided design and computer-aided manufacturing have opened a new successful approach to the fabrication of maxillofacial prostheses. This study aimed to evaluate marginal bone changes of abutments, implant, and bone graft height changes for patients treated with polyetheretherketone removable partial implant-assisted overdenture (RPIAO) in mandibular defect rehabilitation. Patients and methods Ten patients of both sexes (ages ranging from 55 to 65 years with mean age 60 years) having reconstructed mandibular defects and unsatisfied with their conventional partial dentures participated in the study. Each patient was rehabilitated using telescopic RPIAO. The telescopic RPIAO was fabricated digitally from milled polyetheretherketone, and the implant was inserted using a fully guided surgical guide. Marginal bone changes of abutments, implant and bone graft height changes measurements were performed using cone-beam computed tomography during the 9-month follow-up period. Results Range repeated measure analysis of variance was used to comparing bone parameters throwing the durations. After the 9-month follow-up period, the mean and SD of marginal bone level of implants were 7.53 ± 1.25 mm. There was a statistically significant difference between the durations where P value of 0.029. The higher bone loss around the implants occurred in the first 6 months from loading. At the end of the 9-month follow-up period, the mean and SD of marginal bone level of abutments were 10.69 ± 1.53 mm. Between the durations where P value of 0.053, there was no statistically significant difference. At the end of the 9-month follow-up period, the mean and SD of graft height was 16.43 ± 3.04. Between the durations where (P = 0.064), there was no statistically significant difference. Conclusion Within the limitations of this study, regarding marginal bone height around implants, there was a significant decrease in height during 6 months and decreased amount of marginal bone resorption from 6 to 9 months. While for marginal bone height around abutments and bone graft height, there was an insignificant decrease in height during the overall 9 months.","PeriodicalId":22324,"journal":{"name":"Tanta Dental Journal","volume":"40 24","pages":"212 - 220"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91402257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nancy Metwally, A. El Hosary, G. E. El Maghraby, M. E. El demellawy, Mohamed Nabil, E. Deraz
Introduction Pulpotomy is a therapeutic procedure comprising surgical amputation of coronally inflamed pulp. Formocresol (FC) continues to be the most widely used pulpotomy medicament for primary teeth. Unfortunately, the cytotoxic and mutagenic effects of FC draw the attention for the need of an effective safer alternative. The use of natural products as capping material provides a promising substitute. Omega 3 (w3) is one of the most widely used natural material to impart therapeutic function. Oral administration of w3 showed promising anti-inflammatory effect in periodontal diseases but no investigation was conducted to monitor its effect locally in the teeth. Objective The aim of this work was to evaluate w3 as pulpotomy agent with reference to FC. The study was extended to assess the antimicrobial activity of the oil. Methodology The oil was incorporated in methylcellulose gel, zinc oxide pastes in addition to its application in neat form. In vivo study was conducted on puppies' premolars at 2, 4, and 6 weeks. Different w3 based agents were applied to pulp stump's for subsequent histopathological study. An in vitro antimicrobial activity of these new agents was also assessed using resazurin microtiter assay. Results The histological study revealed the following: paste and neat w3 showed less inflammation and more preservation of odontoblastic layer than gel and FC. For antimicrobial assay, Staphylococcus aureus was resistant to w3 alone at the highest tested concentration, while Streptococcus mutans and Candida albicans were sensitive to w3 combinations. Conclusions w3 is considered as a safer promising pulpotomy agent especially in paste and neat oil forms when compared to FC and it has better antibacterial effect, especially in combination with zinc oxide powder.
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