Pub Date : 2021-05-16DOI: 10.21608/EJH.2021.71326.1458
Hanan I. El-kerdasy
{"title":"Histological and Immunohistochemical Study on the Effect of Cyclophosphamide in Testis of Adult Albino Rats and the possible protective role of Vitamin E and Alpha Lipoic Acid","authors":"Hanan I. El-kerdasy","doi":"10.21608/EJH.2021.71326.1458","DOIUrl":"https://doi.org/10.21608/EJH.2021.71326.1458","url":null,"abstract":"","PeriodicalId":22420,"journal":{"name":"the egyptian journal of histology","volume":"59 1","pages":"0-0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83278965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-14DOI: 10.21608/EJH.2021.70354.1455
N. Zahran, Wafaa Ahmed, B. Mady, Melad N Kelada
ABSTRACTBackground: Osteoarthritis (OA) is a common degenerative joint disease. Intra-articular injection of microcrystalline corticosteroid and platelet- rich plasma (PRP) are used for pain relief of knee OA.Aim of the Study: the goal of this study was to assess the possible therapeutic effects of corticosteroid compared to PRP in a rat model of induced OA.Material and Methods: Intra-articular injection of monosodium iodoacetate (MIA) was used for induction of OA in rats. Blood was collected from12 adult male rats for PRP preparation. 54 adult female albino rats were divided into control groups, OA model group and treated groups which received CS or PRP. All rats were euthanized after 28 days. Left knee joints were processed for histological examination by light microscope after staining by H& E, toluidine blue and masson’s trichrome stains. Right knee joints were grossly examined by stereomicroscope and scanning electron microscope (SEM). The obtained data were examined, further statistically analyzed and interpreted. Results: MIA caused gross anatomical and histological alterations in rat’s articular cartilage similar to human knee OA. Articular cartilage of corticosteroid and PRP treated knee joints showed thinning of the articular cartilage, fibrillation and presence of pannus- like tissue. These groups also showed significant increase in histopathological scores compared to the control group and OA model group in addition to gross macroscopic changes that were confirmed by SEM.Conclusion: This study showed that neither corticosteroid nor PRP could limit the structural changes in osteoarthritis and that different PRP preparation techniques have yielded varying results.
{"title":"Effects of intra-articular corticosteroid versus platelet- rich plasma on induced knee osteoarthritis in adult albino rats. Histological and anatomical study","authors":"N. Zahran, Wafaa Ahmed, B. Mady, Melad N Kelada","doi":"10.21608/EJH.2021.70354.1455","DOIUrl":"https://doi.org/10.21608/EJH.2021.70354.1455","url":null,"abstract":"ABSTRACTBackground: Osteoarthritis (OA) is a common degenerative joint disease. Intra-articular injection of microcrystalline corticosteroid and platelet- rich plasma (PRP) are used for pain relief of knee OA.Aim of the Study: the goal of this study was to assess the possible therapeutic effects of corticosteroid compared to PRP in a rat model of induced OA.Material and Methods: Intra-articular injection of monosodium iodoacetate (MIA) was used for induction of OA in rats. Blood was collected from12 adult male rats for PRP preparation. 54 adult female albino rats were divided into control groups, OA model group and treated groups which received CS or PRP. All rats were euthanized after 28 days. Left knee joints were processed for histological examination by light microscope after staining by H& E, toluidine blue and masson’s trichrome stains. Right knee joints were grossly examined by stereomicroscope and scanning electron microscope (SEM). The obtained data were examined, further statistically analyzed and interpreted. Results: MIA caused gross anatomical and histological alterations in rat’s articular cartilage similar to human knee OA. Articular cartilage of corticosteroid and PRP treated knee joints showed thinning of the articular cartilage, fibrillation and presence of pannus- like tissue. These groups also showed significant increase in histopathological scores compared to the control group and OA model group in addition to gross macroscopic changes that were confirmed by SEM.Conclusion: This study showed that neither corticosteroid nor PRP could limit the structural changes in osteoarthritis and that different PRP preparation techniques have yielded varying results.","PeriodicalId":22420,"journal":{"name":"the egyptian journal of histology","volume":"26 1","pages":"0-0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87255478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-07DOI: 10.21608/EJH.2021.69213.1450
R. Hassan, S. Kamar, S. Marzouk, L. Rashed, E. Mohamed, Mai Goda, D. Gharib
{"title":"Microvesicles Therapy with Melatonin in Targeting Mitochondrial Dysfunction in Alzheimer's Disease Model of Female Albino Rats: Histological and Biochemical Study","authors":"R. Hassan, S. Kamar, S. Marzouk, L. Rashed, E. Mohamed, Mai Goda, D. Gharib","doi":"10.21608/EJH.2021.69213.1450","DOIUrl":"https://doi.org/10.21608/EJH.2021.69213.1450","url":null,"abstract":"","PeriodicalId":22420,"journal":{"name":"the egyptian journal of histology","volume":"4 1","pages":"0-0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75961147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-05DOI: 10.21608/EJH.2021.71830.1460
Esraa Hassan, H. Adawy, Amany A. Rabea
{"title":"Histological, Fluorescence and Ultrastructural Assessment of Presumptive Effect of Carbimazole Treatment and its Co-administration with Bone Marrow-Derived Mesenchymal Stem Cells on Parotid Glands of Albino Rats","authors":"Esraa Hassan, H. Adawy, Amany A. Rabea","doi":"10.21608/EJH.2021.71830.1460","DOIUrl":"https://doi.org/10.21608/EJH.2021.71830.1460","url":null,"abstract":"","PeriodicalId":22420,"journal":{"name":"the egyptian journal of histology","volume":"11 1","pages":"0-0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78601763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-05-03DOI: 10.21608/EJH.2021.67569.1446
S. Ahmadpour, A. Khajavi, K. Foghi
{"title":"Histological evaluation of the osteoinduction capability of demineralized human dentine implanted in the muscles of rats: A chronologic study","authors":"S. Ahmadpour, A. Khajavi, K. Foghi","doi":"10.21608/EJH.2021.67569.1446","DOIUrl":"https://doi.org/10.21608/EJH.2021.67569.1446","url":null,"abstract":"","PeriodicalId":22420,"journal":{"name":"the egyptian journal of histology","volume":"45 1","pages":"0-0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82492713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-04-24DOI: 10.21608/EJH.2021.65531.1439
A. Moawad, M. Elhindawy
{"title":"The possible protective effect of Graviola extract on salivary gland against cytotoxicity during cisplatin treatment (Histological, Biochemical and Immuno-histochemical Study)","authors":"A. Moawad, M. Elhindawy","doi":"10.21608/EJH.2021.65531.1439","DOIUrl":"https://doi.org/10.21608/EJH.2021.65531.1439","url":null,"abstract":"","PeriodicalId":22420,"journal":{"name":"the egyptian journal of histology","volume":"16 1","pages":"0-0"},"PeriodicalIF":0.0,"publicationDate":"2021-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81850015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-04-20DOI: 10.21608/EJH.2021.67224.1444
Rasha El shinety, Lobna Mohammed Abd El Mottelib, Safwat, A. El-Agwany, N. Zahran
{"title":"EFFECT OF PLATELET-RICH PLASMA IN CYCLOPHOSPHAMIDE-INDUCED OVARIAN FAILURE IN ALBINO RATS: HISTOLOGICAL AND ANATOMICAL STUDY","authors":"Rasha El shinety, Lobna Mohammed Abd El Mottelib, Safwat, A. El-Agwany, N. Zahran","doi":"10.21608/EJH.2021.67224.1444","DOIUrl":"https://doi.org/10.21608/EJH.2021.67224.1444","url":null,"abstract":"","PeriodicalId":22420,"journal":{"name":"the egyptian journal of histology","volume":"6 1","pages":"0-0"},"PeriodicalIF":0.0,"publicationDate":"2021-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78872378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-04-20DOI: 10.21608/EJH.2021.66245.1440
Noha Elswaidy, H. M. Eldin
{"title":"The Effect of Semicarbazide on the thyroid gland of Juvenile male Albino Rat and Possibility of Recovery: Histological and Immunohistochemical study","authors":"Noha Elswaidy, H. M. Eldin","doi":"10.21608/EJH.2021.66245.1440","DOIUrl":"https://doi.org/10.21608/EJH.2021.66245.1440","url":null,"abstract":"","PeriodicalId":22420,"journal":{"name":"the egyptian journal of histology","volume":"59 1","pages":"0-0"},"PeriodicalIF":0.0,"publicationDate":"2021-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84898739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-04-18DOI: 10.21608/EJH.2021.68124.1448
M. Badawi, Nermien E. Waly, M. Eid, N. Soliman
{"title":"Histopathological impact of Ginger loaded nanoparticle versus ginger extract as a novel therapy of experimentally induced acute ulcerative colitis","authors":"M. Badawi, Nermien E. Waly, M. Eid, N. Soliman","doi":"10.21608/EJH.2021.68124.1448","DOIUrl":"https://doi.org/10.21608/EJH.2021.68124.1448","url":null,"abstract":"","PeriodicalId":22420,"journal":{"name":"the egyptian journal of histology","volume":"28 1","pages":"0-0"},"PeriodicalIF":0.0,"publicationDate":"2021-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78179582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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