首页 > 最新文献

The International Journal of Life-Sciences Scientific Research最新文献

英文 中文
Chemical Characterization and Larvicidal Activity of Essential Oil from Aniba duckei Kostermans against Aedes aegypti 鸭蛤精油对埃及伊蚊的化学特性及杀幼虫活性研究
Pub Date : 2017-11-01 DOI: 10.21276/IJLSSR.2017.3.6.11
Ijlssr Journal, R. D. M. Teles, V. E. M. Filho, A. G. D. Souza
Aedes aegypti mosquito is the major vector of zika, chikungunya, and dengue fever. These diseases incidence has been growing rapidly in many points of the globe in the past few years. And because there’s no vaccine for them yet, the best way to fight those diseases is to attack their vector, specially by eliminating potential sites for its oviposition and larvae growth. Nowadays, organophosphorus insecticides are used in increasing doses, which targets Aedes aegypti resistant populations. Aniba duckei Kostermans, which is known as rosewood and belongs to the Lauraceae family, is a species with trees up to 30 meters tall and 1 meter in trunk diameter. It’s essential oil is used in perfumery due to its high content of linalool. This research identified the components of essential oil from Aniba duckei Kostermans thin branches and leaves and then applied it as larvicide against Aedes aegypti, and its effects were measured by calculation of concentration at which half larvae die (LC50). Average yield found for oil by plant was 1.93% by mass. The major component in rosewood essential oil is linalool, whose concentration was found 89.34% by mass. LC50 for the essential oil was 250.61 (±2.20) μg mL -1 , for l-linalool, 279.89 (±2.12) μg mL -1 , and for dl-linalool was 346.73 (±2.14) μg mL -1 . Key-wordsEssential oil, Aniba duckei Kostermans, Linalool, Aedes aegypti, Larvicide INTRODUCTION The world has experienced a dengue incidence increase in the last 50 years. Recent studies estimate about 395 million cases of dengue hemorrhagic fever in 100 countries, of which 500 thousand are classified as dengue hemorrhagic fever/ dengue shock syndrome (DHF / DSS) [1] . Disease is caused by four serotypes of dengue virus, DENV-1, DENV-2, DENV-3 and DENV4 [2] . This is the most important arbovirosis worldwide with about 50 million infections per year [3] , and it can be asymptomatic or manifest many symptoms, from self-limited febrile illness to severe forms that may lead to death [4] . In terms of morbidity and mortality, dengue is nowadays considered the most important viral disease transmitted by mosquitoes, constituting a serious public health problem of urban centers from South & Central America, Access this article online Quick Response Code Website:
埃及伊蚊是寨卡病毒、基孔肯雅热和登革热的主要媒介。在过去几年中,这些疾病的发病率在全球许多地方迅速增长。因为目前还没有针对它们的疫苗,所以对抗这些疾病的最好方法是攻击它们的载体,特别是通过消除其产卵和幼虫生长的潜在场所。如今,有机磷杀虫剂的使用剂量越来越大,其目标是埃及伊蚊抗性种群。紫檀木(Aniba duckei Kostermans)属于樟科,被称为紫檀木,树高可达30米,树干直径1米。它的精油因其高含量的芳樟醇而被用于香水。本研究鉴定了鸭竹细枝细叶精油的主要成分,并将其作为杀蚊剂应用于埃及伊蚊,通过计算半数幼虫死亡浓度(LC50)来测定其药效。平均产油率为1.93%(质量比)。红木精油的主要成分为芳樟醇,其质量浓度为89.34%。精油LC50为250.61(±2.20)μ mL -1, l-芳樟醇LC50为279.89(±2.12)μ mL -1, dl-芳樟醇LC50为346.73(±2.14)μ mL -1。【关键词】精油,紫檀香,芳樟醇,埃及伊蚊,杀幼虫剂引言在过去的50年里,全世界的登革热发病率呈上升趋势。最近的研究估计,100个国家约有3.95亿登革热出血热病例,其中50万例被列为登革出血热/登革休克综合征(DHF / DSS)。该病由四种血清型登革热病毒(DENV-1、DENV-2、DENV-3和DENV4[2])引起。这是世界上最重要的虫媒病毒病,每年约有5000万例感染bb1,它可以无症状或表现出许多症状,从自限性发热疾病到可能导致死亡的严重形式bb1。就发病率和死亡率而言,登革热目前被认为是由蚊子传播的最重要的病毒性疾病,构成了南美洲和中美洲城市中心的严重公共卫生问题。
{"title":"Chemical Characterization and Larvicidal Activity of Essential Oil from Aniba duckei Kostermans against Aedes aegypti","authors":"Ijlssr Journal, R. D. M. Teles, V. E. M. Filho, A. G. D. Souza","doi":"10.21276/IJLSSR.2017.3.6.11","DOIUrl":"https://doi.org/10.21276/IJLSSR.2017.3.6.11","url":null,"abstract":"Aedes aegypti mosquito is the major vector of zika, chikungunya, and dengue fever. These diseases incidence has been growing rapidly in many points of the globe in the past few years. And because there’s no vaccine for them yet, the best way to fight those diseases is to attack their vector, specially by eliminating potential sites for its oviposition and larvae growth. Nowadays, organophosphorus insecticides are used in increasing doses, which targets Aedes aegypti resistant populations. Aniba duckei Kostermans, which is known as rosewood and belongs to the Lauraceae family, is a species with trees up to 30 meters tall and 1 meter in trunk diameter. It’s essential oil is used in perfumery due to its high content of linalool. This research identified the components of essential oil from Aniba duckei Kostermans thin branches and leaves and then applied it as larvicide against Aedes aegypti, and its effects were measured by calculation of concentration at which half larvae die (LC50). Average yield found for oil by plant was 1.93% by mass. The major component in rosewood essential oil is linalool, whose concentration was found 89.34% by mass. LC50 for the essential oil was 250.61 (±2.20) μg mL -1 , for l-linalool, 279.89 (±2.12) μg mL -1 , and for dl-linalool was 346.73 (±2.14) μg mL -1 . Key-wordsEssential oil, Aniba duckei Kostermans, Linalool, Aedes aegypti, Larvicide INTRODUCTION The world has experienced a dengue incidence increase in the last 50 years. Recent studies estimate about 395 million cases of dengue hemorrhagic fever in 100 countries, of which 500 thousand are classified as dengue hemorrhagic fever/ dengue shock syndrome (DHF / DSS) [1] . Disease is caused by four serotypes of dengue virus, DENV-1, DENV-2, DENV-3 and DENV4 [2] . This is the most important arbovirosis worldwide with about 50 million infections per year [3] , and it can be asymptomatic or manifest many symptoms, from self-limited febrile illness to severe forms that may lead to death [4] . In terms of morbidity and mortality, dengue is nowadays considered the most important viral disease transmitted by mosquitoes, constituting a serious public health problem of urban centers from South & Central America, Access this article online Quick Response Code Website:","PeriodicalId":22509,"journal":{"name":"The International Journal of Life-Sciences Scientific Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83535807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Biochemical Markers of Oxidative Stress in Brain of Zebrafish Danio rerio Exposed to Different Heavy Metals Lead and Cobalt 不同重金属铅、钴对斑马鱼脑氧化应激生化标志物的影响
Pub Date : 2017-11-01 DOI: 10.21276/IJLSSR.2017.3.6.10
C. Singh, B. Ansari
Aquatic organisms have been considered to concentrate metals several times greater than environmental levels. Fishes have been used for many decades to evaluate the pollution status of water and thus considered as excellent biological indicator of heavy metals in aquatic environments. Heavy metals are natural tress components of the aquatic environment, but their levels have increased due to domestic, industrial, mining and agricultural activities. These heavy metals when accumulated in the fish tissues, they damage and weaken the mechanisms concerned leading to physiological, pathological and biochemical changes. The lead is non essential element while cobalt is an essential element for living organisms but its presence in fresh water in higher concentration are toxic to organism’s brain, liver, ovary, kidney and gills of the fish. The present study was aimed to investigate the changes due to two heavy metals (lead & cobalt) on the activity of the antioxidant enzyme, Catalase (CAT), Reduced glutathione (GSH), and Lipid peroxidation (LPO) in the brain of Danio rerio during 5, 10, 15 and 20 days of exposure period. For this study adult fishes were exposed to four different concentrations viz., 20, 30, 40 and 50 mg/l of cobalt and 5, 9, 13, and 17 mg/l of lead. Key-wordsZebrafish, Lead, Cobalt, Catalase, LPO, Glutathione, Heavy metals INTRODUCTION Heavy metals are produced from a variety of natural and anthropogenic sources [1] . In aquatic environments, heavy metal pollution results from direct atmospheric deposition, geologic weathering or through the discharge of agricultural, municipal, residential or industrial waste products, also via wastewater treatment plants [2-4] . The contamination of heavy metals and metalloids in water and sediment, when occurring in higher concentrations, is a serious threat because of their toxicity, long persistence, and bioaccumulation and bio magnification in the food chain [5] . Generally, metals can be categorized as biologically essential and non-essential. The nonessential metals for example, aluminum (Al), cadmium (Cd), mercury (Hg), tin (Sn) and lead (Pb) have no proven biological function also called xenobiotics or foreign elements and their toxicity rises with increasing concentrations [6] . Essential metals for example, copper (Cu), zinc (Zn), chromium (Cr), nickel (Ni), cobalt (Co), Molybdenum (Mo) and iron (Fe) on the other hand, have Access this article online Quick Response Code Website: www.ijlssr.com DOI: 10.21276/ijlssr.2017.3.6.10 known important biological roles [7] , and toxicity occurs either at metabolic deficiencies or at high concentrations [8] . The deficiency of an essential metal can therefore cause an adverse health effect, whereas its high concentration can also result in negative impacts which are equivalent to or worse than those caused by non-essential metals [9] . The river system may be extremely contaminated with heavy metals released from domestic, industrial, mining and agricul
人们认为,水生生物对金属的富集程度是环境水平的数倍。几十年来,鱼类一直被用来评价水体污染状况,因此被认为是水生环境中重金属的优秀生物指标。重金属是水生环境的天然组成部分,但由于家庭、工业、采矿和农业活动,其水平有所增加。当这些重金属在鱼类组织中积累时,它们会破坏和削弱相关机制,导致生理、病理和生化变化。铅是生物体的非必需元素,而钴是生物体的必需元素,但其在淡水中高浓度存在对生物体的脑、肝、卵巢、肾和鱼鳃都有毒性。本研究旨在探讨两种重金属(铅和钴)在暴露5、10、15和20 d期间对斑马鱼大脑中过氧化氢酶(CAT)、还原性谷胱甘肽(GSH)和脂质过氧化(LPO)活性的影响。在这项研究中,成年鱼暴露于四种不同浓度的钴,即20、30、40和50毫克/升,以及5、9、13和17毫克/升的铅。关键词斑马鱼,铅,钴,过氧化氢酶,LPO,谷胱甘肽,重金属介绍重金属的产生有多种自然和人为来源[1]。在水生环境中,重金属污染来自直接的大气沉降、地质风化或农业、市政、住宅或工业废物的排放,也来自废水处理厂[2-4]。水和沉积物中重金属和类金属的污染,由于其毒性、持久性和在食物链中的生物积累和生物放大作用,当其浓度较高时,是一个严重的威胁[5]。一般来说,金属可分为生物必需和非必需两类。非必需金属如铝(Al)、镉(Cd)、汞(Hg)、锡(Sn)和铅(Pb)等没有被证实的生物学功能,也被称为异种或外来元素,其毒性随着浓度的增加而增加[6]。另一方面,铜(Cu)、锌(Zn)、铬(Cr)、镍(Ni)、钴(Co)、钼(Mo)和铁(Fe)等必需金属具有已知的重要生物作用[7],毒性发生在代谢不足或高浓度[8]。因此,缺乏一种必需金属会对健康造成不利影响,而其高浓度也会造成与非必需金属相当或更严重的负面影响[9]。河流系统可能受到家庭、工业、采矿和农业废水排放的重金属的严重污染。重金属污染可能对接收环境的生态平衡和水生生物多样性产生干扰影响[10-11]。在动物物种中,鱼类是无法逃脱这些污染物的有害影响的居民[12]。金属以及其他污染物对水生生物群的影响可以通过毒性试验来评价,毒性试验用于检测和评价化学品对水生生物的潜在毒理学影响。然而,关于污染对热带生态系统影响的研究很少[13]。鱼类被广泛用于评估水生生态系统的健康,因为污染物在食物链中积累,并对水生系统的不利影响和死亡负责。鱼类可以通过鳃直接从水中获取微量元素,也可以通过消化道间接从食物中获取微量元素[14]。重金属因其持久的性质、易中毒的倾向而被认为是一种强的生物毒物。j .生活。科学。Scienti。科学研究学报,3(6):1484-1494 2017年11月版权所有©2015-2017| IJLSSR由美国科学研究学会授权CC by - nc 4.0国际许可Page 1485获取[15],它们在生物体内积累并经过食物链扩增,也对水生动物造成损害。在过去的几十年里,各种各样的污染物对淡水的污染已经成为一个令人非常关注的问题。铅是一种持久性金属,通常用于各种工业过程中。它对生命系统有毒,由于其持久性,可能会在环境中停留很长一段时间;它以游离金属的形式存在于各种化合物中。铅是一种广泛存在的环境和职业外源性物质,对人类和各种生态系统都有危害[16]。其对人类的暴露主要是通过口食和大气中的烟雾和粉尘吸入[17]。 由于铅的广泛使用,铅的暴露主要来自人为来源。铅的存在形式决定了它在环境中的毒性。一些研究将无机铅(如醋酸铅化合物)与各种生物体疾病发病率的增加联系起来。铅毒性与神经系统疾病、高血压、认知障碍等的发病率有关[18]。Chen等人[19]报道,将低剂量的发育铅暴露于斑马鱼胚胎会导致斑马鱼胚胎毒性、行为改变和成年学习/记忆缺陷。它在沉积物中的积累对水生生物具有重要意义。它不是过渡金属,不容易发生价态变化,它可以通过直接作用于细胞膜,铅与血红蛋白相互作用,增加血红蛋白的自氧化,自氧化的δ-氨基乙酰丙酸,与谷胱甘肽还原酶相互作用,或通过与硒形成复合物,降低谷胱甘肽过氧化物酶的活性来诱导氧化损伤[20]。铅沉积在鱼的肝脏、大脑、肾脏、脾脏、消化道和鳃等器官中[21]。钴是人体必需的营养物质,是维生素B12的组成部分。它具有重要的生化功能,但其在水生生态系统中的较高浓度会干扰酶系统,从而对鱼类产生毒性[22]。据报道,它是一种潜在的致癌化合物,最近被列入2A类致癌物,即可能对人类致癌。钴可以通过鱼鳃从周围的水中吸收,也可以从食物中吸收。随着温度的升高,水性钴的吸收量增加,水性钙的吸收量减少。此外,已知重金属通过介导自由基(如活性氧)诱导氧化应激和致癌[23]。它们消耗谷胱甘肽,导致活性氧(ROS)如过氧化氢酶的产生增强。活性氧被认为是金属引发的组织损伤和细胞凋亡的重要介质。为了防止氧化引起的损伤,必须有有效的抗氧化系统酶,包括自由基清除酶,如超氧化物歧化酶(SOD)和过氧化氢酶(CAT),改变酶的活性等生物标志物是水生毒理学研究的可能工具[24]。斑马鱼可作为环境污染的生物指示物。材料与方法本研究于2017年4月在印度戈拉克布尔D.D.U.戈拉克布尔大学动物学系斑马鱼实验室进行。收集国际标准化组织(IOS, 1976)[25]和经济合作与发展组织(OECD)[26]推荐的斑马鱼,驯化一个月,在实验室条件下放养。水族箱通过连接机械空气压缩机的石头扩散器连续充气,水温保持在25±2℃,鱼每天两次交替投喂生的和切碎的羊肝和虾粉。补充从宠物店购买的管虫、四甲虫和螺旋藻颗粒。在本研究中,研究人员从水族馆中获取了长约3.5厘米、重约1克的成年斑马鱼,并将其暴露于四种不同浓度的环境中,即20、30、40和50 mg/l的钴和05.00、09.00、13.00和17.00 mg/l的铅,这些浓度是根据我们之前的毒性测试计算出来的。根据Singh和Ansari[27]的早期计算,当暴露低于80% 96-h LC50范围时,判定重金属浓度。选择低浓度是因为鱼类可以在毒物的胁迫下存活。每种浓度下分别有20条鱼。水族馆里的水每天都用新处理过的金属代替。每个实验都有各自的对照。在5、10、15和20天的暴露期后,从实验组和对照组中取出所需数量的处理鱼。他们的大脑被移除并处理。生化测定CAT (EC 1.11.1.6)活性根据Sinha[28]的程序进行估计。这种方法是基于这样一个事实,即在醋酸中,重铬酸盐在H2O2存在下加热时会还原为醋酸铬,形成高铬酸作为不稳定的中间体。用比色法在620nm处测定醋酸铬。过氧化氢酶制剂通过加入二色乙酸混合物,在不同的时间间隔使H2O2分裂,剩余的H2O2用比色法测定。结果表示为μM H2O2利用/min/mg蛋白。脑内谷胱甘肽(GSH)含量根据Paglia等[29]的方法估算。组织(脑)溶解2。
{"title":"Biochemical Markers of Oxidative Stress in Brain of Zebrafish Danio rerio Exposed to Different Heavy Metals Lead and Cobalt","authors":"C. Singh, B. Ansari","doi":"10.21276/IJLSSR.2017.3.6.10","DOIUrl":"https://doi.org/10.21276/IJLSSR.2017.3.6.10","url":null,"abstract":"Aquatic organisms have been considered to concentrate metals several times greater than environmental levels. Fishes have been used for many decades to evaluate the pollution status of water and thus considered as excellent biological indicator of heavy metals in aquatic environments. Heavy metals are natural tress components of the aquatic environment, but their levels have increased due to domestic, industrial, mining and agricultural activities. These heavy metals when accumulated in the fish tissues, they damage and weaken the mechanisms concerned leading to physiological, pathological and biochemical changes. The lead is non essential element while cobalt is an essential element for living organisms but its presence in fresh water in higher concentration are toxic to organism’s brain, liver, ovary, kidney and gills of the fish. The present study was aimed to investigate the changes due to two heavy metals (lead & cobalt) on the activity of the antioxidant enzyme, Catalase (CAT), Reduced glutathione (GSH), and Lipid peroxidation (LPO) in the brain of Danio rerio during 5, 10, 15 and 20 days of exposure period. For this study adult fishes were exposed to four different concentrations viz., 20, 30, 40 and 50 mg/l of cobalt and 5, 9, 13, and 17 mg/l of lead. Key-wordsZebrafish, Lead, Cobalt, Catalase, LPO, Glutathione, Heavy metals INTRODUCTION Heavy metals are produced from a variety of natural and anthropogenic sources [1] . In aquatic environments, heavy metal pollution results from direct atmospheric deposition, geologic weathering or through the discharge of agricultural, municipal, residential or industrial waste products, also via wastewater treatment plants [2-4] . The contamination of heavy metals and metalloids in water and sediment, when occurring in higher concentrations, is a serious threat because of their toxicity, long persistence, and bioaccumulation and bio magnification in the food chain [5] . Generally, metals can be categorized as biologically essential and non-essential. The nonessential metals for example, aluminum (Al), cadmium (Cd), mercury (Hg), tin (Sn) and lead (Pb) have no proven biological function also called xenobiotics or foreign elements and their toxicity rises with increasing concentrations [6] . Essential metals for example, copper (Cu), zinc (Zn), chromium (Cr), nickel (Ni), cobalt (Co), Molybdenum (Mo) and iron (Fe) on the other hand, have Access this article online Quick Response Code Website: www.ijlssr.com DOI: 10.21276/ijlssr.2017.3.6.10 known important biological roles [7] , and toxicity occurs either at metabolic deficiencies or at high concentrations [8] . The deficiency of an essential metal can therefore cause an adverse health effect, whereas its high concentration can also result in negative impacts which are equivalent to or worse than those caused by non-essential metals [9] . The river system may be extremely contaminated with heavy metals released from domestic, industrial, mining and agricul","PeriodicalId":22509,"journal":{"name":"The International Journal of Life-Sciences Scientific Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91186833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Effect of Heavy Metals on the Activity Levels of Hepatic Enzymes in the Maternal and Embryonic Tissues of Viviparous Scorpion (H. fulvipes) 重金属对胎生蝎母体和胚胎组织肝酶活性的影响
Pub Date : 2017-11-01 DOI: 10.21276/IJLSSR.2017.3.6.3
M. Rao, Y. Acharya, S. JitenderKumarNaik, Samir Fatteh, Amin Fateh, Anusha C. Pawar, G. Jayalakshmi, B. Sandhya, A. Sireeshabala
An experimental study was performed with viviparous animal Heterometrous fulvipes to access the cumulative effect of chronic heavy metals exposure on the activity levels of the enzymes aspartate aminotransferase (AST) and alanine aminotransferase (ALT). Chronic heavy metal exposure resulted in variation in the enzymes levels with increase in AST and decreases in ALT, contributed to the stress induced by the heavy metals. These changes in enzymatic activity of the maternal and embryonic tissue of H. fulvipes under the influence of heavy metal, mercury and lead is suggestive of the specific impact of mercury and lead on the enzymatic pathway, prompting a further study to consolidate the finding in human study. It is pertinent that the heavy metal toxicity be well documented and appropriate precaution taken in mother and fetus to decrease its detrimental effects. Key-wordsHeavy Metals, Animal models, Hepatic Enzymes, Viviparous INTRODUCTION Heavy metals are believed to exert their influence on the activity of the enzymes playing a vital role in the biochemical transactions of a living system. Embryonic development is characterized by growth and formation of new tissues. The alterations in the activity of enzymes and/or embryonic tissues would invariably influence the developmental processes in viviparous animals as embryonic nourishment is provided by the maternal sources. Shift in the metabolism of either the maternal tissues or the embryos owing to changes in the enzyme activity influenced by heavy metals can be reflected in the form of deviations from the normal development. The metabolic levels of the embryo can, therefore, be expected to be different from those of the maternal animal. The metabolic state of the embryo relative to that of the mother would be reflected even at the molecular level in the enzymatic activity. Access this article online Quick Response Code Website:
以胎生异长尾猴为实验对象,研究了慢性重金属暴露对其谷草转氨酶(AST)和丙氨酸转氨酶(ALT)活性水平的累积效应。慢性重金属暴露导致酶水平变化,AST升高,ALT降低,导致重金属胁迫。在重金属、汞和铅的影响下,黄颡鱼母体和胚胎组织酶活性的这些变化提示了汞和铅对酶途径的特异性影响,需要进一步的研究来巩固人类研究的发现。因此,应充分记录重金属的毒性,并在母体和胎儿中采取适当的预防措施,以减少其有害影响。重金属,动物模型,肝酶,胎生INTRODUCTION重金属被认为会影响在生命系统生化交易中起重要作用的酶的活性。胚胎发育的特点是新组织的生长和形成。酶和/或胚胎组织活性的改变必然会影响胎生动物的发育过程,因为胚胎营养是由母体提供的。由于受重金属影响的酶活性的变化而引起母体组织或胚胎代谢的变化,可以以偏离正常发育的形式反映出来。因此,胚胎的代谢水平可以预期与母畜的代谢水平不同。胚胎相对于母体的代谢状态甚至在酶活性的分子水平上也能反映出来。在线阅读本文快速响应代码网站:
{"title":"Effect of Heavy Metals on the Activity Levels of Hepatic Enzymes in the Maternal and Embryonic Tissues of Viviparous Scorpion (H. fulvipes)","authors":"M. Rao, Y. Acharya, S. JitenderKumarNaik, Samir Fatteh, Amin Fateh, Anusha C. Pawar, G. Jayalakshmi, B. Sandhya, A. Sireeshabala","doi":"10.21276/IJLSSR.2017.3.6.3","DOIUrl":"https://doi.org/10.21276/IJLSSR.2017.3.6.3","url":null,"abstract":"An experimental study was performed with viviparous animal Heterometrous fulvipes to access the cumulative effect of chronic heavy metals exposure on the activity levels of the enzymes aspartate aminotransferase (AST) and alanine aminotransferase (ALT). Chronic heavy metal exposure resulted in variation in the enzymes levels with increase in AST and decreases in ALT, contributed to the stress induced by the heavy metals. These changes in enzymatic activity of the maternal and embryonic tissue of H. fulvipes under the influence of heavy metal, mercury and lead is suggestive of the specific impact of mercury and lead on the enzymatic pathway, prompting a further study to consolidate the finding in human study. It is pertinent that the heavy metal toxicity be well documented and appropriate precaution taken in mother and fetus to decrease its detrimental effects. Key-wordsHeavy Metals, Animal models, Hepatic Enzymes, Viviparous INTRODUCTION Heavy metals are believed to exert their influence on the activity of the enzymes playing a vital role in the biochemical transactions of a living system. Embryonic development is characterized by growth and formation of new tissues. The alterations in the activity of enzymes and/or embryonic tissues would invariably influence the developmental processes in viviparous animals as embryonic nourishment is provided by the maternal sources. Shift in the metabolism of either the maternal tissues or the embryos owing to changes in the enzyme activity influenced by heavy metals can be reflected in the form of deviations from the normal development. The metabolic levels of the embryo can, therefore, be expected to be different from those of the maternal animal. The metabolic state of the embryo relative to that of the mother would be reflected even at the molecular level in the enzymatic activity. Access this article online Quick Response Code Website:","PeriodicalId":22509,"journal":{"name":"The International Journal of Life-Sciences Scientific Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82712398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Review on Beetles (Coleopteran): An Agricultural Major Crop Pests of the World 甲虫(鞘翅目):世界主要的农业作物害虫
Pub Date : 2017-11-01 DOI: 10.21276/IJLSSR.2017.3.6.1
Dr. S. S. Patole
The present review deals on major Coleopteran beetles of agricultural crop pests include 45 genera and 55 species from 15 families. Most of beetles are pest of cereals and millets (3), oil seed crops (2), fibre crops (4), vegetables (11), temperate fruits (7), sub-tropical and tropical fruits (9), ornamental plants (2), plantation crop (8), spices (4) and stored grains (5). Among families; Curculionidae was dominated by 12 (21.8 %) species followed by Chrysomelidae 10(18.18 %), Cerambycidae 9(16.3 %), Scarabaeridae 6(10.9 %), Coccinellidae 3(5.4 %), Apionidae, Bostrychidae, Brachidae, Buprestidae and Scolytidae each with two species (3.6 %). Whereas families like Dermestidae, Lamiidae, Meloidae, Melonithidae and Tenebrionidae contribute each with single species (1.8 %). Key-wordsColeopteran beetle, Cereals, Spices, Stored grains, temperate fruits. INTRODUCTION The coleopterans include more species than any other order, constituting almost 25 % of all known types of animal life forms [1] . About 4, 50,000 species of beetles occurs representing about 40 % of all known insects [2] . Such a large number of species poses special problems for classification. Among them, about 75 % of beetle species are polyphagous in both larval and adult stages, and live in or on plants, wood as well as a variety of stored products [3-4]. Because many of these plants are important for agriculture, forestry and the household, beetles can be considered pest and some of them cause significant damage, particularly direct and indirect losses [5] . There are several studies on different families of coleopteran by different research workers [6-7] . The pest problems originated with the origin of agriculture. As soon as the land was cleared of natural vegetation and replaced by a single species of food plant, human came into conflict with phytophagous insect [8-9] . It was reported that the insect pest problems in agriculture are probably as old as agriculture itself [10] . However, rapidly increasing population during the last century has necessitated intensification of agriculture through expansion of irrigation facilities, introduction of high yielding varieties (HYVs) and application of increased amount of agrochemicals increased the production of land with a concomitant increase in the production lost to insect pest [11-12] . Access this article online Quick Response Code Website:
本文综述了主要害虫鞘翅目甲虫15科45属55种。大多数甲虫是谷物和小米(3),油料作物(2),纤维作物(4),蔬菜(11),温带水果(7),亚热带和热带水果(9),观赏植物(2),种植园作物(8),香料(4)和储存谷物(5)的害虫。以屈曲蝇科12种(21.8%)为主,其次为金曲蝇科10种(18.18%)、天牛科9种(16.3%)、金龟甲科6种(10.9%)、瓢虫科3种(5.4%)、蜂蝇科、竹蝇科、腕足科、布氏蝇科和棘蝇科各2种(3.6%)。而皮蝇科、绵蝇科、绵蝇科、黑蝇科和拟甲科各有1种(1.8%)。【关键词】鞘翅目甲虫;谷物;香料;鞘翅目的种类比其他任何目都要多,几乎占所有已知动物生命形式类型的25%[1]。甲虫约有45万种,约占所有已知昆虫的40%[2]。如此多的物种给分类带来了特殊的问题。其中,约75%的甲虫在幼虫期和成虫期都是多食性的,生活在植物、木材以及各种储藏物中或表面[3-4]。由于这些植物中的许多对农业、林业和家庭都很重要,因此甲虫可被视为有害生物,其中一些造成重大损害,特别是直接和间接损失[5]。不同的研究者对不同科的鞘翅目进行了多项研究[6-7]。害虫问题起源于农业的起源。一旦土地上的自然植被被清除,取而代之的是单一的食用植物,人类就与食植物昆虫发生了冲突[8-9]。据报道,农业中的害虫问题可能与农业本身一样古老[10]。然而,上个世纪人口的迅速增长使得农业集约化成为必要,通过扩大灌溉设施、引进高产品种(hyv)和增加农用化学品的使用,增加了土地产量,同时也增加了虫害造成的产量损失[11-12]。在线阅读本文快速响应代码网站:
{"title":"Review on Beetles (Coleopteran): An Agricultural Major Crop Pests of the World","authors":"Dr. S. S. Patole","doi":"10.21276/IJLSSR.2017.3.6.1","DOIUrl":"https://doi.org/10.21276/IJLSSR.2017.3.6.1","url":null,"abstract":"The present review deals on major Coleopteran beetles of agricultural crop pests include 45 genera and 55 species from 15 families. Most of beetles are pest of cereals and millets (3), oil seed crops (2), fibre crops (4), vegetables (11), temperate fruits (7), sub-tropical and tropical fruits (9), ornamental plants (2), plantation crop (8), spices (4) and stored grains (5). Among families; Curculionidae was dominated by 12 (21.8 %) species followed by Chrysomelidae 10(18.18 %), Cerambycidae 9(16.3 %), Scarabaeridae 6(10.9 %), Coccinellidae 3(5.4 %), Apionidae, Bostrychidae, Brachidae, Buprestidae and Scolytidae each with two species (3.6 %). Whereas families like Dermestidae, Lamiidae, Meloidae, Melonithidae and Tenebrionidae contribute each with single species (1.8 %). Key-wordsColeopteran beetle, Cereals, Spices, Stored grains, temperate fruits. INTRODUCTION The coleopterans include more species than any other order, constituting almost 25 % of all known types of animal life forms [1] . About 4, 50,000 species of beetles occurs representing about 40 % of all known insects [2] . Such a large number of species poses special problems for classification. Among them, about 75 % of beetle species are polyphagous in both larval and adult stages, and live in or on plants, wood as well as a variety of stored products [3-4]. Because many of these plants are important for agriculture, forestry and the household, beetles can be considered pest and some of them cause significant damage, particularly direct and indirect losses [5] . There are several studies on different families of coleopteran by different research workers [6-7] . The pest problems originated with the origin of agriculture. As soon as the land was cleared of natural vegetation and replaced by a single species of food plant, human came into conflict with phytophagous insect [8-9] . It was reported that the insect pest problems in agriculture are probably as old as agriculture itself [10] . However, rapidly increasing population during the last century has necessitated intensification of agriculture through expansion of irrigation facilities, introduction of high yielding varieties (HYVs) and application of increased amount of agrochemicals increased the production of land with a concomitant increase in the production lost to insect pest [11-12] . Access this article online Quick Response Code Website:","PeriodicalId":22509,"journal":{"name":"The International Journal of Life-Sciences Scientific Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90773657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Prevalence of Tuberculosis: Present Status and Overview of Its Control System in Bangladesh 结核病的流行:孟加拉国结核病控制系统的现状和概况
Pub Date : 2017-11-01 DOI: 10.21276/IJLSSR.2017.3.6.8
Md. Samiul Islam, R. Sultana, Md. Amit Hasan, Md Abu Horaira, Md. Azizul Islam
{"title":"Prevalence of Tuberculosis: Present Status and Overview of Its Control System in Bangladesh","authors":"Md. Samiul Islam, R. Sultana, Md. Amit Hasan, Md Abu Horaira, Md. Azizul Islam","doi":"10.21276/IJLSSR.2017.3.6.8","DOIUrl":"https://doi.org/10.21276/IJLSSR.2017.3.6.8","url":null,"abstract":"","PeriodicalId":22509,"journal":{"name":"The International Journal of Life-Sciences Scientific Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89063885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Evaluation of Knowledge, Attitude and Practice of Transcendental Meditation in Pregnant Women 孕妇超觉静坐知识、态度与练习之评估
Pub Date : 2017-11-01 DOI: 10.21276/IJLSSR.2017.3.6.6
Kalpana V Jaiswal, Kavita M. Jaiswal, K. J. Jaiswal, Jagdish Jaiswal
Background: Transcendental Meditation (TM) promotes a state of relaxation. It has been reported in vedic literature that practicing TM during pregnancy has health benefits .There is a paucity of data regarding use to TM by pregnant women. Objective: The aim was to determine the knowledge, attitudes, and practice toward TM among pregnant women. Materials and Methods: This was a prospective, cross-sectional, observational, questionnaire-based study conducted in 100 antenatal women attending private nursing homes for their antenatal care. Results: Among the respondents, 32% were aware of TM and 22% practiced it during their current pregnancy, 15% practised it under a TM instructor. The time schedule followed by respondents was as follows, 15 women practised it for 20 min a day, 3 practised for 10 min a day, rest didn’t follow the schedule. Thirty percent respondents felt that TM was based on scientific evidence, while 25% felt it was safer than other relaxation techniques that is significantly more in women educated up-to or more than 12 th std. Twenty-five percent opined that TM is more efficacious than other relaxation techniques which is significantly more in working women. Relaxation of body and mind, easy to practice, were the most common advantages of practising TM during pregnancy. The main source of information about TM was internet and social media. Conclusion: Awareness about TM is less and so is the practice in the pregnant women. The importance of practising TM during pregnancy needs to be addressed. This will help the mothers to have healthy pregnancy and out-come. Key-wordsRelaxation techniques, Antenatal women, Questionnaire based study, Transcendental Meditation (TM) INTRODUCTION Ayurveda (Science of Life) is the comprehensive, natural health care system that originated in the ancient Vedic times of India [1] . According to Vedic science the true purpose of meditation is to connect oneself to one’s deep inner self. Techniques which achieve that goal serve the true purpose of meditation. According to Ayurveda the human body constitutes of three components, with their associated functions: Physical bodySthula sarira-gross body Inner facultyThe Inner faculty is the working consciousness, which is constantly changing and consists of: Access this article online Quick Response Code Website:
背景:超越冥想(TM)促进一种放松状态。据吠陀文献报道,在怀孕期间练习超觉静坐对健康有益,但关于孕妇使用超觉静坐的数据很少。目的:了解孕妇对TM的认知、态度和行为。材料和方法:这是一项前瞻性的、横断面的、观察性的、基于问卷的研究,对100名在私人疗养院接受产前护理的产前妇女进行了研究。结果:32%的受访者知道TM, 22%的人在怀孕期间进行了TM练习,15%的人在TM教练的指导下进行了TM练习。被调查者遵循的时间安排如下,15名女性每天练习20分钟,3名女性每天练习10分钟,其余女性不遵循时间安排。30%的受访者认为超觉静坐是基于科学证据的,而25%的受访者认为超觉静坐比其他放松技术更安全,这在受过12年级以上教育的女性中更为普遍。25%的受访者认为超觉静坐比其他放松技术更有效,这在职业女性中更为普遍。身心放松,容易练习,是在怀孕期间练习TM最常见的优点。TM的主要信息来源是网络和社交媒体。结论:孕妇对TM的认知度较低,实践较少。在怀孕期间练习冥想的重要性需要得到重视。这将有助于母亲有一个健康的怀孕和结果。阿育吠陀(生命的科学)是一门综合性的、自然的保健体系,起源于印度古吠陀时代。根据吠陀科学,冥想的真正目的是将自己与内心深处的自我联系起来。达到这个目标的技巧服务于冥想的真正目的。根据阿育吠陀的说法,人体由三个部分组成,并具有相关的功能:身体,修罗,全身,内在能力内在能力是工作意识,它是不断变化的,包括:
{"title":"Evaluation of Knowledge, Attitude and Practice of Transcendental Meditation in Pregnant Women","authors":"Kalpana V Jaiswal, Kavita M. Jaiswal, K. J. Jaiswal, Jagdish Jaiswal","doi":"10.21276/IJLSSR.2017.3.6.6","DOIUrl":"https://doi.org/10.21276/IJLSSR.2017.3.6.6","url":null,"abstract":"Background: Transcendental Meditation (TM) promotes a state of relaxation. It has been reported in vedic literature that practicing TM during pregnancy has health benefits .There is a paucity of data regarding use to TM by pregnant women. Objective: The aim was to determine the knowledge, attitudes, and practice toward TM among pregnant women. Materials and Methods: This was a prospective, cross-sectional, observational, questionnaire-based study conducted in 100 antenatal women attending private nursing homes for their antenatal care. Results: Among the respondents, 32% were aware of TM and 22% practiced it during their current pregnancy, 15% practised it under a TM instructor. The time schedule followed by respondents was as follows, 15 women practised it for 20 min a day, 3 practised for 10 min a day, rest didn’t follow the schedule. Thirty percent respondents felt that TM was based on scientific evidence, while 25% felt it was safer than other relaxation techniques that is significantly more in women educated up-to or more than 12 th std. Twenty-five percent opined that TM is more efficacious than other relaxation techniques which is significantly more in working women. Relaxation of body and mind, easy to practice, were the most common advantages of practising TM during pregnancy. The main source of information about TM was internet and social media. Conclusion: Awareness about TM is less and so is the practice in the pregnant women. The importance of practising TM during pregnancy needs to be addressed. This will help the mothers to have healthy pregnancy and out-come. Key-wordsRelaxation techniques, Antenatal women, Questionnaire based study, Transcendental Meditation (TM) INTRODUCTION Ayurveda (Science of Life) is the comprehensive, natural health care system that originated in the ancient Vedic times of India [1] . According to Vedic science the true purpose of meditation is to connect oneself to one’s deep inner self. Techniques which achieve that goal serve the true purpose of meditation. According to Ayurveda the human body constitutes of three components, with their associated functions: Physical bodySthula sarira-gross body Inner facultyThe Inner faculty is the working consciousness, which is constantly changing and consists of: Access this article online Quick Response Code Website:","PeriodicalId":22509,"journal":{"name":"The International Journal of Life-Sciences Scientific Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86415128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
An Assessment of Awareness, Barriers in Perception of Cervical Cancer and Effect Estimation of Educational Intervention Programme in Females 女性宫颈癌认知、认知障碍及教育干预方案效果评估
Pub Date : 2017-11-01 DOI: 10.21276/IJLSSR.2017.3.6.15
Ashwini G. Darokar, R. Patil, Amol Patel, M. Nivetha
Background: Women of all races and ethnicities are at risk of cervical cancer. India, around 0.95 million new cases are detected yearly with high burden of 0.63 million. India bears about one fifth of the world’s burden of cervical cancer. Although fatality is high but cancers are largely preventable by effective screening programmes. Design: The present quasi-experimental study was conducted among female students studying in degree colleges from Feb. 2013 to Sept. 2013. Intervention: Educational intervention was conducted through sessions of participatory learning approach which included lectures using power-point, chalk and talk and question-answers method. Data was collected twice by administering predesigned questionnaire and conducting focus group discussion. Data Analysis: Data entered and analyzed using Epi Info 2000. To analyze qualitative information Atlas ti software was used. Paired t-test was used to measure the effect of intervention. Results: Total 149 students were the part of the study and successfully followed. Mean age of the participant was 18.5 years. Out of the 149 participants 4.1% had family history of the cancer. In the study it was observed that 18.8% had not ever heard about the cancer. In the post intervention test significant improvement was seen in all three parameters viz knowledge, attitude and practices. Conclusion: Continuing Educational interventions should be started at all level which highlights the importance of screening and prevention of cancer in women. Key-wordsCervical Cancer, Women, Perception Barriers, Effectiveness INTRODUCTION Cancer is leading cause of mortality among adults with new cases are increasing all over the world. It is expected by 2020 the world population will increase to 7.5 billion; of this, approximately 15 million new cancer cases will be diagnosed and 12 million cancer patients will die. [1] Women of all races and ethnicities are at risk of cervical cancer. In India yearly around 0.95 million new cases are detected with 0.63 million deaths. cervical cancer accounts for 8.5% deaths yearly and most of which occur in developing countries. Cervical cancer is the single largest killer of middle-aged women in India. Access this article online Quick Response Code Website: www.ijlssr.com DOI: 10.21276/ijlssr.2017.3.6.15 India bears about one fifth of the world’s burden of cervical cancer. [2-3] Although fatality is high but cancers are largely preventable by effective screening programmes. [4] Papanicolaou smears (Pap test) provide a simple, basic and inexpensive technique for detection of early cancerous and precancerous lesion in otherwise asymptomatic women. [18] Decision to participate in such cancer screening programs depends upon the knowledge, beliefs and attitudes about the disease and the screening tests. A study done in Kolkata among female students reflected low level of knowledge of cervical cancer and its risk factors and only 11% and 15% were aware of Pap smear and HPV respecti
背景:所有种族和民族的妇女都有患宫颈癌的危险。在印度,每年发现约95万新病例,高负担为63万。印度承担着世界上约五分之一的宫颈癌负担。虽然死亡率很高,但通过有效的筛查规划,癌症在很大程度上是可以预防的。设计:本准实验研究以2013年2月至2013年9月在学位院校就读的女学生为研究对象。干预:教育干预是通过参与式学习的方式进行的,包括使用幻灯片,粉笔和谈话的讲座以及问答法。采用预先设计的问卷调查和焦点小组讨论两种方式收集数据。数据分析:使用Epi Info 2000输入和分析数据。使用Atlas ti软件对定性信息进行分析。采用配对t检验测量干预效果。结果:共有149名学生参与研究并成功随访。参与者的平均年龄为18.5岁。在149名参与者中,4.1%有癌症家族史。研究发现,18.8%的人从未听说过癌症。在干预后的测试中,在知识、态度和实践这三个参数上都有显著的改善。结论:应在各级开展继续教育干预,强调妇女癌症筛查和预防的重要性。宫颈癌,妇女,认知障碍,疗效介绍癌症是成人死亡的主要原因,世界各地的新发病例不断增加。预计到2020年世界人口将增加到75亿;其中,大约1500万新的癌症病例将被诊断出来,1200万癌症患者将死亡。[1]所有种族和民族的妇女都有患宫颈癌的风险。在印度,每年约有95万新病例被发现,63万人死亡。宫颈癌每年占死亡人数的8.5%,其中大多数发生在发展中国家。子宫颈癌是印度中年妇女的最大杀手。快速响应代码网站:www.ijlssr.com DOI: 10.21276/ijlssr.2017.3.6.15印度承担着世界上约五分之一的宫颈癌负担。[2-3]虽然死亡率很高,但通过有效的筛查规划,癌症在很大程度上是可以预防的。[4]巴氏涂片(巴氏试验)为无症状妇女提供了一种简单、基本和廉价的早期癌症和癌前病变检测技术。[18]参加这种癌症筛查项目的决定取决于对疾病和筛查试验的知识、信念和态度。在加尔各答对女学生进行的一项研究表明,女学生对宫颈癌及其危险因素的认识水平较低,分别只有11%和15%的人知道子宫颈抹片检查和HPV。[4]此外,即使在可以免费进行检查的地方,许多妇女仍未接受检查。[5]不幸的是,在像印度这样的发展中国家,人们缺乏对风险因素的认识,也缺乏通过筛查和治疗早期发现癌前病变的意识。研究论文;j .生活。科学。Scienti。研究报告,3(6):1516-1521 nov 2017版权所有©2015-2017| IJLSSR by CC by - nc 4.0国际许可页面1517有充分的证据表明,宗教和文化差异影响了人们对健康预防的看法,可能会减少筛查实践的发生率。[6] Jayant等[7]和Saha等[8]建议提高意识,促使有症状的个体在早期寻求医疗咨询和治疗,从而提高生存率。材料与方法研究设计本准实验研究在学位学院(工程,理工学院,梅尔马鲁瓦图和艺术与商业学院,印度坎奇普兰区,Vandhawasi)的女学生中进行,该学院位于社区医学系和梅尔马鲁瓦图医学科学与研究所的现场实践区及其周围。研究时间为2013年2月1日至2013年9月30日。在教育干预前后分别进行两次数据收集。同时进行教育干预。并在干预后至少30天收集测试后数据。Saha等人[8]记录了攻读学位学院的女学生中11%的意识水平。在95%置信区间的基础上,意识的流行率为11%,绝对误差为5%,总样本量为144。考虑到无应答率高达10%,最终样本量为158。但是我们无法跟踪所有的学生,直到后期测试,经过彻底的验证,研究者可以分析149名学生的数据。
{"title":"An Assessment of Awareness, Barriers in Perception of Cervical Cancer and Effect Estimation of Educational Intervention Programme in Females","authors":"Ashwini G. Darokar, R. Patil, Amol Patel, M. Nivetha","doi":"10.21276/IJLSSR.2017.3.6.15","DOIUrl":"https://doi.org/10.21276/IJLSSR.2017.3.6.15","url":null,"abstract":"Background: Women of all races and ethnicities are at risk of cervical cancer. India, around 0.95 million new cases are detected yearly with high burden of 0.63 million. India bears about one fifth of the world’s burden of cervical cancer. Although fatality is high but cancers are largely preventable by effective screening programmes. Design: The present quasi-experimental study was conducted among female students studying in degree colleges from Feb. 2013 to Sept. 2013. Intervention: Educational intervention was conducted through sessions of participatory learning approach which included lectures using power-point, chalk and talk and question-answers method. Data was collected twice by administering predesigned questionnaire and conducting focus group discussion. Data Analysis: Data entered and analyzed using Epi Info 2000. To analyze qualitative information Atlas ti software was used. Paired t-test was used to measure the effect of intervention. Results: Total 149 students were the part of the study and successfully followed. Mean age of the participant was 18.5 years. Out of the 149 participants 4.1% had family history of the cancer. In the study it was observed that 18.8% had not ever heard about the cancer. In the post intervention test significant improvement was seen in all three parameters viz knowledge, attitude and practices. Conclusion: Continuing Educational interventions should be started at all level which highlights the importance of screening and prevention of cancer in women. Key-wordsCervical Cancer, Women, Perception Barriers, Effectiveness INTRODUCTION Cancer is leading cause of mortality among adults with new cases are increasing all over the world. It is expected by 2020 the world population will increase to 7.5 billion; of this, approximately 15 million new cancer cases will be diagnosed and 12 million cancer patients will die. [1] Women of all races and ethnicities are at risk of cervical cancer. In India yearly around 0.95 million new cases are detected with 0.63 million deaths. cervical cancer accounts for 8.5% deaths yearly and most of which occur in developing countries. Cervical cancer is the single largest killer of middle-aged women in India. Access this article online Quick Response Code Website: www.ijlssr.com DOI: 10.21276/ijlssr.2017.3.6.15 India bears about one fifth of the world’s burden of cervical cancer. [2-3] Although fatality is high but cancers are largely preventable by effective screening programmes. [4] Papanicolaou smears (Pap test) provide a simple, basic and inexpensive technique for detection of early cancerous and precancerous lesion in otherwise asymptomatic women. [18] Decision to participate in such cancer screening programs depends upon the knowledge, beliefs and attitudes about the disease and the screening tests. A study done in Kolkata among female students reflected low level of knowledge of cervical cancer and its risk factors and only 11% and 15% were aware of Pap smear and HPV respecti","PeriodicalId":22509,"journal":{"name":"The International Journal of Life-Sciences Scientific Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90668600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Significance of Thrombocytosis in Epithelial Ovarian Tumors 卵巢上皮性肿瘤血小板增多的意义
Pub Date : 2017-11-01 DOI: 10.21276/IJLSSR.2017.3.6.7
S. Ramu, R. Sinha
Thrombocytosis has been reported in association with ovarian tumors and is often a poor prognostic factor. The present study aims to study the incidence of pre-operative thrombocytosis in epithelial ovarian tumors and to correlate it with anemia, serum CA-125 levels, presence or ascites, FIGO staging and tumor histology. Total 160 cases of resected specimens of surface epithelial ovarian tumors (SEOT) received in department of Pathology, Kasturba Medical College Mangalore were studied. The preoperative platelet count, haemoglobin levels and serum CA-125 levels were collected. The presence and degree of ascites was assessed. International Federation of Obstetrics and Gynaecology (FIGO) staging was done. The incidence of thrombocytosis and its correlation with the presence of anaemia, elevated CA-125 levels, FIGO stage and presence and degree of ascites among malignant cases were statistically analysed. The incidence of pre-operative thrombocytosis was noted more in malignant SEOTs 80% (40/160). The mean pre-operative platelet count in the present study was 321X10 9 /L. It was more prevalent in serous epithelial ovarian tumors (83.3%) and these findings were statistically significant (p=0.0001). There was a statistically significant association of pre-operative thrombocytosis with the presence and degree of ascites and advanced FIGO staging (p=0.0001). Pre-operative thrombocytosis is a frequent finding in malignant SEOTs and is associated with other prognostic markers. This implies that thrombocytosis is probably a marker of tumor aggressiveness, and that platelet may have a role in cancer growth and progression. Thus, presence of pre-operative thrombocytosis has significance as a poor prognosticator in epithelial ovarian tumors. Key-wordsThrombocytosis, Surface Epithelial Ovarian Tumors (SEOT), CA 125, FIGO staging INTRODUCTION Thrombocytosis refers to platelet count above the normal value (>400x10 9 /L). Thrombocytosis can be primary or secondary. Malignancy is one of the most important causes of secondary thrombocytosis. [1-2] The association between thrombocytosis and malignancies is known. [3] Thrombocytosis has been reported in variety of neoplastic diseases including Hodgkin lymphoma, sarcoma and several solid tumors such as lung, renal, gastric, breast, pancreatic, colonic, and gynecological malignancies. [4-8] In ovarian cancer thrombocytosis is a poor prognostic factor in locally advanced disease. [9-10] Chalas et al. [11] found thrombocytosis in 56% of the reviewed cases of epithelial ovarian malignancies. The etiology of neoplastic megakaryopoiesis remains unclear, it might be related to increased platelet production are due to certain cytokines (IL-6, IL-1) and growth factors released by malignant cells. [7] Access this article online Quick Response Code Website:
据报道,血小板增多症与卵巢肿瘤有关,通常是一个预后不良的因素。本研究旨在研究卵巢上皮性肿瘤术前血小板增多的发生率,并探讨其与贫血、血清CA-125水平、是否存在腹水、FIGO分期和肿瘤组织学的关系。本文对在曼格洛尔卡斯图尔巴医学院病理科收到的160例卵巢表面上皮性肿瘤(SEOT)切除标本进行了研究。收集术前血小板计数、血红蛋白水平和血清CA-125水平。评估腹水的存在和程度。进行国际妇产科联合会(FIGO)分期。统计分析恶性病例中血小板增多的发生率及其与贫血、CA-125水平升高、FIGO分期、腹水存在及程度的相关性。术前血小板增多在恶性seot中发生率更高,为80%(40/160)。本研究术前平均血小板计数为321x109 /L。在卵巢浆液上皮性肿瘤中更为普遍(83.3%),这些发现具有统计学意义(p=0.0001)。术前血小板增多与腹水的存在、程度和晚期FIGO分期有统计学意义(p=0.0001)。术前血小板增多是恶性SEOTs的常见发现,并与其他预后标志物相关。这表明血小板增多可能是肿瘤侵袭性的标志,血小板可能在癌症的生长和进展中起作用。因此,术前血小板增多作为卵巢上皮性肿瘤的不良预后因素具有重要意义。关键词血小板增多,卵巢表面上皮性肿瘤(SEOT), ca125, FIGO分期介绍血小板增多是指血小板计数高于正常值(>400x10 9 /L)。血小板增多症可为原发性或继发性。恶性肿瘤是继发性血小板增多症的最重要原因之一。[1-2]血小板增多症与恶性肿瘤之间的关系是已知的。[3]血小板增多症在多种肿瘤疾病中有报道,包括霍奇金淋巴瘤、肉瘤和几种实体肿瘤,如肺、肾、胃、乳腺、胰腺、结肠和妇科恶性肿瘤。[4-8]在卵巢癌中,血小板增多是局部晚期疾病的不良预后因素。[9-10] Chalas等[11]发现56%的卵巢上皮性恶性肿瘤患者有血小板增多。肿瘤巨核生成的病因尚不清楚,可能与恶性细胞释放的某些细胞因子(IL-6、IL-1)和生长因子导致血小板生成增加有关。[7]访问本文的在线快速响应代码网站:
{"title":"Significance of Thrombocytosis in Epithelial Ovarian Tumors","authors":"S. Ramu, R. Sinha","doi":"10.21276/IJLSSR.2017.3.6.7","DOIUrl":"https://doi.org/10.21276/IJLSSR.2017.3.6.7","url":null,"abstract":"Thrombocytosis has been reported in association with ovarian tumors and is often a poor prognostic factor. The present study aims to study the incidence of pre-operative thrombocytosis in epithelial ovarian tumors and to correlate it with anemia, serum CA-125 levels, presence or ascites, FIGO staging and tumor histology. Total 160 cases of resected specimens of surface epithelial ovarian tumors (SEOT) received in department of Pathology, Kasturba Medical College Mangalore were studied. The preoperative platelet count, haemoglobin levels and serum CA-125 levels were collected. The presence and degree of ascites was assessed. International Federation of Obstetrics and Gynaecology (FIGO) staging was done. The incidence of thrombocytosis and its correlation with the presence of anaemia, elevated CA-125 levels, FIGO stage and presence and degree of ascites among malignant cases were statistically analysed. The incidence of pre-operative thrombocytosis was noted more in malignant SEOTs 80% (40/160). The mean pre-operative platelet count in the present study was 321X10 9 /L. It was more prevalent in serous epithelial ovarian tumors (83.3%) and these findings were statistically significant (p=0.0001). There was a statistically significant association of pre-operative thrombocytosis with the presence and degree of ascites and advanced FIGO staging (p=0.0001). Pre-operative thrombocytosis is a frequent finding in malignant SEOTs and is associated with other prognostic markers. This implies that thrombocytosis is probably a marker of tumor aggressiveness, and that platelet may have a role in cancer growth and progression. Thus, presence of pre-operative thrombocytosis has significance as a poor prognosticator in epithelial ovarian tumors. Key-wordsThrombocytosis, Surface Epithelial Ovarian Tumors (SEOT), CA 125, FIGO staging INTRODUCTION Thrombocytosis refers to platelet count above the normal value (>400x10 9 /L). Thrombocytosis can be primary or secondary. Malignancy is one of the most important causes of secondary thrombocytosis. [1-2] The association between thrombocytosis and malignancies is known. [3] Thrombocytosis has been reported in variety of neoplastic diseases including Hodgkin lymphoma, sarcoma and several solid tumors such as lung, renal, gastric, breast, pancreatic, colonic, and gynecological malignancies. [4-8] In ovarian cancer thrombocytosis is a poor prognostic factor in locally advanced disease. [9-10] Chalas et al. [11] found thrombocytosis in 56% of the reviewed cases of epithelial ovarian malignancies. The etiology of neoplastic megakaryopoiesis remains unclear, it might be related to increased platelet production are due to certain cytokines (IL-6, IL-1) and growth factors released by malignant cells. [7] Access this article online Quick Response Code Website:","PeriodicalId":22509,"journal":{"name":"The International Journal of Life-Sciences Scientific Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75322571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment for Variation of Air Pollution Tolerance Index of Selected Plants in Bengaluru Urban 班加罗尔市区选定植物耐空气污染指数变化评价
Pub Date : 2017-11-01 DOI: 10.21276/IJLSSR.2017.3.6.16
Manjunath B.T, Jayarama Reddy
To develop the usefulness of Caesalpinia pulcherrima and Catharanthus roseus plants as bioindicators, which entail an utmost importance for a particular situation. This study focuses on the assessment of air pollution tolerance index (APTI) of two selected plant species commonly found along roadsides in Bengaluru, India. The plant species selected for the study were Caesalpinia pulcherrima and Catharanthus roseus. The plants were evaluated in terms of APTI by analyzing four different biochemical parameters: Leaf relative water content (RWC), Ascorbic acid content (AA), Total leaf chlorophyll (TCh), and pH of leaf extract. Based on APTI Caesalpinia pulcherrima was found to be more tolerant compared to Catharanthus roseus. Species with lower APTI value are considered sensitive species, which can be used as a biological indicator for further monitoring of air quality. Species with higher APTI value are tolerant species and thus, can be planted for pollution abatement in order to control and reduce environmental pollution. Key-wordsAir pollution tolerance index (APTI), biochemical parameters, roadside plants, Biomonitors INTRODUCTION Air Pollution can be simply defined as an undesirable change in the physical, chemical and biological properties of air due to anthropogenic or any other cause. An air pollutant is a substance in the air that can have adverse effects on humans and the ecosystem. The substance can be solid particles, liquid droplets, or gases. Air pollution is a serious problem throughout the world. Rapid industrialization and vehicular traffic especially in the urban areas of India lead to the deterioration of air quality by adding toxic gases and other substances to the atmosphere. All combustion releases gases and particulate matter into the air, which includes SO2, NO2, CO and soot particles as well as smaller quantities of toxic metals, organic molecules, and radioactive isotopes etc. The degradation of air quality is the major environmental problem that affects many urban and industrial sites and the surrounding regions worldwide. Although various efforts have been done for environmental restoration in India still it seems to be a formidable task. A pollutant can be of natural origin or manmade. Air Pollution results in huge harm to the living organisms. Access this article online Quick Response Code Website:
为了开发具有特殊情况下重要意义的花楸属植物和花楸属植物作为生物指示物的应用价值。本研究的重点是评估两种常见于印度班加罗尔路边的植物的空气污染耐受指数(APTI)。本研究选择的植物种为细叶花和玫瑰花。通过分析叶片相对含水量(RWC)、抗坏血酸含量(AA)、叶片总叶绿素含量(TCh)和叶片提取物pH等4个不同的生化参数,对植物的APTI进行评价。基于APTI分析发现,与玫瑰花(Catharanthus roseus)相比,该花的耐受性更强。APTI值较低的物种被认为是敏感物种,可以作为进一步监测空气质量的生物指标。APTI值较高的品种为耐受性强的品种,可用于污染治理,以控制和减少环境污染。关键词空气污染耐受指数(APTI),生化参数,路边植物,生物监测仪介绍空气污染可以简单地定义为由于人为或任何其他原因导致的空气的物理、化学和生物特性的不良变化。空气污染物是空气中对人类和生态系统有不利影响的物质。这种物质可以是固体颗粒、液滴或气体。空气污染在全世界都是一个严重的问题。快速的工业化和车辆交通,特别是在印度的城市地区,通过向大气中添加有毒气体和其他物质,导致空气质量恶化。所有的燃烧都会向空气中释放气体和颗粒物质,其中包括SO2、NO2、CO和煤烟颗粒,以及少量的有毒金属、有机分子和放射性同位素等。空气质量的恶化是影响世界各地许多城市和工业场所及其周边地区的主要环境问题。尽管印度为环境恢复做了各种努力,但这似乎是一项艰巨的任务。污染物可以是天然的,也可以是人为的。空气污染对生物造成了巨大的危害。在线阅读本文快速响应代码网站:
{"title":"Assessment for Variation of Air Pollution Tolerance Index of Selected Plants in Bengaluru Urban","authors":"Manjunath B.T, Jayarama Reddy","doi":"10.21276/IJLSSR.2017.3.6.16","DOIUrl":"https://doi.org/10.21276/IJLSSR.2017.3.6.16","url":null,"abstract":"To develop the usefulness of Caesalpinia pulcherrima and Catharanthus roseus plants as bioindicators, which entail an utmost importance for a particular situation. This study focuses on the assessment of air pollution tolerance index (APTI) of two selected plant species commonly found along roadsides in Bengaluru, India. The plant species selected for the study were Caesalpinia pulcherrima and Catharanthus roseus. The plants were evaluated in terms of APTI by analyzing four different biochemical parameters: Leaf relative water content (RWC), Ascorbic acid content (AA), Total leaf chlorophyll (TCh), and pH of leaf extract. Based on APTI Caesalpinia pulcherrima was found to be more tolerant compared to Catharanthus roseus. Species with lower APTI value are considered sensitive species, which can be used as a biological indicator for further monitoring of air quality. Species with higher APTI value are tolerant species and thus, can be planted for pollution abatement in order to control and reduce environmental pollution. Key-wordsAir pollution tolerance index (APTI), biochemical parameters, roadside plants, Biomonitors INTRODUCTION Air Pollution can be simply defined as an undesirable change in the physical, chemical and biological properties of air due to anthropogenic or any other cause. An air pollutant is a substance in the air that can have adverse effects on humans and the ecosystem. The substance can be solid particles, liquid droplets, or gases. Air pollution is a serious problem throughout the world. Rapid industrialization and vehicular traffic especially in the urban areas of India lead to the deterioration of air quality by adding toxic gases and other substances to the atmosphere. All combustion releases gases and particulate matter into the air, which includes SO2, NO2, CO and soot particles as well as smaller quantities of toxic metals, organic molecules, and radioactive isotopes etc. The degradation of air quality is the major environmental problem that affects many urban and industrial sites and the surrounding regions worldwide. Although various efforts have been done for environmental restoration in India still it seems to be a formidable task. A pollutant can be of natural origin or manmade. Air Pollution results in huge harm to the living organisms. Access this article online Quick Response Code Website:","PeriodicalId":22509,"journal":{"name":"The International Journal of Life-Sciences Scientific Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75402798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Study of Phytochemical Analysis and Antioxidant Activity of Allium sativum of Bundelkhand Region 本德尔坎德地区葱属植物化学分析及抗氧化活性研究
Pub Date : 2017-11-01 DOI: 10.21276/IJLSSR.2017.3.6.4
Vandana Singh, Ramesh Kumar
{"title":"Study of Phytochemical Analysis and Antioxidant Activity of Allium sativum of Bundelkhand Region","authors":"Vandana Singh, Ramesh Kumar","doi":"10.21276/IJLSSR.2017.3.6.4","DOIUrl":"https://doi.org/10.21276/IJLSSR.2017.3.6.4","url":null,"abstract":"","PeriodicalId":22509,"journal":{"name":"The International Journal of Life-Sciences Scientific Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75415565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 38
期刊
The International Journal of Life-Sciences Scientific Research
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1