Objective: Efficiency of traditional and algorithmic diagnostics comparison; Differential Diagnostic Algorithm creation for effective X-ray differential diagnostics of diseases accompanied with local opacity. Methods: Comparative evaluation of X-ray traditional and algorithmic diagnostics has been performed by principle of other equal conditions. The first stage of independent diagnostics has reflected the results of traditional medical education. The same radiograms have been used by the same examinees in the same time for repeated diagnostics with original innovative diagnostic algorithm on the second stage.Results: X-ray diagnostic algorithm significantly decreased of errors obtained at independent diagnostics. Conclusion: Traditional X-ray diagnostics based on nosological thinking is ineffective. Syndromic algorithmic X-ray diagnostics used innovative the most effective intellectual activity, therefore, optimized results radically.Definition: Differential Diagnostic Algorithm or diagnostic algorithm is the exact comprehensible to all determination about step-by-step of elementary intellectual operations and actions in the certain sequence for establishment of a diagnosis of each of all diseases manifested by the given leading
{"title":"Problems Of Diseases Manifested By X-ray Local Opacity Syndrome, And Differential Diagnostic Algorithm For Its Solution","authors":"L. B. Naumov","doi":"10.5580/1af5","DOIUrl":"https://doi.org/10.5580/1af5","url":null,"abstract":"Objective: Efficiency of traditional and algorithmic diagnostics comparison; Differential Diagnostic Algorithm creation for effective X-ray differential diagnostics of diseases accompanied with local opacity. Methods: Comparative evaluation of X-ray traditional and algorithmic diagnostics has been performed by principle of other equal conditions. The first stage of independent diagnostics has reflected the results of traditional medical education. The same radiograms have been used by the same examinees in the same time for repeated diagnostics with original innovative diagnostic algorithm on the second stage.Results: X-ray diagnostic algorithm significantly decreased of errors obtained at independent diagnostics. Conclusion: Traditional X-ray diagnostics based on nosological thinking is ineffective. Syndromic algorithmic X-ray diagnostics used innovative the most effective intellectual activity, therefore, optimized results radically.Definition: Differential Diagnostic Algorithm or diagnostic algorithm is the exact comprehensible to all determination about step-by-step of elementary intellectual operations and actions in the certain sequence for establishment of a diagnosis of each of all diseases manifested by the given leading","PeriodicalId":22526,"journal":{"name":"The Internet Journal of Radiology","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82046199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neurofibromatosis type 2(NF-2) is an often devastating autosomal dominant disorder which, until relatively recently, was confused with its more common namesake neurofibromatosis type 1. NF2 is a distinct disease which must be separated clinically & radiologically from neurofibromatosis1. Subjects who inherit a mutated allele of the NF2 gene inevitably develop schwannomas, affecting particularly the superior vestibular branch of the 8th cranial nerve, usually bilaterally. Meningiomas and other benign central nervous system tumours such as ependymomas are other common features. Much of the morbidity from these tumours results from their treatment. As a classical tumour suppressor, inactivation of the NF2 gene product, merlin/schwannomin, leads to the development of both NF2 associated and sporadic tumours. Merlin/schwannomin associates with proteins at the cell cytoskeleton near the plasma membrane and it inhibits cell proliferation, adhesion, and migration.
{"title":"Cranial and Spinal involvement in Neurofibromatosis type 2","authors":"S. Aneja, Rishu Sangal, M. Murthy, S. Sethi","doi":"10.5580/1b85","DOIUrl":"https://doi.org/10.5580/1b85","url":null,"abstract":"Neurofibromatosis type 2(NF-2) is an often devastating autosomal dominant disorder which, until relatively recently, was confused with its more common namesake neurofibromatosis type 1. NF2 is a distinct disease which must be separated clinically & radiologically from neurofibromatosis1. Subjects who inherit a mutated allele of the NF2 gene inevitably develop schwannomas, affecting particularly the superior vestibular branch of the 8th cranial nerve, usually bilaterally. Meningiomas and other benign central nervous system tumours such as ependymomas are other common features. Much of the morbidity from these tumours results from their treatment. As a classical tumour suppressor, inactivation of the NF2 gene product, merlin/schwannomin, leads to the development of both NF2 associated and sporadic tumours. Merlin/schwannomin associates with proteins at the cell cytoskeleton near the plasma membrane and it inhibits cell proliferation, adhesion, and migration.","PeriodicalId":22526,"journal":{"name":"The Internet Journal of Radiology","volume":"24 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91493677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Variants of the bicipitolabral complex in MR imaging of the shoulder are important to recognise due to their close simulation of labral tears. Three types of the same are described.
{"title":"Normal variants of the bicipitolabral complex in MRI of the shoulder","authors":"P. Chatterjee, J. Sureka","doi":"10.5580/2911","DOIUrl":"https://doi.org/10.5580/2911","url":null,"abstract":"Variants of the bicipitolabral complex in MR imaging of the shoulder are important to recognise due to their close simulation of labral tears. Three types of the same are described.","PeriodicalId":22526,"journal":{"name":"The Internet Journal of Radiology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75917220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Retroperitoneal bronchogenic cyst containing intracystic milk of calcium is extremely rare and only one case of retroperitoneal bronchogenic cyst with a small amount of milk of calcium has ever been reported. We report a case of periadrenal retroperitoneal bronchogenic cyst with intracystic milk of calciumn and its serial change into the nodular cyst wall calcifications over the course of two year. The patient was treated with laparoscopic resection of retroperitoneal bronchogenic cyst.
{"title":"Periadrenal Bronchogenic Cyst with Intracystic Milk of Calcium","authors":"Soo-Youn Park, S. Hwang","doi":"10.5580/1268","DOIUrl":"https://doi.org/10.5580/1268","url":null,"abstract":"Retroperitoneal bronchogenic cyst containing intracystic milk of calcium is extremely rare and only one case of retroperitoneal bronchogenic cyst with a small amount of milk of calcium has ever been reported. We report a case of periadrenal retroperitoneal bronchogenic cyst with intracystic milk of calciumn and its serial change into the nodular cyst wall calcifications over the course of two year. The patient was treated with laparoscopic resection of retroperitoneal bronchogenic cyst.","PeriodicalId":22526,"journal":{"name":"The Internet Journal of Radiology","volume":"96 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87482818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Rinaldi, T. Bartalena, G. Giannelli, L. Braccaioli
A case of Swyer-James syndrome is described with emphasis on multidetector CT (MDCT) findings and the diagnostic value of post-processing techniques. CASE REPORT A 53-year-old woman was referred to our radiology department for the onset of exertional dyspnea since 3 months. Chest X-rays showed reduced left lung volume with diminished vascular markings and hyperinflation of the right lung which was see herniating beyond the midline (Fig.1a) Contrast enhanced MDCT of the thorax was performed on a 16-slice scanner. Review of the axial images and of the multiplanar post-processed reconstructions (Fig. 1b,c) confirmed lung asymmetry and showed increased lucency of the left lung relative to the right. Left bronchial tree was patent with diffuse peripheral bronchiectasis. Left-sided pulmonary arteries were present but showed significantly decreased caliber (Fig. 1d). Radiologic findings were consistent with Swyer-James syndrome (SJS). DISCUSSION SJS is believed to represent the result of postinfectious bronchiolitis obliterans in infancy or early childhood that damages the terminal and respiratory bronchioles preventing the normal development of alveolar buds. [1] This lead to reduced lung volumes in adulthood and air-trapping. Patients may be asymptomatic or may experience cough, chronic pulmonary infections, decreased exercise tolerance, and hemoptysis. Chest x-ray findings consist of a unilateral small lung with hyperlucency and air trapping. CT aids in the differential diagnosis between SJS, bronchial obstruction and congenital vascular anomalies like unilateral pulmonary artery agenesis or scimitar syndrome, showing preserved anatomy of tracheobronchial tree and pulmonary arteries. [23] Currently available post-processing tools improve MDCT diagnostic performances; in particular the combination of multiplanar reformatted images with maximum intensity projection (MIP) is most effective in vascular imaging while minimum intensity projection (minIP) reconstructions help to disclose differences in lung attenuation and depiction of bronchial structures. [4] Figure 1 Figure 1 a. Chest X-rays showing reduced left lung volume and herniation of hyperinflated right lung (arrow) b, c. Axial CT scan and minIP coronal reconstruction reveal hyperlucency of left lung and airways patency. d. Left pulmonary arteries have strikingly decreased caliber on contrast enhanced MIP coronal reconstruction CORRESPONDENCE TO Dr. Tommaso Bartalena. Radiologia III – Pol. S.OrsolaSwyer-James Syndrome: X-ray and MDCT findings 2 of 3 Malpighi, Bologna, Italy. Via Massarenti 9, Bologna, Italy. Phone: +390516363384 Fax: +39051349797 E-mail: t.bartalena@email.it References 1. Swyer PR, James GCW. A case of unilateral pulmonary emphysema. Thorax 1953;8:133-136. 2. Marti-Bonmati L, Ruiz Perales F, Catala F, Mata JM, Calonge E. CT Findings in Swyer-James Syndrome. Radiology 1989;172:477-480. 3. Moore ADA, Godwin JD, Dietrich PA, Verschakelen JA, Henderson WR Jr. Swyer-James Syndrome: CT
{"title":"Swyer-James Syndrome: X-ray and MDCT findings","authors":"M. Rinaldi, T. Bartalena, G. Giannelli, L. Braccaioli","doi":"10.5580/96e","DOIUrl":"https://doi.org/10.5580/96e","url":null,"abstract":"A case of Swyer-James syndrome is described with emphasis on multidetector CT (MDCT) findings and the diagnostic value of post-processing techniques. CASE REPORT A 53-year-old woman was referred to our radiology department for the onset of exertional dyspnea since 3 months. Chest X-rays showed reduced left lung volume with diminished vascular markings and hyperinflation of the right lung which was see herniating beyond the midline (Fig.1a) Contrast enhanced MDCT of the thorax was performed on a 16-slice scanner. Review of the axial images and of the multiplanar post-processed reconstructions (Fig. 1b,c) confirmed lung asymmetry and showed increased lucency of the left lung relative to the right. Left bronchial tree was patent with diffuse peripheral bronchiectasis. Left-sided pulmonary arteries were present but showed significantly decreased caliber (Fig. 1d). Radiologic findings were consistent with Swyer-James syndrome (SJS). DISCUSSION SJS is believed to represent the result of postinfectious bronchiolitis obliterans in infancy or early childhood that damages the terminal and respiratory bronchioles preventing the normal development of alveolar buds. [1] This lead to reduced lung volumes in adulthood and air-trapping. Patients may be asymptomatic or may experience cough, chronic pulmonary infections, decreased exercise tolerance, and hemoptysis. Chest x-ray findings consist of a unilateral small lung with hyperlucency and air trapping. CT aids in the differential diagnosis between SJS, bronchial obstruction and congenital vascular anomalies like unilateral pulmonary artery agenesis or scimitar syndrome, showing preserved anatomy of tracheobronchial tree and pulmonary arteries. [23] Currently available post-processing tools improve MDCT diagnostic performances; in particular the combination of multiplanar reformatted images with maximum intensity projection (MIP) is most effective in vascular imaging while minimum intensity projection (minIP) reconstructions help to disclose differences in lung attenuation and depiction of bronchial structures. [4] Figure 1 Figure 1 a. Chest X-rays showing reduced left lung volume and herniation of hyperinflated right lung (arrow) b, c. Axial CT scan and minIP coronal reconstruction reveal hyperlucency of left lung and airways patency. d. Left pulmonary arteries have strikingly decreased caliber on contrast enhanced MIP coronal reconstruction CORRESPONDENCE TO Dr. Tommaso Bartalena. Radiologia III – Pol. S.OrsolaSwyer-James Syndrome: X-ray and MDCT findings 2 of 3 Malpighi, Bologna, Italy. Via Massarenti 9, Bologna, Italy. Phone: +390516363384 Fax: +39051349797 E-mail: t.bartalena@email.it References 1. Swyer PR, James GCW. A case of unilateral pulmonary emphysema. Thorax 1953;8:133-136. 2. Marti-Bonmati L, Ruiz Perales F, Catala F, Mata JM, Calonge E. CT Findings in Swyer-James Syndrome. Radiology 1989;172:477-480. 3. Moore ADA, Godwin JD, Dietrich PA, Verschakelen JA, Henderson WR Jr. Swyer-James Syndrome: CT","PeriodicalId":22526,"journal":{"name":"The Internet Journal of Radiology","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73250498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A 46 year old man, a vegetarian, presented with acute onset of paresthesia (“pins and needles” sensation) involving both hands and feet of 15 days duration. He also complained of difficulty in walking and inability to feel the ground for the same period. There was no history of trauma, fever, vomiting, diarrhea, upper respiratory tract infection, visual disturbances, and bladder or bowel incontinence. On examination, the patient was restless and agitated but his higher mental functions were normal. There was impairment of sensation of fine touch, pin prick, joint position and vibration in both hands and feet bilaterally. All the deep tendon reflexes were exaggerated and symmetric, more so in the lower limbs; Plantars were extensor. Romberg's sign was positive. There was no evidence of motor weakness. His cranial nerves were normal. Spine was normal. Vision was normal. Other systemic examination did not reveal any abnormality.
{"title":"Subacute Combined Degeneration Of The Cord: Lateral Column Involvement Seen On Mri –An Uncommon Finding","authors":"L. Malhotra, S. Sethi, Jaya Shankar, T. Mehta","doi":"10.5580/2023","DOIUrl":"https://doi.org/10.5580/2023","url":null,"abstract":"A 46 year old man, a vegetarian, presented with acute onset of paresthesia (“pins and needles” sensation) involving both hands and feet of 15 days duration. He also complained of difficulty in walking and inability to feel the ground for the same period. There was no history of trauma, fever, vomiting, diarrhea, upper respiratory tract infection, visual disturbances, and bladder or bowel incontinence. On examination, the patient was restless and agitated but his higher mental functions were normal. There was impairment of sensation of fine touch, pin prick, joint position and vibration in both hands and feet bilaterally. All the deep tendon reflexes were exaggerated and symmetric, more so in the lower limbs; Plantars were extensor. Romberg's sign was positive. There was no evidence of motor weakness. His cranial nerves were normal. Spine was normal. Vision was normal. Other systemic examination did not reveal any abnormality.","PeriodicalId":22526,"journal":{"name":"The Internet Journal of Radiology","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85376508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Macleod syndrome is an important cause of unilateral luceny on chest radiograph and usually detected incidentally on imaging done for some other reason or sometimes with respiratory problems including infections or hemoptysis. We present a case of Macleod syndrome in an adult who presented with hemoptysis due to associated bronchiectatsis.
{"title":"Macleod syndrome presenting as hemoptysis","authors":"M. Singhal, R. Mathur, G. P. Vashist, V. Nangia","doi":"10.5580/726","DOIUrl":"https://doi.org/10.5580/726","url":null,"abstract":"Macleod syndrome is an important cause of unilateral luceny on chest radiograph and usually detected incidentally on imaging done for some other reason or sometimes with respiratory problems including infections or hemoptysis. We present a case of Macleod syndrome in an adult who presented with hemoptysis due to associated bronchiectatsis.","PeriodicalId":22526,"journal":{"name":"The Internet Journal of Radiology","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80146978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Khandanpour, S. Girling, P. Wilson, F. Meyer, M. Armon, J. Cockburn
OBJECTIVES To review standards of angiography and angioplasty in the light of a study of post-intervention complications. METHODSData for early (24-hours) and 30-day complications after diagnostic angiography (DA) and percutaneous transluminal angioplasty (PTA) were prospectively examined over a 28-month period. Complication rates were compared with the published standards. RESULTS758 patients were included. Major complications occurred in 1.18%. The commonest complication was haematoma (n=16, 2.11%), of which two were major. Systemic problems (nausea, vomiting, vasovagal syncope, transient hypotension and transient arrhythmias) accounted for 1.45%. Arterial occlusion, minor vessel rupture, distal emboli and renal failure constituted the remainder with an incidence of 0.66%. No pseudoaneurysms or arteriovenous fistulae occurred. The 30day mortality rate was 1.82%.CONCLUSIONThis study demonstrated lower mortality and morbidity than published standards in 2001. Standards of DA developed by the Society of Cardiovascular and Interventional Radiology (2001SCVIR) could be extended to include PTA. Pseudoaneurysm appears to be avoidable.
{"title":"Standards of angiography & percutaneous transluminal angioplasty and their application to current practice","authors":"N. Khandanpour, S. Girling, P. Wilson, F. Meyer, M. Armon, J. Cockburn","doi":"10.5580/6fd","DOIUrl":"https://doi.org/10.5580/6fd","url":null,"abstract":"OBJECTIVES To review standards of angiography and angioplasty in the light of a study of post-intervention complications. METHODSData for early (24-hours) and 30-day complications after diagnostic angiography (DA) and percutaneous transluminal angioplasty (PTA) were prospectively examined over a 28-month period. Complication rates were compared with the published standards. RESULTS758 patients were included. Major complications occurred in 1.18%. The commonest complication was haematoma (n=16, 2.11%), of which two were major. Systemic problems (nausea, vomiting, vasovagal syncope, transient hypotension and transient arrhythmias) accounted for 1.45%. Arterial occlusion, minor vessel rupture, distal emboli and renal failure constituted the remainder with an incidence of 0.66%. No pseudoaneurysms or arteriovenous fistulae occurred. The 30day mortality rate was 1.82%.CONCLUSIONThis study demonstrated lower mortality and morbidity than published standards in 2001. Standards of DA developed by the Society of Cardiovascular and Interventional Radiology (2001SCVIR) could be extended to include PTA. Pseudoaneurysm appears to be avoidable.","PeriodicalId":22526,"journal":{"name":"The Internet Journal of Radiology","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90890290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Osteonecrosis is a common complication of chronic or repetitive steroid treatment.A 55 year-old black man with a history of ulcerative colitis for 30 years, treated with multiple courses of steroids is presented in this clinical vignette. Multifocal extensive osteonecrosis was detected on imaging studies.
{"title":"Steroid-induced Extensive Bilateral Femoral and Tibial Bone Infarcts in a Patient with Ulcerative Colitis","authors":"I. Chernev, K. Yan","doi":"10.5580/4a6","DOIUrl":"https://doi.org/10.5580/4a6","url":null,"abstract":"Osteonecrosis is a common complication of chronic or repetitive steroid treatment.A 55 year-old black man with a history of ulcerative colitis for 30 years, treated with multiple courses of steroids is presented in this clinical vignette. Multifocal extensive osteonecrosis was detected on imaging studies.","PeriodicalId":22526,"journal":{"name":"The Internet Journal of Radiology","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89542531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vitamin B12 deficiency may be the consequence of several pathological conditions . The most frequent neurological manifestation is the subacute combined degeneration (SCD) of the spinal cord and polyneuropathy, rarely dementia and damage of the optic nerve occur. Numbness of the limbs and trunk is an early symptom; weakness, clumsiness and spasticity, abnormal reflexes, gait ataxia develop later. MRI reveals hyperintensities involving dorsal columns of spinal cord in cervical and upper dorsal region. Timely parenteral Vit B12 can result in complete resolution clinically as well as radiologically.
{"title":"Subacute Combined Degeneration Of The Cord","authors":"G. Chand, Vg Maller","doi":"10.5580/2ec","DOIUrl":"https://doi.org/10.5580/2ec","url":null,"abstract":"Vitamin B12 deficiency may be the consequence of several pathological conditions . The most frequent neurological manifestation is the subacute combined degeneration (SCD) of the spinal cord and polyneuropathy, rarely dementia and damage of the optic nerve occur. Numbness of the limbs and trunk is an early symptom; weakness, clumsiness and spasticity, abnormal reflexes, gait ataxia develop later. MRI reveals hyperintensities involving dorsal columns of spinal cord in cervical and upper dorsal region. Timely parenteral Vit B12 can result in complete resolution clinically as well as radiologically.","PeriodicalId":22526,"journal":{"name":"The Internet Journal of Radiology","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2008-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76073220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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