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Direct Anterior Approach: Risk Factor for Early Femoral Failure of Cementless Total Hip Arthroplasty A Multicenter Study 直接前路入路:无水泥全髋关节置换术早期股骨衰竭的危险因素:一项多中心研究
Pub Date : 2017-01-18 DOI: 10.2106/JBJS.16.00060
R. Meneghini, A. S. Elston, Antonia F. Chen, M. Kheir, T. Fehring, B. Springer
Background: The direct anterior approach for total hip arthroplasty (THA) is marketed with claims of superiority over other approaches. Femoral exposure can be technically challenging and potentially lead to early failure. We examined whether surgical approach is associated with early THA failure. Methods: A retrospective review of 478 consecutive early revision THAs performed within 5 years after the primary THAs at 3 academic centers from 2011 through 2014 was carried out. Exclusion criteria resulted in a final analysis sample of 342 early-failure THAs. The surgical approach of the primary operation that was revised, the time to the revision, and the etiology of the failure leading to the revision were documented. Results: Analysis of the revisions due to early femoral failure showed them to be more common in patients who had undergone the direct anterior approach (57/112; 50.9%) than in those treated with the direct lateral (39/112; 34.8%) or the posterior (16/112; 14.3%) approach (p = 0.001). In multivariate regression analysis controlling for age, sex, laterality, Dorr bone type, body mass index (BMI) at revision, bilateral procedure (yes/no), and femoral stem type, the direct anterior approach remained a significant predictor of early femoral failure (p = 0.007). The majority of early revisions due to instability were associated with the posterior (19/40; 47.5%) or direct anterior (15/40; 37.5%) approach (p = 0.001 for the comparison with the direct lateral approach [6/40; 15.0%]). Conclusions: Despite claims of earlier recovery and improved outcomes with the direct anterior approach for THA, our findings indicate that that approach may confer a greater risk of early femoral failure and, along with the posterior approach, confer a greater risk of early instability compared with the direct lateral approach. Level of Evidence: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
背景:全髋关节置换术(THA)的直接前路被认为比其他入路更优越。股骨暴露在技术上具有挑战性,并可能导致早期手术失败。我们研究了手术入路是否与早期THA失败有关。方法:回顾性分析2011年至2014年3个学术中心在首次tha术后5年内连续进行的478例早期翻修tha。排除标准产生了342例早期失效tha的最终分析样本。我们记录了原手术的手术入路、手术时间以及导致手术失败的病因。结果:早期股骨功能衰竭的翻修分析显示,在直接前路入路患者中更常见(57/112;50.9%)高于直接外侧支链治疗组(39/112;34.8%)或后侧(16/112;14.3%)方法(p = 0.001)。在多变量回归分析中,控制年龄、性别、侧位、背骨类型、翻修时体重指数(BMI)、双侧手术(是/否)和股骨干类型,直接前路手术仍然是早期股衰竭的重要预测因素(p = 0.007)。由于不稳定导致的早期翻修大多数与后路有关(19/40;47.5%)或直接前路(15/40;37.5%)入路与直接侧入路比较(p = 0.001) [6/40;15.0%)。结论:尽管声称THA的直接前路入路具有更早的恢复和更好的预后,但我们的研究结果表明,与直接外侧入路相比,该入路可能具有更大的早期股骨衰竭风险,并且与后路入路一起,具有更大的早期不稳定风险。证据等级:治疗性III级。有关证据水平的完整描述,请参见作者说明。
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引用次数: 98
Nonoperatively Corrected Clubfoot at Age 2 Years: Radiographs Are Not Helpful in Predicting Future Relapse 2岁非手术矫正畸形足:x线片对预测未来复发没有帮助
Pub Date : 2017-01-18 DOI: 10.2106/JBJS.16.00693
B. S. Richards, Shawne Faulks, Ozan Razi, Amanda Moualeu, C. Jo
Background: Nonoperative treatment of idiopathic clubfoot is standard. The purpose of this study was to determine if measurements made on standing lateral radiographs of successfully treated clubfeet made at 18 to 24 months of age were predictive of late recurrence. Methods: Inclusion criteria were idiopathic clubfoot with an age at presentation of ⩽3 months, nonoperative treatment resulting in a clinically plantigrade foot at 2 years of age, standing lateral radiograph of the involved foot made at 18 to 24 months of age, and a minimum age of 4 years at the time of follow-up. The radiographs were assessed for the talocalcaneal angle and the tibiocalcaneal angle, with measurements made by 2 trained practitioners. The average values of the 2 raters were used. The interobserver reliability was calculated using intraclass correlation coefficients (ICCs). A total of 211 patients with 312 clubfeet were evaluated. The average age at the time of follow-up was 8.0 years (range, 4.0 to 13.3 years). Results at the time of follow-up were rated as good (maintained plantigrade foot), fair (required limited surgery to maintain, or return to, a plantigrade position), or poor (required posteromedial release). Results: Over time, 75% of the feet had a good result, 19% had a fair result, and 6% had a poor result. With regard to radiographic assessment, the ICCs were 0.97 (talocalcaneal angle) and 0.98 (tibiocalcaneal angle), demonstrating excellent agreement between the raters. The mean talocalcaneal angle differed significantly between the feet with a good clinical outcome and those with a fair outcome (28° versus 24°; p < 0.02), but did not differ significantly between those with a good versus poor outcome (28° versus 26°), or a fair versus poor outcome (24° versus 26°). There were no significant differences in the mean tibiocalcaneal angle among the groups (86°, 90°, and 84°, respectively) (p = 0.17). Conclusions: Most clubfeet that were clinically plantigrade at 2 years of age remained so, while one-fourth subsequently required some surgery for late recurrence, primarily limited procedures. The tibiocalcaneal angle and talocalcaneal angle from standing lateral radiographs made at 18 to 24 months of age were not helpful in predicting future relapse. Level of Evidence: Prognostic Level IV. See Instructions for Authors for a complete description of levels of evidence.
背景:非手术治疗特发性内翻足是标准的。本研究的目的是确定18 ~ 24月龄成功治疗的马蹄内翻足的站立侧位x线片是否能预测晚期复发。方法:纳入标准为特发性内翻足,发病年龄≥3个月,2岁时非手术治疗导致临床跖足,18 - 24个月时受病足站立侧位x线片,随访时最小年龄为4岁。x线片评估距骨跟角和胫骨跟角,由2名训练有素的医生测量。取2个评分者的平均值。使用类内相关系数(ICCs)计算观察者间信度。共对211例312例内翻足患者进行评估。随访时的平均年龄为8.0岁(范围为4.0 ~ 13.3岁)。随访时的结果被评为良好(维持跖屈足),一般(需要有限的手术来维持或恢复跖屈足位置)或差(需要后内侧释放)。结果:随着时间的推移,75%的脚有良好的结果,19%的脚有一般的结果,6%的脚有不好的结果。在影像学评估方面,ICCs分别为0.97(距跟角)和0.98(胫跟角),显示了评分者之间的良好一致性。临床结果良好的足部和临床结果一般的足部的距跟平均角度差异显著(28°vs 24°;P < 0.02),但结果好与差(28°对26°)或结果一般与差(24°对26°)之间无显著差异。两组间胫跟平均角度(分别为86°、90°和84°)差异无统计学意义(p = 0.17)。结论:大多数在2岁时临床表现为足底退化的内翻足仍然如此,而四分之一的患者随后需要一些手术治疗晚期复发,主要是有限的手术。18 ~ 24月龄站立侧位片胫骨跟骨角和距跟骨角对预测未来复发没有帮助。证据等级:预后IV级。参见《作者说明》获得证据等级的完整描述。
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引用次数: 15
Comparison of Ultrasound and MRI for the Diagnosis of Glenohumeral Dysplasia in Brachial Plexus Birth Palsy 超声与MRI诊断臂丛出生性麻痹肩关节发育不良的比较
Pub Date : 2017-01-18 DOI: 10.2106/JBJS.15.01116
Kenneth Donohue, K. Little, J. Gaughan, S. Kozin, Brian D Norton, D. Zlotolow
Background: In this study, we investigated the agreement between measurements made on ultrasound and those made on magnetic resonance imaging (MRI) in the assessment of glenohumeral dysplasia resulting from brachial plexus birth palsy. Methods: Thirty-nine patients (14 male and 25 female) with brachial plexus birth palsy were evaluated at 2 tertiary care centers. All patients underwent ultrasonography and MRI for suspected glenohumeral dysplasia. Studies were obtained at an average of 2 months apart (range, 0 to 6 months). The average patient age at the time of the initial imaging study was 20 months (range, 4 to 54 months). Four blinded independent evaluators measured the alpha angle, the posterior humeral head displacement (PHHD), and glenoid version on both the ultrasound and MRI study for each patient. The percentage of the humeral head anterior to the scapular axis (PHHA) was determined on MRI only. Measurements were obtained on OsiriX software (Pixmeo). Intraclass correlation coefficients (ICCs) were used to assess the intrarater and interrater reliability, and Bland-Altman plots were used to compare MRI and ultrasound measurement agreement. Results: We found excellent interrater reliability for measurements of the alpha angle on MRI, glenoid version on MRI, and the alpha angle on ultrasound (ICC: 0.83, 0.75, and 0.78, respectively). The interrater reliability for the PHHD on both MRI and ultrasound was good (ICC: 0.70 and 0.68, respectively), and the interrater reliability for the PHHA on MRI was fair (ICC: 0.57). However, the interrater reliability for glenoid version on ultrasound was poor (ICC: 0.30). Relative to MRI measurements, ultrasound measurements were found to underestimate the alpha angle and glenoid version by an average of 13° ± 23° and 6° ± 17°, respectively, and overestimate the PHHD by an average of 4% ± 20%. Increasing patient age corresponded with a significant increase in the MRI-ultrasound measurement difference for the alpha angle (p < 0.01) and a marginally significant increase in the difference for the PHHD (p < 0.06). Conclusions: Measurements on MRI and ultrasound were reliable, with measured bias. The poor agreement between measurements on MRI and ultrasound calls into question the validity of using ultrasonography as a stand-alone modality in the evaluation of glenohumeral dysplasia. MRI remains the gold standard for fully evaluating the glenohumeral joint. The clinical role of ultrasonography may be that of a screening tool or a way of evaluating joint reduction in real time. Level of Evidence: Diagnostic Level I. See Instructions for Authors for a complete description of levels of evidence.
背景:在本研究中,我们调查了超声测量结果与磁共振成像(MRI)测量结果在评估臂丛出生性麻痹导致的肩关节发育不良时的一致性。方法:对39例臂丛分娩性麻痹患者(男14例,女25例)在2个三级保健中心进行评估。所有患者均行超声及MRI检查,怀疑为盂肱发育不良。研究平均间隔2个月(范围,0至6个月)。患者在初始影像学检查时的平均年龄为20个月(范围4至54个月)。四名独立的盲法评估者在超声和MRI研究中测量了每位患者的α角、肱骨后头位移(PHHD)和肩胛盂变形。肩胛骨轴前肱骨头(PHHA)的百分比仅通过MRI确定。测量结果在OsiriX软件(Pixmeo)上获得。分类内相关系数(ICCs)用于评估分类内和分类间的可靠性,Bland-Altman图用于比较MRI和超声测量的一致性。结果:我们发现MRI上的α角测量、MRI上的关节盂版本和超声上的α角测量具有出色的相互可靠性(ICC分别为0.83、0.75和0.78)。PHHA在MRI和超声上的互传信度均较好(ICC分别为0.70和0.68),在MRI上的互传信度为一般(ICC为0.57)。然而,超声对关节盂版本的判读可靠性较差(ICC: 0.30)。与MRI测量结果相比,超声测量结果分别平均低估了α角和关节盂形状13°±23°和6°±17°,平均高估了PHHD 4%±20%。随着患者年龄的增加,mri超声测量α角的差异显著增加(p < 0.01), PHHD的差异略有显著增加(p < 0.06)。结论:MRI和超声测量结果可靠,存在测量偏差。MRI和超声测量结果之间的不一致使超声作为评估盂肱发育不良的独立方式的有效性受到质疑。MRI仍然是全面评估盂肱关节的金标准。超声的临床作用可能是一种筛查工具或一种实时评估关节复位的方法。证据级别:诊断级i。参见《作者指南》获得证据级别的完整描述。
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引用次数: 14
Three-Dimensional Analysis of Acute Scaphoid Fracture Displacement: Proximal Extension Deformity of the Scaphoid 急性舟状骨骨折移位的三维分析:舟状骨近端延伸畸形
Pub Date : 2017-01-18 DOI: 10.2106/JBJS.16.00021
Yonatan Schwarcz, Y. Schwarcz, E. Peleg, Leo Joskowicz, R. Wollstein, S. Luria
Background: Our goal was to analyze the movement of acute scaphoid waist fracture fragments and adjacent bones in a common coordinate system. Our hypothesis was that the distal scaphoid fragment flexes and pronates and the proximal fragment extends. Methods: Computed tomography (CT) scans of patients diagnosed with an acute scaphoid waist fracture were evaluated using a 3-dimensional (3D) model. The scans of 57 nondisplaced and 23 displaced fractures were compared with a control group of 27 scans showing no pathological involvement of the wrist. Three anatomical landmarks were labeled on the distal and proximal fragments of the scaphoid, the lunate, and the trapezium. Each set of labels formed a triangle representing the bone or fragment. Four landmarks were labeled on the distal radial articular surface and used to create a common coordinate system. The position of each bone or fragment was calculated in reference to these coordinates. Results: The displaced fracture group showed significant extension, supination, and volar translation of the proximal scaphoid fragment when compared with the other groups. The lunate tended toward a supinated position, which was not statistically significant. The distal scaphoid fragment and the trapezium showed no movement. Conclusions: In acute displaced scaphoid fractures, it is the proximal fragment that displaces and should be reduced. Clinical Relevance: The typical “humpback” deformity is actually a “proximal extension” deformity, the consequence of displacement of the proximal fragment of the scaphoid (with the lunate). Manipulating only the proximal fragment (with the lunate) may be technically easier and more effective than manipulating both fragments.
背景:我们的目的是分析急性舟状骨腰骨折碎片和相邻骨在一个共同坐标系中的运动。我们的假设是远端舟状骨碎片屈曲和旋前,近端舟状骨碎片伸展。方法:采用三维(3D)模型对诊断为急性舟状骨腰骨折患者的CT扫描结果进行评估。57例未移位骨折和23例移位骨折的扫描结果与对照组27例扫描结果进行了比较,结果显示腕部未受病理性影响。在舟状骨、月骨和斜方骨的远端和近端碎片上标记了三个解剖标志。每组标签形成一个三角形,代表骨头或碎片。在远端桡骨关节面标记四个地标,并用于创建一个共同的坐标系。每块骨头或碎片的位置都是根据这些坐标计算出来的。结果:移位骨折组与其他组相比,舟状骨近端碎片有明显的伸展、旋后和掌侧平移。月骨倾向于旋后位,差异无统计学意义。远端舟状骨碎片和斜方骨没有运动。结论:在急性移位的舟状骨骨折中,发生移位的是近端碎片,应复位。临床相关性:典型的“座头”畸形实际上是一种“近端延伸”畸形,是舟状骨近端碎片(与月骨)移位的结果。仅操作近端碎片(带月骨)在技术上可能比操作两个碎片更容易和更有效。
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引用次数: 16
National Institutes of Health Funding to Departments of Orthopaedic Surgery at U.S. Medical Schools 美国国立卫生研究院资助美国医学院整形外科部门
Pub Date : 2017-01-18 DOI: 10.2106/JBJS.16.00088
J. Silvestre, Jaimo Ahn, L. Scott Levin
Background: The National Institutes of Health (NIH) is the largest supporter of biomedical research in the U.S., yet its contribution to orthopaedic research is poorly understood. In this study, we analyzed the portfolio of NIH funding to departments of orthopaedic surgery at U.S. medical schools. Methods: The NIH RePORT (Research Portfolio Online Reporting Tools) database was queried for NIH grants awarded to departments of orthopaedic surgery in 2014. Funding totals were determined for award mechanisms and NIH institutes. Trends in NIH funding were determined for 2005 to 2014 and compared with total NIH extramural research funding. Funding awarded to orthopaedic surgery departments was compared with that awarded to departments of other surgical specialties in 2014. Characteristics of NIH-funded principal investigators were obtained from department web sites. Results: In 2014, 183 grants were awarded to 132 investigators at 44 departments of orthopaedic surgery. From 2005 to 2014, NIH funding increased 24.3%, to $54,608,264 (p = 0.030), but the rates of increase seen did not differ significantly from those of NIH extramural research funding as a whole (p = 0.141). Most (72.6%) of the NIH funding was awarded through the R01 mechanism, with a median annual award of $343,980 (interquartile range [IQR], $38,372). The majority (51.1%) of the total funds supported basic science research, followed by translational (33.0%), clinical (10.0%), and educational (5.9%) research. NIH-funded orthopaedic principal investigators were predominately scientists whose degree was a PhD (71.1%) and who were male (79.5%). Eleven NIH institutes were represented, with the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) providing the preponderance (74.2%) of the funding. In 2014, orthopaedic surgery ranked below the surgical departments of general surgery, ophthalmology, obstetrics and gynecology, otolaryngology, and urology in terms of NIH funding received. Conclusions: The percentage increase of NIH funding to departments of orthopaedic surgery from 2005 to 2014 was not significantly greater than that of total NIH extramural research funding. Funding levels to orthopaedic surgery departments lag behind funding to departments of other surgical disciplines. Funding levels may not match the academic potential of orthopaedic faculty, and interventions may be needed to increase NIH grant procurement.
背景:美国国立卫生研究院(NIH)是美国生物医学研究的最大支持者,但其对骨科研究的贡献却鲜为人知。在这项研究中,我们分析了美国国立卫生研究院对美国医学院骨科外科部门的资助组合。方法:查询NIH报告(研究组合在线报告工具)数据库中2014年授予骨科的NIH资助。资助总额由奖励机制和NIH研究所确定。确定了2005年至2014年NIH资助的趋势,并与NIH校外研究资助总额进行了比较。对比2014年骨科与其他外科专科的经费投入情况。美国国立卫生研究院资助的主要研究人员的特征从部门网站获得。结果:2014年共获得183笔资助,资助对象为骨科44个科室的132名研究者。从2005年到2014年,NIH经费增加了24.3%,达到54,608,264美元(p = 0.030),但增长率与NIH校外研究经费的总体增长率没有显著差异(p = 0.141)。大多数(72.6%)的NIH资金是通过R01机制授予的,年度奖金中位数为343,980美元(四分位数范围[IQR], 38,372美元)。其中,基础研究占51.1%,其次是转化研究(33.0%)、临床研究(10.0%)和教育研究(5.9%)。美国国立卫生研究院资助的骨科首席研究员主要是具有博士学位的科学家(71.1%)和男性(79.5%)。美国国立卫生研究院的11个研究所参加了会议,其中国家关节炎、肌肉骨骼和皮肤疾病研究所(NIAMS)提供了大部分(74.2%)资金。2014年,骨科获得的NIH经费排名在普外科、眼科、妇产科、耳鼻喉科和泌尿外科之后。结论:2005 - 2014年NIH对骨科的经费增长百分比不显著大于NIH校外科研经费增长百分比。骨科的经费水平落后于其他外科学科的经费。资助水平可能与骨科教师的学术潜力不匹配,可能需要干预措施来增加NIH的资助采购。
{"title":"National Institutes of Health Funding to Departments of Orthopaedic Surgery at U.S. Medical Schools","authors":"J. Silvestre, Jaimo Ahn, L. Scott Levin","doi":"10.2106/JBJS.16.00088","DOIUrl":"https://doi.org/10.2106/JBJS.16.00088","url":null,"abstract":"Background: The National Institutes of Health (NIH) is the largest supporter of biomedical research in the U.S., yet its contribution to orthopaedic research is poorly understood. In this study, we analyzed the portfolio of NIH funding to departments of orthopaedic surgery at U.S. medical schools. Methods: The NIH RePORT (Research Portfolio Online Reporting Tools) database was queried for NIH grants awarded to departments of orthopaedic surgery in 2014. Funding totals were determined for award mechanisms and NIH institutes. Trends in NIH funding were determined for 2005 to 2014 and compared with total NIH extramural research funding. Funding awarded to orthopaedic surgery departments was compared with that awarded to departments of other surgical specialties in 2014. Characteristics of NIH-funded principal investigators were obtained from department web sites. Results: In 2014, 183 grants were awarded to 132 investigators at 44 departments of orthopaedic surgery. From 2005 to 2014, NIH funding increased 24.3%, to $54,608,264 (p = 0.030), but the rates of increase seen did not differ significantly from those of NIH extramural research funding as a whole (p = 0.141). Most (72.6%) of the NIH funding was awarded through the R01 mechanism, with a median annual award of $343,980 (interquartile range [IQR], $38,372). The majority (51.1%) of the total funds supported basic science research, followed by translational (33.0%), clinical (10.0%), and educational (5.9%) research. NIH-funded orthopaedic principal investigators were predominately scientists whose degree was a PhD (71.1%) and who were male (79.5%). Eleven NIH institutes were represented, with the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) providing the preponderance (74.2%) of the funding. In 2014, orthopaedic surgery ranked below the surgical departments of general surgery, ophthalmology, obstetrics and gynecology, otolaryngology, and urology in terms of NIH funding received. Conclusions: The percentage increase of NIH funding to departments of orthopaedic surgery from 2005 to 2014 was not significantly greater than that of total NIH extramural research funding. Funding levels to orthopaedic surgery departments lag behind funding to departments of other surgical disciplines. Funding levels may not match the academic potential of orthopaedic faculty, and interventions may be needed to increase NIH grant procurement.","PeriodicalId":22579,"journal":{"name":"The Journal of Bone and Joint Surgery","volume":"26 1","pages":"e5"},"PeriodicalIF":0.0,"publicationDate":"2017-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91511933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 25
Unicompartmental Knee Arthroplasty Provides Higher Activity and Durability Than Valgus-Producing Proximal Tibial Osteotomy at 5 to 7 Years 单室膝关节置换术在5 - 7年内比产生外翻的胫骨近端截骨术具有更高的活动性和耐久性
Pub Date : 2017-01-18 DOI: 10.2106/JBJS.15.01031
A. Krych, Patrick J. Reardon, Paul L. Sousa, Ayoosh Pareek, M. Stuart, M. Pagnano
Background: The cases of patients with medial compartment osteoarthritis who were ⩽55 years old and had a proximal tibial osteotomy (PTO) or medial unicompartmental knee arthroplasty (UKA) were compared. Outcomes included postoperative activity level, function, and survivorship free of revision to total knee arthroplasty. Methods: Between 1998 and 2013, data were available for 240 patients between 18 and 55 years old with medial compartment arthritis and varus malalignment who were treated either with PTO (57 patients) or with UKA (183 patients). The mean age was 42.7 years for the 57 patients (41 men and 16 women) in the PTO group versus 49.2 years for the 183 patients (82 men and 101 women) in the UKA group. The Tegner activity level and Lysholm knee scores were evaluated at 3 months and at 1, 2, and 5 years postoperatively as well as at the time of the final follow-up. The end point for survival was defined as revision to total knee arthroplasty. A Wilcoxon rank-sum test was used to evaluate the difference between the groups with respect to the Tegner and Lysholm scores at the respective follow-up intervals. Multivariate regression was used to assess potential confounders. Results: Preoperatively, the PTO and UKA groups had similar Tegner (3.0 ± 1.3 and 2.6 ± 0.09, respectively) and Lysholm scores (69.5 ± 7.3 and 71.6 ± 5.4). Postoperatively, the UKA group had significantly superior mean Tegner scores compared with the PTO group at 3 months (3.82 and 2.02, respectively), at 2 years (4.33 and 3.75), and at the time of the final follow-up (4.48 and 3.08), while the Lysholm scores were higher at 3 months (88.0 and 76.3) and at the final follow-up (90.0 and 80.2) (p < 0.01 for all). Multivariate analysis showed UKA to be an independent predictor of activity level at 3 months, 1 year, and 2 years, as well as at the final follow-up. The survivorship was 77% in the PTO group at an average of 7.2 years and 94% in the UKA group at an average of 5.8 years (p < 0.01). The average time to failure was 98 months (range, 38 to 169 months) in the PTO group and 42 months (range, 2 to 123 months) in the UKA group (p < 0.01). Conclusions: In this comparative cohort study of young patients with isolated unicompartmental arthritis, those treated with UKA reached a higher level of activity early after surgery and it persisted at mid-term follow-up. The UKA group had earlier, but less frequent, revision to total knee arthroplasty. Level of Evidence: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
背景:对年龄≥55岁且行胫骨近端截骨术(PTO)或内侧单室膝关节置换术(UKA)的内侧室骨关节炎患者进行比较。结果包括术后活动水平、功能和无翻修全膝关节置换术的生存率。方法:在1998年至2013年期间,240例18至55岁的内侧隔室关节炎和内翻错位患者接受PTO(57例)或UKA(183例)治疗。PTO组57名患者(41名男性和16名女性)的平均年龄为42.7岁,而UKA组183名患者(82名男性和101名女性)的平均年龄为49.2岁。在术后3个月、1年、2年和5年以及最后随访时评估Tegner活动水平和Lysholm膝关节评分。生存终点定义为全膝关节置换术后的翻修。采用Wilcoxon秩和检验来评估两组在各自随访时间间隔内Tegner和Lysholm评分的差异。采用多元回归评估潜在混杂因素。结果:术前PTO组和UKA组Tegner评分(分别为3.0±1.3和2.6±0.09)和Lysholm评分(分别为69.5±7.3和71.6±5.4)相近。术后3个月(分别为3.82和2.02)、2年(分别为4.33和3.75)和末次随访时(分别为4.48和3.08),UKA组的平均Tegner评分显著高于PTO组,而Lysholm评分在3个月(分别为88.0和76.3)和末次随访时(分别为90.0和80.2)均高于PTO组(p < 0.01)。多变量分析显示,UKA是3个月、1年、2年以及最后随访时活动水平的独立预测因子。PTO组生存率为77%,平均7.2年;UKA组生存率为94%,平均5.8年(p < 0.01)。PTO组平均失效时间为98个月(38 ~ 169个月),UKA组平均失效时间为42个月(2 ~ 123个月)(p < 0.01)。结论:在这项针对孤立性单室关节炎的年轻患者的比较队列研究中,接受UKA治疗的患者术后早期活动水平较高,并在中期随访中持续存在。UKA组的全膝关节置换术翻修时间较早,但频率较低。证据等级:治疗性III级。有关证据水平的完整描述,请参见作者说明。
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引用次数: 44
Characterizing the Propionibacterium Load in Revision Shoulder Arthroplasty: A Study of 137 Culture-Positive Cases 肩关节翻修成形术中丙酸杆菌负荷的特征:137例培养阳性病例的研究
Pub Date : 2017-01-18 DOI: 10.2106/JBJS.16.00422
Zahab S. Ahsan, J. Somerson, Frederick A Matsen
Background: Propionibacterium is commonly recovered from explants or surrounding tissues in revision shoulder arthroplasty. Rather than attempting to differentiate a true infection from a false-positive result on the basis of the number of positive cultures, we characterized the amount of these bacteria in each specimen and shoulder. Methods: The study included 137 revision shoulder arthroplasties from which a minimum of 4 specimens had been submitted for culture and at least 1 was positive for Propionibacterium. Standard microbiology procedures were used to assign a semiquantitative value (0.1, 1, 2, 3, or 4), called the Specimen Propi Value, to the amount of growth in each specimen. The sum of the Specimen Propi Values for each shoulder was defined as the Shoulder Propi Score, which was then divided by the total number of specimens to calculate the Average Shoulder Propi Score. Results: The number and percentage of positive specimen-specific cultures (of material obtained from the stem explant, head explant, glenoid explant, humeral membrane, collar membrane, other soft tissue, fluid, or other) per shoulder ranged from 1 to 6 and 14% to 100%. A high percentage of specimens (mean, 43%; median, 50%) from the culture-positive shoulders showed no growth. Only 32.6% of the fluid cultures were positive in comparison with 66.5% of the soft-tissue cultures and 55.6% of the cultures of explant specimens. The average Specimen Propi Value (and standard deviation) for fluid specimens (0.35 ± 0.89) was significantly lower than those for the soft-tissue (0.92 ± 1.50) and explant (0.66 ± 0.90) specimens (p < 0.001). The Shoulder Propi Score was significantly higher in men (3.56 ± 3.74) than in women (1.22 ± 3.11) (p < 0.001). Similarly, men had a significantly higher Average Shoulder Propi Score (0.53 ± 0.51) than women (0.19 ± 0.43) (p < 0.001). Conclusions: This investigation suggests that Propionibacterium is unevenly distributed within culture-positive revised shoulders. As a result, the specimen number and source (explant, soft tissue, or fluid) have major influences on the culture results for a revised shoulder arthroplasty. We found no evidence that suggested useful threshold values for defining a true infection. Level of Evidence: Diagnostic Level III. See Instructions for Authors for a complete description of levels of evidence.
背景:翻修肩关节置换术中,丙酸杆菌通常从外植体或周围组织中恢复。我们不是试图根据阳性培养的数量来区分真实感染和假阳性结果,而是对每个标本和肩部中这些细菌的数量进行表征。方法:本研究纳入137例翻修肩关节置换术,其中至少4例标本已提交培养,至少1例丙酸杆菌阳性。使用标准微生物学程序为每个标本中的生长量指定一个半定量值(0.1、1、2、3或4),称为标本Propi值。每个肩部的标本Propi值之和被定义为肩部Propi评分,然后将其除以标本总数计算平均肩部Propi评分。结果:每个肩部标本特异性培养阳性的数量和百分比(从茎外植体、头外植体、肩关节外植体、肱骨膜、颈膜、其他软组织、液体或其他组织中获得的材料)范围为1至6和14%至100%。标本的比例很高(平均43%;中位数为50%),培养阳性肩部未见生长。液体培养阳性率为32.6%,而软组织培养阳性率为66.5%,外植体标本培养阳性率为55.6%。液体标本的平均Propi值(及标准差)为0.35±0.89,显著低于软组织标本(0.92±1.50)和外植体标本(0.66±0.90)(p < 0.001)。肩关节支撑评分男性(3.56±3.74)明显高于女性(1.22±3.11)(p < 0.001)。同样,男性的平均肩支撑评分(0.53±0.51)明显高于女性(0.19±0.43)(p < 0.001)。结论:本研究提示丙酸杆菌在培养阳性的肩部内分布不均匀。因此,标本数量和来源(外植体、软组织或液体)对改良肩关节置换术的培养结果有主要影响。我们没有发现任何证据表明定义真正感染的有用阈值。证据等级:诊断级III。有关证据水平的完整描述,请参见作者说明。
{"title":"Characterizing the Propionibacterium Load in Revision Shoulder Arthroplasty: A Study of 137 Culture-Positive Cases","authors":"Zahab S. Ahsan, J. Somerson, Frederick A Matsen","doi":"10.2106/JBJS.16.00422","DOIUrl":"https://doi.org/10.2106/JBJS.16.00422","url":null,"abstract":"Background: Propionibacterium is commonly recovered from explants or surrounding tissues in revision shoulder arthroplasty. Rather than attempting to differentiate a true infection from a false-positive result on the basis of the number of positive cultures, we characterized the amount of these bacteria in each specimen and shoulder. Methods: The study included 137 revision shoulder arthroplasties from which a minimum of 4 specimens had been submitted for culture and at least 1 was positive for Propionibacterium. Standard microbiology procedures were used to assign a semiquantitative value (0.1, 1, 2, 3, or 4), called the Specimen Propi Value, to the amount of growth in each specimen. The sum of the Specimen Propi Values for each shoulder was defined as the Shoulder Propi Score, which was then divided by the total number of specimens to calculate the Average Shoulder Propi Score. Results: The number and percentage of positive specimen-specific cultures (of material obtained from the stem explant, head explant, glenoid explant, humeral membrane, collar membrane, other soft tissue, fluid, or other) per shoulder ranged from 1 to 6 and 14% to 100%. A high percentage of specimens (mean, 43%; median, 50%) from the culture-positive shoulders showed no growth. Only 32.6% of the fluid cultures were positive in comparison with 66.5% of the soft-tissue cultures and 55.6% of the cultures of explant specimens. The average Specimen Propi Value (and standard deviation) for fluid specimens (0.35 ± 0.89) was significantly lower than those for the soft-tissue (0.92 ± 1.50) and explant (0.66 ± 0.90) specimens (p < 0.001). The Shoulder Propi Score was significantly higher in men (3.56 ± 3.74) than in women (1.22 ± 3.11) (p < 0.001). Similarly, men had a significantly higher Average Shoulder Propi Score (0.53 ± 0.51) than women (0.19 ± 0.43) (p < 0.001). Conclusions: This investigation suggests that Propionibacterium is unevenly distributed within culture-positive revised shoulders. As a result, the specimen number and source (explant, soft tissue, or fluid) have major influences on the culture results for a revised shoulder arthroplasty. We found no evidence that suggested useful threshold values for defining a true infection. Level of Evidence: Diagnostic Level III. See Instructions for Authors for a complete description of levels of evidence.","PeriodicalId":22579,"journal":{"name":"The Journal of Bone and Joint Surgery","volume":"31 1","pages":"150–154"},"PeriodicalIF":0.0,"publicationDate":"2017-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76036680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 48
The Core Competencies for General Orthopaedic Surgeons 普通骨科医生的核心能力
Pub Date : 2017-01-18 DOI: 10.2106/JBJS.16.00761
J. Kellam, D. Archibald, J. W. Barber, E. P. Christian, Richard J. D’Ascoli, R. Haynes, S. Hecht, S. Hurwitz, A. McLaren, T. Peabody, S. Southworth, R. Strauss, V. Wadey
Background: With the changing delivery of orthopaedic surgical care, there is a need to define the knowledge and competencies that are expected of an orthopaedist providing general and/or acute orthopaedic care. This article provides a proposal for the knowledge and competencies needed for an orthopaedist to practice general and/or acute care orthopaedic surgery. Methods: Using the modified Delphi method, the General Orthopaedic Competency Task Force consisting of stakeholders associated with general orthopaedic practice has proposed the core knowledge and competencies that should be maintained by orthopaedists who practice emergency and general orthopaedic surgery. Results: For relevancy to clinical practice, 2 basic sets of competencies were established. The assessment competencies pertain to the general knowledge needed to evaluate, investigate, and determine an overall management plan. The management competencies are generally procedural in nature and are divided into 2 groups. For the Management 1 group, the orthopaedist should be competent to provide definitive care including assessment, investigation, initial or emergency care, operative or nonoperative care, and follow-up. For the Management 2 group, the orthopaedist should be competent to assess, investigate, and commence timely non-emergency or emergency care and then either transfer the patient to the appropriate subspecialist’s care or provide definitive care based on the urgency of care, exceptional practice circumstance, or individual’s higher training. This may include some higher-level procedures usually performed by a subspecialist, but are consistent with one’s practice based on experience, practice environment, and/or specialty interest. Conclusions: These competencies are the first step in defining the practice of general orthopaedic surgery including acute orthopaedic care. Further validation and discussion among educators, general orthopaedic surgeons, and subspecialists will ensure that these are relevant to clinical practice. Clinical Relevance: These competencies provide many stakeholders, including orthopaedic educators and orthopaedists, with what may be the minimum knowledge and competencies necessary to deliver acute and general orthopaedic care. This document is the first step in defining a practice-based standard for training programs and certification groups.
背景:随着骨科手术护理方式的变化,需要明确骨科医生提供普通和/或急性骨科护理的知识和能力。这篇文章提供了一个建议的知识和能力,需要骨科医生实践一般和/或急性护理骨科手术。方法:采用改进的德尔菲法,由与普通骨科实践相关的利益相关者组成的普通骨科能力工作组提出了从事急诊和普通骨科手术的骨科医生应保持的核心知识和能力。结果:建立了与临床实践相关的2套基本胜任力。评估能力涉及评估、调查和确定总体管理计划所需的一般知识。管理能力一般是程序性的,分为两组。对于管理1组,骨科医生应该有能力提供明确的护理,包括评估、调查、初始或紧急护理、手术或非手术护理和随访。对于管理2组,骨科医生应该有能力评估、调查并及时开始非急诊或急诊护理,然后将患者转移到适当的专科护理,或根据护理的紧迫性、特殊的实践情况或个人的高等培训提供最终护理。这可能包括一些通常由专科医生执行的高级程序,但与基于经验、实践环境和/或专业兴趣的实践相一致。结论:这些能力是定义普通骨科手术包括急性骨科护理实践的第一步。教育者、普通骨科医生和专科医生之间的进一步验证和讨论将确保这些与临床实践相关。临床相关性:这些能力为包括骨科教育者和骨科医生在内的许多利益相关者提供了提供急性和一般骨科护理所需的最低知识和能力。本文档是为培训项目和认证组织定义基于实践的标准的第一步。
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引用次数: 23
Low-Dose Aspirin Is Effective Chemoprophylaxis Against Clinically Important Venous Thromboembolism Following Total Joint Arthroplasty: A Preliminary Analysis 低剂量阿司匹林是预防全关节置换术后静脉血栓栓塞的有效药物:初步分析
Pub Date : 2017-01-18 DOI: 10.2106/JBJS.16.00147
J. Parvizi, Ronald C. Huang, C. Restrepo, Antonia F Chen, M. Austin, W. Hozack, J. Lonner
Background: Aspirin is a safe and effective prophylaxis for the prevention of venous thromboembolism following total joint arthroplasty. The optimal dose of aspirin prophylaxis is unknown. Our hypothesis was that lower-dose aspirin is as effective as higher-dose aspirin for the prevention of venous thromboembolism and is associated with fewer gastrointestinal side effects. Methods: In a prospective, crossover study, we analyzed 4,651 primary total joint arthroplasty cases performed from July 2013 to June 2015. For 4 weeks, 3,192 patients received enteric-coated 325-mg aspirin twice daily (the 325-mg aspirin group) and 1,459 patients received 81-mg aspirin twice daily (the 81-mg aspirin group). There were no significant differences (p > 0.05) in sex, body mass index, or Charlson Comorbidity Index between the two patient populations. Recorded complications occurring within 90 days postoperatively included symptomatic venous thromboembolism (deep venous thrombosis and pulmonary embolism), gastrointestinal complications, acute periprosthetic joint infection, and death. Results: The incidence of venous thromboembolism of 0.1% (95% confidence interval [CI], 0% to 0.3%) in the 81-mg aspirin group (1 with deep venous thrombosis and 1 with pulmonary embolism) was not significantly different (p = 0.345) from 0.3% (95% CI, 0.1% to 0.6%) in the 325-mg aspirin group (7 with deep venous thrombosis and 5 with pulmonary embolism). The incidence of gastrointestinal bleeding or ulceration of 0.3% (95% CI, 0% to 0.5%) in the 81-mg aspirin group was slightly, but not significantly (p = 0.66), lower than the 0.4% (95% CI, 0.2% to 0.6%) in the 325-mg aspirin group. The incidence of acute periprosthetic joint infection was 0.2% (95% CI, 0% to 0.4%) in the 81-mg aspirin group compared with 0.5% (95% CI, 0.2% to 0.7%) in the 325-mg aspirin group (p = 0.28). The 90-day mortality rate was similar in both groups at 0.1% (95% CI, 0% to 0.2%) in the 81-mg aspirin group and 0.1% (95% CI, 0% to 0.2%) in the 325-mg aspirin group (p = 0.78). Conclusions: Our study demonstrates that low-dose aspirin is not inferior to high-dose aspirin for venous thromboembolism prophylaxis following total joint arthroplasty. This is not unexpected, as the available literature demonstrates that low-dose aspirin is as effective as higher-dose aspirin in the prevention of acute coronary syndrome and cerebrovascular events. Level of Evidence: Therapeutic Level II. See Instructions for Authors for a complete description of levels of evidence.
背景:阿司匹林是一种安全有效的预防全关节置换术后静脉血栓栓塞的药物。阿司匹林预防的最佳剂量尚不清楚。我们的假设是,在预防静脉血栓栓塞方面,低剂量阿司匹林与高剂量阿司匹林同样有效,并且胃肠道副作用更少。方法:在一项前瞻性交叉研究中,我们分析了2013年7月至2015年6月期间进行的4,651例初次全关节置换术。在4周的时间里,3192名患者每天两次服用肠溶325毫克阿司匹林(325毫克阿司匹林组),1459名患者每天两次服用81毫克阿司匹林(81毫克阿司匹林组)。两组患者的性别、体重指数、Charlson合并症指数差异均无统计学意义(p > 0.05)。术后90天内记录的并发症包括症状性静脉血栓栓塞(深静脉血栓和肺栓塞)、胃肠道并发症、急性假体周围关节感染和死亡。结果:81 mg阿司匹林组(1例深静脉血栓形成,1例肺栓塞)的静脉血栓栓塞发生率为0.1%(95%可信区间[CI], 0% ~ 0.3%),与325 mg阿司匹林组(7例深静脉血栓形成,5例肺栓塞)的0.3% (95% CI, 0.1% ~ 0.6%)无显著差异(p = 0.345)。81毫克阿司匹林组的胃肠道出血或溃疡发生率为0.3% (95% CI, 0%至0.5%),略低于325毫克阿司匹林组的0.4% (95% CI, 0.2%至0.6%),但不显著(p = 0.66)。81 mg阿司匹林组的急性假体周围关节感染发生率为0.2% (95% CI, 0% ~ 0.4%),而325 mg阿司匹林组为0.5% (95% CI, 0.2% ~ 0.7%) (p = 0.28)。两组的90天死亡率相似,81毫克阿司匹林组为0.1% (95% CI, 0% - 0.2%), 325毫克阿司匹林组为0.1% (95% CI, 0% - 0.2%) (p = 0.78)。结论:我们的研究表明,在全关节置换术后静脉血栓栓塞预防方面,低剂量阿司匹林并不亚于高剂量阿司匹林。这并不意外,因为现有文献表明,在预防急性冠状动脉综合征和脑血管事件方面,低剂量阿司匹林与高剂量阿司匹林同样有效。证据等级:治疗性II级。有关证据水平的完整描述,请参见作者说明。
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引用次数: 97
Risk-Adjusted Hospital Outcomes in Medicare Total Joint Replacement Surgical Procedures 风险调整后的医疗保险全关节置换手术的医院结果
Pub Date : 2017-01-04 DOI: 10.2106/JBJS.15.01455
D. Fry, M. Pine, S. Nedza, David G. Locke, Agnes M. Reband, Gregory Pine
Background: Comparative measurement of hospital outcomes can define opportunities for care improvement and will assume great importance as alternative payment models for inpatient total joint replacement surgical procedures are introduced. The purpose of this study was to develop risk-adjusted models for Medicare inpatient and post-discharge adverse outcomes in elective lower-extremity total joint replacement and to apply these models for hospital comparison. Methods: Hospitals with ≥50 qualifying cases of elective total hip replacement and total knee replacement from the Medicare Limited Data Set database of 2010 to 2012 were studied. Logistic risk models were designed for adverse outcomes of inpatient mortality, prolonged length-of-stay outliers in the index hospitalization, 90-day post-discharge deaths without readmission, and 90-day readmissions after excluding non-related readmissions. For each hospital, models were used to predict total adverse outcomes, the number of standard deviations from the mean (z-scores) for hospital performance, and risk-adjusted adverse outcomes for each hospital. Results: A total of 253,978 patients who underwent total hip replacement and 672,515 patients who underwent total knee replacement were studied. The observed overall adverse outcome rates were 12.0% for total hip replacement and 11.6% for total knee replacement. The z-scores for 1,483 hospitals performing total hip replacements varied from −5.09 better than predicted to +5.62 poorer than predicted; 98 hospitals were ≥2 standard deviations better than predicted and 142 hospitals were ≥2 standard deviations poorer than predicted. The risk-adjusted adverse outcome rate for these hospitals was 6.6% for the best-decile hospitals and 19.8% for the poorest-decile hospitals. The z-scores for the 2,349 hospitals performing total knee replacements varied from −5.85 better than predicted to +11.75 poorer than predicted; 223 hospitals were ≥2 standard deviations better than predicted and 319 hospitals were ≥2 standard deviations poorer than predicted. The risk-adjusted adverse outcome rate for these hospitals was 6.4% for the best-decile hospitals and 19.3% for the poorest-decile hospitals. Conclusions: Risk-adjusted outcomes demonstrate wide variability and illustrate the need for improvement among poorer-performing hospitals for bundled payments of joint replacement surgical procedures. Clinical Relevance: Adverse outcomes are known to occur in the experience of all clinicians and hospitals. The risk-adjusted benchmarking of hospital performance permits the identification of adverse events that are potentially preventable.
背景:医院结果的比较测量可以定义护理改善的机会,并且随着住院患者全关节置换手术的替代支付模式的引入,将具有重要意义。本研究的目的是为选择性下肢全关节置换术的医疗保险住院和出院后不良后果建立风险调整模型,并将这些模型应用于医院比较。方法:选取2010 - 2012年医疗保险有限数据集数据库中≥50例符合条件的选择性全髋关节置换术和全膝关节置换术的医院为研究对象。针对住院死亡率、指数住院时间异常值延长、出院后90天无再入院死亡和排除非相关再入院后90天再入院等不良结局设计了Logistic风险模型。对于每家医院,使用模型来预测总不良结局、医院表现的均值标准差数(z-score)以及每家医院的风险调整不良结局。结果:共研究了253,978例全髋关节置换术患者和672,515例全膝关节置换术患者。观察到全髋关节置换术的总体不良结局发生率为12.0%,全膝关节置换术的不良结局发生率为11.6%。1,483家进行全髋关节置换术的医院的z分数从比预测好- 5.09到比预测差+5.62不等;98家医院优于预测≥2个标准差,142家医院差于预测≥2个标准差。这些医院经风险调整后的不良转归率,最好的十分位数医院为6.6%,最差的十分位数医院为19.8%。2349家进行全膝关节置换术的医院的z分数从比预测好- 5.85到比预测差+11.75不等;223家医院优于预测≥2个标准差,319家医院差于预测≥2个标准差。这些医院经风险调整后的不良转归率,最好的十分位数医院为6.4%,最差的十分位数医院为19.3%。结论:风险调整后的结果表现出广泛的可变性,并说明在表现较差的医院中,需要改进关节置换手术的捆绑支付。临床相关性:在所有临床医生和医院的经验中,已知会发生不良后果。医院绩效的风险调整基准允许识别潜在可预防的不良事件。
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引用次数: 26
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The Journal of Bone and Joint Surgery
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