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Single-Anesthetic Versus Staged Bilateral Total Hip Arthroplasty: A Matched Cohort Study 单麻醉与分期双侧全髋关节置换术:一项匹配队列研究
Pub Date : 2017-01-04 DOI: 10.2106/JBJS.15.01223
M. Houdek, C. Wyles, C. Watts, E. Wagner, R. Sierra, R. Trousdale, M. Taunton
Background: There is debate regarding the role of single-anesthetic versus staged bilateral total hip arthroplasty (THA) for patients with end-stage bilateral osteoarthritis. Studies have shown that single-anesthetic bilateral THA is associated with systemic complications, but there are limited data comparing patient outcomes in a matched setting of bilateral THA. Methods: We identified 94 patients (188 hips) who underwent single-anesthetic bilateral THA. Fifty-seven percent of the patients were male. Patients had a mean age of 52.2 years and body mass index of 27.1 kg/m2. They were matched 1:1 on the basis of sex, age (±1 year), and year of surgery (±3 years) to a cohort of patients undergoing staged bilateral THA. In the staged group, there was <1 year between procedures (range, 5 days to 10 months). Mean follow-up was 4 years for each group. Results: Patients in the single-anesthetic group experienced shorter total operating room time and length of stay. There was no difference (hazard ratio [HR] = 0.73, p = 0.50) in the overall revision-free survival in patients undergoing single-anesthetic or staged bilateral THA. The risks of reoperation (HR = 0.69, p = 0.40), complications (HR = 0.83, p = 0.48), and mortality (HR = 0.47, p = 0.10) were similar. Single-anesthetic bilateral THA reduced the total cost of care (by 27%, p = 0.0001). Conclusions: In this matched cohort analysis, single-anesthetic bilateral THA was not associated with an increased risk of revision, reoperation, or postoperative complications, while decreasing cost. In our experience, single-anesthetic bilateral THA is a safe procedure that, for certain patients, offers an excellent means to deal with bilateral hip osteoarthritis. Level of Evidence: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
背景:对于终末期双侧骨关节炎患者,单麻醉与分期双侧全髋关节置换术(THA)的作用存在争议。研究表明,单麻醉双侧THA与全身并发症相关,但比较双侧THA匹配情况下患者预后的数据有限。方法:94例(188髋)行单麻醉双侧THA。57%的患者是男性。患者平均年龄52.2岁,体重指数27.1 kg/m2。他们根据性别、年龄(±1岁)和手术年份(±3岁)与接受分阶段双侧THA的患者进行1:1匹配。在分期组,手术间隔<1年(范围,5天至10个月)。每组平均随访4年。结果:单药组患者的总手术时间和住院时间较短。在接受单次麻醉或分阶段双侧THA的患者中,总体无修正生存期无差异(风险比[HR] = 0.73, p = 0.50)。再手术风险(HR = 0.69, p = 0.40)、并发症风险(HR = 0.83, p = 0.48)和死亡率(HR = 0.47, p = 0.10)相似。单麻醉双侧THA降低了总护理成本(27%,p = 0.0001)。结论:在这项匹配的队列分析中,单麻醉双侧THA与翻修、再手术或术后并发症的风险增加无关,同时降低了成本。根据我们的经验,单麻醉双侧全髋关节置换术是一种安全的手术,对某些患者来说,是治疗双侧髋关节骨关节炎的绝佳方法。证据等级:治疗性III级。有关证据水平的完整描述,请参见作者说明。
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引用次数: 30
Single Institution Early Experience with the Bundled Payments for Care Improvement Initiative 单一机构早期护理改善计划捆绑付款的经验
Pub Date : 2017-01-04 DOI: 10.2106/JBJS.16.00066
R. Iorio, J. Bosco, J. Slover, Yousuf Sayeed, J. Zuckerman
Abstract: The Centers for Medicare & Medicaid Services (CMS) implemented the Bundled Payments for Care Improvement (BPCI) initiative in 2011. Through BPCI, organizations enlisted into payment agreements that include both performance and financial accountability for episodes of care. To succeed, BPCI requires quality maintenance and care delivery at lower costs. This necessitates physicians and hospitals to merge interests. Orthopaedic surgeons must assume leadership roles in cost containment, surgical safety, and quality assurance to deliver cost-effective care. Because most orthopaedic surgeons practice independently and are not employed by hospitals, models of physician-hospital alignment (e.g., physician-hospital organizations) or contracted gainsharing arrangements between practices and hospitals may be necessary for successful bundled pricing. Under BPCI, hospitals, surgeons, or third parties share rewards but assume risks for the bundle. For patients, cost savings must be associated with maintenance or improvement in quality metrics. However, the definition of quality can vary, as can the rewards for processes and outcomes. Risk stratification for potential complications should be considered in bundled pricing agreements to prevent the exclusion of patients with substantial comorbidities and higher care costs (e.g., hip fractures treated with prostheses). Bundled pricing depends on economies of scale for success; smaller institutions must be cautious, as 1 costly patient could substantially impact the finances of its entire program. CMS recommends a minimum of 100 to 200 cases yearly. We also suggest that participants utilize technologies to maximize efficiency and provide the best possible environment for implementation of bundled payments. Substantial investment in infrastructure is required to develop programs to improve coordination of care, manage quality data, and distribute payments. Smaller institutions may have difficulty devoting resources to these infrastructural changes, although changes may be implemented more thoroughly once initiated. Herein, we discuss our early total joint arthroplasty BPCI experience at our tertiary-care academic medical center.
摘要:美国联邦医疗保险和医疗补助服务中心(CMS)于2011年实施了护理改善捆绑支付(BPCI)计划。通过BPCI,组织被纳入支付协议,包括对护理事件的绩效和财务责任。为了取得成功,BPCI需要以较低的成本提供高质量的维护和护理。这就需要医生和医院合并利益。骨科医生必须在成本控制、手术安全和质量保证方面发挥领导作用,以提供具有成本效益的护理。由于大多数骨科医生独立执业,不受雇于医院,因此医师-医院联合模式(例如,医师-医院组织)或医师和医院之间的合同收益分享安排可能是成功捆绑定价的必要条件。在BPCI下,医院、外科医生或第三方分享奖励,但承担捆绑治疗的风险。对于患者而言,成本节约必须与质量指标的维持或改进相关联。然而,质量的定义可以变化,过程和结果的奖励也可以变化。在捆绑定价协议中应考虑潜在并发症的风险分层,以防止排除有严重合并症和较高护理费用的患者(例如,用假体治疗髋部骨折)。捆绑定价的成功取决于规模经济;较小的机构必须谨慎,因为一个昂贵的病人可能会严重影响整个项目的财务状况。CMS建议每年至少做100到200例。我们还建议与会各方利用技术手段实现效率最大化,并为实施捆绑支付提供最佳环境。需要对基础设施进行大量投资,以制定改善护理协调、管理高质量数据和分配支付的计划。较小的机构可能难以将资源用于这些基础设施改革,尽管改革一旦开始实施可能会更彻底。在此,我们讨论我们在三级保健学术医疗中心的早期全关节置换术BPCI经验。
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引用次数: 62
Return to Function, Complication, and Reoperation Rates Following Primary Pectoralis Major Tendon Repair in Military Service Members 军人胸大肌肌腱修复术后功能恢复、并发症及再手术率
Pub Date : 2017-01-04 DOI: 10.2106/JBJS.16.00124
Drew W Nute, N. Kusnezov, J. Dunn, B. Waterman
Background: Pectoralis major tendon ruptures have become increasingly common injuries among young, active individuals over the past 30 years; however, there is presently a paucity of reported outcome data. We investigated the ability to return to full preoperative level of function, complications, reoperation rates, and risk factors for failure following surgical repair of the pectoralis major tendon in a cohort of young, highly active individuals. Methods: All U.S. active-duty military patients undergoing pectoralis major tendon repair between 2008 and 2013 were identified from the Military Health System using the Management Analysis and Reporting Tool (M2). Demographic characteristics, injury characteristics, and trends in preoperative and postoperative self-reported pain scale (0 to 10) and strength were extracted. The ability to return to the full preoperative level of function and rates of rerupture and reoperation were the primary outcome measures. Univariate analysis followed by multivariate analysis identified significant variables. Results: A total of 257 patients with pectoralis major tendon repair were identified with a mean follow-up (and standard deviation) of 47.8 ± 17 months (range, 24 to 90 months). At the time of the latest follow-up, 242 patients (94%) were able to return to the full preoperative level of military function. Fifteen patients (5.8%) were unable to return to duty because of persistent upper-extremity disability. A total of 15 reruptures occurred in 14 patients (5.4%). Increasing body mass index and active psychiatric conditions were significant predictors of inability to return to function (odds ratio, 1.56 [p = 0.0001] for increasing body mass index; and odds ratio, 6.59 [p = 0.00165] for active psychiatric conditions) and total failure (odds ratio, 1.26 [p = 0.0012] for increasing body mass index; and odds ratio, 2.73 [p = 0.0486] for active psychiatric conditions). Conclusions: We demonstrate that 94% of patients were able to return to the full preoperative level of function within active military duty following surgical repair of pectoralis major tendon rupture and 5.4% of patients experienced rerupture after primary repair. Increasing body mass index and active psychiatric diagnoses are significant risk factors for an inability to return to function and postoperative failures. Level of Evidence: Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
背景:在过去的30年里,胸大肌肌腱断裂在年轻、活跃的个体中越来越常见;然而,目前缺乏报道的结果数据。我们调查了胸大肌肌腱手术修复后恢复到完全术前水平的能力、并发症、再手术率和失败的危险因素。方法:使用管理分析和报告工具(M2)对2008年至2013年期间接受胸大肌肌腱修复的所有美国现役军人患者进行鉴定。提取人口学特征、损伤特征以及术前和术后自我报告疼痛量表(0 - 10)和强度的趋势。恢复到完全术前功能水平的能力、再破裂率和再手术率是主要的观察指标。单因素分析和多因素分析确定了显著变量。结果:257例胸大肌肌腱修复患者,平均随访时间(标准差)为47.8±17个月(范围24 ~ 90个月)。在最近一次随访时,242例患者(94%)能够完全恢复术前的军事功能水平。15例患者(5.8%)由于持续性上肢残疾而无法返回工作岗位。14例(5.4%)复发15次。体重指数增加和活跃的精神状况是无法恢复功能的重要预测因素(体重指数增加的优势比为1.56 [p = 0.0001];积极精神状态的优势比为6.59 [p = 0.00165],而体重指数增加的优势比为1.26 [p = 0.0012];积极精神状态的优势比为2.73 [p = 0.0486]。结论:我们证明,在现役军人中,94%的患者在手术修复胸大肌肌腱断裂后能够恢复到完全的术前功能水平,5.4%的患者在初次修复后复发。增加体重指数和积极的精神病学诊断是无法恢复功能和术后失败的重要危险因素。证据等级:治疗性IV级。完整的证据等级描述见作者指南。
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引用次数: 29
Repeat Two-Stage Exchange Arthroplasty for Periprosthetic Knee Infection Is Dependent on Host Grade 重复两期置换膝关节置换术治疗假体周围膝关节感染取决于宿主等级
Pub Date : 2017-01-04 DOI: 10.2106/JBJS.16.00075
K. Fehring, M. Abdel, M. Ollivier, T. Mabry, A. Hanssen
Background: Two-stage exchange arthroplasty after a previous, failed 2-stage exchange procedure is fraught with difficulties, and there are no clear guidelines for treatment or prognosis given the heterogeneous group of patients in whom this procedure has been performed. The Musculoskeletal Infection Society (MSIS) staging system was developed in an attempt to stratify patients according to infection type, host status, and local soft-tissue status. The purpose of this study was to report the results of 2-stage exchange arthroplasty following a previous, failed 2-stage exchange protocol for periprosthetic knee infection as well as to identify risk factors for failure. Methods: We retrospectively identified 45 patients who had undergone 2 or more 2-stage exchange arthroplasties for periprosthetic knee infection from 2000 to 2013. Patients were stratified according to the MSIS system, and risk factors for failure were analyzed. The minimum follow-up was 2 years (mean, 6 years; range, 24 to 132 months). Results: At the time of follow-up, twenty-two (49%) of the patients had undergone another revision due to infection and 28 (62%) had undergone another revision for any reason. The infection recurred in 6 (75%) of 8 substantially immunocompromised hosts (MSIS type C) and in 3 (30%) of 10 uncompromised hosts (type A) following the second 2-stage exchange arthroplasty (p = 0.06). The infection recurred in 4 (80%) of 5 patients with compromise of the extremity (MSIS type 3) and 3 (33%) of 9 patients with an uncompromised extremity (type 1) (p = 0.27). Both extremely compromised hosts with an extremely compromised extremity (type C3) had recurrence of the infection whereas 3 (30%) of the 10 uncompromised patients with no or less compromise of the extremity (type A1 or A2) did. Five patients in the failure group underwent a third 2-stage exchange arthroplasty following reinfection, and 3 of them were infection-free at the time of the latest follow-up. Conclusions: Uncompromised hosts (MSIS type A) with an acceptable wound (MSIS type 1 or 2) had a 70% rate of success (7 of 10) after a repeat 2-stage exchange arthroplasty, whereas type-B2 hosts had a 50% success rate (10 of 20). The repeat 2-stage exchange procedure failed in both type-C3 hosts; thus, alternative salvage procedures should be considered for such patients. Level of Evidence: Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
背景:在先前失败的两期置换手术后进行两期置换关节充满了困难,考虑到接受该手术的异质患者群体,没有明确的治疗或预后指南。肌肉骨骼感染学会(MSIS)分期系统的建立是为了根据感染类型、宿主状态和局部软组织状态对患者进行分层。本研究的目的是报道两期置换关节置换术治疗假体周围膝关节感染失败后的结果,并确定失败的危险因素。方法:从2000年到2013年,我们回顾性分析了45例因假体周围膝关节感染而接受2次或2期以上置换置换手术的患者。根据MSIS系统对患者进行分层,分析失败的危险因素。最小随访时间为2年(平均6年;范围:24至132个月)。结果:随访时,22例(49%)患者因感染再次翻修,28例(62%)患者因任何原因再次翻修。8例免疫功能严重受损的宿主(MSIS C型)中有6例(75%)感染复发,10例未受损的宿主(A型)中有3例(30%)感染复发(p = 0.06)。5例肢体受损(MSIS 3型)患者中有4例(80%)感染复发,9例肢体未受损(1型)患者中有3例(33%)感染复发(p = 0.27)。两名极度受损且四肢极度受损的患者(C3型)均有感染复发,而10名没有或较少四肢受损的未受损患者(A1或A2型)中有3名(30%)有感染复发。失败组中有5例患者在再次感染后进行了第三次2期置换关节置换术,其中3例患者在最近一次随访时无感染。结论:具有可接受伤口(MSIS 1型或2型)的未受损宿主(MSIS A型)在重复2期置换关节成形术后成功率为70%(7 / 10),而b2型宿主的成功率为50%(10 / 20)。重复2阶段交换过程在两个c3型主机中失败;因此,对于此类患者,应考虑其他挽救手术。证据等级:治疗性IV级。完整的证据等级描述见作者指南。
{"title":"Repeat Two-Stage Exchange Arthroplasty for Periprosthetic Knee Infection Is Dependent on Host Grade","authors":"K. Fehring, M. Abdel, M. Ollivier, T. Mabry, A. Hanssen","doi":"10.2106/JBJS.16.00075","DOIUrl":"https://doi.org/10.2106/JBJS.16.00075","url":null,"abstract":"Background: Two-stage exchange arthroplasty after a previous, failed 2-stage exchange procedure is fraught with difficulties, and there are no clear guidelines for treatment or prognosis given the heterogeneous group of patients in whom this procedure has been performed. The Musculoskeletal Infection Society (MSIS) staging system was developed in an attempt to stratify patients according to infection type, host status, and local soft-tissue status. The purpose of this study was to report the results of 2-stage exchange arthroplasty following a previous, failed 2-stage exchange protocol for periprosthetic knee infection as well as to identify risk factors for failure. Methods: We retrospectively identified 45 patients who had undergone 2 or more 2-stage exchange arthroplasties for periprosthetic knee infection from 2000 to 2013. Patients were stratified according to the MSIS system, and risk factors for failure were analyzed. The minimum follow-up was 2 years (mean, 6 years; range, 24 to 132 months). Results: At the time of follow-up, twenty-two (49%) of the patients had undergone another revision due to infection and 28 (62%) had undergone another revision for any reason. The infection recurred in 6 (75%) of 8 substantially immunocompromised hosts (MSIS type C) and in 3 (30%) of 10 uncompromised hosts (type A) following the second 2-stage exchange arthroplasty (p = 0.06). The infection recurred in 4 (80%) of 5 patients with compromise of the extremity (MSIS type 3) and 3 (33%) of 9 patients with an uncompromised extremity (type 1) (p = 0.27). Both extremely compromised hosts with an extremely compromised extremity (type C3) had recurrence of the infection whereas 3 (30%) of the 10 uncompromised patients with no or less compromise of the extremity (type A1 or A2) did. Five patients in the failure group underwent a third 2-stage exchange arthroplasty following reinfection, and 3 of them were infection-free at the time of the latest follow-up. Conclusions: Uncompromised hosts (MSIS type A) with an acceptable wound (MSIS type 1 or 2) had a 70% rate of success (7 of 10) after a repeat 2-stage exchange arthroplasty, whereas type-B2 hosts had a 50% success rate (10 of 20). The repeat 2-stage exchange procedure failed in both type-C3 hosts; thus, alternative salvage procedures should be considered for such patients. Level of Evidence: Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.","PeriodicalId":22579,"journal":{"name":"The Journal of Bone and Joint Surgery","volume":"29 1","pages":"19–24"},"PeriodicalIF":0.0,"publicationDate":"2017-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80074480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 69
A Comparison of Matched and Unmatched Orthopaedic Surgery Residency Applicants from 2006 to 2014: Data from the National Resident Matching Program 2006年至2014年匹配与不匹配骨科住院医师申请人的比较:来自国家住院医师匹配计划的数据
Pub Date : 2017-01-04 DOI: 10.2106/JBJS.16.00293
J. Schrock, M. Kraeutler, M. Dayton, E. McCarty
Background: The Association of American Medical Colleges publishes residency match data and reports through the National Resident Matching Program (NRMP) every year. The purpose of this study was to analyze trends in orthopaedic surgery residency matching data and characteristics of successful applicants to counsel medical students with regard to their chances of matching. Methods: The annual reports of the NRMP were searched annually from 2006 to 2014 to determine the number of orthopaedic surgery residency positions available, the number of applicants, and the match rate among applicants. Comparisons were performed between matched applicants and unmatched applicants with regard to the number of contiguous ranks and distinct specialties, United States Medical Licensing Examination (USMLE) scores, number of research experiences and research products (abstracts, presentations, posters, publications), and proportion of Alpha Omega Alpha (AOA) Honor Medical Society members and students at a top-40, National Institutes of Health (NIH)-funded medical school. Results: The number of orthopaedic surgery positions available and number of applicants increased at a mean rate of 9 positions and 65 applicants per year (p = 0.11). The mean number of contiguous ranks for U.S. senior medical students was 11.5 for those who matched and 5.5 for those who did not match (p < 0.0001). The USMLE scores for applicants who matched were significantly greater than for those who did not match in each category: Step-1 scores for U.S. seniors (p < 0.001) and independent applicants (p = 0.039), and Step-2 scores for U.S. seniors (p < 0.01) and independent applicants (p = 0.026). The mean number of research products was significantly greater for matched U.S. seniors compared with unmatched U.S. seniors (p = 0.035). A significantly higher proportion of matched U.S. seniors compared with unmatched U.S. seniors were AOA members and students at a top-40, NIH-funded medical school (both p < 0.0001). Conclusions: Successful applicants in the Match for orthopaedic surgery residency have higher USMLE Step-1 and 2 scores, number of research experiences and research products, and contiguous ranks. A higher proportion of successful applicants are AOA members and students at a top-40, NIH-funded medical school.
背景:美国医学院协会每年通过国家住院医师匹配计划(NRMP)发布住院医师匹配数据和报告。本研究的目的是分析骨科住院医师匹配数据的趋势和成功申请者的特征,以咨询医学生他们的匹配机会。方法:检索2006 - 2014年NRMP年度报告,统计骨科外科住院医师职位的空缺数量、申请人数和申请匹配率。比较匹配的申请人和未匹配的申请人之间的连续级别和不同专业的数量,美国医学执照考试(USMLE)分数,研究经验和研究产品(摘要,演讲,海报,出版物)的数量,以及Alpha Omega Alpha (AOA)荣誉医学会成员和美国国立卫生研究院(NIH)资助的前40名医学院学生的比例。结果:骨科职位空缺数量和申请人数平均每年增加9个,申请人数平均每年增加65人(p = 0.11)。美国医学院高年级学生的平均连续排名为,匹配者为11.5,不匹配者为5.5 (p < 0.0001)。在每个类别中,匹配的申请人的USMLE分数显著高于不匹配的申请人:美国高年级学生的第一步分数(p < 0.001)和独立申请人(p = 0.039),美国高年级学生的第二步分数(p < 0.01)和独立申请人(p = 0.026)。与未匹配的美国老年人相比,匹配的美国老年人的平均研究产品数量显著增加(p = 0.035)。与未匹配的美国高年级学生相比,匹配的美国高年级学生中AOA成员和美国国立卫生研究院资助的排名前40的医学院学生的比例明显更高(p < 0.0001)。结论:骨科住院医师匹配成功申请者USMLE step1和step2得分较高,研究经历和研究产品数量较多,排名相邻。较高比例的成功申请者是美国医学协会会员和美国国立卫生研究院资助的排名前40的医学院的学生。
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引用次数: 68
Patient-Reported Outcomes of Periacetabular Osteotomy from the Prospective ANCHOR Cohort Study 前瞻性ANCHOR队列研究中髋臼周围截骨术患者报告的结果
Pub Date : 2017-01-04 DOI: 10.2106/JBJS.15.00798
J. Clohisy, J. Ackerman, Geneva R. Baca, J. Baty, P. Beaulé, Young-Jo Kim, M. Millis, D. Podeszwa, P. Schoenecker, R. Sierra, Ernest L Sink, D. Sucato, R. Trousdale, I. Zaltz
Background: Current literature describing the periacetabular osteotomy (PAO) is mostly limited to retrospective case series. Larger, prospective cohort studies are needed to provide better clinical evidence regarding this procedure. The goals of the current study were to (1) report minimum 2-year patient-reported outcomes (pain, hip function, activity, overall health, and quality of life), (2) investigate preoperative clinical and disease characteristics as predictors of clinical outcomes, and (3) report the rate of early failures and reoperations in patients undergoing contemporary PAO surgery. Methods: A large, prospective, multicenter cohort of PAO procedures was established, and outcomes at a minimum of 2 years were analyzed. A total of 391 hips were included for analysis (79% of the patients were female, and the average patient age was 25.4 years). Patient-reported outcomes, conversion to total hip replacement, reoperations, and major complications were documented. Variables with a p value of ⩽0.10 in the univariate linear regressions were included in the multivariate linear regression. The backward stepwise selection method was used to determine the final risk factors of clinical outcomes. Results: Clinical outcome analysis demonstrated major clinically important improvements in pain, function, quality of life, overall health, and activity level. Increasing age and a body mass index status of overweight or obese were predictive of improved results for certain outcome metrics. Male sex and mild acetabular dysplasia were predictive of lesser improvements in certain outcome measures. Three (0.8%) of the hips underwent early conversion to total hip arthroplasty, 12 (3%) required reoperation, and 26 (7%) experienced a major complication. Conclusions: This large, prospective cohort study demonstrated the clinical success of contemporary PAO surgery for the treatment of symptomatic acetabular dysplasia. Patient and disease characteristics demonstrated predictive value that should be considered in surgical decision-making. Level of Evidence: Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
背景:目前描述髋臼周围截骨术(PAO)的文献大多局限于回顾性病例系列。需要更大规模的前瞻性队列研究来为该手术提供更好的临床证据。本研究的目的是(1)报告至少2年患者报告的结果(疼痛、髋关节功能、活动、整体健康和生活质量),(2)调查术前临床和疾病特征作为临床结果的预测因素,(3)报告接受当代PAO手术患者的早期失败率和再手术率。方法:建立了一个大型的、前瞻性的、多中心的PAO队列,并对至少2年的结果进行了分析。共纳入391个髋关节进行分析(79%的患者为女性,患者平均年龄为25.4岁)。记录了患者报告的结果、转到全髋关节置换术、再手术和主要并发症。单变量线性回归中p值≥0.10的变量被纳入多元线性回归。采用后向逐步选择法确定最终影响临床结局的危险因素。结果:临床结果分析显示在疼痛、功能、生活质量、整体健康和活动水平方面有重大的临床重要改善。年龄的增加和体重指数状态的超重或肥胖可以预测某些结果指标的改善。在某些结果测量中,男性和轻度髋臼发育不良预示着改善较小。3例(0.8%)髋部接受了早期全髋关节置换术,12例(3%)髋部需要再次手术,26例(7%)髋部出现了主要并发症。结论:这项大型前瞻性队列研究证明了当代PAO手术治疗症状性髋臼发育不良的临床成功。患者和疾病特征显示了在手术决策时应考虑的预测价值。证据等级:治疗性IV级。完整的证据等级描述见作者指南。
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引用次数: 146
Reorientational Proximal Femoral Osteotomies for Arthrogrypotic Hip Contractures 复位股骨近端截骨术治疗髋关节挛缩
Pub Date : 2017-01-04 DOI: 10.2106/JBJS.16.00304
H. V. van Bosse, R. Saldana
Background: Severe hip contractures in arthrogrypsosis are multiplanar, which can preclude or can greatly complicate sitting and ambulation. The reorientational osteotomy at the intertrochanteric level preserves preoperative hip motion but moves it to a more functional domain. We retrospectively compared preoperative and postoperative hip motion and evaluated the ambulatory abilities of patients who underwent the procedure. Methods: Since 2008, 65 patients with arthrogryposis had 119 reorientational proximal femoral osteotomies with a minimum follow-up of 2 years. The mean patient age at the time of the surgical procedure was 48 months. An intertrochanteric wedge osteotomy aligned the femoral shaft with the body axis, leaving the hip joint in its preexisting position. A cannulated hip blade plate was used for fixation. Hip motions were recorded preoperatively, at implant removal, and at the time of the latest follow-up, as was ambulatory ability. Results: Eighty-one hips had a mean flexion contracture of 52° preoperatively, which improved by 35°; 84 hips with a mean preoperative adduction of −20° improved by 42°; 101 hips with a mean preoperative internal rotation of −16° improved by 35° (p < 0.0001 for all). The flexion-extension total arc of motion for the 119 hips improved by 13° (p < 0.0001). Only 11 of 94 hips that preoperatively flexed ≥90° did not do so postoperatively, but none of the patients reported seating difficulties and one of the patients had already regained hip flexion of >90° by a soft-tissue release. At a mean follow-up of 40 months, 36 patients were independently ambulatory and 20 patients were walker-dependent. Conclusions: Children with arthrogryposis often have the potential for ambulation if the limb positioning can be optimized. The reorientational hip osteotomy corrects the hip contractures by altering the range of motion but not the total arc of motion. Level of Evidence: Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
背景:关节挛缩症的严重髋关节挛缩是多平面的,这可能妨碍或使坐姿和活动变得非常复杂。股骨粗隆间水平的再定向截骨术保留了术前髋关节的活动,但将其移至功能更强的区域。我们回顾性地比较了术前和术后的髋关节运动,并评估了接受手术的患者的行走能力。方法:自2008年以来,65例关节挛缩患者行119例股骨近端再定向截骨术,随访至少2年。手术时患者的平均年龄为48个月。股骨粗隆间楔形截骨术使股骨轴与体轴对齐,使髋关节保持原有位置。采用空心髋关节钢板固定。记录术前、取出植入物时和最近一次随访时的髋关节运动,以及活动能力。结果:81例髋关节术前平均屈曲挛缩52°,术后平均屈曲挛缩35°;84髋,术前平均内收- 20°,改善42°;术前平均内旋为- 16°的101髋改善了35°(p < 0.0001)。119髋的屈伸总运动弧度提高了13°(p < 0.0001)。94例术前屈曲≥90°的髋关节中,只有11例术后没有出现屈曲,但没有患者报告有坐位困难,其中1例患者通过软组织松解已恢复了90°的髋关节屈曲。在平均40个月的随访中,36例患者独立行走,20例患者依赖助行器。结论:关节挛缩症患儿若能优化肢体定位,往往有活动的潜力。定向髋关节截骨术通过改变髋关节的活动范围来矫正髋关节挛缩,但不能改变髋关节的总活动弧度。证据等级:治疗性IV级。完整的证据等级描述见作者指南。
{"title":"Reorientational Proximal Femoral Osteotomies for Arthrogrypotic Hip Contractures","authors":"H. V. van Bosse, R. Saldana","doi":"10.2106/JBJS.16.00304","DOIUrl":"https://doi.org/10.2106/JBJS.16.00304","url":null,"abstract":"Background: Severe hip contractures in arthrogrypsosis are multiplanar, which can preclude or can greatly complicate sitting and ambulation. The reorientational osteotomy at the intertrochanteric level preserves preoperative hip motion but moves it to a more functional domain. We retrospectively compared preoperative and postoperative hip motion and evaluated the ambulatory abilities of patients who underwent the procedure. Methods: Since 2008, 65 patients with arthrogryposis had 119 reorientational proximal femoral osteotomies with a minimum follow-up of 2 years. The mean patient age at the time of the surgical procedure was 48 months. An intertrochanteric wedge osteotomy aligned the femoral shaft with the body axis, leaving the hip joint in its preexisting position. A cannulated hip blade plate was used for fixation. Hip motions were recorded preoperatively, at implant removal, and at the time of the latest follow-up, as was ambulatory ability. Results: Eighty-one hips had a mean flexion contracture of 52° preoperatively, which improved by 35°; 84 hips with a mean preoperative adduction of −20° improved by 42°; 101 hips with a mean preoperative internal rotation of −16° improved by 35° (p < 0.0001 for all). The flexion-extension total arc of motion for the 119 hips improved by 13° (p < 0.0001). Only 11 of 94 hips that preoperatively flexed ≥90° did not do so postoperatively, but none of the patients reported seating difficulties and one of the patients had already regained hip flexion of >90° by a soft-tissue release. At a mean follow-up of 40 months, 36 patients were independently ambulatory and 20 patients were walker-dependent. Conclusions: Children with arthrogryposis often have the potential for ambulation if the limb positioning can be optimized. The reorientational hip osteotomy corrects the hip contractures by altering the range of motion but not the total arc of motion. Level of Evidence: Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.","PeriodicalId":22579,"journal":{"name":"The Journal of Bone and Joint Surgery","volume":"44 1","pages":"55–64"},"PeriodicalIF":0.0,"publicationDate":"2017-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79956805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
Preoperative Opioid Use Is Associated with Early Revision After Total Knee Arthroplasty: A Study of Male Patients Treated in the Veterans Affairs System 术前阿片类药物使用与全膝关节置换术后早期翻修相关:退伍军人事务系统男性患者的研究
Pub Date : 2017-01-04 DOI: 10.2106/JBJS.16.00167
A. Ben-Ari, H. Chansky, I. Rozet
Background: Opioid use is endemic in the U.S. and is associated with morbidity and mortality. The impact of long-term opioid use on joint-replacement outcomes remains unknown. We tested the hypothesis that use of opioids is associated with adverse outcomes after total knee arthroplasty (TKA). Methods: We performed a retrospective analysis of patients who had had TKA within the U.S. Veterans Affairs (VA) system over a 6-year period and had been followed for 1 year postoperatively. The length of time for which an opioid had been prescribed and the morphine equivalent dose were calculated for each patient. Patients for whom opioids had been prescribed for >3 months in the year prior to the TKA were assigned to the long-term opioid group. A natural language processing-based machine-learning classifier was developed to classify revisions due to infectious and non-infectious causes on the basis of the postoperative note. Survival curves for the time to knee revision or manipulation were used to compare the long-term opioid group with the patients who did not take opioids long-term. Hazard and odds ratios for knee revision and manipulation were obtained as well. Results: Of 32,636 patients (94.4% male; mean age [and standard deviation], 64.45 ± 9.41 years) who underwent TKA, 12,772 (39.1%) were in the long-term opioid group and 734 (2.2%) had a revision within a year after the TKA. Chronic kidney disease, diabetes, and long-term opioid use were associated with revision within 1 year—with odds ratios (95% confidence intervals [CIs]) of 1.76 (1.37 to 2.22), 1.11 (0.93 to 1.31), and 1.40 (1.19 to 1.64), respectively—and were also the leading factors associated with a revision at any time after the index TKA—with odds ratios (95% CIs) of 1.61 (1.34 to 1.92), 1.21 (1.08 to 1.36), and 1.28 (1.15 to 1.43), respectively. Long-term opioid use had a hazard ratio of 1.19 (95% CI = 1.10 to 0.24) in the analysis of its relationship with knee revision, but the hazard was not significant in the analysis of its association with knee manipulation. The accuracy of the text classifier was 0.94, with the area under the receiver operating characteristic curve being 0.99. There was no association between long-term use of opioids and the specific cause for knee revision. Conclusions: Long-term opioid use prior to TKA was associated with an increased risk of knee revision during the first year after TKA among predominantly male patients treated in the VA system. Level of Evidence: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
背景:阿片类药物的使用在美国是地方性的,并与发病率和死亡率相关。长期使用阿片类药物对关节置换术结果的影响尚不清楚。我们检验了阿片类药物的使用与全膝关节置换术(TKA)后不良后果相关的假设。方法:我们对美国退伍军人事务(VA)系统内6年以上的TKA患者进行了回顾性分析,并在术后随访1年。计算每位患者服用阿片类药物的时间长度和吗啡当量剂量。在TKA前一年,阿片类药物处方为100 - 30个月的患者被分配到长期阿片类药物组。开发了一种基于自然语言处理的机器学习分类器,根据术后笔记对传染性和非传染性原因的修订进行分类。使用到膝关节翻修或操作时间的生存曲线来比较长期服用阿片类药物组与未长期服用阿片类药物组的患者。还获得了膝关节翻修和操作的风险比和优势比。结果:32,636例患者中,男性94.4%;接受TKA的平均年龄[及标准差],64.45±9.41岁],长期阿片类药物组12,772例(39.1%),TKA后一年内进行了修改的734例(2.2%)。慢性肾脏疾病、糖尿病和长期阿片类药物使用与1年内的修订相关,比值比(95%置信区间[ci])分别为1.76(1.37 ~ 2.22)、1.11(0.93 ~ 1.31)和1.40(1.19 ~ 1.64),也是tka指数后任何时间进行修订相关的主要因素,比值比(95% ci)分别为1.61(1.34 ~ 1.92)、1.21(1.08 ~ 1.36)和1.28(1.15 ~ 1.43)。在分析长期阿片类药物使用与膝关节翻修的关系时,其风险比为1.19 (95% CI = 1.10 ~ 0.24),但在分析长期阿片类药物使用与膝关节操作的关系时,其风险比不显著。文本分类器的准确率为0.94,接收者工作特征曲线下面积为0.99。长期使用阿片类药物与膝关节翻修的具体原因之间没有关联。结论:在VA系统治疗的主要男性患者中,TKA前长期使用阿片类药物与TKA后第一年膝关节翻修的风险增加有关。证据等级:治疗性III级。有关证据水平的完整描述,请参见作者说明。
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引用次数: 150
A Dedicated Orthopaedic Trauma Operating Room Improves Efficiency at a Pediatric Center 专门的骨科创伤手术室提高了儿科中心的效率
Pub Date : 2017-01-04 DOI: 10.2106/JBJS.16.00640
C. Brusalis, Apurva S. Shah, X. Luan, Meaghan Lutts, W. Sankar
Background: Dedicated orthopaedic trauma operating rooms have improved operating room efficiency, physician schedules, and patient outcomes in adult populations. The purpose of this study was to determine if a dedicated orthopaedic trauma operating room was associated with improved patient flow and cost savings at a level-I pediatric trauma center. Methods: A retrospective analysis was performed for two 3-year intervals before and after implementation of a weekday, unbooked operating room reserved for orthopaedic trauma cases. Index procedures for 5 common fractures were investigated, including supracondylar humeral fractures, both bone forearm fractures, lateral condylar fractures, tibial fractures, and femoral fractures. To provide a control group to account for potential extrinsic changes in hospital efficiency, laparoscopic appendectomies were also analyzed. For each procedure, efficiency parameters and surgical complications, defined as unplanned reoperations, were compared between time periods. The mean cost reduction per patient was calculated on the basis of the mean daily cost of an inpatient hospital bed. Results: Of 1,469 orthopaedic procedures analyzed, 719 cases occurred before the implementation of the dedicated orthopaedic trauma operating room, and 750 cases were performed after the implementation. The frequency of after-hours procedures (5 P.M. to 7 A.M.) was reduced by 48% (p < 0.001). The mean wait time for the operating room decreased among supracondylar humeral fractures, lateral condylar fractures, and tibial fractures, whereas no significant decrease (p = 0.302) occurred among 2,076 laparoscopic appendectomy cases. The mean duration of the surgical procedure and the mean time in the operating room were not significantly affected. Across all orthopaedic procedures, the mean duration of inpatient hospitalization decreased by 5.6 hours (p < 0.001), but no significant difference occurred among appendectomies. Decreased length of stay resulted in a mean cost reduction of $1,251 per patient. Supracondylar humeral fracture cases performed after implementation of the dedicated orthopaedic trauma operating room had fewer surgical complications (p = 0.018). No difference in complication rate was detected among the other orthopaedic procedures. Conclusions: A dedicated orthopaedic trauma operating room in a pediatric trauma center was associated with fewer after-hours procedures, decreased wait time to the surgical procedure, reduced length of hospitalization, and decreased cost.
背景:专门的骨科创伤手术室提高了手术室效率、医生时间表和成人患者的预后。本研究的目的是确定一个专门的骨科创伤手术室是否与改善一级儿科创伤中心的病人流量和节省成本有关。方法:回顾性分析骨科外伤患者在实施工作日无预约手术室前后2个3年的时间间隔。研究了5种常见骨折的治疗方法,包括肱骨髁上骨折、前臂双侧骨折、外侧髁骨折、胫骨骨折和股骨骨折。为了提供一个对照组来解释医院效率的潜在外在变化,腹腔镜阑尾切除术也进行了分析。对于每个手术,效率参数和手术并发症(定义为计划外再手术)在不同时间段之间进行比较。每位患者的平均成本降低是根据住院病床的平均每日成本计算的。结果:在分析的1469例骨科手术中,719例发生在骨科创伤专用手术室实施前,750例发生在骨科创伤专用手术室实施后。下班后手术(下午5点至早上7点)的频率减少了48% (p < 0.001)。肱骨髁上骨折、外侧髁骨折和胫骨骨折的平均手术室等待时间减少,而2076例腹腔镜阑尾切除术患者的平均手术室等待时间没有显著减少(p = 0.302)。手术的平均持续时间和在手术室的平均时间没有明显的影响。在所有骨科手术中,平均住院时间减少了5.6小时(p < 0.001),但在阑尾切除术中没有显著差异。住院时间的缩短使每位患者的平均费用减少了1,251美元。肱骨髁上骨折在骨科创伤专用手术室实施后手术并发症较少(p = 0.018)。其他骨科手术的并发症发生率无差异。结论:在儿科创伤中心设立专门的骨科创伤手术室,可以减少手术时间,减少手术等待时间,缩短住院时间,降低费用。
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引用次数: 25
ORIF or Arthroplasty for Displaced Femoral Neck Fractures in Patients Younger Than 65 Years Old: An Economic Decision Analysis 年龄小于65岁的移位性股骨颈骨折患者采用ORIF或关节置换术:经济决策分析
Pub Date : 2017-01-04 DOI: 10.2106/JBJS.16.00406
E. Swart, Paulvalery Roulette, Daniel Leas, K. Bozic, M. Karunakar
Background: The decision between open reduction and internal fixation (ORIF) and arthroplasty for a displaced femoral neck fracture in a patient ⩽65 years old can be challenging. Both options have potential drawbacks; if a fracture treated with ORIF fails to heal it may require a revision operation, whereas a relatively young patient who undergoes arthroplasty may need revision within his/her lifetime. The purpose of this study was to employ decision analysis modeling techniques to generate evidence-based treatment recommendations in this clinical scenario. Methods: A Markov decision analytic model was created to simulate outcomes after ORIF, total hip arthroplasty (THA), or hemiarthroplasty in patients who had sustained a displaced femoral neck fracture between the ages of 40 and 65 years. The variables in the model were populated with values from studies with high-level evidence and from national registry data reported in the literature. The model was used to estimate the threshold age above which THA would be the superior strategy. Results were tested using sensitivity analysis and probabilistic statistical analysis. Results: THA was found to be a cost-effective option for a displaced femoral neck fracture in an otherwise healthy patient who is >54 years old, a patient with mild comorbidity who is >47 years old, and a patient with multiple comorbidities who is >44 years old. The average clinical outcomes of THA and ORIF were similar for patients 40 to 65 years old, although ORIF had a wider variability in outcomes based on the success or failure of the initial fixation. For all ages and cases, hemiarthroplasty was associated with worse outcomes and higher costs. Conclusions: Compared with ORIF, primary THA can be a cost-effective treatment for displaced femoral neck fractures in patients 45 to 65 years of age, with the age cutoff favoring THA decreasing as the medical comorbidity and risk of ORIF fixation failure increase. Hemiarthroplasty has worse outcomes at higher costs and is not recommended in this age group. Level of Evidence: Economic and decision analysis Level III. See Instructions for Authors for a complete description of levels of evidence.
背景:对于年龄≥65岁的移位性股骨颈骨折患者,在切开复位内固定(ORIF)和关节置换术之间的选择是具有挑战性的。这两种选择都有潜在的缺点;如果经ORIF治疗的骨折不能愈合,则可能需要进行翻修手术,而相对年轻的接受关节置换术的患者可能需要在其一生中进行翻修。本研究的目的是采用决策分析建模技术,在这种临床情况下生成循证治疗建议。方法:建立马尔科夫决策分析模型,模拟40 ~ 65岁股骨颈移位骨折患者接受ORIF、全髋关节置换术(THA)或半髋关节置换术后的预后。模型中的变量由具有高水平证据的研究和文献中报告的国家登记数据的值填充。该模型用于估计阈值年龄,超过该阈值年龄,THA将是优越的策略。采用敏感性分析和概率统计分析对结果进行检验。结果:对于54岁以上的健康患者、47岁以上的轻度合并症患者和44岁以上的多重合并症患者,THA是治疗移位性股骨颈骨折的一种经济有效的选择。对于40 - 65岁的患者,THA和ORIF的平均临床结果相似,尽管ORIF根据初始固定的成功或失败在结果上有更大的可变性。对于所有年龄和病例,半关节置换术与较差的结果和较高的费用相关。结论:与ORIF相比,对于45 - 65岁的移位性股骨颈骨折患者,初级THA是一种经济有效的治疗方法,随着医疗合并症和ORIF固定失败风险的增加,适合THA的年龄限制逐渐降低。半关节置换术的效果较差,费用较高,不建议在这个年龄组进行。证据等级:经济和决策分析三级。有关证据水平的完整描述,请参见作者说明。
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引用次数: 47
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The Journal of Bone and Joint Surgery
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