Shruti Gupta, A. Narwal, M. Kamboj, A. Devi, A. Hooda
ABSTRACT Objectives The purpose of present study was to investigate and correlate the histological findings in central giant cell granuloma and peripheral giant cell granuloma of jaws with clinical and radiographic interpretations of the lesion. Material and Methods In present study, data from 14 cases of central giant cell granuloma (CGCG) and 9 cases of peripheral giant cell granuloma (PGCG) were analysed, focusing on demographic, clinical and radiographic features. For each patient, microscopic slides were assessed in terms of histologic features of giant cells i.e. number of giant cells, mean number of nuclei/giant cell, pattern of distribution, size and relative size index of giant cells, percentage fractional surface area (FSA) occupied by giant cells and stromal characteristics. Data collected was subjected to statistical analysis. Fisher-exact test, Pearson’s correlation coefficient, one-way ANOVA test and Student’s t-test were used for analysis. Results No significant difference was found between PGCG and CGCG in relation to all the traits that were evaluated. It was observed that mean number of giant cells and mean FSA was more in aggressive CGCG as compared to non-aggressive CGCG. Conclusions Further studies on large sample size are required to confirm the relationship between histomorphometric features of giant cells and behaviour of giant cell granulomas of jaws.
{"title":"Giant Cell Granulomas of Jaws: a Clinicopathologic Study","authors":"Shruti Gupta, A. Narwal, M. Kamboj, A. Devi, A. Hooda","doi":"10.5037/jomr.2019.10205","DOIUrl":"https://doi.org/10.5037/jomr.2019.10205","url":null,"abstract":"ABSTRACT Objectives The purpose of present study was to investigate and correlate the histological findings in central giant cell granuloma and peripheral giant cell granuloma of jaws with clinical and radiographic interpretations of the lesion. Material and Methods In present study, data from 14 cases of central giant cell granuloma (CGCG) and 9 cases of peripheral giant cell granuloma (PGCG) were analysed, focusing on demographic, clinical and radiographic features. For each patient, microscopic slides were assessed in terms of histologic features of giant cells i.e. number of giant cells, mean number of nuclei/giant cell, pattern of distribution, size and relative size index of giant cells, percentage fractional surface area (FSA) occupied by giant cells and stromal characteristics. Data collected was subjected to statistical analysis. Fisher-exact test, Pearson’s correlation coefficient, one-way ANOVA test and Student’s t-test were used for analysis. Results No significant difference was found between PGCG and CGCG in relation to all the traits that were evaluated. It was observed that mean number of giant cells and mean FSA was more in aggressive CGCG as compared to non-aggressive CGCG. Conclusions Further studies on large sample size are required to confirm the relationship between histomorphometric features of giant cells and behaviour of giant cell granulomas of jaws.","PeriodicalId":230885,"journal":{"name":"Journal of Oral & Maxillofacial Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123705883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Modabber, F. Peters, Anna Brokmeier, E. Goloborodko, A. Ghassemi, B. Lethaus, F. Hölzle, S. C. Möhlhenrich
ABSTRACT Objectives In this study is investigated if bundling of two scanners leads to better accuracy in recording faces than a standard face-scanning device. Material and Methods In a group of 28 volunteers, two test specimens were attached to their faces: one on their forehead and one turned 90° on their cheek. Each volunteer was scanned by FaceScan3D® and two bundled Artec EVA® scanners. The scans were aligned to a three-dimensional model of the test specimen, and the mean error was recorded. Length, width and angles between the test specimen’s planes were compared. Results The mean deviation is significantly lower for the cheek test specimen in alignment (P < 0.001), length and width (P < 0.001) but not for the forehead test specimen in alignment and length and width (P > 0.05) using FaceScan3D®. The aberration from the original angle between two sides of the test specimen is significantly lower measured with Artec EVA® for the angle between the front and the bottom plane of both test specimens (P < 0.01). Besides the angle between the right plane and the bottom plane as well as the top plane of the test specimen mounted to the cheek, the deviation of the angle between the other side planes to each other is significantly lower (P > 0.05) scanned with Artec EVA®. Conclusions Compared to FaceScan3D®, two bundled Artec EVA® scanners provide different accuracies depending on the location of the measured parameters. The accuracy measured for both scanners is inside the range found in the literature.
{"title":"Influence of Connecting Two Standalone Mobile Three-Dimensional Scanners on Accuracy Comparing with a Standard Device in Facial Scanning","authors":"A. Modabber, F. Peters, Anna Brokmeier, E. Goloborodko, A. Ghassemi, B. Lethaus, F. Hölzle, S. C. Möhlhenrich","doi":"10.5037/jomr.2016.7404","DOIUrl":"https://doi.org/10.5037/jomr.2016.7404","url":null,"abstract":"ABSTRACT Objectives In this study is investigated if bundling of two scanners leads to better accuracy in recording faces than a standard face-scanning device. Material and Methods In a group of 28 volunteers, two test specimens were attached to their faces: one on their forehead and one turned 90° on their cheek. Each volunteer was scanned by FaceScan3D® and two bundled Artec EVA® scanners. The scans were aligned to a three-dimensional model of the test specimen, and the mean error was recorded. Length, width and angles between the test specimen’s planes were compared. Results The mean deviation is significantly lower for the cheek test specimen in alignment (P < 0.001), length and width (P < 0.001) but not for the forehead test specimen in alignment and length and width (P > 0.05) using FaceScan3D®. The aberration from the original angle between two sides of the test specimen is significantly lower measured with Artec EVA® for the angle between the front and the bottom plane of both test specimens (P < 0.01). Besides the angle between the right plane and the bottom plane as well as the top plane of the test specimen mounted to the cheek, the deviation of the angle between the other side planes to each other is significantly lower (P > 0.05) scanned with Artec EVA®. Conclusions Compared to FaceScan3D®, two bundled Artec EVA® scanners provide different accuracies depending on the location of the measured parameters. The accuracy measured for both scanners is inside the range found in the literature.","PeriodicalId":230885,"journal":{"name":"Journal of Oral & Maxillofacial Research","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129550948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ABSTRACT Objectives Osteonecrosis of the jaws is a side effect associated with the use of bisphosphonates. Using histologic analysis, this study aimed to evaluate the influence of microbial colonies in the development of osteonecrosis in the jaws of rats subjected to nitrogenous and non-nitrogenous bisphosphonates, undergoing surgical procedures. Material and Methods Thirty-four rats (Rattus norvegicus, Wistar strain) were allocated randomly into three groups: 12 animals treated with zoledronic acid; 12 animals treated with clodronate; and 10 animals treated with saline. Sixty days after the start of treatment, the animals underwent three extractions of the upper right molars. After 120 days of drug administration, the rats were killed. Histologic analysis was performed on specimens stained with hematoxylin and eosin by the technique of manual counting points using Image-Pro Plus software on images of the right hemimaxilla. Results Osteonecrosis was induced in the test groups. There was no statistically significant association between the presence of microbial colonies and the presence of non-vital bone (Kruskal-Wallis, P > 0.05). Conclusions Use of zoledronic acid was associated with non-vital bone and the results suggested that the presence of microbial colonies does not lead to osteonecrosis.
目的颌骨骨坏死是与使用双磷酸盐相关的副作用。通过组织学分析，本研究旨在评估微生物菌落对接受外科手术的大鼠接受含氮和非含氮双膦酸盐治疗后颌骨骨坏死发展的影响。材料与方法褐家鼠Wistar品系34只，随机分为3组:唑来膦酸组12只;12只动物用氯膦酸钠治疗;另外10只动物接受生理盐水治疗。治疗开始60天后，这些动物进行了三次右上磨牙的拔除。给药120天后，老鼠被杀死。采用Image-Pro Plus软件对右半上颌骨图像采用人工点数法对苏木精和伊红染色标本进行组织学分析。结果各组小鼠均出现骨坏死。微生物菌落的存在与非重要骨的存在之间无统计学意义(Kruskal-Wallis, P < 0.05)。结论使用唑来膦酸与非活骨相关，结果表明微生物菌落的存在不会导致骨坏死。
{"title":"Microscopic Evaluation of the Effect of Oral Microbiota on the Development of Bisphosphonate-Related Osteonecrosis of the Jaws in Rats","authors":"F. Silveira, A. Etges, M. Corrêa, A. Vasconcelos","doi":"10.5037/jomr.2016.7403","DOIUrl":"https://doi.org/10.5037/jomr.2016.7403","url":null,"abstract":"ABSTRACT Objectives Osteonecrosis of the jaws is a side effect associated with the use of bisphosphonates. Using histologic analysis, this study aimed to evaluate the influence of microbial colonies in the development of osteonecrosis in the jaws of rats subjected to nitrogenous and non-nitrogenous bisphosphonates, undergoing surgical procedures. Material and Methods Thirty-four rats (Rattus norvegicus, Wistar strain) were allocated randomly into three groups: 12 animals treated with zoledronic acid; 12 animals treated with clodronate; and 10 animals treated with saline. Sixty days after the start of treatment, the animals underwent three extractions of the upper right molars. After 120 days of drug administration, the rats were killed. Histologic analysis was performed on specimens stained with hematoxylin and eosin by the technique of manual counting points using Image-Pro Plus software on images of the right hemimaxilla. Results Osteonecrosis was induced in the test groups. There was no statistically significant association between the presence of microbial colonies and the presence of non-vital bone (Kruskal-Wallis, P > 0.05). Conclusions Use of zoledronic acid was associated with non-vital bone and the results suggested that the presence of microbial colonies does not lead to osteonecrosis.","PeriodicalId":230885,"journal":{"name":"Journal of Oral & Maxillofacial Research","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127109175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ABSTRACT Objectives The objective of the present systematic review was to test the hypothesis of no difference in transverse skeletal and dental arch expansion and relapse after segmental Le Fort I osteotomy versus surgically assisted rapid maxillary expansion. Material and Methods A MEDLINE (PubMed), Embase and Cochrane library search in combination with a hand-search of relevant journals was conducted by including human studies published in English from January 1, 2000 to June 1, 2016. Results The search provided 130 titles and four studies fulfilled the inclusion criteria. All the included studies were characterized by high risk of bias and meta-analysis was not possible due to considerable variation. Both treatment modalities significantly increase the transverse maxillary skeletal and dental arch width. The transverse dental arch expansion and relapse seems to be substantial higher with tooth-borne surgically assisted rapid maxillary expansion compared to segmental Le Fort I osteotomy. The ratio of dental to skeletal relapse was significantly higher in the posterior maxilla with tooth-borne surgically assisted rapid maxillary expansion. Moreover, a parallel opening without segment tilting was observed after segmental Le Fort I osteotomy. Conclusions Maxillary transverse deficiency in adults can be treated successfully with both treatment modalities, although surgically assisted rapid maxillary expansion seems more effective when large transverse maxillary skeletal and dental arch expansion is required. However, considering the methodological limitations of the included studies, long-term randomized studies assessing transverse skeletal and dental expansion and relapse with the two treatment modalities are needed before definite conclusions can be provided.
摘要目的本系统综述的目的是验证Le Fort I节段截骨术与手术辅助快速上颌扩张术在横向骨骼和牙弓扩张和复发方面无差异的假设。材料与方法通过MEDLINE (PubMed)、Embase和Cochrane图书馆检索，结合手工检索相关期刊，纳入2000年1月1日至2016年6月1日发表的英文人类研究。结果共检索到130篇文献，其中4篇符合纳入标准。所有纳入的研究均具有高偏倚风险，由于差异较大，无法进行meta分析。两种治疗方式均可显著增加上颌横骨和牙弓宽度。与节段性Le Fort I截骨术相比，牙体手术辅助快速上颌扩张术的横向牙弓扩张和复发似乎要高得多。后上颌采用牙源性手术辅助快速扩张的复发率明显高于骨骼复发率。此外，节段Le Fort I截骨术后观察到平行开口无节段倾斜。结论两种治疗方式均可成功治疗成人上颌横向缺损，但当需要进行较大的上颌横向骨骼和牙弓扩张时，手术辅助快速上颌扩张似乎更有效。然而，考虑到纳入研究的方法学局限性，在提供明确的结论之前，需要进行长期随机研究，评估两种治疗方式下的横向骨骼和牙齿扩张和复发。
{"title":"Transverse Expansion and Stability after Segmental Le Fort I Osteotomy versus Surgically Assisted Rapid Maxillary Expansion: a Systematic Review","authors":"T. Starch-Jensen, T. L. Blæhr","doi":"10.5037/jomr.2016.7401","DOIUrl":"https://doi.org/10.5037/jomr.2016.7401","url":null,"abstract":"ABSTRACT Objectives The objective of the present systematic review was to test the hypothesis of no difference in transverse skeletal and dental arch expansion and relapse after segmental Le Fort I osteotomy versus surgically assisted rapid maxillary expansion. Material and Methods A MEDLINE (PubMed), Embase and Cochrane library search in combination with a hand-search of relevant journals was conducted by including human studies published in English from January 1, 2000 to June 1, 2016. Results The search provided 130 titles and four studies fulfilled the inclusion criteria. All the included studies were characterized by high risk of bias and meta-analysis was not possible due to considerable variation. Both treatment modalities significantly increase the transverse maxillary skeletal and dental arch width. The transverse dental arch expansion and relapse seems to be substantial higher with tooth-borne surgically assisted rapid maxillary expansion compared to segmental Le Fort I osteotomy. The ratio of dental to skeletal relapse was significantly higher in the posterior maxilla with tooth-borne surgically assisted rapid maxillary expansion. Moreover, a parallel opening without segment tilting was observed after segmental Le Fort I osteotomy. Conclusions Maxillary transverse deficiency in adults can be treated successfully with both treatment modalities, although surgically assisted rapid maxillary expansion seems more effective when large transverse maxillary skeletal and dental arch expansion is required. However, considering the methodological limitations of the included studies, long-term randomized studies assessing transverse skeletal and dental expansion and relapse with the two treatment modalities are needed before definite conclusions can be provided.","PeriodicalId":230885,"journal":{"name":"Journal of Oral & Maxillofacial Research","volume":"67 5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128684346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Gambarini, L. Piasecki, D. Di Nardo, G. Miccoli, G. Di Giorgio, E. Carneiro, D. Al-Sudani, L. Testarelli
ABSTRACT Objectives The aim of the present study was to investigate the incidence of deformation and fracture of twisted file adaptive nickel-titanium instruments after repeated clinical use and to identify and check whether the three instruments within the small/medium sequence showed similar or different visible signs of metal fatigue. Material and Methods One-hundred twenty twisted file adaptive (TFA) packs were collected after clinically used to prepare three molars and were inspected for deformations and fracture. Results The overall incidence of deformation was 22.2%, which was not evenly distributed within the instruments: 15% for small/medium (SM)1 (n = 18), 38.33% for SM2 (n = 46) and 13.33% for the SM3 instruments (n = 16). The defect rate of SM2 instruments was statistically higher than the other two (P < 0.001). The fracture rate was 0.83% (n = 3), being two SM2 instruments and one SM3. Conclusions It was observed a very low defect rate after clinical use of twisted file adaptive rotary instruments. The untwisting of flutes was significantly more frequent than fracture, which might act as prevention for breakage. The results highlight the fact that clinicians should be aware that instruments within a sequence might be differently subjected to intracanal stress.
{"title":"Incidence of Deformation and Fracture of Twisted File Adaptive Instruments after Repeated Clinical Use","authors":"G. Gambarini, L. Piasecki, D. Di Nardo, G. Miccoli, G. Di Giorgio, E. Carneiro, D. Al-Sudani, L. Testarelli","doi":"10.5037/jomr.2016.7405","DOIUrl":"https://doi.org/10.5037/jomr.2016.7405","url":null,"abstract":"ABSTRACT Objectives The aim of the present study was to investigate the incidence of deformation and fracture of twisted file adaptive nickel-titanium instruments after repeated clinical use and to identify and check whether the three instruments within the small/medium sequence showed similar or different visible signs of metal fatigue. Material and Methods One-hundred twenty twisted file adaptive (TFA) packs were collected after clinically used to prepare three molars and were inspected for deformations and fracture. Results The overall incidence of deformation was 22.2%, which was not evenly distributed within the instruments: 15% for small/medium (SM)1 (n = 18), 38.33% for SM2 (n = 46) and 13.33% for the SM3 instruments (n = 16). The defect rate of SM2 instruments was statistically higher than the other two (P < 0.001). The fracture rate was 0.83% (n = 3), being two SM2 instruments and one SM3. Conclusions It was observed a very low defect rate after clinical use of twisted file adaptive rotary instruments. The untwisting of flutes was significantly more frequent than fracture, which might act as prevention for breakage. The results highlight the fact that clinicians should be aware that instruments within a sequence might be differently subjected to intracanal stress.","PeriodicalId":230885,"journal":{"name":"Journal of Oral & Maxillofacial Research","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121469287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yoko Henmi, Yoshihito Naito, R. Jimbo, Y. Jinno, K. Sekine, K. Hamada
ABSTRACT Objectives The objective of this study is to develop a Ti fibre knit block without sintering, and to evaluate its deformability and new bone formation in vivo. Material and Methods A Ti fibre with a diameter of 150 μm was knitted to fabricate a Ti mesh tube. The mesh tube was compressed in a metal mould to fabricate porous Ti fibre knit blocks with three different porosities of 88%, 69%, and 50%. The elastic modulus and deformability were evaluated using a compression test. The knit block was implanted into bone defects of a rabbit’s hind limb, and new bone formation was evaluated using micro computed tomography (micro-CT) analysis and histological analysis. Results The knit blocks with 88% porosity showed excellent deformability, indicating potential appropriateness for bone defect filling. Although the porosities of the knit block were different, they indicated similar elastic modulus smaller than 1 GPa. The elastic modulus after deformation increased linearly as the applied compression stress increased. The micro-CT analysis indicated that in the block with 50% porosity new bone filled nearly all of the pore volume four weeks after implantation. In contrast, in the block with 88% porosity, new bone filled less than half of the pore volume even 12 weeks after implantation. The histological analysis also indicated new bone formation in the block. Conclusions The titanium fibre knit block with high porosity is potentially appropriate for bone defect filling, indicating good bone ingrowth after porosity reduction with applied compression.
{"title":"Bone Ingrowth to Ti Fibre Knit Block with High Deformability","authors":"Yoko Henmi, Yoshihito Naito, R. Jimbo, Y. Jinno, K. Sekine, K. Hamada","doi":"10.5037/jomr.2016.7402","DOIUrl":"https://doi.org/10.5037/jomr.2016.7402","url":null,"abstract":"ABSTRACT Objectives The objective of this study is to develop a Ti fibre knit block without sintering, and to evaluate its deformability and new bone formation in vivo. Material and Methods A Ti fibre with a diameter of 150 μm was knitted to fabricate a Ti mesh tube. The mesh tube was compressed in a metal mould to fabricate porous Ti fibre knit blocks with three different porosities of 88%, 69%, and 50%. The elastic modulus and deformability were evaluated using a compression test. The knit block was implanted into bone defects of a rabbit’s hind limb, and new bone formation was evaluated using micro computed tomography (micro-CT) analysis and histological analysis. Results The knit blocks with 88% porosity showed excellent deformability, indicating potential appropriateness for bone defect filling. Although the porosities of the knit block were different, they indicated similar elastic modulus smaller than 1 GPa. The elastic modulus after deformation increased linearly as the applied compression stress increased. The micro-CT analysis indicated that in the block with 50% porosity new bone filled nearly all of the pore volume four weeks after implantation. In contrast, in the block with 88% porosity, new bone filled less than half of the pore volume even 12 weeks after implantation. The histological analysis also indicated new bone formation in the block. Conclusions The titanium fibre knit block with high porosity is potentially appropriate for bone defect filling, indicating good bone ingrowth after porosity reduction with applied compression.","PeriodicalId":230885,"journal":{"name":"Journal of Oral & Maxillofacial Research","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124217955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Suárez-López Del Amo, Shan-Huey Yu, Hom-lay Wang
ABSTRACT Objectives The purpose of this paper was to systematically evaluate the effectiveness of non-surgical therapy for the treatment of peri-implant diseases including both, mucositis and peri-implantitis lesions. Material and Methods An electronic search in two different databases was performed including MEDLINE (PubMed) and EMBASE from 2011 to 2016. Human studies reporting non-surgical treatment of peri-implant mucositis and peri-implantitis with more than 10 implants and at least 6 months follow up published in English language were evaluated. A systematic review was performed to evaluate the effectiveness of the different methods of decontamination employed in the included investigations. Risk of bias assessment was elaborated for included investigations. Results Twenty-five articles were identified of which 14 were further evaluated and included in the analysis. Due to significant heterogeneity in between included studies, a meta-analysis could not be performed. Instead, a systematic descriptive review was performed. Included investigations reported the used of different methods for implant decontamination, including self-performed cleaning techniques, and professionally delivered treatment such as laser, photodynamic therapy, supra-/sub-mucosal mechanical debridement, and air-abrasive devices. Follow-up periods ranged from 6 to 60 months. Conclusions Non-surgical treatment for peri-implant mucositis seems to be effective while modest and not-predictable outcomes are expected for peri-implantitis lesions. Limitations include different peri-implant diseases definitions, treatment approaches, as well as different implant designs/surfaces and defect characteristics.
{"title":"Non-Surgical Therapy for Peri-Implant Diseases: a Systematic Review","authors":"F. Suárez-López Del Amo, Shan-Huey Yu, Hom-lay Wang","doi":"10.5037/jomr.2016.7313","DOIUrl":"https://doi.org/10.5037/jomr.2016.7313","url":null,"abstract":"ABSTRACT Objectives The purpose of this paper was to systematically evaluate the effectiveness of non-surgical therapy for the treatment of peri-implant diseases including both, mucositis and peri-implantitis lesions. Material and Methods An electronic search in two different databases was performed including MEDLINE (PubMed) and EMBASE from 2011 to 2016. Human studies reporting non-surgical treatment of peri-implant mucositis and peri-implantitis with more than 10 implants and at least 6 months follow up published in English language were evaluated. A systematic review was performed to evaluate the effectiveness of the different methods of decontamination employed in the included investigations. Risk of bias assessment was elaborated for included investigations. Results Twenty-five articles were identified of which 14 were further evaluated and included in the analysis. Due to significant heterogeneity in between included studies, a meta-analysis could not be performed. Instead, a systematic descriptive review was performed. Included investigations reported the used of different methods for implant decontamination, including self-performed cleaning techniques, and professionally delivered treatment such as laser, photodynamic therapy, supra-/sub-mucosal mechanical debridement, and air-abrasive devices. Follow-up periods ranged from 6 to 60 months. Conclusions Non-surgical treatment for peri-implant mucositis seems to be effective while modest and not-predictable outcomes are expected for peri-implantitis lesions. Limitations include different peri-implant diseases definitions, treatment approaches, as well as different implant designs/surfaces and defect characteristics.","PeriodicalId":230885,"journal":{"name":"Journal of Oral & Maxillofacial Research","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117218667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ABSTRACT Objectives To review the current understanding of the biomarkers and enzymes associated with different forms peri-implant diseases and how their level changes influence the pathogenesis of the inflammatory diseases around dental implants. Material and Methods An electronic search in two different databases was performed including MEDLINE (PubMed) and EMBASE between 1996 to 2016. Human studies analyse peri-implant crevicular fluid (PICF) biomarker and enzyme levels of implants having peri-implant mucositis and peri-implantitis published in English language, were evaluated. A systematic review was performed to assess which biomarkers and enzymes in PICF were used to identify the inflammatory conditions around dental implants. Results Fifty-one articles were identified of which 41 were further evaluated and included in the analysis. Due to significant heterogeneity between included studies, a meta-analysis could not be performed. Instead, a systematic descriptive review was performed. Conclusions Biomarkers and enzymes in peri-implant crevicular fluid have shown promising results in differentiating from peri-implant disease condition to health. However, due to inconsistent results and acquiring much evidence from cross-sectional studies, additional evidence supported by randomized-controlled trials is needed to validate the links reported.
{"title":"Peri-Implant Crevicular Fluid Analysis, Enzymes and Biomarkers: a Systemetic Review","authors":"E. Dursun, T. Tözüm","doi":"10.5037/jomr.2016.7309","DOIUrl":"https://doi.org/10.5037/jomr.2016.7309","url":null,"abstract":"ABSTRACT Objectives To review the current understanding of the biomarkers and enzymes associated with different forms peri-implant diseases and how their level changes influence the pathogenesis of the inflammatory diseases around dental implants. Material and Methods An electronic search in two different databases was performed including MEDLINE (PubMed) and EMBASE between 1996 to 2016. Human studies analyse peri-implant crevicular fluid (PICF) biomarker and enzyme levels of implants having peri-implant mucositis and peri-implantitis published in English language, were evaluated. A systematic review was performed to assess which biomarkers and enzymes in PICF were used to identify the inflammatory conditions around dental implants. Results Fifty-one articles were identified of which 41 were further evaluated and included in the analysis. Due to significant heterogeneity between included studies, a meta-analysis could not be performed. Instead, a systematic descriptive review was performed. Conclusions Biomarkers and enzymes in peri-implant crevicular fluid have shown promising results in differentiating from peri-implant disease condition to health. However, due to inconsistent results and acquiring much evidence from cross-sectional studies, additional evidence supported by randomized-controlled trials is needed to validate the links reported.","PeriodicalId":230885,"journal":{"name":"Journal of Oral & Maxillofacial Research","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124114636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Suárez-López Del Amo, Ricardo Faria E Almeida, M. Cicciu', Povilas Daugela, A. Ramanauskaite, N. Saulacic, T. Tervonen, Hom-lay Wang, Shan-Huey Yu
ABSTRACT Introduction The task of Group 3 was to review and update the existing data concerning non-surgical, surgical non-regenerative and surgical regenerative treatment of peri-implantitis. Special interest was paid to the preventive and supporting therapy in case of peri-implantitis. Material and Methods The main areas of interest were as follows: effect of smoking and history of periodontitis, prosthetic treatment mistakes, excess cement, overloading, general diseases influence on peri-implantitis development. The systematic review and/or meta-analysis were registered in PROSPERO, an international prospective register of systematic reviews: http://www.crd.york.ac.uk/PROSPERO/. The literature in the corresponding areas of interest was searched and reported using the PRISMA (Preferred Reporting Item for Systematic Review and Meta-Analysis) Statement: http://www.prisma-statement.org/. The method of preparation of systematic reviews of the literature based on comprehensive search strategies was discussed and standardized. The summary of the materials and methods employed by the authors in preparing the systematic review and/or meta-analysis is presented in Preface chapter. Results The results and conclusions of the review process are presented in the respective papers. The group′s general commentaries, consensus statements, clinical recommendations and implications for research are presented in this article.
{"title":"The 1st Baltic Osseointegration Academy and Lithuanian University of Health Sciences Consensus Conference 2016. Summary and Consensus Statements: Group III - Peri-Implantitis Treatment","authors":"F. Suárez-López Del Amo, Ricardo Faria E Almeida, M. Cicciu', Povilas Daugela, A. Ramanauskaite, N. Saulacic, T. Tervonen, Hom-lay Wang, Shan-Huey Yu","doi":"10.5037/jomr.2016.7316","DOIUrl":"https://doi.org/10.5037/jomr.2016.7316","url":null,"abstract":"ABSTRACT Introduction The task of Group 3 was to review and update the existing data concerning non-surgical, surgical non-regenerative and surgical regenerative treatment of peri-implantitis. Special interest was paid to the preventive and supporting therapy in case of peri-implantitis. Material and Methods The main areas of interest were as follows: effect of smoking and history of periodontitis, prosthetic treatment mistakes, excess cement, overloading, general diseases influence on peri-implantitis development. The systematic review and/or meta-analysis were registered in PROSPERO, an international prospective register of systematic reviews: http://www.crd.york.ac.uk/PROSPERO/. The literature in the corresponding areas of interest was searched and reported using the PRISMA (Preferred Reporting Item for Systematic Review and Meta-Analysis) Statement: http://www.prisma-statement.org/. The method of preparation of systematic reviews of the literature based on comprehensive search strategies was discussed and standardized. The summary of the materials and methods employed by the authors in preparing the systematic review and/or meta-analysis is presented in Preface chapter. Results The results and conclusions of the review process are presented in the respective papers. The group′s general commentaries, consensus statements, clinical recommendations and implications for research are presented in this article.","PeriodicalId":230885,"journal":{"name":"Journal of Oral & Maxillofacial Research","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132170441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ABSTRACT Objectives To study the efficacy of supportive peri-implant therapies in preventing clinical and radiological signs of peri-implantitis and implant loss. Material and Methods Longitudinal human studies, published between January 1, 2006, and February 1, 2016, were included based on an electronic search using MEDLINE and EMBASE databases and complemented by a manual search. Articles were included only if 1) they comprised a group of patients involved in/adhering to regular supportive peri-implant therapies (SPTs) and a control group without such therapies or with poor adherence to them, 2) the protocol of the SPTs was clearly described and 3) the outcome was indicated by means of clinical/radiological changes or implant loss. Results After initially identifying a total of 710 titles and abstracts, 12 full text articles were selected for eligibility assessment. Seven studies, three prospective and four retrospective, fulfilled the inclusion criteria for this review. The frequency of recall visits varied between the studies from a minimum of one visit every three months to an individually tailored regimen. In all the studies a lack of SPTs or poor adherence to them resulted in significantly higher frequencies of sites with mucosal bleeding, deepened peri-implant pockets or alveolar bone loss. In line with the above, a lack of/poor adherence to SPTs was associated with higher implant loss. Conclusions To prevent peri-implantitis, an individually tailored supportive programme based on patient motivation and re-instruction in oral hygiene measures combined with professional implant cleaning seem to be crucial.
{"title":"The Efficacy of Supportive Peri-Implant Therapies in Preventing Peri-Implantitis and Implant Loss: a Systematic Review of the Literature","authors":"A. Ramanauskaite, T. Tervonen","doi":"10.5037/jomr.2016.7312","DOIUrl":"https://doi.org/10.5037/jomr.2016.7312","url":null,"abstract":"ABSTRACT Objectives To study the efficacy of supportive peri-implant therapies in preventing clinical and radiological signs of peri-implantitis and implant loss. Material and Methods Longitudinal human studies, published between January 1, 2006, and February 1, 2016, were included based on an electronic search using MEDLINE and EMBASE databases and complemented by a manual search. Articles were included only if 1) they comprised a group of patients involved in/adhering to regular supportive peri-implant therapies (SPTs) and a control group without such therapies or with poor adherence to them, 2) the protocol of the SPTs was clearly described and 3) the outcome was indicated by means of clinical/radiological changes or implant loss. Results After initially identifying a total of 710 titles and abstracts, 12 full text articles were selected for eligibility assessment. Seven studies, three prospective and four retrospective, fulfilled the inclusion criteria for this review. The frequency of recall visits varied between the studies from a minimum of one visit every three months to an individually tailored regimen. In all the studies a lack of SPTs or poor adherence to them resulted in significantly higher frequencies of sites with mucosal bleeding, deepened peri-implant pockets or alveolar bone loss. In line with the above, a lack of/poor adherence to SPTs was associated with higher implant loss. Conclusions To prevent peri-implantitis, an individually tailored supportive programme based on patient motivation and re-instruction in oral hygiene measures combined with professional implant cleaning seem to be crucial.","PeriodicalId":230885,"journal":{"name":"Journal of Oral & Maxillofacial Research","volume":"229 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130551994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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