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Surgical Non-Regenerative Treatments for Peri-Implantitis: a Systematic Review 种植体周围炎的非再生外科治疗:系统综述
Pub Date : 2016-09-09 DOI: 10.5037/jomr.2016.7314
A. Ramanauskaite, Povilas Daugela, Ricardo Faria de Almeida, N. Saulacic
ABSTRACT Objectives The purposes of the present study were 1) to systematically review the literature on the surgical non-regenerative treatments of peri-implantitis and 2) to determine a predictable therapeutic option for the clinical management of peri-implantitis lesions. Material and Methods The study search was performed on primary database MEDLINE and EMBASE from 2005 until 2016. Sequential screenings at the title, abstract, and full-text levels were performed. Clinical human studies in the English language that had reported changes in probing depth (PD) and/or bleeding on probing (BOP) and/or radiologic marginal bone level changes after peri-implantitis surgical non-regenerative treatment at 6-month follow-up or longer were included accordingly PRISMA guidelines. Results The first electronic and hand search resulted in 765 citations. From 16 full-text articles reviewed, 6 were included in this systematic review. Surgical non-regenerative methods were found to be efficient in reducing clinical parameters. BOP and PD values were significantly decreased following implantoplasty and systematic administration of antibacterials, but not after local application of chemical compounds or diode laser. Similarly, significant improvement in clinical and radiographic parameters was found only after implantoplasty compared with resective surgery alone. We found significant heterogeneity in study designs and treatments provided among the pooled studies. All of the studies revealed an unclear or high risk of bias. Conclusions Surgical non-regenerative treatment of peri-implantitis was found to be effective to reduce the soft tissue inflammation and decrease probing depth. More randomized controlled clinical trials are needed to assess the efficacy of surgical non-regenerative therapy of peri-implantitis.
摘要目的本研究的目的是:1)系统地回顾关于种植周炎手术非再生治疗的文献;2)为临床治疗种植周炎病变确定可预测的治疗方案。材料与方法本研究检索于2005 - 2016年在主数据库MEDLINE和EMBASE中进行。在标题、摘要和全文水平上进行顺序筛选。在6个月或更长时间的随访中,英语临床人类研究报告了种植体周围手术非再生治疗后探探深度(PD)和/或探探出血(BOP)和/或放射学边缘骨水平的变化,因此纳入PRISMA指南。结果第一次电子检索和手工检索共获得765篇引文。从16篇全文综述中,6篇纳入本系统综述。手术非再生方法被发现是有效的减少临床参数。BOP和PD值在种植成形术和系统使用抗菌药物后显著降低,但在局部应用化合物或二极管激光后没有显著降低。同样,与单独切除性手术相比,仅种植成形术后临床和影像学参数有显著改善。我们发现在合并研究中提供的研究设计和治疗存在显著的异质性。所有的研究都显示了不明确或高的偏倚风险。结论手术治疗种植体周围炎可有效减轻软组织炎症,减少探探深度。需要更多的随机对照临床试验来评估手术非再生治疗种植体周围炎的疗效。
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引用次数: 41
Risk Factors for Peri-Implantitis: Effect of History of Periodontal Disease and Smoking Habits. A Systematic Review and Meta-Analysis 种植体周围炎的危险因素:牙周病史和吸烟习惯的影响。系统回顾和荟萃分析
Pub Date : 2016-09-09 DOI: 10.5037/jomr.2016.7303
C. Stacchi, F. Berton, G. Perinetti, A. Frassetto, T. Lombardi, Aiman Khoury, Francesca Andolsek, R. Di Lenarda
ABSTRACT Objectives The purpose of this review was to evaluate whether history of periodontitis and smoking habits could represent a risk factor for peri-implantitis and implant loss. Material and Methods This systematic review followed PRISMA guidelines and was registered at the PROSPERO database [registration numbers CRD42016034160 (effect of history of periodontitis) and CRD42016033676 (effect of smoking)]. Broad electronic (MEDLINE) and manual searches were conducted among articles published from January 1st 1990 up to December 31st 2015, resulting in 49332 records for history of periodontitis and 3199 for smoking habits. Selection criteria included prospective studies comparing two cohorts of patients, with and without the investigated risk factor, with a minimum follow-up period of three years, and reporting data on peri-implantitis and implant loss occurrence. Considering that only prospective studies were included, dichotomous data were expressed as risk ratios and 95% confidence intervals. Results Three studies evaluating history of periodontitis (on which quantitative analysis was performed) and one study on smoking effect were included. Both implant and patient-based meta-analyses revealed a significantly higher risk of developing peri-implantitis in patients with a history of periodontitis compared with periodontally healthy subjects, but not a statistically significant increased risk for implant loss. Conclusions The outcomes of this systematic review indicate history of periodontitis as a possible risk factor for peri-implantitis, while insufficient data are present in literature to evaluate the role of smoking. However, available evidence is still weak and immature, and sound epidemiological studies are needed to analyse the specific contribution of these potential risk factors.
摘要目的本综述的目的是评估牙周炎病史和吸烟习惯是否可能是种植体周围炎和种植体丢失的危险因素。本系统评价遵循PRISMA指南,并在PROSPERO数据库注册[注册号CRD42016034160(牙周炎病史的影响)和CRD42016033676(吸烟的影响)]。对1990年1月1日至2015年12月31日期间发表的文章进行了广泛的电子(MEDLINE)和人工检索,结果有49332条牙周炎史记录和3199条吸烟习惯记录。选择标准包括前瞻性研究,比较两组患者,有或没有所调查的危险因素,至少随访3年,并报告种植体周围炎和种植体丢失发生的数据。考虑到只纳入前瞻性研究,二分类数据用风险比和95%置信区间表示。结果纳入评估牙周炎病史的3项研究(进行了定量分析)和吸烟影响的1项研究。基于种植体和患者的荟萃分析显示,与牙周健康的受试者相比,有牙周炎病史的患者发生种植周炎的风险明显更高,但种植体丢失的风险没有统计学上的显著增加。结论:本系统综述的结果表明牙周炎病史可能是种植周炎的危险因素,而文献中没有足够的数据来评估吸烟的作用。然而,现有的证据仍然薄弱和不成熟,需要进行可靠的流行病学研究来分析这些潜在危险因素的具体作用。
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引用次数: 64
The 1st Baltic Osseointegration Academy and Lithuanian University of Health Sciences Consensus Conference 2016. Summary and Consensus Statements: Group II - Peri-Implantitis Diagnostics and Decision Tree 第一届波罗的海骨整合学会和立陶宛健康科学大学共识会议2016。总结和共识声明:第二组-种植体周围炎诊断和决策树
Pub Date : 2016-09-09 DOI: 10.5037/jomr.2016.7311
T. Tözüm, E. Dursun, P. Galindo-Moreno, G. Juodzbalys, Jesús López-Martínez, F. O’Valle, M. Padial-Molina, A. Ramanauskaite
ABSTRACT Introduction The task of Group 2 was to review and update the existing data concerning clinical and genetic methods of diagnostics of peri-implantitis. Special interest was paid to the peri-implant crevicular fluid (PICF) overview including analysis of enzymes and biomarkers and microbial profiles from implants. Material and Methods The main areas of interest were as follows: effect of smoking and history of periodontitis, prosthetic treatment mistakes, excess cement, overloading, general diseases influence on peri-implantitis development. The systematic review and/or meta-analysis were registered in PROSPERO, an international prospective register of systematic reviews: http://www.crd.york.ac.uk/PROSPERO/. The literature in the corresponding areas of interest was searched and reported using the PRISMA (Preferred Reporting Item for Systematic Review and Meta-Analysis) Statement: http://www.prisma-statement.org/. The method of preparation of systematic reviews of the literature based on comprehensive search strategies was discussed and standardized. The summary of the materials and methods employed by the authors in preparing the systematic review and/or meta-analysis is presented in Preface chapter. Results The results and conclusions of the review process are presented in the respective papers. The group′s general commentaries, consensus statements, clinical recommendations and implications for research are presented in this article.
第2组的任务是回顾和更新有关种植体周围炎诊断的临床和遗传学方法的现有数据。特别关注种植体周围沟液(PICF)概述,包括酶和生物标志物以及种植体微生物谱的分析。材料和方法主要关注以下方面:吸烟和牙周炎史的影响,假体治疗错误,过量骨水泥,超载,一般疾病对种植周炎发展的影响。该系统评价和/或荟萃分析已在国际前瞻性系统评价注册网站PROSPERO注册:http://www.crd.york.ac.uk/PROSPERO/。检索相关领域的文献并使用PRISMA(系统评价和荟萃分析首选报告项目)声明进行报告:http://www.prisma-statement.org/。讨论并规范了基于综合检索策略的文献系统综述的编制方法。作者在准备系统评价和/或荟萃分析时使用的材料和方法的总结在序言章节中提出。结果综述过程的结果和结论分别发表在各自的论文中。该小组的一般评论,共识声明,临床建议和研究的意义在这篇文章中提出。
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引用次数: 6
Surgical Regenerative Treatments for Peri-Implantitis: Meta-analysis of Recent Findings in a Systematic Literature Review 种植体周围炎的外科再生治疗:系统文献综述中最近发现的荟萃分析
Pub Date : 2016-09-09 DOI: 10.5037/jomr.2016.7315
Povilas Daugela, M. Cicciu', N. Saulacic
ABSTRACT Objectives The purpose of the present study was to systematically review the literature on the surgical regenerative treatment of the peri-implantitis and to determine an effective therapeutic predictable option for their clinical management. Material and Methods The study searched MEDLINE and EMBASE databases from 2006 to 2016. Clinical human studies that had reported changes in probing depth (PD) and/or bleeding on probing (BOP) and/or radiologic marginal bone level (RBL) changes after peri-implantitis surgical treatment at 12-month follow-up or longer were included accordingly to PRISMA guidelines. Results The initial search obtained 883 citations. After screening and determination of eligibility, 18 articles were included in the review. The meta-analysis of selected studies revealed that the weighted mean RBL fill was 1.97 mm (95% confidence interval [CI] = 1.58 to 2.35 mm), PD reduction was 2.78 mm (95% CI = 2.31 to 3.25 mm), and BOP reduced by 52.5% (95% CI = 41.6 to 63.1%). Defect fill in studies using and not using barrier membranes for graft coverage was 1.86 mm (95% CI = 1.36 to 2.36 mm) and 2.12 mm (95% CI = 1.46 to 2.78 mm) correspondingly. High heterogeneity among the studies regarding defects morphology, surgical protocols, and selection of biomaterials were found. Conclusions All included studies underlined an improvement of clinical conditions after the surgical regenerative treatment of peri-implantitis, however, there is a lack of scientific evidence in the literature regarding the superiority of the regenerative versus non-regenerative surgical treatment. The presence of a barrier membrane or submergence in the regenerative procedure does not seem to be fundamental in order to obtain clinical success of the surgery.
摘要目的本研究的目的是系统地回顾关于手术再生治疗种植体周围炎的文献,并确定其临床管理的有效治疗可预测的选择。材料与方法本研究检索了2006 - 2016年的MEDLINE和EMBASE数据库。临床人类研究报告在种植体周围手术治疗后12个月或更长时间的探探深度(PD)和/或探探出血(BOP)和/或放射学边缘骨水平(RBL)变化,根据PRISMA指南纳入。结果初步检索得到883条引文。在筛选和确定合格性后,18篇文章被纳入综述。对所选研究的荟萃分析显示,加权平均RBL填充为1.97 mm(95%可信区间[CI] = 1.58至2.35 mm), PD减少为2.78 mm (95% CI = 2.31至3.25 mm), BOP减少52.5% (95% CI = 41.6至63.1%)。在使用和不使用屏障膜进行移植物覆盖的研究中,缺陷填充分别为1.86 mm (95% CI = 1.36至2.36 mm)和2.12 mm (95% CI = 1.46至2.78 mm)。在缺损形态、手术方案和生物材料选择的研究中发现了高度的异质性。所有纳入的研究都强调了手术再生治疗种植体周围炎后临床状况的改善,然而,文献中缺乏关于再生与非再生手术治疗优越性的科学证据。再生过程中屏障膜或浸润的存在似乎并不是获得临床手术成功的基础。
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引用次数: 51
Diagnostic Principles of Peri-Implantitis: a Systematic Review and Guidelines for Peri-Implantitis Diagnosis Proposal 种植体周围炎的诊断原则:系统综述和种植体周围炎诊断建议指南
Pub Date : 2016-09-09 DOI: 10.5037/jomr.2016.7308
A. Ramanauskaite, G. Juodzbalys
ABSTRACT Objectives To review and summarize the literature concerning peri-implantitis diagnostic parameters and to propose guidelines for peri-implantitis diagnosis. Material and Methods An electronic literature search was conducted of the MEDLINE (Ovid) and EMBASE databases for articles published between 2011 and 2016. Sequential screening at the title/abstract and full-text levels was performed. Systematic reviews/guidelines of consensus conferences proposing classification or suggesting diagnostic parameters for peri-implantitis in the English language were included. The review was recorded on PROSPERO system with the code CRD42016033287. Results The search resulted in 10 articles that met the inclusion criteria. Four were papers from consensus conferences, two recommended diagnostic guidelines, three proposed classification of peri-implantitis, and one suggested an index for implant success. The following parameters were suggested to be used for peri-implantitis diagnosis: pain, mobility, bleeding on probing, probing depth, suppuration/exudate, and radiographic bone loss. In all of the papers, different definitions of peri-implantitis or implant success, as well as different thresholds for the above mentioned clinical and radiographical parameters, were used. Current evidence rationale for the diagnosis of peri-implantitis and classification based on consecutive evaluation of soft-tissue conditions and the amount of bone loss were suggested. Conclusions Currently there is no single uniform definition of peri-implantitis or the parameters that should be used. Rationale for diagnosis and prognosis of peri-implantitis as well as classification of the disease is proposed.
目的回顾和总结有关种植体周围炎诊断参数的文献,提出种植体周围炎的诊断指南。材料与方法在MEDLINE (Ovid)和EMBASE数据库中检索2011 - 2016年间发表的文章。在标题/摘要和全文水平上进行顺序筛选。系统评价/指南的共识会议提出分类或建议诊断参数的种植体周围炎在英语语言包括。评审记录在PROSPERO系统上,代码为CRD42016033287。结果检索到10篇符合纳入标准的文献。四篇是来自共识会议的论文,两篇是推荐的诊断指南,三篇是种植体周围炎的分类建议,一篇是种植体成功的指标建议。以下参数被建议用于种植体周围炎的诊断:疼痛、活动、探探时出血、探探深度、化脓/渗出和x线骨丢失。在所有的论文中,对种植体周围炎或种植体成功使用了不同的定义,以及上述临床和影像学参数的不同阈值。目前的证据基础的诊断种植体周围炎和分类基于连续评估软组织状况和骨质流失的量被建议。结论目前对种植体周围炎没有统一的定义或应采用的参数。本文提出了种植体周围炎的诊断、预后及分类的基本原理。
{"title":"Diagnostic Principles of Peri-Implantitis: a Systematic Review and Guidelines for Peri-Implantitis Diagnosis Proposal","authors":"A. Ramanauskaite, G. Juodzbalys","doi":"10.5037/jomr.2016.7308","DOIUrl":"https://doi.org/10.5037/jomr.2016.7308","url":null,"abstract":"ABSTRACT Objectives To review and summarize the literature concerning peri-implantitis diagnostic parameters and to propose guidelines for peri-implantitis diagnosis. Material and Methods An electronic literature search was conducted of the MEDLINE (Ovid) and EMBASE databases for articles published between 2011 and 2016. Sequential screening at the title/abstract and full-text levels was performed. Systematic reviews/guidelines of consensus conferences proposing classification or suggesting diagnostic parameters for peri-implantitis in the English language were included. The review was recorded on PROSPERO system with the code CRD42016033287. Results The search resulted in 10 articles that met the inclusion criteria. Four were papers from consensus conferences, two recommended diagnostic guidelines, three proposed classification of peri-implantitis, and one suggested an index for implant success. The following parameters were suggested to be used for peri-implantitis diagnosis: pain, mobility, bleeding on probing, probing depth, suppuration/exudate, and radiographic bone loss. In all of the papers, different definitions of peri-implantitis or implant success, as well as different thresholds for the above mentioned clinical and radiographical parameters, were used. Current evidence rationale for the diagnosis of peri-implantitis and classification based on consecutive evaluation of soft-tissue conditions and the amount of bone loss were suggested. Conclusions Currently there is no single uniform definition of peri-implantitis or the parameters that should be used. Rationale for diagnosis and prognosis of peri-implantitis as well as classification of the disease is proposed.","PeriodicalId":230885,"journal":{"name":"Journal of Oral & Maxillofacial Research","volume":"111 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131747675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 47
The 1st Baltic Osseointegration Academy and Lithuanian University of Health Sciences Consensus Conference 2016. Summary and Consensus Statements: Group I - Peri-Implantitis Aetiology, Risk Factors and Pathogenesis 第一届波罗的海骨整合学会和立陶宛健康科学大学共识会议2016。总结和共识声明:第一组-种植体周围炎的病因、危险因素和发病机制
Pub Date : 2016-09-09 DOI: 10.5037/jomr.2016.7307
C. Stacchi, Francesca Andolsek, I. Astramskaitė, F. Berton, R. Di Lenarda, M. Fernandes, A. Frassetto, P. Gomes, Žygimantas Guobis, R. Jimbo, G. Juodzbalys, Aiman Khoury, R. Kubilius, R. Kuoppala, T. Lombardi, J. Maminskas, I. Pacauskiene, G. Perinetti, L. Poskevicius, Mindaugas Pranskunas, A. Puišys, A. Raustia
ABSTRACT Introduction The task of Group 1 was to review and update the existing data concerning aetiology, risk factors and pathogenesis of peri-implantitis. Previous history of periodontitis, poor oral hygiene, smoking and presence of general diseases have been considered among the aetiological risk factors for the onset of peri-implant pathologies, while late dental implant failures are commonly associated with peri-implantitis and/or with the application of incorrect biomechanical forces. Special interest was paid to the bone cells dynamics as part of the pathogenesis of peri-implantitis. Material and Methods The main areas indagated by this group were as follows: influence of smoking, history of periodontitis and general diseases on peri-implantitis development, bio-mechanics of implant loading and its influence on peri-implant bone and cellular dynamics related to the pathogenesis of peri-implantitis. The systematic reviews and/or meta-analyses were registered in PROSPERO, an international prospective register of systematic reviews: http://www.crd.york.ac.uk/PROSPERO/. The literature in the corresponding areas of interest was screened and reported following the PRISMA (Preferred Reporting Item for Systematic Review and Meta-Analysis) Statement: http://www.prisma-statement.org/. Method of preparation of the systematic reviews, based on comprehensive search strategies, was discussed and standardized. The summary of the materials and methods employed by the authors in preparing the systematic reviews and/or meta-analyses is presented in Preface chapter. Results The results and conclusions of the review process are presented in the respective papers. One systematic review with meta-analysis, three systematic reviews and one theoretical analysis were performed. The group′s general commentaries, consensus statements, clinical recommendations and implications for research are presented in this article.
第1组的任务是回顾和更新有关种植体周围炎的病因、危险因素和发病机制的现有资料。牙周炎病史、口腔卫生不良、吸烟和一般疾病的存在被认为是引起种植体周围病变的病因危险因素,而晚期种植体失败通常与种植体周围炎和/或应用不正确的生物力学力有关。特别感兴趣的是骨细胞动力学作为种植体周围炎发病机制的一部分。材料与方法本组研究主要涉及吸烟、牙周炎病史及一般疾病对种植周炎发展的影响、种植体负重的生物力学及其对种植周骨的影响、与种植周炎发病机制相关的细胞动力学。系统评价和/或荟萃分析在国际前瞻性系统评价注册网站PROSPERO上注册:http://www.crd.york.ac.uk/PROSPERO/。根据PRISMA(系统评价和荟萃分析首选报告项目)声明:http://www.prisma-statement.org/对相关领域的文献进行筛选和报告。讨论并规范了基于综合检索策略的系统综述的编制方法。作者在准备系统综述和/或荟萃分析时使用的材料和方法的总结在序言章节中提出。结果综述过程的结果和结论分别发表在各自的论文中。进行了一项系统综述和荟萃分析,三项系统综述和一项理论分析。该小组的一般评论,共识声明,临床建议和研究的意义在这篇文章中提出。
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引用次数: 4
The Prosthetic Influence and Biomechanics on Peri-Implant Strain: a Systematic Literature Review of Finite Element Studies 假体对种植体周围应变的影响和生物力学:有限元研究的系统文献综述
Pub Date : 2016-09-09 DOI: 10.5037/jomr.2016.7304
J. Maminskas, A. Puišys, R. Kuoppala, A. Raustia, G. Juodzbalys
ABSTRACT Objectives To systematically review risks of mechanical impact on peri-implant strain and prosthetic influence on stability across finite element studies. Material and Methods An online literature search was performed on MEDLINE and EMBASE databases published between 2011 and 2016. Following keywords tiered screening and selection of the title, abstract and full-text were performed. Studies of finite element analysis (FEA) were considered for inclusion that were written in English and revealed stress concentrations or strain at peri-implant bone level. Results There were included 20 FEA studies in total. Data were organized according to the following topics: bone layers, type of bone, osseointegration level, bone level, design of implant, diameter and length of implant, implant-abutment connection, type of supra-construction, loading axis, measurement units. The stress or strain at implant-bone contact was measured over all studies and numerical values estimated. Risks of overloading were accented as non-axial loading, misfits, cantilevers and the stability of peri-implant bone was related with the usage of platform switch connection of abutment. Conclusions Peri-implant area could be affected by non-axial loading, cantilever prosthetic elements, crown/implant ratio, type of implant-abutment connection, misfits, properties of restoration materials and antagonistic tooth. The heterogeneity of finite element analysis studies limits systematization of data. Results of these studies are comparable with other findings of in vitro, in vivo, prospective and retrospective studies.
目的通过有限元研究系统回顾机械影响种植体周围应变的风险和假体对稳定性的影响。材料与方法对2011 - 2016年出版的MEDLINE和EMBASE数据库进行在线文献检索。对关键词进行分层筛选,选择题目、摘要和全文。考虑纳入用英文写的有限元分析(FEA)研究,并显示种植体周围骨水平的应力集中或应变。结果共纳入20项有限元分析。数据按照以下主题进行整理:骨层、骨类型、骨整合水平、骨水平、种植体设计、种植体直径和长度、种植体-基台连接、超结构类型、加载轴、测量单位。在所有研究中测量了种植体与骨接触时的应力或应变,并估计了数值。非轴向载荷、错位、悬臂以及种植周骨的稳定性与基台平台开关连接的使用有关,都是超载的风险。结论非轴向载荷、悬臂式假体、冠/种植体比例、种植体-基台连接方式、不匹配、修复材料特性和拮抗牙均可影响种植体周围面积。有限元分析研究的异质性限制了数据的系统化。这些研究的结果与其他体外、体内、前瞻性和回顾性研究的结果具有可比性。
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引用次数: 52
General Diseases Influence on Peri-Implantitis Development: a Systematic Review 一般疾病对种植体周围炎发展的影响:系统综述
Pub Date : 2016-09-09 DOI: 10.5037/jomr.2016.7305
Žygimantas Guobis, I. Pacauskiene, I. Astramskaitė
ABSTRACT Objectives To systematically review the influence of systemic diseases or medications used in their treatment on the dental implant therapy success. Material and Methods The search strategy was implemented on the National Library of Medicine database (MEDLINE) (Ovid) and EMBASE electronic databases between January 2006 and January 2016. Human studies with available English articles analysing the relationship between dental implant therapy success and systemic diseases, such as diabetes mellitus, AIDS/HIV, rheumatoid arthritis, osteoporosis, Crohn’s disease, cardiovascular diseases, scleroderma, Sjögren’s syndrome, lichen planus, ectodermal dysplasia, post-transplantation status, were included in present review according to the PRISMA guidelines. The review protocol was registered on PROSPERO system with the code CRD42016033662. Results Present review included forty one retrospective and prospective follow-up studies, case-control studies, case report series and cohort studies. Despite some limitations this study reveals positive results of implantation in most systemic conditions that should be interpreted with caution. Influence of cardiovascular diseases on the dental implantation success should be explored deeply, because of controversial results and likelihood of comorbidity expressed by a history of cardiovascular diseases and periodontitis. There is only a weak relationship with bone density in osteoporosis and implant failure. All the other diseases did not show significant effect on implantation success. Conclusions Recent studies with low strength of evidence and controversy show that systemic diseases may have potential effect on the success of implantation, but further detailed studies are needed to provide these findings.
【摘要】目的系统回顾全身性疾病或治疗中使用的药物对种植体治疗成功的影响。材料与方法检索策略于2006年1月至2016年1月在美国国家医学图书馆数据库(MEDLINE) (Ovid)和EMBASE电子数据库中实施。根据PRISMA指南,本综述纳入了现有英文文章的人类研究,分析了种植牙治疗成功与全身性疾病(如糖尿病、艾滋病/艾滋病毒、类风湿关节炎、骨质疏松症、克罗恩病、心血管疾病、硬皮病、Sjögren综合征、扁平苔藓、外胚层发育不良、移植后状态)之间的关系。审查方案在PROSPERO系统上注册,代码为CRD42016033662。结果本综述包括41项回顾性和前瞻性随访研究、病例对照研究、病例报告系列研究和队列研究。尽管存在一些局限性,但本研究揭示了植入在大多数全身情况下的积极结果,应谨慎解释。心血管疾病对种植牙成功的影响应深入探讨,因为结果存在争议,并且心血管疾病和牙周炎病史可能表现为共病。骨质疏松症和种植体失败与骨密度的关系很弱。其他疾病对植入成功无明显影响。结论近期一些证据强度低且存在争议的研究表明,全身性疾病可能对植入成功有潜在影响,但需要进一步的详细研究来证实这些发现。
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引用次数: 53
PREFACE. The 1st Baltic Osseointegration Academy and Lithuanian University of Health Sciences Consensus Conference 9 - 10 September 2016, Kaunas, Lithuania 前言。第一届波罗的海骨整合学会和立陶宛健康科学大学共识会议2016年9月9日至10日,立陶宛考纳斯
Pub Date : 2016-09-09 DOI: 10.5037/jomr.2016.7301
G. Juodzbalys
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引用次数: 0
Influence of Peri-Implant Soft Tissue Condition and Plaque Accumulation on Peri-Implantitis: a Systematic Review 种植体周围软组织状况和菌斑积累对种植体周围炎的影响:系统综述
Pub Date : 2016-09-09 DOI: 10.5037/jomr.2016.7302
Mindaugas Pranskunas, L. Poskevicius, G. Juodzbalys, R. Kubilius, R. Jimbo
ABSTRACT Objectives To systematically examine influence of soft tissue condition and plaque accumulation around dental implants on peri-implantitis development. Material and Methods An electronic literature search was conducted of two databases - MEDLINE (Ovid) and EMBASE from 2011 to 2016. Sequential screenings at the title, abstract, and full-text levels were performed. Clinical human studies in the English language that had reported soft tissue condition or plaque accumulation influence on peri-implantitis development were included. The resulting articles were independently subjected to clear inclusion and exclusion criteria by two reviewers as follows. Results The search resulted in 8 articles meeting the inclusion criteria. These studies reported gingival index, plaque index, pocket depth, bleeding on probing/modified bleeding index for sites with “adequate” (≥ 2 mm) and “inadequate” (< 2 mm) width of keratinized mucosa. Results demonstrated that the amount of keratinized mucosa has little influence on soft-tissue inflammation in the presence of good oral hygiene. However, suboptimal oral hygiene due to difficulty in access for plaque control in the areas of minimal keratinized mucosa may lead to greater tissue damage. Conclusions In cases with insufficient keratinized gingiva in the vicinity of implants, the insufficiency does not necessarily mediate adverse effects on the hygiene management and soft tissue health condition. Nonetheless, the risk of the increase of gingival index, plaque index, pocket depth, bleeding on probing/modified bleeding index is present. Therefore, the presence of an appropriate amount of keratinized gingiva is required.
目的系统研究种植体周围软组织状况和菌斑积累对种植体周围炎发展的影响。材料与方法2011 - 2016年对MEDLINE (Ovid)和EMBASE两个数据库进行电子文献检索。在标题、摘要和全文水平上进行顺序筛选。包括用英语进行的临床人类研究,这些研究报告了软组织状况或斑块积累对种植体周围炎发展的影响。由此产生的文章由两位审稿人独立地进行明确的纳入和排除标准,如下所示。结果检索到8篇符合纳入标准的文献。这些研究报告了角化粘膜“足够”(≥2mm)和“不足”(< 2mm)宽度的部位的牙龈指数、斑块指数、口袋深度、探查出血/改良出血指数。结果表明,在良好的口腔卫生条件下,角质化黏膜的数量对软组织炎症的影响很小。然而,由于难以进入最小角化粘膜区域控制斑块,口腔卫生不佳可能导致更大的组织损伤。结论种植体附近角化牙龈不足并不一定会对卫生管理和软组织健康状况产生不良影响。尽管如此,仍存在牙龈指数、菌斑指数、牙袋深度、探查出血/改良出血指数增加的风险。因此,需要有适量的角质化牙龈。
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引用次数: 61
期刊
Journal of Oral & Maxillofacial Research
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