Pub Date : 2025-01-20Print Date: 2025-01-21DOI: 10.4045/tidsskr.24.0241
Erik Dissen, Erlend Hem
{"title":"Lymfeknuter er verken kjertler eller glandler.","authors":"Erik Dissen, Erlend Hem","doi":"10.4045/tidsskr.24.0241","DOIUrl":"https://doi.org/10.4045/tidsskr.24.0241","url":null,"abstract":"","PeriodicalId":23123,"journal":{"name":"Tidsskrift for Den Norske Laegeforening","volume":"145 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-20Print Date: 2025-01-21DOI: 10.4045/tidsskr.25.01.01
Are Brean
{"title":"Varmere og villere.","authors":"Are Brean","doi":"10.4045/tidsskr.25.01.01","DOIUrl":"https://doi.org/10.4045/tidsskr.25.01.01","url":null,"abstract":"","PeriodicalId":23123,"journal":{"name":"Tidsskrift for Den Norske Laegeforening","volume":"145 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-20Print Date: 2025-01-21DOI: 10.4045/tidsskr.24.0507
Petter Andreas Ringen, Hallvard Solbø Hagen
{"title":"Bevisstheten kan forstås innenfra.","authors":"Petter Andreas Ringen, Hallvard Solbø Hagen","doi":"10.4045/tidsskr.24.0507","DOIUrl":"https://doi.org/10.4045/tidsskr.24.0507","url":null,"abstract":"","PeriodicalId":23123,"journal":{"name":"Tidsskrift for Den Norske Laegeforening","volume":"145 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-20Print Date: 2025-01-21DOI: 10.4045/tidsskr.24.0562
Mari Bjørnaas
{"title":"Time-expired emergency preparedness.","authors":"Mari Bjørnaas","doi":"10.4045/tidsskr.24.0562","DOIUrl":"https://doi.org/10.4045/tidsskr.24.0562","url":null,"abstract":"","PeriodicalId":23123,"journal":{"name":"Tidsskrift for Den Norske Laegeforening","volume":"145 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-16Print Date: 2025-01-21DOI: 10.4045/tidsskr.24.0583
Nils Erik Gilhus, Marit Berg Eldegard, Lillian Festvåg, Kari Lofthus, Anne-Kristine Schanke, Oddrunn Skogsholmen Dahlheim, Sigurd Aarrestad
{"title":"Postpolio-syndrom må få mer oppmerksomhet.","authors":"Nils Erik Gilhus, Marit Berg Eldegard, Lillian Festvåg, Kari Lofthus, Anne-Kristine Schanke, Oddrunn Skogsholmen Dahlheim, Sigurd Aarrestad","doi":"10.4045/tidsskr.24.0583","DOIUrl":"https://doi.org/10.4045/tidsskr.24.0583","url":null,"abstract":"","PeriodicalId":23123,"journal":{"name":"Tidsskrift for Den Norske Laegeforening","volume":"145 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-14Print Date: 2025-01-15DOI: 10.4045/tidsskr.25.0028
Kirsti Malterud
{"title":"Rettelse: Kunstig intelligens kan ikke utføre kvalitativ analyse.","authors":"Kirsti Malterud","doi":"10.4045/tidsskr.25.0028","DOIUrl":"https://doi.org/10.4045/tidsskr.25.0028","url":null,"abstract":"","PeriodicalId":23123,"journal":{"name":"Tidsskrift for Den Norske Laegeforening","volume":"145 ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-13Print Date: 2025-01-21DOI: 10.4045/tidsskr.25.0016
Are Brean
{"title":"Hands off the watchdog.","authors":"Are Brean","doi":"10.4045/tidsskr.25.0016","DOIUrl":"https://doi.org/10.4045/tidsskr.25.0016","url":null,"abstract":"","PeriodicalId":23123,"journal":{"name":"Tidsskrift for Den Norske Laegeforening","volume":"145 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-13Print Date: 2025-01-21DOI: 10.4045/tidsskr.24.0581
Geir Aamodt
{"title":"Romlige data i medisin og helsefag.","authors":"Geir Aamodt","doi":"10.4045/tidsskr.24.0581","DOIUrl":"https://doi.org/10.4045/tidsskr.24.0581","url":null,"abstract":"","PeriodicalId":23123,"journal":{"name":"Tidsskrift for Den Norske Laegeforening","volume":"145 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-13Print Date: 2025-01-21DOI: 10.4045/tidsskr.24.0231
Marthe Kopland, Vigdis Skinnemoen Ottersen, Dag Olav Dahle, Tobias Gedde-Dahl, Jakob Dalgaard
Background: When haemolytic anaemia, thrombocytopenia and renal failure are present, a thrombotic microangiopathic (TMA) condition should be suspected. We describe the various differential diagnoses of primary TMA syndromes, their clinical findings, clinical workup and treatment.
Case presentation: A previously healthy man in his fifties was hospitalised with anaemia, thrombocytopenia, bilirubinaemia and acute renal failure. He was in good general condition without neurological symptoms. Due to suspicion of thrombotic microangiopathy (mainly thrombotic thrombocytopenic purpura (TTP)), he was referred to a university clinic for immediate plasma exchange. His renal failure deteriorated and haemodialysis was initiated. However, ADAMTS13 level was normal. Thus, complement-mediated thrombotic microangiopathy was suspected and eculizumab was administered. Due to previous abdominal discomfort a faecal sampling was performed, detecting enterohaemorrhagic E. coli (EHEC) DNA (Shigatoxin 2f). Hence, the diagnosis was Shigatoxin-induced haemolytic uraemic syndrome (ST-HUS). Supportive care was continued and renal function normalised.
Interpretation: When thrombotic microangiopathy is suspected, an assessment is made whether to initiate plasmapheresis and immunomodulatory treatment. A thorough workup is needed to differentiate between the various primary TMA syndromes. Thus, treatment with expensive and possibly harmful drugs can be avoided. The various primary TMA syndromes have overlapping clinical features, and the diagnosis can be difficult.
{"title":"En mann i 50-årene med akutt nyresvikt, anemi og trombocytopeni.","authors":"Marthe Kopland, Vigdis Skinnemoen Ottersen, Dag Olav Dahle, Tobias Gedde-Dahl, Jakob Dalgaard","doi":"10.4045/tidsskr.24.0231","DOIUrl":"https://doi.org/10.4045/tidsskr.24.0231","url":null,"abstract":"<p><strong>Background: </strong>When haemolytic anaemia, thrombocytopenia and renal failure are present, a thrombotic microangiopathic (TMA) condition should be suspected. We describe the various differential diagnoses of primary TMA syndromes, their clinical findings, clinical workup and treatment.</p><p><strong>Case presentation: </strong>A previously healthy man in his fifties was hospitalised with anaemia, thrombocytopenia, bilirubinaemia and acute renal failure. He was in good general condition without neurological symptoms. Due to suspicion of thrombotic microangiopathy (mainly thrombotic thrombocytopenic purpura (TTP)), he was referred to a university clinic for immediate plasma exchange. His renal failure deteriorated and haemodialysis was initiated. However, ADAMTS13 level was normal. Thus, complement-mediated thrombotic microangiopathy was suspected and eculizumab was administered. Due to previous abdominal discomfort a faecal sampling was performed, detecting enterohaemorrhagic E. coli (EHEC) DNA (Shigatoxin 2f). Hence, the diagnosis was Shigatoxin-induced haemolytic uraemic syndrome (ST-HUS). Supportive care was continued and renal function normalised.</p><p><strong>Interpretation: </strong>When thrombotic microangiopathy is suspected, an assessment is made whether to initiate plasmapheresis and immunomodulatory treatment. A thorough workup is needed to differentiate between the various primary TMA syndromes. Thus, treatment with expensive and possibly harmful drugs can be avoided. The various primary TMA syndromes have overlapping clinical features, and the diagnosis can be difficult.</p>","PeriodicalId":23123,"journal":{"name":"Tidsskrift for Den Norske Laegeforening","volume":"145 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-10Print Date: 2025-01-21DOI: 10.4045/tidsskr.24.0571
Kirsti Malterud
{"title":"Kunstig intelligens kan ikke utføre kvalitativ analyse.","authors":"Kirsti Malterud","doi":"10.4045/tidsskr.24.0571","DOIUrl":"https://doi.org/10.4045/tidsskr.24.0571","url":null,"abstract":"","PeriodicalId":23123,"journal":{"name":"Tidsskrift for Den Norske Laegeforening","volume":"145 1","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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