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Fahr's disease or primary familial brain calcification? Fahr病还是原发性家族性脑钙化？
IF 1.2 Q2 MEDICINE, GENERAL & INTERNAL
Tidsskrift for Den Norske Laegeforening
Pub Date : 2025-04-21 Print Date: 2025-04-22 DOI: 10.4045/tidsskr.24.0606
Christina Wilhelmina Leerink, Henriette Aksnes
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引用次数: 0
Legelobbying og helsepolitiske prosesser i EU.
IF 1.2 Q2 MEDICINE, GENERAL & INTERNAL
Tidsskrift for Den Norske Laegeforening
Pub Date : 2025-04-21 Print Date: 2025-04-22 DOI: 10.4045/tidsskr.25.0149
Ole Johan Bakke
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引用次数: 0
Ibsen's wallet - an insight into the poet's prescriptions. 易卜生的钱包——洞察诗人的处方。
IF 1.2 Q2 MEDICINE, GENERAL & INTERNAL
Tidsskrift for Den Norske Laegeforening
Pub Date : 2025-04-19 Print Date: 2025-04-22 DOI: 10.4045/tidsskr.24.0526
Erlend Hem, Jan Frich

Background: In the spring of 2018, the Henrik Ibsen Museum in Skien was preparing for a new exhibition featuring the poet's personal possessions. During this process, they found a wallet containing three prescriptions. What medications were involved, what was the treatment for and could it have been harmful to him?

Material and method: We have studied the three prescriptions in light of information regarding Ibsen's health and the medical understanding and practices of the time.

Results and interpretation: The prescriptions show that Ibsen used potassium iodide, potassium bromide and uricedin, likely for arteriosclerosis, insomnia and constipation. One of the prescriptions was for Ibsen's wife, Suzannah, for an iodine-based medication in the form of sodium iodide. Ibsen likely started using these medications when Edvard Bull became his doctor in 1903. Given Bull's robust medical knowledge and exceptional, energetic monitoring of Ibsen's health, there is no reason to believe the treatment was harmful.

背景：2018年春天，位于Skien的亨里克·易卜生博物馆（Henrik Ibsen Museum）正准备举办一场新的展览，展出这位诗人的个人物品。在这个过程中，他们发现了一个装有三张处方的钱包。他服用了什么药物，治疗的目的是什么，会对他造成伤害吗？材料和方法：我们根据易卜生的健康信息和当时的医学认识和实践来研究这三种方剂。结果与解释：处方显示易卜生使用了碘化钾、溴化钾和尿苷，可能用于动脉硬化、失眠和便秘。其中一张处方是给易卜生的妻子苏珊娜的，是一种碘化钠的碘基药物。易卜生可能是在1903年爱德华·布尔成为他的医生后开始使用这些药物的。鉴于布尔丰富的医学知识和对易卜生健康状况的异常、积极的监测，没有理由相信这种治疗是有害的。
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引用次数: 0
Microbes as history's driving force. 微生物是历史的驱动力。
IF 1.2 Q2 MEDICINE, GENERAL & INTERNAL
Tidsskrift for Den Norske Laegeforening
Pub Date : 2025-04-19 Print Date: 2025-04-22 DOI: 10.4045/tidsskr.25.0100
Gunnar Skov Simonsen
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引用次数: 0
Physical activity and troponin elevation. 运动和肌钙蛋白升高。
IF 1.2 Q2 MEDICINE, GENERAL & INTERNAL
Tidsskrift for Den Norske Laegeforening
Pub Date : 2025-04-19 Print Date: 2025-04-20 DOI: 10.4045/tidsskr.25.0035
Erle Edvardsson, Torbjørn Omland
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引用次数: 0
Vestibularisschwannom – diagnostikk og behandling.
IF 1.2 Q2 MEDICINE, GENERAL & INTERNAL
Tidsskrift for Den Norske Laegeforening
Pub Date : 2025-04-17 Print Date: 2025-04-22 DOI: 10.4045/tidsskr.24.0398
Erlend Moen Taule, Dhanushan Dhayalan, Jan Erik Berge, Frederik Kragerud Goplen, Jeanette Hess-Erga, Morten Lund-Johansen, Tormund Haugland Njølstad, Øystein Vesterli Tveiten, Terje Sundstrøm

Vestibular schwannoma is a benign tumour originating from Schwann cells in the vestibular nerve. Each year, up to 250 patients in Norway are diagnosed with the condition. Treatment options are surgery, gamma knife radiosurgery or observation. The best treatment modality remains a topic of debate, and there are few high-quality comparative studies. With the ageing population and increasing access to MRI scans, the number of patients diagnosed with vestibular schwannoma is expected to rise. This clinical review article focuses on the diagnosis and treatment of vestibular schwannoma.

前庭神经鞘瘤是一种起源于前庭神经薛旺细胞的良性肿瘤。每年，挪威有多达250名患者被诊断出患有这种疾病。治疗选择有手术、伽玛刀放疗或观察。最好的治疗方式仍然是一个争论的话题，很少有高质量的比较研究。随着人口老龄化和MRI扫描的增加，被诊断为前庭神经鞘瘤的患者数量预计会增加。本文就前庭神经鞘瘤的诊断和治疗作一综述。
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引用次数: 0
Lower threshold for hormone therapy in women with multiple sclerosis. 多发性硬化症女性激素治疗的低阈值。
IF 1.2 Q2 MEDICINE, GENERAL & INTERNAL
Tidsskrift for Den Norske Laegeforening
Pub Date : 2025-04-17 Print Date: 2025-04-18 DOI: 10.4045/tidsskr.25.0070
Cecilia Smith Simonsen, Mette Haase Moen, Elisabeth Gulowsen Celius
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引用次数: 0
Kunstig intelligens i allmennmedisinen.
IF 1.2 Q2 MEDICINE, GENERAL & INTERNAL
Tidsskrift for Den Norske Laegeforening
Pub Date : 2025-04-17 Print Date: 2025-04-18 DOI: 10.4045/tidsskr.25.0161
Ingvild Vatten, Morten Munkvik
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引用次数: 0
Framework to-do for GPs. 全科医生的框架待办事项。
IF 1.2 Q2 MEDICINE, GENERAL & INTERNAL
Tidsskrift for Den Norske Laegeforening
Pub Date : 2025-04-11 Print Date: 2025-04-22 DOI: 10.4045/tidsskr.25.0243
Øyvind Stople Sivertsen
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引用次数: 0
Aortitis triggered by granulocyte-colony stimulating factor. 粒细胞集落刺激因子引发的主动脉炎。
IF 1.2 Q2 MEDICINE, GENERAL & INTERNAL
Tidsskrift for Den Norske Laegeforening
Pub Date : 2025-04-10 Print Date: 2025-04-22 DOI: 10.4045/tidsskr.24.0466
Andreas Gaustad, Marthe Halsan Liff, Aleksander Nordberg Nørgaard, Kristin Kiplesund Fremo, Robert Brudevold

Background: A man in his sixties was diagnosed with diffuse large B-cell lymphoma localised in the base of his tongue.

Case presentation: The patient was admitted to the emergency department with a fever, generalised muscle aches and lethargy 12 days atter receiving his first chemotherapy treatment with granulocyte-colony stimulating factor (G-CSF) supplementation. There were no focal signs of infection. The patient was started on empiric antibiotic treatment. After four days, C-reactive protein (CRP) had increased from 104 to 331, but the patient's condition was largely unchanged. A computer tomography (CT) scan showed aortitis, most likely caused by G-CSF. The patient was treated with prednisolone and rapidly improved.

Interpretation: The diagnosis of G-CSF-induced aortitis should be considered in patients with fever after G-CSF treatment, particularly if adequate antibiotic treatment does not lead to improvement. Advanced imaging is often indicated. The most important measure is to discontinue G-CSF supplementation.

背景：一位六十多岁的男性被诊断为舌底弥漫性大b细胞淋巴瘤。病例介绍：患者在接受第一次补充粒细胞集落刺激因子（G-CSF）化疗12天后，因发烧、全身肌肉疼痛和嗜睡而入院急诊科。没有局部感染的迹象。病人开始接受经验性抗生素治疗。四天后，c反应蛋白（CRP）从104上升到331，但患者的病情基本没有变化。计算机断层扫描（CT）显示主动脉炎，很可能是由G-CSF引起的。患者经强的松龙治疗后病情迅速好转。结论：G-CSF治疗后发热的患者应考虑G-CSF诱导的主动脉炎的诊断，特别是在充分的抗生素治疗没有导致改善的情况下。通常需要高级影像学检查。最重要的措施是停止补充G-CSF。
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引用次数: 0
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