Pub Date : 2023-05-17DOI: 10.1080/24734306.2023.2212539
W. Wesson, Rachel Stetson, H. Ganatra, Shawn B Sood
seizure is a rare but documented adverse event associated with ampicillin, which is one of the most commonly used antibiotics used in pediatrics. We report a case of a 4-month- old male infant with Haemophilus influenzae type a meningitis that experienced recurrent tonic-clonic seizures, possibly secondary to ampicillin treatment. after ampicillin administration was withdrawn and antiepileptic agents were administered, the seizures resolved, improving the patient’s clinical status rapidly. this case report adds to the growing body of literature on ampicillin-induced seizures.
{"title":"Ampicillin-induced seizures in a 4-month-old with bacterial meningitis: a case report","authors":"W. Wesson, Rachel Stetson, H. Ganatra, Shawn B Sood","doi":"10.1080/24734306.2023.2212539","DOIUrl":"https://doi.org/10.1080/24734306.2023.2212539","url":null,"abstract":"seizure is a rare but documented adverse event associated with ampicillin, which is one of the most commonly used antibiotics used in pediatrics. We report a case of a 4-month- old male infant with Haemophilus influenzae type a meningitis that experienced recurrent tonic-clonic seizures, possibly secondary to ampicillin treatment. after ampicillin administration was withdrawn and antiepileptic agents were administered, the seizures resolved, improving the patient’s clinical status rapidly. this case report adds to the growing body of literature on ampicillin-induced seizures.","PeriodicalId":23139,"journal":{"name":"Toxicology communications","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90620886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-12DOI: 10.1080/24734306.2023.2196811
Michael Mullins
{"title":"Abstracts of the Middle East and North Africa clinical Toxicology Association Meeting, January 11–14, 2023, Abu Dhabi, UAE","authors":"Michael Mullins","doi":"10.1080/24734306.2023.2196811","DOIUrl":"https://doi.org/10.1080/24734306.2023.2196811","url":null,"abstract":"","PeriodicalId":23139,"journal":{"name":"Toxicology communications","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77759891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-10DOI: 10.1080/24734306.2023.2203367
T. Hallett, L. Klein, Daniel Dunnavant, Allison J. Weatherly, Rebecca S Kidd, R. Bruccoleri
{"title":"Imaging use after 35% hydrogen peroxide ingestion by a 3-year-old: a case report","authors":"T. Hallett, L. Klein, Daniel Dunnavant, Allison J. Weatherly, Rebecca S Kidd, R. Bruccoleri","doi":"10.1080/24734306.2023.2203367","DOIUrl":"https://doi.org/10.1080/24734306.2023.2203367","url":null,"abstract":"","PeriodicalId":23139,"journal":{"name":"Toxicology communications","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75252914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-19DOI: 10.1080/24734306.2023.2201488
M. Alfaifi, B. Alyahya, Ibrahim Alhelali, L. M. Al-Murayeh, Ibrahim Al-Benhassan, Hesham M. Gamal, Mohamed Elbarbary, Hadi Al-Ali
{"title":"Black widow spider (Latrodectus renivulatus) envenomation in children in Saudi Arabia: a case series","authors":"M. Alfaifi, B. Alyahya, Ibrahim Alhelali, L. M. Al-Murayeh, Ibrahim Al-Benhassan, Hesham M. Gamal, Mohamed Elbarbary, Hadi Al-Ali","doi":"10.1080/24734306.2023.2201488","DOIUrl":"https://doi.org/10.1080/24734306.2023.2201488","url":null,"abstract":"","PeriodicalId":23139,"journal":{"name":"Toxicology communications","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85592112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-13DOI: 10.1080/24734306.2023.2174689
Christopher Martin, K. Harris, C. Wylie, K. Isoardi
{"title":"Rising prescription stimulant poisoning in Australia: a retrospective case series","authors":"Christopher Martin, K. Harris, C. Wylie, K. Isoardi","doi":"10.1080/24734306.2023.2174689","DOIUrl":"https://doi.org/10.1080/24734306.2023.2174689","url":null,"abstract":"","PeriodicalId":23139,"journal":{"name":"Toxicology communications","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80676889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-31DOI: 10.1080/24734306.2022.2143697
Abdulmajeed Al-Qutaiti, A. Al-Kashmiri, Amina Al rawahi, A. Abri
Injuries by marine creatures are a common presentation to Oman’s emergency departments (EDs). However, despite the difference in the marine fauna globally, there is no study on marine envenomation in Oman. We conducted a retrospective chart review of marine envenomation cases that presented to the ED at Khoula hospital, one of the main tertiary hospitals in Oman, between 2018 and 2019. We included patients of all ages who presented with injury secondary to contact with a marine creature. Multiple parameters were recorded, including causative creatures, symptoms, and medications. A total of 78 cases were included in this study, the majority (67.9%) were adults (18–64 years), and 82.1% were males. sea urchins accounted for most envenomations (52.6%). the pain was the most common presenting symptom (65.4%). the most common medication received in the ED was tetanus toxoid with non-steroidal anti-inflammatory drugs being the most prescribed medication on discharge. blood tests were obtained in seven patients. Imaging was done in 19 patients and X-ray was the most commonly ordered modality. All patients were discharged home on their first visit. six of the patients re-attended the ED for different reasons. Male adults were the most affected victims by marine envenomations in Oman. sea urchins accounted for most envenomations. None of the patients developed life-threatening symptoms.
{"title":"Abstracts of 2022 Middle East and North Africa Toxicology Association (MENATOX) Conference (11–14 May 2022, Muscat, Oman)","authors":"Abdulmajeed Al-Qutaiti, A. Al-Kashmiri, Amina Al rawahi, A. Abri","doi":"10.1080/24734306.2022.2143697","DOIUrl":"https://doi.org/10.1080/24734306.2022.2143697","url":null,"abstract":"Injuries by marine creatures are a common presentation to Oman’s emergency departments (EDs). However, despite the difference in the marine fauna globally, there is no study on marine envenomation in Oman. We conducted a retrospective chart review of marine envenomation cases that presented to the ED at Khoula hospital, one of the main tertiary hospitals in Oman, between 2018 and 2019. We included patients of all ages who presented with injury secondary to contact with a marine creature. Multiple parameters were recorded, including causative creatures, symptoms, and medications. A total of 78 cases were included in this study, the majority (67.9%) were adults (18–64 years), and 82.1% were males. sea urchins accounted for most envenomations (52.6%). the pain was the most common presenting symptom (65.4%). the most common medication received in the ED was tetanus toxoid with non-steroidal anti-inflammatory drugs being the most prescribed medication on discharge. blood tests were obtained in seven patients. Imaging was done in 19 patients and X-ray was the most commonly ordered modality. All patients were discharged home on their first visit. six of the patients re-attended the ED for different reasons. Male adults were the most affected victims by marine envenomations in Oman. sea urchins accounted for most envenomations. None of the patients developed life-threatening symptoms.","PeriodicalId":23139,"journal":{"name":"Toxicology communications","volume":"90 1","pages":"120 - 129"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82084673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-31DOI: 10.1080/24734306.2022.2077584
Sarah G. Mahonski, S. Mohan, M. Howland, R. Biary
Abstract Glycopyrronium is an antimuscarinic drug that is available in a moist towelette preparation for the treatment of primary axillary hyperhidrosis, which is characterized by excessive sweating on the palms, soles of feet, and axillary region. Antimuscarinic toxicity is uncommon with therapeutic use. A 25-year-old female presented to the emergency department with urinary retention and visual changes after initiating topical glycopyrronium tosylate therapeutically. She was tachycardic with a heart rate of 115 beats/min and required a Foley catheter for urinary retention of over 1200 mL. She received 1.5 mg physostigmine for antimuscarinic symptoms and her heart rate improved. Despite treatment, she required a Foley catheter for four days with eventual improvement. This case demonstrates side effects of an unusual preparation of glycopyrronium and the need to take a detailed topical medication history in patients with antimuscarinic symptoms.
{"title":"Antimuscarinic toxicity secondary to moist towelettes containing glycopyrronium tosylate: a case report","authors":"Sarah G. Mahonski, S. Mohan, M. Howland, R. Biary","doi":"10.1080/24734306.2022.2077584","DOIUrl":"https://doi.org/10.1080/24734306.2022.2077584","url":null,"abstract":"Abstract Glycopyrronium is an antimuscarinic drug that is available in a moist towelette preparation for the treatment of primary axillary hyperhidrosis, which is characterized by excessive sweating on the palms, soles of feet, and axillary region. Antimuscarinic toxicity is uncommon with therapeutic use. A 25-year-old female presented to the emergency department with urinary retention and visual changes after initiating topical glycopyrronium tosylate therapeutically. She was tachycardic with a heart rate of 115 beats/min and required a Foley catheter for urinary retention of over 1200 mL. She received 1.5 mg physostigmine for antimuscarinic symptoms and her heart rate improved. Despite treatment, she required a Foley catheter for four days with eventual improvement. This case demonstrates side effects of an unusual preparation of glycopyrronium and the need to take a detailed topical medication history in patients with antimuscarinic symptoms.","PeriodicalId":23139,"journal":{"name":"Toxicology communications","volume":"11 1","pages":"71 - 73"},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74281498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-28DOI: 10.1080/24734306.2022.2137922
Kyle Suen, Andres Guzman Soto, Daniel Nogee, Patricia A. Filkins, Connor Walsh, J. Carpenter
{"title":"Compliance to whole bowel irrigation recommendations: a single poison center study","authors":"Kyle Suen, Andres Guzman Soto, Daniel Nogee, Patricia A. Filkins, Connor Walsh, J. Carpenter","doi":"10.1080/24734306.2022.2137922","DOIUrl":"https://doi.org/10.1080/24734306.2022.2137922","url":null,"abstract":"","PeriodicalId":23139,"journal":{"name":"Toxicology communications","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87014789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-26DOI: 10.1080/24734306.2022.2118475
A 19-year-old male prisoner attended a medical appointment, during which he was observed inhaling or ingesting a clear liquid. Following this, he became agitated, requiring mechanical and chemical restraint. Extreme agitation persisted despite intramuscular midazolam (10 mg). On arrival to ED he appeared flushed with dry skin, mydriasis, severe tachycardia (130 bpm), and hypertension (180/110 mmHg). He was subsequently intubated for agitation and behavioural control. His admission was complicated by mild rhabdomyolysis and five generalised tonic-clonic seizures over 2 d, with persistent mydriasis and sinus tachycardia. Peak temperature was 39 °C. The Victorian Poisons Information Centre was contacted. Given the limited exposure history, ongoing seizure activity, and general anaesthetic control of agitation, physostigmine was not recommended despite evidence of a possible anticholinergic toxidrome. The patient was extubated uneventfully on day three and made a full recovery. Total length of hospital stay was 67 h, Intensive Care Unit length of stay was 44 h. Whole blood was analysed for atropine using high-performance liquid chromatography with tandem mass spectrometry. Atropine concentration was 0.01 mg/L (10 ng/mL). This sample was analysed as part of the Emerging Drugs of Australia VIC project – a Health. vic supported, multi-institutional initiative providing intelligence on Victorian ED illicit drug presentations.
{"title":"Proceedings of the toxicology and Poisons Network Australasia (TAPNA) 2022 Annual Scientific Meeting","authors":"","doi":"10.1080/24734306.2022.2118475","DOIUrl":"https://doi.org/10.1080/24734306.2022.2118475","url":null,"abstract":"A 19-year-old male prisoner attended a medical appointment, during which he was observed inhaling or ingesting a clear liquid. Following this, he became agitated, requiring mechanical and chemical restraint. Extreme agitation persisted despite intramuscular midazolam (10 mg). On arrival to ED he appeared flushed with dry skin, mydriasis, severe tachycardia (130 bpm), and hypertension (180/110 mmHg). He was subsequently intubated for agitation and behavioural control. His admission was complicated by mild rhabdomyolysis and five generalised tonic-clonic seizures over 2 d, with persistent mydriasis and sinus tachycardia. Peak temperature was 39 °C. The Victorian Poisons Information Centre was contacted. Given the limited exposure history, ongoing seizure activity, and general anaesthetic control of agitation, physostigmine was not recommended despite evidence of a possible anticholinergic toxidrome. The patient was extubated uneventfully on day three and made a full recovery. Total length of hospital stay was 67 h, Intensive Care Unit length of stay was 44 h. Whole blood was analysed for atropine using high-performance liquid chromatography with tandem mass spectrometry. Atropine concentration was 0.01 mg/L (10 ng/mL). This sample was analysed as part of the Emerging Drugs of Australia VIC project – a Health. vic supported, multi-institutional initiative providing intelligence on Victorian ED illicit drug presentations.","PeriodicalId":23139,"journal":{"name":"Toxicology communications","volume":"71 1","pages":"101 - 119"},"PeriodicalIF":0.0,"publicationDate":"2022-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90730389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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