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Wegener’s Granulomatosis presenting with multiple cranial neuropathies. 韦格纳肉芽肿病表现为多发性颅神经病变。
Pub Date : 2008-12-31 DOI: 10.5580/263e
M. Lowden, Aiesha Ahmed
A 41 �year-old man had headaches, hearing loss, and left facial palsy for five months. Examination was remarkable for left seventh nerve palsy, left sided hearing loss and hemi tongue atrophy. MRI showed left cerebellopontine angle dural thickening.(Figure1and 2). Laboratory studies (CSF and blood) were unremarkable for an infectious, neoplastic and autoimmune etiology except for an elevated Antineutrophil cytoplasmic antibody titer. A dural biopsy showed chronic inflammation with granuloma formation. He was started on prednisone with plans to start immunosuppresants as outpatient.
一名41岁的男性患有头痛、听力丧失和面部麻痹5个月。左侧第七神经麻痹、左侧听力丧失、半舌萎缩等表现显著。MRI显示左脑桥小脑角硬脑膜增厚。(图1和图2)。除了抗中性粒细胞细胞质抗体滴度升高外,实验室研究(脑脊液和血液)对感染性、肿瘤性和自身免疫性病因无明显影响。硬脑膜活检显示慢性炎症伴肉芽肿形成。他开始服用强的松,并计划在门诊开始使用免疫抑制剂。
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引用次数: 0
Pseudo Todd’s palsy in a patient with medically intractable epilepsy
Pub Date : 2008-12-31 DOI: 10.5580/1942
N. Sethi, D. Labar, J. Torgovnick, P. Sethi, E. Arsura, T. Barliya, A. Wasterlain
Patients with epilepsy may also have non-epileptic seizures (pseudo seizures). One study showed that 1 out of 5 people presenting to a comprehensive epilepsy center with the diagnosis of medically intractable epilepsy actually had non-epileptic events when monitored. It is particularly difficult to diagnose non-epileptic seizures in patients who also suffer from real epileptic seizures. Various non-epileptic clinical presentations have been reported in the literature. Patients may present with predominantly non-epileptic convulsions characterized by out of phase thrashing movements of the limbs, pelvic thrusting and side to side movements of the head. At other times the non-epileptic manifestations are predominantly psychiatric in character with patients exhibiting bizarre behavior, reporting vivid visual and somatosensory hallucinations or directed vocalizations. We present here a patient with medically intractable epilepsy who presented with dense hemiplegia and hemisensory loss after reported seizures at home. Patient was considered an ideal candidate for intravenous tissue plasminogen activator (tPA) therapy so an acute stroke up was initiated at the time of presentation to the ER. CT scan and MRI brain with DWI was negative for acute stroke. Neurological examination was suggestive of psychogenic weakness. Patient made a full recovery over a course of 2 days. Pseudoparalysis or pseudo Todd’s palsy should be considered in the differential of a patient with epilepsy presenting with acute hemiplegia and other focal neurological deficits especially if they are young and lack traditional vascular risk factors for stroke.
癫痫患者也可能有非癫痫性发作(假性发作)。一项研究表明,在综合癫痫中心诊断为医学上难治性癫痫的患者中,有五分之一的人在监测时实际上发生了非癫痫事件。对于患有真正癫痫发作的患者,诊断非癫痫性发作尤为困难。各种非癫痫的临床表现已在文献中报道。患者可能主要表现为非癫痫性抽搐,其特征是肢体的非相抖动运动,骨盆刺痛和头部的左右运动。在其他时候,非癫痫表现主要是精神病学特征,患者表现出奇怪的行为,报告生动的视觉和体感幻觉或定向发声。我们在这里提出一个病人难治性癫痫谁提出了密集偏瘫和半感觉丧失后报告癫痫发作在家里。患者被认为是静脉注射组织型纤溶酶原激活剂(tPA)治疗的理想人选,因此在急诊室就诊时开始急性中风。急性脑卒中CT、MRI及DWI均为阴性。神经学检查提示心因性虚弱。病人在两天内就完全康复了。在鉴别伴有急性偏瘫和其他局灶性神经功能缺损的癫痫患者时,应考虑假性麻痹或假性托德麻痹,特别是如果患者年轻且缺乏中风的传统血管危险因素。
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引用次数: 1
Cryptococcal Meningitis in a Patient with Idiopathic CD4+ T-lymphocytopenia.A case report 特发性CD4+ t淋巴细胞减少患者的隐球菌性脑膜炎。病例报告
Pub Date : 2008-12-31 DOI: 10.5580/458
N. Gomes, F. Gomes
A case is presented of a 66 year old lady with long standing lymphocytopenia who developed the sudden onset of inability to walk. She was subsequently diagnosed with both cryptococcal meningitis and idiopathic CD4+ T-lymphocytopenia. This report highlights important points regarding these diagnoses and their association.
一个病例是提出了66岁的妇女与长期淋巴细胞减少谁发展的突然发作无法行走。她随后被诊断为隐球菌性脑膜炎和特发性CD4+ t淋巴细胞减少症。本报告强调了这些诊断及其相关性的要点。
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引用次数: 0
Limb-Shaking Transient Ischemic Attacks: Diagnosis, Prognosis, and Management 摇晃肢体的短暂性脑缺血发作:诊断、预后和管理
Pub Date : 2008-12-31 DOI: 10.5580/15bb
D. Pérez, L. Elijovich
Limb-shaking transient ischemic attacks (LSTIAs) are a rare manifestation of carotid occlusive disease. We report the case of an 81 year old woman who presented with recurrent LSTIAs and received conservative treatment with cessation of her antihypertensive medications. Multi-Slice Detector CT Angiography (MSCTA) demonstrated a right internal carotid artery occlusion with evidence of cerebral autoregulatory compensation via leptomeningeal vessels. This case characterizes LSTIAs and demonstrates the use of MSCTA in diagnosis, prognosis, and management.
肢体抖动短暂性脑缺血发作(LSTIAs)是颈动脉闭塞性疾病的一种罕见表现。我们报告一例81岁女性复发性lstia并接受保守治疗并停止抗高血压药物。多层螺旋CT血管造影(MSCTA)显示右侧颈内动脉闭塞,并通过小脑膜血管显示大脑自我调节代偿。该病例具有lstia的特征,并证明了MSCTA在诊断、预后和治疗中的应用。
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引用次数: 0
Acute Hydrocephalus: Unsual Presentation of Neurosarcoidosis 急性脑积水:神经结节病的不寻常表现
Pub Date : 2008-12-31 DOI: 10.5580/1a45
S. Dewani, V. Wood, S. Srivastava
Objective: We report a case of hydrocephalus as manifestation of neurosarcoidosis in absence of pulmonary features. The diagnosis and management could be a challenge in such atypical presentation of hydrocephalus in previously healthy young adult. The goal is to emphasize on importance to recognize atypical presentation in timely manner as neurologic involvement is significant cause of mortality and morbidity.
目的:我们报告一例脑积水表现为神经结节病,但没有肺部特征。诊断和管理可能是一个挑战,在这种不典型的表现脑积水在以前健康的年轻人。目的是强调及时识别非典型表现的重要性,因为神经系统受累是死亡率和发病率的重要原因。
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引用次数: 0
CNS demyelination after treatment with bupropion 安非他酮治疗后中枢神经系统脱髓鞘
Pub Date : 2008-12-31 DOI: 10.5580/dc6
J. Burge, J. Ball, J. Chataway
We present a case of presumed inflammatory central nervous system demyelination in association with the use of bupropion for smoking cessation. The patient developed paraesesthesia and Lhermitte's phenomenon shortly after starting the drug. There were oligoclonal bands in cerebrospinal fluid and white matter lesions in the cerebral hemispheres and cervical spinal cord. The case is discussed in the light of the known side effects of the drug.
我们提出一个病例推定炎性中枢神经系统脱髓鞘与使用安非他酮戒烟有关。患者在开始服药后不久就出现了感觉异常和艾尔米特现象。脑脊液和脑半球及颈脊髓白质病变可见寡克隆条带。根据这种药物已知的副作用来讨论这个病例。
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引用次数: 0
Iopamidol Myelography Induced Status Epilepticus Iopamidol脊髓造影诱导癫痫持续状态
Pub Date : 2008-12-31 DOI: 10.5580/1a64
H. Dib, K. Ağan, I. Midi, Canan Aykut‐Bingol
A forty-eight year old woman presented with convulsive status epilepticus and respiratory arrest 45 minutes after a lumbar myelogram with iopamidol. Status epilepticus in epileptic patients are very rare complication after myelography with iopamidol and to our knowledge status epilepticus in non epileptic patients have been previously reported only in one patient. Although it is a rare complication, physicians should be aware of this potential complication, myelogram should be performed in a full organized hospital. It will be better to observe patients carefully after the procedure.
一位48岁的女性在使用iopamidol进行腰椎骨髓造影45分钟后表现为惊厥性癫痫持续状态和呼吸停止。癫痫患者的癫痫持续状态是非常罕见的并发症后,脊髓造影iopamidol和我们所知的非癫痫患者的癫痫持续状态以前只报道过一个病人。虽然这是一种罕见的并发症,但医生应该意识到这种潜在的并发症,骨髓造影应该在正规医院进行。术后最好仔细观察患者。
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引用次数: 0
An unusual clinical presentation of ischemic stroke due to carotid dissection: The wrist drop 颈动脉夹层引起的缺血性中风的一种不寻常的临床表现:手腕下垂
Pub Date : 2008-12-31 DOI: 10.5580/377
A. Pikula, J. Romero, C. Kase
We report a patient with sudden onset of right wrist drop mimicking radial nerve palsy, found to be due to a borderzone infarct due to spontaneous carotid artery dissection (CAD).
我们报告一个病人突然发作的右手腕下垂模仿桡神经麻痹,发现是由于自发性颈动脉夹层(CAD)引起的交界区梗死。
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引用次数: 7
Intracranial Lipomas; Radiographic and Clinical Characteristics. 颅内脂肪瘤;影像学和临床特征。
Pub Date : 2008-12-31 DOI: 10.5580/1665
A. Zamora, J. Asconapé
Intracranial lipomas (ICLs) are rare intracranial lesions. They represent a group of congenital malformations of the brain parenchyma, located more frequently in the pericallosal cistern and associated with other parenchymal or brain vascular malformations in up to half of cases.
摘要颅内脂肪瘤是一种罕见的颅内病变。它们代表了一组先天性脑实质畸形,更常位于胼胝体周围池,并在多达一半的病例中与其他脑实质或脑血管畸形有关。
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引用次数: 5
The Classical Type of Foix-Chavany-Marie Syndrome: Assessment and Treatment of Dysphagia 经典型Foix-Chavany-Marie综合征:吞咽困难的评估与治疗
Pub Date : 2008-12-31 DOI: 10.5580/184a
I. Chernev, R. Petrea, M. Reynolds, Feng Wang
Foix-Chavany-Marie syndrome (FCMS) or anterior opercular syndrome is a rare neurological syndrome most commonly caused by cerebrovascular accident. The anatomical substrate of the classical (clinical type A) FCMS is constituted by any combination of bilateral cortical (opercular) or subcortical (subopercular) lesion, typically as a result of subsequent strokes. FCMS is characterized by facio-labio-pharyngo-glosso-masticatory paralysis with automatic-voluntary dissociation where involuntary movements of the affected muscles are preserved. A 79 year old woman with FCMS is presented to discuss the assessment,
Foix-Chavany-Marie综合征(FCMS)是一种罕见的神经系统综合征,多由脑血管意外引起。经典(临床A型)FCMS的解剖基础由双侧皮质(眼)或皮质下(眼下)病变的任意组合构成,通常是随后中风的结果。FCMS的特点是面-唇-咽-舌-咀嚼麻痹伴自动-随意分离,其中受影响肌肉的不随意运动被保留。本文介绍一名患有FCMS的79岁女性,讨论评估。
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引用次数: 8
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The Internet Journal of Neurology
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