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Assessments and Treatment of Gunshot Injuries to the Penis 阴茎枪伤的评估与治疗
IF 0.5 Q4 EMERGENCY MEDICINE Pub Date : 2021-04-01 DOI: 10.30491/TM.2021.215811.1058
Mousa Asadi, Hasan Goodarzi, Sadrollah Mahmoodi
Background: Gunshot wound injuries to penile are relatively infrequent. Objectives: This study aimed at reviewing the patterns of gunshot injuries to the penile and their treatments. Methods: In November 2019, PubMed (MEDLINE), Scopus, Embase, ISI web of sciences and Google Scholar databases were searched for finding relevant studies. For this reason, various meshes and keywords were used to search including wound/injury, genitalia/genitourinary, Gunshot/war/explosion/firearm/military, penile/penis, scrotum, and urethral. Results: Of the five included studies, three studies were related to civilian gunshot injuries and two studies were related to war-injury. The average age of patients was in the range of 28-31 years old. The major gunshot penile injuries were Corporotomy, Corpus cavernosum, superficial penile wounds, and urethral injury. The most frequent concomitant damages were injuries to adjacent anatomies, including thigh injury, scrotal/testicular, abdominal organs, bladder, and rectum. There are several surgical procedures depending on the degree of gunshot penile injuries such as surgical exploration, closing the residual penile stump of a partly amputated penis, penile degloving, penoscrotal approach, simple suturing, hemostatic suturing of Buck’s fascia and skin, and surgical re-anastomosis or total replacement with phallic reconstruction. Conclusion: Penile gunshot injuries often are concomitant with other severe injuries in adjacent anatomies, which have a negative impact on the mortality of victims. For the management of these cases, it is essential to evaluate the length and size of and type of weapons.
背景:阴茎枪伤相对少见。目的:本研究旨在回顾阴茎枪伤的类型及其治疗。方法:于2019年11月检索PubMed (MEDLINE)、Scopus、Embase、ISI web of sciences和Google Scholar数据库查找相关研究。为此,我们使用了各种网格和关键词进行搜索,包括伤口/损伤、生殖器/泌尿生殖系统、枪击/战争/爆炸/火器/军事、阴茎/阴茎、阴囊和尿道。结果:在纳入的五项研究中,三项研究与平民枪伤有关,两项研究与战争伤害有关。患者平均年龄28 ~ 31岁。枪弹性阴茎损伤以阴茎切开术、阴茎海绵体伤、阴茎浅表伤和尿道伤为主。最常见的伴随损伤是相邻解剖的损伤,包括大腿损伤、阴囊/睾丸、腹部器官、膀胱和直肠。根据阴茎枪伤的程度,有几种手术方法,如手术探查、关闭部分切除的阴茎残端、阴茎脱套、阴茎阴囊入路、简单缝合、止血缝合巴克氏筋膜和皮肤、手术再吻合或阴茎重建全置换。结论:阴茎枪弹损伤常伴有邻近解剖的其他严重损伤,对受害者的死亡率有不利影响。为了处理这些案件,必须评估武器的长度、大小和类型。
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引用次数: 0
Effect of Dexmedetomidine on Blood Pressure in Hypertension Patients after Emergency Laparotomy for Trauma: A Randomized Double-blind Clinical Trial 右美托咪定对创伤急诊剖腹手术高血压患者血压的影响:一项随机双盲临床试验
IF 0.5 Q4 EMERGENCY MEDICINE Pub Date : 2021-04-01 DOI: 10.30491/TM.2021.274843.1249
R. M. Gargari, H. Anvari
Background: Patients with a history of hypertension experience higher postoperative complications than healthy individuals. The frequency of such complications is also higher in emergency patients than elective ones; therefore, it seems that preventive measures are essential. Objectives: The present study aimed at determining the effect of dexmedetomidine on blood pressure in patients with hypertension after emergency laparotomy for trauma. Methods: The present study was a randomized, double-blind clinical trial performed from 2019 to 2020 on patients with a history of hypertension undergoing emergency laparotomy. Patients received the intervention 15 minutes before surgery (the intervention group: intravenous (iv) dexmedetomidine and the control group: normal saline), and the intensity of the pain(VAS), agitation(RASS), and blood pressure were measured and compared at different time points. Data were compared using SPSS software (version 21) by t-test and Chi-square tests considering a significance level of <0.05. Results: There were statistically significant differences between the two groups just after the drug infusion and at all studied time points (p <0.05), so that the intervention group had more stable blood pressure. Pain intensity (p <0.05) and the degree of agitation (p <0.05) in the intervention group were significantly lower than that in the control group at all studied time points. Conclusion: Dexmedetomidine infusion leads to a stabilization of blood pressure during surgery and after surgery, pain relief, and agitation in patients with hypertension undergoing emergency laparotomy for trauma.
背景:有高血压病史的患者比健康人有更高的术后并发症。急诊患者出现此类并发症的频率也高于非急诊患者;因此,预防措施似乎是必不可少的。目的:本研究旨在确定右美托咪定对创伤急诊剖腹手术后高血压患者血压的影响。方法:本研究是一项随机双盲临床试验,于2019 - 2020年对有高血压病史的患者进行急诊剖腹手术。患者在手术前15分钟接受干预(干预组:静脉注射右美托咪定,对照组:生理盐水),测量并比较不同时间点的疼痛强度(VAS)、躁动程度(RASS)和血压。数据比较采用SPSS软件(版本21),采用t检验和卡方检验,考虑显著性水平<0.05。结果:两组在药物输注后及各研究时间点血压差异均有统计学意义(p <0.05),干预组血压更稳定。干预组疼痛强度(p <0.05)、躁动程度(p <0.05)在各研究时间点均显著低于对照组。结论:右美托咪定输注可使急诊开腹手术的高血压患者术中及术后血压稳定,疼痛减轻,烦躁不安。
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引用次数: 0
Pattern of Injury and Outcome of Victims in Ahvaz Terrorist Attack 阿瓦士恐怖袭击中受害者的伤害模式和结果
IF 0.5 Q4 EMERGENCY MEDICINE Pub Date : 2021-04-01 DOI: 10.30491/TM.2021.227086.1098
H. Araghizadeh, H. Khoshmohabat, S. H. Hossini, M. Moayed
Background: Responses for medical emergencies can be different during most terrorist attacks in which civilians and military personnel might be killed or wounded. Objectives: The present study aimed to reflect on injury patterns and the outcome of victims in terrorist attacks. Methods: A retrospective research design study was conducted on the data obtained from terrorist attacks in the city of Ahvaz, Iran, on September 22, 2018. In this deadly incident, 92 military and civilian victims had been transferred to hospitals within the first 24 hours. To this end, the data including age, gender, causes, site of injuries, outcomes, and the Injury Severity Score (ISS) values were analyzed.  Data were acquired from the Iranian Legal Medicine Organization, the Iranian Emergency Department, as well as health care facilities. Results: The findings revealed that, out of 92 victims of Ahvaz terrorist attack, 85 cases (92.4%) were men. The mean age of these individuals was about 28.68±11.22 years and 41.3% of them were in need of urgent surgical interventions. There was no information regarding casualties in 22.3% of the cases. Moreover, 25% of the causalities had led to death. The mean of ISS was 8.19±13. Besides, there was a significant relationship between ISS values and patient outcomes (p <0.0001). A relationship was also observed between multiple injuries and mortality rates although it did not include main body parts. Conclusion: The results showed that the mortality rate of casualties in the Ahvaz terrorist attack was high. With respect to the findings, extensive actions are needed to maintain the readiness of the emergency medical care services and to manage such events.
背景:在大多数可能造成平民和军事人员伤亡的恐怖袭击中,对医疗紧急情况的反应可能有所不同。目的:本研究旨在反映恐怖袭击中受害者的伤害模式和结果。方法:对2018年9月22日发生在伊朗阿瓦士市的恐怖袭击事件数据进行回顾性研究设计。在这一致命事件中,92名军人和平民受害者在最初24小时内被转移到医院。为此,我们分析了包括年龄、性别、原因、损伤部位、结果和损伤严重程度评分(ISS)值在内的数据。数据是从伊朗法律医学组织、伊朗急诊科以及保健设施获得的。结果:调查结果显示,在阿瓦士恐怖袭击的92名受害者中,男性85例,占92.4%。这些患者的平均年龄为28.68±11.22岁,其中41.3%的患者需要紧急手术治疗。22.3%的病例无伤亡信息。此外,25%的伤亡导致死亡。平均ISS为8.19±13。此外,ISS值与患者预后之间存在显著相关(p <0.0001)。还观察到多处受伤与死亡率之间的关系,尽管不包括主要身体部位。结论:结果表明,阿瓦士恐怖袭击中伤亡人员的死亡率很高。关于调查结果,需要采取广泛行动,以保持紧急医疗服务的准备状态,并管理这类事件。
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引用次数: 0
Comparative Evaluation of Various Methods of Drainage of the Abdominal Cavity in Patients with Secondary Bacterial Peritonitis 继发性细菌性腹膜炎不同腹腔引流方法的比较评价
IF 0.5 Q4 EMERGENCY MEDICINE Pub Date : 2021-04-01 DOI: 10.30491/TM.2021.281240.1278
M. I. Bokarev, A. I. Mamykin, Khaled J Alali, Andrey I Demyanov, E. Stolyarchuk, A. E. Markarov
Background: Secondary peritonitis is a serious complication of all the inflammatory diseases and injuries of the abdominal organs and requires urgent surgical intervention. The mortality rate of patients with secondary bacterial peritonitis (SBP) reaches 70%. In some patients, despite the treatment, secondary peritonitis turns into tertiary peritonitis (TP), which complicates the healing process and aggravates the prognosis. Inadequate drainage of the abdominal cavity is a possible contributing factor to the formation of TP. Aims: A prospective study of the result of surgical treatment of patients with SBP was carried out to improve the results of treatment. Methods. The study included 608 patients with SBP who underwent surgery in a clinical hospital in Russia in 2013-2019. All the patients were divided into groups depending on the method of draining the abdominal cavity and on signs of the purulent process generalization, the marker of which was multiple organ failure. Efficiency of abdominal drainage (by the incidence of TP) and of treatment results (in terms of mortality) were assessed in each group. Results: In patients without signs of the purulent process generalization, drainage of the abdominal cavity with drainage tubes (293 observations) is accompanied by the development of TP in 4.1% of cases and by mortality in 22.9%. If the purulent process is of a generalized nature (315 observations), the incidence of TP increases ten-fold and is 41.9%, and the mortality rate increases 2.7 times and reaches 62.8%. With the generalization of the purulent process, the efficiency of drainage of the abdominal cavity has a significant impact on the results of surgical treatment of patients with SBP. If abdominal drainage is carried out with drainage tubes (129 observations), the incidence of TP is 41.9%, and the mortality rate is 62.8%. Drainage of the abdominal cavity using traditional laparostomy (Bogota bag, 104 cases) is accompanied by the development of TP in 36.5% of cases and mortality in 45.2%. If the abdomen is drained using active laparostomy (VAC-system, 82 observations), the incidence of TP is reduced to 18.3% and mortality to 19.5%. Conclusion. Drainage of the abdominal cavity is the most important stage of surgical intervention in patients with SBP. In cases of the purulent process generalization, drainage of the abdominal cavity in the most effective way– by active laparostomy (VAC-system) will improve the results of treatment of these patients.
背景:继发性腹膜炎是所有炎性疾病和腹部器官损伤的严重并发症,需要紧急手术干预。继发性细菌性腹膜炎(SBP)患者死亡率高达70%。在一些患者中,尽管进行了治疗,继发性腹膜炎仍会转变为三期腹膜炎(TP),使愈合过程复杂化,并使预后恶化。腹腔引流不足可能是导致TP形成的一个因素。目的:对收缩压患者的手术治疗效果进行前瞻性研究,以提高治疗效果。方法。该研究包括2013-2019年在俄罗斯一家临床医院接受手术的608名收缩压患者。所有患者根据腹腔引流方式和化脓过程的表现进行分组,以多脏器功能衰竭为标志。评估各组腹腔引流效率(以TP发生率衡量)和治疗效果(以死亡率衡量)。结果:在无化脓性过程征象的患者中,腹腔引流管引流(293例)伴TP发生的病例占4.1%,伴TP死亡的病例占22.9%。如果化脓过程具有广泛性(315次观察),TP的发病率增加10倍,达到41.9%,死亡率增加2.7倍,达到62.8%。随着化脓过程的普遍化,腹腔引流的效率对收缩压患者的手术治疗效果有重要影响。采用引流管进行腹腔引流(129例),TP发生率为41.9%,死亡率为62.8%。采用传统剖腹造口术(Bogota bag, 104例)引流腹腔,并发TP的病例占36.5%,死亡率为45.2%。如果使用主动开腹术(vac系统,82例观察)引流腹部,TP的发生率降低到18.3%,死亡率降低到19.5%。结论。腹腔引流是收缩压患者手术干预的最重要阶段。在脓性过程普遍化的情况下,最有效的腹腔引流方式-主动开腹术(vac系统)将改善这些患者的治疗结果。
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引用次数: 0
Surgical Outcomes of Perilunate Dislocations and Perilunate Fracture-dislocations: A Review of 20 Cases 20例月骨周围脱位和月骨周围骨折脱位的手术疗效分析
IF 0.5 Q4 EMERGENCY MEDICINE Pub Date : 2021-04-01 DOI: 10.30491/TM.2021.237623.1140
Mehran Razavipour, S. Ghaffari, Alireza Kazemi, M. Azar
Background: Perilunate dislocations and perilunate fracture-dislocations (PLD/PLFD) are the second most common wrist injuries. Objectives: Given the limited available case series due to the rarity of these injuries, in this study, we report the functional outcomes of 20 patients who received surgical treatment with a mean follow-up of 28 months (range 24-36). Methods: We retrospectively reviewed the admissions to Imam Khomeini Hospital Sari, Iran, and included patients with (PLD/PLFD) who underwent surgical treatment between January 2014 to December 2019. We included 20 patients (16 males, mean age±SD=33.6±12.4) who had received urgent surgical treatment following the initial closed reduction in the emergency department. All of the patients received surgical treatment from the same surgical team using the dorsal approach. Results: We observed the average Mayo Wrist Score (MWS) of 73.8±8.4 (range 65-100) with excellent or good outcomes in 40% of patients. The MWS was slightly higher in patients with the non-dominant injured side, yet it did not significantly differ with those with a dominant hand injury (75.4±9.6 vs. 71.2±5.8, P=0.29). Furthermore, we did not find a significant difference in MWS between the lesser and greater arc injuries (76.5±10.1 vs. 71.1±5.7, P=0.15). The observed flexion and extension ROM were significantly lower than the contralateral side (p <0.001). Similar patterns of lower grip and pinch strength were observed on the injured side, which was significantly lower than the contralateral hand; 38.4±8.6 (74±14% of the contralateral) and 9.9±2.4 (81±15% of the contralateral), respectively (p <0.001). Conclusion: In line with other cohorts, the present case series demonstrates relatively good functional postoperative outcomes in PLD/PLFD. Our findings are comparable with prior reports concerning reasonably satisfactory MWS, ROM relative to the contralateral side and reported occasional mild pain with activity. Future studies should be directed to investigate long-term complications associated with these injuries, particularly the development of wrist osteoarthritis.
背景:月骨周围脱位和月骨周围骨折脱位(PLD/PLFD)是第二常见的手腕损伤。目的:由于这些损伤的罕见性,可用的病例系列有限,在本研究中,我们报告了20例接受手术治疗的患者的功能结局,平均随访28个月(范围24-36)。方法:我们回顾性分析了2014年1月至2019年12月在伊朗萨里伊玛目霍梅尼医院(Imam Khomeini Hospital Sari)接受手术治疗的PLD/PLFD患者。我们纳入20例患者(男性16例,平均年龄±SD=33.6±12.4),他们在急诊科首次闭合复位后接受了紧急手术治疗。所有患者均由同一手术小组采用背侧入路进行手术治疗。结果:我们观察到平均梅奥手腕评分(MWS)为73.8±8.4(范围65-100),40%的患者预后优良或良好。非优势侧损伤患者的MWS略高于优势侧损伤患者(75.4±9.6比71.2±5.8,P=0.29)。此外,我们发现小弧线损伤和大弧线损伤的MWS没有显著差异(76.5±10.1比71.1±5.7,P=0.15)。观察到的屈伸ROM明显低于对侧(p <0.001)。在受伤一侧观察到类似的低握力和捏力模式,明显低于对侧手;对侧分别为38.4±8.6(74±14%)和9.9±2.4(81±15%)(p <0.001)。结论:与其他队列一样,本病例系列显示PLD/PLFD的术后功能预后相对较好。我们的研究结果与先前报道的相当满意的MWS,相对于对侧的ROM和偶尔轻度疼痛的报道相当。未来的研究应着眼于调查与这些损伤相关的长期并发症,特别是手腕骨关节炎的发展。
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引用次数: 1
Designing a Guideline for Emergency Medical Communication Center Staff to Help Road Traffic Crash Patients: A Delphi Study 设计急救医疗沟通中心人员协助道路交通事故患者的指引:德尔菲研究
IF 0.5 Q4 EMERGENCY MEDICINE Pub Date : 2021-01-01 DOI: 10.30491/TM.2021.250496.1177
Hojjat Shafaee, A. Ostadtaghizadeh, Davoud Khorasani-Zavareh, S. Nematollahi, J. Hirshon, A. Mirhaghi, M. Moradian
Background: Injuries and deaths from RTC are critical health problems of societies and one of the main causes of death especially among the young. Objective: This study aimed to design and compile a guideline for emergency medical communication centers (EMCC) staff to provide direct assistance offered by road traffic crash (RTC) bystanders. Methods: Based on prior literature, the RTC bystanders' initial draft guideline contained 20 domains and 28 items. As a validation step, the draft guideline was reviewed by content experts (one emergency medicine and two disaster specialists) and modified based on their recommendations. The subsequent draft guideline was then reviewed in three Delphi rounds by 67 participants, including health professionals in emergencies and disasters, emergency medicine, nurses, emergency medical experts, and EMCC staff. The accepted agreement coefficient was set at ≥70%. As the final step, an expert consensus meeting was held to review the guideline. Results: The participants agreed on 56 items regarding 20 domains, including scene safety, hand precautions, and personal protection, alertness assessment, respiration, cardiopulmonary resuscitation (CPR), bleeding control, recovery position, splinting, rapid evacuation, scene management, patient transfer, triage, spinal cord injury prevention and immobilization, injured transportation, psychological support, hypothermia prevention, water and food, amputated limb protection, and support of deceased people. Two items in relation to airway opening maneuvers were added to the guideline during the expert consensus meeting. Conclusion: Compared to other RTC bystander guidelines for EMCC staff, more comprehensive guidelines can be served as a basis for directing RTC bystanders to provide assistance. Important areas of hand care and personal protection, breathing, airway, splinting, scene management, mental and psychological support, and support of deceased people were included in this guideline. EMCC staff can provide guidance to be performed by RTC bystanders. RTC bystanders can play important roles at crash scenes, including preventing secondary injury, supporting scene management, and providing first aid for the injured people. This guideline can be used to help direct appropriate care and behavior by RTC bystanders.
背景:RTC造成的伤害和死亡是严重的社会健康问题,也是导致死亡的主要原因之一,尤其是在年轻人中。目的:本研究旨在设计并编制一份指引,供急救医疗通讯中心(EMCC)人员提供道路交通事故(RTC)旁观者的直接协助。方法:基于已有文献,RTC旁观者指南初稿包含20个领域28个条目。作为验证步骤,指南草案由内容专家(一名急诊医学专家和两名灾害专家)审查,并根据他们的建议进行修改。随后的准则草案随后由67名参与者进行了三轮德尔菲审查,其中包括紧急情况和灾害中的卫生专业人员、急诊医学、护士、急诊医学专家和EMCC工作人员。可接受的一致系数设为≥70%。作为最后一步,召开了一次专家共识会议来审查该指南。结果:与会者就现场安全、手部防护和个人防护、警备性评估、呼吸、心肺复苏(CPR)、出血控制、恢复体位、夹板、快速疏散、现场管理、患者转移、分诊、脊髓损伤预防和固定、伤者运输、心理支持、体温过低预防、水和食物、截肢保护、以及对逝者的支持。在专家共识会议期间,两项与气道开放操作有关的内容被添加到指南中。结论:与EMCC工作人员的RTC旁观者指南相比,更全面的指南可作为指导RTC旁观者提供帮助的依据。该指南包括手部护理和个人防护、呼吸、气道、夹板、现场管理、精神和心理支持以及对死者的支持等重要领域。EMCC工作人员可以为RTC旁观者提供指导。RTC旁观者可以在事故现场发挥重要作用,包括防止二次伤害,支持现场管理,并为受伤人员提供急救。本指南可用于指导RTC旁观者的适当护理和行为。
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引用次数: 0
Identifying Challenges of Providing Care for Trauma Patients; A Concurrent Mixed Methods Study 识别创伤患者护理的挑战并行混合方法研究
IF 0.5 Q4 EMERGENCY MEDICINE Pub Date : 2021-01-01 DOI: 10.30491/TM.2021.223980.1082
Zahra Jamshidi, K. Tabrizi, M. Fallahi-khoshknab, A. Dalvandi, F. Vizeshfar, H. Khankeh
Background: Caregiving for trauma patients has many challenges. Inadequate knowledge of these challenges can affect the patients and worsen their conditions. Objectives: We aimed to explore the caregivers’ experiences about these challenges and problems of caring for patients with trauma emergencies. Methods: The study adopted a concurrent triangulation mixed-method and was conducted in Shahid Rajaee Hospital, southern Iran, in 2019. Semi-structured interviews, focus groups, observation and ward document assessments were conducted with focusing on the challenges experienced by the caregivers. A checklist was used to assess the performance of caregivers and measure the indices related to the care process. Statistical results and qualitative data on the main categories were compared and integrated for data analysis. Results: In total,307 codes were extracted by analyzing the content of the interviews and available evidence. The codes were summarized in 20 subcategories, and six main categories were extracted as follows: lack of professional capability, uncoordinated team response, deficits in managerial commitments, inadequate work motivation, complex nature of trauma emergency, and lack of clinical communication. The quantitative results indicated that caregivers’ performance was considerably far from the expected scores and also many indices indicated a waste of time in responding to the patient needs. Conclusion: Various dimensions of trauma care challenges indicate that professional capability, team coordination and communication, managerial commitments and work motivation considering the complex nature of trauma emergency wards are crucial to enhance patients' access to optimum quality care. Caregivers’ performance and quality of indices also affect the care process. Future studies are required for compiling strategies and protocols for the quality of care for trauma patients.
背景:创伤患者的护理面临许多挑战。对这些挑战的认识不足可能会影响患者并使其病情恶化。目的:探讨护理人员在护理创伤急症患者时遇到的挑战和问题。方法:研究采用并行三角测量混合方法,于2019年在伊朗南部Shahid Rajaee医院进行。针对护理人员面临的挑战,进行了半结构化访谈、焦点小组、观察和病房文件评估。使用检查表来评估护理人员的表现,并测量与护理过程相关的指标。对主要类别的统计结果和定性数据进行比较和整合,以进行数据分析。结果:通过对访谈内容和现有证据的分析,共提取出307种编码。将其归纳为20个小类别,提炼出6个主要类别:专业能力不足、团队反应不协调、管理承诺缺失、工作动机不足、创伤急救性质复杂、缺乏临床沟通。定量结果表明,护理人员的表现与预期得分相差甚远,而且许多指标表明,在响应患者需求方面浪费了时间。结论:创伤护理挑战的不同维度表明,考虑到创伤急诊科的复杂性,专业能力、团队协调和沟通、管理承诺和工作动机是提高患者获得最佳质量护理的关键。护理人员的绩效和质量指标也会影响护理过程。未来的研究需要编制策略和方案,以提高创伤患者的护理质量。
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引用次数: 0
Effect of an Injury Prevention Program on Traumatic Factors and Athletic Performance in Judo Athletes: MSSLSTS Intervention 伤害预防项目对柔道运动员创伤因素和运动成绩的影响:MSSLSTS干预
IF 0.5 Q4 EMERGENCY MEDICINE Pub Date : 2021-01-01 DOI: 10.30491/TM.2021.214296.1045
M. Mahmoudkhani, A. Shakibaee, H. Minoonejad, R. Rajabi, A. Barati
Background: Judo as martial arts have a higher risk of trauma during training rather than competition. Thus, an efficient training procedure should be accomplished. Objectives: Since the use of trauma prohibition approaches and athletic performance enhancement is essential, this study aimed at investigating the effect of 8-week Judo Specific Functional Training (JSFT) on the Traumatic factors and athletic performance in male judokas. Methods: 46 subjects were randomly classified into 2 groups of experimental (N: 23) and control (N: 23) groups. For eight weeks, the experimental group attended a JSFT program designed by the researchers. The control group participated in the usual judo training program presented by the coaches. The exercises were accomplished 3 times per week for 90 minutes each session. The subjects participated in pre-and post-tests. In order to approve the data normality and compare the variables, Shapiro-Wilk, ANCOVA analysis was implemented at the significant level of p˂ 0.05 using SPSS (version 21). Results: The outcomes showed that the scores of functional movement screening (p=0.001), upper extremity Y balance test (p=0.001), vertical jump (p=0.001) and JSFT (p=0.001) significantly increased among the experimental group in comparison to the control group. Conclusions: The JSFT program simultaneously modifies or decreases the Traumatic factors and improves athletic performance and offers more efficiency and effectiveness rather than the usual judo training programs.
背景:柔道作为一种武术,在训练中比在比赛中有更高的创伤风险。因此,应该完成一个有效的培训程序。目的:由于使用创伤禁止方法和运动成绩的提高是必不可少的,本研究旨在探讨8周柔道特异性功能训练(JSFT)对男性柔道运动员创伤因素和运动成绩的影响。方法:将46例受试者随机分为试验组(N: 23)和对照组(N: 23)。在八周的时间里,实验组参加了由研究人员设计的JSFT项目。对照组则按照教练提供的常规柔道训练计划进行训练。这些练习每周进行3次,每次90分钟。受试者分别参加前、后测试。为了验证数据的正态性并比较变量,使用SPSS (version 21)在p小于0.05的显著水平上进行了Shapiro-Wilk, ANCOVA分析。结果:实验组的功能运动筛查(p=0.001)、上肢Y平衡测试(p=0.001)、垂直跳(p=0.001)和JSFT (p=0.001)得分均较对照组显著提高。结论:与普通柔道训练方案相比,JSFT方案可以同时改变或减少创伤因素,提高运动成绩,提供更高的效率和效果。
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引用次数: 1
Dense Bone-Derived 3d Bioscaffold: Preparation, Characterization, and Assessment of Its Potential for Bone Marrow Mesenchymal Stem Cells (BMSCS) Growth and Differentiation 致密骨来源的三维生物支架:制备、表征和评估其对骨髓间充质干细胞(BMSCS)生长和分化的潜力
IF 0.5 Q4 EMERGENCY MEDICINE Pub Date : 2021-01-01 DOI: 10.30491/TM.2021.214604.1049
Rozita Ghahremani, A. Asadi, S. Zahri
Background: Since bone defects can result in different disabilities, many efforts have been made to bone tissue engineering. In this case, scaffolds play an important role as a key element of tissue engineering in providing three-dimensional structure for cell growth in vitro Objective: The aim of the present study was to provide the three-dimensional biological bioscaffold from the bovine femur dense bone and investigate the possibility of its potential for application in tissue engineering as biological 3D ECM bioscaffold via mesenchymal stem cells seeding and differentiation toward bone tissue. Methods: For the preparation of bioscaffolds, after cutting bovine femur bone into small pieces, demineralization and decellularization were done. Bioscaffolds biocompatibility was evaluated using an MTT assay. The morphological and cell adhesion characteristics of Bone marrow mesenchymal stem cells (BMSCs) on the bioscaffolds were evaluated using Scanning Electron Microscopy (SEM) technique. Finally, the cells were treated with an osteogenic differentiation medium and then evaluated for differentiation. Results: Histological studies showed that the use of sodium dodecyl sulfate (2.5%) for 8 h eliminated the cells. Radiography and calcium oxalate test confirmed demineralization. MTT assay and SEM studies showed that the obtained bioscaffolds are biocompatible and could provide an optimum three-dimensional environment for cell adhesion and movement. Moreover, the Alizarin red staining showed a higher differentiation rate for BMSCs. Conclusion: In the present study, bone-derived 3D bioscaffold showed an important role in the growth and differentiation of BMSCs, due to the natural characteristics, cell adhesion properties, and potential to enhance differentiation toward bone tissue. It may have the potential for use as bioscaffold as supporting metrics for maintenance, growth in bone tissue engineering.
背景:由于骨缺损可导致不同程度的残疾,骨组织工程已成为人们研究的热点。在这种情况下,支架在为细胞体外生长提供三维结构方面发挥着重要的作用,是组织工程的关键要素。目的:本研究的目的是利用牛股骨致密骨提供三维生物支架,并通过间充质干细胞的种植和向骨组织分化,探讨其作为生物三维ECM生物支架在组织工程中的应用潜力。方法:将牛大腿骨切成小块后进行脱矿脱细胞制备生物支架。采用MTT法评价生物支架的生物相容性。采用扫描电镜(SEM)技术观察骨髓间充质干细胞(BMSCs)在生物支架上的形态和细胞粘附特性。最后,将细胞用成骨分化培养基处理,然后评估其分化情况。结果:组织学研究表明,使用十二烷基硫酸钠(2.5%)8 h可消除细胞。x光片和草酸钙试验证实脱矿。MTT实验和扫描电镜研究表明,所制备的生物支架具有良好的生物相容性,可为细胞粘附和运动提供最佳的三维环境。茜素红染色显示骨髓间充质干细胞分化率较高。结论:在本研究中,骨源性3D生物支架由于其天然特性、细胞粘附特性和向骨组织分化的潜力,在BMSCs的生长和分化中发挥了重要作用。它可能有潜力作为生物支架,作为骨组织工程中维持、生长的支持指标。
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引用次数: 0
Prophylactic Use of Tranexamic Acid on Blood Loss in Cesarean Delivery: A Randomized Controlled- Clinical Trial 氨甲环酸预防剖宫产出血:一项随机对照临床试验
IF 0.5 Q4 EMERGENCY MEDICINE Pub Date : 2021-01-01 DOI: 10.30491/TM.2021.219676.1073
E. Jafarbegloo, Faride Faridnya, R. Ahangari, A. Mohammadbeigi
Background: Post-partum haemorrhage (PPH) is a major cause of maternal mortality worldwide. Tranexamic acid, an anti-fibrinolytic agent, is a novel approach in an attempt to prevent this dreadful complication. Objective: This study aimed to evaluate the efficacy and safety of tranexamic acid in reducing blood loss during and after cesarean section (CS). Methods: In this prospective randomized placebo-controlled clinical trial, 50 pregnant women were randomized into two groups. In the study group, 25 women received tranexamic acid 10 minutes before CS, whereas in the control group 25 women received distilled water. Blood was collected during two periods. The first time was from placental delivery to the end of CS and the second was from the end of CS to 2 h postpartum. The volume of blood was measured and compared between the two groups. Results: Tranexamic acid significantly reduced the quantity of blood from the end of CS to 2 h postpartum, which was 65.15±31.97 mL and 101.14±44.94 mL in the study and control groups, respectively (P =0.002). It also significantly reduced the volume of total blood from placental delivery to 2 h postpartum, which was 616.32±176.87 mL and 731.45±178.79 mL in the study and control groups (P =0.028). Total blood loss in the study group was 18.7% less than the control group. No complications or side effects were reported in the groups. Conclusions: Tranexamic acid statistically reduces the volume of blood loss from placental delivery to 2 h postpartum and its use was not associated with any side effects or complications. Therefore, tranexamic acid can be used as a safe and effective approach to reducing bleeding resulting from CS.
背景:产后出血(PPH)是全世界孕产妇死亡的一个主要原因。氨甲环酸,一种抗纤溶剂,是一种尝试预防这种可怕并发症的新方法。目的:评价氨甲环酸减少剖宫产术中及术后出血量的疗效和安全性。方法:采用前瞻性随机安慰剂对照临床试验,将50例孕妇随机分为两组。在研究组中,25名妇女在CS前10分钟服用氨甲环酸,而在对照组中,25名妇女服用蒸馏水。血液采集分两期进行。第一次是从胎盘分娩到CS结束,第二次是从CS结束到产后2h。测量两组患者的血容量并进行比较。结果:氨甲环酸可显著降低CS结束至产后2 h的血流量,研究组为65.15±31.97 mL,对照组为101.14±44.94 mL (P =0.002)。研究组与对照组总血容量分别为616.32±176.87 mL和731.45±178.79 mL,差异有统计学意义(P =0.028)。研究组总失血量比对照组减少18.7%。两组均无并发症或副作用。结论:氨甲环酸在统计学上可减少胎盘分娩至产后2小时的失血量,其使用与任何副作用或并发症无关。因此,氨甲环酸可以作为一种安全有效的方法来减少CS引起的出血。
{"title":"Prophylactic Use of Tranexamic Acid on Blood Loss in Cesarean Delivery: A Randomized Controlled- Clinical Trial","authors":"E. Jafarbegloo, Faride Faridnya, R. Ahangari, A. Mohammadbeigi","doi":"10.30491/TM.2021.219676.1073","DOIUrl":"https://doi.org/10.30491/TM.2021.219676.1073","url":null,"abstract":"Background: Post-partum haemorrhage (PPH) is a major cause of maternal mortality worldwide. Tranexamic acid, an anti-fibrinolytic agent, is a novel approach in an attempt to prevent this dreadful complication. Objective: This study aimed to evaluate the efficacy and safety of tranexamic acid in reducing blood loss during and after cesarean section (CS). Methods: In this prospective randomized placebo-controlled clinical trial, 50 pregnant women were randomized into two groups. In the study group, 25 women received tranexamic acid 10 minutes before CS, whereas in the control group 25 women received distilled water. Blood was collected during two periods. The first time was from placental delivery to the end of CS and the second was from the end of CS to 2 h postpartum. The volume of blood was measured and compared between the two groups. Results: Tranexamic acid significantly reduced the quantity of blood from the end of CS to 2 h postpartum, which was 65.15±31.97 mL and 101.14±44.94 mL in the study and control groups, respectively (P =0.002). It also significantly reduced the volume of total blood from placental delivery to 2 h postpartum, which was 616.32±176.87 mL and 731.45±178.79 mL in the study and control groups (P =0.028). Total blood loss in the study group was 18.7% less than the control group. No complications or side effects were reported in the groups. Conclusions: Tranexamic acid statistically reduces the volume of blood loss from placental delivery to 2 h postpartum and its use was not associated with any side effects or complications. Therefore, tranexamic acid can be used as a safe and effective approach to reducing bleeding resulting from CS.","PeriodicalId":23249,"journal":{"name":"Trauma monthly","volume":"1 1","pages":"19-24"},"PeriodicalIF":0.5,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89879117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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Trauma monthly
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