首页 > 最新文献

Turkish Journal of Internal Medicine最新文献

英文 中文
Factors Affecting Kidney Functions in One-Year Follow-up After COVID-19 in Kidney Transplant Patients 肾移植患者COVID-19术后1年随访中影响肾功能的因素
Pub Date : 2023-01-12 DOI: 10.46310/tjim.1165344
H. Ozer, I. Baloglu, Yasin Öztürk, Fethi Yönet, H. Tonbul, N. Selcuk, Kultigin Türkmen
Background Coronavirus disease (COVID-19) is more severe, and mortality is higher in kidney transplantation (KTx) patients; it is still unclear how renal functions progress and the conditions affecting renal functions in the post-COVID-19 period. We aimed to investigate the changes in kidney functions and the factors affecting this change after COVID-19. Material and Methods Forty-one kidney transplantation patients who were hospitalised for COVID-19 were included in this retrospective study. The patient's personal information, examination, and treatment information regarding their hospitalisation and follow-ups were obtained from the hospital system. Results Patients with elevated serum creatinine in the first year post-COVID had higher baseline proteinuria and systemic immune inflammation index (SII). Proteinuria increased more in patients with a long transplantation period, hypertension, high basal creatinine, and SII. Also, proteinuria was higher in patients who developed AKI during the COVID period. In addition, baseline SII was an independent predictor of the change in serum creatinine and proteinuria. Conclusions We found that patients with signs of increased inflammation, such as high SII were more fragile regarding renal functions. Therefore, the post-COVID-19 follow-up process of KTx patients with COVID-19 should be individualised.
背景冠状病毒病(COVID-19)在肾移植(KTx)患者中更为严重,死亡率更高;新冠肺炎后肾脏功能的进展和影响肾功能的情况尚不清楚。我们旨在探讨COVID-19后肾脏功能的变化及其影响因素。材料与方法回顾性分析41例因COVID-19住院的肾移植患者。从医院系统获取患者的个人信息、检查信息、住院和随访的治疗信息。结果新冠肺炎后1年内血清肌酐升高的患者基线蛋白尿和全身免疫炎症指数(SII)较高。在移植期长、高血压、高基础肌酐和SII患者中,蛋白尿增加更多。此外,在COVID期间发生AKI的患者中蛋白尿较高。此外,基线SII是血清肌酐和蛋白尿变化的独立预测因子。结论:我们发现有炎症增加迹象的患者,如高SII,在肾功能方面更脆弱。因此,KTx患者COVID-19后随访过程应个体化。
{"title":"Factors Affecting Kidney Functions in One-Year Follow-up After COVID-19 in Kidney Transplant Patients","authors":"H. Ozer, I. Baloglu, Yasin Öztürk, Fethi Yönet, H. Tonbul, N. Selcuk, Kultigin Türkmen","doi":"10.46310/tjim.1165344","DOIUrl":"https://doi.org/10.46310/tjim.1165344","url":null,"abstract":"Background Coronavirus disease (COVID-19) is more severe, and mortality is higher in kidney transplantation (KTx) patients; it is still unclear how renal functions progress and the conditions affecting renal functions in the post-COVID-19 period. We aimed to investigate the changes in kidney functions and the factors affecting this change after COVID-19. \u0000Material and Methods Forty-one kidney transplantation patients who were hospitalised for COVID-19 were included in this retrospective study. The patient's personal information, examination, and treatment information regarding their hospitalisation and follow-ups were obtained from the hospital system. \u0000Results Patients with elevated serum creatinine in the first year post-COVID had higher baseline proteinuria and systemic immune inflammation index (SII). Proteinuria increased more in patients with a long transplantation period, hypertension, high basal creatinine, and SII. Also, proteinuria was higher in patients who developed AKI during the COVID period. In addition, baseline SII was an independent predictor of the change in serum creatinine and proteinuria. \u0000Conclusions We found that patients with signs of increased inflammation, such as high SII were more fragile regarding renal functions. Therefore, the post-COVID-19 follow-up process of KTx patients with COVID-19 should be individualised.","PeriodicalId":23372,"journal":{"name":"Turkish Journal of Internal Medicine","volume":"100 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72845205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Positive status of Hepatis B Virus seroprevalence in local people and immigrants 本地及外来人口乙型肝炎病毒血清阳性率分析
Pub Date : 2023-01-09 DOI: 10.46310/tjim.1215109
Salih Metin, C. Demir
Background In our study, we aimed to examine the seroprevalence of hepatitis B virus (HBV) infection and whether there is a sociodemographic difference between the two groups according to the hepatitis B surface antigen (HBsAg) results obtained in the blood samples given by the Turkish population and Syrian immigrants living in Bursa in their primary, secondary, and tertiary care applications. Material and Methods All patients with HBsAg serology who applied to family health centers, migrant health centers, 2nd and 3rd level hospitals in Bursa province during the 5-year period from January 2017 to the end of December 2021 were included in our study. Results During our study, HBsAg tests were taken from 955,528 people until the end of 2017-2021. The rate of Turkish citizens was 96.1% (n: 918,140), and the rate of Syrian origin was 3.9% (n: 37,388). Of all patients, 39.4% (n: 376,388) were male, and 60.6% (n: 579,140) were female. The HBsAg test was negative in 96.4% (n: 921,582) and positive in 3.6% (n: 33,946) of the patients. HBsAg positivity was found to be 3.6% in Turks and 2.4% in Syrians. HBsAg positivity was found to be 4.6% in men and 2.9% in women. The highest HBsAg positivity rate was 7.4% in the 50-59 age group. Conclusions The dissemination of the hepatitis B vaccine, which is currently in use, seems to be the most crucial weapon in the hands of humanity to prevent this infection and the diseases it will cause.
在我们的研究中,我们的目的是检查乙型肝炎病毒(HBV)感染的血清阳性率,以及根据居住在布尔萨的土耳其人口和叙利亚移民在其初级、二级和三级保健应用中提供的血液样本中获得的乙型肝炎表面抗原(HBsAg)结果,两组之间是否存在社会人口统计学差异。材料与方法纳入2017年1月至2021年12月底5年间在布尔萨省家庭卫生院、流动人口卫生院、二、三级医院就诊的所有HBsAg血清学患者。在我们的研究中,截至2017-2021年底,对955,528人进行了HBsAg检测。土耳其公民占96.1% (n: 918,140),叙利亚裔占3.9% (n: 37,388)。在所有患者中,39.4% (n: 376,388)为男性,60.6% (n: 579,140)为女性。HBsAg检测为阴性的占96.4% (n: 921,582),阳性的占3.6% (n: 33,946)。土耳其人和叙利亚人的HBsAg阳性率分别为3.6%和2.4%。HBsAg阳性男性为4.6%,女性为2.9%。50 ~ 59岁年龄组HBsAg阳性率最高,为7.4%。结论目前正在使用的乙型肝炎疫苗的传播似乎是人类手中预防这种感染及其将引起的疾病的最关键武器。
{"title":"Positive status of Hepatis B Virus seroprevalence in local people and immigrants","authors":"Salih Metin, C. Demir","doi":"10.46310/tjim.1215109","DOIUrl":"https://doi.org/10.46310/tjim.1215109","url":null,"abstract":"Background In our study, we aimed to examine the seroprevalence of hepatitis B virus (HBV) infection and whether there is a sociodemographic difference between the two groups according to the hepatitis B surface antigen (HBsAg) results obtained in the blood samples given by the Turkish population and Syrian immigrants living in Bursa in their primary, secondary, and tertiary care applications. \u0000Material and Methods All patients with HBsAg serology who applied to family health centers, migrant health centers, 2nd and 3rd level hospitals in Bursa province during the 5-year period from January 2017 to the end of December 2021 were included in our study. \u0000Results During our study, HBsAg tests were taken from 955,528 people until the end of 2017-2021. The rate of Turkish citizens was 96.1% (n: 918,140), and the rate of Syrian origin was 3.9% (n: 37,388). Of all patients, 39.4% (n: 376,388) were male, and 60.6% (n: 579,140) were female. The HBsAg test was negative in 96.4% (n: 921,582) and positive in 3.6% (n: 33,946) of the patients. HBsAg positivity was found to be 3.6% in Turks and 2.4% in Syrians. HBsAg positivity was found to be 4.6% in men and 2.9% in women. The highest HBsAg positivity rate was 7.4% in the 50-59 age group. \u0000Conclusions The dissemination of the hepatitis B vaccine, which is currently in use, seems to be the most crucial weapon in the hands of humanity to prevent this infection and the diseases it will cause.","PeriodicalId":23372,"journal":{"name":"Turkish Journal of Internal Medicine","volume":"438 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73594879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pulmonary Complications in Renal Transplant Recipients 肾移植受者的肺部并发症
Pub Date : 2022-11-23 DOI: 10.46310/tjim.1110191
Nursel Türkoğlu Selçuk, Füsun Öner Eyuboglu, Nevra Güllü Arslan, M. Haberal
Background Kidney transplantation recipients are at an increased risk of lung complications due to infectious or non-infectious reasons. We aimed to determine the lung complications after transplantation and what we could do to prevent the complications during the follow-up, retrospectively. Material and Methods The 296 patients who underwent kidney transplantation surgery in our centre between the years 1999 to 2006 were included in the study. Results 75% of the patients were male (n: 222). 77% of the patients (n: 228) had a living-related donor. The mean hospitalisation duration in the post-transplantation period was 13.3±9.07 days. During the follow-up, 37.2% of the patients (n: 110) had rejection, and pulse steroid treatments were given to the 74.5% of these patients. In our study, the lung complication development ratio was 16.2%, and 84% of these complications were due to infections. A specific aetiology was not identified in 63.5% of patients. The patients with a living-related donor had more lung complications due to infection (p
背景:由于传染性或非传染性原因,肾移植受者发生肺部并发症的风险增加。我们的目的是确定移植后的肺部并发症,以及在随访中我们可以做些什么来预防并发症。材料与方法选取1999 ~ 2006年在我中心行肾移植手术的296例患者为研究对象。结果男性占75%(222例)。77%的患者(228例)有活体供体。移植后平均住院时间为13.3±9.07天。随访期间,有37.2%的患者(110例)出现排斥反应,其中74.5%的患者接受了脉冲类固醇治疗。在我们的研究中,肺部并发症的发生率为16.2%,其中84%的并发症是由感染引起的。63.5%的患者没有确定特定的病因。有活体供体的患者有更多的肺部感染并发症(p
{"title":"Pulmonary Complications in Renal Transplant Recipients","authors":"Nursel Türkoğlu Selçuk, Füsun Öner Eyuboglu, Nevra Güllü Arslan, M. Haberal","doi":"10.46310/tjim.1110191","DOIUrl":"https://doi.org/10.46310/tjim.1110191","url":null,"abstract":"Background Kidney transplantation recipients are at an increased risk of lung complications due to infectious or non-infectious reasons. We aimed to determine the lung complications after transplantation and what we could do to prevent the complications during the follow-up, retrospectively. \u0000Material and Methods The 296 patients who underwent kidney transplantation surgery in our centre between the years 1999 to 2006 were included in the study. \u0000Results 75% of the patients were male (n: 222). 77% of the patients (n: 228) had a living-related donor. The mean hospitalisation duration in the post-transplantation period was 13.3±9.07 days. During the follow-up, 37.2% of the patients (n: 110) had rejection, and pulse steroid treatments were given to the 74.5% of these patients. In our study, the lung complication development ratio was 16.2%, and 84% of these complications were due to infections. A specific aetiology was not identified in 63.5% of patients. The patients with a living-related donor had more lung complications due to infection (p","PeriodicalId":23372,"journal":{"name":"Turkish Journal of Internal Medicine","volume":"71 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83937037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The relationship between the frequency and severity of restless legs syndrome and anaemia in patients with ankylosing spondylitis 强直性脊柱炎患者不宁腿综合征发生频率和严重程度与贫血的关系
Pub Date : 2022-11-23 DOI: 10.46310/tjim.1177257
Hasan Göğebakan, Ayşegül Akyüz
Background Background The study aims to determine the frequency of restless legs syndrome (RLS) in patients with ankylosing spondylitis (AS) and the relationship between the International Restless Legs Syndrome Study Group Rating Scale (IRLSSG-RS) score and anemia. Material and Methods It was a case-control study that included 106 patients with AS and 106 age- and sex-matched healthy controls in the rheumatology clinic of a training and research hospital. The patients were divided into two groups according to their hemoglobin levels. A hemoglobin level lower than 12 g/dL in women and less than 13 g/dL in men was the criterion for anemia. Results Although the frequency of RLS was higher in AS patients than in control groups, there was no significant difference in the IRLSSG-RS score between AS patients and control groups. 23 (57.5%) of the AS patients with anemia had RLS, and the IRLSSG-RS score was 21.3±5.7. Of the AS patients without anemia, 11 (16.7%) had RLS, and the IRLSSG-RS score was 15±6. Statistically significant differences between AS patients with and without anemia regarding RLS frequency and IRLSSG-RS score were found. The IRLSSG-RS scores of AS patients were negatively correlated with serum iron and hemoglobin level. Conclusions Patients with AS had a higher RLS frequency than the control group; AS patients with anemia had a higher RLS and IRLSSG-RS score than AS patients without anemia. Also, a negative and significant correlation was found between the IRLSS-RS score and serum iron and hemoglobin levels in AS patients.
本研究旨在确定强直性脊柱炎(AS)患者不宁腿综合征(RLS)的发生频率,以及国际不宁腿综合征研究组评定量表(IRLSSG-RS)评分与贫血的关系。材料和方法这是一项病例对照研究,包括106名AS患者和106名年龄和性别匹配的健康对照者,他们来自一家培训和研究医院的风湿病门诊。根据血红蛋白水平将患者分为两组。血红蛋白水平低于12g /dL的女性和低于13g /dL的男性是贫血的标准。结果AS患者的RLS发生率高于对照组,但IRLSSG-RS评分与对照组比较差异无统计学意义。AS合并贫血患者中有23例(57.5%)发生RLS, IRLSSG-RS评分为21.3±5.7分。无贫血的AS患者中有11例(16.7%)发生RLS, IRLSSG-RS评分为15±6分。伴有和不伴有贫血的AS患者在RLS频率和IRLSSG-RS评分方面存在统计学差异。AS患者IRLSSG-RS评分与血清铁、血红蛋白水平呈负相关。结论AS患者的RLS发生率高于对照组;贫血AS患者的RLS和IRLSSG-RS评分高于无贫血AS患者。此外,AS患者IRLSS-RS评分与血清铁和血红蛋白水平呈显著负相关。
{"title":"The relationship between the frequency and severity of restless legs syndrome and anaemia in patients with ankylosing spondylitis","authors":"Hasan Göğebakan, Ayşegül Akyüz","doi":"10.46310/tjim.1177257","DOIUrl":"https://doi.org/10.46310/tjim.1177257","url":null,"abstract":"Background Background The study aims to determine the frequency of restless legs syndrome (RLS) in patients with ankylosing spondylitis (AS) and the relationship between the International Restless Legs Syndrome Study Group Rating Scale (IRLSSG-RS) score and anemia. \u0000Material and Methods It was a case-control study that included 106 patients with AS and 106 age- and sex-matched healthy controls in the rheumatology clinic of a training and research hospital. The patients were divided into two groups according to their hemoglobin levels. A hemoglobin level lower than 12 g/dL in women and less than 13 g/dL in men was the criterion for anemia. \u0000Results Although the frequency of RLS was higher in AS patients than in control groups, there was no significant difference in the IRLSSG-RS score between AS patients and control groups. 23 (57.5%) of the AS patients with anemia had RLS, and the IRLSSG-RS score was 21.3±5.7. Of the AS patients without anemia, 11 (16.7%) had RLS, and the IRLSSG-RS score was 15±6. Statistically significant differences between AS patients with and without anemia regarding RLS frequency and IRLSSG-RS score were found. The IRLSSG-RS scores of AS patients were negatively correlated with serum iron and hemoglobin level. \u0000Conclusions Patients with AS had a higher RLS frequency than the control group; AS patients with anemia had a higher RLS and IRLSSG-RS score than AS patients without anemia. Also, a negative and significant correlation was found between the IRLSS-RS score and serum iron and hemoglobin levels in AS patients.","PeriodicalId":23372,"journal":{"name":"Turkish Journal of Internal Medicine","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89926770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biological Agent Use in Behçet's Patients Who Are Resistant to Conventional Treatments: A Multidisciplinary Retrospective Study 生物制剂用于对常规治疗有耐药性的behet患者:一项多学科回顾性研究
Pub Date : 2022-11-18 DOI: 10.46310/tjim.1144532
B. Yağız, B. N. Coşkun, Zeliha Kubra Cakan, Gamze Uçan Gündüz, Özgür Yalçınbayır, Serkan Yazici, H. Saricaoğlu, H. E. Dalkılıç, Y. Pehlivan
Background Comparing treatment modalities is difficult in Behcet's syndrome, even if tumour necrosis factor-alpha (TNF-α) inhibitors are a treatment option for all involvements resistant to conventional therapy. This study evaluated how different departments dealt with treatment, particularly with TNF-α inhibitors. Material and Methods The study comprised 111 patients from our Behcet's syndrome cohort who were treated with TNF-α inhibitors between 2010 and 2019. Data on patients were retrieved retrospectively from the rheumatology, ophthalmology, and dermatology clinics' patient records. Results Patients followed up in rheumatology (n: 40) were classified as Group 1, and patients followed up in ophthalmology (n: 49) and dermatology (n: 5) as Group 2. In Group 1, genital ulcers, erythema nodosum (p=0.009, p=0.003, respectively), lower extremity deep vein thrombosis, arterial aneurysm and neurological involvement were more common (p=0.005, p=0.008, p=0.001, respectively). In Group 2, the use of cyclosporine and interferon-α before the anti-TNF agent was higher (p
背景:即使肿瘤坏死因子-α (TNF-α)抑制剂是一种对常规治疗有抵抗性的所有受累的治疗选择,比较Behcet综合征的治疗方式也是困难的。本研究评估了不同科室如何处理治疗,特别是TNF-α抑制剂。材料和方法该研究纳入了2010年至2019年期间接受TNF-α抑制剂治疗的Behcet综合征队列中的111例患者。回顾性地检索风湿病、眼科和皮肤科诊所的患者记录。结果风湿病患者(40例)为1组,眼科患者(49例)和皮肤科患者(5例)为2组。1组中生殖器溃疡、结节性红斑(p=0.009, p=0.003)、下肢深静脉血栓形成、动脉动脉瘤、神经系统受累更为常见(p=0.005, p=0.008, p=0.001)。在第2组中,在使用抗肿瘤坏死因子药物之前,环孢素和干扰素-α的使用较高(p
{"title":"Biological Agent Use in Behçet's Patients Who Are Resistant to Conventional Treatments: A Multidisciplinary Retrospective Study","authors":"B. Yağız, B. N. Coşkun, Zeliha Kubra Cakan, Gamze Uçan Gündüz, Özgür Yalçınbayır, Serkan Yazici, H. Saricaoğlu, H. E. Dalkılıç, Y. Pehlivan","doi":"10.46310/tjim.1144532","DOIUrl":"https://doi.org/10.46310/tjim.1144532","url":null,"abstract":"Background Comparing treatment modalities is difficult in Behcet's syndrome, even if tumour necrosis factor-alpha (TNF-α) inhibitors are a treatment option for all involvements resistant to conventional therapy. This study evaluated how different departments dealt with treatment, particularly with TNF-α inhibitors. \u0000Material and Methods The study comprised 111 patients from our Behcet's syndrome cohort who were treated with TNF-α inhibitors between 2010 and 2019. Data on patients were retrieved retrospectively from the rheumatology, ophthalmology, and dermatology clinics' patient records. \u0000Results Patients followed up in rheumatology (n: 40) were classified as Group 1, and patients followed up in ophthalmology (n: 49) and dermatology (n: 5) as Group 2. In Group 1, genital ulcers, erythema nodosum (p=0.009, p=0.003, respectively), lower extremity deep vein thrombosis, arterial aneurysm and neurological involvement were more common (p=0.005, p=0.008, p=0.001, respectively). In Group 2, the use of cyclosporine and interferon-α before the anti-TNF agent was higher (p","PeriodicalId":23372,"journal":{"name":"Turkish Journal of Internal Medicine","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83460067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The use of ultrasonography to guide diagnosis and treatment in resuscitation in a case of arrest due to pulmonary embolism 超声在肺栓塞致骤停复苏中的诊断和治疗指导
Pub Date : 2022-11-18 DOI: 10.46310/tjim.1069084
Agit Akgül
Pulmonary embolism is one of the reversible causes of death. Simultaneous diagnostic procedures are beneficial for successfully resuscitating patients brought to the emergency department as an arrest after pulmonary embolism. Ultrasonography is one of the few diagnostic procedures to be performed on an unstable patient during resuscitation and is a direct guide for treatment. We followed the passage of the thrombus from the inferior vena cava to the right atrium in the ultrasonography performed simultaneously with the resuscitation of the 76-year-old male patient who was brought to the hospital with arrest, and we started thrombolytic therapy simultaneously with resuscitation. Thrombus enlargement was observed in the right atrium. The patient who did not respond to resuscitation died. Although the causes of reversible arrest are known, there may be uncertainties in diagnostic procedures and treatment during resuscitation. Classical resuscitation practice may be insufficient to solve reversible problems such as pulmonary embolism. Although there are reservations about the inclusion of point-of-care ultrasound in resuscitation, it can play a life-saving role.
肺栓塞是可逆的死亡原因之一。同时诊断程序是有益的,成功复苏的病人被带到急诊科作为肺栓塞后骤停。超声检查是在复苏过程中对不稳定患者进行的少数诊断程序之一,是治疗的直接指导。76岁男性患者因骤停入院,我们在抢救的同时进行超声检查,跟踪血栓从下腔静脉流向右心房,并在抢救的同时开始溶栓治疗。右心房血栓增大。对复苏无反应的病人死亡。虽然可逆骤停的原因是已知的,但在复苏期间的诊断程序和治疗可能存在不确定性。经典的复苏实践可能不足以解决可逆性问题,如肺栓塞。尽管对在复苏中使用即时超声有保留意见,但它确实可以起到挽救生命的作用。
{"title":"The use of ultrasonography to guide diagnosis and treatment in resuscitation in a case of arrest due to pulmonary embolism","authors":"Agit Akgül","doi":"10.46310/tjim.1069084","DOIUrl":"https://doi.org/10.46310/tjim.1069084","url":null,"abstract":"Pulmonary embolism is one of the reversible causes of death. Simultaneous diagnostic procedures are beneficial for successfully resuscitating patients brought to the emergency department as an arrest after pulmonary embolism. Ultrasonography is one of the few diagnostic procedures to be performed on an unstable patient during resuscitation and is a direct guide for treatment. We followed the passage of the thrombus from the inferior vena cava to the right atrium in the ultrasonography performed simultaneously with the resuscitation of the 76-year-old male patient who was brought to the hospital with arrest, and we started thrombolytic therapy simultaneously with resuscitation. Thrombus enlargement was observed in the right atrium. The patient who did not respond to resuscitation died. Although the causes of reversible arrest are known, there may be uncertainties in diagnostic procedures and treatment during resuscitation. Classical resuscitation practice may be insufficient to solve reversible problems such as pulmonary embolism. Although there are reservations about the inclusion of point-of-care ultrasound in resuscitation, it can play a life-saving role.","PeriodicalId":23372,"journal":{"name":"Turkish Journal of Internal Medicine","volume":"100 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90661638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Paraoxonase Activity an Independent Contributor in SARS-CoV-2 Infection 对氧磷酶活性是SARS-CoV-2感染的独立因素
Pub Date : 2022-10-25 DOI: 10.46310/tjim.1092894
M. Mogarekar, Pushpa Rajan, Mahendra G. Dhabe, Rahul Zine
Background The aim of the present study was the estimation of serum paraoxonase (PON1) activity in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Material and Methods In this cross-sectional study we estimated serum paraoxonase activity in 73 patients with SARS-CoV-2 infection and 73 healthy controls. Results The results showed that PON1 activity was significantly decreased in patients with SARS-CoV-2 (1.30±0.55 kU/L) than in healthy controls (1.913±0.48 kU/L, p
本研究的目的是评估严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)患者血清对氧磷酶(PON1)的活性。在这项横断面研究中,我们估计了73例SARS-CoV-2感染患者和73名健康对照者的血清对氧磷酶活性。结果SARS-CoV-2患者PON1活性(1.30±0.55 kU/L)明显低于健康对照组(1.913±0.48 kU/L)
{"title":"Paraoxonase Activity an Independent Contributor in SARS-CoV-2 Infection","authors":"M. Mogarekar, Pushpa Rajan, Mahendra G. Dhabe, Rahul Zine","doi":"10.46310/tjim.1092894","DOIUrl":"https://doi.org/10.46310/tjim.1092894","url":null,"abstract":"Background The aim of the present study was the estimation of serum paraoxonase (PON1) activity in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). \u0000Material and Methods In this cross-sectional study we estimated serum paraoxonase activity in 73 patients with SARS-CoV-2 infection and 73 healthy controls. \u0000Results The results showed that PON1 activity was significantly decreased in patients with SARS-CoV-2 (1.30±0.55 kU/L) than in healthy controls (1.913±0.48 kU/L, p","PeriodicalId":23372,"journal":{"name":"Turkish Journal of Internal Medicine","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88478802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Case report: Primary hyperparathyroidism due to mediastinal parathyroid adenoma 病例报告:纵隔甲状旁腺瘤致原发性甲状旁腺功能亢进
Pub Date : 2022-10-17 DOI: 10.46310/tjim.1172821
Radmila Milosheska, I. Mickovski, Biljana Crcareva, Daniela BUKLİOSKA ILİJEVSKA, Smiljana Bundovska Kocev
Primary hyperparathyroidism is defined by elevated parathyroid hormone and calcium levels, most usually caused by a parathyroid adenoma. Parathyroid adenomas are most commonly detected in the neck or an ectopic site, seldom in the mediastinum. The parathyroid adenoma can occur in ectopic locations such as the mediastinum, thymus, or retro oesophagal area in 6-16% of cases. We presented the example of a 73-year-old woman who was found to have hypercalcemia during a regular test. The patient’s serum calcium (3.11 mmol/L), alkaline phosphatase (162 U/L), parathyroid hormone (PTH: 379 pg/mL) and creatinine (111.6 umol/L) levels were higher than the reference values. A chest computerized tomography scan revealed an anterior mediastinal mass, and nuclear scintigraphy revealed functioning parathyroid tissue in the mediastinum. The mediastinal parathyroid adenoma was effectively removed surgically, and the PTH level began to fall. Any hypercalcemia and high PTH levels in the absence of a parathyroid adenoma in the neck should prompt clinicians to look for ectopic sites using a mix of imaging modalities.
原发性甲状旁腺功能亢进的定义是甲状旁腺激素和钙水平升高,通常由甲状旁腺瘤引起。甲状旁腺瘤最常见于颈部或异位部位,很少见于纵隔。甲状旁腺瘤可发生在异位部位,如纵隔、胸腺或后食道区,占6-16%。我们提出了一个73岁的妇女谁被发现有高钙血症在常规测试的例子。患者血清钙(3.11 mmol/L)、碱性磷酸酶(162 U/L)、甲状旁腺激素(PTH: 379 pg/mL)、肌酐(111.6 umol/L)水平均高于参考值。胸部电脑断层扫描显示前纵隔肿块,核显像显示在纵隔功能甲状旁腺组织。纵隔甲状旁腺瘤手术切除有效,甲状旁腺素水平开始下降。在颈部没有甲状旁腺瘤的情况下,任何高钙血症和高甲状旁腺激素水平都应提示临床医生使用混合成像方式寻找异位部位。
{"title":"Case report: Primary hyperparathyroidism due to mediastinal parathyroid adenoma","authors":"Radmila Milosheska, I. Mickovski, Biljana Crcareva, Daniela BUKLİOSKA ILİJEVSKA, Smiljana Bundovska Kocev","doi":"10.46310/tjim.1172821","DOIUrl":"https://doi.org/10.46310/tjim.1172821","url":null,"abstract":"Primary hyperparathyroidism is defined by elevated parathyroid hormone and calcium levels, most usually caused by a parathyroid adenoma. Parathyroid adenomas are most commonly detected in the neck or an ectopic site, seldom in the mediastinum. The parathyroid adenoma can occur in ectopic locations such as the mediastinum, thymus, or retro oesophagal area in 6-16% of cases. We presented the example of a 73-year-old woman who was found to have hypercalcemia during a regular test. The patient’s serum calcium (3.11 mmol/L), alkaline phosphatase (162 U/L), parathyroid hormone (PTH: 379 pg/mL) and creatinine (111.6 umol/L) levels were higher than the reference values. A chest computerized tomography scan revealed an anterior mediastinal mass, and nuclear scintigraphy revealed functioning parathyroid tissue in the mediastinum. The mediastinal parathyroid adenoma was effectively removed surgically, and the PTH level began to fall. Any hypercalcemia and high PTH levels in the absence of a parathyroid adenoma in the neck should prompt clinicians to look for ectopic sites using a mix of imaging modalities.","PeriodicalId":23372,"journal":{"name":"Turkish Journal of Internal Medicine","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87123056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nursing Management Of The Patient Developing Quadriplegia Due To Neurological Involvement After Covid-19: A Case Report 新冠肺炎后神经系统受累致四肢瘫痪患者的护理管理1例
Pub Date : 2022-10-08 DOI: 10.46310/tjim.1112662
F. Akduran, Bahar Emi̇roğlu
COVID-19 first emerged in China, spread quickly, and was declared a pandemic by the World Health Organization. Neurological complications have led to important symptoms in patients diagnosed with COVID-19. These symptoms have substantially affected patients' quality of life, caused them to depend on others, and prolonged their recovery processes with anxiety and hopelessness. In this case report, the care process applied to an individual who developed quadriplegia due to neurological involvement after COVID-19, according to the "Nursing Model Based on Activities of Living", is shared. With effective evidence-based nursing care, the patient's quality of life was improved, existing problems were alleviated, and the patient was protected against complications.
新冠肺炎最早出现在中国,传播迅速,被世界卫生组织宣布为大流行。神经系统并发症导致被诊断为COVID-19的患者出现重要症状。这些症状严重影响了患者的生活质量,使他们依赖他人,并延长了他们的康复过程,使他们感到焦虑和绝望。在本病例报告中,根据“基于生活活动的护理模式”,分享了COVID-19后因神经系统受累而出现四肢瘫痪的个体的护理过程。通过有效的循证护理,提高了患者的生活质量,缓解了存在的问题,保护了患者免受并发症的发生。
{"title":"Nursing Management Of The Patient Developing Quadriplegia Due To Neurological Involvement After Covid-19: A Case Report","authors":"F. Akduran, Bahar Emi̇roğlu","doi":"10.46310/tjim.1112662","DOIUrl":"https://doi.org/10.46310/tjim.1112662","url":null,"abstract":"COVID-19 first emerged in China, spread quickly, and was declared a pandemic by the World Health Organization. Neurological complications have led to important symptoms in patients diagnosed with COVID-19. These symptoms have substantially affected patients' quality of life, caused them to depend on others, and prolonged their recovery processes with anxiety and hopelessness. In this case report, the care process applied to an individual who developed quadriplegia due to neurological involvement after COVID-19, according to the \"Nursing Model Based on Activities of Living\", is shared. With effective evidence-based nursing care, the patient's quality of life was improved, existing problems were alleviated, and the patient was protected against complications.","PeriodicalId":23372,"journal":{"name":"Turkish Journal of Internal Medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82164078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
General Characteristics of Palliative Care Patients Admitted to the Emergency Department 急诊科姑息治疗患者的一般特征
Pub Date : 2022-10-07 DOI: 10.46310/tjim.1146947
A. Yilmaz, H. I. Çikriklar, V. Durak, B. Kurtoğlu, S. Atmaca, S. Eraybar, Feyzullah Faruk Seçki̇n, H. Çelebi̇, E. Armağan
Background This study aimed to analyze patients who apply to emergency services and need palliative care regarding appropriate patient care and effective use of health institutions. Materials and Methods The study was conducted prospectively on patients who applied to the emergency services of Bursa Uludag University Health Application and Research Center, Health Sciences University Bursa Yüksek Ihtisas Training and Research Hospital and Bursa City Hospital between 15.08.2021 and 15.02.2022 and needed palliative care. Results A total of 261 patients, 143 male (54.8%) and 118 female (45.2%), were included in the study. It was determined that 50 (19.1%) of these patients had previously received palliative care services. It was determined that the patients included in the study applied to the emergency services 7.52±6.77 times in the last year. The three most common diseases diagnosed in patients admitted to the emergency department were pneumonia (24.5%), urinary system infection (7.7%), and cerebrovascular disease (5.4%). Of the patients, 39.84% were referred/hospitalized, 25.28% were referred/hospitalized to intensive care units, 2.68% refused treatment, 2.68% died, and 29.5% have been discharged. Conclusion As a result, it is understood that most of the patients in need of palliative care do not receive this service, and patients who can be treated in palliative care units are treated in clinics and intensive care units.
本研究旨在分析申请急诊服务和需要姑息治疗的患者在适当的患者护理和有效利用卫生机构方面的情况。材料与方法前瞻性研究于2021年8月15日至2022年2月15日期间申请Bursa Uludag大学健康应用与研究中心、健康科学大学Bursa y ksek Ihtisas培训与研究医院和Bursa City医院急诊服务并需要姑息治疗的患者。结果共纳入261例患者,其中男性143例(54.8%),女性118例(45.2%)。这些患者中有50人(19.1%)曾接受过姑息治疗服务。纳入研究的患者在过去一年中使用急救服务的次数为7.52±6.77次。急诊科住院患者诊断出的三种最常见疾病分别是肺炎(24.5%)、泌尿系统感染(7.7%)和脑血管疾病(5.4%)。39.84%的患者转诊/住院,25.28%的患者转诊/住院至重症监护病房,2.68%的患者拒绝治疗,2.68%的患者死亡,29.5%的患者已出院。结论据了解,大部分需要姑息治疗的患者并没有得到这项服务,可以在姑息治疗单位治疗的患者都在诊所和重症监护病房接受治疗。
{"title":"General Characteristics of Palliative Care Patients Admitted to the Emergency Department","authors":"A. Yilmaz, H. I. Çikriklar, V. Durak, B. Kurtoğlu, S. Atmaca, S. Eraybar, Feyzullah Faruk Seçki̇n, H. Çelebi̇, E. Armağan","doi":"10.46310/tjim.1146947","DOIUrl":"https://doi.org/10.46310/tjim.1146947","url":null,"abstract":"Background This study aimed to analyze patients who apply to emergency services and need palliative care regarding appropriate patient care and effective use of health institutions. \u0000Materials and Methods The study was conducted prospectively on patients who applied to the emergency services of Bursa Uludag University Health Application and Research Center, Health Sciences University Bursa Yüksek Ihtisas Training and Research Hospital and Bursa City Hospital between 15.08.2021 and 15.02.2022 and needed palliative care. \u0000Results A total of 261 patients, 143 male (54.8%) and 118 female (45.2%), were included in the study. It was determined that 50 (19.1%) of these patients had previously received palliative care services. It was determined that the patients included in the study applied to the emergency services 7.52±6.77 times in the last year. The three most common diseases diagnosed in patients admitted to the emergency department were pneumonia (24.5%), urinary system infection (7.7%), and cerebrovascular disease (5.4%). Of the patients, 39.84% were referred/hospitalized, 25.28% were referred/hospitalized to intensive care units, 2.68% refused treatment, 2.68% died, and 29.5% have been discharged. \u0000Conclusion As a result, it is understood that most of the patients in need of palliative care do not receive this service, and patients who can be treated in palliative care units are treated in clinics and intensive care units.","PeriodicalId":23372,"journal":{"name":"Turkish Journal of Internal Medicine","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89809802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Turkish Journal of Internal Medicine
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1