Cutaneous drug reactions usually occur with mild and self-limiting lesions, but severe forms can be life-threatening. Non-steroidal anti-inflammatory drugs, antibiotics
{"title":"Drug Eruptions with Cases: Fixed Drug Eruption and DRESS Syndrome","authors":"Şeyma Handan Akyön, Yeser Genc","doi":"10.46310/tjim.1066277","DOIUrl":"https://doi.org/10.46310/tjim.1066277","url":null,"abstract":"Cutaneous drug reactions usually occur with mild and self-limiting lesions, but severe forms can be life-threatening. Non-steroidal anti-inflammatory drugs, antibiotics","PeriodicalId":23372,"journal":{"name":"Turkish Journal of Internal Medicine","volume":"59 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85566644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nasal Cavity Neuroendocrine Carcinoma and Synchronous Breast Cancer: A Case Report","authors":"Asuman Şebnem Hacimustafaoğlu, A. Deligönül","doi":"10.46310/tjim.1073665","DOIUrl":"https://doi.org/10.46310/tjim.1073665","url":null,"abstract":"","PeriodicalId":23372,"journal":{"name":"Turkish Journal of Internal Medicine","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86201605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retrospective evaluation of microalbuminuria and GFR levels of diabetic patients taking DPP-4 Inhibitor, GLP-1 Analog, or SGLT-2 Inhibitor","authors":"Bahriye Gültaş, Özen Özgül, S. Cander","doi":"10.46310/tjim.1072857","DOIUrl":"https://doi.org/10.46310/tjim.1072857","url":null,"abstract":"","PeriodicalId":23372,"journal":{"name":"Turkish Journal of Internal Medicine","volume":"72 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88306520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background To examine the relationship between an institutionally prepared standardized patient evaluation form and the Edmonton Frail Scale (EFS) in patients receiving home health care. Material and Methods Our prospective, observational study included 200 patients over the age of 18 who requested home health care, regardless of gender. The EFS and institutional data collection forms were applied consecutively on the same day to all patients included in the study. Results Among the 200 individuals recruited for the study, 59% were female and 41% were male; the overall average age was 80 years. According to the EFS results, 4.5% of the patients were classified as non-frail, 6% were vulnerable, and 89.5% had varying degrees of frailty (mild, moderate and severe). There was a significant positive correlation between EFS score and age (p
{"title":"Determining the frailty status in patients who apply for home health care","authors":"Zeynep ERDEM SANCAK, C. Haki, Hakan Demirci","doi":"10.46310/tjim.988602","DOIUrl":"https://doi.org/10.46310/tjim.988602","url":null,"abstract":"Background To examine the relationship between an institutionally prepared standardized patient evaluation form and the Edmonton Frail Scale (EFS) in patients receiving home health care. \u0000Material and Methods Our prospective, observational study included 200 patients over the age of 18 who requested home health care, regardless of gender. The EFS and institutional data collection forms were applied consecutively on the same day to all patients included in the study. \u0000Results Among the 200 individuals recruited for the study, 59% were female and 41% were male; the overall average age was 80 years. According to the EFS results, 4.5% of the patients were classified as non-frail, 6% were vulnerable, and 89.5% had varying degrees of frailty (mild, moderate and severe). There was a significant positive correlation between EFS score and age (p","PeriodicalId":23372,"journal":{"name":"Turkish Journal of Internal Medicine","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75426282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background We aimed to determine the time elapsed for switching from oral antidiabetic therapy to insulin therapy in patients with type 2 diabetes mellitus and the factors that affect this period. Material and Methods Three hundred fifteen patients with type 2 diabetes mellitus who were followed up in the diabetes outpatient clinic were included in the study. The gender, education level, age of onset of diabetes, presence of hypertension, smoking and body mass index of the patients were examined, and the effects of these variables on time elapsed for switching to insulin therapy were analyzed in three phases. Results Three hundred fifteen patients (117 males, 198 females) were enrolled in the study. The mean time elapsed for switching from oral antidiabetic therapy to insulin therapy was 9.93±6.67 years. The effects of education level, age at the onset of diabetes, presence of hypertension, and body mass index on time elapsed for switching to insulin therapy were found to be statistically significant (p0.05). The time elapsed for switching to insulin therapy shortened as the education level, the age at the onset of diabetes, and body mass index level increased. It was found that hypertension in patients with type 2 diabetes mellitus prolongs the time elapsed for switching to insulin therapy. Conclusion The body mass index level, presence of hypertension, education level and age at the onset of diabetes were the significant factors affecting the time elapsed for switching to insulin therapy.
{"title":"Time Elapsed For Switching From Oral Antidiabetic Therapy to Insulin Therapy in Type 2 Diabetic Patients and Evaluation of The Factors Affecting This Period","authors":"Kadem Arslan, Ahmet Boyoglu, M. Temizel","doi":"10.46310/tjim.1038077","DOIUrl":"https://doi.org/10.46310/tjim.1038077","url":null,"abstract":"Background We aimed to determine the time elapsed for switching from oral antidiabetic therapy to insulin therapy in patients with type 2 diabetes mellitus and the factors that affect this period. \u0000Material and Methods Three hundred fifteen patients with type 2 diabetes mellitus who were followed up in the diabetes outpatient clinic were included in the study. The gender, education level, age of onset of diabetes, presence of hypertension, smoking and body mass index of the patients were examined, and the effects of these variables on time elapsed for switching to insulin therapy were analyzed in three phases. \u0000Results Three hundred fifteen patients (117 males, 198 females) were enrolled in the study. The mean time elapsed for switching from oral antidiabetic therapy to insulin therapy was 9.93±6.67 years. The effects of education level, age at the onset of diabetes, presence of hypertension, and body mass index on time elapsed for switching to insulin therapy were found to be statistically significant (p0.05). The time elapsed for switching to insulin therapy shortened as the education level, the age at the onset of diabetes, and body mass index level increased. It was found that hypertension in patients with type 2 diabetes mellitus prolongs the time elapsed for switching to insulin therapy. \u0000Conclusion The body mass index level, presence of hypertension, education level and age at the onset of diabetes were the significant factors affecting the time elapsed for switching to insulin therapy.","PeriodicalId":23372,"journal":{"name":"Turkish Journal of Internal Medicine","volume":"69 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90735703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cancer of unknown primary is defined as cancer with an unknown primary origin. Occult breast cancer (OBC) is a rare diagnosis in which physical examination, imaging methods, and even surgical procedures are insufficient to put on a primary tumoral site in the breasts. This definition leads to only 0.3-1% of all breast cancer cases. The diagnosis of OBC is usually obtained with an axillary lymph node biopsy. A 52-year-old female presented with right arm weakness and a neck lump. On the physical examination, multiple masses were palpated at the right axillary, right supraclavicular, and anterior cervical areas. Mammography, breast ultrasonography, breast magnetic resonance imaging, and 18-fluorodeoxyglucose positron emission tomography (18-FDG PET) scan could not show a suspicious tumoral area as the primary origin. 18-FDG PET scan put on the massive tumoral burden at multiple bones and lymph nodes, but there were no lesions to suspect as the tumoral origin. Finally, the supraclavicular lymph node biopsy result has revealed the diagnosis; hormone receptor-positive and C-erbB2 positive occult breast cancer. Cervical lymph node metastasis is also a scarce condition for breast cancer. The lymphatic drainage pathway is not clear in explaining the breast cancer involvement of the cervical.
{"title":"Multiple Lymph Node and Bone Metastases From An Occult Breast Cancer: A Case Report","authors":"Hasan Sözel, H. Güzel","doi":"10.46310/tjim.991565","DOIUrl":"https://doi.org/10.46310/tjim.991565","url":null,"abstract":"Cancer of unknown primary is defined as cancer with an unknown primary origin. Occult breast cancer (OBC) is a rare diagnosis in which physical examination, imaging methods, and even surgical procedures are insufficient to put on a primary tumoral site in the breasts. This definition leads to only 0.3-1% of all breast cancer cases. The diagnosis of OBC is usually obtained with an axillary lymph node biopsy. A 52-year-old female presented with right arm weakness and a neck lump. On the physical examination, multiple masses were palpated at the right axillary, right supraclavicular, and anterior cervical areas. Mammography, breast ultrasonography, breast magnetic resonance imaging, and 18-fluorodeoxyglucose positron emission tomography (18-FDG PET) scan could not show a suspicious tumoral area as the primary origin. 18-FDG PET scan put on the massive tumoral burden at multiple bones and lymph nodes, but there were no lesions to suspect as the tumoral origin. Finally, the supraclavicular lymph node biopsy result has revealed the diagnosis; hormone receptor-positive and C-erbB2 positive occult breast cancer. Cervical lymph node metastasis is also a scarce condition for breast cancer. The lymphatic drainage pathway is not clear in explaining the breast cancer involvement of the cervical.","PeriodicalId":23372,"journal":{"name":"Turkish Journal of Internal Medicine","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90791098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background Polycystic ovary syndrome (PCOS) is associated with many long term health problems such as increased risk of obesity, type 2 diabetes, metabolic syndrome and cardiovascular risk factors. Several reports indicated that PCOS patients have lower vitamin D status compared to healthy subjects. In our study we aimed to investigate whether vitamin D deficiency has effect on the pathogenesis of insulin resistance in PCOS. Material and Methods Fourty eight patients with PCOS and 24 healthy controls were included in the study. Following the physical examination and anthropometric measurements of the patients and healthy subjects, glycemic control data, lipid values, parathormone, vitamin D status and hormonal parameters were studied. Results In our study, vitamin D levels were significantly lower in PCOS patients (19.7±26.9 ng/mL) compared with controls (31.9±35 ng/mL, p<0.01). Vitamin D levels were found to be lower in the obese PCOS group compared to those with non-obese, but not significant. Statistically significant inverse correlation was found between vitamin D levels and body mass index (BMI). It was also found between vitamin D and low density cholesterol
{"title":"Evaluation of insulin resistance and vitamin D levels in patients with polycystic ovary syndrome","authors":"S. Cander, P. Şişman, Özen Öz Gül","doi":"10.46310/tjim.1027019","DOIUrl":"https://doi.org/10.46310/tjim.1027019","url":null,"abstract":"Background Polycystic ovary syndrome (PCOS) is associated with many long term health problems such as increased risk of obesity, type 2 diabetes, metabolic syndrome and cardiovascular risk factors. Several reports indicated that PCOS patients have lower vitamin D status compared to healthy subjects. In our study we aimed to investigate whether vitamin D deficiency has effect on the pathogenesis of insulin resistance in PCOS. Material and Methods Fourty eight patients with PCOS and 24 healthy controls were included in the study. Following the physical examination and anthropometric measurements of the patients and healthy subjects, glycemic control data, lipid values, parathormone, vitamin D status and hormonal parameters were studied. Results In our study, vitamin D levels were significantly lower in PCOS patients (19.7±26.9 ng/mL) compared with controls (31.9±35 ng/mL, p<0.01). Vitamin D levels were found to be lower in the obese PCOS group compared to those with non-obese, but not significant. Statistically significant inverse correlation was found between vitamin D levels and body mass index (BMI). It was also found between vitamin D and low density cholesterol","PeriodicalId":23372,"journal":{"name":"Turkish Journal of Internal Medicine","volume":"77 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90513312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Afruz Babayeva, Meriç Coşkun, M. Yalçın, S. Ünlü, H. S. Özger, Leyla Batmaz, A. Eroğlu Altinova, M. Akturk, F. Baloş Törüner, I. Yetkin
Coronavirus disease-2019 (COVID-19) has become a serious health problem in Turkey and the world. The diagnosis stage of many chronic diseases, the treatment process and the status of being affected by COVID-19 have become the focus of attention in the medical community during the pandemic, which has been continuing for nine months. We will discuss the course of COVID-19 infection over a 32-year-old and 76-year-old female patient with Cushing syndrome who applied to our clinic as a tertiary referral centre.
{"title":"Challenges in the Management of the Patients with COVID-19 Infected Cushing’s Syndrome: Two Cases And Literature Review","authors":"Afruz Babayeva, Meriç Coşkun, M. Yalçın, S. Ünlü, H. S. Özger, Leyla Batmaz, A. Eroğlu Altinova, M. Akturk, F. Baloş Törüner, I. Yetkin","doi":"10.46310/tjim.975133","DOIUrl":"https://doi.org/10.46310/tjim.975133","url":null,"abstract":"Coronavirus disease-2019 (COVID-19) has become a serious health problem in Turkey and the world. The diagnosis stage of many chronic diseases, the treatment process and the status of being affected by COVID-19 have become the focus of attention in the medical community during the pandemic, which has been continuing for nine months. We will discuss the course of COVID-19 infection over a 32-year-old and 76-year-old female patient with Cushing syndrome who applied to our clinic as a tertiary referral centre.","PeriodicalId":23372,"journal":{"name":"Turkish Journal of Internal Medicine","volume":"204 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80342129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Ekin, B. Ebik, F. Bacaksız, Ihsan Solmaz, Eşref Araç, F. Bingöl
{"title":"Evaluation of gastric polyps: a single-center study conducted in Turkey's Southeast Anatolia Region","authors":"N. Ekin, B. Ebik, F. Bacaksız, Ihsan Solmaz, Eşref Araç, F. Bingöl","doi":"10.46310/tjim.1015096","DOIUrl":"https://doi.org/10.46310/tjim.1015096","url":null,"abstract":"","PeriodicalId":23372,"journal":{"name":"Turkish Journal of Internal Medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83599867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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