Turkish Journal of Surgery最新文献

Intussusception is a rare occurrence in adults and only 5% being adults. Ileocolic intussusception is the most common type in adults whereas duodenal intussusception (DI) is the rarest subtype due to natural retroperitoneal fixation of the duodenum. There are only a few case-reports available in the literature. Here, we aimed to present our experience of five cases with DI in adults, there operative challenges and strategies to deal with the same. Age of presentation ranged from 18-45 years, and four out of five were females. Most common presentation was partial of recurrent gastric outlet obstruction (GOO) along with weight loss. They were all diagnosed on contract-enhanced-CT scan of abdomen, and all had a lead point in form of a benign polypoidal mass arising from duodenum. Two patients were managed with local excision of polyp and retroperitoneal fixation of redundant duodenum, whereas pancreaticoduodenectomy and segmental duodenal resection was required for the other two patients. One patient was lost to follow-up without definitive treatment as was minimally symptomatic. All four operated patients had uneventful recovery post-operatively and are doing well in follow-up. DI is an infrequent occurrence and a rare etiology of GOO in adults. Most of them having benign lead point, require surgical excision of lead point with fixation of duodenum to retroperitoneum. Anatomical proximity of important structures like CBD and pancreatic duct especially at perivaterian location makes surgical resection challenging. With thorough anatomical knowledge and appropriate management, this condition can be managed well.

Juvenile papillomatosis (JP) is a very rare benign proliferative breast disease, especially in young women under 30 years of age. Its etiology is not clear yet. Although some patients have breast cancer in their family history, up to 10% breast cancer can develop in the follow-up of JP patients. In this pathology, which is diagnosed with biopsy, history, clinical and radiological findings help in diagnosis. In this case report, a 37-year-old patient diagnosed with JP will be discussed in the light of the literature.

Objectives: This study aimed to determine various article characteristics influencing the citations and altmetric scores using papers published in a year in four high-ranking surgery journals.

Material and methods: We included all papers (n= 819 articles) published between January 2015 to December 2015 in the Annals of Surgery, British Journal of Surgery, JAMA Surgery and Journal of American College of Surgeons. Article characteristics were manually extracted. We determined citation count using the Web of Science database and used univariate analysis and negative binomial regression to determine which article characteristics affect citations and altmetric scores.

Results: Mean number of citations and altmetric score received by the article were 44.6 (0-475) and 19.2 (0-665) respectively. Majority of the articles contained at least one citation (98.3%) and altmetric score (98.2%). In regression analysis, citation count was significantly associated with the journal [Annals of Surgery (IRR= 1.93), JAMA surgery (IRR= 1.76)] and non-funded research (IRR= 0.83). The altmetric score was significantly associated with the country of the corresponding author (US) (IRR= 1.3), study subtopic, journal [JAMA surgery (IRR= 2.33)], non-funded (IRR= 0.74) and non-open-access publication (IRR= 0.44).

Conclusion: Article metrics were found to be associated with specific study subtopics, country of the corresponding author, funding, open-access publication and the journal. These results might help editors, reviewers and authors to produce, review and publish more impactful studies. A similar study in the future may help to better understand the changing dynamics of academic publishing.

Objectives: The aim of this study was to investigate the surgical treatment methods and outcomes of difficult duodenal defects due to perforation.

Material and methods: Data of patients who had undergone surgery for difficult duodenal defect between January 2012 and November 2022 were collected. Duodenal defect size of 2 cm or more was defined as difficult duodenal defect. Characteristics of the patients, the etiology of perforation, American Society of Anesthesiology (ASA) scores, Mannheim peritonitis index (MPI), surgical treatment, need for re-operation, and morbidity and mortality were evaluated.

Results: Nineteen patients were detected. Etiology was peptic ulcer perforation in 12 (63.1%) patients, aortaduodenal fistula in 2 (10.5%), tumor implant in 2 (10.5%), cholecystoduodenal fistula in 1 (5.2%), endoscopic retrograde cholangio pancreatography (ERCP) in 1 (5.2%), and cholecystectomy related injury in 1 (5.2%) patient. The first surgical procedure was duodenoraphy + omentopexy in 8 (42.1%), Graham repair in 5 (26.3%), duodenal segment 3-4 resection and Roux-en-Y side to side duodenojejunostomy in 4 (21.0%), Roux-en-Y side to side duodenojejunostomy in 1 (0.5%), and 1 (0.5%) subtotal gastrectomy + duodenum 1^st part resection + Roux-en-Y gastroenterostomy, cholecystectomy and external biliary drainage via cystic duct. Four patients who had previously undergone Graham repair (3) and duodenoraphy + omentopexy (1) required salvage surgery. As a salvage surgery; 1 end-to-side and 3 side-to-side Roux-en-Y duodenojejunostomies were performed. Overall, mortality occurred in 6 (31.6%) patients. High ASA score and MPI were considered as significant risk factors for mortality (p= 0.015, p= 0.002).

Conclusion: Primary repair techniques can be used in the surgical treatment of difficult duodenal defects when peritonitis is not severe and tensionfree repair is possible. Otherwise, duodenojejunostomy may be preferred as a fast, easy, and safe technique for both initial and salvage surgeries.

Objectives: Anastomotic leaks are the most feared complications after surgery in patients with Crohn's disease. Identifying associated risk factors is crucial for prevention. We aimed to evaluate possible risk factors for anastomotic complications in our case series.

Material and methods: This was a single-center, retrospective, observational study. Eighty-six patients who underwent intestinal resection due to Crohn's disease at the Department of General Surgery, Marmara University, Faculty of Medicine, from 2015 to 2023 were enrolled. Adult patients of either sex who are over 18 years old were included. Cases, where the anastomosis was defunctioned with a proximal diverting ileostomy or colostomy were excluded from the study.

Results: The mean (StD) age was 34.8 (14.4) years, and 50 patients (58.1%) were male. Twenty-five patients had post-operative complications (29.1%), and 10 of them (11.6%) were above grade three according to the Clavien-Dindo classification. Anastomotic leakage was observed in two, intra-abdominal collection in two, sepsis in two, enterocutaneous fistula in three, and ileus in the remaining one. While the albumin value <3 gr/dL (OR 5.15, p<0.03) and pre-operative medical treatment (OR= 4.79; p= 0.05) were associated with higher odds of post-operative overall complications, only hypoalbuminemia 3 g/dL (OR= 14.3; p= 0.04) was associated with a higher probability of post-operative anastomotic/septic complications.

Conclusion: In patients with pre-operative hypoalbuminemia, temporary stoma creation should be considered due to the potential increased risk of high anastomotic complications. The medical treatments should be discontinued in the pre-operative period due to the increased risk of complications.

Objectives: Recurrent pyogenic cholangitis (RPC) and ascariasis are prevalent in eastern India. Exact pathogenesis of RPC is still a matter of controversy. Hepatobiliary Ascaris infestation has been considered one of the causative factors in Eastern Asia, but conclusive evidence from India is lacking. RPC is associated with multi-drug-resistant (MDR) bacteria, which is a significant source of morbidity and mortality. This study aimed to assess the role of hepatobiliary ascariasis in pathogenesis of RPC and to study microbial profile and their implications in managing RPC patients.

Material and methods: Consecutive patients with biliary stones who underwent surgery between March 2020 and December 2021 in a tertiary centre in eastern India were divided into RPC and non-RPC groups. Surgically retrieved samples of bile and biliary stones were sent for bacterial culture and microscopic and histopathological examination to identify the evidence of ascariasis in both groups and to study the microbial profile in RPC group.

Results: Eight out of 54 patients (14.8%) in the RPC group had evidence of hepatobiliary ascariasis. None of the patients in non-RPC group showed evidence of ascariasis. Klebsiella was the most common bacterial pathogen on bile culture, and 79% of bacterial isolates were MDR pathogens. Carbapenem group of antibiotics showed the highest sensitivity (66.6%) against bacterial culture growth in RPC patients.

Conclusion: This study showed a higher prevalence of hepatobiliary ascariasis in patients with RPC, but a conclusive etiological role is still lacking. RPC is associated with high incidence of MDR bacteria. Carbapenems may be considered the empirical antibiotic of choice in RPC.

Objectives: The inferior vena cava (IVC) is one of the most frequent injured intra-abdominal vessels and its treatment requires prompt action. Despite advances in reanimation in last decades, there has not been proportional improvement in IVC mortality. This report aims to discuss the mortality predictive factors including the adherence to balanced reanimation and damage control surgery (DCS) in daily trauma assistance, their repercussions on outcomes, comparing our institution outcomes to literature.

Material and methods: A retrospective design analysis was made through database records of trauma patients at Clinic Hospital of University of Campinas, UNICAMP in order to investigate patients with IVC injuries, putting an emphasis on mortality predictive factors.

Results: Seventy-four patients were identified with IVC injury from January 1990 to August 2017. Predominant mechanism was penetrating with 87.8% (76.3% gunshot). On arrival, 37.8% of all of the victims were hypotensive, and ISS median was 24.5. Regarding location of IVC, 68.5% were infrarenal, 12.2% were suprarenal, 18.9% retrohepatic. Simple repair was performed in 60.8%. Ligation was carried out in 27% and atriocaval shunt was performed in 4.1%. There was not enough time for specific procedure in 8.1%. Associated intra-abdominal injuries were present in 97.3%, and the mean of transfusional requirements was 9.1 ± 6.9 for packed red blood cells. Overall mortality rate was 52.7%, with a mortality rate for infrarenal injuries being 39.2%. Damage control surgery was adopted in 33.8%, with 68% mortality.

Conclusion: A solid comprehension of shock reanimation has progressively been disseminated; however, trauma care professionals must assure that they are being applied with balanced reanimation and DCS.

Objectives: Gastrectomy for cancer is a technically demanding surgery and anastomotic leak is an important complication of this surgery. This study aimed to identify the factors associated with anastomotic leak following gastrectomy in gastric cancer patients and its long-term effect on outcomes.

Material and methods: This is an ambispective study of 181 patients who underwent curative gastrectomy for gastric adenocarcinoma over 13 years, at our institution. Groups with and without anastomotic leak were compared using the Mann-Whitney U test (continuous variables) and Chi-square test (categorical variables). A multivariable analysis was performed to determine the factors associated with anastomotic leak.

Results: Out of the 181 patients who underwent curative gastrectomy, 12 (6.6%) patients experienced anastomotic leak. A multivariable analysis revealed that younger age, presence of comorbidities, hypoalbuminemia, tumor location in the proximal stomach, type of reconstruction, and positive margin status were associating factors for anastomotic leak. During a median follow-up of 34 months (ranging from 12 to 130), it was observed that 25 (18.3%) patients developed anastomotic stenosis, but it was not related to anastomotic leak. The incidence of post-operative pulmonary complications, administration of adjuvant therapy, recurrence rates, and mortality due to anastomotic leak did not significantly change. Moreover, neoadjuvant therapy did not increase the incidence of anastomotic leaks.

Conclusion: Factors like younger age, presence of comorbidities, hypoalbuminemia, tumor location in the proximal stomach, type of reconstruction, and positive margin status were associated with increased risk of anastomotic leak, which needs further studies to validate the findings. Thus, preoperative optimization and resection with adequate margins may be of utmost importance in preventing anastomotic leaks.

Objectives: Laparoscopic-assisted pancreaticoduodenectomy (LAPD) is being performed in several centers worldwide. The proportion of minimally invasive pancreaticoduodenectomy for periampullary carcinoma (PAC) has recently increased, owing to its potential benefits. However, the safety and feasibility of LAPD have not yet been standardized. In this study, it was aimed to report our experience with LAPD in 50 patients.

Material and methods: Fifty patients with resectable PAC who underwent LAPD between June 2021 and August 2023 were retrospectively analyzed.

Results: Mean age of the study group was 49.9 ± 12 years, and most were females (54%). Ampullary carcinoma was the most common type (58%). Mean operative time and estimated blood loss were 460 ± 40 minutes and 426 ± 156 mL, respectively. Four patients had suspected portal vein involvement, and two patients had hemorrhage during uncinate process dissection, resulting in conversion to open surgery. Severe post-operative morbidity was noted in 13 (26%) patients. Following surgery, Grade B post-operative pancreatic fistula was present in 26% of patients, whereas Grade B and C delayed gastric emptying was present in 18% and 2% of patients, respectively. Mean hospital stay was 9.4 ± 2.8 days. Mean number of lymph nodes harvested was 13.4 ± 4. All patients underwent R0 resection, and no mortality was noted during the 30-day follow-up period.

Conclusion: LAPD is a feasible procedure for resectable PAC offering good oncological outcomes and minimal complications. It can be performed effectively by experienced surgeons in specialized centers.