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Subcutaneous radiofrequency: prospective pilot study on safety and efficacy in face chrono-ageing treatment 皮下射频:面部衰老治疗安全性和有效性的前瞻性先导研究
Pub Date : 2021-01-01 DOI: 10.15406/jdc.2021.05.00184
B. Fanelli
Objective: to evaluate the efficacy, safety and tolerance of the face aging treatment using subcutaneous radiofrequency in patients with mild, moderate e severe ptosis of the middle face. Material and methods: prospective data from patients treated with subcutaneous radiofrequency. Patients underwent two treatment session carried out by the same surgeon. The principal efficacy criterion was the assessment of depth reduction of the naso-labial fold and malar prominence’s restoration after 3 and 6 months, the evaluation of the Global Aesthetic Improvement Scale by the patients and an outside procedure surgeon was the second criteria. Safety and tolerance were evaluated through observed side effects. Result: A total of 30 patients, 27 women and 3 men with a mean age of 53 years underwent subcutaneous radiofrequency procedure. Depth’s reduction of the naso-labial fold and malar prominence’s restoration was observed in the majority of all case, associated to the patient e medical satisfaction. Transitory adverse effects, commonly for cosmetic procedure e.g erythema, edema was not observed. One patient had post procedure hematoma. No serious adverse effects such as burning or scars were reported. Conclusion: This prospective pilot data confirmed that subcutaneous radiofrequency is a safe and effective in improvement in skin laxity. Patients’ satisfaction was high. Although this treatment cannot substitute surgical procedure, it might prolong the time to the first surgical facial lift. Further confirmation investigation should be performed.
目的:评价皮下射频治疗中脸轻、中、重度上睑下垂面部老化的疗效、安全性和耐受性。材料和方法:来自皮下射频治疗患者的前瞻性数据。患者接受了由同一名外科医生进行的两次治疗。主要疗效评价标准为术后3个月和6个月鼻唇襞深度缩小和颧突修复情况,其次为患者和外手术医师对整体美观改善量表的评价。通过观察副作用来评价安全性和耐受性。结果:共有30例患者接受了皮下射频治疗,其中27例女性,3例男性,平均年龄53岁。大多数病例的鼻唇沟深度复位和颧突修复均与患者的医疗满意度相关。短暂的不良反应,常见的美容程序,如红斑,水肿未观察到。1例患者术后出现血肿。没有严重的不良反应,如烧伤或疤痕的报道。结论:这一前瞻性试验数据证实了皮下射频是一种安全有效的改善皮肤松弛的方法。患者满意度高。虽然这种治疗不能代替外科手术,但它可能会延长第一次手术面部提升的时间。应进行进一步的确认调查。
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引用次数: 2
Acquired lymphangioma circumscriptum of the vulva treated with ablative radiofrequency 射频消融治疗外阴获得性淋巴管瘤
Pub Date : 2021-01-01 DOI: 10.15406/jdc.2021.05.00192
J. Vukičević
(LC) is a benign disorder involving the lymphatic system of skin and subcutaneous tissue. A case of acquired LC of the vulva in a57-year-old woman with a 10 -15 year history of lymphoedema of the left leg and vulvar lesions (vesicles and papulovesicles) following cervical cancer operation and subsequent radio therapy is presented. The patient was treated with ablative radiofrequency and was free of lesions for 6 months.
(LC)是一种涉及皮肤和皮下组织淋巴系统的良性疾病。本文报道一位57岁女性,在宫颈癌手术和放疗后,左腿淋巴水肿和外阴病变(囊泡和丘疹囊泡)有10 -15年的历史,并发外阴获得性LC。患者接受射频消融治疗,6个月无病变。
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引用次数: 0
Satellite glial cells of the peripheral nervous system 周围神经系统的卫星胶质细胞
Pub Date : 2021-01-01 DOI: 10.15406/jdc.2021.05.00181
D. Smith
receptors and ion channels in both nerve terminals. Activity in somata dynamically contributes to nerve signaling to dorsal horn cells. Non-neuronal cells also affect neuronal activity through glial-neuron interaction. Somata of sensory neurons do not form synaptic contacts with one another in the ganglia, instead they are enveloped by satellite glial cells (SGCs).
两个神经末梢的受体和离子通道。躯体活动动态地向背角细胞传递神经信号。非神经元细胞也通过神经胶质-神经元相互作用影响神经元活动。在神经节中,感觉神经元的胞体彼此之间不形成突触接触,而是被卫星胶质细胞(sgc)包裹。
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引用次数: 0
Grover’s disease: a rare bullous dermatosis spontaneously regressing 格罗弗病:一种罕见的可自行消退的大疱性皮肤病
Pub Date : 2021-01-01 DOI: 10.15406/jdc.2021.05.00187
Sara Bouadella
Grover's diseaseis an itchy acantholytic disorder occurring on the trunk of middle-aged men. It is a transient dermatosis of unknown cause manifesting clinically as a papular skin eruption located usually on the anterior chest and abdomen and histologically with dyskeratosis and acantholysis. This disease has occasionally been reported in patients with chronic renal failure, some infections, hematological malignancies, and many other anomalies. We report herein a new case of Grover's disease that developed in a female patient after a fever episode.
格罗弗氏病是发生在中年男性躯干上的一种发痒的棘皮溶解性疾病。它是一种原因不明的短暂性皮肤病,临床表现为丘疹性皮肤疹,通常位于前胸和腹部,组织学上表现为角化不良和棘层松解。此病偶见于慢性肾功能衰竭、某些感染、血液恶性肿瘤和许多其他异常患者。我们在此报告一个新的格罗弗病的情况下,在发烧发作后发展的女性患者。
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引用次数: 0
Alopecia types, current and future treatment 脱发类型,目前和未来的治疗
Pub Date : 2021-01-01 DOI: 10.15406/jdc.2021.05.00190
H. Rambwawasvika
There are diverse types of alopecia and each call for a specific treatment. Regrettably there is no curative solution to the problem of alopecia as most drugs target its management. The purpose of the review is to explore the different types of alopecia and how each affect hair appearance and growth. The review begins by describing hair structure and hair physiological changes during life progression. A detailed description of conventional medication prescribed for alopecia and associated adverse effects are also pronounced in this review. Both approved (minoxidil and finasteride) and unapproved medications indicated for the condition are discussed to expose voids, which need to be filled by future drug development. The review also discusses the prospective future therapies of alopecia as directed by current research and technological advancement.
脱发有多种类型,每种类型都需要特定的治疗方法。遗憾的是,没有根治脱发的方法,因为大多数药物都针对其管理。这篇综述的目的是探讨不同类型的脱发以及每一种脱发对头发外观和生长的影响。回顾开始描述头发结构和头发生理变化在生命进程。详细描述了常规药物处方脱发和相关的不良反应也明显在这篇综述。已批准的(米诺地尔和非那雄胺)和未批准的针对该病症的药物都被讨论以暴露出空白,这些空白需要通过未来的药物开发来填补。本文还根据目前的研究和技术进步讨论了未来治疗脱发的方法。
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引用次数: 9
Bilateral dyshidrosiform pemphigus vulgaris: an unusual clinical presentation 双侧寻常性汗湿性天疱疮:一种不寻常的临床表现
Pub Date : 2021-01-01 DOI: 10.15406/JDC.2021.05.00179
A. Khouna
months (Figure 1). Nail anomalies of the toes were also noted, like perionyxis and onychodystrophy. He reported having chronic oral and genital erosions that have progressed over the past 10 years in flareups and incomplete remissions. There was no lesion elsewhere in the body. Two weeks later, he developed several annular bullous necrotic lesions on the back with some pseudococards lesions (Figure 2) with extension of oral and genital erosions (Figure 3).
月(图1)。脚趾指甲异常也被注意到,如甲周炎和甲营养不良。他报告有慢性口腔和生殖器糜烂,在过去的10年里以突发和不完全缓解的方式进展。身体其他部位没有病变。两周后,患者背部出现几个环形大疱性坏死灶,伴假性牙卡病变(图2),口腔和生殖器糜烂延伸(图3)。
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引用次数: 0
Secondary alopecia neoplastica – the first metastasis of the breast cancer 继发性肿瘤性脱发-乳腺癌的第一次转移
Pub Date : 2021-01-01 DOI: 10.15406/jdc.2021.05.00194
J. Vukicevic
On examination, in parietal region two alopecic plaques, measuring 4x5cm i 2x2cm, slightly sclerotic, erythematous, shiny, with rare crusts and telangiectasia were seen (Figure 1a). Routine laboratory analyses and tumor markers( CA 128, CA 15-3, CEA ) were within normal limits, chest x-ray and ultrasound of the abdomen showed no pathological lesions. Histopathology of the by opted skin lesion revealed atypical cells that form infiltrative cords, small lobules and ducts throughout the dermis. These cells exhibited marked pleomorphism with high nuclear/ cytoplasmic ratio (Figure 2). Metastatic breast carcinoma was confirmed.
检查时,在顶骨区可见2个脱落斑块,尺寸为4x5cm至2x2cm,轻度硬化,红斑,有光泽,罕见结痂和毛细血管扩张(图1a)。实验室常规分析及肿瘤标志物(ca128、ca15 -3、CEA)正常,胸片及腹部超声未见病理病变。皮肤病变的组织病理学显示非典型细胞形成浸润性索,小小叶和贯穿真皮层的导管。这些细胞表现出明显的多形性,核质比高(图2)。证实转移性乳腺癌。
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引用次数: 0
Lip and perioral assessment scale – a tool that can improve your practice 嘴唇和口腔评估量表-一个可以提高你的实践的工具
Pub Date : 2021-01-01 DOI: 10.15406/jdc.2021.05.00191
L. Avelar
Background: The lips and perioral region are a highly dynamic anatomic area of the face and its anatomy and measurements will vary from patient to patient. In many years of clinical practice and as trainers for other injectors we have noticed that the assessment of this region is also very variable regardless of the experience of the injector. Objectives: The goal of this article is to provide a tool for assessment of the lower face and perioral area in other to simplify cosmetic treatments and help injectors identify what needs to be addressed in each patient. Methods: Over the last few years, weanalyzed the most common concerns of every patient presenting for treatment of the lips and perioral area and the most frequent areas addressed in the treatment of the lower face, and organized them into a tool that was able to systematize the different levels of attention needed in each particular area, guiding injectors towards a better final result. As trainers for other injectors, we also analyzed the most difficult aspects of the perioral assessment and simplified them into this tool that can help even novice injectors to do the correct diagnosis and therefore achieve better results while treating the perioral area. Conclusions: We believe that this tool will help both experienced and young injectors in the assessment of the lips and perioral area prior to treatment and in doing so, will provide a better outcome and cosmetic result.
背景:嘴唇和口周区域是面部高度动态的解剖区域,其解剖结构和测量将因患者而异。在多年的临床实践中,作为其他注射者的培训师,我们注意到,无论注射者的经验如何,对该区域的评估也是非常多变的。目的:这篇文章的目的是提供一种工具来评估下面部和口腔周围区域,以简化美容治疗,并帮助注射人员确定每个患者需要解决的问题。方法:在过去的几年里,我们分析了每一个病人最常见的问题,唇部和口腔周围的治疗和最常见的区域处理的下脸,并将它们组织成一个工具,能够系统的不同程度的关注需要在每个特定的区域,指导注射器走向更好的最终结果。作为其他注射人员的培训师,我们也分析了口腔周围评估中最困难的方面,并将其简化为这个工具,即使是新手注射人员也可以帮助他们做出正确的诊断,从而在治疗口腔周围区域时取得更好的效果。结论:我们相信该工具将帮助有经验的和年轻的注射者在治疗前评估嘴唇和口腔周围区域,这样做将提供更好的结果和美容效果。
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引用次数: 1
Mandible: evaluation of its morphology, aging process and sexual dimorphism for aesthetic treatment purpose 下颌骨:形态学、老化过程及两性二态性的评价
Pub Date : 2021-01-01 DOI: 10.15406/jdc.2021.05.00182
L. Avelar
The mandible is the most important bone structure of the facial makeup. Its morphology differs with respect to genetic factors, sexual dimorphism, and age. Among its particular characteristics is the ability to adapt with its counterpart, the base of the skull, conferring a dynamic quality of this bone, by the mechanism of constant remodeling. In order to understand the involvement of the mandible in the evaluation of the lower third of the face, a fractional analysis of its parts is necessary considering morphological parameters of the mandibular angle. The purpose of this study is to demonstrate the importance of the mandible as an instrument in the analysis of the lower third of the face, allowing the accomplishment of aesthetic treatment, respecting the individual characteristics.
下颌骨是面部最重要的骨骼结构。其形态因遗传因素、两性二态性和年龄的不同而不同。它的特殊特征之一是能够适应它的对应物,头骨的底部,通过不断重塑的机制赋予该骨的动态质量。为了了解下颌骨在面部下三分之一的评估中的作用,考虑到下颌骨角的形态学参数,对其部分进行分数分析是必要的。本研究的目的是证明下颌骨作为分析面部下三分之一的工具的重要性,允许完成美学治疗,尊重个体特征。
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引用次数: 5
Current trends of antibiotic resistance among human skin infections causing bacteria; a cross-sectional study 引起人类皮肤感染的细菌中抗生素耐药性的当前趋势;横断面研究
Pub Date : 2021-01-01 DOI: 10.15406/jdc.2021.05.00189
M. Khan
Objectives: To determine the current status of skin infections causing bacteria and their pattern of resistance to widely used antibiotics among the physician referred patients in district Peshawar, Pakistan. Materials and methods: A cross-sectional study of 164 pus samples from diseased patients, referred by physicians was done for a period from February 2020 to January 2021 at Department of Microbiology, Complex medical laboratory and Research center, Peshawar, Pakistan. Results: The bacterial growth were obtained in 88 pus samples. Among these isolated bacterial species Escherichia coli was the most prevalent pathogen, present in (46%), Staphylococcus aureus (39%), Proteus species (11%), Klebseilla species (2%) and Pseudomonas aerugenosa (2%), respectively. Among the tested antibiotics resistance wise E.coli was highly resistance to Ampicillin (92.5%), S. Aureus to Levofloxacin (91.1%), Proteus spp .to Doxycycline (90%), Klebsiella spp. to Meropenem (100%), Amoxicillin (100%) and P. aeruginosato Aztreonam (100%), Doxycycline (100%), respectively.Sensitivity wise E.coli was highly sensitive to Amikacin (90%), S. aureus to Meropenem (91.1%) and Doxycycline (91.1%),Proteus spp. to Meropenem (100%), Klebsiella spp. to Ciprofloxacin (100%), Cefotaxime (100%), Aztreonam (100%) and Doxycycline (100%), P. aeruginosa to Amikacin (100%), Meropenem(100%), Ciprofloxacin (100%), Gentamicin (100%), Cefotaxime (100%), Ceftriaxone (100%), Ampicillin (100%) and Cefotaxime (100%), respectively. Conclusion: The most prevalent skin infections causing bacteria was E.coli, followed by S. aureus, Proteus spp., Klebseilla spp. and P. aerugenosa, respectively. The antibiogram provides adequate knowledge of effective therapeutic agents for the treatment strategies of skin infections.
目的:了解巴基斯坦白沙瓦地区医师转诊患者皮肤感染病原菌现状及其对常用抗生素的耐药模式。材料和方法:在2020年2月至2021年1月期间,在巴基斯坦白沙瓦复杂医学实验室和研究中心微生物学系对医生转诊的164例患病患者的脓样本进行了横断面研究。结果:88份脓液标本均有细菌生长。在这些分离的细菌种类中,大肠杆菌是最常见的病原体,分别存在于金黄色葡萄球菌(39%)、变形杆菌(11%)、克雷伯菌(2%)和绿脓杆菌(2%)中。其中,大肠杆菌对氨苄西林(92.5%)、金黄色葡萄球菌对左氧氟沙星(91.1%)、变形杆菌对强力西环素(90%)、克雷伯菌对美罗培南(100%)、阿莫西林(100%)和铜绿假单胞菌对氨曲南(100%)、强力西环素(100%)的耐药程度最高。敏感性方面大肠杆菌对阿米卡星(90%)高度敏感,金黄色葡萄球菌对美罗培南(91.1%)和多西环素(91.1%)高度敏感,变形杆菌对美罗培南(100%)高度敏感,克雷伯菌对环丙沙星(100%)、头孢噻肟(100%)、氨曲南(100%)和多西环素(100%)高度敏感,铜绿假单胞菌对阿米卡星(100%)、美罗培南(100%)、环丙沙星(100%)、庆大霉素(100%)、头孢噻肟(100%)、头孢曲松(100%)、氨苄西林(100%)和头孢噻肟(100%)高度敏感。结论:引起皮肤感染的细菌以大肠杆菌最多,其次为金黄色葡萄球菌、变形杆菌、克雷伯菌和铜绿假单胞菌。抗生素谱为皮肤感染的治疗策略提供了有效治疗药物的充分知识。
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引用次数: 2
期刊
Ukrainian Journal of Dermatology, Venerology, Cosmetology
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