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Longitudinal-cross-linking method of the sternum osteosynthesis – an additional way for the prophylaxis of deep sternal infection in cardiac surgery patients 胸骨纵向交联法——预防心脏手术患者胸骨深部感染的另一种方法
Q4 Medicine Pub Date : 2020-08-03 DOI: 10.24884/0042-4625-2020-179-3-25-32
D. Kuznetsov, A. Gevorgyan, V. V. Novokshenov, K. Mikhailov, A. V. Kryukov, S. Khokhlunov
The OBJECTIVE of the study was to compare the results of using the longitudinal – cross-linking method of sternum osteosynthesis with other methods (single wire stitches, 8-shaped wire stitches) for cardiosurgery patients.METHODS AND MATERIALS. The study included 3,150 patients, which were operated on in Samara cardiology dispensary named after V. P. Poliakov from 2012 to 2018. Patients were divided into 2 groups. Group 1 (1397 patients, operated on from 2012 to 2014) used single wire stitches or 8-shaped wire stitches for sternum osteosynthesis. Group 2 (1753 patients, operated from 2015 to 2018) used the longitudinal -cross-linking method of sternum osteosynthesis. The incidence of instability of the sternum without infection, superficial postoperative wound infection, deep sternal infection and hospital mortality were evaluated.RESULTS. Groups (1–68 % of men, average age (59.4±9,9) years; 2–68 % of men, average age 62.3±8.5) were significantly different in obesity patients (25.6 & 29.3 %, p=0.02), amount of smokers (50.5 & 64.2 %, p<0.001) and amount of urgent cases (3 & 10 %, p<0.001). The incidence of sternal instability without infection was less in group 2 (0.64 & 0.29 %; OR, 2.29; 95 % CI, 0.76 to 6.8; p=0.1). The amount of deep sternal infection was significant less in group 2 (1.6 & 0.6 %; OR, 2.53; 95 % CI, 1.2 to 5.2; p=0.009). The hospital mortality was 3.9 % in group 1 and 2.96 % in group 2 (OR, 1.34; 95 % CI, 0.9 to 1.9; p=0.1).CONCLUSION. The longitudinal-cross-linking method of sternum osteosynthesis is the available method that can significantly reduce the incidence of deep sternal infection in cardiosurgery.
本研究的目的是比较胸骨纵向交联法与其他方法(单线针、8形线针)在心脏外科患者中的应用效果。方法和材料。该研究包括3150名患者,这些患者于2012年至2018年在以V. P. Poliakov命名的萨马拉心脏病学药房接受手术。患者分为两组。组1(2012 - 2014年手术1397例)采用单线针或8形线缝合胸骨。第二组1753例,2015 - 2018年行胸骨纵向交联成骨术。观察两组无感染胸骨不稳发生率、术后浅表伤口感染发生率、胸骨深部感染发生率及住院死亡率。组(1 ~ 68%)男性,平均年龄(59.4±9.9)岁;肥胖患者(25.6% & 29.3%,p=0.02)、吸烟人数(50.5% & 64.2%,p<0.001)、急症人数(3% & 10%,p<0.001)与男性(2 ~ 68%,平均年龄62.3±8.5)有显著性差异。2组无感染胸骨不稳发生率较低(0.64% & 0.29%;或者,2.29;95% CI, 0.76 - 6.8;p = 0.1)。2组胸骨深部感染发生率明显低于对照组(1.6%、0.6%;或者,2.53;95% CI, 1.2 - 5.2;p = 0.009)。组1住院死亡率为3.9%,组2住院死亡率为2.96% (OR, 1.34;95% CI, 0.9 ~ 1.9;.CONCLUSION p = 0.1)。胸骨纵向交联法是目前可以显著降低心脏外科胸骨深部感染发生率的可行方法。
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引用次数: 0
Application of the original method of intra-operative electrophysiological stimulation of recurrent laryngeal nerve with surgical interventions on the neck organs 术中电生理刺激喉返神经的原始方法与颈部器官手术干预的应用
Q4 Medicine Pub Date : 2020-08-03 DOI: 10.24884/0042-4625-2020-179-3-19-24
А. С. Толстокоров, С. Н. Котов, Г. А. Манахов, Российской Федерации, Yury V. Kovalenko, Aleksandr S. Tolstokorov, Sergey N. Kotov, German A. Manakhov, Elena N. Kurochkina
The OBJECTIVE was the reduction in the frequency of specific complications of surgical treatment of patients with pathology of the thyroid and parathyroid glands using the original method of monitoring the neuro-functional activity of the recurrent laryngeal nerve.METHODS AND MATERIALS. The research was conducted in two stages. At the first stage, the object of the topographic-anatomical study was 50 male and female corpses. The research, based on the fixed material, was focused upon the study of the anatomic special features of recurrent laryngeal nerves, their relations with neighboring structures, the study of peculiarities of recurrent laryngeal nerve syntopy and its neighboring structures to find the least traumatic way of incision during electroneurophysiological monitoring of activity. At the second stage, the object of the study was 60 patients with a benign pathology of the thyroid gland, who were operated on with the use of the original method of intra-operational visualization and control method over neuro-functional activity of recurrent laryngeal nerve.RESULTS. The frequency of the three different variants of topographic-anatomical position of recurrent laryngeal nerve depends on the side of the body. The safest, stable and the fastest one to be found is the left recurrent laryngeal nerve. Postoperative unilateral paresis of the larynx, diagnosed in 4 of 60 patients, is regarded as postischemic. Two-sided paresis of the larynx was diagnosed in 1 patient.CONCLUSION. This method allows to minimize the development of severe intraoperative complications, to reduce the frequency of postoperative paralysis and paresis of the larynx. Intra-operative visualization of recurrent laryngeal nerves is especially necessary during the repeated surgeries with postoperative scar transformations with wrong syntopy of neck organs and vascular-nerve structures, which makes it possible to minimize the number of postoperative paralyses and paresis of larynx and to get positive effect without carrying out the intubation of trachea among patients with postoperative paralysis of larynx or stenosis, and to avoid more serious damage of larynx or trachea in case of intubation.
目的是通过监测喉返神经的神经功能活动的原始方法,减少甲状腺和甲状旁腺病变患者手术治疗的特定并发症的频率。方法和材料。研究分两个阶段进行。第一阶段,地形解剖研究对象为50具男女尸体。本研究在固定材料的基础上,重点研究喉返神经的解剖特点及其与邻近结构的关系,研究喉返神经的神经突触及其邻近结构的特点,寻找神经电生理活动监测中创伤最小的切口方式。第二阶段,研究对象为60例甲状腺良性病变患者,采用独创的术中显像法和喉返神经功能活动控制法进行手术。喉返神经的地形解剖位置的三种不同变体的频率取决于身体的侧面。最安全,最稳定,最快找到的是左喉返神经。术后单侧喉瘫,诊断为60例患者中的4例,被认为是术后。诊断为双侧喉瘫1例。这种方法可以最大限度地减少严重术中并发症的发生,减少术后麻痹和喉瘫的发生频率。术中喉返神经的显像对术后瘢痕转化、颈部脏器及血管神经结构错误的重复手术尤为必要,可使术后喉麻痹或喉狭窄患者在不进行气管插管的情况下,最大限度地减少术后麻痹、喉瘫的发生,取得积极效果。避免在插管时对喉部或气管造成更严重的损伤。
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引用次数: 0
Clinic, diagnostics, treatment and results of acute lung accesses in HIV-infected patients hiv感染者急性肺通道的临床、诊断、治疗和结果
Q4 Medicine Pub Date : 2020-08-03 DOI: 10.24884/0042-4625-2020-179-3-69-74
P. Ionov, А. V. Elikin, I. Deinega, G. Yakovlev
The OBJECTIVE was to study the course and results of treatment of lung abscesses in HIV-infected patients.METHODS AND MATERIALS. We analyzed the case histories of 199 patients with lung abscesses who treated in the Department of thoracic surgery of St. Petersburg Pokrovskaya Municipal Hospital in the period from 2012 to 2018. The 1st group included 121 HIV-infected patients, and the 2nd group – 78 patients with HIV-negative status.RESULTS. Patients from the 1st group were younger than patients from the 2nd group (p <0.05). Lung abscesses without sequestration were detected in 105 (86.8 %) patients in the 1st I group and 65 (83.3 %) in the 2nd group. Lung abscesses with sequestration (gangrenous abscesses) was diagnosed in 16 (13.2 %) HIV-infected and 13 (16.7 %) uninfected patients. There were no differences between surgical methods of treatment and outcomes (p>0.05). The mortality rate in the 1st group was 9.1 %, and in the 2nd – 12.8 %.CONCLUSION. General surgical methods for treating lung abscess are equally effective in patients with HIV-negative status and HIV-positive status. Lung abscesses in HIV-positive and HIV-negative patients have a similar etiology, clinical symptomatology, courses and outcome.
目的:探讨hiv感染患者肺脓肿的治疗过程和结果。方法和材料。我们分析了2012 - 2018年在圣彼得堡波克罗夫斯卡亚市属医院胸外科治疗的199例肺脓肿患者的病例史。第一组121例hiv感染者,第二组78例hiv阴性患者。第一组患者年龄明显小于第二组(p < 0.05)。第一组病死率为9.1%,第二组病死率为12.8%。治疗肺脓肿的一般手术方法对hiv阴性和hiv阳性患者同样有效。hiv阳性和hiv阴性患者的肺脓肿具有相似的病因、临床症状、病程和结局。
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引用次数: 4
Problems of performing coronary artery bypass grafting after preliminary stenting of coronary arteries due to acute coronary syndrome (review of literature) 急性冠脉综合征冠状动脉初步支架置入术后行冠状动脉搭桥术的问题(文献复习)
Q4 Medicine Pub Date : 2020-08-03 DOI: 10.24884/0042-4625-2020-179-3-100-106
Р. Бигашев, Н. Н. Шихвердиев, С. Пелешок, A. R. Bigashev, N. N. Shikhverdiev, A. Peleshok, V. Soroka
The objective of this article was to analyze current researches on the peculiarities of performing coronary artery bypass grafting in patients who primarily underwent intraluminal angioplasty and stenting due to acute coronary syndrome. Despite the priority of stenting in patients with acute coronary syndrome (ACS), there is still a significant number of unresolved issues in this category of patients, especially when these patients, previously stenting due to ACS, undergo coronary artery bypass grafting due to a repeated ACS case. The tactics of management and preparation of patients who were admitted for repeated CABG after preliminary stenting are still not clear, and therefore, a significant number of unresolved issues remains when performing CABG against the background of repeated ACS cases with a previously compromised vascular bed and the presence of chronic inflammation in the coronary arteries. Questions about the perioperative and postoperative complications in this category of patients remain open. We analyzed the latest works and researches about that problem using such systems as NLM, Google Scholar and Elibrary. Due to the current situation of mass use of stenting, a number of questions remain open (the time of cancellation of double disaggregation therapy, the need for shunting the previously stented vessel, the possibility of performing a combined method of treatment for ACS). There is a very little information on the need to bypass the previously stented coronary artery at an earlier date than indicated in the European recommendations.
本文的目的是分析目前对急性冠状动脉综合征患者行腔内血管成形术和支架植入术的特点的研究。尽管急性冠脉综合征(ACS)患者优先接受支架植入术,但在这类患者中仍有大量未解决的问题,特别是当这些患者先前因ACS而接受支架植入术,由于反复发生ACS而接受冠状动脉旁路移植术时。初步支架植入术后再次进行冠脉搭桥的患者的处理和准备策略尚不清楚,因此,在血管床先前受损且冠状动脉存在慢性炎症的重复ACS病例的背景下进行冠脉搭桥时,仍有大量未解决的问题。关于这类患者围手术期和术后并发症的问题仍未解决。本文运用NLM、b谷歌Scholar、library等系统对该问题的最新研究成果进行了分析。由于目前支架的大量使用,许多问题仍未解决(取消双解体治疗的时间,先前支架血管的分流需要,对ACS进行联合治疗的可能性)。关于需要在比欧洲建议的更早的日期搭桥先前支架冠状动脉的信息很少。
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引用次数: 1
The role of defining the sentinel lymph node in the treatment of low-risk highly differentiated thyroid cancer (review of literature) 确定前哨淋巴结在低危高分化甲状腺癌治疗中的作用(文献综述)
Q4 Medicine Pub Date : 2020-08-03 DOI: 10.24884/0042-4625-2020-179-3-107-112
M. E. Boriskova, U. Farafonova, P. A. Pankova, M. A. Bykov, E. A. Ramazanova, N. S. Feshenko, A. Zakharenko, N. A. Yaitsky
The definition of a sentinel lymph node is a technique that appeared at the middle of the 20th century. For a number of malignant neoplasms, the definition of a sentinel lymph node is standard procedure, but for highly differentiated thyroid cancer, the data is conflicting. The role of prophylactic central compartment lymph node dissection in the clinical N0 stage is not established. Sentinel lymph node detection seems to be the possible way to reduce the risk of persistence and recurrence of highly differentiated thyroid cancer.
前哨淋巴结的定义是20世纪中期出现的一项技术。对于许多恶性肿瘤,前哨淋巴结的定义是标准的程序,但对于高度分化的甲状腺癌,数据是矛盾的。预防性中央室淋巴结清扫在临床N0期的作用尚未确定。前哨淋巴结检测似乎是降低高分化甲状腺癌持续和复发风险的可能途径。
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引用次数: 2
Features of mechanical jaundice course caused by complications of bile disease 胆汁疾病并发症所致机械性黄疸病程特点分析
Q4 Medicine Pub Date : 2020-08-03 DOI: 10.24884/0042-4625-2020-179-3-48-57
Б. С. Харитонов, В. Масляков, Е. Логвина, Vladimir E. Fedorov, B. S. Haritonov, V. V. Masljakov, O. Logvina, M. A. Naryzhnaja
The OBJECTIVE was improving the results of diagnostics and assessment of the severity of patients with mechanical jaundice (MJ) at various stages of its development.METHODS AND MATERIALS. The basis of clinical and laboratory research was the data of 537 patients who were admitted during the period from 2010 to 2019. Principles of separation at the stage of the course of mechanical jaundice of non-tumor Genesis.RESULTS. Analysis of clinical and laboratory studies showed characteristic signs of various complications of cholelithiasis, accompanied by mechanical jaundice. Then, on this basis, specific symptoms characteristic of each stage of mechanical jaundice of non-tumor Genesis were determined.CONCLUSION. The course of mechanical jaundice, which develops with complications of cholelithiasis, has a phase-stage character, beginning with extrahepatic cholestasis, then-joining hepatocytolysis and ending with cholangitis. Initially, cholestasis and cytolysis are functional, which is confirmed by biochemical tests, so these processes are labile and reversible. This makes it possible to effectively use biliary decompression methods and infusion therapy with detoxification during treatment. Cholangitis is characterized by destructive morphological manifestations, so it is verified by specific clinical symptoms and laboratory tests characteristic of inflammatory-septic reactions and progresses to sepsis. Differentiation of stages of mechanical jaundice allows to personify surgical and conservative treatment of such patients.
目的是改善机械性黄疸(MJ)不同发展阶段患者严重程度的诊断和评估结果。方法和材料。临床和实验室研究的依据是2010 - 2019年537例住院患者的数据。非肿瘤源性机械性黄疸病程阶段的分离原则。临床和实验室研究分析显示胆石症的各种并发症的特征性迹象,并伴有机械性黄疸。在此基础上,确定非肿瘤源性机械性黄疸各阶段的具体症状特征。机械性黄疸伴胆石症并发症发展,其病程具有阶段性特征,开始于肝外胆汁淤积,然后加入肝细胞溶解,最后以胆管炎结束。最初,胆汁淤积和细胞溶解是功能性的,生化试验证实了这一点,因此这些过程是不稳定和可逆的。这使得在治疗期间有效地使用胆道减压方法和输注解毒疗法成为可能。胆管炎以破坏性形态表现为特征,可通过特定的临床症状和以炎症-脓毒反应为特征的实验室检查加以证实,并进展为脓毒症。机械性黄疸分期的区分可以使此类患者的手术和保守治疗具体化。
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引用次数: 2
Treatment and prevention of the recurrence of liver echinococcosis 肝包虫病复发的治疗与预防
Q4 Medicine Pub Date : 2020-06-29 DOI: 10.24884/0042-4625-2020-179-2-26-32
R. T. Mejidov, R. Sultanova
The OBJECTIVE was to make the comparative assessment of surgical methods for the treatment and prevention of the recurrence of echinococcal liver disease, as well as to study negative and positive aspects of closed echinococcectomy in relation to recurrent efficacy.METHODS AND MATERIAL. 1072 cases (1358 cysts) of echinococcal liver disease were subjected to a retrospective analysis. The clinic performed radical (closed) echinococcectomy using high-tech resection devices on 258 patients, including ultrasound dissectors and destructors-aspirators for 105 patients (main group), other resection devices (LigaSure, an argon plasma scalpel) for patients (control group).RESULTS. Inpatient treatment of patients in the main group amounted to (9.4±2.1) days, in the control group – (11.6±1.7). Postoperative complications in the main group were observed at 4.6 % of patients, in the control group – 11.0 %. Relapse of the liver echinococcosis in the control group occurred in 2.3 % of cases, there were no relapses in the main group. The quality of life of patients in the main group was (73.5±1.8) points, in the control group – (72, 8±1.7) points. There were no lethal outcomes in both groups of patients.CONCLUSION. The most effective in the treatment and prevention of recurrence of echinococcal liver disease are closed methods of echinococcectomy: a cyst pericystectomy, liver resection. When we use ultrasound resection techniques for closed (radical) surgical interventions, intra- and postoperative complications are reduced and the immediate and long-term results of patients with liver echinococcosis are improved.
目的:对治疗和预防棘球蚴性肝病复发的手术方法进行比较评价,研究闭合性棘球蚴切除术的阴性和阳性方面与复发疗效的关系。方法和材料。本文对1072例包虫病(1358例包虫病)进行回顾性分析。采用高科技切除器械对258例患者行根治性(闭合性)棘球蚴切除术,其中超声解剖器和破坏-吸引器105例(主组),其他切除器械(LigaSure氩等离子手术刀)为对照组。治疗组患者住院时间为(9.4±2.1)天,对照组为(11.6±1.7)天。主组术后并发症发生率为4.6%,对照组为11.0%。对照组肝包虫病复发率为2.3%,主组无复发病例。治疗组患者生活质量得分为(73.5±1.8)分,对照组患者生活质量得分为-(72,8±1.7)分。两组患者均无致死性结局。治疗和预防棘球蚴性肝病复发最有效的方法是闭合性棘球蚴切除术:包囊切除术、肝切除术。当我们使用超声切除技术进行闭合性(根治性)手术干预时,减少了手术内和术后并发症,改善了肝包虫病患者的近期和长期疗效。
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引用次数: 2
Suprafascial application of Vancomycin powder in the operation of posterior instrumental fusion for the prevention of local infectious complications 万古霉素粉在后路器械融合术中筋膜上应用预防局部感染并发症
Q4 Medicine Pub Date : 2020-06-29 DOI: 10.24884/0042-4625-2020-179-2-33-39
Ivan A. Stepanov, V. A. Beloborodov, Maria A. Shameeva
INTRODUCTION. Surgical site infections (SSIs) are one of the most serious adverse events that develop in patients after performing an operation of instrumental spinal fusion. A search of literary sources in various databases showed the presence of isolated studies devoted to studying the effectiveness of suprafascial local application of Vancomycin powder after performing an operation of posterior instrumental spinal fusion in preventing the development of SSIs. At the same time, the results of these studies are ambiguous and in many ways contradictory.The OBJECTIVE of this study was to study the effectiveness of the suprafascial local application of Vancomycin powder after performing the operation of the posterior instrumental spinal fusion in preventing the development of SSIs, and also to identify the main adverse drug reactions in the local use of this antibacterial drug.METHODS AND MATERIALS. The study included medical records of 219 patients who underwent surgery for posterior instrumental spinal fusion on the cervical, thoracic, and lumbosacral spine for various pathological conditions. Medical records of patients are divided into two groups: group I (comparison group) – 113 patients who used the standard protocol of prophylaxis of SSIs and group II (main group) – 106 patients who used the standard protocol of prophylaxis of SSIs in combination with suprafascial local use of Vancomycin powder. The analysis of the frequency of occurrence of SSIs after the operation of the posterior instrumental spinal fusion in the studied groups of respondents and the prevalence of undesirable medicinal phenomena in the case of local suprafascial application of Vancomycin powder was performed.RESULTS. The prevalence of SSI after posterior instrumental spinal fusion in the control group of patients was 4.2 %. At the same time, in the main group of patients, where the standard protocol was used in combination with suprafascial local use of Vancomycin powder for the purpose of prophylaxis of SSIs, there were no cases of SSIs development. We have not revealed any adverse drug reactions when using Vancomycin powder in patients of the main group.CONCLUSION. The local use of Vancomycin powder in patients after posterior instrumental spinal fusion is an effective and safe method of preventing the development of SSIs.
介绍。手术部位感染(ssi)是器械脊柱融合术后发生的最严重的不良事件之一。通过对各种数据库文献资料的检索,我们发现有孤立的研究致力于研究后路器械脊柱融合术后筋膜上局部应用万古霉素粉末对预防ssi发生的有效性。与此同时,这些研究的结果是模糊的,在许多方面是相互矛盾的。本研究的目的是研究后路器械脊柱融合术后筋膜上局部应用万古霉素粉剂预防ssi发生的有效性,并明确该抗菌药物局部使用的主要药物不良反应。方法和材料。该研究包括219例因不同病理情况而接受后路颈椎、胸椎和腰骶椎融合术的患者的医疗记录。患者病历分为两组:I组(对照组)- 113例患者采用ssi预防标准方案;II组(主组)- 106例患者采用ssi预防标准方案联合筋膜上局部使用万古霉素粉。分析调查对象后路器械脊柱融合术后ssi的发生频率及局部筋膜上应用万古霉素散剂后不良药物现象的发生率。对照组患者后路器械脊柱融合术后SSI发生率为4.2%。同时,在主组患者中,采用标准方案联合筋膜上局部使用万古霉素粉预防ssi,无ssi发生。本组患者使用万古霉素粉剂未见不良反应。后路器械脊柱融合术后患者局部使用万古霉素粉是一种有效、安全的预防ssi发生的方法。
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引用次数: 0
Organ-preserving surgical treatment of giant uterine myoma in a pregnant woman 孕妇巨大子宫肌瘤的器官保留手术治疗
Q4 Medicine Pub Date : 2020-06-29 DOI: 10.24884/0042-4625-2020-179-2-59-62
I. Khatkov, V. Tsvirkun, Yu. N. Ponоmareva, E. A. Loginova
Uterine myoma is the most common benign disease in the women of the reproductive period. According to different authors, the rate of uterine myoma in pregnancy is estimated from 0.1 to 12.5 %. We present the case of successful laparotomy myomectomy at 14–15 weeks of gestational age.
子宫肌瘤是女性育龄期最常见的良性疾病。根据不同作者的说法,怀孕期间子宫肌瘤的发病率估计在0.1%到12.5%之间。我们提出的情况下,成功剖腹子宫肌瘤切除术在14-15周孕龄。
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引用次数: 0
Diagnostics of postnecrotic pancreatic cysts (review of literature) 坏死后胰腺囊肿的诊断(文献复习)
Q4 Medicine Pub Date : 2020-06-29 DOI: 10.24884/0042-4625-2020-179-2-68-72
Г. А. Носков, Д. В. Фокин, А. Казадаева, D. V. Cherdantsev, O. V. Pervova, I. Noskov, Dmitry V. Fokin, A. A. Kazadaeva, I. A. Kazadaeva
The problem of diagnosing postnecrotic cysts of the pancreas is considered in this article. The characteristics of laboratory (determination of the level of amylase, cytological research of punctate, determination of tumor markers) and radiation (ultrasound, endosonography, RCP, MSCT, etc.) methods of research of this pathology are presented, their specificity in the differential diagnosis of cystic formations, depressurization of the main pancreatic duct and formation of the cyst wall is considered. We concluded that the use of radiation methods of research significantly improves the diagnosis of pseudocyst of the pancreas and allows to choose a rational treatment tactics and an adequate surgical intervention.
诊断胰腺坏死后囊肿的问题是考虑在这篇文章。介绍了该病理的实验室(淀粉酶水平测定、点状细胞学研究、肿瘤标志物测定)和放射(超声、超声、RCP、MSCT等)研究方法的特点,并考虑了其在囊性形成、主胰管减压和囊壁形成的鉴别诊断中的特异性。我们的结论是,使用放射方法的研究显着提高了胰腺假性囊肿的诊断,并允许选择合理的治疗策略和适当的手术干预。
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引用次数: 0
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Vestnik khirurgii imeni I. I. Grekova
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