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Trapped neutrophil syndrome in a young Border Collie dog: A new clinical presentation 一只年轻边境牧羊犬的中性粒细胞潴留综合征:一种新的临床表现
IF 0.3 Q4 VETERINARY SCIENCES Pub Date : 2024-04-30 DOI: 10.1002/vrc2.884
Arthur Petitpre, Anaïs Lamoureux
An 11‐month‐old Border Collie dog presented with recurrent fever since the age of 3 months. Clinical examination revealed stunted growth, facial dysmorphism, fever, oral and third eyelid ulcerations and stiff gait with tarsal hyperlaxity. Clinicopathologic testing revealed neutropenia with normal neutrophil maturation in the bone marrow, ulcerative neutrophilic stomatitis and glossitis and a nonperforating duodenal ulcer. Genetic testing showed a mutation in the vacuolar protein sorting‐associated protein 13B gene, establishing a diagnosis of trapped neutrophil syndrome. Steroid therapy was not prescribed due to the presence of a duodenal ulcer. Two weeks later, antibiotics and omeprazole facilitated a mild clinical improvement with relapse; euthanasia was subsequently elected. This case highlights clinical signs not previously described in dogs but known in humans with Cohen syndrome, including buccal ulcerations or joint hyperlaxity. This is also the first description of this disease in France, where Border Collies are commonly bred.
一只 11 个月大的边境牧羊犬自 3 个月大开始反复发烧。临床检查发现该犬发育迟缓、面部畸形、发烧、口腔和第三眼睑溃疡、步态僵硬并伴有跗关节肿大。临床病理检测显示,中性粒细胞减少,但骨髓中性粒细胞成熟正常,患有溃疡性中性粒细胞口腔炎和舌炎以及非穿孔性十二指肠溃疡。基因检测显示,空泡蛋白分选相关蛋白13B基因发生了突变,从而确诊为中性粒细胞受困综合征。由于十二指肠溃疡的存在,医生没有采用类固醇治疗。两周后,抗生素和奥美拉唑使其临床症状得到轻微改善,但病情复发;随后选择了安乐死。本病例强调了以前未在狗身上描述过、但在患有科恩综合征的人身上已知的临床症状,包括口腔溃疡或关节过度松弛。这也是法国首次描述这种疾病,因为边境牧羊犬通常在法国饲养。
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引用次数: 0
Anticoagulant rodenticide intoxication in a dog with pericardial effusion and a heart base mass‐like effect 一只患有心包积液和心底肿块样效应的狗体内的抗凝血杀鼠剂中毒症
IF 0.3 Q4 VETERINARY SCIENCES Pub Date : 2024-04-30 DOI: 10.1002/vrc2.877
Sean McCrae, Stephanie Skinner, Adesola Odunayo, Jacob Wolf
A 4‐year‐old American Pitbull terrier presented for acute onset of a honking cough, vomiting and anorexia. Thoracic radiographs revealed tracheal narrowing consistent with a mass effect or tracheal collapse. The dog was hospitalised but acutely developed respiratory distress, syncope and pale mucous membranes. Moderate pleural effusion and a heart base mass were noted on echocardiographic examination as well as evidence of cardiac tamponade. Coagulation times were severely prolonged. After additional discussion with the owners, rodenticide exposure was considered possible. The owners elected humane euthanasia. A necropsy revealed gross evidence of intrathoracic haemorrhage and a heart base mass consistent with a haematoma. There was no evidence of neoplasia on histopathological evaluation of the tissues. A final diagnosis of rodenticide intoxication was made. This case report demonstrates the importance of considering anticoagulant rodenticide intoxication in patients with a history of pericardial effusion. It is also important to consider a haematoma as a differential diagnosis when a heart‐associated mass is visualised in patients with pericardial effusion.
一只 4 岁大的美国比特斗牛梗犬因急性咳嗽、呕吐和厌食而就诊。胸片显示气管狭窄,与肿块效应或气管塌陷一致。该犬被送往医院,但很快出现呼吸困难、晕厥和粘膜苍白。超声心动图检查发现了中度胸腔积液和心底肿块,以及心脏填塞的证据。凝血时间严重延长。在与主人进一步讨论后,考虑到可能是接触了杀鼠剂。主人选择了人道安乐死。尸体解剖发现了胸腔内出血的严重证据,以及与血肿一致的心底肿块。组织病理学评估未发现肿瘤迹象。最终诊断为杀鼠剂中毒。本病例报告表明,对于有心包积液病史的患者,考虑抗凝血杀鼠剂中毒非常重要。当心包积液患者发现心脏相关肿块时,考虑血肿作为鉴别诊断也很重要。
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引用次数: 0
Congenital aural atresia in a 4‐month‐old Dalmatian 一只 4 个月大的达尔马提亚犬先天性耳道闭锁
IF 0.3 Q4 VETERINARY SCIENCES Pub Date : 2024-04-30 DOI: 10.1002/vrc2.881
Maria Dalla Fontana, Carlo Anselmi, John Williams, Lara Dempsey
A 4‐month‐old female entire Dalmatian was presented for persistently excessive ceruminous discharge, suspected left aural malformation and decreased hearing. Otoscopic examination of the left ear showed a normal external meatus with an abnormal ending of the ear canal in a cul‐de‐sac. Computed tomography (CT) study of the head showed a diffusely tortuous and convoluted external ear canal with saccular distension and a stenotic area with the presence of a septum. Based on the clinical presentation and imaging findings, total ear canal ablation and lateral bulla osteotomy were performed. Macroscopically, the ear canal appeared to be sigmoid, as in the CT study. Notably, in the stenotic area, there was a membrane separating the vertical and horizontal ear canals. The histopathology of the external ear canal was consistent with that of hyperplastic otitis externa. No growth was observed on bacterial culture. The dog recovered uneventfully and no abnormalities were detected on re‐examination 2 weeks post‐surgery.
一只 4 个月大的雌性整只达尔马提亚犬因持续过多的耵聍分泌物、怀疑左耳畸形和听力下降而就诊。左耳耳镜检查显示外耳道正常,耳道末端异常,呈死胡同状。头部计算机断层扫描(CT)显示,外耳道呈弥漫性迂曲,囊状扩张,狭窄部位存在中隔。根据临床表现和影像学检查结果,对患者进行了全耳道消融术和侧鼓室截骨术。从宏观上看,耳道呈乙状,与 CT 检查结果一致。值得注意的是,在狭窄区域,垂直耳道和水平耳道之间有一层薄膜分隔。外耳道的组织病理学与增生性外耳道炎一致。细菌培养未发现生长。该犬恢复顺利,术后两周复查时未发现异常。
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引用次数: 0
Measurement of proviral load associated with the development of lymphocytosis in bovine leukaemia virus‐infected Holstein cattle at a dairy farm in Japan 测定日本一家奶牛场中受牛白血病病毒感染的荷斯坦牛发生淋巴细胞增多症时的病毒载量
IF 0.3 Q4 VETERINARY SCIENCES Pub Date : 2024-04-30 DOI: 10.1002/vrc2.883
Kenichiro Kobayashi
We monitored the bovine leukaemia virus (BLV) proviral load (PVL) in peripheral blood lymphocytes (PBLs) and the PBL counts in BLV‐infected cattle on a dairy farm in Japan to determine the changes in PVL with the progression of lymphocytosis. A total of 25 BLV‐infected Holstein cattle at a dairy farm were followed up from May 2015 (0 month) to April 2016 (11 months). PBL counts and PVL were measured three times in 25 cattle. Based on their PBL counts, five cattle with normal PBL (≤7500 cells/µL) at 0 month but high PBL (>7500 cells/µL) at 11 months were classified as the increased group. All cattle in the increased group showed increased PVL compared to asymptomatic aleukaemic carriers at 11 months. This study revealed increases in PVL with the progression of lymphocytosis, suggesting that cattle with progression of lymphocytosis should be segregated from BLV‐negative cattle as soon as possible.
我们监测了日本一家奶牛场受BLV感染的牛的外周血淋巴细胞(PBL)中的牛白血病病毒(BLV)前病毒载量(PVL)和PBL计数,以确定随着淋巴细胞增多,PVL的变化情况。从2015年5月(0个月)到2016年4月(11个月),对一家奶牛场的25头BLV感染的荷斯坦牛进行了随访。对 25 头牛的 PBL 计数和 PVL 进行了三次测量。根据PBL计数,5头牛在0个月时PBL正常(≤7500个细胞/μL),但在11个月时PBL较高(7500个细胞/μL),这5头牛被归为增高组。与 11 个月时无症状的白血病携带者相比,增高组的所有牛的 PVL 都有所增高。这项研究表明,随着淋巴细胞增多症的发展,PVL 也会增加,这表明淋巴细胞增多症发展的牛应尽快与 BLV 阴性牛隔离。
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引用次数: 0
Spermatic cord torsion associated with perineal hernia in a cryptorchid dog 一只隐睾狗的精索扭转伴会阴疝
IF 0.3 Q4 VETERINARY SCIENCES Pub Date : 2024-04-30 DOI: 10.1002/vrc2.882
Vassiliki Tsioli, Evgenia Flouraki, Theodora Zacharopoulou
An 8‐year‐old male German Shepherd dog with a history of dyschezia, tenesmus and perineal swelling for 1 month was referred. The dog was known to be unilaterally abdominal cryptorchid. The normally descended testis had been surgically removed a few years ago. On physical examination, a firm, non‐painful, irreducible mass was palpable in the left perineal region. Digital rectal examination revealed rectal deviation, and the pelvic diaphragm was absent on the left. The prostate gland was normal upon palpation. Abdominal radiography revealed that the urinary bladder was present in the caudal abdomen. Based on clinical, laboratory and imaging findings, a diagnosis of perineal hernia was made. Surgical exploration revealed the presence of left spermatic cord torsion in the perineal hernia. The testis was removed, and internal obturator muscle transposition was performed for herniorrhaphy. The dog had an uneventful recovery, and the results of re‐examinations 10 days, 6 months and 12 months later were normal.
患者是一只 8 岁的雄性德国牧羊犬,曾有一个月的排便困难、拉稀和会阴部肿胀病史。据了解,该犬单侧腹部隐睾。正常下降的睾丸几年前已被手术切除。体格检查时,在左侧会阴部可触及一个坚实、无痛、不可复位的肿块。数字直肠检查显示直肠偏斜,左侧骨盆膈肌缺失。前列腺触诊正常。腹部放射线检查显示膀胱位于尾腹。根据临床、实验室和影像学检查结果,诊断为会阴疝。手术探查发现,会阴疝中存在左侧精索扭转。切除了睾丸,并进行了内闭孔肌转位疝切除术。该犬恢复顺利,10 天、6 个月和 12 个月后的复查结果均正常。
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引用次数: 0
Asymptomatic testicular torsion in a descended cat testicle 下降猫睾丸中无症状的睾丸扭转
IF 0.3 Q4 VETERINARY SCIENCES Pub Date : 2024-04-30 DOI: 10.1002/vrc2.880
Kristian Joyce
An incidental testicular torsion was discovered during orchiectomy of an approximately 4‐month‐old intact male kitten. His spermatic cord was twisted numerous times, which caused necrosis and swelling of the right teste. Despite these changes, the patient had no signs of pain or clinical signs typical of testicular torsion that is seen in other species. The owner of the kitten reported that the kitten was eating normally and did not show any signs of pain. The physical examination of the kitten did not reveal any tenderness upon palpation of the enlarged testicle. This case illustrates that testicular torsion is possible even in the absence of pain or discomfort in cats.
在对一只约 4 个月大的完整雄猫进行睾丸切除术时,意外发现了睾丸扭转。它的精索多次扭转,导致右侧睾丸坏死和肿胀。尽管出现了这些变化,但患者并没有疼痛症状,也没有其他物种睾丸扭转的典型临床症状。小猫的主人称,小猫进食正常,没有任何疼痛迹象。对小猫进行体格检查时,触诊肿大的睾丸时未发现任何触痛。本病例说明,即使猫没有疼痛或不适,也有可能发生睾丸扭转。
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引用次数: 0
Recurrent spontaneous pneumothorax in four surgically treated Japanese Spitz dogs 四只接受过手术治疗的日本斯皮茨犬的复发性自发性气胸
IF 0.3 Q4 VETERINARY SCIENCES Pub Date : 2024-04-16 DOI: 10.1002/vrc2.868
Celine Siew Lin Toh, Jayson Tuan
Four Japanese Spitz dogs between 5 and 11 months old were presented for acute dyspnoea. Thoracic radiographs and CT identified bilateral pneumothorax and pulmonary cavitary lesions. The median lesion size was 30 mm (range 7‒50 mm). After initial stabilisation, one dog underwent median sternotomy, while three dogs underwent intercostal thoracotomy. Surgical exploration found grossly haemorrhagic pulmonary bullous lesions in all cases. Histopathology revealed blood-filled cavities with interstitial fibrosis and pneumocyte hyperplasia. Dyspnoea recurred in all dogs postoperatively, with recurrence of lesions confirmed either radiographically or via CT in three of four cases. The median time from surgery to recurrence of pneumothorax was 9 days (range 5‒15 days). The mortality rate was 100%, and the median postoperative survival time was 22 days (range 5‒558 days). This report aims to raise awareness of this group of dogs presenting with spontaneous pneumothorax at a young age and with high recurrence rates despite surgery, contrary to the literature.
四只 5 到 11 个月大的日本斯比茨犬因急性呼吸困难就诊。胸片和 CT 检查发现了双侧气胸和肺腔病变。中位病变大小为 30 毫米(范围为 7-50 毫米)。在初步稳定病情后,一只狗接受了胸骨正中切开术,三只狗接受了肋间胸廓切开术。手术探查发现,所有病例都有严重出血的肺大泡病变。组织病理学检查发现,充血的空腔伴有间质纤维化和肺细胞增生。所有病犬在术后都再次出现呼吸困难,四例病例中有三例通过影像学或 CT 证实病变复发。从手术到气胸复发的中位时间为 9 天(5-15 天不等)。死亡率为 100%,术后存活时间中位数为 22 天(5-558 天不等)。本报告旨在提高人们对这类幼年即出现自发性气胸且手术后复发率较高的犬只的认识,这与文献记载的情况相反。
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引用次数: 0
Combined ultrasound- and nerve stimulator-guided brachial plexus nerve block in a pig undergoing olecranon fracture repair 超声波和神经刺激器联合引导臂丛神经阻滞术在接受肩胛骨骨折修复术的猪身上的应用
IF 0.3 Q4 VETERINARY SCIENCES Pub Date : 2024-04-16 DOI: 10.1002/vrc2.870
Toshitsugu Ishihara, Erik Hofmeister, Jenna Bayne, Stuart Clark-Price
A male pot-bellied pig was presented for left thoracic limb lameness. A fracture of the olecranon apophysis with displacement was diagnosed, and fracture stabilisation was performed under general anaesthesia. After anaesthetic induction, an axillary brachial plexus nerve block (BPB) with bupivacaine was performed using a portable ultrasound device and a nerve locator. Heart rate and blood pressure were monitored for nociception and the need for analgesic intervention during the procedure. No analgesic intervention was deemed necessary, as the pig did not meet predefined nociceptive thresholds. The pig recovered from general anaesthesia uneventfully without clinical signs of pain or complications. The affected limb was knuckled and lacked conscious proprioception immediately after recovery. Sixteen hours after BPB, knuckling resolved, and normal conscious proprioception was observed. No obvious adverse effects from BPB were noted. The combination of ultrasound and nerve stimulator-guided BPB with bupivacaine was successful in a pig.
一头雄性腹盆猪因左胸肢跛行就诊。确诊为肩胛骨骨骺骨折并移位,在全身麻醉下进行了骨折稳定手术。麻醉诱导后,使用便携式超声波设备和神经定位器进行了布比卡因腋臂丛神经阻滞(BPB)。在手术过程中,对心率和血压进行监测,以了解痛觉和是否需要镇痛干预。由于猪没有达到预先确定的痛觉阈值,因此认为没有必要进行镇痛干预。猪从全身麻醉中顺利恢复,没有出现疼痛或并发症的临床症状。恢复后患肢呈指节状,缺乏本体感觉。BPB 16 小时后,肢体屈曲消失,本体感觉正常。BPB 没有明显的不良反应。超声波和神经刺激器引导的布比卡因联合 BPB 在猪身上取得了成功。
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引用次数: 0
Osseous choanal atresia in a canine patient 一名犬科患者的骨性咽喉闭锁
IF 0.3 Q4 VETERINARY SCIENCES Pub Date : 2024-04-15 DOI: 10.1002/vrc2.862
Foteini Chrysanthakopoulou, Panagiotis Bourdekas, Maria Lyraki, Ioannis Panopoulos
A 2-year-old, male, intact dog presented with a history of stertorous breathing since infancy, unresponsive to antibiotic therapy. On rostral rigid endoscopy, there were no remarkable findings. However, computed tomography revealed bilateral atresia of the nasal choanae, with focal hyperossification and severe narrowing, with accompanying hypoventilation of the nasopharynx. Retrograde flexible nasopharyngoscopy confirmed the severe partial choanal atresia. Surgical intervention was declined by the owner due to reasonably acceptable quality of life; therefore, only environmental modifications and symptomatic care have been implemented so far.
一只两岁大的雄性完整犬自婴儿期起就出现呼吸困难,对抗生素治疗无反应。喙硬质内窥镜检查没有发现明显异常。然而,计算机断层扫描却发现双侧鼻腔咽喉闭锁,并伴有局灶性过度肥厚和严重狭窄,同时鼻咽部通气不足。逆行柔性鼻咽内窥镜检查证实了它的鼻腔部分严重闭锁。由于它的生活质量尚可,主人拒绝了手术治疗;因此,到目前为止,只对它进行了环境改造和对症护理。
{"title":"Osseous choanal atresia in a canine patient","authors":"Foteini Chrysanthakopoulou, Panagiotis Bourdekas, Maria Lyraki, Ioannis Panopoulos","doi":"10.1002/vrc2.862","DOIUrl":"https://doi.org/10.1002/vrc2.862","url":null,"abstract":"A 2-year-old, male, intact dog presented with a history of stertorous breathing since infancy, unresponsive to antibiotic therapy. On rostral rigid endoscopy, there were no remarkable findings. However, computed tomography revealed bilateral atresia of the nasal choanae, with focal hyperossification and severe narrowing, with accompanying hypoventilation of the nasopharynx. Retrograde flexible nasopharyngoscopy confirmed the severe partial choanal atresia. Surgical intervention was declined by the owner due to reasonably acceptable quality of life; therefore, only environmental modifications and symptomatic care have been implemented so far.","PeriodicalId":23496,"journal":{"name":"Veterinary Record Case Reports","volume":"73 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140560758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sinus arrest during thoracic drain placement in a dog 狗在放置胸腔引流管时窦性停搏
IF 0.3 Q4 VETERINARY SCIENCES Pub Date : 2024-04-15 DOI: 10.1002/vrc2.869
Annie Mulligan, Daniel Nicholls
A 5‐year‐old female neutered Podenco Canario dog presented with a moderate pleural effusion and subsequently underwent placement of bilateral thoracic drains. Pre‐medication consisted of intravenous medetomidine (2 µg/kg) and methadone (0.2 mg/kg), followed by induction with propofol (2.1 mg/kg, via intravenous administration). Anaesthesia was maintained with isoflurane in 100% oxygen. The modified Seldinger technique was used to place bilateral small‐bore, wire‐guided thoracic drains. During placement of the first chest drain, the dog developed sinus arrest. It is suspected that there was direct vagal nerve stimulation by the guide wire during placement, leading to severe bradycardia and subsequent sinus arrest that was responsive to atropine. It is important to note that the definitive cause of the transient cardiac arrest could not be ascertained. It is possible that this is a rare complication of thoracic drain placement, warranting further research in this area.
一只 5 岁的雌性阉割波登科-卡纳里奥犬出现中度胸腔积液,随后接受了双侧胸腔引流术。术前用药包括静脉注射美托咪定(2 微克/千克)和美沙酮(0.2 毫克/千克),然后使用异丙酚(2.1 毫克/千克,通过静脉注射)进行诱导。使用异氟醚和 100% 氧气维持麻醉。采用改良的 Seldinger 技术放置双侧小孔导丝胸腔引流管。在放置第一根胸腔引流管时,该犬出现了窦性停搏。怀疑在放置引流管时,导丝直接刺激了迷走神经,导致严重心动过缓,随后窦性停搏,对阿托品有反应。值得注意的是,一过性心跳骤停的确切原因无法确定。这可能是胸腔引流管置入术中的一种罕见并发症,值得在这一领域开展进一步研究。
{"title":"Sinus arrest during thoracic drain placement in a dog","authors":"Annie Mulligan, Daniel Nicholls","doi":"10.1002/vrc2.869","DOIUrl":"https://doi.org/10.1002/vrc2.869","url":null,"abstract":"A 5‐year‐old female neutered Podenco Canario dog presented with a moderate pleural effusion and subsequently underwent placement of bilateral thoracic drains. Pre‐medication consisted of intravenous medetomidine (2 µg/kg) and methadone (0.2 mg/kg), followed by induction with propofol (2.1 mg/kg, via intravenous administration). Anaesthesia was maintained with isoflurane in 100% oxygen. The modified Seldinger technique was used to place bilateral small‐bore, wire‐guided thoracic drains. During placement of the first chest drain, the dog developed sinus arrest. It is suspected that there was direct vagal nerve stimulation by the guide wire during placement, leading to severe bradycardia and subsequent sinus arrest that was responsive to atropine. It is important to note that the definitive cause of the transient cardiac arrest could not be ascertained. It is possible that this is a rare complication of thoracic drain placement, warranting further research in this area.","PeriodicalId":23496,"journal":{"name":"Veterinary Record Case Reports","volume":"39 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140560756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Veterinary Record Case Reports
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