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Technical note: Improving orbital atherectomy efficacy for calcified nodules using a curved guide catheter. 技术说明:使用弯曲导尿管提高眼眶动脉粥样硬化切除术治疗钙化结节的疗效。
IF 0.9 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-12-01 Epub Date: 2024-12-11 DOI: 10.1177/17085381241308110
Munehiro Iiya, Isshi Kobayashi, Yuko Onishi

ObjectivesEndovascular therapy (EVT) for calcified nodules in patients with peripheral artery disease (PAD) remains challenging in achieving favorable outcomes. This study aims to investigate the effectiveness of orbital atherectomy (OA) for calcified nodules using an IM catheter to precisely control the device and achieve optimal engagement with the target lesion.MethodsWe performed EVT for a calcified nodule in the right common femoral artery using an OA. Due to the large vessel size, controlling the OA to effectively engage the lesion was challenging. To overcome this, we utilized an IM catheter to guide the OA toward the target lesion.ResultsThe use of the IM catheter successfully directed the OA to the calcified lesion, resulting in significant lumen enlargement. The procedure was completed without any complications, and the OA achieved effective debulking of the calcified nodule.ConclusionsThe combination of OA and IM catheter facilitated effective contact with the target lesion, improving the performance of the debulking device. This approach may enhance the management of calcified lesions in large-diameter arteries during EVT, potentially leading to better clinical outcomes.

目的:外周动脉疾病(PAD)患者钙化结节的血管内治疗(EVT)在获得良好结果方面仍然具有挑战性。本研究旨在探讨使用IM导管进行眼眶动脉粥样硬化切除术(OA)治疗钙化结节的有效性,以精确控制设备并实现与目标病变的最佳接触。方法:我们使用OA对右股总动脉钙化结节进行EVT。由于血管尺寸较大,控制OA以有效接合病变具有挑战性。为了克服这个问题,我们使用了IM导管将OA引导到目标病变。结果:使用IM导管成功地将OA引导到钙化病变处,导致明显的管腔扩大。手术完成后无任何并发症,OA实现了钙化结节的有效减积。结论:OA与IM导管联合使用有利于与靶病变有效接触,提高了减体积装置的性能。这种方法可以加强EVT期间大直径动脉钙化病变的管理,可能导致更好的临床结果。
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引用次数: 0
Common carotid artery reconstruction with superficial femoral artery: Surgical steps to use fresh in vivo arterial homograft. 股浅动脉重建颈总动脉:活体新鲜同种动脉移植的外科步骤。
IF 0.9 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-12-01 Epub Date: 2024-11-29 DOI: 10.1177/17085381241305189
Francesco Sposato, Ottavia Borghese, Yamume Tshomba

ObjectivesThe use of homograft for vascular reconstruction is a common practice in infective setting or to prevent aneurysmal dilation over the time. The use of fresh arterial homograft is conversely rarely reported.MethodsWe report a case about the use of fresh arterial homograft as a substitute of carotid intra-stent stenosis.ResultsWe describe the several steps of the procedure of a carotid stent graft explant and reconstruction with the interposition of the superficial femoral artery in a 29-year-old patient presenting with a carotid intra-stent stenosis. One-month postoperatively, the DUS showed the patency of the bypass graft.ConclusionsFresh in vivo superficial femoral artery for common carotid artery reconstruction may be considered in young patient as it provides excellent size-match, resistance to infection and low risk of aneurysmal degeneration.

目的:同种移植物用于血管重建是一种常见的做法,在感染或防止动脉瘤扩张随着时间的推移。相反,新鲜动脉同种移植物的使用很少报道。方法:我们报告一例用新鲜同种动脉移植代替颈动脉支架内狭窄的病例。结果:我们描述了一个29岁的颈动脉支架内狭窄患者颈动脉支架内移植和股浅动脉介入重建的几个步骤。术后1个月,DUS显示搭桥通畅。结论:年轻患者可考虑采用新鲜的体外股浅动脉进行颈总动脉重建,因为它具有良好的尺寸匹配性、抗感染能力和较低的动脉瘤变性风险。
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引用次数: 0
Comparison of a compression for seven days or overnight after endovenous radiofrequency ablation of superficial vein: A randomized controlled trial. 静脉内射频消融浅表静脉后7天或一夜压迫的比较:一项随机对照试验。
IF 0.9 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-12-01 Epub Date: 2024-12-10 DOI: 10.1177/17085381241302147
Nawaphan Taengsakul, Mullika Buttakosa, Marisa Kijrattana

ObjectiveTo compare the efficacy of compression stockings worn for 7 days or overnight after EVRFA.MethodsA single-centre, prospective, non-inferiority randomised controlled trial. The study included patients with clinical class C2-C4 chronic venous disease who underwent endovenous radiofrequency ablation (EVRFA) at Chulabhorn Hospital between October 2021 and October 2023. Sixty patients were assigned to wear the overnight compression group (n = 30) or for the 7-day compression group (n = 30). The primary outcome was targeted vein obliteration at 12 weeks. The secondary outcome measures were the revised Venous Clinical Severity Score (r-VCSS), Aberdeen Varicose Veins Severity Score (AVSS), pain score, complications and patient satisfaction.ResultsAt 12 weeks, both groups had a 100% target vein occlusion rate. There was no statistically significant difference in the r-VCSS, AVSS, patient satisfaction score, complications or pain score at day 1, day 14 and 12-16 weeks after the procedure. Overnight compression improved r-VCSS significantly.ConclusionOvernight compression was non-inferior to compression for 7 days after EVRFA.

目的:比较EVRFA术后7天和夜间穿压缩袜的效果。方法:单中心、前瞻性、非劣效性随机对照试验。该研究纳入了临床级别为C2-C4的慢性静脉疾病患者,这些患者于2021年10月至2023年10月在朱拉蓬医院接受了静脉内射频消融(EVRFA)。60例患者被分配到夜间压迫组(n = 30)或7天压迫组(n = 30)。12周时的主要结果是靶向静脉闭塞。次要结局指标为修订后的静脉临床严重程度评分(r-VCSS)、阿伯丁静脉曲张严重程度评分(AVSS)、疼痛评分、并发症和患者满意度。结果:12周时,两组静脉目标闭塞率均为100%。术后第1天、第14天和第12-16周的r-VCSS、AVSS、患者满意度评分、并发症或疼痛评分差异无统计学意义。夜间压缩显著改善了r-VCSS。结论:EVRFA术后7天的夜间压迫效果不逊于夜间压迫。
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引用次数: 0
Intercostal bypass graft pseudoaneurysm repaired with percutaneous glue embolization utilizing CT needle guidance: A case report. CT针引导下经皮胶栓塞修复肋间搭桥术假性动脉瘤1例。
IF 0.9 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-12-01 Epub Date: 2024-12-05 DOI: 10.1177/17085381241305177
James Moroney, Andrew Plumb, Matthew Scheidt, Michael Malinowski

ObjectivesPseudoaneurysm formation in connective tissue patients postoperatively can be a challenging and life-threatening problem to treat. Repair of an aorta to intercostal bypass graft pseudoaneurysm post open thoracoabdominal aortic aneurysm repair by percutaneous glue embolization utilizing Dyna CT Needle Guidance technology is a safe, minimally invasive method with low morbidity and short post-procedural recovery.MethodsA 30-year-old male with suspected connective tissue disorder who developed a Type B aortic dissection complicated by limb threatening right lower extremity ischemia treated with left-to-right fem-fem bypass and RLE fasciotomies. His thoracic aortic dissection subsequently was repaired urgently for persistent chest pain and rapid aortic expansion by open thoracoabdominal aortic aneurysm repair with aorta to intercostal bypass graft. Seven weeks postop patient presented with hemoptysis and was noted to have an enlarging T9 intercostal pseudoaneurysm requiring repair.Results and conclusionsPost discharge follow-up thoracic CTA performed showed complete resolution of the T9 intercostal pseudoaneurysm. Therefore, percutaneous NBCA glue embolization with iGuide technology is a viable alternative to open thoracic pseudoaneurysm repair and offers distinct advantages over other imaging modalities for localization.

目的:结缔组织患者术后假性动脉瘤形成是一个具有挑战性和危及生命的问题。应用Dyna CT针导向技术经皮胶栓塞修复开放性胸腹主动脉瘤是一种安全、微创、发病率低、术后恢复时间短的方法。方法:1例30岁男性,疑似结缔组织病变,B型主动脉夹层合并肢体威胁性右下肢缺血,行左至右femm -fem搭桥和RLE筋膜切开术治疗。由于持续的胸痛和快速的主动脉扩张,他的胸主动脉夹层随后被紧急修复,通过开胸腹主动脉瘤修复和主动脉肋间旁路移植术。术后7周,患者出现咯血,T9肋间假性动脉瘤增大,需要修复。结果和结论:出院后随访胸部CTA显示T9肋间假性动脉瘤完全消退。因此,经皮NBCA胶栓塞与guidide技术是开放性胸腔假性动脉瘤修复的可行选择,与其他成像方式相比具有明显的定位优势。
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引用次数: 0
Empowering junior doctors: A study on the feasibility and efficacy of ultrasound AAA screening in rural Australia. 增强初级医生的能力:澳大利亚农村地区 AAA 超声筛查的可行性和有效性研究。
IF 0.9 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-12-01 Epub Date: 2024-11-17 DOI: 10.1177/17085381241301529
Mei Ping Melody Koo, Hansraj Riteesh Bookun

PurposesAbdominal Aortic Aneurysm (AAA) screening via ultrasound in Caucasian males aged 65 and older has proven cost-effective in metropolitan areas. Evidence suggests that with adequate training, individuals without prior sonography experience can achieve accurate aortic measurements. This study evaluates the capability of junior doctors, after brief training, to conduct reliable AAA ultrasound screenings in a rural hospital setting, addressing the gap in speciality surgical services.MethodsThree junior doctors participated in a 2-hour practical ultrasound training, subsequently performing scans on both inpatients and community volunteers at a regional hospital. The analysis focused on measurement discrepancies within a 5 mm clinically acceptable difference, scanning efficiency, and aneurysm detection accuracy.ResultsA total of 71 participants were included. Among the screenings, 81.7% fell within the clinically acceptable discrepancy range, with 72.7% accuracy in inpatient scans and 95.5% in volunteer scans. Measurement reproducibility improved significantly with the standardisation of ultrasound techniques, and there was excellent agreement among operators in detecting aneurysms. Notably, scanning efficiency improved from the inpatient group to the volunteer group with statistical significance.ConclusionsJunior doctors demonstrated the ability to efficiently and reproducibly measure the infrarenal aortic diameter at a level comparable to experienced sonographers after only 2 hours of training. A single day of supervised practice is recommended to ensure standardised ultrasound technique. This approach offers a practical, cost-effective supplement to specialist radiology services in rural areas, enhancing access to critical screening procedures without proposing the replacement of professional sonographers.

目的:在大都市地区,通过超声波对 65 岁及以上的白种男性进行腹主动脉瘤(AAA)筛查已被证明具有成本效益。有证据表明,经过适当的培训,没有超声波检查经验的人也能进行准确的主动脉测量。本研究评估了初级医生经过短期培训后在农村医院进行可靠的 AAA 超声波筛查的能力,以弥补专科外科服务的不足:方法:三名初级医生参加了 2 小时的实用超声波培训,随后在一家地区医院对住院病人和社区志愿者进行了扫描。分析的重点是临床可接受的 5 毫米范围内的测量误差、扫描效率和动脉瘤检测准确性:结果:共纳入 71 名参与者。在筛查中,81.7%的差异在临床可接受范围内,住院患者扫描的准确率为72.7%,志愿者扫描的准确率为95.5%。随着超声技术的标准化,测量的可重复性明显提高,操作人员在检测动脉瘤方面的一致性极佳。值得注意的是,从住院病人组到志愿者组,扫描效率都有显著提高:结论:初级医生只需接受两小时的培训,就能高效、可重复地测量肾下主动脉直径,其水平可与经验丰富的超声技师媲美。建议进行为期一天的指导练习,以确保标准化的超声技术。这种方法为农村地区的专科放射服务提供了一种实用、经济高效的补充,在不建议取代专业超声技师的情况下提高了关键筛查程序的可及性。
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引用次数: 0
Endovascular abdominal aortic aneurysm repair (EVAR) outcomes of unibody and single/double docking limb endografts in Medicare beneficiaries between 2012 and 2018. 2012 年至 2018 年期间,医疗保险受益人使用单体和单/双对接肢内膜移植物进行血管内腹主动脉瘤修补术(EVAR)的疗效。
IF 0.9 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-12-01 Epub Date: 2024-11-13 DOI: 10.1177/17085381241300131
Mark F Conrad, Ami Sood, Alex O'Brien, Sapna Prasad, Erik Zendejas, Matt Thompson

ObjectiveThe evaluation of perioperative and long term outcomes for endovascular aneurysm repair (EVAR) of abdominal aortic aneurysms (AAA) using anatomic (unibody) and proximal neck fixated (docking limbs) endografts across consecutive time cohorts.DesignThis study compares the outcomes of EVAR in Medicare patients stratified by mode of fixation.MethodsAll patients who underwent EVAR between 2012 and 2018 were identified in the Medicare database. Anatomic fixation (AF) and proximal fixation (PF) grafts were differentiated using Current Procedural Terminology (CPT) codes. The AF population was divided into three-time cohorts based on iterative changes in graft design: Cohort 1: (01/01/2012-20/07/2014); Cohort 2: (21/07/2014-09/05/2016); and Cohort 3: (10/05/2016-31/12/2017). The PF cohort was similarly divided into these three periods. Outcomes were evaluated through 31/12/2020 and included all-cause mortality, aortic rupture, and aortic-related reintervention.Results32,031 patients underwent EVAR during the study period; 4729 were AF and 27,302 were PF. There were more women (p < .001) and patients with peripheral vascular disease (PVD) (p < .001) in the AF group. There were no group differences in perioperative outcomes. In Cohort 1, there was a higher rate of reintervention (11.9% vs 7.6%; p < .001) and aortic rupture (5.3% vs 4.0%; p = .019) in the AF group compared to the PF group. In Cohort 2, reintervention, aortic rupture, and reintervention rates were similar between the two groups (p = NS). In Cohort 3, the reintervention and aortic rupture rates were similar between the two groups (p = NS).ConclusionThe higher rates of aortic rupture and reintervention seen in the AF group in Cohort 1 when compared with the PF group did not persist in Cohorts 2 and 3. This suggests that improvements in graft design may have led to durability which is similar to that of PF grafts. However, late aneurysm related complications are inherent risks after EVAR and long-term surveillance remains necessary.

目的:评估使用解剖型(单体)和近端颈部固定型(对接肢)内移植物进行腹主动脉瘤(AAA)血管内动脉瘤修补术(EVAR)的围术期和长期疗效:本研究比较了按固定方式分层的医疗保险患者的 EVAR 结果:所有在 2012 年至 2018 年期间接受 EVAR 的患者均在医疗保险数据库中进行了识别。使用当前程序术语(CPT)代码对解剖固定(AF)和近端固定(PF)移植物进行区分。根据移植物设计的迭代变化,将 AF 群体分为三个队列:队列 1:(01/01/2012-20/07/2014);队列 2:(21/07/2014-09/05/2016);队列 3:(10/05/2016-31/12/2017)。PF 组群同样分为这三个时期。结果评估至2020年12月31日,包括全因死亡率、主动脉破裂和主动脉相关再介入:研究期间有 32031 名患者接受了 EVAR,其中 4729 人为房颤患者,27302 人为 PF 患者。房颤组中女性(p < .001)和外周血管疾病(PVD)患者(p < .001)更多。围手术期结果没有组间差异。在队列 1 中,房颤组的再介入率(11.9% vs 7.6%; p < .001)和主动脉破裂率(5.3% vs 4.0%; p = .019)高于 PF 组。在队列 2 中,两组的再介入率、主动脉破裂率和再介入率相似(p = NS)。在队列 3 中,两组的再介入率和主动脉破裂率相似(P = NS):结论:与主动脉瓣置换术组相比,主动脉瓣置换术组的主动脉破裂率和再介入率较高,但这一现象在第二组和第三组中并未持续。这表明移植物设计的改进可能导致其耐用性与 PF 移植物相似。然而,EVAR术后动脉瘤相关的晚期并发症是固有的风险,因此仍有必要进行长期监测。
{"title":"Endovascular abdominal aortic aneurysm repair (EVAR) outcomes of unibody and single/double docking limb endografts in Medicare beneficiaries between 2012 and 2018.","authors":"Mark F Conrad, Ami Sood, Alex O'Brien, Sapna Prasad, Erik Zendejas, Matt Thompson","doi":"10.1177/17085381241300131","DOIUrl":"10.1177/17085381241300131","url":null,"abstract":"<p><p>ObjectiveThe evaluation of perioperative and long term outcomes for endovascular aneurysm repair (EVAR) of abdominal aortic aneurysms (AAA) using anatomic (unibody) and proximal neck fixated (docking limbs) endografts across consecutive time cohorts.DesignThis study compares the outcomes of EVAR in Medicare patients stratified by mode of fixation.MethodsAll patients who underwent EVAR between 2012 and 2018 were identified in the Medicare database. Anatomic fixation (AF) and proximal fixation (PF) grafts were differentiated using Current Procedural Terminology (CPT) codes. The AF population was divided into three-time cohorts based on iterative changes in graft design: Cohort 1: (01/01/2012-20/07/2014); Cohort 2: (21/07/2014-09/05/2016); and Cohort 3: (10/05/2016-31/12/2017). The PF cohort was similarly divided into these three periods. Outcomes were evaluated through 31/12/2020 and included all-cause mortality, aortic rupture, and aortic-related reintervention.Results32,031 patients underwent EVAR during the study period; 4729 were AF and 27,302 were PF. There were more women (<i>p</i> < .001) and patients with peripheral vascular disease (PVD) (<i>p</i> < .001) in the AF group. There were no group differences in perioperative outcomes. In Cohort 1, there was a higher rate of reintervention (11.9% vs 7.6%; <i>p</i> < .001) and aortic rupture (5.3% vs 4.0%; <i>p</i> = .019) in the AF group compared to the PF group. In Cohort 2, reintervention, aortic rupture, and reintervention rates were similar between the two groups (p = NS). In Cohort 3, the reintervention and aortic rupture rates were similar between the two groups (p = NS).ConclusionThe higher rates of aortic rupture and reintervention seen in the AF group in Cohort 1 when compared with the PF group did not persist in Cohorts 2 and 3. This suggests that improvements in graft design may have led to durability which is similar to that of PF grafts. However, late aneurysm related complications are inherent risks after EVAR and long-term surveillance remains necessary.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"1266-1273"},"PeriodicalIF":0.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142629070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Addressing complications of large bore access in endovascular and cardiovascular procedures: An illustration of treatment options. 处理血管内和心血管手术中大口径通路的并发症:治疗方案的说明。
IF 0.9 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-12-01 Epub Date: 2024-12-12 DOI: 10.1177/17085381241307762
Dipankar Mukherjee, Bibhas Amatya, Melissa Lirag, Nelson Bernardo

BackgroundEndovascular procedures requiring large bore access, such as Transcatheter Aortic Valve Replacement (TAVR), Thoracic Endovascular Aortic Repair (TEVAR), and Endovascular Aneurysm Repair (EVAR), have become increasingly common. Despite advancements, complications from these procedures pose clinical challenges, especially in elderly and frail patients. The clinical objective of this paper is to demonstrate the complexities and innovative management strategies for complications that arise from large bore access.Case ReportThis report presents two cases illustrating percutaneous management of complications arising from large bore access during endovascular interventions. The first case involves a 74-year-old Asian female with a history of type A aortic dissection, who underwent TEVAR using a Gore TBE endograft. Post-procedure, the patient developed hemorrhagic shock due to disruption of the right external iliac artery. Interventions included upsizing the left femoral artery sheath, CODA balloon inflation in the distal aorta, and deployment of multiple VBX stents. The second case features a 24-year-old Caucasian female with a large pseudoaneurysm at the cannulation site in the aortic arch following a heart transplant. Successful TEVAR was performed to exclude the pseudoaneurysm. Closure of the right femoral artery access using 6 French ProGlide sutures was complicated, requiring balloon angioplasty to create an opening in the common femoral artery.ConclusionsThese cases highlight the challenges and innovative strategies in managing complications associated with large bore access during endovascular procedures. Insights gained from these experiences contribute to the armamentarium of interventionists, offering valuable guidance in addressing similar scenarios.

背景:需要大口径通道的血管内手术,如经导管主动脉瓣置换术(TAVR)、胸血管内主动脉瓣修复术(TEVAR)和血管内动脉瘤修复术(EVAR),已经变得越来越普遍。尽管取得了进步,但这些手术的并发症给临床带来了挑战,特别是在老年人和体弱患者中。本文的临床目的是展示复杂性和创新的管理策略,从大孔通道引起的并发症。病例报告:本报告介绍了两个病例,说明了在血管内介入术中因大孔通路引起的并发症的经皮处理。第一个病例是一名74岁的亚洲女性,有a型主动脉夹层病史,她使用Gore TBE内移植物接受了TEVAR。手术后,由于右髂外动脉破裂,患者出现失血性休克。干预措施包括扩大左股动脉鞘,远端主动脉CODA球囊膨胀,以及部署多个VBX支架。第二个病例是一位24岁的白人女性,在心脏移植后主动脉弓插管处有一个巨大的假性动脉瘤。TEVAR成功排除了假性动脉瘤。使用6个French ProGlide缝合线关闭右股动脉通道是复杂的,需要球囊血管成形术在股总动脉上开一个口。结论:这些病例强调了在血管内手术中处理大孔通路相关并发症的挑战和创新策略。从这些经验中获得的见解有助于为干预主义者提供装备,为解决类似情况提供宝贵的指导。
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引用次数: 0
Outcomes of drug-coated balloon angioplasty in patients with dyslipidemia in the BIOLUX P-III registry: A subgroup analysis. BIOLUX P-III 登记中血脂异常患者接受药物涂层球囊血管成形术的疗效:亚组分析。
IF 0.9 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-12-01 Epub Date: 2024-08-19 DOI: 10.1177/17085381241275795
James Evan Dodd, Joseph Hanna, Marianne Brodmann, Jonathan Golledge, Thomas Zeller, Matej Moscovic, Johannes Dahm, Nicola Troisi, Gunnar Tepe, Jacqueline Wong, Natalie C Ward, Bibombe Patrice Mwipatayi

ObjectivesThe aim of this study was to assess the mid-term outcomes of the use of drug-coated balloons (DCBs) to treat infrainguinal peripheral arterial disease (PAD) in patients with dyslipidemia.MethodsBIOLUX P-III is a prospective, international, multicenter, all-comers registry-based study that was conducted at 44 sites with follow-ups at 6, 12 and 24 months. The present study is a subgroup analysis comparing the outcomes associated with endovascular revascularization with those associated with Passeo-18 lux DCBs in patients with and without dyslipidemia. The proportions of patients free from major adverse events (defined as device- or procedure-related mortality within 30 days, clinically driven target lesion revascularization (CD-TLR) and major target limb amputation), target vessel revascularization, and patient-reported outcomes within 24 months postintervention were compared between the two groups.ResultsA total of 876 patients with symptomatic PAD who underwent peripheral revascularization with DCBs and had information on their dyslipidemia status were included; 588 of those patients had dyslipidemia. There was no difference in the proportion of patients free from MAEs between the groups. The percentages of patients who were 6, 12 and 24 months free from CD-TLR were significantly lower in the dyslipidemia group than in the nondyslipidemia group (86.3% vs 91.9% at 2 years, p = .0183). Similarly, the percentage of patients free from target vessel revascularization was lower in the dyslipidemia group at all timepoints (83.3% vs 89.3% at 2 years, p = .0203). There was no difference in mortality or major or minor limb amputation rates. Other secondary outcomes were similar between the groups.ConclusionsCompared to those without dyslipidemia, patients with symptomatic PAD and dyslipidemia who underwent revascularization with a Passeo-18 lux DCB had greater rates of CD-TLR and TVR. However, having dyslipidemia did not increase the risk of mortality or limb amputation.Clinical Trial RegistrationNCT02276313.

研究目的本研究旨在评估使用药物涂层球囊(DCB)治疗血脂异常患者腹股沟下外周动脉疾病(PAD)的中期疗效:BIOLUX P-III 是一项以登记为基础的前瞻性国际多中心研究,在 44 个地点进行,随访时间为 6、12 和 24 个月。本研究是一项亚组分析,比较了血脂异常和无血脂异常患者进行血管内再通术与使用Passeo-18勒克斯DCB的相关结果。研究比较了两组患者在干预后24个月内无重大不良事件(定义为30天内与设备或手术相关的死亡率、临床驱动的靶病变血运重建(CD-TLR)和主要靶肢截肢)、靶血管血运重建和患者报告结果的比例:共纳入了876名接受DCB外周血管重建术的无症状PAD患者,其中588名患者患有血脂异常。两组患者无 MAEs 的比例没有差异。血脂异常组患者在 6、12 和 24 个月内无 CD-TLR 的比例明显低于非血脂异常组(2 年时分别为 86.3% 和 91.9%,P = 0.0183)。同样,在所有时间点上,血脂异常组患者未发生靶血管再通的比例均低于非血脂异常组(2 年时分别为 83.3% 和 89.3%,P = 0.0203)。死亡率、主要或次要肢体截肢率没有差异。两组患者的其他次要结果相似:结论:与没有血脂异常的患者相比,有症状的PAD和血脂异常患者接受Passeo-18勒克斯DCB血管再通术后,CD-TLR和TVR的发生率更高。然而,血脂异常并不会增加死亡率或肢体截肢的风险:临床试验注册:NCT02276313。
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引用次数: 0
Extracranial internal carotid artery aneurysm: Surgical approach to a rare entity. 颅外颈内动脉瘤:罕见病例的手术方法。
IF 0.9 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-12-01 Epub Date: 2024-10-13 DOI: 10.1177/17085381241290634
Didem Melis Oztas, Seckin Cobanoglu, Asli Cakir, Okan Kuguoglu, Emre Oteyaka, Murat Ugurlucan

BackgroundExtracranial internal carotid artery aneurysms are rare entities that arise within the carotid triangle. Although rare, they are clinically significant due to the risk of neurologic thromboembolic events, compression of cranial nerves and vasculature, rupture, and ischemia.ObjectiveSurgery is the gold-standard treatment for symptomatic patients of all ages with extracranial internal carotid artery aneurysm.MethodA 26-year-old female patient was admitted to our institution with complaints of left auricular pain, hoarseness, and uncontrollable hypertension. She had a pulsatile mass located at the left cervical region. After diagnosing the extracranial internal carotid artery aneurysm, it was decided that surgery was necessary to relieve the patient's discomfort and prevent possible complications from the aneurysm in the left carotid artery.ResultIn the operation, the aneurysmatic segment was resected and sent for histopathological evaluation. Saphenous vein graft was interposed as end to end anastomosis to the proximal and distal healthy segments of the internal carotid artery.ConclusionThis case report highlights the surgical management of a 26-year-old female patient who presented to our institution with complaints of left auricular pain, hoarseness, uncontrolled hypertension, and a pulsatile mass localized at the left cervical region and diagnosed extracranial internal carotid artery aneurysm.

背景:颅外颈内动脉瘤是发生在颈动脉三角内的罕见实体。虽然罕见,但由于存在神经系统血栓栓塞事件、压迫颅神经和血管、破裂和缺血的风险,因此具有重要的临床意义:手术是治疗有症状的各年龄段颅外颈内动脉瘤患者的金标准:一名 26 岁的女性患者因主诉左耳疼痛、声音嘶哑和无法控制的高血压而入住我院。她的左颈部有一个搏动性肿块。在诊断出颅内颈内动脉瘤后,医生决定必须进行手术治疗,以缓解患者的不适症状,并防止左侧颈内动脉瘤可能引发的并发症:手术切除了动脉瘤部分,并送去进行组织病理学评估。结果:手术中,动脉瘤部分被切除,并送去进行组织病理学评估,无隐静脉移植作为端对端吻合器与颈内动脉的近端和远端健康部分相连:本病例报告重点介绍了一名 26 岁女性患者的手术治疗情况,该患者因主诉左耳疼痛、声音嘶哑、高血压未得到控制、左颈部局部有搏动性肿块而到我院就诊,诊断为颅外颈内动脉瘤。
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引用次数: 0
Comparing anticoagulant therapy alone, anticoagulant therapy in combination with catheter-directed thrombolysis, and anticoagulant therapy in combination with pharmacomechanical catheter-directed thrombolysis in the patients with optional inferior vena cava filter-related thrombosis: A single-center retrospective study. 在可选的下腔静脉滤器相关血栓形成患者中,比较单纯抗凝疗法、抗凝疗法与导管引导溶栓相结合,以及抗凝疗法与药物机械导管引导溶栓相结合:单中心回顾性研究
IF 0.9 4区 医学 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-12-01 Epub Date: 2024-10-12 DOI: 10.1177/17085381241289825
Zhaoyang Li, Zhicheng Duan, Huitang Yang, Meng Li, Yandong Cai, Zhan Jiang, Guoju Fan, Kaiqiang Wang, Bo Chen, Hongwei Zhang, Yankui Li
<p><p>ObjectiveTo analyze the treatment methods and efficacy of inferior vena cava filter thrombosis (IVCFT).Materials and methodsIn this retrospective study, the clinical data for 47 patients with IVCFT who underwent sequential treatment at the Department of Vascular Surgery, Tianjin Medical University Second Hospital, from January 2020 to January 2023 were analyzed. Patients were divided into three groups according to the treatment method: anticoagulant therapy (AC group), anticoagulation plus catheter-directed thrombolysis (CDT group), and anticoagulation plus AngioJet thrombectomy plus catheter-directed thrombolysis (PCDT group). The evaluation criteria for efficacy mainly included preoperative and postoperative clinical symptoms (Villalta score), thrombus diameter, thrombus clearance rate, filter retrieval rate, filter retention time, and urokinase dosage.ResultsThis study included 47 patients, of whom 31 were males (65.9%) and 16 females (34.1%), with a mean age of 72.05 ± 8.32 years. An Aegisy filter was used in seven patients, whereas an Illicium filter was used in forty patients. There were a total of nineteen patients in the anticoagulation-only group, with complete dissolution of the intraluminal thrombus in five patients, a residual thrombus with a maximum diameter ≤1 cm in three patients, and a residual thrombus with a maximum diameter >1 cm in eleven patients. The Villalta score was 7.16 ± 0.6 before treatment and decreased to 3.79 ± 0.59 after treatment. The thrombus diameter decreased from an average of 1.46 ± 0.2 cm before treatment to an average of 0.85 ± 0.14 cm after treatment. The retrieval rate for the filters was 42.11% (8/19), with an average dwell time of 27.4 ± 1.3 days for the filters. The CDT group consisted of 17 patients. Among whom we observed, complete dissolution of the intraluminal thrombus was observed in six patients, residual thrombus with a maximum diameter ≤1 cm in nine patients, and residual thrombus with a maximum diameter >1 cm in two patients. The Villalta score decreased from 7.53 ± 0.83 before treatment to 2.06 ± 0.39 after treatment. The thrombus diameter also decreased from 1.46 ± 0.16 cm before treatment to 0.35 ± 0.11 cm after treatment. The retrieval rate of the filters was 88.24% (15/17), and the average filter indwelling time was 19.25 ± 4.5 days. The PCDT group consisted of 11 patients. We observed complete dissolution of the intraluminal thrombus in four patients, residual thrombus with a maximum diameter ≤1 cm in six patients, and residual thrombus with a maximum diameter >1 cm in one patient. The Villalta score decreased from 7.45 ± 0.76 before treatment to 2.09 ± 0.55 after treatment. The thrombus diameter decreased from 1.50 ± 0.21 cm before treatment to 0.33 ± 0.35 cm after treatment, and the rate of filter retrieval was 90.91% (10/11).ConclusionThe three treatments of anticoagulation therapy, CDT, and PCDT were meaningful for preoperative and postoperative thrombolysis and symptom improv
目的:分析下腔静脉滤器血栓形成的治疗方法和疗效:分析下腔静脉滤器血栓(IVCFT)的治疗方法和疗效:本回顾性研究分析了2020年1月至2023年1月在天津医科大学第二医院血管外科接受序贯治疗的47例IVCFT患者的临床资料。根据治疗方法将患者分为三组:抗凝治疗组(AC 组)、抗凝加导管引导溶栓治疗组(CDT 组)和抗凝加 AngioJet 取栓加导管引导溶栓治疗组(PCDT 组)。疗效评估标准主要包括术前和术后临床症状(Villalta评分)、血栓直径、血栓清除率、滤器取栓率、滤器保留时间和尿激酶用量:本研究共纳入 47 例患者,其中男性 31 例(65.9%),女性 16 例(34.1%),平均年龄(72.05±8.32)岁。七名患者使用了 Aegisy 过滤器,四十名患者使用了 Illicium 过滤器。单纯抗凝组共有 19 名患者,其中 5 名患者的腔内血栓完全溶解,3 名患者的残余血栓最大直径≤1 厘米,11 名患者的残余血栓最大直径大于 1 厘米。治疗前的 Villalta 评分为 7.16 ± 0.6,治疗后降至 3.79 ± 0.59。血栓直径从治疗前的平均 1.46 ± 0.2 厘米降至治疗后的平均 0.85 ± 0.14 厘米。滤器取回率为 42.11%(8/19),滤器平均停留时间为 27.4 ± 1.3 天。CDT 组有 17 名患者。我们观察到,其中 6 名患者的腔内血栓完全溶解,9 名患者的残余血栓最大直径≤1 厘米,2 名患者的残余血栓最大直径大于 1 厘米。Villalta 评分从治疗前的 7.53 ± 0.83 降至治疗后的 2.06 ± 0.39。血栓直径也从治疗前的 1.46 ± 0.16 厘米降至治疗后的 0.35 ± 0.11 厘米。滤器取回率为 88.24%(15/17),滤器平均留置时间为 19.25 ± 4.5 天。PCDT 组有 11 名患者。我们观察到 4 名患者的腔内血栓完全溶解,6 名患者的残余血栓最大直径≤1 厘米,1 名患者的残余血栓最大直径大于 1 厘米。Villalta 评分从治疗前的 7.45 ± 0.76 降至治疗后的 2.09 ± 0.55。血栓直径从治疗前的 1.50 ± 0.21 厘米降至治疗后的 0.33 ± 0.35 厘米,滤器取出率为 90.91%(10/11):结论:抗凝治疗、CDT和PCDT三种治疗方法对IVCFT患者术前和术后溶栓及症状改善均有意义。CDT 和 PCDT 的应用优于抗凝疗法,而 CDT 组和 PCDT 组之间无明显差异。抗凝治疗组的滤器取回率最低,CDT 组和 PCDT 组之间无明显差异。
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