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Thermoexpandable Memokath stent: Usage and efficacy in ureteral and urethral strictures in Saudi Arabia. 热膨胀 Memokath 支架:沙特阿拉伯输尿管和尿道狭窄患者的使用情况和疗效。
IF 0.7 Q4 UROLOGY & NEPHROLOGY Pub Date : 2024-01-01 Epub Date: 2024-01-25 DOI: 10.4103/ua.ua_160_22
Omar Buksh, Anfar Jar, Ahmad Khogeer, Hani Alzahrani, Rabea Akram, Mohammad Taher, Mahmoud Al Akra'a, Adel Alammari, Islam Junaid

Objectives: Double J (DJ) stent is widely used in cases of ureteric strictures as a temporary solution; however, it has certain limitations, such as the need for frequent exchange. Alternatively, a long-lasting thermoexpandable stent (Memokath™ 051) has been used to relieve ureteral obstructions in comorbid patients with multiple reported advantages, such as longer durability which avoids the need of frequent exchanges. In addition, it can be used in certain cases of urethral strictures. Our study is the first in the region to report the experience and outcome of Memokath stent with ureteral and urethral strictures.

Materials and methods: After local IRB approval, we retrospectively reviewed records of 21 patients who underwent insertion of Memokath 051 stent in the ureter and Memokath 045 in the urethra between 2013 and 2021. Indications of insertion, indwelling duration, and causes of removal were collected and analyzed by SPSS.

Results: Twenty-one patients received 21 Memokath stents for 11 ureteral strictures and 10 urethral strictures. Fifty-five percent of ureteral strictures were malignant, and 27.3% of the benign ureteric strictures were transplant ureters. Ureteric memokath stents remained functioning for a mean of 16.1 months. Mean indwelling time for transplant ureteric memokath stents was 24.3 months. Total 4 ureteric stents had migrated, 4 stents blocked, and 2 stents were removed as planned and 1 stent removed due to febrile urinary tract infection (UTI). Ten urethral stents remained in place for mean of 14 months. Three stents were removed as planned with resolution of stricture, two were removed due to blockage, three stents had UTI, one was removed due to pain, and one stent remained functioning until the patient expired.

Conclusion: Our outcome is comparable to other published studies, suggesting that ureteric Memokath stent is a better option with adequate indwelling time, especially in transplant ureters, in comparison with DJ stents. In addition, Memokath stents can be used in selected recurrent urethral strictures where surgical reconstruction is not feasible.

目的:双 J(Double J,DJ)支架作为一种临时解决方案被广泛应用于输尿管狭窄的病例中,但它也有一定的局限性,例如需要频繁更换。另外,一种长效热膨胀支架(Memokath™ 051)已被用于缓解合并症患者的输尿管梗阻,据报道这种支架具有多种优点,如使用寿命长,无需频繁更换。此外,它还可用于某些尿道狭窄病例。我们的研究是该地区首次报告 Memokath 支架治疗输尿管和尿道狭窄的经验和结果:经当地国际注册研究委员会批准后,我们回顾性审查了 2013 年至 2021 年期间在输尿管插入 Memokath 051 支架和在尿道插入 Memokath 045 支架的 21 例患者的记录。收集了插入指征、留置时间和移除原因,并用 SPSS 进行了分析:21名患者接受了21枚Memokath支架,用于治疗11处输尿管狭窄和10处尿道狭窄。55%的输尿管狭窄为恶性,27.3%的良性输尿管狭窄为移植性输尿管。输尿管membokath支架的平均使用寿命为16.1个月。移植输尿管membokath支架的平均留置时间为24.3个月。共有 4 个输尿管支架移位,4 个支架堵塞,2 个支架按计划移除,1 个支架因发热性尿路感染(UTI)而移除。10 个尿道支架平均放置了 14 个月。3个支架按计划取出,狭窄得到缓解,2个支架因堵塞而取出,3个支架发生UTI,1个支架因疼痛而取出,1个支架在患者去世前仍在发挥作用:结论:我们的研究结果与其他已发表的研究结果相当,表明与 DJ 支架相比,输尿管 Memokath 支架是一种具有足够留置时间的更好选择,尤其是在移植输尿管中。此外,Memokath 支架还可用于无法进行手术重建的复发性尿道狭窄。
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引用次数: 0
Varicocelectomy outcomes among patients with azoospermia and severe oligasthenoteratozoospermia 无精子症和严重少精子症患者的精索静脉曲张切除术结果
IF 0.7 Q4 UROLOGY & NEPHROLOGY Pub Date : 2023-11-15 DOI: 10.4103/ua.ua_24_23
A. Alkhayal, Sahar Aljumaiah, Ali Alyami, S. Abumelha, K. Alrabeeah
Varicocele is a reversible cause of male infertility. However, there are conflicting data available concerning the benefit of varicocele repair for patients with nonobstructive azoospermia (NOA) and severe oligoasthenoteratozoospermia (OAT). To address the benefit of varicocelectomy in patients with severe OAT and NOA with regard to their semen parameters and surgical sperm retrieval rate in those who underwent testicular sperm extraction (TESE) or testicular sperm aspiration (TESA). This retrospective cohort study was conducted on a sample of 13 patients diagnosed with NOA and severe OAT who underwent varicocelectomy for infertility treatment with no prespecified exclusion criteria. Thirteen patients were enrolled. Five patients were diagnosed with NOA; eight were diagnosed with severe OAT. For improvements in the semen parameters postoperatively, the semen concentration of all patients was significantly increased compared to the preoperative concentration (3.59 ± 10.0.8 vs. 0.25 ± 0.31, P = 0.02) and the remaining parameters were unchanged. Regarding sperm retrieval, three patients underwent TESE and two patients underwent TESA, in which all had positive results. Varicocele repair was found to improve the semen parameters in patients with NOA and severe OAT and produced a successful surgical sperm retrieval rate in all patients who underwent TESA or TESE.
精索静脉曲张是导致男性不育的可逆原因。然而,关于非梗阻性无精子症(NOA)和严重少精子症(OAT)患者进行精索静脉曲张修补术的益处,目前存在相互矛盾的数据。 针对接受睾丸取精术(TESE)或睾丸精子抽吸术(TESA)的重度OAT和NOA患者的精液参数和手术取精率,探讨精索静脉曲张切除术对这些患者的益处。 这项回顾性队列研究对 13 名被诊断为 NOA 和严重 OAT 的患者进行了抽样调查,这些患者均接受了精索静脉曲张切除术以治疗不育症,且未预先确定排除标准。 13 名患者被纳入研究。其中 5 名患者被诊断为 NOA;8 名患者被诊断为严重 OAT。关于术后精液参数的改善,所有患者的精液浓度与术前相比均有显著提高(3.59 ± 10.0.8 vs. 0.25 ± 0.31,P = 0.02),其余参数无变化。在取精方面,三名患者接受了 TESE,两名患者接受了 TESA,结果均为阳性。 研究发现,精索静脉曲张修补术可改善无精子症和重度 OAT 患者的精液参数,所有接受 TESA 或 TESE 的患者的手术取精成功率都很高。
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引用次数: 0
Techniques in minimally invasive transperitoneal pyeloplasty: A compilation 微创经腹膜肾盂成形术的技术:汇编
IF 0.7 Q4 UROLOGY & NEPHROLOGY Pub Date : 2023-11-15 DOI: 10.4103/ua.ua_38_23
C. Mallikarjuna, S. Ghouse, Vijay Kumar Sarma Madduri, M. Bendigeri, B. Enganti, P. Reddy, Gopal Ramdas Tak
Minimally invasive management (laparoscopic/robot assisted) is currently the standard of care for managing pelvi ureteric junction obstruction (PUJO). Open techniques of management of PUJO are well described in literature. However, there appears to be relative lack of description of minimally invasive techniques in the literature. This article is aimed at describing in detail, with images, the various techniques and modifications in laparoscopic or robot-assisted management of PUJO. A review of literature on PubMed was performed and all articles which detailed any technique of minimally invasive pyeloplasty were included. The various techniques of minimally invasive pyeloplasty as well as the authors’ techniques are compiled and described in detail with intraoperative images. Operative techniques of minimally invasive pyeloplasty are not well described in literature. We have attempted to present a comprehensive resource of different techniques of minimally invasive pyeloplasty and the clinical scenarios in which they may be appropriate. This should prove to be a useful reference to the practicing urologist. In this paper, we have compiled the various surgical techniques of treating obstruction at the PUJ of the kidney along with intraoperative photograph.
微创治疗(腹腔镜/机器人辅助)是目前治疗肾盂输尿管连接处梗阻(PUJO)的标准方法。文献中对 PUJO 的开放式治疗技术进行了详细描述。然而,文献中似乎相对缺乏对微创技术的描述。 本文旨在通过图片详细描述腹腔镜或机器人辅助治疗 PUJO 的各种技术和改良方法。 本文对 PubMed 上的文献进行了综述,收录了所有详细介绍微创肾盂成形术技术的文章。 汇编了各种微创肾盂成形术技术以及作者的技术,并结合术中图像进行了详细描述。 微创肾盂成形术的操作技术在文献中没有很好的描述。我们试图提供一份全面的资料,介绍不同的微创肾盂成形术技术及其可能适用的临床场景。这将成为泌尿科医生的有用参考资料。 在本文中,我们汇编了治疗肾脏 PUJ 梗阻的各种手术技术以及术中照片。
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引用次数: 0
Hematuria: Is it useful in predicting renal or ureteral stones in patient presenting to emergency department with flank pain? 血尿:对于因腹部疼痛到急诊科就诊的患者,血尿是否有助于预测肾结石或输尿管结石?
IF 0.7 Q4 UROLOGY & NEPHROLOGY Pub Date : 2023-11-15 DOI: 10.4103/ua.ua_66_23
Mansour Alnazari, A. Bakhsh, H. Shaqroon, Emad S. Rajih, Nizar Abdulaziz Al-Nakshabandi, Danny M. Rabah
The objective of the study was to evaluate hematuria as a diagnostic test for renal and ureteral stones compared with a noncontrast-enhanced computed tomography (CT) scan (gold standard test) in emergency room patients with acute flank pain. In total, 604 patients treated in our emergency department from 2006 to 2011, with a history of flank pain and suspected urolithiasis were included in a retrospective review. All patients were evaluated with a noncontrast-enhanced CT scan and urine analysis. Using the noncontrast CT scan as the gold standard for the evaluation of the presence, number, size, and site (renal or ureteral [upper, middle, and lower]) of the stones, we calculated the sensitivity, specificity, and positive and negative predictive values of hematuria for diagnosing both renal and ureteral stones. Urolithiasis was diagnosed in 388 patients (64%) and 216 patients (36%) had no stones on a noncontrast-enhanced CT scan. The sensitivity, specificity, positive predictive value, and negative predictive value for microhematuria were 77%, 33%, 67%, and 45%, respectively. Microhematuria was more common in patients with ureteral stones only (139 patients) and had a sensitivity of 85% compared to patients with renal stones only (32 patients), with a sensitivity of 55% (P < 0.001). There were no significant differences in the specificity or positive or negative predictive values. Although microhematuria is more sensitive to ureteral stones, the absence of microhematuria does not exclude the possibility of urolithiasis and a noncontrast-enhanced CT scan should be the gold standard diagnostic tool.
这项研究的目的是评估血尿与非造影剂增强计算机断层扫描(CT)扫描(金标准检查)相比,在急性侧腹疼痛的急诊患者中作为肾结石和输尿管结石诊断检查的效果。 2006年至2011年期间,我们急诊科共收治了604名有腹部疼痛病史并疑似患有泌尿系结石的患者,并对这些患者进行了回顾性分析。所有患者均接受了非对比度增强 CT 扫描和尿液分析。我们将非对比CT扫描作为评估结石存在、数量、大小和部位(肾结石或输尿管结石[上段、中段和下段])的金标准,计算了血尿对诊断肾结石和输尿管结石的敏感性、特异性以及阳性和阴性预测值。 388名患者(64%)确诊为尿路结石,216名患者(36%)在非对比度增强CT扫描中未发现结石。微血尿的敏感性、特异性、阳性预测值和阴性预测值分别为 77%、33%、67% 和 45%。微血尿在仅有输尿管结石的患者(139例)中更为常见,敏感性为85%,而仅有肾结石的患者(32例)的敏感性为55%(P < 0.001)。特异性、阳性或阴性预测值没有明显差异。 虽然微血尿对输尿管结石更敏感,但没有微血尿并不能排除尿路结石的可能性,非对比度增强 CT 扫描应作为金标准诊断工具。
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引用次数: 0
Use of artificial stones in training and laboratory studies, have we found the right material? Outcomes of a systematic review from the European School of Urology 在培训和实验室研究中使用人造结石,我们找到正确的材料了吗?欧洲泌尿学院的系统性审查结果
IF 0.7 Q4 UROLOGY & NEPHROLOGY Pub Date : 2023-11-15 DOI: 10.4103/ua.ua_112_22
P. Kallidonis, A. Peteinaris, Domenico Veneziano, Amelia Pietropaolo, K. Pagonis, C. Adamou, A. Vagionis, A. Al-Aown, E. Liatsikos, B. Somani
In this review, we investigated the current literature to find out which artificial stones (AS) are available in endourology, and in which experimental and training schemes they are used. A systematic review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. Twenty-one out of 346 studies met our inclusion criteria and are presented in the current review. The inclusion criteria were the existence of AS and their use for laboratory and training studies. There is a wide variety of materials used for the creation of AS. BegoStone powder (BEGO USA, Lincoln, Rhode Island) and plaster of Paris™ were used in most of the studies. In addition, Ultracal-30 (U. S. Gypsum, Chicago, IL) was also used. Other materials that were used as phantoms were AS created from plaster (Limbs and Things, UK), standardized artificial polygonal stone material (Chaton 1028, PP13, Jet 280; Swarovski), model stones consisting of spheres of activated aluminum (BASF SE, Ludwigshafen am Rhein, Deutschland), Orthoprint (Zhermack, Badia Polesine, Italy), and a combination of plaster of Paris, Portland cement, and Velmix (calcium sulfate powder). Many experimental settings have been conducted with the use of AS. Our research demonstrated nine studies regarding testing and comparison of holmium: yttrium–aluminum–garnet laser devices, techniques, and settings. Six studies were about extracorporeal shock wave lithotripsy testing and settings. Three experiments looked into treatment with percutaneous nephrolithotomy. Additionally, one study each investigated imaging perioperatively for endourological interventions, stone bacterial burden, and obstructive uropathy. AS have been used in a plethora of laboratory experimental studies. Independent of their similarity to real urinary tract stones, they present a tremendous potential for testing and training for endourological interventions.
在这篇综述中,我们对现有文献进行了调查,以了解在腔内泌尿学中可以使用哪些人工结石(AS),以及在哪些实验和培训计划中使用这些人工结石。 我们根据《系统综述和元分析首选报告项目》声明进行了系统综述。在 346 项研究中,有 21 项符合我们的纳入标准,并在本综述中进行了介绍。纳入标准是是否存在强直性脊柱炎及其是否用于实验室和培训研究。 用于制作 AS 的材料种类繁多。大多数研究都使用了 BegoStone 粉末(BEGO USA,Lincoln,Rhode Island)和石膏。此外,还使用了 Ultracal-30(美国石膏公司,伊利诺斯州芝加哥)。其他用作模型的材料包括用石膏制作的 AS(Limbs and Things,英国)、标准化的人造多边形石材(Chaton 1028、PP13、Jet 280;施华洛世奇)、由活性铝球体组成的模型石(BASF SE,德国路德维希港)、Orthoprint(Zhermack,意大利巴迪亚波利辛)以及巴黎石膏、波特兰水泥和 Velmix(硫酸钙粉)的组合。许多实验都使用了 AS。我们的研究显示,有九项研究涉及钇铝石榴石钬激光设备、技术和设置的测试和比较。六项研究涉及体外冲击波碎石的测试和设置。三项实验研究了经皮肾镜碎石术的治疗方法。此外,还有一项研究调查了内镜介入、结石细菌负荷和梗阻性尿病的围手术期成像。 大量实验室实验研究都使用了 AS。由于AS与真实的尿路结石相似,因此AS在测试和培训腔内介入治疗方面具有巨大的潜力。
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引用次数: 0
Techniques of staged laparoscopic orchidopexy for high intra-abdominal testes in children: A systematic review and meta-analysis 分期腹腔镜睾丸切除术治疗儿童腹内高位睾丸的技术:系统回顾和荟萃分析
IF 0.7 Q4 UROLOGY & NEPHROLOGY Pub Date : 2023-11-15 DOI: 10.4103/ua.ua_11_23
N. Borkar, Charu Tiwari, Debajyoti Mohanty, Deepti Vepakomma, Nilesh Nagdeve
Laparoscopic exploration is currently considered the gold standard for managing nonpalpable intraabdominal testes. The problem of short vascular pedicle is addressed in Fowler-Stephen (FS) technique by the division of testicular vessels and in Shehata technique (ST) by traction on testicular vessels. There is a lack of the consensus among pediatric surgeons on the choice of one technique over other. This analysis compares the reported outcomes of staged laparoscopic orchidopexy by ST with the time tested FS technique in managing high intraabdominal undescended testis. The present systematic review and meta-analysis was conducted as per the preferred reporting items for the systematic review and meta-analyses guidelines. Only randomized controlled trials and comparative studies were included. The primary outcomes compared were the incidence of testicular atrophy, testicular retraction/ascent rate, and operative time of Stage I and Stage II orchidopexy. The present analysis was based on three randomized studies with a total of 119 undescended testes in 117 patients satisfying the inclusion criteria. The operative time was less in Stage I FS technique; however, there was no statistically significant difference in operative time of both procedures during the Stage II laparoscopic orchidopexy. Pooled analysis of postintervention testicular atrophy, testicular retraction rate, and duration of postoperative hospitalization showed no difference between both procedures. Both FS and STs are comparable in terms of postintervention testicular atrophy, testicular retraction/ascent; however, the mean operative time is significantly less with FS technique in Stage I laparoscopic orchidopexy.
腹腔镜探查术目前被认为是处理腹腔内无法触及的睾丸的金标准。Fowler-Stephen 技术(FS)通过分割睾丸血管来解决血管蒂短的问题,而 Shehata 技术(ST)则通过牵引睾丸血管来解决血管蒂短的问题。小儿外科医生对选择哪种技术尚未达成共识。本分析比较了在处理腹腔内高位未降睾丸时,采用 ST 和久经考验的 FS 技术进行分期腹腔镜睾丸切除术的结果。 本系统综述和荟萃分析是根据系统综述和荟萃分析指南的首选报告项目进行的。仅纳入了随机对照试验和比较研究。比较的主要结果是睾丸萎缩的发生率、睾丸回缩/下降率以及一期和二期睾丸切除术的手术时间。 本分析基于三项随机研究,共有117名患者的119个未降睾丸符合纳入标准。第一阶段FS技术的手术时间较短;但在第二阶段腹腔镜睾丸切除术中,两种手术的手术时间差异无统计学意义。对干预后睾丸萎缩、睾丸回缩率和术后住院时间的汇总分析表明,两种手术没有差异。 在干预后睾丸萎缩、睾丸回缩/下降方面,FS和ST具有可比性;但在腹腔镜睾丸固定术第一阶段中,FS技术的平均手术时间明显更短。
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引用次数: 0
Day of surgery admission in urology: Patient criteria and the organization required for same-day admission in urology: A retrospective study. 泌尿外科手术入院日期:患者标准和泌尿外科当日入院所需的组织:一项回顾性研究
IF 0.7 Q4 UROLOGY & NEPHROLOGY Pub Date : 2023-10-01 Epub Date: 2023-09-01 DOI: 10.4103/ua.ua_148_22
Hamed Ambusaidi, Muaath Khaled Alshuaibi, Alexandre Colau, Inès Dominique, Martin Mouton, Philippe Sebe

Background: The day of surgery admission (DOSA) has been practiced in surgery for decades, with reports dating as far back as 1909. DOSA policy has potential benefits for the health system and the patient, especially when there is a shortage of health-care resources.

Objective: This study aims to compare DOSA and standard prior admission (D-1) among patients who underwent major urological operations.

Methods: This retrospective study enrolled a total of 206 patients who did not meet the criteria for day care surgery admission. The patients were divided into two groups: those admitted on the same day of surgery and those admitted the day before surgery. Among the participants, 111 (53.8%) were admitted on the same day, while 95 (46.2%) were admitted the day before surgery. We collected data from the electronic health records of these patients, documenting various variables, including patient demographics, type of surgery, admission type and date, intervention date, length of stay, complications, Clavien-Dindo score, and American Society of Anesthesiologists (ASA) score.

Results: We included a total of 206 patients who were admitted for operations in the urology department. The mean age was 70.5 years, and the majority was males (83.5%). Endoscopic procedures were the most common interventions (68%). The most ASA score for the enrolled patients was 2 (56.2%). DOSA was done for 53.8% of the patients, whereas the remaining patients were admitted 1 day before elective surgery. DOSA patients were significantly younger (P = 0.025), had a higher proportion of ASA score 1 (12.7%) and ASA score 3 (26.4%), had significantly fewer postoperative complications (P = 0.002), and had statistically significantly a shorter length of stay (P < 0.001) compared to D-1 admission patients.

Conclusion: In our study, DOSA patients were younger, had a lower prevalence of comorbidities, utilized anticoagulants less frequently, experienced fewer complications, and had significantly shorter hospital stays. Since the DOSA policy is safe and has a lower financial and economic burden on the health-care system, we recommend more urological and surgical centers to implement it.

手术入院日(DOSA)在外科手术中已经实践了几十年,早在1909年就有报道。DOSA政策对卫生系统和患者有潜在的好处,尤其是在医疗资源短缺的情况下。本研究旨在比较接受主要泌尿外科手术的患者的DOSA和标准入院前(D-1)。这项回顾性研究共招募了206名不符合日托手术入院标准的患者。患者被分为两组:手术当天入院的患者和手术前一天入院的患者。在参与者中,111人(53.8%)在同一天入院,95人(46.2%)在手术前一天入院。我们从这些患者的电子健康记录中收集了数据,记录了各种变量,包括患者人口统计、手术类型、入院类型和日期、干预日期、住院时间、并发症、Clavien-Dindo评分和美国麻醉师协会(ASA)评分。我们纳入了206名在泌尿外科接受手术的患者。平均年龄70.5岁,大多数为男性(83.5%)。内镜手术是最常见的干预措施(68%)。入选患者的ASA评分最高为2分(56.2%)。53.8%的患者接受了DOSA,而其余患者在择期手术前1天入院。与D-1入院患者相比,DOSA患者明显更年轻(P=0.025),ASA评分1(12.7%)和ASA评分3(26.4%)的比例更高,术后并发症明显更少(P=0.002),住院时间明显更短(P<0.001)。在我们的研究中,DOSA患者更年轻,合并症的发生率更低,使用抗凝剂的频率更低,并发症更少,住院时间更短。由于DOSA政策是安全的,并且对医疗系统的财政和经济负担较低,我们建议更多的泌尿外科和外科中心实施该政策。
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引用次数: 0
Radiofrequency-assisted, laparoscopic, clampless partial nephrectomy in patients with low-complexity small renal tumors: A retrospective cohort study. 低复杂性小肾脏肿瘤患者的射频辅助腹腔镜无夹肾部分切除术:一项回顾性队列研究。
IF 0.7 Q4 UROLOGY & NEPHROLOGY Pub Date : 2023-07-01 Epub Date: 2023-07-17 DOI: 10.4103/ua.ua_20_23
Ioannis Zachos, Panagiotis Vlachostergios, Lampros Mitrakas, Anastasios Karatzas, Athanasios Oeconomou, Charalampos Mamoulakis, Vasileios Tzortzis

Background: This single-center, retrospective study was performed to investigate the safety and efficacy of radiofrequency-assisted (RF), laparoscopic partial nephrectomy (PN) with zero ischemia in patients with low-complexity small renal tumors.

Materials and methods: Patients with small renal masses (SRMs) who underwent laparoscopic, clampless laparoscopic partial nephrectomy - radiofrequency assisted (LPN-RFA) between January 2016 and June 2020 were studied. Demographics, clinical and pathological characteristics, recurrence-free survival, and overall survival were recorded.

Results: Fifty-two SRMs were excised from corresponding patients using RFA-LPN. The median tumor size was 2.5 cm and all specimens involved low-complexity masses according to the renal nephrometry score. No conversions to radical nephrectomy were recorded. Postoperatively, there were one patient with fever, one with hematuria, and two with urinary leakage treated endoscopically. The majority of tumors (48/52, 86.2%) were clear-cell carcinomas. According to the glomerular filtration rate postoperatively and 12 months' posttreatment, adequate renal function was preserved in all patients. There were no positive surgical margins identified postoperatively and no recurrences during a median follow-up 24 months. All patients were alive at the last follow-up.

Conclusions: This study suggests that RFA laparoscopic clampless PN represents an effective method for managing patients with low-complexity SRMs. It offers adequate intraoperative safety and excellent mid-term oncological control and functional preservation.

背景:这项单中心回顾性研究旨在研究射频辅助(RF)、腹腔镜零缺血肾部分切除术(PN)在低复杂性小肾脏肿瘤患者中的安全性和有效性。材料和方法:研究2016年1月至2020年6月期间接受腹腔镜、无夹腹腔镜射频辅助部分肾切除术(LPN-RFA)的小肾脏肿块(SRM)患者。记录人口统计学、临床和病理特征、无复发生存率和总生存率。结果:应用RFA-LPN从相应的患者身上切除了52个SRM。中位肿瘤大小为2.5cm,根据肾肾测量评分,所有标本均涉及低复杂性肿块。没有记录到转化为根治性肾切除术。术后,有一名患者发烧,一名患者血尿,两名患者尿路渗漏。大多数肿瘤(48/52,86.2%)为透明细胞癌。根据术后和治疗后12个月的肾小球滤过率,所有患者都保持了足够的肾功能。术后无阳性手术切缘,中位随访24个月无复发。所有患者在最后一次随访时均存活。结论:本研究表明,RFA腹腔镜无夹PN是治疗低复杂性SRM患者的有效方法。它提供了足够的术中安全性和良好的中期肿瘤学控制和功能保存。
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引用次数: 0
Small-cell neuroendocrine tumor of the bladder: Unexpected long-term survival with carboplatin-etoposide therapy in a patient with metastatic stage disease. 膀胱小细胞神经内分泌肿瘤:卡铂依托泊苷治疗转移期疾病患者的意外长期生存率。
IF 0.7 Q4 UROLOGY & NEPHROLOGY Pub Date : 2023-07-01 Epub Date: 2023-07-17 DOI: 10.4103/ua.ua_106_22
Eduardo J García Rico, Luis Enrique Ortega Polledo, Alejandro Sánchez Pellejero, Sonia Vázquez Valdés, Isabel Montuenga Fernandez

Neuroendocrine small-cell bladder cancer is an extremely rare and aggressive entity, it constitutes <1% of all bladder malignancies. The small-cell neuroendocrine histological variant has a worse prognosis than the classical subtypes. A case of a 53-year-old female consulting with gross hematuria is presented. Cystoscopy revealed a solid aspect lesion involving the posterior wall and dome that was resected. Histopathological findings showed small-cell pure variant carcinoma, high grade, with lymph, vascular, and perineural infiltration, infiltrating the muscle layer. The extension study made by hole body computed tomography scan, showed evidence of multiple lymph nodes and multiple visceral radiological involvements, with pulmonary, hepatic, and peritoneal implants. More than 10 years later, after receiving nine cycles of carboplatin-etoposide remains in complete remission and without radiological evidence of the disease. This is, to our knowledge, one of the longest disease-free survival cases in metastatic small-cell bladder cancer published nowadays.

神经内分泌小细胞膀胱癌症是一种极为罕见的侵袭性实体,它由
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引用次数: 1
Neurofibroma of the external genitalia, extreme enlargement of the clitoris. 外生殖器神经纤维瘤,阴蒂极度增大。
IF 0.7 Q4 UROLOGY & NEPHROLOGY Pub Date : 2023-07-01 Epub Date: 2023-07-17 DOI: 10.4103/ua.ua_86_22
Razan Almesned, Mohamed Alhagbani, Mohammed Sultan, Mohammed Alshayie, Naif Alqarni, Ahmed Alshammari

Neurofibromatosis of the genitourinary tract is rare, with a prevalence of 0.65%, and it is exceedingly rare to involve the external genitalia. Involvement of the clitoris, labia majora, and prepuce was reported with clitoromegaly being the most frequently occurring. Herein, we are reporting the case of a 6-year-old girl who was diagnosed with a neurofibroma of the clitoris; measuring 9.4 cm in its largest dimension. To the best of our knowledge, this is the largest clitoral neurofibroma reported in the literature. Due to the rarity of such cases and reports limitations in the literature, the diagnosis of neurofibroma of the external genitalia requires a high index of suspicion by health-care providers. Surgical excision and postoperative follow-up for possible recurrence remain the gold standard of management.

泌尿生殖道神经纤维瘤病是罕见的,患病率为0.65%,涉及外生殖器的情况极为罕见。据报道,阴蒂、大阴唇和包皮的受累是最常见的。在此,我们报告了一个6岁女孩的病例,她被诊断为阴蒂神经纤维瘤;最大尺寸为9.4厘米。据我们所知,这是文献中报道的最大的阴蒂神经纤维瘤。由于此类病例的罕见性和文献报道的局限性,外生殖器神经纤维瘤的诊断需要医疗保健提供者的高度怀疑。手术切除和术后可能复发的随访仍然是治疗的黄金标准。
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引用次数: 0
期刊
Urology Annals
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