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Advancements, challenges and future horizons in personalized psychiatry. 个性化精神病学的进步、挑战和未来前景。
IF 73.3 1区 医学 Q1 Medicine Pub Date : 2024-10-01 DOI: 10.1002/wps.21257
Giampaolo Perna,Daniela Caldirola,Alan F Schatzberg,Charles B Nemeroff
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引用次数: 0
Physician-assisted dying in people with mental health conditions - whose choice? 精神疾病患者的医生协助死亡--谁的选择?
IF 73.3 1区 医学 Q1 Medicine Pub Date : 2024-10-01 DOI: 10.1002/wps.21235
M E Jan Wise
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引用次数: 0
Artificial intelligence, consciousness and psychiatry 人工智能、意识和精神病学
IF 73.3 1区 医学 Q1 Medicine Pub Date : 2024-09-16 DOI: 10.1002/wps.21222
Giulio Tononi, Charles Raison
<p>In 1966, a researcher at the Massachusetts Institute of Technology introduced ELIZA, a computer program that simulated a psychotherapist in the Rogerian tradition, rephrasing a patient's words into questions according to simple but effective scripts. This was one of the first (and few) successes of early artificial intelligence (AI). To the dismay of its creator, some people took ELIZA for a real psychotherapist, perhaps because of our innate tendency to project consciousness when we detect intelligence, especially intelligent speech.</p><p>ELIZA's stuttering attempt at AI has now become an immensely eloquent golem. ChatGPT can easily outspeak, outwrite and outperform S. Freud. Because large language models (LLM) benefit from superhuman lexicon, knowledge, memory and speed, artificial brains can now trump natural ones in most tasks.</p><p>ELIZA was named after the flower-girl in G.B. Shaw's play Pygmalion, supposedly because it learned to improve its speech with practice. The original myth of Pygmalion – the sculptor who carved the ideal woman Galatea out of ivory and hoped to bring her to life – is even more apt: does the creation of AI portend artificial consciousness, perhaps even superhuman consciousness? Two camps are beginning to emerge, with radically different answers to this question.</p><p>According to the dominant computational/functionalist stance in cognitive neuroscience, the answer is yes<span><sup>1</sup></span>. Cognitive neuroscience assumes that we are ultimately machines running sophisticated software (that can derail and be reprogrammed). Neural algorithms recognize objects and scenes, direct attention, hold items in working memory, and store them in long-term memory. Complex neural computations drive cognitive control, decision making, emotional reactions, social behaviors, and of course language. In this view, consciousness must be just another function, perhaps the global broadcasting of information<span><sup>2</sup></span> or the metacognitive assessment of sensory inputs<span><sup>3</sup></span>. In this case, whenever computers can reproduce the same functions as our brain, just implemented differently (the functionalists’ “multiple realizability”), they will be conscious like we are.</p><p>Admittedly, despite LLMs sounding a lot like conscious humans nowadays, there is no principled way for determining whether they are already conscious and, if so, in which ways and to what degree<span><sup>1</sup></span>. Nor is it clear how we might establish whether they feel anything (just asking, we suspect, might not do…).</p><p>Cognitive neuroscience typically takes the <i>extrinsic perspective</i>, introduced by Galileo, which has been immensely successful in much of science. From this perspective, consciousness is either a “user illusion”<span><sup>4</sup></span>, or a mysterious “emergent” property. However, as recognized long ago by Leibniz, this leaves experience – what we see, hear, think and feel – entirely unacco
如果人工智能研究所的观点是正确的,那么与占主导地位的计算/功能主义观点形成鲜明对比的是,人工智能缺乏(而且将会缺乏)任何意识的火花:它可能比我们任何人都能说会道,甚至表现得更好(它将 "在功能上等同"),但它不会 "在现象上等同"(它将毫无感觉)5。 用纳格尔(T. Nagel)的话说,计算机无论多么智能,都不会有任何 "成为它的感觉"。就像小脑一样,计算机的意识架构也是错误的。即使它可以完美地执行我们可能关心的所有 "认知 "功能,包括那些我们习惯于认为是人类独有的功能,但所有这些功能都将在 "黑暗中 "展开。如果人工智能研究所是对的,那么将意识归因于人工智能就是一个真正的 "存在 "错误--因为意识是关于 "存在",而不是 "做",而人工智能是关于 "做",而不是 "存在"。在选择性压力下,生物制约因素可能会促进智能与意识的共同进化(通过偏爱高度整合的基质)9。 然而,在更大的背景下,智能与意识可以是双重分离的。我们可以在没有与智力相关的功能能力的情况下获得经验。例如,反应迟钝的病人可能什么也做不了,什么也说不出来,但却拥有丰富的主观体验8。没有意识也可能有高智慧:一个能言善辩的人工智能可能会与我们进行令人兴奋的对话,并以其智慧给我们留下深刻印象,但除了我们听到的句子流之外,并不存在任何其他东西--用 P. 拉金的话来说就是:"没有视觉,没有听觉/没有触觉、味觉或嗅觉,没有任何东西可以用来思考/没有任何东西可以用来爱或联系"。人工智能不仅对心理健康提出了独特而紧迫的挑战,也对人类的状况和我们在自然界中的地位提出了挑战。要么主流的计算/功能主义方法是正确的,我们--高度受限且经常有缺陷的生物机器--很快就会被硅制造的机器所取代,这些机器不仅更好更快,而且还能享受更丰富的内在生活。或者,IIT 是正确的,人类的每一种体验都是一种非凡而珍贵的现象,需要一种非常特殊的神经基质,而这种基质是无法通过模拟其功能来复制的。
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引用次数: 0
Where do neurodevelopmental conditions fit in transdiagnostic psychiatric frameworks? Incorporating a new neurodevelopmental spectrum 神经发育状况在跨诊断精神病学框架中的定位?纳入新的神经发育谱系
IF 73.3 1区 医学 Q1 Medicine Pub Date : 2024-09-16 DOI: 10.1002/wps.21225
Giorgia Michelini, Christina O. Carlisi, Nicholas R. Eaton, Jed T. Elison, John D. Haltigan, Roman Kotov, Robert F. Krueger, Robert D. Latzman, James J. Li, Holly F. Levin-Aspenson, Giovanni A. Salum, Susan C. South, Kasey Stanton, Irwin D. Waldman, Sylia Wilson
Features of autism spectrum disorder, attention-deficit/hyperactivity disorder, learning disorders, intellectual disabilities, and communication and motor disorders usually emerge early in life and are associated with atypical neurodevelopment. These “neurodevelopmental conditions” are grouped together in the DSM-5 and ICD-11 to reflect their shared characteristics. Yet, reliance on categorical diagnoses poses significant challenges in both research and clinical settings (e.g., high co-occurrence, arbitrary diagnostic boundaries, high within-disorder heterogeneity). Taking a transdiagnostic dimensional approach provides a useful alternative for addressing these limitations, accounting for shared underpinnings across neurodevelopmental conditions, and characterizing their common co-occurrence and developmental continuity with other psychiatric conditions. Neurodevelopmental features have not been adequately considered in transdiagnostic psychiatric frameworks, although this would have fundamental implications for research and clinical practices. Growing evidence from studies on the structure of neurodevelopmental and other psychiatric conditions indicates that features of neurodevelopmental conditions cluster together, delineating a “neurodevelopmental spectrum” ranging from normative to impairing profiles. Studies on shared genetic underpinnings, overlapping cognitive and neural profiles, and similar developmental course and efficacy of support/treatment strategies indicate the validity of this neurodevelopmental spectrum. Further, characterizing this spectrum alongside other psychiatric dimensions has clinical utility, as it provides a fuller view of an individual's needs and strengths, and greater prognostic utility than diagnostic categories. Based on this compelling body of evidence, we argue that incorporating a new neurodevelopmental spectrum into transdiagnostic frameworks has considerable potential for transforming our understanding, classification, assessment, and clinical practices around neurodevelopmental and other psychiatric conditions.
自闭症谱系障碍、注意力缺陷/多动障碍、学习障碍、智力障碍以及交流和运动障碍的特征通常在生命早期出现,并与不典型的神经发育有关。DSM-5 和 ICD-11 将这些 "神经发育疾病 "归为一类,以反映它们的共同特征。然而,依赖于分类诊断在研究和临床环境中都会带来巨大的挑战(例如,高并发性、任意的诊断界限、疾病内部的高异质性)。采用跨诊断维度的方法为解决这些局限性、解释神经发育性疾病的共同基础以及描述其与其他精神疾病的共同发生和发展连续性提供了一个有用的替代方案。尽管神经发育特征对研究和临床实践有着根本性的影响,但在跨诊断的精神病学框架中,神经发育特征尚未得到充分考虑。对神经发育性疾病和其他精神疾病的结构进行研究后发现,越来越多的证据表明,神经发育性疾病的特征聚集在一起,形成了一个 "神经发育谱系",其范围从正常到受损都有。对共同的遗传基础、重叠的认知和神经特征、相似的发育过程和支持/治疗策略的有效性进行的研究表明,这一神经发育谱系是有效的。此外,将该谱系与其他精神病学维度一起描述具有临床实用性,因为它能更全面地反映个体的需求和优势,并且比诊断类别更具预后效用。基于这些令人信服的证据,我们认为,将新的神经发育谱纳入跨诊断框架,对于改变我们对神经发育性疾病和其他精神疾病的理解、分类、评估和临床实践具有相当大的潜力。
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引用次数: 0
Aligning the “single law” proposal to the CRPD standard of “will and preferences” 使 "单一法律 "提案符合《残疾人权利公约》的 "意愿和偏好 "标准
IF 73.3 1区 医学 Q1 Medicine Pub Date : 2024-09-16 DOI: 10.1002/wps.21233
Jakov Gather, Matthé Scholten
<p>Galderisi et al<span><sup>1</sup></span> provide an excellent overview of the complex ethical challenges in psychiatry. We subscribe to the authors’ criticism of mental health laws employing a “disorder + risk” schema for involuntary intervention, and their conclusion that these laws discriminate against people with a mental health condition. The authors put forward instead a “single law” proposal in which “involuntary treatment would only be permitted when the objecting person has an impairment of decision-making ability – from any cause – and if treatment is in the person's best interests”<span><sup>1</sup></span>. We strongly endorse the core of this proposal, but would like to suggest three refinements to it.</p><p>First, we propose combining capacity assessment with supported decision-making, to ensure that no one is found to lack decision-making capacity before all reasonably available resources of supported decision-making have been exhausted. Second, we propose replacing the best interests standard by the substituted judgment standard, to achieve a closer alignment of substitute decisions with the will and preferences of the person concerned. Third, we suggest to explicitly define additional criteria for involuntary intervention, to avoid what we will call “the fallacious inference from substitute decision-making to coercion”. The proposed refinements are based on what we call the “combined supported decision-making model”, a model for the informed consent process that provides a non-discriminatory basis for decision-making about involuntary intervention<span><sup>2-5</sup></span>. In this commentary, we focus on the last two refinements.</p><p>Galderisi et al refer to a terminological distinction used in a judgment of the German Federal Constitutional Court to show that the “single law” proposal is consistent with the general principles of the United Nations (UN) Convention on the Rights of People with Disabilities (CRPD) and the wording of Article 12, particularly its insistence that “measures relating to the exercise of legal capacity respect the rights, will and preferences of the person”. The terminological distinction is between “free will” (<i>freier Wille</i>) and “natural will” (<i>natürlicher Wille</i>), which, according to the authors, maps on to the CRPD's distinction between “will” and “preferences”.</p><p>This terminological distinction plays an important role in the legal discourse around the German guardianship law (<i>Betreuungsrecht</i>), which is part of the German Civil Code and applies to all people who need support in managing their own affairs, regardless of whether they have a mental health condition<span><sup>6</sup></span>. The term “free will” (<i>freier Wille</i>) refers to the contemporaneous preferences of a person who possesses decision-making capacity regarding the decision at hand. Expressions of a person's free will must be respected by clinicians and have the status of consent or withdrawal of cons
加尔德里西等人1 对精神病学所面临的复杂伦理挑战进行了精彩的概述。我们赞同作者对采用 "障碍+风险 "模式进行非自愿干预的精神健康法律的批评,以及他们认为这些法律歧视精神疾病患者的结论。作者提出了一个 "单一法律 "的建议,即 "只有当反对者因任何原因导致决策能力受损,并且治疗符合其最大利益时,才允许非自愿治疗 "1 。首先,我们建议将能力评估与辅助决策结合起来,以确保在用尽所有可合理利用的辅助决策资源之前,不会发现任何人缺乏决策能力。第二,我们建议用替代判断标准取代最佳利益标准,使替代决定更符合当事人的意愿和偏好。第三,我们建议明确界定非自愿干预的附加标准,以避免我们称之为 "从替代决策到胁迫的谬误推论"。建议的改进措施是以我们所说的 "综合辅助决策模式 "为基础的,该模式是知情同 意程序的一种模式,它为非自愿干预的决策提供了一个非歧视性的基础2-5 。Galderisi 等人提到了德国联邦宪法法院在一份判决中使用的术语区别,以表明 "单一法律 "提案符合联合国《残疾人权利公约》(CRPD)的一般原则和第 12 条的措辞,特别是该条坚持 "与行使法律能力有关的措施应尊重个人的权利、意愿和偏好"。这种术语上的区别在围绕德国监护法(Betreuungsrecht)的法律讨论中发挥了重要作用,该法是德国民法典的一部分,适用于所有在管理自己事务方面需要帮助的人,无论他们是否有精神健康问题6。自由意志"(freier Wille)一词指的是具有决策能力的人对当前决定的当时选择。临床医生必须尊重一个人的自由意愿,并使其具有同意或撤回同意的地位;也就是说,自由意愿可以使原本不允许的干预行为变得允许,反之亦然。另一方面,"自然意愿"(natürlicher Wille)一词指的是缺乏决策能力的人对当前决定的当时偏好。在医疗决策过程中,必须仔细考虑一个人的自然意愿表达,但在某些情况下,基于其他考虑因素,也可以推翻其自然意愿表达,具体说明如下。它们相当于研究伦理文献中通常所说的 "同意 "和 "反对"。根据德国监护法,任何违背个人自然意愿的医疗干预(即个人不同意的任何医疗干预)都属于 "强制医疗"(ärztliche Zwangsmaßnahme),因此必须遵守严格的条件。尽管作者明确指出,最佳利益标准应根据当事人的信仰和价值观进行主观解释,但我们担心在临床实践中仍会对其进行客观理解。最佳利益标准最初源于家长式的 "医生知道什么是最好的 "方法,而且--尽管作者小心翼翼地进行了限定--临床医生可能会根据 Hawkins7 所称的 "福利医疗主义 "来理解最佳利益标准,即临床医生始终认为,符合当事人最佳利益的做法就是在当事人的情况下具有医学意义的做法。为了避免这种潜在的误解,我们建议用替代判断标准取代最佳利益标准。后一种标准将当事人的意愿和偏好置于中心位置:它将做出当事人如果有决策能力时会做出的治疗决定的任务分配给替代决策者8。
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引用次数: 0
An update from the WPA Section on Anxiety and Obsessive-Compulsive Disorders 世界心理学会焦虑症和强迫症分会提供的最新信息
IF 73.3 1区 医学 Q1 Medicine Pub Date : 2024-09-16 DOI: 10.1002/wps.21255
Naomi A. Fineberg, Dan J. Stein, Katharina Domschke, Eric Hollander, Susanne Walitza, Michael Van Ameringen, Bernardo Dell'Osso, Joseph Zohar
<p>The WPA Section on Anxiety and Obsessive-Compulsive Disorders focuses its activities on a broad range of common and burdensome psychiatric conditions encompassing anxiety and fear-related disorders, obsessive-compulsive and related disorders, and behavioural addiction disorders, including problematic Internet use. This is an exciting area of developing clinical practice, as anxiety and obsessive-compulsive symptoms are increasingly played out in the digital environment.</p><p>The Section provides a forum for clinician scientists and academics to exchange experiences and research advances. It organizes activities at WPA meetings, produces scientific publications and develops guidance on relevant topics, in collaboration with key stakeholder groups such as the World Health Organization (WHO), the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS) (www.icocs.org), the Anxiety Disorders and Obsessive-Compulsive Research Networks of the European College of Neuropsychopharmacology (ECNP) (www.ecnp.eu), and the European Network for Problematic Usage of the Internet (www.internetandme.eu). Here we review some of the Section's recent initiatives and its ambitions for the next five years.</p><p>The ICD-11 has refined and expanded the classification of anxiety disorders, and created two new groupings, one for Obsessive-Compulsive and Related Disorders and another for Disorders due to Addictive Behaviours, including several new diagnoses.</p><p>The ICD-11 grouping of Anxiety or Fear-Related Disorders differentiates fear-related disorders (i.e., phobias related to discrete aversive situations) from anxiety disorders related to a sustained expectation that diffuse aversive events will occur. Separation anxiety disorder and selective mutism have been moved into this grouping.</p><p>Obsessive-compulsive and related disorders often present late for treatment, resulting in poor clinical outcomes. To improve recognition and diagnosis, some members of our Section worked with the WHO to reclassify disparate diagnoses into a single Obsessive-Compulsive and Related Disorders grouping. A seminal field study demonstrated that health care practitioners make more accurate diagnoses of these disorders using the ICD-11 vs. ICD-10<span><sup>1</sup></span>. Moreover, this new classification has advanced research heuristics establishing compulsivity as a transdiagnostic neuropsychological domain.</p><p>Another new ICD-11 grouping was created for Disorders due to Addictive Behaviours. This includes two new disorders – gaming disorder and gambling disorder (on- or off-line) – and a residual category for possible diagnosis of other forms of problematic behaviour with addictive, impulsive and/or compulsive features, including buying or shopping, pornography use, social media use, cyberchondria, digital hoarding, and online streaming.</p><p>Evidence of overlap between compulsive and addictive mechanisms and disorders has led to the establishment of the
世界精神病学协会焦虑症和强迫症分会的活动重点是广泛的常见和负担沉重的精神疾病,包括焦虑和恐惧相关疾病、强迫症和相关疾病,以及行为成瘾疾病,包括有问题的互联网使用。该分会为临床科学家和学者提供了一个交流经验和研究进展的论坛。它与世界卫生组织 (WHO)、国际强迫症学院 (ICOCS) (www.icocs.org)、欧洲神经精神药理学学院 (ECNP) 焦虑症和强迫症研究网络 (www.ecnp.eu) 以及欧洲互联网问题使用网络 (www.internetandme.eu) 等主要利益相关团体合作,在世界心理学会会议上组织活动,出版科学刊物,并就相关主题制定指南。在此,我们回顾了该科最近的一些举措及其未来五年的雄心壮志。ICD-11细化并扩展了焦虑症的分类,并创建了两个新的分类,一个是强迫症及相关障碍,另一个是成瘾行为导致的障碍,其中包括几个新的诊断、ICD-11 将恐惧相关障碍(即与离散的厌恶情境有关的恐惧症)与持续预期会发生弥漫性厌恶事件的焦虑障碍区分开来。分离焦虑症和选择性缄默症也被归入了这一组。强迫症及相关障碍往往很晚才接受治疗,导致临床疗效不佳。为了改进识别和诊断,我们科的一些成员与世界卫生组织合作,将不同的诊断重新归类为单一的强迫症及相关障碍组。一项开创性的实地研究表明,医护人员使用 ICD-11 与 ICD-101 对这些疾病做出的诊断更为准确。此外,这一新的分类方法还推动了研究启发式方法的发展,将强迫症确定为一种跨诊断的神经心理学领域。这包括两个新的疾病--游戏障碍和赌博障碍(在线或离线)--以及一个残余类别,用于诊断其他形式的具有成瘾、冲动和/或强迫特征的问题行为,包括购买或购物、使用色情制品、使用社交媒体、网络成瘾症、数字囤积和在线流媒体。该网络出版了有关诊断、基本机制和评估的重要共识文件2,最终举办了科学与艺术节、一系列教育网络研讨会、在WPA《全球心理健康实践丛书》中出版了一本教科书3,并出版了一本广受欢迎的电子书《学会应对有问题的互联网使用》,该书被翻译成五种语言,免费下载数百次(www.icocs.org)。COVID-19大流行病及其后果使人们更加关注焦虑症和强迫症以及有问题的互联网使用。对于患有上述疾病的人来说,大流行期间固有的感染危险直接影响了临床治疗,因为这增加了他们对社会的回避,阻碍了他们参与重要的治疗活动。僵化的思维和对健康的执着关注导致了公共卫生方面的挑战,如对疫苗的犹豫不决以及难以摆脱 COVID-19 封闭状态。这些挑战和风险包括如何平衡在线和离线时间、滥用和错误信息的传播以及社会分裂等问题。有问题的互联网使用是一个总的类别,代表了各种形式的适应不良的互联网使用,涉及失控或危险的使用模式,对个人和社会的健康和福祉具有深远的有害影响2, 4。认知控制能力尚未发育成熟的青少年和有某些心理健康问题的青少年受这种情况的影响尤为严重,可将其视为自我管理紊乱的标志。重要的是,在 COVID-19 大流行期间,全球有问题的互联网使用率有所增加,在一项荟萃分析中达到了 7.9%,在一些中低收入国家超过了 30%5。
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引用次数: 0
Implementation of the ICD-11 CDDR in China 在中国实施 ICD-11 CDDR
IF 73.3 1区 医学 Q1 Medicine Pub Date : 2024-09-16 DOI: 10.1002/wps.21251
Jiang Long, Na Zhong, Jingjing Huang, Geoffrey M. Reed, Zhen Wang, Yifeng Xu, Min Zhao
<p>Since 2007, China has been actively collaborating with the World Health Organization (WHO) and international colleagues in the revision, field testing, training, and implementation of the ICD-11 chapter on mental, behavioural and neurodevelopmental disorders, and the related Clinical Descriptions and Diagnostic Requirements (CDDR)<span><sup>1</sup></span>. In 2018, the National Health Commission clearly highlighted the importance of the ICD-11 and requested all health care providers in China to use the ICD-11 in their clinical practice<span><sup>2</sup></span>. The ICD-11 CDDR are particularly instrumental to achieving this goal in mental health systems in China, as a vast country with over 30 provincial-level administrative regions and a population of more than 1.4 billion.</p><p>The Shanghai Mental Health Center (SMHC), as a WHO Collaborating Centre for Research and Training in Mental Health and a National Center for Mental Disorders, has led the field testing and implementation of the ICD-11 CDDR in China<span><sup>3</sup></span>. Together with other WHO Collaborating Centers in China, National Centers for Mental Disorders, and prestigious institutions across the country, the SMHC has built a core team for ICD-11 CDDR implementation with over 60 national mental health leaders, including heads of leading mental health institutions and presidents of scientific and professional mental health associations. The implementation of the CDDR in China involves an interrelated and growing set of activities including translation, field testing, research, advocacy and training.</p><p>Translation is the cornerstone of implementing the ICD-11 CDDR in China. The translation process started in 2016, and was a collective effort by experts from Shanghai, Beijing and Changsha, coordinated by the SMHC. It was an iterative process involving eight rounds of review and revision over eight years, with 24 translators and 12 reviewers contributing to the work. The final Chinese version of the ICD-11 CDDR is now available for all mental health professionals in China.</p><p>In conjunction with the translation process, China conducted field testing of the ICD-11 CDDR from 2016 to 2021, following the protocols provided by the WHO. The SMHC was designated as an International Field Study Centre by the WHO, and the president of the SMHC, Min Zhao, was selected as chair of the ICD-11 International Advisory Group on Training and Implementation.</p><p>The Chinese field-testing work involved 2,224 patients, 59 clinical raters, 59 referring clinicians, and 23 research assistants from 10 field testing sites nationwide. The field testing was conducted through a rigorous, multidisciplinary and participatory approach, and the results were submitted to the WHO in 2021 to support the ICD-11 CDDR validation and finalization.</p><p>In June 2018, after most of the content in the CDDR had been finalized, the SMHC coordinated efforts with various government and professional agencies t
此外,由于中国目前缺乏有关博弈障碍的知识和专业技能,国医健委牵头开展了相关研究,开发了中文筛查工具,提供了公共卫生建议7,参与了世界卫生组织关于开发新的博弈障碍国际筛查和诊断工具的合作项目8,并与世界卫生组织和其他重要合作伙伴合作,组织了网络研讨会,以提高评估和治疗博弈障碍的能力。在超过15年的工作中,有几个因素促成了中国成功实施《中国儿童发展报告》。首先,中国政府在制定和推广国家卫生保健国际标准方面发挥着至关重要的作用。政府对 ICD-11 的大力支持为 CDDR 的实施和推广提供了良好的氛围。其次,为在中国实施 CDDR 而确定并授权一个地方倡导者对于提供领导、整体协调、资源动员、培训、质量保证、变革管理和可持续性至关重要。受世卫组织委托,国家卫生健康委员会领导了实施工作,并在应对实施新分类系统的巨大挑战中发挥了重要作用。第三,公众宣传活动和利益攸关方参与举措提高了人们对实施 ICD-11 CDDR 好处的认识。未来,我们将继续推动ICD-11 CDDR在中国的应用和推广,最终实现在中国推广精神卫生保健的目标9。首先,我们将继续在全国范围内开展有关 ICD-11 CDDR 的培训,培训对象包括精神科医生、心理医生、全科医生、护士、社工、卫生管理人员和政策制定者等精神卫生专业人员。其次,将建立一个采用 ICD-11 CDDR 的互动网络,以推动研究、培训和临床举措,从而提高该国精神卫生保健的质量。第三,将开展进一步的活动,如开发新的辅助诊断工具、筛查工具和基于 ICD-11 的教学课程,以促进 ICD-11 和 CDDR 的本地化调整和应用。最后,中国将继续加强与国际精神医学专家和组织的国际合作,促进全球精神卫生事业的发展。
{"title":"Implementation of the ICD-11 CDDR in China","authors":"Jiang Long, Na Zhong, Jingjing Huang, Geoffrey M. Reed, Zhen Wang, Yifeng Xu, Min Zhao","doi":"10.1002/wps.21251","DOIUrl":"https://doi.org/10.1002/wps.21251","url":null,"abstract":"&lt;p&gt;Since 2007, China has been actively collaborating with the World Health Organization (WHO) and international colleagues in the revision, field testing, training, and implementation of the ICD-11 chapter on mental, behavioural and neurodevelopmental disorders, and the related Clinical Descriptions and Diagnostic Requirements (CDDR)&lt;span&gt;&lt;sup&gt;1&lt;/sup&gt;&lt;/span&gt;. In 2018, the National Health Commission clearly highlighted the importance of the ICD-11 and requested all health care providers in China to use the ICD-11 in their clinical practice&lt;span&gt;&lt;sup&gt;2&lt;/sup&gt;&lt;/span&gt;. The ICD-11 CDDR are particularly instrumental to achieving this goal in mental health systems in China, as a vast country with over 30 provincial-level administrative regions and a population of more than 1.4 billion.&lt;/p&gt;\u0000&lt;p&gt;The Shanghai Mental Health Center (SMHC), as a WHO Collaborating Centre for Research and Training in Mental Health and a National Center for Mental Disorders, has led the field testing and implementation of the ICD-11 CDDR in China&lt;span&gt;&lt;sup&gt;3&lt;/sup&gt;&lt;/span&gt;. Together with other WHO Collaborating Centers in China, National Centers for Mental Disorders, and prestigious institutions across the country, the SMHC has built a core team for ICD-11 CDDR implementation with over 60 national mental health leaders, including heads of leading mental health institutions and presidents of scientific and professional mental health associations. The implementation of the CDDR in China involves an interrelated and growing set of activities including translation, field testing, research, advocacy and training.&lt;/p&gt;\u0000&lt;p&gt;Translation is the cornerstone of implementing the ICD-11 CDDR in China. The translation process started in 2016, and was a collective effort by experts from Shanghai, Beijing and Changsha, coordinated by the SMHC. It was an iterative process involving eight rounds of review and revision over eight years, with 24 translators and 12 reviewers contributing to the work. The final Chinese version of the ICD-11 CDDR is now available for all mental health professionals in China.&lt;/p&gt;\u0000&lt;p&gt;In conjunction with the translation process, China conducted field testing of the ICD-11 CDDR from 2016 to 2021, following the protocols provided by the WHO. The SMHC was designated as an International Field Study Centre by the WHO, and the president of the SMHC, Min Zhao, was selected as chair of the ICD-11 International Advisory Group on Training and Implementation.&lt;/p&gt;\u0000&lt;p&gt;The Chinese field-testing work involved 2,224 patients, 59 clinical raters, 59 referring clinicians, and 23 research assistants from 10 field testing sites nationwide. The field testing was conducted through a rigorous, multidisciplinary and participatory approach, and the results were submitted to the WHO in 2021 to support the ICD-11 CDDR validation and finalization.&lt;/p&gt;\u0000&lt;p&gt;In June 2018, after most of the content in the CDDR had been finalized, the SMHC coordinated efforts with various government and professional agencies t","PeriodicalId":23858,"journal":{"name":"World Psychiatry","volume":"65 1","pages":""},"PeriodicalIF":73.3,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142248418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevention, treatment and care of substance use disorders among adolescents. Statement by the UNODC-WHO Informal Scientific Network, 2024 青少年药物使用失调的预防、治疗和护理。联合国毒品和犯罪问题办公室-世界卫生组织非正式科学网络的声明,2024 年
IF 73.3 1区 医学 Q1 Medicine Pub Date : 2024-09-16 DOI: 10.1002/wps.21260
Nora D. Volkow, Michael P. Schaub, Anja Busse, Vladimir Poznyak, Dzmitry Krupchanka, Giovanna Campello
<p>Since 2014, the United Nations Office on Drugs and Crime (UNODC) - World Health Organization (WHO) Informal Scientific Network (ISN) has brought the voice of science to international drug policy discussions at the Commission on Narcotic Drugs, the drug-control policy-making body of the United Nations (UN). The public health dimensions of substance use, including prevention and treatment of substance use disorders, have become prominent in policy debates within the UN system.</p><p>Adolescence, which is the focus of this ISN statement, has been defined as individuals aged between 10 and 19 years<span><sup>1</sup></span>. While no global data on substance use within this full age range could be located, global data among more limited subsets are available. Alcohol is the most commonly used substance among all people 15+ years of age<span><sup>2</sup></span>: 155 million, i.e. more than a quarter (26.5%) of all those aged 15-19, are current drinkers. In addition, the 15-19 age group exhibits higher rates of heavy episodic drinking when compared to the total population of drinkers<span><sup>3</sup></span>. Cannabis is the internationally controlled substance most widely used by adolescents, and its use among 15-16-year-olds varies by region, from less than 3% annual prevalence in Asia to over 17% in Oceania. In most geographical areas, the proportion of adolescents using cannabis is higher than in the general population aged 15-64<span><sup>3</sup></span>.</p><p>Consistent with Sustainable Development Goals<span><sup>4</sup></span> and other international commitments<span><sup>5</sup></span>, UN Member States called for comprehensive, evidence-based prevention of substance use, including early prevention<span><sup>6</sup></span> and available, accessible, diverse, evidence-based treatment and care for children and young people with substance use disorders<span><sup>7</sup></span>. There is a joint responsibility for policy makers, scientists, service providers, and communities to implement effective demand-reduction strategies and to adequately address prevention, treatment and recovery support, as well as measures to reduce the negative health and social consequences of substance use disorders among adolescents.</p><div>The UNODC-WHO ISN makes the following recommendations: <ul><li>Expand the availability and use of evidence-based prevention, treatment and care strategies and interventions for adolescents, and ensure sustainable funding for their implementation.</li><li>Facilitate the availability of evidence-based prevention programs in the public domain with reimbursement schemes, thus allowing for preventive interventions to be inclusive and to address the needs of socio-economically disadvantaged groups, ensuring that minoritized populations, Indigenous groups; and lesbian, gay, bisexual, transgender, queer and questioning (LGBTQ+) people are included.</li><li>Promote population-based and environmental prevention measures, such as enfor
确保人道主义应急准备和响应计划考虑到如何应对药物使用和亚药物使用障碍,包括青少年中的药物使用和亚药物使用障碍,以加强支持系统在这些紧急情况下的应变能力,包括在冲突、战争环境、自然灾害、被迫迁徙和其他流离失所的情况下。应用在线和远程学习元素,加强预防和治疗队伍、投资于青少年药物滥用病症的循证预防和治疗,并投资于相关研究,以加强对青少年药物滥用病症的了解(包括生物心理社会风险和保护因素),从而为不同情况下的青少年制定有效的预防和治疗策略提供依据。科学家、政策制定者、从业人员和社区必须共同努力,实施最有效的预防和治疗战略、政策和干预措施,例如联合国毒品和犯罪问题办公室-世界卫生组织《国际药物滥用预防标准》和联合国毒品和犯罪问题办公室-世界卫生组织《国际药物滥用病症治疗标准》中概述的那些战略、政策和干预措施。国际青少年网络建议决策者将针对青少年药物使用和药物使用失调的循证和道德政策付诸实践,并提供必要的资源,使每个青少年都能达到最高的健康水平。
{"title":"Prevention, treatment and care of substance use disorders among adolescents. Statement by the UNODC-WHO Informal Scientific Network, 2024","authors":"Nora D. Volkow, Michael P. Schaub, Anja Busse, Vladimir Poznyak, Dzmitry Krupchanka, Giovanna Campello","doi":"10.1002/wps.21260","DOIUrl":"https://doi.org/10.1002/wps.21260","url":null,"abstract":"&lt;p&gt;Since 2014, the United Nations Office on Drugs and Crime (UNODC) - World Health Organization (WHO) Informal Scientific Network (ISN) has brought the voice of science to international drug policy discussions at the Commission on Narcotic Drugs, the drug-control policy-making body of the United Nations (UN). The public health dimensions of substance use, including prevention and treatment of substance use disorders, have become prominent in policy debates within the UN system.&lt;/p&gt;\u0000&lt;p&gt;Adolescence, which is the focus of this ISN statement, has been defined as individuals aged between 10 and 19 years&lt;span&gt;&lt;sup&gt;1&lt;/sup&gt;&lt;/span&gt;. While no global data on substance use within this full age range could be located, global data among more limited subsets are available. Alcohol is the most commonly used substance among all people 15+ years of age&lt;span&gt;&lt;sup&gt;2&lt;/sup&gt;&lt;/span&gt;: 155 million, i.e. more than a quarter (26.5%) of all those aged 15-19, are current drinkers. In addition, the 15-19 age group exhibits higher rates of heavy episodic drinking when compared to the total population of drinkers&lt;span&gt;&lt;sup&gt;3&lt;/sup&gt;&lt;/span&gt;. Cannabis is the internationally controlled substance most widely used by adolescents, and its use among 15-16-year-olds varies by region, from less than 3% annual prevalence in Asia to over 17% in Oceania. In most geographical areas, the proportion of adolescents using cannabis is higher than in the general population aged 15-64&lt;span&gt;&lt;sup&gt;3&lt;/sup&gt;&lt;/span&gt;.&lt;/p&gt;\u0000&lt;p&gt;Consistent with Sustainable Development Goals&lt;span&gt;&lt;sup&gt;4&lt;/sup&gt;&lt;/span&gt; and other international commitments&lt;span&gt;&lt;sup&gt;5&lt;/sup&gt;&lt;/span&gt;, UN Member States called for comprehensive, evidence-based prevention of substance use, including early prevention&lt;span&gt;&lt;sup&gt;6&lt;/sup&gt;&lt;/span&gt; and available, accessible, diverse, evidence-based treatment and care for children and young people with substance use disorders&lt;span&gt;&lt;sup&gt;7&lt;/sup&gt;&lt;/span&gt;. There is a joint responsibility for policy makers, scientists, service providers, and communities to implement effective demand-reduction strategies and to adequately address prevention, treatment and recovery support, as well as measures to reduce the negative health and social consequences of substance use disorders among adolescents.&lt;/p&gt;\u0000&lt;div&gt;The UNODC-WHO ISN makes the following recommendations: &lt;ul&gt;\u0000&lt;li&gt;Expand the availability and use of evidence-based prevention, treatment and care strategies and interventions for adolescents, and ensure sustainable funding for their implementation.&lt;/li&gt;\u0000&lt;li&gt;Facilitate the availability of evidence-based prevention programs in the public domain with reimbursement schemes, thus allowing for preventive interventions to be inclusive and to address the needs of socio-economically disadvantaged groups, ensuring that minoritized populations, Indigenous groups; and lesbian, gay, bisexual, transgender, queer and questioning (LGBTQ+) people are included.&lt;/li&gt;\u0000&lt;li&gt;Promote population-based and environmental prevention measures, such as enfor","PeriodicalId":23858,"journal":{"name":"World Psychiatry","volume":"15 1","pages":""},"PeriodicalIF":73.3,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142248420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emotion regulation and mental health: current evidence and beyond 情绪调节与心理健康:现有证据及其他
IF 73.3 1区 医学 Q1 Medicine Pub Date : 2024-09-16 DOI: 10.1002/wps.21244
Matthias Berking
<p>The concept of emotion regulation (ER) is receiving considerable attention in research on psychiatric disorders and their treatment. The popularity of the concept is largely rooted in its premise that deficits in adaptive responses toward undesired affective states contribute to the development and maintenance of most forms of psychopathology.</p><p>This appears obvious when considering psychiatric disorders that are primarily defined by an excess of undesired affective states (e.g., anxiety and mood disorders). For these conditions, it follows almost by definition that the perpetuation or escalation of undesired affective states results from the individual's inability to regulate them.</p><p>However, given that many behavioral and cognitive symptoms of other psychiatric disorders can also be conceptualized as dysfunctional ER strategies, the scope of this paradigm extends much further. Consider, for example, when avoidance is used to reduce anxiety, when alcohol is consumed to numb loneliness, when binge eating serves to distract from emotional anguish, or when appraising a situation as uncontrollable and hopeless is used to reduce the pressure to solve one's problems or to shield oneself from further disappointment. In all these scenarios, behavioral or cognitive strategies yield short-lived relief from undesired affective states. Since the immediate ameliorating effects of these maladaptive strategies reinforce their usage, individuals tend to progressively increase their adoption until criteria for an anxiety, alcohol use, eating or mood disorder, etc. are met.</p><p>Importantly, this trajectory is preventable if the individual realizes the negative mid- and long-term consequences of maladaptive strategies, and pivots to more adaptive ways of coping with undesired affective states. However, any such shift will fail to the extent that the individual lacks effective ER skills. Since all psychiatric disorders are arguably maintained by behaviors and cognitions that initially reduce negative affect, and since a distressed individual is more likely to utilize those strategies in the absence of more adaptive alternatives, it can be hypothesized that all psychiatric disorders are, to a significant degree, perpetuated by insufficient ER skills.</p><p>Drawing on this framework, it can be deduced that patients with psychiatric disorders should benefit from treatments that systematically enhance effective ER skills. Evidence-based ER frameworks, such as the Adaptive Coping with Emotions Model<span><sup>1</sup></span>, posit that such treatments should foster the ability to modify the intensity and duration of undesired affective states, as well as the ability to accept and tolerate such states when modification is not possible.</p><p>Additionally, these treatments should foster so-called preparatory ER skills that facilitate the successful utilization of modification- and acceptance-focused ER skills. Examples of such preparatory skills include
情绪调节(ER)的概念在精神疾病及其治疗的研究中备受关注。这一概念的流行在很大程度上源于它的前提,即对不良情绪状态的适应性反应的缺陷是大多数精神病理学发展和维持的原因。对于这些病症,从定义上就可以看出,不良情绪状态的持续或升级是由于个体无法调节这些情绪状态。然而,鉴于其他精神疾病的许多行为和认知症状也可以被概念化为功能失调的应急反应策略,因此这一范式的范围可以延伸得更远。举例来说,当回避被用来减轻焦虑时,当饮酒被用来麻痹孤独感时,当暴饮暴食被用来转移情绪上的痛苦时,或者当把某种情况评价为无法控制和毫无希望时,被用来减轻解决问题的压力或避免进一步的失望。在所有这些情况下,行为或认知策略都能在短期内缓解不想要的情绪状态。重要的是,如果个体意识到适应不良策略所带来的中长期负面影响,并转而采用适应性更强的方式来应对不良情绪状态,那么这一轨迹是可以避免的。然而,如果个体缺乏有效的应急技能,任何这种转变都会失败。由于所有的精神障碍都可以说是通过最初减少负面情绪的行为和认知来维持的,而且在没有更多适应性替代方法的情况下,痛苦的个体更有可能使用这些策略,因此可以假设,所有的精神障碍在很大程度上都是由于缺乏有效的应急反应技能而长期存在的。以证据为基础的ER框架,如 "适应性情绪应对模式"(Adaptive Coping with Emotions Model1),认为此类治疗应培养患者改变不良情绪状态的强度和持续时间的能力,以及在无法改变不良情绪状态时接受和容忍这种状态的能力。这些准备技能的例子包括意识到自己的感受、充分识别和标记自己的感受、建立一个解释自己目前的感受是如何维持的心理模型,最好是以验证和消除自己的经历的方式,同时也提出具体的工具来促进成功的改变/接受。因此,以ER为重点的治疗还应加强患者的自我支持技能,使其能够坚持不懈地采取适应性策略,尽管这些策略最初可能会加重患者的负面情绪。此外,大量的纵向研究和实验研究表明,这种关联是由急诊室技能缺陷影响心理健康造成的,而不是(完全)相反3。关于特定应急反应技能的重要性,大量证据支持重新评估、接纳和自我同情的有效性4、5。更多的研究表明,明确侧重于提高应急反应技能的治疗方法(如辩证行为疗法)可有效治疗多种精神障碍。文献中更具体的证据表明,专门针对提高ER技能的干预措施(如情感调节训练、情绪调节疗法)可有效治疗多种失调症2、6。最后,在这些研究中观察到的明显中介效应表明,ER技能的提高是症状严重程度减轻的主要驱动力7、8。虽然这些发现令人鼓舞,但精神病理学背景下的ER研究仍然充满了挑战。首先,关键术语的概念定义不够清晰,从情感一词开始,尽管已经有人提出了更具体的定义(如:"情绪"、"情感 "和 "情绪"),但该词仍被广泛用于各种情感状态。
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引用次数: 0
Improving education in psychiatry in an evolving scenario: the activities of the WPA Section on Education in Psychiatry 在不断变化的形势下改进精神病学教育:世界精神病学协会精神病学教育分会的活动
IF 73.3 1区 医学 Q1 Medicine Pub Date : 2024-09-16 DOI: 10.1002/wps.21258
Gaia Sampogna, Hasanen Al-Taiar, Franziska Baessler, Bulent Coskun, Hussien Elkholy, Mariana Pinto da Costa, Rodrigo Ramalho, Andrea Fiorillo
<p>Education of mental health professionals should reflect the changes occurring at scientific, clinical and sociocultural levels, and thus it should be continuously updated. However, in many parts of the world, psychiatric education is still based on a knowledge formed in the last century, and the most recent knowledge on the structure and functioning of the brain, human behaviors and social relationships is missing.</p><p>Moreover, the mission of psychiatrists has evolved over time, from the diagnosis and management of full-blown mental disorders to the identification of a series of mental health problems which are associated with high levels of personal and societal burden. The involvement of experts by experience in policy, clinical and research activities is now acknowledged as a priority<span><sup>1, 2</sup></span>, and the need for a clinical characterization of individual patients beyond diagnosis in order to personalize treatment is widely recognized<span><sup>3, 4</sup></span>. These changes should be taken into account by current educational curricula, but this is not always the case.</p><p>The WPA Section on Education in Psychiatry is committed to improve training and education worldwide, with a special attention to low- and middle-income countries (LMICs), since the future of psychiatry as a discipline strongly depends on the education of the new generations of professionals.</p><p>The Section is updating the type of educational materials available for mental health professionals, and is keen to disseminate them worldwide<span><sup>5</sup></span>. In the last triennium, it has contributed to several educational activities, including the development of informational packages for the general public to decrease misconceptions on people with mental disorders, the update of training curricula for undergraduate medical students, and the organization of educational workshops and meetings for psychiatrists and other mental health professionals.</p><p>In the triennium 2020-2023, following the COVID-19 pandemic – which has represented an unprecedent traumatic event with a detrimental impact on education, training and practice worldwide – the Section has been particularly active in developing and producing new tools to improve education in mental health worldwide<span><sup>6-8</sup></span>.</p><p>The Chair of the Section, in collaboration with the WPA Past-President, has promoted a survey targeting the WPA Zonal Representatives, to identify the educational needs and interests of professionals associated with the WPA<span><sup>9</sup></span>. The main finding has been that these professionals are mostly concerned with public mental health activities and with primary prevention of mental disorders. The main unmet need is the development, implementation and dissemination of educational activities in languages other than English, in order to broaden their accessibility.</p><p>Moreover, the Section has collected experiences on education and tr
研讨会的互动结构使与会者能够交流教育和专业经验,提出问题并获得专家的建议。在主旨发言人中,A. Javed教授和N.A. Javed教授和N. Sartorius教授分享了他们的经验,介绍了如何找到创新的解决方案来改进精神病学的培训和教育,并特别强调了领导力和沟通技巧。该研讨会的成功证实,在线互动教育活动是降低组织和后勤成本的有用工具。该科一直在不断加强与致力于改善精神病学教育和培训的国际组织的合作,如欧洲精神病学协会(EPA)教育委员会和欧洲专科医生联盟(UEMS)。此外,分会主席还积极参加了在布鲁塞尔欧洲议会举行的会议,与来自欧洲医学专家联盟(UEMS)和世界卫生组织(WHO)的代表合作,分享有关精神健康教育机会的想法。我们期待着有更多机会与所有同仁和其他对提升全球精神病学教育感兴趣的利益相关者进行交流。
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World Psychiatry
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