Lauren A Rutter,Lucas J Hamilton,Skylar Wilson,Anne C Krendl,Brea L Perry
{"title":"Sex modifies the relationship between depression and risk for dementia: implications for targeted prevention.","authors":"Lauren A Rutter,Lucas J Hamilton,Skylar Wilson,Anne C Krendl,Brea L Perry","doi":"10.1002/wps.70022","DOIUrl":"https://doi.org/10.1002/wps.70022","url":null,"abstract":"","PeriodicalId":23858,"journal":{"name":"World Psychiatry","volume":"30 1","pages":"154-155"},"PeriodicalIF":73.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145968431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dilip V Jeste,Karen Reimers,Bernardo Ng,Hernán Alessandria,César A Alfonso,Alma Jimenez,Hamid Peseschkian,Manasi Kumar,Renato D Alarcon,Kiran Rabheru
{"title":"Report from the WPA Section on Positive Psychiatry 2015-2025.","authors":"Dilip V Jeste,Karen Reimers,Bernardo Ng,Hernán Alessandria,César A Alfonso,Alma Jimenez,Hamid Peseschkian,Manasi Kumar,Renato D Alarcon,Kiran Rabheru","doi":"10.1002/wps.70025","DOIUrl":"https://doi.org/10.1002/wps.70025","url":null,"abstract":"","PeriodicalId":23858,"journal":{"name":"World Psychiatry","volume":"8 1","pages":"158-159"},"PeriodicalIF":73.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145968444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"What can complex systems theory reveal about social inclusion.","authors":"Helene Speyer","doi":"10.1002/wps.70005","DOIUrl":"https://doi.org/10.1002/wps.70005","url":null,"abstract":"","PeriodicalId":23858,"journal":{"name":"World Psychiatry","volume":"50 1","pages":"84-86"},"PeriodicalIF":73.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145968477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Public health impacts of legalizing recreational cannabis use in Canada and the US.","authors":"Wayne Hall,Benedikt Fischer","doi":"10.1002/wps.70030","DOIUrl":"https://doi.org/10.1002/wps.70030","url":null,"abstract":"","PeriodicalId":23858,"journal":{"name":"World Psychiatry","volume":"17 1","pages":"53-54"},"PeriodicalIF":73.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145968439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seana N Semchishen,Mikkel Højlund,Danielle Lemaire,Ishika Obeegadoo,Nicole G Hammond,Brianna Frangione,Hanna Ogawa,Rebecca Sunderland,Aditya Singh,Gamal Wafy,Mattia Campana,James Sakeah,Karine Brousseau,Christoph U Correll,Elias Wagner,Ian Colman,Marco Solmi
Previous meta-analyses estimating mortality risk in eating disorders (EDs) were restricted to specific disorders or causes of death, and were published before the release of the DSM-5, which introduced significant changes in ED classification. We conducted a PRISMA 2020-compliant systematic review and random-effects meta-analysis assessing all-cause (primary outcome) and cause-specific mortality risk ratio (RR) in cohort/case-control studies of individuals with EDs versus the general population or groups matched by physical and/or psychiatric comorbidities. Meta-regression/subgroup analyses assessed risk aggravating or attenuating factors. Study quality was evaluated using design-specific US National Institutes of Health tools. Altogether, 83 studies were meta-analyzed (patients with EDs: N=307,710, general population controls: N=15,719,076; mean follow-up: 11.96 years, females: 94.35%, mean age: 25.52 years). The quality was rated as "good" in 65.0%, "fair" in 21.7%, and "poor" in 13.3% of the studies. Any ED was associated with higher all-cause mortality vs. the general population (RR=4.92, 95% CI: 4.03-6.00, ranging from RR=5.52, 95% CI: 4.47-6.82 in anorexia nervosa (AN) to non-significant difference in binge eating disorder), as well as with higher suicide-related mortality (RR=8.45, 95% CI: 5.73-12.47, ranging from RR=9.86, 95% CI: 5.63-17.27 in AN to RR=6.15, 95% CI: 2.52-15.04 in bulimia nervosa). Mortality risk from both natural and non-natural causes was also increased in individuals with EDs vs. the general population (RR=3.47, 95% CI: 2.29-5.25, and RR=6.46, 95% CI: 4.62-9.04, respectively). All-cause mortality increased with lower body mass index and shorter follow-ups. Male sex, any psychiatric comorbidity, and comorbid substance use, alcohol use, mood or personality disorders were significantly associated with higher all-cause mortality risk in any ED. These data confirm that EDs are associated with a high all-cause, suicide-related and other cause-specific mortality risk, and indicate that monitoring of physical and psychiatric complications and suicide risk early after diagnosis, particularly in AN, males and individuals with low body mass index, is absolutely needed. Further research is warranted to identify actionable factors that can reduce ED-associated mortality risk.
{"title":"All-cause and cause-specific mortality risk in individuals with eating disorders: systematic review and meta-analysis of relative risk and aggravating or attenuating factors.","authors":"Seana N Semchishen,Mikkel Højlund,Danielle Lemaire,Ishika Obeegadoo,Nicole G Hammond,Brianna Frangione,Hanna Ogawa,Rebecca Sunderland,Aditya Singh,Gamal Wafy,Mattia Campana,James Sakeah,Karine Brousseau,Christoph U Correll,Elias Wagner,Ian Colman,Marco Solmi","doi":"10.1002/wps.70014","DOIUrl":"https://doi.org/10.1002/wps.70014","url":null,"abstract":"Previous meta-analyses estimating mortality risk in eating disorders (EDs) were restricted to specific disorders or causes of death, and were published before the release of the DSM-5, which introduced significant changes in ED classification. We conducted a PRISMA 2020-compliant systematic review and random-effects meta-analysis assessing all-cause (primary outcome) and cause-specific mortality risk ratio (RR) in cohort/case-control studies of individuals with EDs versus the general population or groups matched by physical and/or psychiatric comorbidities. Meta-regression/subgroup analyses assessed risk aggravating or attenuating factors. Study quality was evaluated using design-specific US National Institutes of Health tools. Altogether, 83 studies were meta-analyzed (patients with EDs: N=307,710, general population controls: N=15,719,076; mean follow-up: 11.96 years, females: 94.35%, mean age: 25.52 years). The quality was rated as \"good\" in 65.0%, \"fair\" in 21.7%, and \"poor\" in 13.3% of the studies. Any ED was associated with higher all-cause mortality vs. the general population (RR=4.92, 95% CI: 4.03-6.00, ranging from RR=5.52, 95% CI: 4.47-6.82 in anorexia nervosa (AN) to non-significant difference in binge eating disorder), as well as with higher suicide-related mortality (RR=8.45, 95% CI: 5.73-12.47, ranging from RR=9.86, 95% CI: 5.63-17.27 in AN to RR=6.15, 95% CI: 2.52-15.04 in bulimia nervosa). Mortality risk from both natural and non-natural causes was also increased in individuals with EDs vs. the general population (RR=3.47, 95% CI: 2.29-5.25, and RR=6.46, 95% CI: 4.62-9.04, respectively). All-cause mortality increased with lower body mass index and shorter follow-ups. Male sex, any psychiatric comorbidity, and comorbid substance use, alcohol use, mood or personality disorders were significantly associated with higher all-cause mortality risk in any ED. These data confirm that EDs are associated with a high all-cause, suicide-related and other cause-specific mortality risk, and indicate that monitoring of physical and psychiatric complications and suicide risk early after diagnosis, particularly in AN, males and individuals with low body mass index, is absolutely needed. Further research is warranted to identify actionable factors that can reduce ED-associated mortality risk.","PeriodicalId":23858,"journal":{"name":"World Psychiatry","volume":"15 1","pages":"125-140"},"PeriodicalIF":73.3,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145968446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Norbert Skokauskas,Gary Chaimowitz,Dina Aly El-Gabry,Andrea Fiorillo,Anusha Lachman,Angeles Lopez Geist,Paul Robertson,Hee Jeong Yoo,Bennett L Leventhal
{"title":"Advancing global mental health through education.","authors":"Norbert Skokauskas,Gary Chaimowitz,Dina Aly El-Gabry,Andrea Fiorillo,Anusha Lachman,Angeles Lopez Geist,Paul Robertson,Hee Jeong Yoo,Bennett L Leventhal","doi":"10.1002/wps.21368","DOIUrl":"https://doi.org/10.1002/wps.21368","url":null,"abstract":"","PeriodicalId":23858,"journal":{"name":"World Psychiatry","volume":"3 1","pages":"453-454"},"PeriodicalIF":73.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145059167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mariana Pinto da Costa,Tommaso Squeri,Lucía Péréz Gómez,Bernardo Flôr-Rodrigues
{"title":"Patient involvement in undergraduate psychiatric education: an international survey.","authors":"Mariana Pinto da Costa,Tommaso Squeri,Lucía Péréz Gómez,Bernardo Flôr-Rodrigues","doi":"10.1002/wps.21372","DOIUrl":"https://doi.org/10.1002/wps.21372","url":null,"abstract":"","PeriodicalId":23858,"journal":{"name":"World Psychiatry","volume":"3 1","pages":"459-460"},"PeriodicalIF":73.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145059178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Promoting collaboration, harmonization and dissemination in depression research: the ECNP Depression Meta-Network.","authors":"Andreas Reif, ,Brenda W J H Penninx","doi":"10.1002/wps.21366","DOIUrl":"https://doi.org/10.1002/wps.21366","url":null,"abstract":"","PeriodicalId":23858,"journal":{"name":"World Psychiatry","volume":"45 1","pages":"450-451"},"PeriodicalIF":73.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145059185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christoph U Correll,Samuele Cortese,Marco Solmi,Tommaso Boldrini,Koen Demyttenaere,Katharina Domschke,Paolo Fusar-Poli,Philip Gorwood,Philip D Harvey,Richard S E Keefe,Christine Knaevelsrud,Roman Kotov,Laura Nohr,Taeho Greg Rhee,David Roe,Matthias Rose,Lon S Schneider,Mike Slade,Dan J Stein,Charlene Sunkel,Roger S McIntyre
Improving meaningful outcomes is the main goal of clinical care for mental disorders. Traditionally, the focus in clinical research and practice has been on outcome domains that refer to symptom severity or service use (e.g., hospitalization), relate to categorical diagnoses, and favour clinician-rated measures. More recently, self-rated and dimensional as well as transdiagnostic outcome domains have gained traction, and functioning, quality of life and well-being/life satisfaction, along with the construct of personal recovery, have become a stronger focus. These key multidimensional outcome domains need to be properly defined and assessed. Further, the concepts of "functional" and "personal" recovery need to be differentiated. "Functional recovery" is defined by observed functioning across the domains of self-care, social interactions, leisure time activities, and educational or vocational activities. "Personal recovery" involves the subjective sense of living a personally meaningful life, irrespective of whether symptoms continue, or ongoing/intermittent support is needed. Despite the multi-stakeholder relevance of these outcome domains, no comprehensive account of how to measure them is available. To fill this gap, we provide here an overview of the main tools to assess functioning, quality of life/well-being/life satisfaction, and personal recovery outcomes across mental disorders in adults, aiming to also identify additional needs that should be addressed. We identified tools that can be used in clinical and research practice to assess people with the following mental health conditions: anxiety disorders, bipolar disorder, dementias, eating disorders, major depressive disorder, obsessive-compulsive and related disorders, personality disorders, post-traumatic stress disorder, schizophrenia, and substance use disorders. Both transdiagnostic and disorder-specific measures are described. Suggested tools were selected keeping feasibility and scalability needs in mind. The incorporation of these measures in both research and clinical care will enrich patient assessment as well as treatment planning and evaluation, increasing the likelihood of enhanced outcomes in people living with mental disorders.
{"title":"Beyond symptom improvement: transdiagnostic and disorder-specific ways to assess functional and quality of life outcomes across mental disorders in adults.","authors":"Christoph U Correll,Samuele Cortese,Marco Solmi,Tommaso Boldrini,Koen Demyttenaere,Katharina Domschke,Paolo Fusar-Poli,Philip Gorwood,Philip D Harvey,Richard S E Keefe,Christine Knaevelsrud,Roman Kotov,Laura Nohr,Taeho Greg Rhee,David Roe,Matthias Rose,Lon S Schneider,Mike Slade,Dan J Stein,Charlene Sunkel,Roger S McIntyre","doi":"10.1002/wps.21338","DOIUrl":"https://doi.org/10.1002/wps.21338","url":null,"abstract":"Improving meaningful outcomes is the main goal of clinical care for mental disorders. Traditionally, the focus in clinical research and practice has been on outcome domains that refer to symptom severity or service use (e.g., hospitalization), relate to categorical diagnoses, and favour clinician-rated measures. More recently, self-rated and dimensional as well as transdiagnostic outcome domains have gained traction, and functioning, quality of life and well-being/life satisfaction, along with the construct of personal recovery, have become a stronger focus. These key multidimensional outcome domains need to be properly defined and assessed. Further, the concepts of \"functional\" and \"personal\" recovery need to be differentiated. \"Functional recovery\" is defined by observed functioning across the domains of self-care, social interactions, leisure time activities, and educational or vocational activities. \"Personal recovery\" involves the subjective sense of living a personally meaningful life, irrespective of whether symptoms continue, or ongoing/intermittent support is needed. Despite the multi-stakeholder relevance of these outcome domains, no comprehensive account of how to measure them is available. To fill this gap, we provide here an overview of the main tools to assess functioning, quality of life/well-being/life satisfaction, and personal recovery outcomes across mental disorders in adults, aiming to also identify additional needs that should be addressed. We identified tools that can be used in clinical and research practice to assess people with the following mental health conditions: anxiety disorders, bipolar disorder, dementias, eating disorders, major depressive disorder, obsessive-compulsive and related disorders, personality disorders, post-traumatic stress disorder, schizophrenia, and substance use disorders. Both transdiagnostic and disorder-specific measures are described. Suggested tools were selected keeping feasibility and scalability needs in mind. The incorporation of these measures in both research and clinical care will enrich patient assessment as well as treatment planning and evaluation, increasing the likelihood of enhanced outcomes in people living with mental disorders.","PeriodicalId":23858,"journal":{"name":"World Psychiatry","volume":"56 1","pages":"296-318"},"PeriodicalIF":73.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145059091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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