World Journal of Neuroscience最新文献

{"title":"Psychological Impacts of COVID-19 Pandemic on the Brazilian Population: Occupational Analysis","authors":"L. Teixeira, R. L. Freitas, A. Abad, Juliana Almeida da Silva, Mayra Antonelli-Ponti, C. Mármora, L. A. M. Campos, S. Paiva, Sandra Bastos, José Aparecido da Silva","doi":"10.4236/WJNS.2021.112013","DOIUrl":"https://doi.org/10.4236/WJNS.2021.112013","url":null,"abstract":"Context and objectives: The unexpected pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affected several activities and exposed workers, students and the large mass of unemployed people to an economic and psychological pressure that could lead to various problems, such as anxiety, fear, depression and insomnia, consequently causing impairment of quality of life. Method: A cross-sectional study was conducted using the COVID-19 Peri-Traumatic Distress Index (CPDI) and the Fear of COVID-19 Scale (FCV-19S) to measure peri-traumatic stress and fear, such as psychological reactions during the 2019 coronavirus disease (COVID-19) pandemic. An online spreadsheet was used as a data collection tool to send the questionnaire and scales to a sample of 1,844 participants. Data were analyzed in groups of health professionals, students and teachers, How to cite this paper: Teixeira, L.E.P.P., de Freitas, R.L., Abad, A., da Silva, J.A., Antonelli-Ponti, M., Mármora, C.H.C., Campos, L.A.M., Paiva, S., Bastos, S. and Da Silva, J.A. (2021) Psychological Impacts of COVID-19 Pandemic on the Brazilian Population: Occupational Analysis. World Journal of Neuroscience, 11, 145-160. https://doi.org/10.4236/wjns.2021.112013 Received: April 13, 2021 Accepted: May 28, 2021 Published: May 31, 2021 L. E. P. P. Teixeira et al. DOI: 10.4236/wjns.2021.112013 146 World Journal of Neuroscience and an analysis was performed between unemployed and employed people in order to evaluate the impact of employment on the population’s mental health. Results: All groups presented from moderate to high CPDI and FCV-19S scores, and students and unemployed people had higher levels of stress and fear. Conclusion: COVID-19 pandemic had a significant impact on the Brazilian population, with students and the unemployed showing the highest rates of stress and fear.","PeriodicalId":23878,"journal":{"name":"World Journal of Neuroscience","volume":"93 1","pages":"145-160"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79577002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Neurobiology of Human Super-Communication: Insights for Medicine and Business","authors":"M. Hoffmann","doi":"10.4236/wjns.2021.114021","DOIUrl":"https://doi.org/10.4236/wjns.2021.114021","url":null,"abstract":"Background: Much adversity in our lives can be traced to a communication breakdown. To communicate well, it helps to understand how our brains and its communication hardware and software were assembled in the first place. With these insights, comes a better understanding not only how we can best communicate, but also why it is that way. We can be heard globally but fail to relate to someone beside us. Current modes of human communication: Electronic communication has had stupendous impacts, but cannot accom-plish the fine-tuned, penta-sensory input and multimodal output communication abilities we developed over millions of years as primates. Even those developed before the age of mammals, such as scent and sound, continue to influence and modulate our more dominant vision sense. Hence, vid-eo-conferencing or skyping is unlikely to reliably relay critical pupillometrics, facial micro expressions, body postures, leg movements or scents. Although convenient to dispatch an email, twitter or facebook message at any time during a 24-hour period, the intended message or its impact may not be the optimal one. The remedy exists in knowing what communication tools should be used for what purpose. Much of our interaction involves important decisions, maneuvers, counseling and visionary ideas that are most effectively communicated with the 10 communication modalities we evolved with. Deployment of our communication modalities: An overview of the communication unit assembly process and prodigious communication abilities is presented and how to use these features to propel us back to our super com-municator status amongst our workers, patients, peers and colleagues.","PeriodicalId":23878,"journal":{"name":"World Journal of Neuroscience","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81629000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment Process for Neuropathy Involving Science-Based Clinical Research and Medical Technology Combinations","authors":"Bao Thai","doi":"10.4236/wjns.2021.114019","DOIUrl":"https://doi.org/10.4236/wjns.2021.114019","url":null,"abstract":"","PeriodicalId":23878,"journal":{"name":"World Journal of Neuroscience","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78257441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating Various Neural Features Based on Mechanism of Intricate Balance and Ongoing Activity: Unified Neural Account Underlying and Correspondent to Mental Phenomena","authors":"Tien-Wen Lee, G. Tramontano","doi":"10.4236/WJNS.2021.112014","DOIUrl":"https://doi.org/10.4236/WJNS.2021.112014","url":null,"abstract":"In recent decades, brain science has been enriched from both empirical and computational approaches. Interesting emerging neural features include power-law distribution, chaotic behavior, self-organized criticality, variance approach, neuronal avalanches, difference-based and sparse coding, optimized information transfer, maximized dynamic range for information processing, and reproducibility of evoked spatio-temporal motifs in spontaneous activities, and so on. These intriguing findings can be largely categorized into two classes: complexity and regularity. This article would like to highlight that the above-mentioned properties although look diverse and un-related, but actually may be rooted in a common foundation—excitatory and inhibitory balance (EIB) and ongoing activities (OA). To be clear, description and observation of neural features are phenomena or epiphenomena, while EIB-OA is the underlying mechanism. The EIB is maintained in a dynamic manner and may possess regional specificity, and importantly, EIB is organized along the boundary of phase transition which has been called criticality, bifurcation or edge of chaos. OA is composed of spontaneous organized activity, physiological noise, non-physiological noise and the interacting effect between OA and evoked activities. Based on EIB-OA, the brain may accommodate the property of chaos and regularity. We propose “virtual brain space” to bridge brain dynamics and mental space, and “code driving complexity hypothesis” to integrate regularity and complexity. The functional implication of oscillation and energy consumption of the brain are discussed.","PeriodicalId":23878,"journal":{"name":"World Journal of Neuroscience","volume":"100 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91552099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of Secondary Structure of Extracellular Signal Regulated Kinase (ERK) Interacting Proteins and Their Domain: An in Silico Study","authors":"Kurrey Khuleshwari, Paramanik Vijay","doi":"10.4236/WJNS.2021.111007","DOIUrl":"https://doi.org/10.4236/WJNS.2021.111007","url":null,"abstract":"","PeriodicalId":23878,"journal":{"name":"World Journal of Neuroscience","volume":"465 1","pages":"67-89"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75840560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum Ferritin and D-Dimer as Possible Risk Factors in Ischaemic Stroke in Cancer Patients","authors":"M. Abbas, A. Hady, Mohamed Jawad, Mohamed Mofreh, Samer Salama, W. Mustafa","doi":"10.4236/wjns.2021.114022","DOIUrl":"https://doi.org/10.4236/wjns.2021.114022","url":null,"abstract":"Background: Ischemic stroke is frequently encountered in patients with malignant disease. The pathophysiology of stroke in such cases differs from other subjects with no malignant disease. This study was conducted to compare serum levels of ferritin and d-dimer in cases with ischemic stroke in cancer versus non-cancer patients. Patients and methods: The data of consecutive 264 patients presented with ischemic stroke, confirmed by clinical examina-tion and radiological investigations, were retrospectively reviewed. The included cases were divided into two groups: Group A (non-cancer with stroke, 210 cases) and Group B (cancer with stroke, 54 cases). The collected data included patient demographics, systemic comorbidities, disease and tumor characteristics, in addition to platelet count, serum ferritin and d-dimer. Results: Age, gender, and systemic comorbidities were statistically comparable between the two groups. Additionally, the etiology of stroke and its disability were not statistically different between the two groups. However, the incidence of mortality significantly increased in Group B (25.93% vs. 7.14% of Group A, p = 0.005). Both serum ferritin and d-dimer showed a significant increase in association with cancer (Group B). The former had mean values of 294.54 and 867.87 ng/ml, while the latter had mean values of 463.83 and 888.13 ng/ml in the same two groups, respectively. Conclusion: Serum ferritin and d-dimer showed a significant rise in cancer-associated ischemic stroke. This confirms the role of the hypercoagulable state, associated with malignancy in the development of this morbidity.","PeriodicalId":23878,"journal":{"name":"World Journal of Neuroscience","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91054753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of Present Situation and Influencing Factors of Coping Methods by Parents of Children with Central Nervous System Tumors","authors":"Lan Bai, Qinqin Zhao, C. Xiao, Zhihuan Zhou","doi":"10.4236/wjns.2020.104020","DOIUrl":"https://doi.org/10.4236/wjns.2020.104020","url":null,"abstract":"Background: Central nervous system (CNS) tumors are the most common solid tumors among \u0000children. Due to the severity of the tumors and the complexity of therapeutic \u0000regimes, it is very important to examine whether parents of the children with \u0000CNS tumors have positive coping methods against the disease. This study aims to \u0000analyze the coping methods of the parents and the factors influencing the methods. Methods: A total of 108 parents of brain cancer children admitted from \u0000January 2019 to September 2020 were selected as subjects. After collecting the \u0000general information of the parents, they were studied using the Coping Health \u0000Inventory for Parents (CHIP, Chinese version). \u0000Additionally, their coping pattern and the influencing factors were analyzed. Results: The average scores of the three subscales of the CHIP \u0000were (4.25 ± 0.939), (3.11 ± 1.205) and (3.60 ± 1.187), respectively. \u0000Univariate analysis showed that parents’ education, medical payment methods, \u0000places of residence and economic concerns were the main factors influencing the \u0000coping methods (all P Conclusions: Healthcare staff \u0000should fully evaluate the coping methods adopted by the parents having children \u0000with CNS tumors, take targeted nursing measures accordingly, and assist the \u0000parents in seeking social support and learning disease-related knowledge. In \u0000addition, public education on disease is equally important.","PeriodicalId":23878,"journal":{"name":"World Journal of Neuroscience","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75368619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Musical and Photographic Stimulations on the Symptomatology of Alzheimer’s Disease in Elderly","authors":"Jam Silva, Mayara Ayane da Silva, Maykon Wanderley Leite Alves-da-Silva, Douglas Nijenhuis de Castro, Euclídes Marinho Trindade Filho, J. D. Pai, L. Zambrano, V. B. Felix, Elionai Dias Soares, Camila Conceição Luz Soares, A. J. D. M. S. Filho, Magnúcia de Lima Leite, E. Carvalho, Matheus Santos Freitas, José Claudio da Silva","doi":"10.4236/wjns.2020.104017","DOIUrl":"https://doi.org/10.4236/wjns.2020.104017","url":null,"abstract":"Background: Alzheimer’s disease is a progressive and \u0000neurodegenerative disorder characterized by deterioration of brain \u0000functions. Psychosocial interventions such as music and photographic stimuli \u0000may contribute to cognitive and sensory exercise or rehabilitation. Objective: Evaluate musical and photographic stimuli in elderly people with Alzheimer’s \u0000disease. Methods: It is an uncontrolled clinical trial, before-after \u0000type, eleven subjects composing the sample. Participants were submitted to Katz \u0000Index, Autobiographical Memory Test, GDS-15, Mini-Mental State Examination. The \u0000collection instruments were used on the first and last day of intervention, \u0000individually. There were 2 sessions in the week with duration of 50 minutes \u0000totaling 20 sessions. Data were analyzed by \u0000descriptive and inferential statistics and as variables expressed as \u0000mean standard deviation. Results: There was a significant effect of \u0000cognitive activity (P , it was \u0000observed that a small advance (P = 0.05) of the daily life activities. With the \u0000analysis of GDS-15, it is verified that they are more effective for the \u0000increase of the previous self-estimation of the therapy (P = 0.94). In the \u0000application of the AMT, it is observed that there was a better \u0000recruitment of the memory for the neutral words. Conclusion: Musical and \u0000photographic stimuli had a positive effect on the cognitive level, daily life \u0000activities and autobiographical memory in seniors with Alzheimer’s disease.","PeriodicalId":23878,"journal":{"name":"World Journal of Neuroscience","volume":"103 1","pages":"155-165"},"PeriodicalIF":0.0,"publicationDate":"2020-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84653981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Studies on Parkinson’s-Disease-Linked Genes, Brain Urea Levels and Histopathology in Rotenone Induced Parkinson’s Disease Rat Model","authors":"S. Kavuri, S. Sivanesan, M. Howell, R. Vijayaraghavan, Jayakumar Rajadas","doi":"10.4236/wjns.2020.104021","DOIUrl":"https://doi.org/10.4236/wjns.2020.104021","url":null,"abstract":"Parkinson’s disease (PD) is a debilitating neurological disorder that \u0000affects the aged population globally. This \u0000study aimed to explore how oral- and intraperitoneal-rotenone-induced PD \u0000alters brain urea levels, histopathology, and key Parkinsonism-related genes in the striatum. Hematoxylin and \u0000eosin staining was performed for histopathology assessment and real-time \u0000polymerase chain reaction was performed for gene expression. Rotenone 3 mg/kg \u0000body weight (Rot-3-ip) for 21 days and rotenone 50 mg/kg body weight \u0000(Rot-50-po) for 28 days significantly (p Snca, Becn1 and Prkaa1 gene expression in the striatum. Lewy bodies were visible in \u0000both Rot-3-ip and Rot-50-po rat brains. There were contrasting features in brain and liver \u0000histopathology between the oral and intraperitoneal rotenone treatment groups. However, there was no significant (p \u0000 can have different impacts on the pathological sequence of events based \u0000on the molecular approach.","PeriodicalId":23878,"journal":{"name":"World Journal of Neuroscience","volume":"87 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76055269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychological Impacts Related to Stress and Fear during the COVID-19 Pandemic: Cardiovascular Diseases, Diabetes and Psychological Disorders as Risk Factors","authors":"L. Teixeira, R. L. Freitas, A. Abad, Juliana Almeida da Silva, Mayra Antonelli-Ponti, Sandra Bastos, C. Mármora, L. A. M. Campos, S. Paiva, José Aparecido da Silva","doi":"10.4236/wjns.2020.104019","DOIUrl":"https://doi.org/10.4236/wjns.2020.104019","url":null,"abstract":"Background and Aims: Patients and the general public are under insurmountable psychological pressure which may lead to various psychological \u0000problems, such as anxiety, fear, depression, and insomnia, causing, \u0000consequently, the impaired quality of life. Psychological crisis intervention \u0000plays a pivotal role in the overall deployment of health-related quality of \u0000life and disease control. A novel Severe \u0000Acute Respiratory Syndrome Coronavirus-2 (SARS- CoV-2), \u0000a pathogen of the new coronavirus disease (COVID-19), has affected several \u0000sector activities, including people’s health. To enhance infection control methods, appropriate interventions, and \u0000public health policies, the present study aims to assess the fear and \u0000peri-traumatic stress during the COVID-19 inBrazil. Method: A cross-sectional \u0000survey has been conducted from April 12th to 18th from \u00002020, using the Peri-Traumatic Distress Scale (CPDI) and the Fear Scale \u0000(FCV-19S) aiming to measure the peri-traumatic stress and fear as psychological reactions during the \u0000COVID-19 pandemic. For that purpose, an online spreadsheet was used to \u0000send the questionnaire and scales to a sample of 1844 participants as a \u0000collecting information tool. After the data analysis, the individuals were \u0000separated into 4 groups: Group 1 (1232) population without chronic health \u0000conditions; group 2 (298) patients with previous psychological suffering, group \u00003 (229) patients with cardiovascular diseases, group 4 (71) patients with \u0000diabetes. For analysis, G1 were considered control for comparison \u0000with groups 2, 3 and 4. Results: All the groups showed the CPDI \u0000and FCV-19S increased in comparison with the G1 group. Concerning CPDI, the G 3 \u0000was increased when compared to G1, G2 and G4. The G3 had the FCV-19S higher in \u0000comparison with G1, G2 and G4. The Wilcoxon-Mann-Whitney \u0000test showed a statistical difference between the control group in \u0000comparison with 2 and 3 groups (Mann-Whitney p Conclusion: The COVID-19 pandemic had a significant impact on the \u0000Brazilian population, with patients with heart disease and hypertension presenting the highest numbers of stress and fear, with \u0000numbers comparable and even higher than those who reported previous \u0000psychological distress.","PeriodicalId":23878,"journal":{"name":"World Journal of Neuroscience","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83973574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}