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[Scurvy-A now forgotten previously widespread disease]. [坏血病--一种现在已被遗忘的、以前很普遍的疾病]。
IF 1.1 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-03-01 Epub Date: 2024-10-16 DOI: 10.1007/s10354-024-01054-8
Heinz Flamm

From the sea voyages of the fifteenth century often lasting for years with provisions only of fish, salted meat and biscuits reports came of fatal health alterations of the seamen which were characterized by prostration, loss of teeth and bad breath.Reports on comparable endemic illnesses soon came from the Netherlands, North Germany, the Baltic area, France, Lorraine, Geneva, Bohemia, Moravia, Silesia, Swabia and Russia: the so-called land scurvy. The first medical specification was found in a letter from 1541 by Johann Echt to colleges in the area of Lower Germany, which was published four times. One of the first comprehensive considerations was prepared by the English physician James Lind. Scurvy was also mostly published under many local names, such as Skorbut, Scharbock or Scheurbuik.The pathology of scurvy is dominated by gingival necrosis with loss of teeth, hemorrhages with destruction of the cartilage-bone border especially of the ribs and by subperiosteal hemorrhages of the ribs and long bones.For treatment and prevention of scurvy eating green plants as originally Ficaria verna (lesser celandine, pilewort), Chelidonium majus (great celandine, nipplewort, tetterwort) and Cochlearia officinalis (scurvy grass) proved to be effective. Where green plants were missing decoctions of conifer needles and fresh animal innards were used. When the infantile disease originally named "acute rachitis" in England was diagnosed as scurvy (later Möller-Barlow disease) the treatment of cow's milk for baby food became of great interest.Finally, hexuronic acid, later called ascorbic acid or vitamin C, was found to be a drug that could easily dosed for curing and prevention of scurvy.

十五世纪的海上航行往往持续数年,补给品只有鱼、咸肉和饼干,因此有报告称海员的健康状况发生了致命的变化,表现为虚弱、牙齿脱落和口臭。不久,荷兰、北德意志、波罗的海地区、法国、洛林、日内瓦、波希米亚、摩拉维亚、西里西亚、斯瓦比亚和俄罗斯都出现了类似地方病的报告:即所谓的陆地坏血病。最早的医学规范见于约翰-艾希特(Johann Echt)1541 年写给下德意志地区各学院的一封信,这封信共发表了四次。英国医生詹姆斯-林德(James Lind)编写了最早的全面考虑。坏血病的病理主要是牙龈坏死伴牙齿脱落、出血伴软骨-骨边界(尤其是肋骨)破坏以及肋骨和长骨骨膜下出血。在治疗和预防坏血病方面,食用绿色植物,如最初的 Ficaria verna(小白兰、椿草)、Chelidonium majus(大白兰、乳头草、铁线莲)和 Cochlearia officinalis(坏血病草)被证明是有效的。如果缺少绿色植物,则使用针叶树针和新鲜动物内脏的煎剂。最后,人们发现己酮酸,即后来的抗坏血酸或维生素 C,是一种可以方便地用于治疗和预防坏血病的药物。
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引用次数: 0
Assassination of Elisabeth, Empress of Austria, Queen of Hungary, on 10 September 1898: further additions and minor annotations. 1898 年 9 月 10 日奥地利皇后、匈牙利王后伊丽莎白遇刺:进一步补充和少量注释。
IF 1.1 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-03-01 Epub Date: 2024-09-13 DOI: 10.1007/s10354-024-01053-9
Andreas G Nerlich, Roland Sedivy, Michael E Habicht, Francesco M Galassi, Simon Donell, Viktoria Bogner-Flatz, Oliver K Peschel

Very recently, a comprehensive re-evaluation of the medical facts and observations surrounding the death of Empress Elisabeth "Sisi" of Austria (1837-1898) was published. The Empress was assassinated in Geneva by the anarchist Luigi Luccheni or Lucheni (1873-1910). In parallel to this recent publication, our study group came across an almost unknown letter from Dr. Golay, who was one of the examining doctors of Empress Elisabeth. In this publication we add relevant additions based on this letter and provide further insights regarding the attempts at resuscitation.

最近,出版了一本关于奥地利皇后伊丽莎白-"西西"(1837-1898 年)之死的医学事实和观察结果的全面重新评估报告。皇后是在日内瓦被无政府主义者路易吉-卢切尼(1873-1910 年)暗杀的。在最近出版这本书的同时,我们的研究小组还发现了一封几乎不为人知的戈莱医生的信,他是伊丽莎白皇后的主治医生之一。在本出版物中,我们根据这封信进行了相关补充,并提供了有关复苏尝试的进一步见解。
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引用次数: 0
[The Topical Collection in Wiener Medizinische Wochenschrift]. Wiener Medizinische Wochenschrift的专题文集。
IF 1.1 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-03-01 Epub Date: 2025-03-07 DOI: 10.1007/s10354-025-01075-x
Herbert Kurz
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引用次数: 0
Alcohol and the death of Ludwig van Beethoven: comparison of general biographies to the medical literature. 酒精与路德维希·凡·贝多芬之死:一般传记与医学文献的比较。
IF 1.1 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-03-01 Epub Date: 2023-04-18 DOI: 10.1007/s10354-023-01010-y
Dongwon Lee, William Meredith, Benjamin Lebwohl

Beethoven's autopsy findings of cirrhosis may have been due to alcoholism. This condition may have been underemphasized historically, given its stigma and the incongruence with the often heroic portrayal of Beethoven. We therefore aimed to compare how medical experts and biographers writing for a non-medical audience describe his final illness in the context of alcoholism. English-language biographies were identified using a survey of biographies of Beethoven and supplemented by the authors. English-language medical publications were identified by searching for "Beethoven" in the PubMed® MEDLINE database. We included studies that mentioned Beethoven's final illness and death. We recorded statements regarding alcohol consumption, alcoholism, or alcohol use disorder, and the role of alcohol in Beethoven's death. The most commonly cited final illness was liver disease. Alcohol use was more frequently mentioned in biographies, but alcoholism less so. Alcohol use was invoked as a possible cause of final illness more frequently by medical publications.

贝多芬的尸检结果显示肝硬化可能是由于酗酒所致。这种情况在历史上可能被低估了,因为它的耻辱和与贝多芬的英雄形象不一致。因此,我们的目的是比较医学专家和传记作家如何为非医学读者在酒精中毒的背景下描述他最后的疾病。通过对贝多芬传记的调查和作者的补充,确定了英语传记。通过在PubMed®MEDLINE数据库中搜索“Beethoven”来识别英语医学出版物。我们纳入了提到贝多芬最后的疾病和死亡的研究。我们记录了关于饮酒、酒精中毒或酒精使用障碍的陈述,以及酒精在贝多芬死亡中的作用。最常被提及的临终疾病是肝病。在传记中,饮酒被提及的频率更高,但酗酒被提及的频率较低。医学出版物更频繁地援引酒精使用作为最终疾病的一个可能原因。
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引用次数: 0
Edwin Klebs : Der k. k. Professor Edwin Klebs – Wegbereiter für Theodor Billroth und Robert Koch – zur 190. Wiederkehr seines Geburtstages. Edwin Klebs : The k. k.埃德温-克莱布教授(Theodor Billroth 和 Robert Koch 的先驱)诞辰 190 周年。
IF 1.1 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-03-01 DOI: 10.1007/s10354-024-01036-w
Heinz Flamm
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引用次数: 0
Course of the extensor pollicis longus tendon considering the different functional positions of the wrist and the first ray-an anatomical study. 考虑到手腕和第一射线的不同功能位置的伸拇肌肌腱走向--解剖学研究。
IF 1.1 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-02-01 Epub Date: 2024-08-05 DOI: 10.1007/s10354-024-01052-w
Peter Grechenig, Theresa di Vora, Amir Koutp, Alexandros Andrianakis, Paul Puchwein, Gloria Hohenberger

Background: The aim of this anatomical study was to evaluate the course of the extensor pollicis longus (EPL) tendon, its positional relationship to adjacent structures, and the resulting clinical relevance under consideration of various functional positions.

Materials and methods: Twenty upper extremities from ten adult human cadavers embalmed using Thiel's method were included in this study. The greatest possible movement/slippage of the EPL tendon, the angle at which the tendon wraps around Lister's tubercle, and its course across the extensor carpi radialis longus and brevis (ECRL and ECRB) were recorded and defined in all functional positions.

Results: Our findings demonstrate a high range of motion of the tendon in relation to clinically relevant structures.

Conclusion: Understanding the anatomical course of the EPL tendon, its potential extent of movement, and its resulting positional changes is essential for the diagnosis and surgical treatment of patients with complaints or injuries in the dorsoradial wrist region.

背景:这项解剖学研究的目的是评估伸拇肌肌腱(EPL)的走向、其与邻近结构的位置关系,以及在考虑各种功能位置的情况下由此产生的临床意义:本研究选取了用泰尔法防腐处理的十具成人尸体的 20 个上肢。记录并定义了所有功能体位下 EPL 肌腱的最大可能运动/滑动范围、肌腱缠绕李斯特结节的角度及其穿过桡侧长伸肌和桡侧短伸肌(ECRL 和 ECRB)的路线:结果:我们的研究结果表明,肌腱与临床相关结构之间的运动范围很大:结论:了解 EPL 肌腱的解剖走向、其潜在的运动范围以及由此导致的位置变化,对于诊断和手术治疗腕背侧区域不适或受伤的患者至关重要。
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引用次数: 0
Physical medicine as a relevant player in musculoskeletal medicine. 物理医学是肌肉骨骼医学的重要组成部分。
IF 1.1 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-02-01 Epub Date: 2024-11-19 DOI: 10.1007/s10354-024-01067-3
Richard Crevenna
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引用次数: 0
Feasibility of complex exercise therapy with Standing Ovation and peripheral neuromodulation for gait rehabilitation after incomplete spinal cord injury-a case report. 不完全脊髓损伤后使用站立摇摆和外周神经调控进行步态康复的复合运动疗法的可行性--病例报告。
IF 1.1 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-02-01 Epub Date: 2024-06-05 DOI: 10.1007/s10354-024-01046-8
Anna Pataraia, Winfried Mayr, Jose Luis Vargas Luna, Julia Sternik, Richard Crevenna

Background: Spinal cord injuries (SCIs) are a global concern, annually affecting hundreds of thousands of individuals. Among these cases, incomplete SCIs, allowing some muscle activity below the injury, pose unique challenges. This case study focuses on a 55-year-old male with a moderate incomplete SCI (AIS-D).

Case presentation: After initial treatments and pharmaceutical antispastic therapy, a novel intervention was introduced featuring the Standing Ovation gait exercise system (Standing Ovation GmbH, Hallwang, Austria). This individually tailored system, equipped with a rail system and seat-lifting unit, provided a secure environment for balance training. Over 14 training sessions spanning from October 13, 2021, to March 23, 2022, improvements in functional walking were observed.

Discussion and conclusion: Locomotor improvement in SCI rehabilitation is important; the potential of task-specific gait exercises with the Standing Ovation system in incomplete spinal cord injury seems to be a promising approach. Although promising, these findings call for further systematic studies with larger patient cohorts to strengthen their reliability. Ongoing research endeavors are essential to fully understand the benefits and limitations of this intervention in spinal cord injury rehabilitation.

背景:脊髓损伤(SCI)是一个全球关注的问题,每年影响数十万人。在这些病例中,不完全脊髓损伤(允许损伤部位以下的部分肌肉活动)带来了独特的挑战。本病例研究的重点是一名患有中度不完全 SCI(AIS-D)的 55 岁男性:病例介绍:经过初步治疗和药物抗痉挛治疗后,采用了一种新的干预方法,即 "站立摇摆 "步态锻炼系统(Standing Ovation GmbH,奥地利哈尔旺)。这个为患者量身定制的系统配备了轨道系统和座椅升降装置,为平衡训练提供了一个安全的环境。在2021年10月13日至2022年3月23日的14次训练中,观察到了功能性行走的改善:在脊髓损伤康复中改善运动能力非常重要;在不完全脊髓损伤患者中使用站立摇摆系统进行特定任务步态练习似乎是一种很有前景的方法。尽管这些研究结果很有希望,但仍需要对更大的患者群体进行进一步的系统研究,以加强其可靠性。要充分了解这种干预措施在脊髓损伤康复中的益处和局限性,持续的研究工作至关重要。
{"title":"Feasibility of complex exercise therapy with Standing Ovation and peripheral neuromodulation for gait rehabilitation after incomplete spinal cord injury-a case report.","authors":"Anna Pataraia, Winfried Mayr, Jose Luis Vargas Luna, Julia Sternik, Richard Crevenna","doi":"10.1007/s10354-024-01046-8","DOIUrl":"10.1007/s10354-024-01046-8","url":null,"abstract":"<p><strong>Background: </strong>Spinal cord injuries (SCIs) are a global concern, annually affecting hundreds of thousands of individuals. Among these cases, incomplete SCIs, allowing some muscle activity below the injury, pose unique challenges. This case study focuses on a 55-year-old male with a moderate incomplete SCI (AIS-D).</p><p><strong>Case presentation: </strong>After initial treatments and pharmaceutical antispastic therapy, a novel intervention was introduced featuring the Standing Ovation gait exercise system (Standing Ovation GmbH, Hallwang, Austria). This individually tailored system, equipped with a rail system and seat-lifting unit, provided a secure environment for balance training. Over 14 training sessions spanning from October 13, 2021, to March 23, 2022, improvements in functional walking were observed.</p><p><strong>Discussion and conclusion: </strong>Locomotor improvement in SCI rehabilitation is important; the potential of task-specific gait exercises with the Standing Ovation system in incomplete spinal cord injury seems to be a promising approach. Although promising, these findings call for further systematic studies with larger patient cohorts to strengthen their reliability. Ongoing research endeavors are essential to fully understand the benefits and limitations of this intervention in spinal cord injury rehabilitation.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":" ","pages":"41-43"},"PeriodicalIF":1.1,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11775031/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141248742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of whole-body vibration therapy on pain, functionality, postural stability, and proprioception in patients with subacute and chronic non-specific low back pain: a systematic review. 全身振动治疗对亚急性和慢性非特异性腰痛患者疼痛、功能、姿势稳定性和本体感觉的影响:系统综述
IF 1.1 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-02-01 Epub Date: 2023-11-24 DOI: 10.1007/s10354-023-01026-4
Franziska Remer, Mohammad Keilani, Philipp Kull, Richard Crevenna

Introduction: Non-specific low back pain (NLBP) is a common and clinically significant condition with substantial socioeconomic implications. Whole-body vibration therapy (WBVT) has shown effectiveness in improving pain and sensorimotor function (e.g., in osteoporosis) in previous studies. However, studies had heterogeneous settings. The aim of this study was to assess the effects of WBVT on pain, function, proprioception, and postural stability in patients with subacute and chronic NLBP.

Methods: A systematic literature search was conducted in the scientific databases PubMed, EMBASE, and PEDro (from inception until 17.05.2023). Only prospective controlled and uncontrolled studies were included. Outcome measures assessed were pain intensity, function (activities of daily living and physical function), proprioception, and postural stability.

Results: A total of 12 original articles (n = 821) were included in the analysis. Ten of the studies were randomized controlled trials, one study had a crossover design, and one study had a one-group pre-post study design. The studies compared WBVT vs. no intervention, WBVT vs. basic physical therapy, WBVT vs. core stabilization exercises with and without respiratory resistance, WBVT vs. lumbar extension exercises, and WBVT vs. whole body electromyostimulation training. The treatment approaches varied in terms of duration (2-18 weeks), frequency (2-3 times per week, two applications with a 2-week break), vibration frequency (5-30 Hz), type of exercises (WBVT with or without static or dynamic exercises), and vibration direction (horizontal and vertical). Significant pain reduction was observed in all 10 studies that investigated pain levels. Significant improvement in daily activity function was reported in five of the six studies that investigated daily function, while improvement in physical function was observed in all four studies that investigated physical function. Improvement in proprioception was reported in all three studies that investigated proprioception, and significant improvement in postural stability was observed in four out of six studies that investigated postural stability. No adverse events or side effects related to WBVT were reported.

Conclusion: The majority of the included studies demonstrated significant pain reduction, improvement in physical and daily functioning, and enhanced proprioception. Improvement in postural stability was less consistent. WBVT appears to be a safe and effective treatment modality for subacute and chronic NLBP when used within a multimodal approach. Future research should focus on standardized settings including assessment methods, treatment regimens, frequencies, and intensities.

非特异性腰痛(NLBP)是一种常见且具有临床意义的疾病,具有重要的社会经济意义。在先前的研究中,全身振动疗法(WBVT)已显示出改善疼痛和感觉运动功能(例如骨质疏松症)的有效性。然而,研究有异质设置。本研究的目的是评估WBVT对亚急性和慢性NLBP患者疼痛、功能、本体感觉和姿势稳定性的影响。方法:系统检索PubMed、EMBASE、PEDro等科学数据库(建库至2023年5月17日)的文献。仅纳入前瞻性对照和非对照研究。评估的结果包括疼痛强度、功能(日常生活活动和身体功能)、本体感觉和姿势稳定性。结果:共纳入12篇原创文章(n = 821)。其中10项研究为随机对照试验,1项研究为交叉设计,1项研究为一组研究前后设计。这些研究比较了WBVT与无干预、WBVT与基础物理治疗、WBVT与有呼吸阻力和无呼吸阻力的核心稳定运动、WBVT与腰椎伸展运动、WBVT与全身肌电刺激训练。治疗方法在持续时间(2-18周)、频率(每周2-3次,两次应用,休息2周)、振动频率(5-30 Hz)、练习类型(WBVT有或没有静态或动态练习)和振动方向(水平和垂直)方面各不相同。在调查疼痛水平的所有10项研究中,都观察到明显的疼痛减轻。在调查日常功能的六项研究中,有五项研究报告了日常活动功能的显著改善,而在调查身体功能的所有四项研究中都观察到身体功能的改善。在调查本体感觉的所有三项研究中都报道了本体感觉的改善,并且在调查姿势稳定性的六项研究中,有四项研究观察到姿势稳定性的显着改善。无与WBVT相关的不良事件或副作用报道。结论:大多数纳入的研究显示疼痛明显减轻,身体和日常功能改善,本体感觉增强。姿势稳定性的改善不太一致。当采用多模式方法时,WBVT似乎是亚急性和慢性NLBP的一种安全有效的治疗方式。未来的研究应侧重于标准化设置,包括评估方法、治疗方案、频率和强度。
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引用次数: 0
Sentinel fracture: the necessity of improved post-fracture care. 前哨骨折:改善骨折后护理的必要性。
IF 1.1 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-02-01 Epub Date: 2024-11-29 DOI: 10.1007/s10354-024-01066-4
Katharina Kerschan-Schindl, Harald Widhalm, Anna Pataraia, Peter Nicolakis, Martin Frossard, Mohammad Keilani, Michael Mickel, Stefan Hajdu, Richard Crevenna

Fragility fractures caused by osteoporosis, the most common metabolic bone disease, place a significant burden on affected individuals and impose substantial economic costs. A fragility fracture implies an imminent elevated risk for subsequent fractures, particularly in the short term. Therefore, osteoporosis must be addressed in the event of a sentinel fracture, if not already previously treated. Regardless of whether the fracture is treated conservatively or surgically, post-fracture care is particularly important. Early mobilization followed by fall risk assessment and the initiation of adequate bone-specific medication are essential milestones in preventing subsequent fractures. Monitoring patients increases adherence to bone-specific medication and fall prevention strategies. Comprehensive post-fracture care is important and should be performed by a multidisciplinary team. Coordinated care models, such as the fracture liaison service (FLS), have shown enhancements in the initiation of and adherence to secondary prevention of fragility fractures. Despite recommendations by several guidelines including that published by the Austrian Society for Bone and Mineral Research, only one fracture liaison service has been implemented in Austria.

骨质疏松症引起的脆性骨折是最常见的代谢性骨病,给患者带来了沉重的负担,并造成了巨大的经济成本。脆性骨折意味着后续骨折的风险增加,特别是在短期内。因此,骨质疏松症必须在前哨骨折的情况下处理,如果以前没有治疗过的话。无论是保守治疗还是手术治疗,骨折后的护理都尤为重要。早期活动,随后进行跌倒风险评估和开始适当的骨特异性药物治疗是预防后续骨折的重要里程碑。监测患者可以增加对骨骼特异性药物和预防跌倒策略的依从性。综合骨折后护理很重要,应由多学科团队进行。协调护理模式,如骨折联络服务(FLS),在脆弱性骨折二级预防的启动和坚持方面显示出增强。尽管奥地利骨骼和矿物研究协会发布了一些指导方针,但奥地利只实施了一项骨折联络服务。
{"title":"Sentinel fracture: the necessity of improved post-fracture care.","authors":"Katharina Kerschan-Schindl, Harald Widhalm, Anna Pataraia, Peter Nicolakis, Martin Frossard, Mohammad Keilani, Michael Mickel, Stefan Hajdu, Richard Crevenna","doi":"10.1007/s10354-024-01066-4","DOIUrl":"10.1007/s10354-024-01066-4","url":null,"abstract":"<p><p>Fragility fractures caused by osteoporosis, the most common metabolic bone disease, place a significant burden on affected individuals and impose substantial economic costs. A fragility fracture implies an imminent elevated risk for subsequent fractures, particularly in the short term. Therefore, osteoporosis must be addressed in the event of a sentinel fracture, if not already previously treated. Regardless of whether the fracture is treated conservatively or surgically, post-fracture care is particularly important. Early mobilization followed by fall risk assessment and the initiation of adequate bone-specific medication are essential milestones in preventing subsequent fractures. Monitoring patients increases adherence to bone-specific medication and fall prevention strategies. Comprehensive post-fracture care is important and should be performed by a multidisciplinary team. Coordinated care models, such as the fracture liaison service (FLS), have shown enhancements in the initiation of and adherence to secondary prevention of fragility fractures. Despite recommendations by several guidelines including that published by the Austrian Society for Bone and Mineral Research, only one fracture liaison service has been implemented in Austria.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":" ","pages":"3-10"},"PeriodicalIF":1.1,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11774949/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142755718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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