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Frequency distribution of health disorders in primary care-its consistency and meaning for diagnostics and nomenclature. 初级保健中健康疾病的频率分布--其一致性及其对诊断和命名的意义。
IF 1.1 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-07-22 DOI: 10.1007/s10354-024-01049-5
Waltraud Fink, Otto Kasper, Gustav Kamenski, Sonja Zehetmayer, Dietmar Kleinbichler, Martin Konitzer

RN Braun observed that frequencies of health disorders in general practice are so consistent that he called his discovery "Case Distribution Law". Our study compares morbidity data from methodologically similar surveys in primary care practices over a period of fifty years. Frequency ranks were determined for each observation period and the first 150 ranks were compared with Spearman's correlation coefficients. All correlations were consistently positive. Frequency ranks were strikingly similar for surveys carried out at approximately the same time, especially when nomenclatural matching had been carried out before data collection. Ranks were also very similar where clear disease classifications were possible, but less so for non-specific symptoms.The consistency of the distribution of health disorders helps develop diagnostic strategies (diagnostic protocols) and appropriate labeling for non-specific, diagnostically open symptom classifications. According to Braun's considerations, the regularity of case distribution plays an important role in the professionalization of primary care.

RN Braun 发现,全科医疗中健康疾病的发生频率非常一致,因此他将自己的发现称为 "病例分布定律"。我们的研究比较了五十年来方法相似的初级保健实践调查中的发病率数据。确定了每个观察期的频率等级,并用斯皮尔曼相关系数比较了前 150 个等级。所有相关系数始终为正。在大致相同时间进行的调查中,频率排名惊人地相似,尤其是在数据收集前进行了术语匹配的情况下。健康失调分布的一致性有助于制定诊断策略(诊断方案),并为非特异性、诊断上开放的症状分类贴上适当的标签。根据布劳恩的观点,病例分布的规律性在初级保健的专业化方面发挥着重要作用。
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引用次数: 0
Pulmonary presentation and coil marcation of dirofilaria lung coin nodes - case report. 双丝酵母菌肺硬币结节的肺部表现和线圈大理石化--病例报告。
IF 0.9 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-06-05 DOI: 10.1007/s10354-024-01044-w
Tomislav Bečejac, Luka Marcelić, Damir Danolić, Marko Vrančić, Dorian Hiršl, Dubravko Jalšovec

Clinicians face significant diagnostic challenges when dealing with nodal lesions of the lung. The majority of lung nodules are benign; however, a significant number can be cancerous. Dirofilaria infestation should also be considered in the differential diagnosis of nodal lung lesions. Most patients with Dirofilaria infestation are asymptomatic. To determine the etiology of nodal lung infiltrations, procedures like radiological imaging, bronchoscopy, endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA), transthoracic biopsy (TTB), tumor markers, nonspecific serological tests, or surgical removal of the lung coin lesions can be performed. Coil marking of the smaller lung lesions under computed tomography (CT) guidance is a helpful tool in determining the position and localization of the nodal lung lesions. Video-assisted thoracoscopic surgery (VATS) or robot-assisted thoracoscopic surgery (RATS) wedge resection is a diagnostic and therapeutic method of choice. No additional treatment of Dirofilaria other than wedge resection of the lung is necessary.

临床医生在处理肺结节病变时面临着巨大的诊断挑战。大多数肺结节是良性的,但也有相当一部分可能是癌症。在肺结节病变的鉴别诊断中,也应考虑到双鞭毛虫感染。大多数感染狄罗非丝虫的患者没有症状。为确定结节性肺浸润的病因,可进行放射成像、支气管镜检查、支气管内超声经支气管针吸术(EBUS-TBNA)、经胸活检(TTB)、肿瘤标记物、非特异性血清学检测或手术切除肺部硬币病变等程序。在计算机断层扫描(CT)引导下对较小的肺部病灶进行线圈标记,有助于确定肺部结节病灶的位置和定位。视频辅助胸腔镜手术(VATS)或机器人辅助胸腔镜手术(RATS)楔形切除术是诊断和治疗的首选方法。除肺部楔形切除术外,无需对狄罗非丝虫进行其他治疗。
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引用次数: 0
Application value of an artificial intelligence-based diagnosis and recognition system in gastroscopy training for graduate students in gastroenterology: a preliminary study. 基于人工智能的诊断和识别系统在消化内科研究生胃镜培训中的应用价值:初步研究。
IF 1.1 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-06-01 Epub Date: 2023-09-07 DOI: 10.1007/s10354-023-01020-w
Peng An, Zhongqiu Wang

Objective: This study aimed to discuss the application value of an artificial intelligence-based diagnosis and recognition system (AIDRS) in the teaching activities for Bachelor of Medicine and Bachelor of Surgery (MBBS) in China. The learning performance of graduate students in gastroenterology during gastroscopy training with and without AIDRS was assessed.

Methods: The study recruited 32 graduate students of the gastroenterology program at Jiangsu province hospital of Chinese medicine and Xiangyang No. 1 People's Hospital from March 2018 to March 2022 and randomly divided them into AIDRS (n = 16) and non-AIDRS (n = 16) groups. The AIDRS software was used for real-time monitoring of blind spots of gastroscopy to aid in lesion diagnosis and recognition in the AIDRS group. Only a conventional gastroscopic procedure was implemented in the non-AIDRS group. The final performance score, success rate of gastroscopy, lesion detection rate, and pain score of patients were compared between the two groups during gastroscopy. A self-prepared teaching and learning satisfaction questionnaire was administered to the two groups of students.

Results: The AIDRS group had a higher final performance score (92.60 ± 2.83 vs. 89.21 ± 3.57, t = 2.98, P < 0.05), a higher success rate of gastroscopy (448/480 vs. 417/480, χ2 = 11.23, P < 0.05), and a higher detection rate of lesions (51/52 vs. 41/53, χ2 = 8.56, P < 0.05) compared with the non-AIDRS group. The pain scores of patients were lower in the AIDRS group than in the non-AIDRS group (3.40 [2.23, 3.98] vs. 4.45 [3.72, 4.75], Z = 3.04, P < 0.05). Besides, the average time for gastroscopy was lower in the AIDRS group than in the non-AIDRS group (7.15 ± 1.24 vs. 8.21 ± 1.26, t = 2.38, P = 0.02). The overall satisfaction level with the teaching program was higher in the AIDRS group (43.51 ± 2.29 vs. 40.93 ± 2.07, t = 3.33, P < 0.05).

Conclusion: In the context of medicine-education cooperation, AIDRS offered valuable assistance in gastroscopy training and increased the success rate of gastroscopy and teaching and learning satisfaction. AIDRS is worthy of wider-scale promotion.

研究目的本研究旨在探讨基于人工智能的诊断和识别系统(AIDRS)在中国医学学士和外科学学士(MBBS)教学活动中的应用价值。研究评估了消化内科研究生在使用和未使用人工智能诊断与识别系统进行胃镜检查培训期间的学习表现:该研究于2018年3月至2022年3月在江苏省中医院和襄阳市第一人民医院招收32名消化内科专业研究生,将其随机分为AIDRS组(n=16)和非AIDRS组(n=16)。AIDRS组采用AIDRS软件实时监测胃镜检查盲区,辅助病灶诊断和识别。非 AIDRS 组仅实施传统胃镜手术。比较两组患者在胃镜检查过程中的最终表现评分、胃镜检查成功率、病灶检出率和疼痛评分。对两组学生进行了自编的教学满意度问卷调查:结果:AIDRS 组的最终成绩得分更高(92.60 ± 2.83 vs. 89.21 ± 3.57,t = 2.98,P 2 = 11.23,P 2 = 8.56,P 结论:AIDRS 组的最终成绩得分更高(92.60 ± 2.83 vs. 89.21 ± 3.57,t = 2.98,P 2 = 11.23,P 2 = 8.56):在医教合作背景下,AIDRS 为胃镜检查培训提供了有价值的帮助,提高了胃镜检查的成功率和教学满意度。AIDRS 值得大范围推广。
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引用次数: 0
Education of non-medical practitioners in Germany-an analysis of course subjects of specialized schools. 德国非医疗从业人员的教育--专科学校课程科目分析。
IF 0.9 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-06-01 Epub Date: 2021-12-13 DOI: 10.1007/s10354-021-00896-w
Lea Hoffmeister, Jutta Huebner, Christian Keinki, Karsten Muenstedt

In Germany, non-medical practitioners (NMPs; in German: Heilpraktiker) offer a broad range of complementary and alternative (CAM) methods. Our aim was to characterize schools for NMPs in Germany in terms of basic (medical) training and advanced education. We found 165 schools for NMPs in a systematic web-based search. As the medical board examination NMPs must take before building a practice exclusively tests their knowledge in conventional medicine, schools hardly include training in CAM methods. Only few schools offered education on CAM methods in their NMP training. Although NMP associations framed requirements for NMP education, 83.0% (137/165) of schools did not meet these requirements. Patients and physicians should be aware of the lack of training and consequent risks, such as harm to the body, delay of necessary treatment, and interaction with conventional drugs. Disestablishing the profession of NMPs might be a reasonable step.

在德国,非医疗从业人员(NMPs;德语:Heilpraktiker)提供广泛的补充和替代(CAM)方法。我们的目的是从基础(医学)培训和高级教育的角度来描述德国非执业医师学校的特点。通过系统性的网络搜索,我们找到了 165 所国家执业医师学校。由于非执业医师在开业前必须参加医学委员会的考试,而考试只测试他们的常规医学知识,因此学校几乎不包括 CAM 方法的培训。只有少数学校在其 NMP 培训中提供 CAM 方法教育。虽然非执业医师协会制定了非执业医师教育的要求,但 83.0%(137/165)的学校没有达到这些要求。患者和医生应该意识到缺乏培训以及由此带来的风险,例如对身体的伤害、延误必要的治疗以及与传统药物的相互作用。取消非药物治疗师职业可能是一个合理的步骤。
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引用次数: 0
Rare non-serous fallopian tube cancers: institutional experience and literature review. 罕见的非浆液性输卵管癌:机构经验和文献综述。
IF 0.9 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-06-01 Epub Date: 2023-11-28 DOI: 10.1007/s10354-023-01027-3
Dmitrii Sumtsov, Georgyi Sumtsov, Nataliia Hyriavenko, Mykola Lyndin, Kateryna Sikora, Nataliia Kalashnik, Svitlana Smiian, Igor Gladchuk

Introduction: We reviewed 63 reports from the literature on rare non-serous tumors of the fallopian tubes and carried out a comparative analysis of clinical manifestations and diagnostic methods. We also report our observations from patients with these tumors.

Materials and methods: Of 157 patients with primary fallopian tube cancer (FTC) treated in our regional oncological hospital between 1970 and 2020, there were nine (6%) cases of rare non-serous cancers, including one case each of choriocarcinoma, carcinosarcoma, and neuroendocrine tumor, and two cases each of non-keratinizing squamous cell carcinoma, mucinous adenocarcinoma, and clear cell adenocarcinoma.

Results: For carcinosarcoma and squamous cell, clear cell, and transitional cell carcinomas, clinical history, patient age, and clinical manifestations were similar to the main group of FTCs. Choriocarcinoma differed significantly from other cancers of the fallopian tubes in terms of patient age and clinical course. Mucinous adenocarcinoma, mesothelioma, and borderline tumors, with rare exceptions, were almost always asymptomatic and were found only incidentally during surgery. Choriocarcinoma and carcinosarcoma had an aggressive course, while squamous cell, transitional cell, clear cell, and mucinous carcinomas were less aggressive. Since most rare non-serous tumors have a similar disease course to typical FTCs and there is a lack of appropriate treatment protocols for rare tumors, treatment options developed for ovarian tumors and FTC are justified for these tumors.

Conclusion: Rare non-serous malignant fallopian tube tumors are very similar to serous and endometrioid FTC in terms of clinical manifestations and diagnosis.

我们回顾了63例罕见的输卵管非浆液性肿瘤的文献报道,并对其临床表现和诊断方法进行了比较分析。我们也报道了我们对这些肿瘤患者的观察结果。材料与方法:1970年至2020年,本区肿瘤医院收治的157例原发性输卵管癌(FTC)患者中,罕见非浆液性肿瘤9例(6%),其中绒毛膜癌、癌肉瘤、神经内分泌肿瘤各1例,非角化鳞癌、粘液腺癌、透明细胞腺癌各2例。结果:癌肉瘤、鳞状细胞癌、透明细胞癌、移行细胞癌的临床病史、患者年龄、临床表现与FTCs主组相似。绒毛膜癌在患者年龄和临床病程方面与其他输卵管癌有显著差异。粘液腺癌、间皮瘤和交界性肿瘤,除少数例外,几乎总是无症状的,只是在手术中偶然发现的。绒毛膜癌和癌肉瘤具有侵袭性,而鳞状细胞癌、移行细胞癌、透明细胞癌和粘液癌的侵袭性较弱。由于大多数罕见的非浆液性肿瘤与典型的FTCs具有相似的病程,并且缺乏针对罕见肿瘤的适当治疗方案,因此针对卵巢肿瘤和FTC开发的治疗方案对于这些肿瘤是合理的。结论:罕见的非浆液性输卵管恶性肿瘤在临床表现和诊断上与浆液性和子宫内膜样FTC非常相似。
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引用次数: 0
Significance of plasma relaxin-2 levels in patients with primary hypertension and type 2 diabetes mellitus. 原发性高血压和 2 型糖尿病患者血浆松弛素-2 水平的意义。
IF 0.9 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-05-01 Epub Date: 2024-03-07 DOI: 10.1007/s10354-024-01035-x
Olena Pankova, Oleksii Korzh

Background: This study aimed to evaluate plasma relaxin‑2 (RLN-2) levels in patients with arterial hypertension (AH) and their relationships with clinical and laboratory parameters.

Methods: The study involved 106 hypertensive patients, including 55 with type 2 diabetes mellitus (T2DM), and 30 control subjects. Plasma RLN-2 levels were measured using an enzyme-linked immunosorbent assay kit.

Results: RLN-2 levels were reduced in patients with AH compared to healthy volunteers (p < 0.001), and hypertensive patients with T2DM had lower RLN-2 levels than those without impaired glucose metabolism (p < 0.001). RLN‑2 was negatively correlated with systolic blood pressure (SBP) (p < 0.001) and anthropometric parameters such as body mass index (BMI; p = 0.027), neck (p = 0.045) and waist (p = 0.003) circumferences, and waist-to-hip ratio (p = 0.011). RLN‑2 also had inverse associations with uric acid levels (p = 0.019) and lipid profile parameters, particularly triglycerides (p < 0.001) and non-HDL-C/HDL‑C (p < 0.001), and a positive relationship with HDL‑C (p < 0.001). RLN‑2 was negatively associated with glucose (p < 0.001), insulin (p = 0.043), HbA1c (p < 0.001), and HOMA-IR index (p < 0.001). Univariate binary logistic regression identified RLN‑2 as a significant predictor of impaired glucose metabolism (p < 0.001).

Conclusions: Decreased RLN-2 levels in patients with AH and T2DM and established relationships of RLN‑2 with SBP and parameters of glucose metabolism and lipid profile suggest a diagnostic role of RLN‑2 as a biomarker for AH with T2DM.

背景:本研究旨在评估动脉高血压(AH)患者血浆松弛素-2(RLN-2)水平及其与临床和实验室指标的关系:本研究旨在评估动脉高血压(AH)患者的血浆松弛素-2(RLN-2)水平及其与临床和实验室指标的关系:研究涉及 106 名高血压患者(包括 55 名 2 型糖尿病(T2DM)患者)和 30 名对照组受试者。使用酶联免疫吸附测定试剂盒测定血浆 RLN-2 水平:结果:与健康志愿者相比,AH 患者的 RLN-2 水平降低了(p 结论:AH 患者的 RLN-2 水平降低了:AH和T2DM患者的RLN-2水平降低,以及RLN-2与SBP、糖代谢参数和血脂谱的既定关系表明,RLN-2可作为AH和T2DM的生物标志物用于诊断。
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引用次数: 0
Influence of appropriate emergency department utilization and verbal communication on physicians' (dis)satisfaction with doctor-patient interactions with special consideration of migrational backgrounds. 适当使用急诊科和口头交流对医生医患互动(不)满意度的影响,特别考虑移民背景。
IF 0.9 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-05-01 Epub Date: 2022-07-18 DOI: 10.1007/s10354-022-00948-9
Anna Rahel Pötter, Odile Sauzet, Theda Borde, Baharan Naghavi, Oliver Razum, Jalid Sehouli, Rajan Somasundaram, Hendrike Stein, Matthias David

In recent years, utilization of emergency departments (EDs) has increased continuously, both in Germany and internationally. Inappropriate use of EDs is believed to be partly responsible for this trend. The topic of doctor-patient interaction (DPI) has received little attention in research. However, successful DPI is not only important for adherence and treatment success, but also for the satisfaction of medical staff. This non-interventionl cross-sectional study attempts to identify factors influencing physicians' satisfaction with DPIs, with a particular focus on the appropriate utilization of EDs and verbal communication. We carried out tripartite data collection in three EDs of major referral hospitals in Berlin between July 2017 and July 2018. Migration experience, communication and language problems, level of education, and a large gap between physicians' and patients' perceived urgency regarding the utilization of EDs influence the quality of the doctor-patient relationships and interactions.

近年来,急诊科(ED)的使用率在德国和国际上都持续上升。人们认为,急诊室的不当使用是造成这一趋势的部分原因。医患互动(DPI)这一主题在研究中很少受到关注。然而,成功的医患互动不仅对坚持治疗和治疗成功非常重要,而且对医务人员的满意度也非常重要。这项非干预性横断面研究试图找出影响医生对医患互动满意度的因素,尤其关注如何合理利用急诊室和语言沟通。2017 年 7 月至 2018 年 7 月期间,我们在柏林大型转诊医院的三个急诊室进行了三方数据收集。移民经验、沟通和语言问题、教育水平以及医生和患者对使用急诊室的紧迫感之间的巨大差距影响了医患关系和互动的质量。
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引用次数: 0
Preoperative anxiety after face-to-face patient assessment versus preanaesthesia telemedicine (PANTEM) in adults: a randomised clinical trial. 成人面对面患者评估后的术前焦虑与麻醉前远程医疗(PANTEM):一项随机临床试验
IF 0.9 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-05-01 Epub Date: 2022-05-30 DOI: 10.1007/s10354-022-00937-y
Georg Gibas, Martin Liebisch, Christiane Eichenberg, Vincent T Krenn, Aria Sallakhi, Salah E Benhebesse, Sibylle Kietaibl

Preanaesthesia consultation is performed to assess and optimise patient-specific risk factors before surgery, to inform patients about anaesthesia techniques and to obtain consent. Aside from face-to-face visits, telephone consultation is increasingly being used clinically. Concentration on the content and avoidance of confounding factors could lead to improved patient preparation. We hypothesised that patients receiving a telemedical intervention have less anxiety. Patients scheduled for elective surgery were randomised into two groups according to the consultation performed face-to-face (FTF) or via telephone (TEL). Before consultation (< 48 h) and 1-2 h prior to surgery, both groups had to fill in the State-Trait Anxiety Inventory (STAI). A total of 271 patients were randomised and 130 were analysed. There were no significant intergroup differences in mean state anxiety (STAI-S) before and after the intervention. Patients' positive feedback on telemedical consultation urges future studies on its effect on satisfaction and quality of life.

麻醉前咨询的目的是在手术前评估和优化患者的特定风险因素,向患者介绍麻醉技术并征得同意。除了面对面的咨询,电话咨询也越来越多地应用于临床。专注于咨询内容并避免混杂因素可改善患者的准备工作。我们假设,接受远程医疗干预的患者焦虑程度较低。根据面对面咨询(FTF)或电话咨询(TEL)的不同,计划接受择期手术的患者被随机分为两组。咨询前
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引用次数: 0
["He does not know it yet"-Triadic communication and its pitfalls exemplified by an oncological ward round consultation]. ["他还不知道"--以肿瘤科查房会诊为例说明三方沟通及其误区】。]
IF 0.9 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-05-01 Epub Date: 2022-04-06 DOI: 10.1007/s10354-022-00924-3
Bettina Baldt

Medical communication is an effective instrument for the medical practice. Due to the low status that medical communication still has within medicine and medical education, many physicians do not know how to use this instrument professionally. Using medical communication in a way that patients are well informed and involved is a prerequisite for them to make self-determined decisions. In this paper I analyze a consultation in an oncology ward to show the pitfalls of medical communication, especially in triadic communication, based on a case study to work out suggestions for optimization from the transcript. Mistakes in conducting conversations, which can be recognized as such in theory, unfortunately still happen in practice, which is why this case study is intended as an invitation to critically reflect on one's own conduct of conversations. The conclusion contains suggestions for the preparation as well as the conduct of the consultation during medical rounds.

医学交流是医疗实践的有效工具。由于医疗沟通在医学和医学教育中的地位仍然较低,许多医生不知道如何专业地使用这一工具。让患者充分了解和参与医疗沟通是他们做出自主决定的前提。在本文中,笔者分析了肿瘤科病房的一次会诊,以病例研究为基础,展示了医疗沟通的误区,尤其是三方沟通中的误区,并从记录中总结出优化建议。理论上可以认识到的会话中的错误,不幸的是在实践中仍然会发生,这就是为什么本案例研究旨在邀请人们对自己的会话行为进行批判性反思。结论中包含了对医疗查房中准备和进行会诊的建议。
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引用次数: 0
Hemispherotomy in an infant with hemimegalencephaly and Ohtahara syndrome. 半球切除术治疗患有巨脑症和大田原综合征的婴儿。
IF 0.9 Q2 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-04-01 Epub Date: 2023-04-18 DOI: 10.1007/s10354-023-01009-5
Katarina Pavičić Klancir, Dubravko Habek, Vlasta Đuranović, Ana Tripalo Batoš, Sanja Pejić Roško, Milan Stanojević

We represent the case of a premature twin neonate born from uncomplicated pregnancy who developed seizures at the age of 24 h. Two-dimensional ultrasound and magnetic resonance imaging revealed left-sided hemimegalencephaly. Further extensive diagnostic evaluation revealed a diagnosis of Ohtahara syndrome. Resistance of the seizures to antiepileptic therapy led to hemispherotomy that was performed at the age of 10 months. Our patient is now a 4-year-old child, walking, eating without a nasogastric tube, still with right hemiparesis and lateral strabismus but without seizures.

二维超声波和磁共振成像显示患儿左侧大脑半球畸形。进一步的广泛诊断评估显示其诊断为大田原综合征。由于癫痫发作对抗癫痫治疗产生抗药性,医生在患者10个月大时为其实施了半球切除术。患者现在已经 4 岁了,可以行走,不用鼻胃管进食,仍然患有右侧偏瘫和侧斜视,但没有癫痫发作。
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引用次数: 0
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Wiener medizinische Wochenschrift
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