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[Application of soft tissue balance combined with medial displacement calcaneal osteotomy for progressive collapsing foot deformity]. 【软组织平衡联合内侧移位跟骨截骨术在进行性塌陷足畸形中的应用】。
Q3 Medicine Pub Date : 2025-12-15 DOI: 10.7507/1002-1892.202509014
Guozhong Ye, Haiquan Mai, Liu Zhang, Boyuan Su, Guanglong Zeng, Haobo Huang

Objective: To explore the effectiveness of the flexor digitorum longus (FDL) transfer combined with single-bundle spring ligament reconstruction and medial displacement calcaneal osteotomy in the treatment of stage ⅠAB progressive collapsing foot deformity (PCFD).

Methods: Between January 2019 and September 2023, 19 patients (19 feet) with stage ⅠAB PCFD were treated with FDL transfer combined with single-bundle spring ligament reconstruction and medial displacement calcaneal osteotomy. There were 11 males and 8 females, aged 18 to 60 years, with an average age of 45.5 years. Nine cases were on the left foot and 10 cases on the right foot. The disease duration was 9-21 months, with an average of 12.3 months. Postoperatively, the effectiveness was evaluated by visual analogue scale (VAS) for pain, American Orthopaedic Foot and Ankle Society (AOFAS) score, and Tegner score. Based on X-ray films, the talonavicular coverage angle (TNCA), talus-first metatarsal angle (T1MT), Meary angle, and pitch angle were measured. The plantar pressure parameters of the foot were measured by the Footscan plantar pressure measurement system, including peak pressure and load of the forefoot, midfoot, and hind foot. The patients' satisfaction with the surgical outcome was evaluated.

Results: All 19 surgeries were successfully completed. One patient had poor incision healing after operation, while the incisions of the remaining patients healed by first intention. All patients were followed up 12-28 months (mean, 16.8 months). At last follow-up, the VAS score significantly decreased compared with that before operation, and the AOFAS score and Tegner score significantly increased ( P<0.05). Radiological measurements showed that the TNCA, T1MT, Meary angle, and Pitch angle all significantly improved compared with those before operation ( P<0.05). Plantar pressure tests indicated that the peak pressures of the forefoot and midfoot significantly reduced compared with those before operation ( P<0.05), while the peak pressure of the hind foot showed no significant change ( P>0.05). The forefoot load significantly increased and the midfoot load decreased compared with those before operation ( P<0.05), while the hind foot load showed no significant change ( P>0.05). The total satisfaction rate of patients with the surgical outcome (very satisfied+satisfied) reached 84.2% (16/19).

Conclusion: The FDL transfer combined with single-bundle spring ligament reconstruction and medial displacement calcaneal osteotomy can effectively correct the stage ⅠAB PCFD, improve the abnormal distribution of plantar pressure and load, alleviate foot pain symptoms, and improve foot movement function. The patient's satisfaction is high. However, the long-term effectiveness still needs to be further observed and clarified.

目的:探讨指长屈肌(FDL)转移联合单束弹簧韧带重建及内侧移位跟骨截骨术治疗ⅠAB期进行性塌陷足畸形(PCFD)的疗效。方法:2019年1月至2023年9月,对19例(19英尺)Ⅰ期AB型PCFD患者进行FDL转移联合单束弹簧韧带重建和内侧移位跟骨截骨治疗。男性11人,女性8人,年龄18 ~ 60岁,平均年龄45.5岁。左脚9例,右脚10例。病程9 ~ 21个月,平均12.3个月。术后采用疼痛视觉模拟评分(VAS)、美国骨科足踝学会(AOFAS)评分、Tegner评分评价疗效。根据x线片测量距骨覆盖角(TNCA)、距骨第一跖骨角(T1MT)、距骨角和俯仰角。采用Footscan足底压力测量系统测量足部压力参数,包括前足、中足和后足的峰值压力和负荷。评估患者对手术结果的满意度。结果:19例手术均顺利完成。1例患者术后切口愈合较差,其余患者切口一期愈合。所有患者随访12 ~ 28个月(平均16.8个月)。末次随访时,VAS评分较术前显著降低,AOFAS评分、Tegner评分显著升高(P0.05)。放射学测量显示,与术前相比,TNCA、T1MT、Meary角和Pitch角均有显著改善(PPP>0.05)。术前前足负荷显著增加,中足负荷显著降低(P < 0.05),后足负荷无显著变化(P < 0.05)。患者对手术结果的总满意率(非常满意+满意)为84.2%(16/19)。结论:FDL转移联合单束弹簧韧带重建+内侧移位跟骨截骨术可有效矫正ⅠAB期PCFD,改善足底压力负荷异常分布,缓解足部疼痛症状,改善足部运动功能。病人的满意度很高。但其长期效果仍需进一步观察和明确。
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引用次数: 0
[Research progress on augmentation repair of anterior talofibular ligament under arthroscopy]. [关节镜下距腓骨前韧带增强修复的研究进展]。
Q3 Medicine Pub Date : 2025-12-15 DOI: 10.7507/1002-1892.202508042
Minyuan Zhang, Kaiquan Li, Hongmai Yang, Yanlin Li

Objective: To summarize the research progress on augmentation repair of anterior talofibular ligament (ATFL) under arthroscopy.

Methods: The domestic and international studies from the past decade on augmentation repair techniques for the ATFL. The advantages and limitations of each approach were summarized and the outcomes of these augmentation repair techniques when applied to ATFL repair were evaluated.

Results: Mechanical augmentation technique (suture tape or internal brace technique, double anchor enhancement technique) can increase the strength after ATFL repair, but it will increase the economic burden of the patients; bioenhanced repair technology (inferior extensor retinaculum enhancement, anterior tibiofibular ligament's distal fascicle transfer augmentation) can also increase the strength after ATFL repair, but it will damage the anatomical structure in the ankle cavity to a certain extent, and the surgery is difficult, and the operation time will prolong and also increase the incidence of perioperative complications. Regardless of the augmentation repair techniques used, the benefits are higher for patients with high exercise needs, and active postoperative rehabilitation is required to maximize the surgical effect.

Conclusion: Although augmentation repair of ATFL offers several advantages, its use-whether augmentation should be employed and, if so, which technique is preferable-requires further study across patient subgroups owing to increased costs, potential disruption of ankle anatomy, and longer operation time.

目的:总结关节镜下距腓骨前韧带(ATFL)增强修复术的研究进展。方法:回顾近十年来国内外对ATFL增强修复技术的研究。总结了每种方法的优点和局限性,并评估了这些增强修复技术应用于ATFL修复时的结果。结果:机械增强技术(缝线带或内撑技术、双锚增强技术)可提高ATFL修复后的强度,但会增加患者的经济负担;生物增强修复技术(下伸肌视网膜带增强、胫腓前韧带远端束转移增强)也可以增加ATFL修复后的强度,但会在一定程度上损伤踝关节腔内的解剖结构,且手术难度大,手术时间延长,也增加了围手术期并发症的发生率。无论使用何种隆胸修复技术,对于高运动需求的患者,其益处更高,并且需要积极的术后康复以最大化手术效果。结论:尽管ATFL的增强修复有几个优点,但由于成本增加、踝关节解剖的潜在破坏和手术时间延长,其使用-是否应该使用增强修复,如果使用,哪种技术更可取-需要进一步研究患者亚组。
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引用次数: 0
[Key role of biomechanical properties and material selection in rotator cuff repair]. [生物力学性能和材料选择在肩袖修复中的关键作用]。
Q3 Medicine Pub Date : 2025-12-15 DOI: 10.7507/1002-1892.202506085
Xiangquan Cai, You Zhou

Objective: To summarize the biomechanical research progress of biomaterials in rotator cuff injury repair and to explore how biomaterials can restore the native histological and mechanical properties of the rotator cuff.

Methods: The relevant literature at home and abroad was widely reviewed to analyze the biomechanical properties of synthetic biomaterials, naturally derived biomaterials, and tissue grafts in the repair of rotator cuff injuries.

Results: Synthetic biomaterials [such as poly (lactic-co-glycolic acid) and polycaprolactone] can provide initial stable mechanical support due to their adjustable mechanical properties and degradation characteristics, while naturally derived biomaterials (such as collagen and hyaluronic acid) can promote cell adhesion and tissue integration due to their biocompatibility and bioactivity. Tissue grafts exhibit significant clinical utility by providing immediate mechanical stability and promoting tendon-to-bone healing. Three-dimensional bioprinting technology provides new possibilities for personalized repair of rotator cuff injuries by precisely controlling the spatial distribution and mechanical properties of biomaterials.

Conclusion: Future studies should further optimize the design of bioprinting materials, cell sources, and scaffolds to achieve better mechanical properties and clinical efficacy of biomaterials in the repair of rotator cuff injuries.

目的:总结生物材料在肩袖损伤修复中的生物力学研究进展,探讨生物材料如何恢复肩袖原有的组织学和力学性能。方法:广泛查阅国内外相关文献,分析合成生物材料、天然衍生生物材料和组织移植物在肩袖损伤修复中的生物力学性能。结果:人工合成的生物材料(如聚(乳酸-羟基乙酸)和聚己内酯)由于其可调节的力学性能和降解特性,可以提供初始稳定的机械支持,而天然来源的生物材料(如胶原蛋白和透明质酸)由于其生物相容性和生物活性,可以促进细胞粘附和组织整合。组织移植物通过提供即时的机械稳定性和促进肌腱到骨愈合而具有重要的临床应用价值。三维生物打印技术通过精确控制生物材料的空间分布和力学性能,为肩袖损伤的个性化修复提供了新的可能性。结论:未来的研究应进一步优化生物打印材料、细胞来源和支架的设计,使生物打印材料在肩袖损伤修复中获得更好的力学性能和临床疗效。
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引用次数: 0
[Effectiveness analysis of tibial nerve transection with epineurial suture and division of common plantar digital nerve branches in treatment of congenital macrodactyly in children]. 【神经外缝合胫神经横断加分足总指神经支治疗小儿先天性大指畸形的疗效分析】。
Q3 Medicine Pub Date : 2025-12-15 DOI: 10.7507/1002-1892.202510004
Dongmei Li, Guanglei Tian, Jianfeng Li, Min Zhao, Liang Zhao, Jingda Liu, Hailei Li
<p><strong>Objective: </strong>To evaluate the effectiveness of tibial nerve transection with epineurial suture and division of the common plantar digital nerve branches in the treatment of congenital macrodactyly in children.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on clinical data from 9 children with congenital macrodactyly who met the selection criteria and were admitted between January 2018 and December 2024. The cohort included 4 boys and 5 girls, aged 1-6 years (median, 3 years). Syndactyly of the second and third toes was present in 2 patients. Hypertrophy distribution was as follows: 1 case of single-ray involvement, 4 of double-ray, 1 of triple-ray, 1 of quadruple-ray, and 2 of quintuple-ray. Preoperatively, 7 cases exhibited limitations in both active and passive flexion and extension of the affected toes; in 2 cases, active movement was restricted while passive motion remained intact. All 9 children were unable to wear standard-sized footwear for the unaffected foot. Six presented with a limp, and 3 had difficulty walking. All 9 cases were moderate to severe progressive macrodactyly, and the growth rate of the affected foot was significantly faster than that of the healthy side. Six cases had undergone prior surgical interventions at other institutions, but disease progression continued postoperatively. All 9 patients underwent tibial nerve transection with epineurial suture and selective division of the common plantar digital nerve branches. At last follow-up, the foot growth rate was calculated (compared with that immediately after operation), and the changes of plantar pain sensation in the affected foot were detected before operation, immediately after operation, and at last follow-up, and the surgical efficacy was evaluated based on improvements in shoe fit and gait function.</p><p><strong>Results: </strong>All 9 children were followed up 6-36 months, with an average of 18 months. All the incisions healed by first intention, and no infection or plantar ulceration occurred. At last follow-up, the growth rate of the affected foot was 0.10 (0.04, 0.14) cm/month, which was significantly slower than that of the healthy foot [0.14 (0.08, 0.18) cm/month] ( <i>Z</i>=3.951, <i>P</i><0.001). Preoperatively, plantar pain sensation was absent in all cases; it was restored immediately after operation. At last follow-up, 6 patients had absent pain sensation, 2 had partial preservation (involving certain toes and central plantar regions), and 1 patient (with 3-year follow-up) exhibited regained sensation in multiple plantar areas. Gait improved in most cases, in which 8 children achieved normal ambulation, while 1 continued to limp due to leg-length discrepancy. Surgical efficacy were rated as excellent in 1 case, good in 7, and fair in 1.</p><p><strong>Conclusion: </strong>Tibial nerve transection with epineurial suture combined with selective division of the common plantar digital nerve branches effectively redu
目的:探讨神经外膜缝合胫神经横断及分离足底总指神经支治疗小儿先天性大指畸形的疗效。方法:回顾性分析2018年1月至2024年12月收治的9例符合入选标准的先天性大指畸形患儿的临床资料。该队列包括4名男孩和5名女孩,年龄1-6岁(中位数为3岁)。2例患者出现第二、三趾并指。肥大分布如下:单线受累1例,双线受累4例,三线受累1例,四线受累1例,五线受累2例。术前7例患趾主动和被动屈伸均受限;2例患者主动活动受限,而被动活动完好。所有9名儿童都无法为未受影响的脚穿标准尺寸的鞋子。6人跛行,3人行走困难。9例均为中重度进行性大指畸形,患足生长速度明显快于健侧。6例患者先前在其他机构接受过手术干预,但术后疾病继续进展。9例患者均行胫神经横断,神经外膜缝合,选择性分离足底总指神经支。最后随访时计算足部生长率(与术后即刻比较),检测患足术前、术后即刻及最后随访时足底疼痛感觉的变化,并根据鞋合度及步态功能的改善情况评价手术疗效。结果:9例患儿均随访6 ~ 36个月,平均18个月。所有切口一期愈合,无感染及足底溃疡发生。末次随访时,患足生长速度为0.10 (0.04,0.14)cm/月,明显慢于健足[0.14 (0.08,0.18)cm/月](Z=3.951, p)。神经外缝合胫神经横断联合选择性分割足底总指神经分支,有效降低儿童先天性大指畸形的生长速度,对足底感觉功能影响最小,不导致足底溃疡或行走障碍。
{"title":"[Effectiveness analysis of tibial nerve transection with epineurial suture and division of common plantar digital nerve branches in treatment of congenital macrodactyly in children].","authors":"Dongmei Li, Guanglei Tian, Jianfeng Li, Min Zhao, Liang Zhao, Jingda Liu, Hailei Li","doi":"10.7507/1002-1892.202510004","DOIUrl":"10.7507/1002-1892.202510004","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To evaluate the effectiveness of tibial nerve transection with epineurial suture and division of the common plantar digital nerve branches in the treatment of congenital macrodactyly in children.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A retrospective analysis was conducted on clinical data from 9 children with congenital macrodactyly who met the selection criteria and were admitted between January 2018 and December 2024. The cohort included 4 boys and 5 girls, aged 1-6 years (median, 3 years). Syndactyly of the second and third toes was present in 2 patients. Hypertrophy distribution was as follows: 1 case of single-ray involvement, 4 of double-ray, 1 of triple-ray, 1 of quadruple-ray, and 2 of quintuple-ray. Preoperatively, 7 cases exhibited limitations in both active and passive flexion and extension of the affected toes; in 2 cases, active movement was restricted while passive motion remained intact. All 9 children were unable to wear standard-sized footwear for the unaffected foot. Six presented with a limp, and 3 had difficulty walking. All 9 cases were moderate to severe progressive macrodactyly, and the growth rate of the affected foot was significantly faster than that of the healthy side. Six cases had undergone prior surgical interventions at other institutions, but disease progression continued postoperatively. All 9 patients underwent tibial nerve transection with epineurial suture and selective division of the common plantar digital nerve branches. At last follow-up, the foot growth rate was calculated (compared with that immediately after operation), and the changes of plantar pain sensation in the affected foot were detected before operation, immediately after operation, and at last follow-up, and the surgical efficacy was evaluated based on improvements in shoe fit and gait function.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;All 9 children were followed up 6-36 months, with an average of 18 months. All the incisions healed by first intention, and no infection or plantar ulceration occurred. At last follow-up, the growth rate of the affected foot was 0.10 (0.04, 0.14) cm/month, which was significantly slower than that of the healthy foot [0.14 (0.08, 0.18) cm/month] ( &lt;i&gt;Z&lt;/i&gt;=3.951, &lt;i&gt;P&lt;/i&gt;&lt;0.001). Preoperatively, plantar pain sensation was absent in all cases; it was restored immediately after operation. At last follow-up, 6 patients had absent pain sensation, 2 had partial preservation (involving certain toes and central plantar regions), and 1 patient (with 3-year follow-up) exhibited regained sensation in multiple plantar areas. Gait improved in most cases, in which 8 children achieved normal ambulation, while 1 continued to limp due to leg-length discrepancy. Surgical efficacy were rated as excellent in 1 case, good in 7, and fair in 1.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Tibial nerve transection with epineurial suture combined with selective division of the common plantar digital nerve branches effectively redu","PeriodicalId":23979,"journal":{"name":"中国修复重建外科杂志","volume":"39 12","pages":"1562-1567"},"PeriodicalIF":0.0,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12705307/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145763942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Early follow-up study on three-dimensional-printed customized porous acetabular components for reconstructing extensive acetabular bone defects in primary total hip arthroplasty]. 【首次全髋关节置换术中三维打印定制多孔髋臼构件重建大面积髋臼骨缺损的早期随访研究】。
Q3 Medicine Pub Date : 2025-12-15 DOI: 10.7507/1002-1892.202508045
Shangkun Tang, Zhuangzhuang Li, Xin Hu, Linyun Tan, Hao Wang, Yitian Wang, Minxun Lu, Fan Tang, Yi Luo, Yong Zhou, Chongqi Tu, Li Min

Objective: To evaluate the feasibility and short-term effectiveness of three-dimensional (3D)-printed customized porous acetabular components for reconstruction of extensive acetabular bone defects during primary total hip arthroplasty (THA).

Methods: The clinical data of 8 patients with extensive acetabular bone defects, who were treated with 3D-printed individualized porous acetabular components between July 2018 and January 2022, were retrospectively analyzed. The cohort comprised 4 males and 4 females with an average age of 48 years ranging from 34 to 56 years. Acetabular bone defects were classified as Paprosky type ⅢA in 3 cases and type ⅢB in 5 cases. The causes of acetabular destruction were hip tuberculosis (5 cases), pigmented villonodular synovitis (2 cases), and syphilitic arthritis (1 case). Visual analogue scale (VAS) score and Harris hip score (HHS) were used to evaluate the pain relief and hip function before and after operation. Reconstruction outcomes were further assessed by imaging results [X-ray film and Tomosynthesis Shimadzumetal artefact reduction technology (T-SMART)], and the mechanical properties were evaluated by finite element analysis.

Results: The operation time ranged from 174 to 195 minutes (mean, 187 minutes), and intraoperative blood loss ranged from 390 to 530 mL (mean, 465 mL). All 8 patients were follow-up 26-74 months (mean, 44 months). Among the 5 patients with tuberculosis, none experienced postoperative recurrence. At last follow-up, the VAS score was 0.3±0.5 and the HHS score was 87.9±3.7, both significantly improved compared to preoperative values ( t=25.170, P<0.001; t=-28.322, P<0.001). X-ray films at 2 years after operation demonstrated satisfactory matching between the 3D-printed customized acetabular component and the acetabulum. The postoperative center of rotation of the operated hip was shifted by (2.1±0.5) mm horizontally and (2.0±0.7) mm vertically relative to the contralateral side, with both offsets showing significant differences compared to preoperative values ( t=24.700, P<0.001; t=55.230, P<0.001). T-SMART imaging showed satisfactory osseointegration at the implant-host bone interface. No complications such as aseptic loosening or screw breakage was observed during follow-up. Finite element analysis showed that the acetabular component had good mechanical properties.

Conclusion: The application of 3D-printed individualized porous acetabular components in the reconstruction of extensive acetabular bone defects demonstrated precise anatomical reconstruction, stable mechanical support, and good functional performance in short-term follow-up, offering a potential alternative for acetabular defect reconstruction in primary THA.

目的:评价三维(3D)打印定制多孔髋臼假体在初次全髋关节置换术(THA)中广泛髋臼骨缺损重建中的可行性和短期效果。方法:回顾性分析2018年7月至2022年1月8例采用3d打印个体化多孔髋臼假体治疗大面积髋臼骨缺损患者的临床资料。该队列包括4男4女,平均年龄48岁,年龄从34岁到56岁不等。髋臼骨缺损3例为papprosky型ⅢA型,5例为ⅢB型。髋臼破坏原因为髋部结核(5例)、色素绒毛结节性滑膜炎(2例)、梅毒性关节炎(1例)。采用视觉模拟评分法(VAS)和Harris髋关节评分法(HHS)评价手术前后患者的疼痛缓解程度和髋关节功能。通过成像结果[x射线胶片和Tomosynthesis Shimadzumetal伪影还原技术(T-SMART)]进一步评估重建结果,并通过有限元分析评估力学性能。结果:手术时间174 ~ 195 min(平均187 min),术中出血量390 ~ 530 mL(平均465 mL)。8例患者均随访26 ~ 74个月(平均44个月)。5例结核患者术后无复发。末次随访时,VAS评分为0.3±0.5分,HHS评分为87.9±3.7分,均较术前显著改善(t=25.170, Pt=-28.322, Pt=24.700, Pt=55.230, p)。3d打印个体化多孔髋臼构件在广泛髋臼骨缺损重建中的应用,在短期随访中表现出解剖重建精确、机械支撑稳定、功能表现良好的特点,为原发性THA髋臼缺损重建提供了一种潜在的替代方案。
{"title":"[Early follow-up study on three-dimensional-printed customized porous acetabular components for reconstructing extensive acetabular bone defects in primary total hip arthroplasty].","authors":"Shangkun Tang, Zhuangzhuang Li, Xin Hu, Linyun Tan, Hao Wang, Yitian Wang, Minxun Lu, Fan Tang, Yi Luo, Yong Zhou, Chongqi Tu, Li Min","doi":"10.7507/1002-1892.202508045","DOIUrl":"10.7507/1002-1892.202508045","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the feasibility and short-term effectiveness of three-dimensional (3D)-printed customized porous acetabular components for reconstruction of extensive acetabular bone defects during primary total hip arthroplasty (THA).</p><p><strong>Methods: </strong>The clinical data of 8 patients with extensive acetabular bone defects, who were treated with 3D-printed individualized porous acetabular components between July 2018 and January 2022, were retrospectively analyzed. The cohort comprised 4 males and 4 females with an average age of 48 years ranging from 34 to 56 years. Acetabular bone defects were classified as Paprosky type ⅢA in 3 cases and type ⅢB in 5 cases. The causes of acetabular destruction were hip tuberculosis (5 cases), pigmented villonodular synovitis (2 cases), and syphilitic arthritis (1 case). Visual analogue scale (VAS) score and Harris hip score (HHS) were used to evaluate the pain relief and hip function before and after operation. Reconstruction outcomes were further assessed by imaging results [X-ray film and Tomosynthesis Shimadzumetal artefact reduction technology (T-SMART)], and the mechanical properties were evaluated by finite element analysis.</p><p><strong>Results: </strong>The operation time ranged from 174 to 195 minutes (mean, 187 minutes), and intraoperative blood loss ranged from 390 to 530 mL (mean, 465 mL). All 8 patients were follow-up 26-74 months (mean, 44 months). Among the 5 patients with tuberculosis, none experienced postoperative recurrence. At last follow-up, the VAS score was 0.3±0.5 and the HHS score was 87.9±3.7, both significantly improved compared to preoperative values ( <i>t</i>=25.170, <i>P</i><0.001; <i>t</i>=-28.322, <i>P</i><0.001). X-ray films at 2 years after operation demonstrated satisfactory matching between the 3D-printed customized acetabular component and the acetabulum. The postoperative center of rotation of the operated hip was shifted by (2.1±0.5) mm horizontally and (2.0±0.7) mm vertically relative to the contralateral side, with both offsets showing significant differences compared to preoperative values ( <i>t</i>=24.700, <i>P</i><0.001; <i>t</i>=55.230, <i>P</i><0.001). T-SMART imaging showed satisfactory osseointegration at the implant-host bone interface. No complications such as aseptic loosening or screw breakage was observed during follow-up. Finite element analysis showed that the acetabular component had good mechanical properties.</p><p><strong>Conclusion: </strong>The application of 3D-printed individualized porous acetabular components in the reconstruction of extensive acetabular bone defects demonstrated precise anatomical reconstruction, stable mechanical support, and good functional performance in short-term follow-up, offering a potential alternative for acetabular defect reconstruction in primary THA.</p>","PeriodicalId":23979,"journal":{"name":"中国修复重建外科杂志","volume":"39 12","pages":"1543-1550"},"PeriodicalIF":0.0,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12705331/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145763980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effectiveness of arthroscopic treatment for femoroacetabular impingement syndrome combined with ligamentum teres injury]. [关节镜治疗股髋臼撞击综合征合并圆韧带损伤的疗效]。
Q3 Medicine Pub Date : 2025-12-15 DOI: 10.7507/1002-1892.202508055
Siyu Han, Song Li, Di Jia, Yanlin Li, Guofeng Cai

Objective: To investigate the effectiveness of hip arthroscopy in the treatment of patients with femoroacetabular impingement (FAI) syndrome combined with ligamentum teres injury.

Methods: A retrospective analysis was conducted on 23 patients (23 hips) with Cam-type FAI syndrome combined with ligamentum teres injury who met the selection criteria between April 2022 and May 2024. The cohort included 12 males and 11 females, with a mean age of 29.16 years (range, 16-57 years). According to Tönnis classification, there were 5 cases of grade 0, 10 cases of grade Ⅰ, and 8 cases of grade Ⅱ in hip osteoarthritis. The disease duration ranged from 6 to 24 months, with an average of 12 months. Under hip arthroscopy, hypertrophic synovium and the damaged ligamentum teres were debrided, while the torn labrum and cartilage were repaired, and femoral head-neck osteoplasty was performed to eliminate impingement, restore the normal morphology of the acetabulum and femoral head-neck, and suture the joint capsule. Acetabular lateral center-edge angle (LCEA) and α angle (reflecting the degree of non-sphericity at the femoral head-neck junction) were measured before and after operation, and the modified Harris hip score (mHHS), the International Hip Outcome Tool-12 (IHOT-12), and the visual analogue scale (VAS) score for pain were evaluated.

Results: The operation was successfully completed in all patients. The incisions healed by first intention after operation, and there was no perioperative complications such as iatrogenic cartilage injury, fracture, infection, neurovascular traction injury, or lower extremity venous thrombosis. All the 23 patients were followed up 12-24 months, with an average of 14.6 months. The pain of hip joint significantly relieved, and the function of hip joint improved; no complication such as joint stiffness, joint instability, and osteonecrosis of the femoral head occurred. The α angle, VAS score, mHHS score, and IHOT-12 score at last follow-up were significantly better than those before operation ( P<0.05); there was no significant difference in LCEA compared to preoperative value ( P>0.05).

Conclusion: Hip arthroscopy is a safe and effective treatment for patients with FAI syndrome combined with ligamentum teres injury, which can achieve satisfactory effectiveness.

目的:探讨髋关节镜治疗股髋臼撞击(FAI)综合征合并圆韧带损伤的疗效。方法:对2022年4月至2024年5月符合入选标准的23例(23髋)cam型FAI综合征合并圆韧带损伤患者进行回顾性分析。该队列包括12名男性,11名女性,平均年龄29.16岁(范围16-57岁)。根据Tönnis分级,0级5例,Ⅰ级10例,Ⅱ级8例。病程6 ~ 24个月,平均12个月。在髋关节镜下,对肥厚的滑膜及受损的圆韧带进行清创,对撕裂的唇、软骨进行修复,并行股骨头颈成形术消除撞击,恢复髋臼及股骨头颈的正常形态,并缝合关节囊。术前、术后测量髋臼外侧中缘角(LCEA)和α角(反映股骨头颈交界处非球形程度),评估改良Harris髋关节评分(mHHS)、国际髋关节预后工具-12 (IHOT-12)、疼痛视觉模拟评分(VAS)。结果:所有患者均顺利完成手术。术后切口一期愈合,围手术期无医源性软骨损伤、骨折、感染、神经血管牵拉损伤、下肢静脉血栓形成等并发症。23例患者均随访12 ~ 24个月,平均14.6个月。髋关节疼痛明显减轻,髋关节功能改善;无关节僵硬、关节不稳定、股骨头坏死等并发症发生。末次随访时患者的α角、VAS评分、mHHS评分、IHOT-12评分均显著优于术前(p < 0.05)。结论:髋关节镜治疗FAI综合征合并圆韧带损伤是一种安全有效的治疗方法,可取得满意的疗效。
{"title":"[Effectiveness of arthroscopic treatment for femoroacetabular impingement syndrome combined with ligamentum teres injury].","authors":"Siyu Han, Song Li, Di Jia, Yanlin Li, Guofeng Cai","doi":"10.7507/1002-1892.202508055","DOIUrl":"10.7507/1002-1892.202508055","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the effectiveness of hip arthroscopy in the treatment of patients with femoroacetabular impingement (FAI) syndrome combined with ligamentum teres injury.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 23 patients (23 hips) with Cam-type FAI syndrome combined with ligamentum teres injury who met the selection criteria between April 2022 and May 2024. The cohort included 12 males and 11 females, with a mean age of 29.16 years (range, 16-57 years). According to Tönnis classification, there were 5 cases of grade 0, 10 cases of grade Ⅰ, and 8 cases of grade Ⅱ in hip osteoarthritis. The disease duration ranged from 6 to 24 months, with an average of 12 months. Under hip arthroscopy, hypertrophic synovium and the damaged ligamentum teres were debrided, while the torn labrum and cartilage were repaired, and femoral head-neck osteoplasty was performed to eliminate impingement, restore the normal morphology of the acetabulum and femoral head-neck, and suture the joint capsule. Acetabular lateral center-edge angle (LCEA) and α angle (reflecting the degree of non-sphericity at the femoral head-neck junction) were measured before and after operation, and the modified Harris hip score (mHHS), the International Hip Outcome Tool-12 (IHOT-12), and the visual analogue scale (VAS) score for pain were evaluated.</p><p><strong>Results: </strong>The operation was successfully completed in all patients. The incisions healed by first intention after operation, and there was no perioperative complications such as iatrogenic cartilage injury, fracture, infection, neurovascular traction injury, or lower extremity venous thrombosis. All the 23 patients were followed up 12-24 months, with an average of 14.6 months. The pain of hip joint significantly relieved, and the function of hip joint improved; no complication such as joint stiffness, joint instability, and osteonecrosis of the femoral head occurred. The α angle, VAS score, mHHS score, and IHOT-12 score at last follow-up were significantly better than those before operation ( <i>P</i><0.05); there was no significant difference in LCEA compared to preoperative value ( <i>P</i>>0.05).</p><p><strong>Conclusion: </strong>Hip arthroscopy is a safe and effective treatment for patients with FAI syndrome combined with ligamentum teres injury, which can achieve satisfactory effectiveness.</p>","PeriodicalId":23979,"journal":{"name":"中国修复重建外科杂志","volume":"39 12","pages":"1551-1555"},"PeriodicalIF":0.0,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12705311/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145764015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Eccentric kyphotic distraction reduction technique for treatment of lower cervical dislocation with locked facet joints]. [偏心后凸撑开复位技术治疗下颈脱位伴小关节锁定]。
Q3 Medicine Pub Date : 2025-12-15 DOI: 10.7507/1002-1892.202509052
Yuwei Li, Xiuzhi Li, Bowen Li, Xiaoyun Yan, Ruijuan Ding, Wei Cui, Haijiao Wang

Objective: To evaluate the effectiveness of the single-stage anterior eccentric kyphotic distraction reduction technique (EKD-RT) for treating lower cervical dislocation with locked facet joints, assessing its reduction success rate, neurological improvement, and safety.

Methods: A retrospective analysis was conducted on 67 patients with lower cervical dislocation and locked facet joints (21 unilateral, 46 bilateral) treated between January 2015 and January 2024. There were 39 males and 28 females, with an average age of 49.5 years (range, 22-75 years). The injured segments included C 3, 4 in 4 cases, C 4, 5 in 13 cases, C 5, 6 in 22 cases, and C 6, 7 in 28 cases. The interval between injury and admission ranged from 2 hours to 2 days (mean, 5.6 hours). Preoperative Frankel grading included grade A in 9 cases, grade B in 28 cases, grade C in 17 cases, grade D in 11 cases, and grade E in 2 cases. Japanese Orthopaedic Association (JOA) score was 7.0±1.4. All patients underwent single-stage anterior cervical discectomy and fusion. Following discectomy at the dislocated level, the EKD-RT was applied to unlock and reduce the locked facet joints, followed by internal fixation. Operation time, blood loss, reduction success rate, and complications were recorded. Interbody fusion status was evaluated using Bridwell criteria. Neurological status was assessed pre- and post-operatively using Frankel grading. Spinal cord function was scored using the 17-point JOA score, and the improvement rate was calculated.

Results: Successful reduction of the locked facet joints achieved in all cases. The operation time was 41-85 minutes (range, 63.3 minutes), and intraoperative blood loss was 50-360 mL (range, 125.0 mL). Complications included cerebrospinal fluid leakage in 2 cases; no severe complications such as major vascular injury or recurrent laryngeal nerve injury occurred. All patients were followed up 12-24 months (mean, 17.9 months). At last follow-up, radiological examination confirmed interbody fusion in all patients, with no implant failure or migration. The Frankel grading included grade A in 3 cases, grade B in 9 cases, grade C in 13 cases, grade D in 16 cases, and grade E in 26 cases; the JOA score reached 13.7±2.3; all of which significantly improved compared to preoperative levels ( P<0.05). The improvement rate of JOA score was 66.1%±24.7%.

Conclusion: The EKD-RT is an effective surgical approach for lower cervical dislocation with locked facet joints. It enables safe and efficient reduction of the locked facet joints via a single incision, resulting in significant neurological improvement with a low complication rate.

目的:评价单期前偏心后凸牵张复位技术(EKD-RT)治疗下颈脱位伴小关节锁定的有效性,评估其复位成功率、神经系统改善情况及安全性。方法:回顾性分析2015年1月至2024年1月间治疗的67例下颈椎脱位伴小关节锁定患者(单侧21例,双侧46例)。男性39例,女性28例,平均年龄49.5岁(22 ~ 75岁)。损伤节段包括c3,4 4例,c4,5 13例,c5,6 22例,c6,7 28例。从受伤到入院的时间间隔为2小时至2天(平均5.6小时)。术前Frankel分级为A级9例,B级28例,C级17例,D级11例,E级2例。日本骨科协会(JOA)评分为7.0±1.4分。所有患者均行单期颈椎前路椎间盘切除术和融合术。在脱位节段椎间盘切除术后,应用EKD-RT解锁和复位锁定的关节突关节,然后进行内固定。记录手术时间、出血量、复位成功率及并发症。采用Bridwell标准评估椎间融合状态。术前和术后采用Frankel分级法评估神经系统状态。采用17分JOA评分对脊髓功能进行评分,并计算改善率。结果:所有病例均成功复位锁定小关节。手术时间41 ~ 85分钟(范围63.3分钟),术中出血量50 ~ 360 mL(范围125.0 mL)。并发症包括脑脊液漏2例;无大血管损伤、喉返神经损伤等严重并发症。随访12 ~ 24个月,平均17.9个月。最后随访,放射学检查证实所有患者体间融合,无植入物失败或移位。Frankel分级为A级3例,B级9例,C级13例,D级16例,E级26例;JOA评分为13.7±2.3分;结论:EKD-RT是治疗下颈脱位伴小关节锁定的有效手术入路。它可以通过单个切口安全有效地复位锁定的小关节,显著改善神经系统,并发症发生率低。
{"title":"[Eccentric kyphotic distraction reduction technique for treatment of lower cervical dislocation with locked facet joints].","authors":"Yuwei Li, Xiuzhi Li, Bowen Li, Xiaoyun Yan, Ruijuan Ding, Wei Cui, Haijiao Wang","doi":"10.7507/1002-1892.202509052","DOIUrl":"10.7507/1002-1892.202509052","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the effectiveness of the single-stage anterior eccentric kyphotic distraction reduction technique (EKD-RT) for treating lower cervical dislocation with locked facet joints, assessing its reduction success rate, neurological improvement, and safety.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 67 patients with lower cervical dislocation and locked facet joints (21 unilateral, 46 bilateral) treated between January 2015 and January 2024. There were 39 males and 28 females, with an average age of 49.5 years (range, 22-75 years). The injured segments included C <sub>3, 4</sub> in 4 cases, C <sub>4, 5</sub> in 13 cases, C <sub>5, 6</sub> in 22 cases, and C <sub>6, 7</sub> in 28 cases. The interval between injury and admission ranged from 2 hours to 2 days (mean, 5.6 hours). Preoperative Frankel grading included grade A in 9 cases, grade B in 28 cases, grade C in 17 cases, grade D in 11 cases, and grade E in 2 cases. Japanese Orthopaedic Association (JOA) score was 7.0±1.4. All patients underwent single-stage anterior cervical discectomy and fusion. Following discectomy at the dislocated level, the EKD-RT was applied to unlock and reduce the locked facet joints, followed by internal fixation. Operation time, blood loss, reduction success rate, and complications were recorded. Interbody fusion status was evaluated using Bridwell criteria. Neurological status was assessed pre- and post-operatively using Frankel grading. Spinal cord function was scored using the 17-point JOA score, and the improvement rate was calculated.</p><p><strong>Results: </strong>Successful reduction of the locked facet joints achieved in all cases. The operation time was 41-85 minutes (range, 63.3 minutes), and intraoperative blood loss was 50-360 mL (range, 125.0 mL). Complications included cerebrospinal fluid leakage in 2 cases; no severe complications such as major vascular injury or recurrent laryngeal nerve injury occurred. All patients were followed up 12-24 months (mean, 17.9 months). At last follow-up, radiological examination confirmed interbody fusion in all patients, with no implant failure or migration. The Frankel grading included grade A in 3 cases, grade B in 9 cases, grade C in 13 cases, grade D in 16 cases, and grade E in 26 cases; the JOA score reached 13.7±2.3; all of which significantly improved compared to preoperative levels ( <i>P</i><0.05). The improvement rate of JOA score was 66.1%±24.7%.</p><p><strong>Conclusion: </strong>The EKD-RT is an effective surgical approach for lower cervical dislocation with locked facet joints. It enables safe and efficient reduction of the locked facet joints via a single incision, resulting in significant neurological improvement with a low complication rate.</p>","PeriodicalId":23979,"journal":{"name":"中国修复重建外科杂志","volume":"39 12","pages":"1568-1573"},"PeriodicalIF":0.0,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12705330/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145763983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Endoscopic-assisted median nerve decompression combined with one-stage tendon transfer for reconstruction of thumb abduction in treatment of severe carpal tunnel syndrome]. [内窥镜辅助正中神经减压联合一期肌腱转移重建拇外展治疗严重腕管综合征]。
Q3 Medicine Pub Date : 2025-12-15 DOI: 10.7507/1002-1892.202508049
Jiaxing Sui, Yong Yang, Zhenzhong Wang, Xingjian Huang, Xuanyu Jiang, Lihui Zhang, Haiyang Li

Objective: To investigate the effectiveness of endoscopic-assisted median nerve decompression with one-stage extensor indicis proprius (EIP) tendon transfer for reconstruction of thumb abduction in patients with severe carpal tunnel syndrome (CTS).

Methods: The clinical data of 12 patients with severe CTS who met the selection criteria between December 2019 and December 2024 were retrospectively analyzed. There were 2 males and 10 females with an average age of 55.4 years ranging from 35 to 67 years. The symptom duration of CTS was 12-120 months (mean, 48.7 months) and the thenar muscle atrophy duration was 6-48 months (mean, 13.4 months). The median nerve was released with the help of endoscope, and the EIP tendon was transferred to reconstruct the abduction function of the thumb. The operation time and complications were recorded. Two-point discrimination, palmar abduction angle of the thumb, radial abduction angle of the thumb, and pinch force of the thumb were measured and compared before operation and at last follow-up, and the effectiveness was evaluated by Kapandji score and Disabilities of the Arm, Shoulder and Hand (DASH) score. The satisfaction of the operation was evaluated at last follow-up.

Results: All surgeries were successfully completed with a mean operation time of 54 minutes (range, 45-68 minutes). All patients were followed up 6-50 months, with an average of 15.3 months. There was no complications such as wound infection, scar pain of wrist, or tendon rupture of transposition, and there were 3 cases of mild limitation of finger extension in the donor site of index finger. At last follow-up, two-point discrimination, palmar abduction angle of the thumb, radial abduction angle of the thumb, Kapandji score, and DASH score were significantly better than those before operation ( P<0.05), but there was no significant difference in thumb pinch force between pre- and post-operation ( P>0.05). The evaluation of surgical satisfaction showed that 7 cases were very satisfied and 5 cases were satisfied.

Conclusion: The combination of endoscopic-assisted median nerve decompression and one-stage EIP tendon transfer effectively improves hand function and quality of life in patients with severe CTS by restoring thumb abduction and alleviating neurological symptoms.

目的:探讨内窥镜辅助下一期指固有伸肌(EIP)正中神经减压术在重度腕管综合征(CTS)患者拇指外展重建中的疗效。方法:回顾性分析2019年12月至2024年12月符合入选标准的12例重度CTS患者的临床资料。男性2名,女性10名,平均年龄55.4岁,年龄在35岁至67岁之间。CTS症状持续时间12 ~ 120个月(平均48.7个月),大鱼际肌萎缩持续时间6 ~ 48个月(平均13.4个月)。在内窥镜的帮助下释放正中神经,转移EIP肌腱重建拇指外展功能。记录手术时间及并发症。术前及随访时分别测量两点辨别、拇指掌外展角、拇指桡外展角、拇指捏捏力,并采用Kapandji评分和臂肩手残疾(DASH)评分评价疗效。最后随访评价手术满意度。结果:所有手术均顺利完成,平均手术时间54分钟(范围45 ~ 68分钟)。随访6 ~ 50个月,平均15.3个月。无创面感染、腕部瘢痕痛、转位肌腱断裂等并发症,有3例食指供区手指伸展轻度受限。最后随访时,两点辨别力、拇指掌外展角、拇指桡外展角、Kapandji评分、DASH评分均显著优于术前(p < 0.05)。手术满意度评价:非常满意7例,满意5例。结论:内窥镜辅助正中神经减压联合一期EIP肌腱移植可恢复拇外展,减轻神经系统症状,有效改善重度CTS患者的手部功能和生活质量。
{"title":"[Endoscopic-assisted median nerve decompression combined with one-stage tendon transfer for reconstruction of thumb abduction in treatment of severe carpal tunnel syndrome].","authors":"Jiaxing Sui, Yong Yang, Zhenzhong Wang, Xingjian Huang, Xuanyu Jiang, Lihui Zhang, Haiyang Li","doi":"10.7507/1002-1892.202508049","DOIUrl":"10.7507/1002-1892.202508049","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the effectiveness of endoscopic-assisted median nerve decompression with one-stage extensor indicis proprius (EIP) tendon transfer for reconstruction of thumb abduction in patients with severe carpal tunnel syndrome (CTS).</p><p><strong>Methods: </strong>The clinical data of 12 patients with severe CTS who met the selection criteria between December 2019 and December 2024 were retrospectively analyzed. There were 2 males and 10 females with an average age of 55.4 years ranging from 35 to 67 years. The symptom duration of CTS was 12-120 months (mean, 48.7 months) and the thenar muscle atrophy duration was 6-48 months (mean, 13.4 months). The median nerve was released with the help of endoscope, and the EIP tendon was transferred to reconstruct the abduction function of the thumb. The operation time and complications were recorded. Two-point discrimination, palmar abduction angle of the thumb, radial abduction angle of the thumb, and pinch force of the thumb were measured and compared before operation and at last follow-up, and the effectiveness was evaluated by Kapandji score and Disabilities of the Arm, Shoulder and Hand (DASH) score. The satisfaction of the operation was evaluated at last follow-up.</p><p><strong>Results: </strong>All surgeries were successfully completed with a mean operation time of 54 minutes (range, 45-68 minutes). All patients were followed up 6-50 months, with an average of 15.3 months. There was no complications such as wound infection, scar pain of wrist, or tendon rupture of transposition, and there were 3 cases of mild limitation of finger extension in the donor site of index finger. At last follow-up, two-point discrimination, palmar abduction angle of the thumb, radial abduction angle of the thumb, Kapandji score, and DASH score were significantly better than those before operation ( <i>P</i><0.05), but there was no significant difference in thumb pinch force between pre- and post-operation ( <i>P</i>>0.05). The evaluation of surgical satisfaction showed that 7 cases were very satisfied and 5 cases were satisfied.</p><p><strong>Conclusion: </strong>The combination of endoscopic-assisted median nerve decompression and one-stage EIP tendon transfer effectively improves hand function and quality of life in patients with severe CTS by restoring thumb abduction and alleviating neurological symptoms.</p>","PeriodicalId":23979,"journal":{"name":"中国修复重建外科杂志","volume":"39 12","pages":"1510-1515"},"PeriodicalIF":0.0,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12705314/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145763935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Application and advances of exosome-hydrogel system in wound healing]. 外泌体-水凝胶体系在伤口愈合中的应用与进展
Q3 Medicine Pub Date : 2025-12-15 DOI: 10.7507/1002-1892.202506093
Yan Qiu, Qian Tan

Objective: To review the recent advances in the application of exosome-hydrogel system for wound healing.

Methods: A wide range of recent domestic and international studies were reviewed to systematically outline the roles and mechanisms of exosomes, hydrogels, and their composite system in promoting wound repair.

Results: Wound healing is a complex and finely regulated process. Traditional therapies lack targeted regulation of key mechanisms such as inflammation control, angiogenesis, collagen remodeling, and re-epithelialization. The exosome-hydrogel system enhances wound repair through targeted modulation of these mechanisms and provides effective protection against bacterial infection, hypoxia, excessive oxidative stress, and hyperglycemic microenvironments.

Conclusion: The exosome-hydrogel system represents an emerging approach for chronic wound repair and skin regeneration, potentially overcoming the inherent limitations of traditional therapies. Nevertheless, the lack of standardized preparation methods and dosing protocols calls for further optimization.

目的:综述外泌体-水凝胶体系在伤口愈合中的应用进展。方法:对近年来国内外广泛的研究进行综述,系统概述外泌体、水凝胶及其复合体系在促进创面修复中的作用和机制。结果:伤口愈合是一个复杂而精细的过程。传统疗法缺乏对炎症控制、血管生成、胶原重塑和再上皮化等关键机制的靶向调节。外泌体-水凝胶系统通过靶向调节这些机制来增强伤口修复,并提供有效的保护,防止细菌感染、缺氧、过度氧化应激和高血糖微环境。结论:外泌体-水凝胶系统代表了慢性伤口修复和皮肤再生的一种新兴方法,有可能克服传统疗法的固有局限性。然而,由于缺乏标准化的制备方法和给药方案,需要进一步优化。
{"title":"[Application and advances of exosome-hydrogel system in wound healing].","authors":"Yan Qiu, Qian Tan","doi":"10.7507/1002-1892.202506093","DOIUrl":"10.7507/1002-1892.202506093","url":null,"abstract":"<p><strong>Objective: </strong>To review the recent advances in the application of exosome-hydrogel system for wound healing.</p><p><strong>Methods: </strong>A wide range of recent domestic and international studies were reviewed to systematically outline the roles and mechanisms of exosomes, hydrogels, and their composite system in promoting wound repair.</p><p><strong>Results: </strong>Wound healing is a complex and finely regulated process. Traditional therapies lack targeted regulation of key mechanisms such as inflammation control, angiogenesis, collagen remodeling, and re-epithelialization. The exosome-hydrogel system enhances wound repair through targeted modulation of these mechanisms and provides effective protection against bacterial infection, hypoxia, excessive oxidative stress, and hyperglycemic microenvironments.</p><p><strong>Conclusion: </strong>The exosome-hydrogel system represents an emerging approach for chronic wound repair and skin regeneration, potentially overcoming the inherent limitations of traditional therapies. Nevertheless, the lack of standardized preparation methods and dosing protocols calls for further optimization.</p>","PeriodicalId":23979,"journal":{"name":"中国修复重建外科杂志","volume":"39 12","pages":"1615-1622"},"PeriodicalIF":0.0,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12705308/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145763946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Application of bridge combined fixation system in pediatric Bado type chronic Monteggia fractures]. [桥式联合固定系统在小儿Bado型Ⅰ慢性Monteggia骨折中的应用]。
Q3 Medicine Pub Date : 2025-12-15 DOI: 10.7507/1002-1892.202509070
De Pan, Xiaoqing He, Ying Xiong, Bolin Yue, Xi Yang, Yongqing Xu, Yongyue Su

Objective: To investigate effectiveness of the bridge combined fixation system (BCFS) for Bado typeⅠchronic Monteggia fractures (CMF) in children.

Methods: A clinical data of 8 children with Bado type ⅠCMF, who were treated with the BCFS between November 2023 and February 2025, was retrospectively analyzed. There were 6 boys and 2 girls, with a mean age of 7.0 years (range, 4-12 years). The time from injury to operation ranged from 29 to 370 days (median, 68.5 days). Preoperative elbow range of motion was (111.3±17.9)° in flexion, (13.1±13.9)° in extension, (71.9±14.6)° in pronation, and (75.6±13.5)° in supination. Fracture healing time and postoperative complications were observed, and clinical outcomes were evaluated using the Mayo elbow performance score.

Results: All incisions healed by primary intention without infection, non-healing of the incision, or iatrogenic nerve injury. All children were followed up 4-18 months (mean, 10.3 months). At last follow-up, the elbow range of motion significantly improved to (142.5±2.7)° in flexion, (2.5±2.7)° in extension, (87.5±2.7)° in pronation, and (88.8±2.3)° in supination ( P<0.05). According to the postoperative Mayo elbow performance score, all cases were rated as excellent. Radiographic review showed no radial head dislocation, nonunion at the ulnar osteotomy site, or elbow stiffness, and no breakage of the BCFS or screw loosening. The fracture healing time ranged from 3 to 6 months, with a median of 4 months.

Conclusion: The BCFS was confirmed to be effective in the treatment of pediatric Bado type Ⅰ CMF, with good restoration of elbow function and the advantage of avoiding secondary implant removal surgery.

目的:探讨桥式联合固定系统(BCFS)治疗儿童Bado型Ⅰ慢性蒙氏骨折(CMF)的疗效。方法:回顾性分析2023年11月至2025年2月8例接受BCFS治疗的Bado型ⅠCMF患儿临床资料。男6例,女2例,平均年龄7.0岁(范围4 ~ 12岁)。损伤至手术时间29 ~ 370天(中位68.5天)。术前肘关节屈曲(111.3±17.9)°,伸展(13.1±13.9)°,旋前(71.9±14.6)°,旋后(75.6±13.5)°。观察骨折愈合时间和术后并发症,并使用Mayo肘关节功能评分评估临床结果。结果:所有切口均顺利愈合,无感染、切口不愈合、医源性神经损伤。所有患儿随访4 ~ 18个月(平均10.3个月)。最后随访时,肘关节屈曲(142.5±2.7)°、伸展(2.5±2.7)°、旋前(87.5±2.7)°、旋后(88.8±2.3)°活动度明显改善(p)。结论:BCFS治疗小儿Bado型ⅠCMF有效,肘关节功能恢复良好,且具有避免二次拔除植入物的优点。
{"title":"[Application of bridge combined fixation system in pediatric Bado type <b>Ⅰ</b> chronic Monteggia fractures].","authors":"De Pan, Xiaoqing He, Ying Xiong, Bolin Yue, Xi Yang, Yongqing Xu, Yongyue Su","doi":"10.7507/1002-1892.202509070","DOIUrl":"10.7507/1002-1892.202509070","url":null,"abstract":"<p><strong>Objective: </strong>To investigate effectiveness of the bridge combined fixation system (BCFS) for Bado typeⅠchronic Monteggia fractures (CMF) in children.</p><p><strong>Methods: </strong>A clinical data of 8 children with Bado type ⅠCMF, who were treated with the BCFS between November 2023 and February 2025, was retrospectively analyzed. There were 6 boys and 2 girls, with a mean age of 7.0 years (range, 4-12 years). The time from injury to operation ranged from 29 to 370 days (median, 68.5 days). Preoperative elbow range of motion was (111.3±17.9)° in flexion, (13.1±13.9)° in extension, (71.9±14.6)° in pronation, and (75.6±13.5)° in supination. Fracture healing time and postoperative complications were observed, and clinical outcomes were evaluated using the Mayo elbow performance score.</p><p><strong>Results: </strong>All incisions healed by primary intention without infection, non-healing of the incision, or iatrogenic nerve injury. All children were followed up 4-18 months (mean, 10.3 months). At last follow-up, the elbow range of motion significantly improved to (142.5±2.7)° in flexion, (2.5±2.7)° in extension, (87.5±2.7)° in pronation, and (88.8±2.3)° in supination ( <i>P</i><0.05). According to the postoperative Mayo elbow performance score, all cases were rated as excellent. Radiographic review showed no radial head dislocation, nonunion at the ulnar osteotomy site, or elbow stiffness, and no breakage of the BCFS or screw loosening. The fracture healing time ranged from 3 to 6 months, with a median of 4 months.</p><p><strong>Conclusion: </strong>The BCFS was confirmed to be effective in the treatment of pediatric Bado type Ⅰ CMF, with good restoration of elbow function and the advantage of avoiding secondary implant removal surgery.</p>","PeriodicalId":23979,"journal":{"name":"中国修复重建外科杂志","volume":"39 12","pages":"1516-1520"},"PeriodicalIF":0.0,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12705328/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145763975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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