Objective: To explore the application and research progress of tissue-engineered scaffolds in the treatment of long-segment laryngotracheal stenosis (LTS).
Methods: A comprehensive review of relevant domestic and international literature was conducted to summarize and analyze the application of different tissue-engineered scaffolds in the treatment of long-segment LTS, including the use of natural materials, synthetic polymers, their composite materials, and biodegradable metals.
Results: Conventional treatment methods for long-segment LTS are often limited in efficacy and associated with a high risk of complications. Tissue-engineered scaffolds can simulate the extracellular matrix and provide a suitable microenvironment for cellular growth, effectively supporting and promoting the repair and regeneration of laryngotracheal tissues. However, different scaffold materials exhibit distinct characteristics in terms of performance and clinical application. Natural materials offer good biocompatibility but insufficient mechanical strength and overly rapid degradation; synthetic polymers provide tunable mechanics but weak bioactivity and a tendency to induce inflammation; composite materials integrate the advantages of both, combining bioactivity with structural strength; biodegradable metal stents possess high mechanical strength and favorable degradability, but optimization of corrosion rate and the safety of degradation products is still required.
Conclusion: Tissue-engineered scaffolds offer a novel therapeutic approach for long-segment LTS. However, further research and optimization of scaffold materials and design are required to enhance treatment efficacy and clinical outcomes.
{"title":"[Application and challenges of tissue engineered scaffolds in treatment of long-segment laryngotracheal stenosis].","authors":"Qingli Yu, Juanjuan Hu, Hui Yang, Yijun Dong, Wei Mo, Ming Xiong, Yaya Gao, Pinfu Zeng","doi":"10.7507/1002-1892.202510021","DOIUrl":"10.7507/1002-1892.202510021","url":null,"abstract":"<p><strong>Objective: </strong>To explore the application and research progress of tissue-engineered scaffolds in the treatment of long-segment laryngotracheal stenosis (LTS).</p><p><strong>Methods: </strong>A comprehensive review of relevant domestic and international literature was conducted to summarize and analyze the application of different tissue-engineered scaffolds in the treatment of long-segment LTS, including the use of natural materials, synthetic polymers, their composite materials, and biodegradable metals.</p><p><strong>Results: </strong>Conventional treatment methods for long-segment LTS are often limited in efficacy and associated with a high risk of complications. Tissue-engineered scaffolds can simulate the extracellular matrix and provide a suitable microenvironment for cellular growth, effectively supporting and promoting the repair and regeneration of laryngotracheal tissues. However, different scaffold materials exhibit distinct characteristics in terms of performance and clinical application. Natural materials offer good biocompatibility but insufficient mechanical strength and overly rapid degradation; synthetic polymers provide tunable mechanics but weak bioactivity and a tendency to induce inflammation; composite materials integrate the advantages of both, combining bioactivity with structural strength; biodegradable metal stents possess high mechanical strength and favorable degradability, but optimization of corrosion rate and the safety of degradation products is still required.</p><p><strong>Conclusion: </strong>Tissue-engineered scaffolds offer a novel therapeutic approach for long-segment LTS. However, further research and optimization of scaffold materials and design are required to enhance treatment efficacy and clinical outcomes.</p>","PeriodicalId":23979,"journal":{"name":"中国修复重建外科杂志","volume":"40 2","pages":"328-335"},"PeriodicalIF":0.0,"publicationDate":"2026-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12948515/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147277393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-15DOI: 10.7507/1002-1892.202510045
Ting Yan, Jun Zeng, Xu Lin, Tao Li, Chao Wu
<p><strong>Objective: </strong>To investigate the risk factors of facet joint excessive resection and its influence on effectiveness after the treatment of degenerative lumbar diseases under large-channel endoscope.</p><p><strong>Methods: </strong>The clinical data of 212 patients with degenerative lumbar diseases treated with large-channel spinal endoscopic technology between June 2022 and June 2024 were retrospectively analyzed. Among them, 120 were male and 92 were female. The age ranged from 18 to 85 years, with an average of 54 years. According to the facet joint resection rate measured by CT after operation, the patients were divided into preservation group (facet joint preservation rate≥50%) and excessive resection group (facet joint preservation rate<50%). Visual analogue scale (VAS) score for low back and leg pain, Oswestry disability index (ODI), and Japanese Orthopaedic Association (JOA) scores were used to evaluate the improvement of pain and function before operation, at 1 month after operation, and at last follow-up, and the modified MacNab criteria were used to evaluate the effectiveness at last follow-up. The occurrence of lumbar instability was observed during follow-up. Univariate analysis was performed on variables including gender, age, body mass index, responsible segment, surgical side, whether over-top decompression was performed, whether presence of lateral recess stenosis, whether presence of intervertebral disc calcification, whether presence of lumbosacral transitional vertebrae, whether presence of facet joint hyperplasia, and imaging parameters [facet joint angle (FJA), laminar lateral-oblique angle, maximum width between the medial and lateral margins of the superior articular facet on axial CT (d <sub>1</sub>), distance between the base of the ipsilateral spinous process and the midline of the facet joint at the responsible segment (d <sub>2</sub>), as well as the width (d <sub>3</sub>) and height (d <sub>4</sub>) of the interlaminar space at the responsible segment on anteroposterior X-ray films] between the preservation group and the excessive resection group. And logistic regression analysis was further used to identify risk factors for facet joint excessive resection.</p><p><strong>Results: </strong>All patients underwent operative procedures successfully, and all incisions healed by first intention. No complication such as vascular and nerve injury, infection, and spinal cord hypertension-like syndrome occurred. There were 55 patients enrolled in the excessive resection group, and 157 patients in the preservation group. All patients were followed up 12-36 months, with a mean of 23.5 months. There was no significant difference in low back pain VAS score, leg pain VAS score, ODI, and JOA score between the two groups preoperatively ( <i>P></i>0.05). The low back pain VAS score, ODI of the excessive resection group were significantly higher than those of the preservation group, and JOA score was significantly lower
{"title":"[Risk factor analysis of excessive resection of facet joint after large-channel spinal endoscopic depression for degenerative lumbar diseases].","authors":"Ting Yan, Jun Zeng, Xu Lin, Tao Li, Chao Wu","doi":"10.7507/1002-1892.202510045","DOIUrl":"10.7507/1002-1892.202510045","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the risk factors of facet joint excessive resection and its influence on effectiveness after the treatment of degenerative lumbar diseases under large-channel endoscope.</p><p><strong>Methods: </strong>The clinical data of 212 patients with degenerative lumbar diseases treated with large-channel spinal endoscopic technology between June 2022 and June 2024 were retrospectively analyzed. Among them, 120 were male and 92 were female. The age ranged from 18 to 85 years, with an average of 54 years. According to the facet joint resection rate measured by CT after operation, the patients were divided into preservation group (facet joint preservation rate≥50%) and excessive resection group (facet joint preservation rate<50%). Visual analogue scale (VAS) score for low back and leg pain, Oswestry disability index (ODI), and Japanese Orthopaedic Association (JOA) scores were used to evaluate the improvement of pain and function before operation, at 1 month after operation, and at last follow-up, and the modified MacNab criteria were used to evaluate the effectiveness at last follow-up. The occurrence of lumbar instability was observed during follow-up. Univariate analysis was performed on variables including gender, age, body mass index, responsible segment, surgical side, whether over-top decompression was performed, whether presence of lateral recess stenosis, whether presence of intervertebral disc calcification, whether presence of lumbosacral transitional vertebrae, whether presence of facet joint hyperplasia, and imaging parameters [facet joint angle (FJA), laminar lateral-oblique angle, maximum width between the medial and lateral margins of the superior articular facet on axial CT (d <sub>1</sub>), distance between the base of the ipsilateral spinous process and the midline of the facet joint at the responsible segment (d <sub>2</sub>), as well as the width (d <sub>3</sub>) and height (d <sub>4</sub>) of the interlaminar space at the responsible segment on anteroposterior X-ray films] between the preservation group and the excessive resection group. And logistic regression analysis was further used to identify risk factors for facet joint excessive resection.</p><p><strong>Results: </strong>All patients underwent operative procedures successfully, and all incisions healed by first intention. No complication such as vascular and nerve injury, infection, and spinal cord hypertension-like syndrome occurred. There were 55 patients enrolled in the excessive resection group, and 157 patients in the preservation group. All patients were followed up 12-36 months, with a mean of 23.5 months. There was no significant difference in low back pain VAS score, leg pain VAS score, ODI, and JOA score between the two groups preoperatively ( <i>P></i>0.05). The low back pain VAS score, ODI of the excessive resection group were significantly higher than those of the preservation group, and JOA score was significantly lower","PeriodicalId":23979,"journal":{"name":"中国修复重建外科杂志","volume":"40 2","pages":"227-233"},"PeriodicalIF":0.0,"publicationDate":"2026-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12948503/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147277299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-15DOI: 10.7507/1002-1892.202601151
National Health Commission Of The People's Republic Of China
In order to improve the ability and level of medical emergency treatment for burn, the National Health Commission organized experts from the National Trauma Medical Center (Peking University People's Hospital) and the National Orthopaedic Medical Center (Beijing Jishuitan Hospital Affiliated to Capital Medical University) to formulate the Medical Treatment Standards for Emergency Burn Wounded (2025 Edition). The main contents of the norms include the assessment of the severity of burns, first aid and transportation, medical treatment, prevention and treatment of complications, etc., for reference and implementation in the medical emergency response to emergencies.
{"title":"[Medical treatment standards for emergency burn wounded (2025 edition)].","authors":"National Health Commission Of The People's Republic Of China","doi":"10.7507/1002-1892.202601151","DOIUrl":"10.7507/1002-1892.202601151","url":null,"abstract":"<p><p>In order to improve the ability and level of medical emergency treatment for burn, the National Health Commission organized experts from the National Trauma Medical Center (Peking University People's Hospital) and the National Orthopaedic Medical Center (Beijing Jishuitan Hospital Affiliated to Capital Medical University) to formulate the Medical Treatment Standards for Emergency Burn Wounded (2025 Edition). The main contents of the norms include the assessment of the severity of burns, first aid and transportation, medical treatment, prevention and treatment of complications, <i>etc</i>., for reference and implementation in the medical emergency response to emergencies.</p>","PeriodicalId":23979,"journal":{"name":"中国修复重建外科杂志","volume":"40 2","pages":"185-196"},"PeriodicalIF":0.0,"publicationDate":"2026-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12948514/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147277322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-15DOI: 10.7507/1002-1892.202509098
Yonghui Zhao, Cheng Wang
<p><strong>Objective: </strong>To investigate the impact of tibial tunnel position on postoperative knee function and stability in patients undergoing artificial posterior cruciate ligament (PCL) reconstruction.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on patients who underwent single knee artificial PCL reconstruction between January 2018 and September 2024 and met the inclusion criteria. Based on postoperative three-dimensional (3D)-CT measurements of the tibial tunnel position, the patients were allocated into a low tunnel group ( <i>n</i>=35) and a high tunnel group ( <i>n</i>=30). Except for gender, there was no significant difference between groups ( <i>P</i>>0.05) in age, body mass index, injury side, time from injury to operation, preoperative posterior drawer test grade, knee range of motion (ROM), Tegner score, Lysholm score, International Knee Documentation Committee (IKDC) score, or the composition ratio of combined meniscus and cartilage injuries. The tibial tunnel positions were compared. Postoperative recovery of knee function was evaluated using the IKDC score, Lysholm score, Tegner score, and knee ROM. The differences between pre- and post-operative values (change values) for these indicators were calculated and compared between groups. Posterior knee stability was assessed using the posterior drawer test and the side-to-side difference (SSD) in tibial posterior translation measured on stress radiographs. Patient satisfaction was evaluated using the visual analogue scale (VAS) score. Postoperative complications such as graft failure were recorded.</p><p><strong>Results: </strong>The relative proximal-distal position of the tibial tunnel was significantly lower in the low tunnel group than in the high tunnel group ( <i>P</i><0.05), while no significant difference was found in the relative medial-lateral position between groups ( <i>P</i>>0.05). All operations were successfully completed, and incisions healed by first intention. All patients were followed up 12-86 months, with a median follow-up of 23.0 months. The low tunnel group demonstrated superior posterior stability compared to the high tunnel group, showing a significantly lower SSD and lower posterior drawer test grade at last follow-up ( <i>P</i><0.05). At last follow-up, the change value in the Tegner score and the VAS score for patient satisfaction were significantly higher in the low tunnel group than in the high tunnel group ( <i>P</i><0.05). No significant difference was found between groups in the change values for IKDC score, Lysholm score, or knee ROM ( <i>P</i>>0.05). Two patients in the high tunnel group underwent revision surgery due to graft failure, whereas no such adverse events occurred in the low tunnel group. The difference in the incidence of complications between groups was not significant ( <i>P</i>>0.05).</p><p><strong>Conclusion: </strong>Compared with a high tibial tunnel, the low tibial tunnel technique can effectively
{"title":"[Impact of tibial tunnel position in artificial posterior cruciate ligament reconstruction on postoperative knee function and stability].","authors":"Yonghui Zhao, Cheng Wang","doi":"10.7507/1002-1892.202509098","DOIUrl":"10.7507/1002-1892.202509098","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the impact of tibial tunnel position on postoperative knee function and stability in patients undergoing artificial posterior cruciate ligament (PCL) reconstruction.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on patients who underwent single knee artificial PCL reconstruction between January 2018 and September 2024 and met the inclusion criteria. Based on postoperative three-dimensional (3D)-CT measurements of the tibial tunnel position, the patients were allocated into a low tunnel group ( <i>n</i>=35) and a high tunnel group ( <i>n</i>=30). Except for gender, there was no significant difference between groups ( <i>P</i>>0.05) in age, body mass index, injury side, time from injury to operation, preoperative posterior drawer test grade, knee range of motion (ROM), Tegner score, Lysholm score, International Knee Documentation Committee (IKDC) score, or the composition ratio of combined meniscus and cartilage injuries. The tibial tunnel positions were compared. Postoperative recovery of knee function was evaluated using the IKDC score, Lysholm score, Tegner score, and knee ROM. The differences between pre- and post-operative values (change values) for these indicators were calculated and compared between groups. Posterior knee stability was assessed using the posterior drawer test and the side-to-side difference (SSD) in tibial posterior translation measured on stress radiographs. Patient satisfaction was evaluated using the visual analogue scale (VAS) score. Postoperative complications such as graft failure were recorded.</p><p><strong>Results: </strong>The relative proximal-distal position of the tibial tunnel was significantly lower in the low tunnel group than in the high tunnel group ( <i>P</i><0.05), while no significant difference was found in the relative medial-lateral position between groups ( <i>P</i>>0.05). All operations were successfully completed, and incisions healed by first intention. All patients were followed up 12-86 months, with a median follow-up of 23.0 months. The low tunnel group demonstrated superior posterior stability compared to the high tunnel group, showing a significantly lower SSD and lower posterior drawer test grade at last follow-up ( <i>P</i><0.05). At last follow-up, the change value in the Tegner score and the VAS score for patient satisfaction were significantly higher in the low tunnel group than in the high tunnel group ( <i>P</i><0.05). No significant difference was found between groups in the change values for IKDC score, Lysholm score, or knee ROM ( <i>P</i>>0.05). Two patients in the high tunnel group underwent revision surgery due to graft failure, whereas no such adverse events occurred in the low tunnel group. The difference in the incidence of complications between groups was not significant ( <i>P</i>>0.05).</p><p><strong>Conclusion: </strong>Compared with a high tibial tunnel, the low tibial tunnel technique can effectively","PeriodicalId":23979,"journal":{"name":"中国修复重建外科杂志","volume":"40 2","pages":"258-264"},"PeriodicalIF":0.0,"publicationDate":"2026-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12948518/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147276993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-15DOI: 10.7507/1002-1892.202511084
Yi Ye, Bing Lu, Jiahong Li, Kun Zhang
The American Academy of Orthopaedic Surgeons (AAOS) released the updated Evidence-Based Clinical Practice Guideline for the Management of Rotator Cuff Injuries in August 2025. The guideline provides 25 recommendations and 4 consensus statements across diagnosis, treatment decision-making, biologic interventions, and postoperative rehabilitation, with the strength of each recommendation graded according to the quality of supporting evidence. The updated guideline highlights several key advances, including establishing CT as an important adjunctive imaging modality, providing specific recommendations on repair strategies for high-grade partial-thickness rotator cuff tears, and clearly restricting the use of platelet-rich plasma and marrow stimulation in rotator cuff repair, as well as limiting the application of prolotherapy in the treatment of full-thickness rotator cuff tears. In addition, the guideline emphasizes the potential benefits of early mobilization in patients with small to medium-sized tears.
{"title":"[Interpretation of the 2025 American Academy of Orthopaedic Surgeons (AAOS) on Management of Rotator Cuff Injuries Evidence-Based Clinical Practice Guideline].","authors":"Yi Ye, Bing Lu, Jiahong Li, Kun Zhang","doi":"10.7507/1002-1892.202511084","DOIUrl":"10.7507/1002-1892.202511084","url":null,"abstract":"<p><p>The American Academy of Orthopaedic Surgeons (AAOS) released the updated Evidence-Based Clinical Practice Guideline for the Management of Rotator Cuff Injuries in August 2025. The guideline provides 25 recommendations and 4 consensus statements across diagnosis, treatment decision-making, biologic interventions, and postoperative rehabilitation, with the strength of each recommendation graded according to the quality of supporting evidence. The updated guideline highlights several key advances, including establishing CT as an important adjunctive imaging modality, providing specific recommendations on repair strategies for high-grade partial-thickness rotator cuff tears, and clearly restricting the use of platelet-rich plasma and marrow stimulation in rotator cuff repair, as well as limiting the application of prolotherapy in the treatment of full-thickness rotator cuff tears. In addition, the guideline emphasizes the potential benefits of early mobilization in patients with small to medium-sized tears.</p>","PeriodicalId":23979,"journal":{"name":"中国修复重建外科杂志","volume":"40 2","pages":"197-203"},"PeriodicalIF":0.0,"publicationDate":"2026-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12948511/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147277304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-15DOI: 10.7507/1002-1892.202601150
National Health Commission Of The People's Republic Of China
In order to improve the ability and level of medical emergency treatment for trauma, the National Health Commission organized experts from the National Trauma Medical Center (Peking University People's Hospital) and the National Orthopaedic Medical Center (Beijing Jishuitan Hospital Affiliated to Capital Medical University) to formulate the Medical Treatment Standards for Emergency Trauma Wounded (2025 Edition). The main contents of the norms include the assessment of the severity of trauma, first aid and transportation, medical treatment, prevention and treatment of complications, etc., for reference and implementation in the medical emergency response to emergencies.
{"title":"[Medical treatment standards for emergency trauma wounded (2025 edition)].","authors":"National Health Commission Of The People's Republic Of China","doi":"10.7507/1002-1892.202601150","DOIUrl":"10.7507/1002-1892.202601150","url":null,"abstract":"<p><p>In order to improve the ability and level of medical emergency treatment for trauma, the National Health Commission organized experts from the National Trauma Medical Center (Peking University People's Hospital) and the National Orthopaedic Medical Center (Beijing Jishuitan Hospital Affiliated to Capital Medical University) to formulate the Medical Treatment Standards for Emergency Trauma Wounded (2025 Edition). The main contents of the norms include the assessment of the severity of trauma, first aid and transportation, medical treatment, prevention and treatment of complications, <i>etc</i>., for reference and implementation in the medical emergency response to emergencies.</p>","PeriodicalId":23979,"journal":{"name":"中国修复重建外科杂志","volume":"40 2","pages":"176-184"},"PeriodicalIF":0.0,"publicationDate":"2026-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12948509/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147277319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-15DOI: 10.7507/1002-1892.202509072
Jin Wang, Duohui Xu, Jide Wu, Yanchuan Pu
Objective: To evaluate the feasibility and effectiveness of a novel locking anatomical plate designed for the acromial end of the clavicle (hereinafter referred to as the "novel locking plate") in the treatment of Neer type Ⅱb and type Ⅴ distal clavicle fractures.
Methods: Between February 2024 and January 2025, a total of 12 patients with Neer type Ⅱb and type Ⅴ distal clavicle fractures resulting from trauma were treated using the novel locking plate. The cohort comprised 7 males and 5 females, with ages ranging from 22 to 65 years (mean, 49.6 years). According to the Neer fracture classification system, 9 cases were classified as type Ⅱb and 3 cases as type Ⅴ. The interval from injury to operation ranged from 2 to 6 days (mean, 3.9 days). After achieving anatomical reduction of the fracture, the novel locking plate was applied for internal fixation, accompanied by anatomical reconstruction of the coracoclavicular ligament. The operation time, intraoperative blood loss, and incision healing were meticulously documented. During follow-up, the radiographic examinations were taken to assess fracture healing, and the shoulder joint function was evaluated using the Constant-Murley score criteria.
Results: All 12 operations were completed. The operation time ranged from 55 to 90 minutes (mean, 74 minutes), and intraoperative blood loss ranged from 50 to 100 mL (mean, 85 mL). All incisions healed by first intention. All patients were followed up 6-18 months (mean, 11.6 months). At last follow-up, the radiographic examination demonstrated that all fractures had achieved bony union; the Constant-Murley score ranged from 92 to 96 (mean, 94.3), all rated as excellent.
Conclusion: For Neer type Ⅱb and type Ⅴ distal clavicle fractures, the combination of the novel locking plate fixation and anatomical reconstruction of the coracoclavicular ligament provides reliable internal fixation, promotes fracture healing, and yields highly satisfactory effectiveness.
{"title":"[Application study of a novel locking anatomical plate in treatment of Neer type <b>Ⅱ</b>b and type <b>Ⅴ</b> distal clavicle fractures].","authors":"Jin Wang, Duohui Xu, Jide Wu, Yanchuan Pu","doi":"10.7507/1002-1892.202509072","DOIUrl":"10.7507/1002-1892.202509072","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the feasibility and effectiveness of a novel locking anatomical plate designed for the acromial end of the clavicle (hereinafter referred to as the \"novel locking plate\") in the treatment of Neer type Ⅱb and type Ⅴ distal clavicle fractures.</p><p><strong>Methods: </strong>Between February 2024 and January 2025, a total of 12 patients with Neer type Ⅱb and type Ⅴ distal clavicle fractures resulting from trauma were treated using the novel locking plate. The cohort comprised 7 males and 5 females, with ages ranging from 22 to 65 years (mean, 49.6 years). According to the Neer fracture classification system, 9 cases were classified as type Ⅱb and 3 cases as type Ⅴ. The interval from injury to operation ranged from 2 to 6 days (mean, 3.9 days). After achieving anatomical reduction of the fracture, the novel locking plate was applied for internal fixation, accompanied by anatomical reconstruction of the coracoclavicular ligament. The operation time, intraoperative blood loss, and incision healing were meticulously documented. During follow-up, the radiographic examinations were taken to assess fracture healing, and the shoulder joint function was evaluated using the Constant-Murley score criteria.</p><p><strong>Results: </strong>All 12 operations were completed. The operation time ranged from 55 to 90 minutes (mean, 74 minutes), and intraoperative blood loss ranged from 50 to 100 mL (mean, 85 mL). All incisions healed by first intention. All patients were followed up 6-18 months (mean, 11.6 months). At last follow-up, the radiographic examination demonstrated that all fractures had achieved bony union; the Constant-Murley score ranged from 92 to 96 (mean, 94.3), all rated as excellent.</p><p><strong>Conclusion: </strong>For Neer type Ⅱb and type Ⅴ distal clavicle fractures, the combination of the novel locking plate fixation and anatomical reconstruction of the coracoclavicular ligament provides reliable internal fixation, promotes fracture healing, and yields highly satisfactory effectiveness.</p>","PeriodicalId":23979,"journal":{"name":"中国修复重建外科杂志","volume":"40 2","pages":"248-251"},"PeriodicalIF":0.0,"publicationDate":"2026-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12948498/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147277435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-15DOI: 10.7507/1002-1892.202509009
Rongzhi Jia, Yang Xue, Dehai Kong, Yang Zhang, Guangchao Sun
<p><strong>Objective: </strong>To investigate the effectiveness of all-arthroscopic gastrocnemius aponeurosis release and Achilles tendon insertion debridement in the treatment of Haglund's disease complicated with gastrocnemius aponeurosis contracture.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on the clinical data of 50 patients with Haglund's disease complicated by gastrocnemius aponeurosis contracture, who were admitted and met the selection criteria between April 2020 and March 2022. Based on the surgical approach, the patients were divided into an observation group (26 cases, 26 feet, undergoing all-arthroscopic gastrocnemius aponeurosis release and Achilles tendon insertion debridement) and a control group (24 cases, 24 feet, undergoing open Achilles tendon insertion debridement only). There was no significant difference ( <i>P</i>>0.05) in baseline data between the two groups, including gender, age, body mass index, affected side, preoperative Fowler-Philip angle (FPA), visual analogue scale (VAS) score, American Orthopaedic Foot & Ankle Society (AOFAS) ankle-hindfoot score, Victorian Institute of Sport Assessment-Achilles (VISA-A) score, and ankle dorsiflexion range of motion (ROM). Surgical duration, incision length, intraoperative blood loss, time to return to daily activities and sports, and incidence of complications were recorded and compared between the two groups. FPA was measured at 1 month after operation and the changes before and after operation were calculated. Functional recovery was evaluated by comparing VAS score, AOFAS ankle-hindfoot score, VISA-A score, and ankle dorsiflexion ROM before operation and at 1, 3, 12 months after operation.</p><p><strong>Results: </strong>The observation group had a longer surgical duration but lower intraoperative blood loss and shorter incision length compared to the control group, with all differences being significant ( <i>P</i><0.05). One patient in the observation group experienced postoperative limb numbness, while 3 patients in the control group developed incision redness and swelling, all of which resolved after symptomatic treatment. The remaining patients showed good postoperative incision healing, with no complication such as infection or neurovascular injury occurring in any case. All patients were followed up 12-20 months, with an average of 18.3 months. The observation group had shorter recovery time for both daily activities and sports activities compared to the control group ( <i>P</i><0.05). There was no significant difference between the two groups in the preoperative to postoperative change in FPA ( <i>P</i>>0.05). In both groups, the VAS scores, AOFAS ankle-hindfoot scores, VISA-A scores, and ankle dorsiflexion ROM showed significant improvement at each postoperative time point compared with preoperative values, furthermore, all these indicators continued to improve progressively over time postoperatively, with all differences being significan
{"title":"[Effectiveness of all-arthroscopic gastrocnemius aponeurosis release and Achilles tendon insertion debridement in treatment of Haglund's disease].","authors":"Rongzhi Jia, Yang Xue, Dehai Kong, Yang Zhang, Guangchao Sun","doi":"10.7507/1002-1892.202509009","DOIUrl":"10.7507/1002-1892.202509009","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the effectiveness of all-arthroscopic gastrocnemius aponeurosis release and Achilles tendon insertion debridement in the treatment of Haglund's disease complicated with gastrocnemius aponeurosis contracture.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on the clinical data of 50 patients with Haglund's disease complicated by gastrocnemius aponeurosis contracture, who were admitted and met the selection criteria between April 2020 and March 2022. Based on the surgical approach, the patients were divided into an observation group (26 cases, 26 feet, undergoing all-arthroscopic gastrocnemius aponeurosis release and Achilles tendon insertion debridement) and a control group (24 cases, 24 feet, undergoing open Achilles tendon insertion debridement only). There was no significant difference ( <i>P</i>>0.05) in baseline data between the two groups, including gender, age, body mass index, affected side, preoperative Fowler-Philip angle (FPA), visual analogue scale (VAS) score, American Orthopaedic Foot & Ankle Society (AOFAS) ankle-hindfoot score, Victorian Institute of Sport Assessment-Achilles (VISA-A) score, and ankle dorsiflexion range of motion (ROM). Surgical duration, incision length, intraoperative blood loss, time to return to daily activities and sports, and incidence of complications were recorded and compared between the two groups. FPA was measured at 1 month after operation and the changes before and after operation were calculated. Functional recovery was evaluated by comparing VAS score, AOFAS ankle-hindfoot score, VISA-A score, and ankle dorsiflexion ROM before operation and at 1, 3, 12 months after operation.</p><p><strong>Results: </strong>The observation group had a longer surgical duration but lower intraoperative blood loss and shorter incision length compared to the control group, with all differences being significant ( <i>P</i><0.05). One patient in the observation group experienced postoperative limb numbness, while 3 patients in the control group developed incision redness and swelling, all of which resolved after symptomatic treatment. The remaining patients showed good postoperative incision healing, with no complication such as infection or neurovascular injury occurring in any case. All patients were followed up 12-20 months, with an average of 18.3 months. The observation group had shorter recovery time for both daily activities and sports activities compared to the control group ( <i>P</i><0.05). There was no significant difference between the two groups in the preoperative to postoperative change in FPA ( <i>P</i>>0.05). In both groups, the VAS scores, AOFAS ankle-hindfoot scores, VISA-A scores, and ankle dorsiflexion ROM showed significant improvement at each postoperative time point compared with preoperative values, furthermore, all these indicators continued to improve progressively over time postoperatively, with all differences being significan","PeriodicalId":23979,"journal":{"name":"中国修复重建外科杂志","volume":"40 2","pages":"285-290"},"PeriodicalIF":0.0,"publicationDate":"2026-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12948499/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147276969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
<p><strong>Objective: </strong>To elucidate the role of interleukin-33 (IL-33) in glucocorticoid-induced osteonecrosis of the femoral head (ONFH) in mice, with particular emphasis on its effects on bone remodeling, inflammatory regulation, and fibrosis.</p><p><strong>Methods: </strong><i>In vivo</i>: Fifteen 9-week-old male C57BL/6J wild-type mice were randomly divided into a normal control group, an ONFH group, and an intervention group, with 5 mice in each group. A glucocorticoid-induced ONFH model was established in the ONFH group and intervention group using a combined administration of lipopolysaccharide and methylprednisolone. The intervention group received intraperitoneal injection of IL-33 for 4 consecutive days during the early stage of model establishment; the normal control group received saline injection at the same time points. General conditions of mice were observed during the experiment. Endogenous IL-33 and transmembrane ST2 (ST2 ligand, ST2L) expression in the femoral head was assessed via immunofluorescence, quantitative PCR (qPCR), and Western blot. Bone necrosis and fibrosis were evaluated using HE and Masson staining. Immunohistochemistry was performed to detect osteogenic markers [osteocalcin (OCN), osteopontin (OPN), Runt-related transcription factor 2 (Runx2)] and osteoclastic marker (receptor activator of nuclear factor-κB ligand, RANKL), while serum cytokine levels [tumor necrosis factor (TNF-α), IL-6, IL-1β, IL-4, IL-10] were quantified by ELISA. <i>In vitro</i>: Murine osteoblasts were divided into control group (DMEM+PBS), IL-33 group (DMEM+10 ng/mL IL-33), and IL-33+ST2L group (DMEM+10 ng/mL IL-33+1 μg/mL ST2L antibody). After corresponding treatment, cell proliferation was detected by EdU incorporation assay. Additional osteoblasts were subjected to osteogenic induction culture, and mineralization, and the expression of osteogenesis-related genes (Runx2, collagen type Ⅰ, OCN, and OPN) were assessed by using alkaline phosphatase (ALP) staining, Alizarin red staining, and qPCR, respectively.</p><p><strong>Results: </strong><i>In vivo</i>: All animals survived until the completion of the experiment. Mice in the intervention group and ONFH group showed restricted mobility. Compared with the normal control group, the expressions of IL-33 and ST2L significantly upregulated at both mRNA and protein levels ( <i>P</i><0.05). Exogenous IL-33 administration exacerbated, rather than ameliorated, trabecular destruction and fibrosis, with the intervention group showing significantly increased fibrosis area percentage and empty lacunae rate compared with the other two groups ( <i>P</i><0.05). Furthermore, IL-33 treatment further suppressed the expressions of osteogenic markers (Runx2, OCN, OPN) while significantly enhancing the expression of the osteoclastic marker (RANKL) ( <i>P</i><0.05). ELISA results showed that compared with the ONFH group, serum levels of pro-inflammatory cytokines (IL-4, IL-6, IL-1β) were significantly lo
{"title":"[Effect of interleukin-33 on glucocorticoid-induced osteonecrosis of the femoral head in mice].","authors":"Hongxu Li, Mengran Shen, Haoyang Liu, Yu Zhou, Fuqiang Gao, Liming Cheng, Bailiang Wang, Jinhui Ma","doi":"10.7507/1002-1892.202506101","DOIUrl":"10.7507/1002-1892.202506101","url":null,"abstract":"<p><strong>Objective: </strong>To elucidate the role of interleukin-33 (IL-33) in glucocorticoid-induced osteonecrosis of the femoral head (ONFH) in mice, with particular emphasis on its effects on bone remodeling, inflammatory regulation, and fibrosis.</p><p><strong>Methods: </strong><i>In vivo</i>: Fifteen 9-week-old male C57BL/6J wild-type mice were randomly divided into a normal control group, an ONFH group, and an intervention group, with 5 mice in each group. A glucocorticoid-induced ONFH model was established in the ONFH group and intervention group using a combined administration of lipopolysaccharide and methylprednisolone. The intervention group received intraperitoneal injection of IL-33 for 4 consecutive days during the early stage of model establishment; the normal control group received saline injection at the same time points. General conditions of mice were observed during the experiment. Endogenous IL-33 and transmembrane ST2 (ST2 ligand, ST2L) expression in the femoral head was assessed via immunofluorescence, quantitative PCR (qPCR), and Western blot. Bone necrosis and fibrosis were evaluated using HE and Masson staining. Immunohistochemistry was performed to detect osteogenic markers [osteocalcin (OCN), osteopontin (OPN), Runt-related transcription factor 2 (Runx2)] and osteoclastic marker (receptor activator of nuclear factor-κB ligand, RANKL), while serum cytokine levels [tumor necrosis factor (TNF-α), IL-6, IL-1β, IL-4, IL-10] were quantified by ELISA. <i>In vitro</i>: Murine osteoblasts were divided into control group (DMEM+PBS), IL-33 group (DMEM+10 ng/mL IL-33), and IL-33+ST2L group (DMEM+10 ng/mL IL-33+1 μg/mL ST2L antibody). After corresponding treatment, cell proliferation was detected by EdU incorporation assay. Additional osteoblasts were subjected to osteogenic induction culture, and mineralization, and the expression of osteogenesis-related genes (Runx2, collagen type Ⅰ, OCN, and OPN) were assessed by using alkaline phosphatase (ALP) staining, Alizarin red staining, and qPCR, respectively.</p><p><strong>Results: </strong><i>In vivo</i>: All animals survived until the completion of the experiment. Mice in the intervention group and ONFH group showed restricted mobility. Compared with the normal control group, the expressions of IL-33 and ST2L significantly upregulated at both mRNA and protein levels ( <i>P</i><0.05). Exogenous IL-33 administration exacerbated, rather than ameliorated, trabecular destruction and fibrosis, with the intervention group showing significantly increased fibrosis area percentage and empty lacunae rate compared with the other two groups ( <i>P</i><0.05). Furthermore, IL-33 treatment further suppressed the expressions of osteogenic markers (Runx2, OCN, OPN) while significantly enhancing the expression of the osteoclastic marker (RANKL) ( <i>P</i><0.05). ELISA results showed that compared with the ONFH group, serum levels of pro-inflammatory cytokines (IL-4, IL-6, IL-1β) were significantly lo","PeriodicalId":23979,"journal":{"name":"中国修复重建外科杂志","volume":"40 2","pages":"291-301"},"PeriodicalIF":0.0,"publicationDate":"2026-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12948520/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147276956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-15DOI: 10.7507/1002-1892.202509077
Chengyu Huang, Kai Chen, Honglin Liu, Zhilin Ge, Dingkun Lin, Bolai Chen, Guoyi Su, Yongpeng Lin, Yu Hou, Yongjin Li
Objective: To compare the effectiveness of endoscopic anterior cervical discectomy and fusion (Endo-ACDF) and microscope-assisted ACDF (Micro-ACDF) in the treatment of single-level cervical spondylotic myelopathy (CSM).
Methods: A retrospective analysis was conducted on the clinical data of 44 patients with single-level CSM who underwent ACDF between February 2022 and January 2024 and met the selection criteria. These patients were divided into Endo-ACDF group (22 cases) and Micro-ACDF group (22 cases). There was no significant difference ( P>0.05) between the two groups in baseline data, including gender, age, body mass index, disease duration, surgical level, and preoperative Japanese Orthopaedic Association (JOA) score, Cobb angle, and the degree of prevertebral soft tissue swelling (PSTS) at C 2-6. The operation time, postoperative hospital stay, intraoperative blood loss, postoperative drainage volume, total blood loss, and hidden blood loss were recorded and compared between the two groups. The Cobb angle and PSTS degree at C 2-6 were measured based on X-ray films at 2-3 days after operation. The JOA score was used to assess spinal cord function at 1 year after operation. The differences between pre- and post-operation (change values) in these indicators were calculated and compared between groups.
Results: All operations in both groups were successfully completed. Compared to the Micro-ACDF group, the Endo-ACDF group had significantly longer operation time and significantly lower total blood loss and hidden blood loss ( P<0.05). No significant difference was found between the two groups in intraoperative blood loss, postoperative hospital stay, or postoperative drainage volume ( P>0.05). No operation-related complication occurred during or after the procedures. All patients were followed up 12-16 months (mean, 13.9 months). At 1 year after operation, the JOA scores and Cobb angles in both groups showed significant improvement compared to preoperative values ( P<0.05). However, the change values for JOA scores and Cobb angles showed no significant difference between the groups ( P>0.05). The postoperative PSTS degree at C 2-6 was significantly different from preoperative values in both groups ( P<0.05), but the change value did not differ significantly between the two groups ( P>0.05). The imaging re-examination showed the satisfactory positioning of the cages and internal fixation.
Conclusion: Both Endo-ACDF and Micro-ACDF provide satisfactory effectiveness in treating single-level CSM, with no significant difference in the PSTS degree. Furthermore, Endo-ACDF is associated with less hidden blood loss.
{"title":"[Comparison of effectiveness between endoscopic and microscopic anterior cervical discectomy and fusion].","authors":"Chengyu Huang, Kai Chen, Honglin Liu, Zhilin Ge, Dingkun Lin, Bolai Chen, Guoyi Su, Yongpeng Lin, Yu Hou, Yongjin Li","doi":"10.7507/1002-1892.202509077","DOIUrl":"10.7507/1002-1892.202509077","url":null,"abstract":"<p><strong>Objective: </strong>To compare the effectiveness of endoscopic anterior cervical discectomy and fusion (Endo-ACDF) and microscope-assisted ACDF (Micro-ACDF) in the treatment of single-level cervical spondylotic myelopathy (CSM).</p><p><strong>Methods: </strong>A retrospective analysis was conducted on the clinical data of 44 patients with single-level CSM who underwent ACDF between February 2022 and January 2024 and met the selection criteria. These patients were divided into Endo-ACDF group (22 cases) and Micro-ACDF group (22 cases). There was no significant difference ( <i>P</i>>0.05) between the two groups in baseline data, including gender, age, body mass index, disease duration, surgical level, and preoperative Japanese Orthopaedic Association (JOA) score, Cobb angle, and the degree of prevertebral soft tissue swelling (PSTS) at C <sub>2-6</sub>. The operation time, postoperative hospital stay, intraoperative blood loss, postoperative drainage volume, total blood loss, and hidden blood loss were recorded and compared between the two groups. The Cobb angle and PSTS degree at C <sub>2-6</sub> were measured based on X-ray films at 2-3 days after operation. The JOA score was used to assess spinal cord function at 1 year after operation. The differences between pre- and post-operation (change values) in these indicators were calculated and compared between groups.</p><p><strong>Results: </strong>All operations in both groups were successfully completed. Compared to the Micro-ACDF group, the Endo-ACDF group had significantly longer operation time and significantly lower total blood loss and hidden blood loss ( <i>P</i><0.05). No significant difference was found between the two groups in intraoperative blood loss, postoperative hospital stay, or postoperative drainage volume ( <i>P</i>>0.05). No operation-related complication occurred during or after the procedures. All patients were followed up 12-16 months (mean, 13.9 months). At 1 year after operation, the JOA scores and Cobb angles in both groups showed significant improvement compared to preoperative values ( <i>P</i><0.05). However, the change values for JOA scores and Cobb angles showed no significant difference between the groups ( <i>P</i>>0.05). The postoperative PSTS degree at C <sub>2-6</sub> was significantly different from preoperative values in both groups ( <i>P</i><0.05), but the change value did not differ significantly between the two groups ( <i>P</i>>0.05). The imaging re-examination showed the satisfactory positioning of the cages and internal fixation.</p><p><strong>Conclusion: </strong>Both Endo-ACDF and Micro-ACDF provide satisfactory effectiveness in treating single-level CSM, with no significant difference in the PSTS degree. Furthermore, Endo-ACDF is associated with less hidden blood loss.</p>","PeriodicalId":23979,"journal":{"name":"中国修复重建外科杂志","volume":"40 2","pages":"219-226"},"PeriodicalIF":0.0,"publicationDate":"2026-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12948510/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147276568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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