Determining the physical development of the population of the regions is quite convenient within the framework of identifying the level of public health, while it is very important to track changes in the physical health of adolescents entering the reproductive phase of life, depending on the periods of development of the country. The aim of this study was to identify significant changes in the morphological profile of adolescents in Penza and Penza region over 15 years. Material and methods. The object of the study were 492 people of both sexes, 16 to 21 years of age, born and permanently residing in Penza and settlements of Penza region, divided into two groups according to the year of birth (group 1 – born in 1986–1990, 2 group – born in 1999–2004). Anthropometry and somatometry were carried out by the method of V.V. Bunak with subsequent comparative analysis of statistical indicators. For a comparative assessment of the level of physical development and identification of significant differences between the two groups, the following index methods were used: body mass, Rohrer, Erisman, Pignet, Rees-Eysenck, Tanner. Results and discussion. Based on the results of the study, it was concluded that Penza residents of 1999–2004 birth, compared with predecessors, there was a significant increase in the studied absolute anthropometric parameters with a simultaneous shortening of the hand and shin length. Among the representatives of the modern youth of the region, when compared with the group of 1986– 1990 birth, the number of people with mesomorphy increased by 2.2 times, the number of people with overweight – by 1.5 times, the number of individuals with a narrow chest – by 1.3 times, the number of cases of a low degree of physical development, hypersthenic type (according to the results of calculating the Rees-Eysenck index) – by 1.2 times, at the same time the number of normosthenics increased by 1.1 times (according to the results of calculating the Pignet index). Conclusions. Comparative analysis showed significant changes in the constitution of the autochthons of Penza region of adolescents over 15 years.
{"title":"Changes in the morphological profile of adolescents in Penza and Penza region over 15 years","authors":"O. V. Kalmin, D. A. Lukyanenko","doi":"10.18699/ssmj20240310","DOIUrl":"https://doi.org/10.18699/ssmj20240310","url":null,"abstract":"Determining the physical development of the population of the regions is quite convenient within the framework of identifying the level of public health, while it is very important to track changes in the physical health of adolescents entering the reproductive phase of life, depending on the periods of development of the country. The aim of this study was to identify significant changes in the morphological profile of adolescents in Penza and Penza region over 15 years. Material and methods. The object of the study were 492 people of both sexes, 16 to 21 years of age, born and permanently residing in Penza and settlements of Penza region, divided into two groups according to the year of birth (group 1 – born in 1986–1990, 2 group – born in 1999–2004). Anthropometry and somatometry were carried out by the method of V.V. Bunak with subsequent comparative analysis of statistical indicators. For a comparative assessment of the level of physical development and identification of significant differences between the two groups, the following index methods were used: body mass, Rohrer, Erisman, Pignet, Rees-Eysenck, Tanner. Results and discussion. Based on the results of the study, it was concluded that Penza residents of 1999–2004 birth, compared with predecessors, there was a significant increase in the studied absolute anthropometric parameters with a simultaneous shortening of the hand and shin length. Among the representatives of the modern youth of the region, when compared with the group of 1986– 1990 birth, the number of people with mesomorphy increased by 2.2 times, the number of people with overweight – by 1.5 times, the number of individuals with a narrow chest – by 1.3 times, the number of cases of a low degree of physical development, hypersthenic type (according to the results of calculating the Rees-Eysenck index) – by 1.2 times, at the same time the number of normosthenics increased by 1.1 times (according to the results of calculating the Pignet index). Conclusions. Comparative analysis showed significant changes in the constitution of the autochthons of Penza region of adolescents over 15 years.","PeriodicalId":24058,"journal":{"name":"Сибирский научный медицинский журнал","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141680971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The aim of the study is to determine the morphometric features of splenic vasculature structural components (biounits, BU) of various kinds in individuals of different sex and age. Material and methods. The paper is based on the results of morphometric study of corrosion casts of splenic venous vasculature of 64 people (32 men, 32 women) at the age of 21 to 60 years (32 first period of adulthood, 32 second period of adulthood), deceased from sudden death and accidental causes. The study was conducted in compliance with ethical principles, including the World Medical Association’s Declaration of Helsinki. The diameters (D) and lengths (L) of the venous segments constituting BU were measured. Splenic venous vasculature was represented as a system consisting of three types of BU: 1 BU – the proximal segment diameter (D) is less than the sum of the diameters of distal segments (dmax and dmin) associated with it, D < dmax + dmin; 0 BU – D = dmax + dmin; 2 BU – D > dmax + dmin. Results. All three kinds of BUs were identified; there was a significant relationship between the relative number of BUs of different kinds, sex and age group; the sizes of all three kinds of BUs were determined; 1 BU was the largest and 0 BU was the smallest; 0 BU was the most symmetrical and 2 BU was the most asymmetrical; the relative number of 1 BU decreased, 0 BU increased, and 2 BU practically did not change in the direction from proximal to distal parts of the channel. BUs of the 1st kind have the largest diameter of proximal segments, while 2 BUs occupy the middle position in the range of values of the investigated parameters. The smallest diameter belongs to 0 BU. As for the length of segments L, the maximum values are typical for 1 BU, the minimum – for 2 BU, and the middle position in the series is occupied by 0 BU. Conclusions. The results obtained can serve as a foundation for the creation of a morphometric standard of splenic venous vasculature, and should be considered in its numerical modelling.
研究的目的是确定不同性别和年龄个体的各种脾脏血管结构成分（biounits，BU）的形态特征。材料和方法本文基于对 64 名 21 至 60 岁（32 名男性，32 名女性）因猝死和意外原因死亡者（32 名成年第一期，32 名成年第二期）的脾静脉血管腐蚀铸模进行形态计量学研究的结果。这项研究符合伦理原则，包括世界医学协会的《赫尔辛基宣言》。测量了构成 BU 的静脉段的直径（D）和长度（L）。脾静脉血管被表示为由三种类型的 BU 组成的系统：1 BU - 近端静脉段直径（D）小于与其相关的远端静脉段直径（dmax 和 dmin）之和，D < dmax + dmin；0 BU - D = dmax + dmin；2 BU - D > dmax + dmin。结果。确定了三种 BU 的大小：1 BU 最大，0 BU 最小；0 BU 最对称，2 BU 最不对称；1 BU 的相对数量从通道近端向远端方向减少，0 BU 的相对数量增加，2 BU 的相对数量几乎没有变化。第 1 种 BU 的近端直径最大，而第 2 种 BU 在调查参数值范围内处于中间位置。直径最小的是 0 BU。至于节段的长度 L，最大值通常为 1 BU，最小值为 2 BU，而 0 BU 则处于中间位置。结论所获得的结果可作为建立脾静脉血管形态计量标准的基础，并应在其数值建模中加以考虑。
{"title":"Morphometric features of the venous vasculature in spleen as a fractal system","authors":"A. S. Dadashev, I. Miltykh, O. Zenin, E. Kafarov","doi":"10.18699/ssmj20240308","DOIUrl":"https://doi.org/10.18699/ssmj20240308","url":null,"abstract":"The aim of the study is to determine the morphometric features of splenic vasculature structural components (biounits, BU) of various kinds in individuals of different sex and age. Material and methods. The paper is based on the results of morphometric study of corrosion casts of splenic venous vasculature of 64 people (32 men, 32 women) at the age of 21 to 60 years (32 first period of adulthood, 32 second period of adulthood), deceased from sudden death and accidental causes. The study was conducted in compliance with ethical principles, including the World Medical Association’s Declaration of Helsinki. The diameters (D) and lengths (L) of the venous segments constituting BU were measured. Splenic venous vasculature was represented as a system consisting of three types of BU: 1 BU – the proximal segment diameter (D) is less than the sum of the diameters of distal segments (dmax and dmin) associated with it, D < dmax + dmin; 0 BU – D = dmax + dmin; 2 BU – D > dmax + dmin. Results. All three kinds of BUs were identified; there was a significant relationship between the relative number of BUs of different kinds, sex and age group; the sizes of all three kinds of BUs were determined; 1 BU was the largest and 0 BU was the smallest; 0 BU was the most symmetrical and 2 BU was the most asymmetrical; the relative number of 1 BU decreased, 0 BU increased, and 2 BU practically did not change in the direction from proximal to distal parts of the channel. BUs of the 1st kind have the largest diameter of proximal segments, while 2 BUs occupy the middle position in the range of values of the investigated parameters. The smallest diameter belongs to 0 BU. As for the length of segments L, the maximum values are typical for 1 BU, the minimum – for 2 BU, and the middle position in the series is occupied by 0 BU. Conclusions. The results obtained can serve as a foundation for the creation of a morphometric standard of splenic venous vasculature, and should be considered in its numerical modelling.","PeriodicalId":24058,"journal":{"name":"Сибирский научный медицинский журнал","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141680954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Y. Kalinin, I. Suchkov, I. Shanaev, R. M. Khashumov, K. S. Pshennikova
Aim of the study was to evaluate the features of the anatomy of the deep vein of the femur according to CT-phlebography data. Material and methods. The data of CT-phlebography of 100 limbs of 50 patients (27 women, 23 men, mean age 39 years, age range 28–46 years) obtained in 2021–2023 were used as the basis of the work. The study was performed according to the original technique (patent of the Russian Federation N 2799023) on a 128-slice multispiral computed tomography scanner, with slice thickness of 0.5 mm, intravenous injection of contrast agent. The diameter of the femoral deep vein at different levels, the presence of additional trunks and its anastomoses with other segments of deep and superficial veins were evaluated. Results. True doubling of the femoral deep vein occurs with a frequency of 6 %, anastomoses of the femoral deep vein with the femoral-pubic segment of deep veins in 62 % cases. Variant anatomy with direct transition of the femoral or popliteal vein into the femoral deep vein occurs in 13 % of observations. Conclusions. The data on variant anatomy of the deep vein and its tributaries may be of practical importance when it is necessary to diagnose or choose the technique of surgical intervention in patients with venous diseases of the lower extremities.
{"title":"Study of variations in the anatomy of the deep femoral vein using indirect CT phlebography","authors":"R. Y. Kalinin, I. Suchkov, I. Shanaev, R. M. Khashumov, K. S. Pshennikova","doi":"10.18699/ssmj20240309","DOIUrl":"https://doi.org/10.18699/ssmj20240309","url":null,"abstract":"Aim of the study was to evaluate the features of the anatomy of the deep vein of the femur according to CT-phlebography data. Material and methods. The data of CT-phlebography of 100 limbs of 50 patients (27 women, 23 men, mean age 39 years, age range 28–46 years) obtained in 2021–2023 were used as the basis of the work. The study was performed according to the original technique (patent of the Russian Federation N 2799023) on a 128-slice multispiral computed tomography scanner, with slice thickness of 0.5 mm, intravenous injection of contrast agent. The diameter of the femoral deep vein at different levels, the presence of additional trunks and its anastomoses with other segments of deep and superficial veins were evaluated. Results. True doubling of the femoral deep vein occurs with a frequency of 6 %, anastomoses of the femoral deep vein with the femoral-pubic segment of deep veins in 62 % cases. Variant anatomy with direct transition of the femoral or popliteal vein into the femoral deep vein occurs in 13 % of observations. Conclusions. The data on variant anatomy of the deep vein and its tributaries may be of practical importance when it is necessary to diagnose or choose the technique of surgical intervention in patients with venous diseases of the lower extremities.","PeriodicalId":24058,"journal":{"name":"Сибирский научный медицинский журнал","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141684151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. A. Gaponov, I. D. Ufimtseva, E. G. Dmitrieva, D. K. Kuznetsov, V. Pryakhina, A. Iakimov
Normal anatomy of the left atrial appendage (LAA) of human fetus is of a great importance for fetal cardiac surgery and heart bioprinting. Aim of the study was to clarify the mesoscopic anatomy and histotopography of different parts of the LAA walls in normal human fetuses of 16–22 gestation weeks. Material and methods. We prepared serial histotopograms of the left atrial appendages from 10 normal human fetal hearts stained by Masson trichrome, orcein and fast green. We studied slides by means Olympus CX microscope, TOUPCAM U31S digital camera, and ADF-Image program for measuring. Using a Carl Zeiss EVO LS 10 scanning electron microscope at a magnification of 15–5000 times, three samples were examined using the freeze-chip method. Results. Having measured the outer walls of the LAA intertrabecular spaces, we found that at the level of the middle third of the left atrium, their thickness is minimal in the posterior wall (80 [61–97] μm) (median [lower quartile; upper quartile]), thickness in the anterior wall is 142.9 ± 33.2 μm (mean ± standard deviation) (101 [79–192] μm). At the level of the coronary sulcus, the same parameters were 143.7 ± 23.6 µm (147.5 [90–180] µm) and 137.4 ± 33.9 µm (101 [68–195] µm), respectively. Downward, LAA posterior wall increased about 1.8 in thickness, whereas the thickness of the anterior wall was the same. The endocardium showed the same thickness in all locations. Microanatomically, the LAA myocardium never discovered to build from distinct layers but “anatomical syncytium” or seldom bundles. Collagen and elastic layers were common for endocardium, rare for epicardium. Endocardial elastic fibers interweaved in the underlying collagen so the distinct boundary lacks there. Conclusions. Mesoscopic and microanatomical features of LAA walls in human fetus consist of variable thickness at different levels, unlayered but “syncytial” myocardium, muscleless areas, elastic and collagen layers of the endocardium.
{"title":"Mesoscopic anatomy and histotopography of the left atrial appendage walls in human fetal heart","authors":"A. A. Gaponov, I. D. Ufimtseva, E. G. Dmitrieva, D. K. Kuznetsov, V. Pryakhina, A. Iakimov","doi":"10.18699/ssmj20240307","DOIUrl":"https://doi.org/10.18699/ssmj20240307","url":null,"abstract":"Normal anatomy of the left atrial appendage (LAA) of human fetus is of a great importance for fetal cardiac surgery and heart bioprinting. Aim of the study was to clarify the mesoscopic anatomy and histotopography of different parts of the LAA walls in normal human fetuses of 16–22 gestation weeks. Material and methods. We prepared serial histotopograms of the left atrial appendages from 10 normal human fetal hearts stained by Masson trichrome, orcein and fast green. We studied slides by means Olympus CX microscope, TOUPCAM U31S digital camera, and ADF-Image program for measuring. Using a Carl Zeiss EVO LS 10 scanning electron microscope at a magnification of 15–5000 times, three samples were examined using the freeze-chip method. Results. Having measured the outer walls of the LAA intertrabecular spaces, we found that at the level of the middle third of the left atrium, their thickness is minimal in the posterior wall (80 [61–97] μm) (median [lower quartile; upper quartile]), thickness in the anterior wall is 142.9 ± 33.2 μm (mean ± standard deviation) (101 [79–192] μm). At the level of the coronary sulcus, the same parameters were 143.7 ± 23.6 µm (147.5 [90–180] µm) and 137.4 ± 33.9 µm (101 [68–195] µm), respectively. Downward, LAA posterior wall increased about 1.8 in thickness, whereas the thickness of the anterior wall was the same. The endocardium showed the same thickness in all locations. Microanatomically, the LAA myocardium never discovered to build from distinct layers but “anatomical syncytium” or seldom bundles. Collagen and elastic layers were common for endocardium, rare for epicardium. Endocardial elastic fibers interweaved in the underlying collagen so the distinct boundary lacks there. Conclusions. Mesoscopic and microanatomical features of LAA walls in human fetus consist of variable thickness at different levels, unlayered but “syncytial” myocardium, muscleless areas, elastic and collagen layers of the endocardium.","PeriodicalId":24058,"journal":{"name":"Сибирский научный медицинский журнал","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141682323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. V. Afonicheva, M. V. Smolnikova, M. Shubina, S. Tereshchenko
Adolescence is one of the most difficult period in the person’s life. Adolescent behavior is influenced by many factors, including the social environment, internal attitudes and hormonal levels. One of the important hormones that can change behavior is oxytocin – an extremely important prosocial neuropeptide that influences social bonding from an early age. The effect of oxytocin on the psycho-emotional state is quite individual and may depend on age, gender, ethnocultural factors, social environment, the presence of stress factors, and personality traits. The results of the studies indicate the relationship between the increased concentration of oxytocin and the presence of developed social contacts. The aim of this work was to identify an association between psychosocial characteristics in adolescent of different gender and rs53576 polymorphism of the oxytocin receptor gene. Material and methods. Psychological and genetic testing of adolescents aged 11–18 living in the territory of the Angara-Yenisei macroregion was carried out. Mental health assessment was carried out using the Russian version of the questionnaire “Strengths and difficulties” by R. Goodman. Results and discussion. The rs53576 OXTR AA genotype is more frequent in boys than in girls (20.8 % vs. 14.3 %, p = 0.03). The association of the rs53576 OXTR A allele with social behavior disorders and depression was previously shown. Boys carrying the AA genotype have significantly higher scores (borderline values) on the scales of “Emotional symptoms” and “Problems communicating with peers” compared with carriers of the GA and GG genotypes. Conclusions. Evidences of differing individual psychosocial consequences of high activity of the oxytocinergic system, depending on the context of the social environment, allowed us to formulate the “hypothesis of the social significance of oxytocin”. Problems in communication with peers in adolescents with pronounced social empathy and altruistic personal characteristics can be successfully overcome. Both the general orientation of the pedagogical process towards the approval of prosocial behavior, and socially significant personalities, whom adolescents can perceive as an example to follow, can help in many ways.
青春期是人一生中最艰难的时期之一。青少年的行为受到很多因素的影响，包括社会环境、内在态度和荷尔蒙水平。催产素是能改变行为的重要荷尔蒙之一，它是一种极其重要的亲社会神经肽，从小就影响着社会关系。催产素对心理情感状态的影响是因人而异的，可能取决于年龄、性别、民族文化因素、社会环境、压力因素的存在以及个性特征。研究结果表明，催产素浓度的增加与发达的社会交往之间存在关系。本研究旨在确定不同性别青少年的社会心理特征与催产素受体基因 rs53576 多态性之间的关系。材料和方法对居住在安加拉-叶尼塞大区的 11-18 岁青少年进行了心理和基因测试。使用 R. Goodman 的俄文版 "优势与困难 "问卷进行了心理健康评估。结果与讨论rs53576 OXTR AA 基因型在男孩中的出现率高于女孩（20.8% 对 14.3%，p = 0.03）。rs53576 OXTR A 等位基因与社会行为障碍和抑郁症的关系此前已被证实。与 GA 和 GG 基因型携带者相比，携带 AA 基因型的男孩在 "情绪症状 "和 "与同伴沟通问题 "量表上的得分（边缘值）明显更高。结论有证据表明，催产素能系统的高活性会因社会环境的不同而导致不同的个体社会心理后果，因此我们提出了 "催产素的社会意义假说"。具有明显社会移情和利他主义个性特征的青少年在与同伴交流时遇到的问题是可以成功克服的。教学过程中对亲社会行为的普遍认可，以及具有社会意义的人物（青少年可以将其视为学习的榜样），都可以在许多方面起到帮助作用。
{"title":"Polymorphic variants of the oxytocin receptor gene (OXTR rs53576) and psychosocial characteristics in adolescent","authors":"K. V. Afonicheva, M. V. Smolnikova, M. Shubina, S. Tereshchenko","doi":"10.18699/ssmj20240311","DOIUrl":"https://doi.org/10.18699/ssmj20240311","url":null,"abstract":"Adolescence is one of the most difficult period in the person’s life. Adolescent behavior is influenced by many factors, including the social environment, internal attitudes and hormonal levels. One of the important hormones that can change behavior is oxytocin – an extremely important prosocial neuropeptide that influences social bonding from an early age. The effect of oxytocin on the psycho-emotional state is quite individual and may depend on age, gender, ethnocultural factors, social environment, the presence of stress factors, and personality traits. The results of the studies indicate the relationship between the increased concentration of oxytocin and the presence of developed social contacts. The aim of this work was to identify an association between psychosocial characteristics in adolescent of different gender and rs53576 polymorphism of the oxytocin receptor gene. Material and methods. Psychological and genetic testing of adolescents aged 11–18 living in the territory of the Angara-Yenisei macroregion was carried out. Mental health assessment was carried out using the Russian version of the questionnaire “Strengths and difficulties” by R. Goodman. Results and discussion. The rs53576 OXTR AA genotype is more frequent in boys than in girls (20.8 % vs. 14.3 %, p = 0.03). The association of the rs53576 OXTR A allele with social behavior disorders and depression was previously shown. Boys carrying the AA genotype have significantly higher scores (borderline values) on the scales of “Emotional symptoms” and “Problems communicating with peers” compared with carriers of the GA and GG genotypes. Conclusions. Evidences of differing individual psychosocial consequences of high activity of the oxytocinergic system, depending on the context of the social environment, allowed us to formulate the “hypothesis of the social significance of oxytocin”. Problems in communication with peers in adolescents with pronounced social empathy and altruistic personal characteristics can be successfully overcome. Both the general orientation of the pedagogical process towards the approval of prosocial behavior, and socially significant personalities, whom adolescents can perceive as an example to follow, can help in many ways.","PeriodicalId":24058,"journal":{"name":"Сибирский научный медицинский журнал","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141680586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Endometriosis is one of the most common and understudied diseases in women all over the world. The more than a century-old history of endometriosis research does not currently provide unambiguous answers about the causes, risk factors, etiology and methods of its treatment. Chronic pelvic pain as one of the main symptoms of endometriosis is the cause of not only physical suffering, but also a negative change in the mental status of women, deterioration of their quality of life. Body-oriented methods of treating the disease often turn out to be ineffective. The relationship between psychosomatic components (depression, anxiety, neuroticism) and chronic pelvic pain, despite the evidence, remains underestimated and is not always considered in medical theory and practice. This review article reflects the main epidemiological characteristics of chronic pain syndrome in genital endometriosis in women, from an epidemiological point of view, the main approaches of modern medical science to determining risk factors for its occurrence and development are considered. The promising role of an interdisciplinary (biopsychosocial) approach in the diagnosis and treatment of such patients, the need for further research and practical application of complex methods of treatment of chronic pain syndrome in genital endometriosis are shown.
{"title":"Epidemiological aspects of chronic pelvic pain syndrome in genital endometriosis (review article)","authors":"E. V. Zhigalova, A. I. Fedorova, B. Aslanov","doi":"10.18699/ssmj20240301","DOIUrl":"https://doi.org/10.18699/ssmj20240301","url":null,"abstract":"Endometriosis is one of the most common and understudied diseases in women all over the world. The more than a century-old history of endometriosis research does not currently provide unambiguous answers about the causes, risk factors, etiology and methods of its treatment. Chronic pelvic pain as one of the main symptoms of endometriosis is the cause of not only physical suffering, but also a negative change in the mental status of women, deterioration of their quality of life. Body-oriented methods of treating the disease often turn out to be ineffective. The relationship between psychosomatic components (depression, anxiety, neuroticism) and chronic pelvic pain, despite the evidence, remains underestimated and is not always considered in medical theory and practice. This review article reflects the main epidemiological characteristics of chronic pain syndrome in genital endometriosis in women, from an epidemiological point of view, the main approaches of modern medical science to determining risk factors for its occurrence and development are considered. The promising role of an interdisciplinary (biopsychosocial) approach in the diagnosis and treatment of such patients, the need for further research and practical application of complex methods of treatment of chronic pain syndrome in genital endometriosis are shown.","PeriodicalId":24058,"journal":{"name":"Сибирский научный медицинский журнал","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141682270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The surgical anatomy of the dorsal pancreatic artery is of paramount importance in the work of a pancreatic surgeon, transplant surgeon, and oncologist. This artery supplies blood to the pancreatic neck region, the area where, in the vast majority of cases, pancreatodigestive anastomosis is performed. Material and methods. A systematic literature review was conducted using the PubMed, Embase, CyberLeninka, and GoogleScholar bibliographic databases. The following keywords and their combinations were used: «cranial trunk», «superior mesenteric artery», «splenic artery», «common hepatic artery», «dorsal pancreatic artery», «pancreatic body and tail arteries», «pancreatic isthmus blood supply», «pancreatic anatomical segment arteries», «anatomy», «variants», «arterial anastomoses» and «anomalies». Results and discussion. Frequency of dorsal pancreatic artery was 79–100 % according to the data of anatomical investigations; radiological ones – 64.4–100 %. Its main sources were the splenic artery – from 22.22 to 80 % according to anatomists, from 13.5 to 100 % according to radiologists; the cranial trunk – 3–33.3 and 8–27.75 % respectively; the superior mesenteric artery – 1.8–25 and 3.8 % respectively; the common hepatic artery – 12–24 % regardless of the research methods. The course of the dorsal pancreatic artery and its division into the terminal branches (prepancreatic and inferior pancreatic arteries) was characterized by relative constancy. Conclusions. This review summarizes world literature data devoted to the topographic anatomy of the splenic artery and its pancreatic branches involved in the blood supply of the body and tail of the pancreas. The search for dorsal pancreatic artery in anatomical and radiological material should start from the main trunk and the area of its division into terminal branches, and then move to its source.
{"title":"Dorsal pancreatic artery: incidence, morphometry, origin, course, branches","authors":"N. Pronin","doi":"10.18699/ssmj20240303","DOIUrl":"https://doi.org/10.18699/ssmj20240303","url":null,"abstract":"The surgical anatomy of the dorsal pancreatic artery is of paramount importance in the work of a pancreatic surgeon, transplant surgeon, and oncologist. This artery supplies blood to the pancreatic neck region, the area where, in the vast majority of cases, pancreatodigestive anastomosis is performed. Material and methods. A systematic literature review was conducted using the PubMed, Embase, CyberLeninka, and GoogleScholar bibliographic databases. The following keywords and their combinations were used: «cranial trunk», «superior mesenteric artery», «splenic artery», «common hepatic artery», «dorsal pancreatic artery», «pancreatic body and tail arteries», «pancreatic isthmus blood supply», «pancreatic anatomical segment arteries», «anatomy», «variants», «arterial anastomoses» and «anomalies». Results and discussion. Frequency of dorsal pancreatic artery was 79–100 % according to the data of anatomical investigations; radiological ones – 64.4–100 %. Its main sources were the splenic artery – from 22.22 to 80 % according to anatomists, from 13.5 to 100 % according to radiologists; the cranial trunk – 3–33.3 and 8–27.75 % respectively; the superior mesenteric artery – 1.8–25 and 3.8 % respectively; the common hepatic artery – 12–24 % regardless of the research methods. The course of the dorsal pancreatic artery and its division into the terminal branches (prepancreatic and inferior pancreatic arteries) was characterized by relative constancy. Conclusions. This review summarizes world literature data devoted to the topographic anatomy of the splenic artery and its pancreatic branches involved in the blood supply of the body and tail of the pancreas. The search for dorsal pancreatic artery in anatomical and radiological material should start from the main trunk and the area of its division into terminal branches, and then move to its source.","PeriodicalId":24058,"journal":{"name":"Сибирский научный медицинский журнал","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141683071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Quantitative characteristics of the impact of factors of the production environment (physical, chemical, biological), the severity and intensity of the labor process, their contribution to the deterioration of the health of the working contingent and the development of mechanisms of premature aging can hardly be overestimated. Occupational factors play a leading role among the health risk factors of the labor contingent in the workplace. Their effect on the organism of people engaged in work with harmful and (or) dangerous working conditions can have cumulative effect on the health of workers and cause premature aging of the body, exert an adverse effect on the central nervous, cardiovascular, endocrine, reproductive, digestive, excretory, blood, musculoskeletal system, causing psychosomatic, acute and chronic occupational diseases, and poisoning. Long-term chronic “occupational” and domestic stress prevails among the mechanisms that reveal premature aging at the level of the hypothalamic-pituitary-adrenal axis. The article analyzes (according to literature sources) the most probable risk factors and mechanisms that trigger the processes of premature aging.
{"title":"On occupational factors and premature aging (literature review)","authors":"O. A. Savchenko, I. I. Novikova, O. Plotnikova","doi":"10.18699/ssmj20240304","DOIUrl":"https://doi.org/10.18699/ssmj20240304","url":null,"abstract":"Quantitative characteristics of the impact of factors of the production environment (physical, chemical, biological), the severity and intensity of the labor process, their contribution to the deterioration of the health of the working contingent and the development of mechanisms of premature aging can hardly be overestimated. Occupational factors play a leading role among the health risk factors of the labor contingent in the workplace. Their effect on the organism of people engaged in work with harmful and (or) dangerous working conditions can have cumulative effect on the health of workers and cause premature aging of the body, exert an adverse effect on the central nervous, cardiovascular, endocrine, reproductive, digestive, excretory, blood, musculoskeletal system, causing psychosomatic, acute and chronic occupational diseases, and poisoning. Long-term chronic “occupational” and domestic stress prevails among the mechanisms that reveal premature aging at the level of the hypothalamic-pituitary-adrenal axis. The article analyzes (according to literature sources) the most probable risk factors and mechanisms that trigger the processes of premature aging.","PeriodicalId":24058,"journal":{"name":"Сибирский научный медицинский журнал","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141681416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Sulima, D. Kondratyuk, T. Babich, Ye. I. Nikolaeva
Often premature birth is accompanied by preterm premature rupture of membranes (PPROM). PPROM is a complication of the course of pregnancy in 2–3 % cases and is the most common in premature birth. As a rule, the protocols for the management of such patients vary greatly and are mainly individual. In practical obstetrics, there is an urgent need to decide whether the risk of complications resulting from previous PPROM exceeds the risk of intrauterine infection. Of course, the need for further research in this area is necessary, which will help to choose the tactics of the maximum allowable period that would be optimal for reducing perinatal morbidity and mortality, as well as to identify factors that improve the prognosis for the mother and fetus. The review analyzes and summarizes the results of studies on PRPO in premature pregnancy complicated by chorioamnionitis. The advantages and disadvantages of various approaches in the management of such patients are considered. The modern medical literature presented in eLibrary and CyberLeninka electronic libraries, PubMed database of medical and biological publications has been studied.
{"title":"The problem of preterm rupture of fetal membranes in premature pregnancy complicated by chorioamnionitis","authors":"A. Sulima, D. Kondratyuk, T. Babich, Ye. I. Nikolaeva","doi":"10.18699/ssmj20240305","DOIUrl":"https://doi.org/10.18699/ssmj20240305","url":null,"abstract":"Often premature birth is accompanied by preterm premature rupture of membranes (PPROM). PPROM is a complication of the course of pregnancy in 2–3 % cases and is the most common in premature birth. As a rule, the protocols for the management of such patients vary greatly and are mainly individual. In practical obstetrics, there is an urgent need to decide whether the risk of complications resulting from previous PPROM exceeds the risk of intrauterine infection. Of course, the need for further research in this area is necessary, which will help to choose the tactics of the maximum allowable period that would be optimal for reducing perinatal morbidity and mortality, as well as to identify factors that improve the prognosis for the mother and fetus. The review analyzes and summarizes the results of studies on PRPO in premature pregnancy complicated by chorioamnionitis. The advantages and disadvantages of various approaches in the management of such patients are considered. The modern medical literature presented in eLibrary and CyberLeninka electronic libraries, PubMed database of medical and biological publications has been studied.","PeriodicalId":24058,"journal":{"name":"Сибирский научный медицинский журнал","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141682580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. I. Ryazantsev, E. K. Grebennikov, I. N. Grebennikova, O. Sorokin, M. Subotyalov
The aim of study was to investigate the indicators of cardiovascular and autonomic adaptation of cadets of the Institute of Civil Aviation to different types of locomotor motion activity. Material and methods. Heart rate, blood pressure, cardiovascular indices were assessed in 96 healthy cadets divided into four groups according to the type of their locomotor motion activity. The study also analyzed Baevsky’s indices. Results and its discussion. The analysis of cardiovascular indicators and indicators of heart rate variability both in the background state and in response to an active orthostatic test revealed an increase in the adaptive reserve and heart rate variability in the series «not engaged» – «self-exercising» – «game sports» – «cyclical sports». It has been established that cadets involved in cyclic sports have greater parasympathetic activity and its influence on the heart rate both at rest and in response to orthostatic load, which reflects a deeper degree of their adaptation to physical and educational load, based on structural changes in cells of the cardiovascular, nervous and endocrine systems. Apparently, the data obtained indicate the manifestation of a general strategy of structural and functional restructuring of the body’s regulatory systems, aimed at the formation of optimal compensatory and adaptive changes in hemodynamics.
{"title":"Cardiovascular and vegetative adaptation of the body of cadets of the Institute of Civil Aviation to different types of locomotor motion activity","authors":"A. I. Ryazantsev, E. K. Grebennikov, I. N. Grebennikova, O. Sorokin, M. Subotyalov","doi":"10.18699/ssmj20240312","DOIUrl":"https://doi.org/10.18699/ssmj20240312","url":null,"abstract":"The aim of study was to investigate the indicators of cardiovascular and autonomic adaptation of cadets of the Institute of Civil Aviation to different types of locomotor motion activity. Material and methods. Heart rate, blood pressure, cardiovascular indices were assessed in 96 healthy cadets divided into four groups according to the type of their locomotor motion activity. The study also analyzed Baevsky’s indices. Results and its discussion. The analysis of cardiovascular indicators and indicators of heart rate variability both in the background state and in response to an active orthostatic test revealed an increase in the adaptive reserve and heart rate variability in the series «not engaged» – «self-exercising» – «game sports» – «cyclical sports». It has been established that cadets involved in cyclic sports have greater parasympathetic activity and its influence on the heart rate both at rest and in response to orthostatic load, which reflects a deeper degree of their adaptation to physical and educational load, based on structural changes in cells of the cardiovascular, nervous and endocrine systems. Apparently, the data obtained indicate the manifestation of a general strategy of structural and functional restructuring of the body’s regulatory systems, aimed at the formation of optimal compensatory and adaptive changes in hemodynamics.","PeriodicalId":24058,"journal":{"name":"Сибирский научный медицинский журнал","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141683406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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