Pub Date : 2016-10-28DOI: 10.4172/2165-7904.C1.029
M. Lemstra
{"title":"Weight-loss intervention adherence levels and factors promoting adherence","authors":"M. Lemstra","doi":"10.4172/2165-7904.C1.029","DOIUrl":"https://doi.org/10.4172/2165-7904.C1.029","url":null,"abstract":"","PeriodicalId":243288,"journal":{"name":"Journal of obesity and weight loss therapy","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120956895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-10-27DOI: 10.4172/2165-7904.1000322
Marko Hingi, John Ngonyani, Hyasinta Jaka
Background: Overweight and obesity is public health issue which is growing among young generation worldwide. 15-50% of the people living in urban areas in Africa have obesity or overweight, and it is projected that by year 2012, about 75% of people will be in developing countries. Objective: To determine the prevalence and related factors of overweight and obesity among high level secondary school adolescent in Mwanza Tanzania. Methodology: A cross-sectional study conducted among 381 high school adolescents in Nyamagana, Mwanza in October 2014. Obesity and overweight were measured using height and weight of each student. The demographic, social and nutritional history; life style information and pattern of dietary intake were interviewed verbally. Result: The overall prevalence of obesity and overweight were 2.6% and 14.2% respectively. The prevalence of (0.8% overweight, 0% obese) in adolescents those residing out of school campus was lower than overweight (13.4%) and obesity (2.6%) residing in boarding school. The meal frequency, fruits, meat, and vegetables consumption were statistically significant with the p value of P<0.05. Conclusion: adolescent’s obesity and overweight are emerging health problem we need to plan and implement effective preventive strategies to stop this epidemic.
{"title":"Overweight and Obesity among High Level Secondary School Adolescents inMwanza Tanzania","authors":"Marko Hingi, John Ngonyani, Hyasinta Jaka","doi":"10.4172/2165-7904.1000322","DOIUrl":"https://doi.org/10.4172/2165-7904.1000322","url":null,"abstract":"Background: Overweight and obesity is public health issue which is growing among young generation worldwide. 15-50% of the people living in urban areas in Africa have obesity or overweight, and it is projected that by year 2012, about 75% of people will be in developing countries. Objective: To determine the prevalence and related factors of overweight and obesity among high level secondary school adolescent in Mwanza Tanzania. Methodology: A cross-sectional study conducted among 381 high school adolescents in Nyamagana, Mwanza in October 2014. Obesity and overweight were measured using height and weight of each student. The demographic, social and nutritional history; life style information and pattern of dietary intake were interviewed verbally. Result: The overall prevalence of obesity and overweight were 2.6% and 14.2% respectively. The prevalence of (0.8% overweight, 0% obese) in adolescents those residing out of school campus was lower than overweight (13.4%) and obesity (2.6%) residing in boarding school. The meal frequency, fruits, meat, and vegetables consumption were statistically significant with the p value of P<0.05. Conclusion: adolescent’s obesity and overweight are emerging health problem we need to plan and implement effective preventive strategies to stop this epidemic.","PeriodicalId":243288,"journal":{"name":"Journal of obesity and weight loss therapy","volume":"135 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132691770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-10-26DOI: 10.4172/2165-7904.1000321
A. Kh, Z. Eugène, B. Hounkpatin, T. Véronique, Mewanou Serge, T. Blaise, Chobli Martin
Introduction: The morbidity townships of the obesity at the women are the complications of pregnancy, the dystocia, and the childbirths by caesarian procedure. This survey had for objective to determine the frequency of the obesity at the parturient, to value the impact of the obesity on the childbirth by caesarean and the complications postoperative immediate in the teaching hospitals of Cotonou. Patients and method: We did a prospective, comparative and analytic survey of January 13 to April 13, 2012. Eight hundred ninety-one consecutive parturient having had a Caesarean was include. We studied the anesthetic techniques, the techniques of control of the aerial ways, the number of necessary tests for the tracheal intubation, the complications and aftercare of the first 48 hours. A comparison has been made according to the BMI. The obesity has been defined by a BMI ≥ 30 kg/m2. The parturient has been classified in two groups: Non obese: BMI ≤ 30 kg/m2, obese: BMI ≥ 30. Results: The obesity has been recovered at 286 parturient is 32.10%. There were 703 (78.90%) Caesareans in emergency and 188 (21.09%) programmed Caesareans. The obese parturient also required more frequently several lumbar punctures (p<0.001) at the time of the spinal anesthesia and more of conversion of the spinal anesthesia into an anesthesia general (p=0.008). The postoperative complications: laryngeal pain, back pain and suppuration of the wound were more frequent at the obese parturient. Conclusion: The obesity is frequent at the parturient in Benin. The post-operative complications are more frequent after the Caesarean at the obese parturient.
{"title":"Obesity: Anesthetic and Caesarean Procedure Complications in the TeachingCenters of Cotonou","authors":"A. Kh, Z. Eugène, B. Hounkpatin, T. Véronique, Mewanou Serge, T. Blaise, Chobli Martin","doi":"10.4172/2165-7904.1000321","DOIUrl":"https://doi.org/10.4172/2165-7904.1000321","url":null,"abstract":"Introduction: The morbidity townships of the obesity at the women are the complications of pregnancy, the dystocia, and the childbirths by caesarian procedure. This survey had for objective to determine the frequency of the obesity at the parturient, to value the impact of the obesity on the childbirth by caesarean and the complications postoperative immediate in the teaching hospitals of Cotonou. Patients and method: We did a prospective, comparative and analytic survey of January 13 to April 13, 2012. Eight hundred ninety-one consecutive parturient having had a Caesarean was include. We studied the anesthetic techniques, the techniques of control of the aerial ways, the number of necessary tests for the tracheal intubation, the complications and aftercare of the first 48 hours. A comparison has been made according to the BMI. The obesity has been defined by a BMI ≥ 30 kg/m2. The parturient has been classified in two groups: Non obese: BMI ≤ 30 kg/m2, obese: BMI ≥ 30. Results: The obesity has been recovered at 286 parturient is 32.10%. There were 703 (78.90%) Caesareans in emergency and 188 (21.09%) programmed Caesareans. The obese parturient also required more frequently several lumbar punctures (p<0.001) at the time of the spinal anesthesia and more of conversion of the spinal anesthesia into an anesthesia general (p=0.008). The postoperative complications: laryngeal pain, back pain and suppuration of the wound were more frequent at the obese parturient. Conclusion: The obesity is frequent at the parturient in Benin. The post-operative complications are more frequent after the Caesarean at the obese parturient.","PeriodicalId":243288,"journal":{"name":"Journal of obesity and weight loss therapy","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123823770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-09-29DOI: 10.4172/2165-7904.1000318
A. Herrejón, I. Inchaurraga, J. Palop
Objective: To describe the respiratory functional alterations that occur in patients with morbid obesity (MO) and the possible influence of gender and distribution of body fat, measured as an index waist/hip ratio (wai/hip). Method: Prospective study in 2 years of anthropometric and functional parameters breathing in MO, determining age, body mass index (BMI), waist, hip, wai/hip index, blood gas values, flow-volume curve, plethysmography, diffusion of CO and maximum inspiratory (MIP) and expiratory (PEM) pressures. The results between men and women and the relationship between respiratory parameters and wai/hip index are compared. Results: We studied 171 patients, 80 men and 91 women, with 44 ± 12 years, weighing 130 ± 22 kg, with BMI of 48 ± 6 Kg/m2 and wai/hip index of 0.989-0.097 ± 48. There is a decrease in lung function parameters in the MO, showing men MIP worse, but better MEP, than women. Hypoxemia is common (55%), related to an older and worse flows and static volumes. Hypercapnia is 15% more common in men, and is related to the decrease in expiratory flows and increased residual volume. Wai/hip index does not correlate with respiratory parameters in the MO. Conclusions: Morbid obesity affects respiratory blood gas and has functional alterations. There are differences between men and women in the presence of hypercapnia and maximal respiratory pressures, without influencing the type of obesity messured with the wai/hip index.
目的:描述病态肥胖(MO)患者发生的呼吸功能改变，以及性别和体脂分布(以腰臀比指数(wai/hip)衡量)可能的影响。方法:前瞻性研究MO 2年的人体测量和功能参数，测定年龄、体重指数(BMI)、腰围、臀围/臀围指数、血气值、流量-体积曲线、体积脉搏图、CO弥散和最大吸气(MIP)和呼气(PEM)压力。比较了男性和女性的结果以及呼吸参数与wai/hip指数的关系。结果:171例患者，男80例，女91例，年龄44±12岁，体重130±22 kg, BMI 48±6 kg /m2, wai/hip指数0.989 ~ 0.097±48。MO的肺功能参数下降，显示男性MIP比女性更差，但MEP更好。低氧血症是常见的(55%)，与较旧和较差的血流和静态容量有关。高碳酸血症在男性中更常见15%，与呼气流量减少和残余容量增加有关。Wai/hip指数与MO的呼吸参数无关。结论:病态肥胖影响呼吸血气并具有功能改变。男性和女性在高碳酸血症和最大呼吸压力方面存在差异，但不影响wai/hip指数测量的肥胖类型。
{"title":"Pulmonary Function in Morbid Obesity: Influence of Sex and Body Distribution","authors":"A. Herrejón, I. Inchaurraga, J. Palop","doi":"10.4172/2165-7904.1000318","DOIUrl":"https://doi.org/10.4172/2165-7904.1000318","url":null,"abstract":"Objective: To describe the respiratory functional alterations that occur in patients with morbid obesity (MO) and the possible influence of gender and distribution of body fat, measured as an index waist/hip ratio (wai/hip). Method: Prospective study in 2 years of anthropometric and functional parameters breathing in MO, determining age, body mass index (BMI), waist, hip, wai/hip index, blood gas values, flow-volume curve, plethysmography, diffusion of CO and maximum inspiratory (MIP) and expiratory (PEM) pressures. The results between men and women and the relationship between respiratory parameters and wai/hip index are compared. Results: We studied 171 patients, 80 men and 91 women, with 44 ± 12 years, weighing 130 ± 22 kg, with BMI of 48 ± 6 Kg/m2 and wai/hip index of 0.989-0.097 ± 48. There is a decrease in lung function parameters in the MO, showing men MIP worse, but better MEP, than women. Hypoxemia is common (55%), related to an older and worse flows and static volumes. Hypercapnia is 15% more common in men, and is related to the decrease in expiratory flows and increased residual volume. Wai/hip index does not correlate with respiratory parameters in the MO. Conclusions: Morbid obesity affects respiratory blood gas and has functional alterations. There are differences between men and women in the presence of hypercapnia and maximal respiratory pressures, without influencing the type of obesity messured with the wai/hip index.","PeriodicalId":243288,"journal":{"name":"Journal of obesity and weight loss therapy","volume":"142 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127321330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-09-26DOI: 10.4172/2165-7904.1000320
A. G. Alkushi, Naser A. ElSawy, M. HijaziM, Eslam A. Header, Hataba Aa
Obesity can adversely affect overall health, leading to reduced life expectancy and/or an increase in the number of health problems. Meanwhile, alterations in testicular metabolism induced by high-energy diets (HED) may induce mitochondrial dysfunction, which is closely associated to reactive oxygen species (ROS) and oxidative stress. Reactive oxygen species (ROS)-mediated damage to sperm is a significant contributing pathology in 30–80% of infertility cases. Vitamin E is considered to be the most effective liposolouble antioxidant found in biological systems. Here we evaluated the protective role of vitamin E against obesity-induced morphological changes in testes from albino rats fed different diets. Animals were divided into four groups: Group 1: standard controlled diet (SCD); Group 2: positive control group fed a high-fat diet (HFD); Group 3: αTF+HFD fed HFD supplemented with 100 mg/kg vitamin E (αTF); Group 4: αTF+SCD, fed 100 mg/kg αTF and SCD. Rats were weighed before and after the 10 week feeding period to determine changes in body weight (BWG %). After collecting blood from an intracardiac puncture under deep anesthesia, all animals were sacrificed and samples were analyzed by light microscopy. A HFD appeared to cause spermatocyte and Leydig cell damage, as well as decreases in testicular weight and function and testosterone production. Vitamin E supplementation promoted Leydig cell repair and reduced damage induced by a HFD, suggesting that vitamin E is an important dietary component to mitigate the negative effects of a high fat diet.
{"title":"Therapeutic Effect of Vitamin E on Testicular Tissue Damage Caused by Obesity","authors":"A. G. Alkushi, Naser A. ElSawy, M. HijaziM, Eslam A. Header, Hataba Aa","doi":"10.4172/2165-7904.1000320","DOIUrl":"https://doi.org/10.4172/2165-7904.1000320","url":null,"abstract":"Obesity can adversely affect overall health, leading to reduced life expectancy and/or an increase in the number of health problems. Meanwhile, alterations in testicular metabolism induced by high-energy diets (HED) may induce mitochondrial dysfunction, which is closely associated to reactive oxygen species (ROS) and oxidative stress. Reactive oxygen species (ROS)-mediated damage to sperm is a significant contributing pathology in 30–80% of infertility cases. Vitamin E is considered to be the most effective liposolouble antioxidant found in biological systems. Here we evaluated the protective role of vitamin E against obesity-induced morphological changes in testes from albino rats fed different diets. Animals were divided into four groups: Group 1: standard controlled diet (SCD); Group 2: positive control group fed a high-fat diet (HFD); Group 3: αTF+HFD fed HFD supplemented with 100 mg/kg vitamin E (αTF); Group 4: αTF+SCD, fed 100 mg/kg αTF and SCD. Rats were weighed before and after the 10 week feeding period to determine changes in body weight (BWG %). After collecting blood from an intracardiac puncture under deep anesthesia, all animals were sacrificed and samples were analyzed by light microscopy. A HFD appeared to cause spermatocyte and Leydig cell damage, as well as decreases in testicular weight and function and testosterone production. Vitamin E supplementation promoted Leydig cell repair and reduced damage induced by a HFD, suggesting that vitamin E is an important dietary component to mitigate the negative effects of a high fat diet.","PeriodicalId":243288,"journal":{"name":"Journal of obesity and weight loss therapy","volume":"133 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122976741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-09-16DOI: 10.4172/2165-7904.C1.034
Lisha He Linhua Zhao Han Wang, Xiaolin Tong
{"title":"lncRNA expression signatures in response to tiaozhi jiangtang formula in type 2 diabetes mellitus (T2DM) with obesity and hyperlipidemia","authors":"Lisha He Linhua Zhao Han Wang, Xiaolin Tong","doi":"10.4172/2165-7904.C1.034","DOIUrl":"https://doi.org/10.4172/2165-7904.C1.034","url":null,"abstract":"","PeriodicalId":243288,"journal":{"name":"Journal of obesity and weight loss therapy","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114552174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-09-16DOI: 10.4172/2165-7904.C1.032
G. Leisman
{"title":"Is obesity a brain disease","authors":"G. Leisman","doi":"10.4172/2165-7904.C1.032","DOIUrl":"https://doi.org/10.4172/2165-7904.C1.032","url":null,"abstract":"","PeriodicalId":243288,"journal":{"name":"Journal of obesity and weight loss therapy","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125665696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-08-30DOI: 10.4172/2165-7904.C1.026
S. Kumagai
{"title":"Dietary obesity-resistance and muscle oxidative enzyme activities of the fast-twitch fiber dominant rat","authors":"S. Kumagai","doi":"10.4172/2165-7904.C1.026","DOIUrl":"https://doi.org/10.4172/2165-7904.C1.026","url":null,"abstract":"","PeriodicalId":243288,"journal":{"name":"Journal of obesity and weight loss therapy","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115989159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-08-25DOI: 10.4172/2165-7904.1000317
Ooi Tong Li, H. Oo, Lucy Kong Rn, A. Cheng, K. Ngiam
Background: Obesity is a global health problem. Laparoscopic Adjustable Gastric Banding (LAGB) is a type of bariatric surgery that is effective for weight loss and control of co-morbidities. Long-term results of LAGB in different obesity groups have been widely studied in Western populations but not in a multi-racial Asian population such as in Singapore. This paper aims to compare the outcomes of LAGB and describe its complications in obese Singaporean patients with Body Mass Index (BMI) 0.05). At the end of five years follow-up, Group A achieved 18.8%WL and 52.6% EWL while Group B achieved 18.7% WL and 34.9% EWL. In both groups, peak %WL was attained at 3 to 4 year follow-up before it tapered. A total of 90 patients (25%) developed complications during the study, with seven mortalities on follow-up, out of which two were band-related. Conclusion: LAGB is an effective bariatric surgical option for weight loss in obese Singaporean patients over a short-term but it is more beneficial for patients with BMI <40 kg/m2.
{"title":"Laparoscopic Adjustable Gastric Banding is more Effective in Body Mass Index<40 Kg/m2 for Short Term Weight Loss","authors":"Ooi Tong Li, H. Oo, Lucy Kong Rn, A. Cheng, K. Ngiam","doi":"10.4172/2165-7904.1000317","DOIUrl":"https://doi.org/10.4172/2165-7904.1000317","url":null,"abstract":"Background: Obesity is a global health problem. Laparoscopic Adjustable Gastric Banding (LAGB) is a type of bariatric surgery that is effective for weight loss and control of co-morbidities. Long-term results of LAGB in different obesity groups have been widely studied in Western populations but not in a multi-racial Asian population such as in Singapore. This paper aims to compare the outcomes of LAGB and describe its complications in obese Singaporean patients with Body Mass Index (BMI) 0.05). At the end of five years follow-up, Group A achieved 18.8%WL and 52.6% EWL while Group B achieved 18.7% WL and 34.9% EWL. In both groups, peak %WL was attained at 3 to 4 year follow-up before it tapered. A total of 90 patients (25%) developed complications during the study, with seven mortalities on follow-up, out of which two were band-related. Conclusion: LAGB is an effective bariatric surgical option for weight loss in obese Singaporean patients over a short-term but it is more beneficial for patients with BMI <40 kg/m2.","PeriodicalId":243288,"journal":{"name":"Journal of obesity and weight loss therapy","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126962479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-07-30DOI: 10.4172/2165-7904.1000312
I. Longhi
Recent data regarding Trans Fatty Acids (TFAs) have implicated this lipid as being particularly deleterious to human health. TFAs are unsaturated fatty acids that contain at least one non conjugated double bond in the trans configuration, resulting in a more linear shape. The presence of a trans double bond in a fatty acid chain results in a smaller bond angle, or kink, than in a cis double bond, resulting in a fatty acid chain conformation that is more similar to a saturated fatty acid than to an unsaturated fatty acid. Several studies have identified an association between trans-fat intake and a risk of neurodiseases, cardiometabolic disease and pro-inflammatory effects. It focuses on a series of recent studies that have supporting the pathogenic role through human or animal experiments in vitro or in vivo. Overall, the findings of this short communication suggest that fat composition is more important than the quantity of fat consumed in terms of dietary cis and trans fatty acids.
{"title":"Trans Fatty Acids, does Exist Safety Dosage?","authors":"I. Longhi","doi":"10.4172/2165-7904.1000312","DOIUrl":"https://doi.org/10.4172/2165-7904.1000312","url":null,"abstract":"Recent data regarding Trans Fatty Acids (TFAs) have implicated this lipid as being particularly deleterious to human health. TFAs are unsaturated fatty acids that contain at least one non conjugated double bond in the trans configuration, resulting in a more linear shape. The presence of a trans double bond in a fatty acid chain results in a smaller bond angle, or kink, than in a cis double bond, resulting in a fatty acid chain conformation that is more similar to a saturated fatty acid than to an unsaturated fatty acid. Several studies have identified an association between trans-fat intake and a risk of neurodiseases, cardiometabolic disease and pro-inflammatory effects. It focuses on a series of recent studies that have supporting the pathogenic role through human or animal experiments in vitro or in vivo. Overall, the findings of this short communication suggest that fat composition is more important than the quantity of fat consumed in terms of dietary cis and trans fatty acids.","PeriodicalId":243288,"journal":{"name":"Journal of obesity and weight loss therapy","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128268083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：