首页 > 最新文献

Middle East Journal of Internal Medicine最新文献

英文 中文
From the Editor 来自编辑
Pub Date : 2018-06-01 DOI: 10.5742/meim.2018.93395
A. Husari
The first Expressway in Sri Lanka was declared open recently, connecting the financial capital with southern towns of Sri Lanka. Known as the Southern Expressway (E01), the already commissioned first stage spans close to 100 km with eight interchanges. With the speed limit stipulated at 100 km/h, which is about 25% higher than comparable expressways of other countries in the region, destination transit times are reduced by more than 50% as compared to other routes. While the gain through reduced transit times is presently confined mainly to commuters, advantage of this rapid transit facility in true sense could only be derived by directing value addition to economic activities.
斯里兰卡第一条高速公路近日宣布通车,连接金融之都和斯里兰卡南部城镇。被称为南方高速公路(E01),已经投入使用的第一阶段跨越近100公里,有8个立交桥。规定的限速为100公里/小时,比该地区其他国家的同类高速公路高约25%,与其他路线相比,目的地过境时间减少了50%以上。虽然通过减少过境时间获得的收益目前主要限于通勤者,但这种快速运输设施的真正意义上的优势只能通过直接为经济活动增加价值来获得。
{"title":"From the Editor","authors":"A. Husari","doi":"10.5742/meim.2018.93395","DOIUrl":"https://doi.org/10.5742/meim.2018.93395","url":null,"abstract":"The first Expressway in Sri Lanka was declared open recently, connecting the financial capital with southern towns of Sri Lanka. Known as the Southern Expressway (E01), the already commissioned first stage spans close to 100 km with eight interchanges. With the speed limit stipulated at 100 km/h, which is about 25% higher than comparable expressways of other countries in the region, destination transit times are reduced by more than 50% as compared to other routes. While the gain through reduced transit times is presently confined mainly to commuters, advantage of this rapid transit facility in true sense could only be derived by directing value addition to economic activities.","PeriodicalId":243742,"journal":{"name":"Middle East Journal of Internal Medicine","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132029325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Medical Treatment of Metabolic Syndrome in the Fourth Decade 第四个十年代谢综合征的医学治疗
Pub Date : 2018-06-01 DOI: 10.5742/MEIM.2018.93397
M. Helvaci, A. Abyad, Lesley Pocock
{"title":"Medical Treatment of Metabolic Syndrome in the Fourth Decade","authors":"M. Helvaci, A. Abyad, Lesley Pocock","doi":"10.5742/MEIM.2018.93397","DOIUrl":"https://doi.org/10.5742/MEIM.2018.93397","url":null,"abstract":"","PeriodicalId":243742,"journal":{"name":"Middle East Journal of Internal Medicine","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121445807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between Maternal Anaemia and Premature Birth 产妇贫血与早产的关系
Pub Date : 2017-10-01 DOI: 10.5742/MEIM.2017.93041
Rema Khlaif Omosh, N. Alfayez, I. Fayez
Objective: This study was designed to assess the relation between maternal anaemia in the third trimester and premature birth. Methods: A case-control study was conducted in Prince Hashim hospital and Prince Ali Hospital in the period between August 2015 and July 2016. A total of 200 women were included in the study and divided into two groups. Group A consisted of patients delivered between 24-37 weeks of gestation (case group), while Group B consisted of patients delivered after 37 weeks (control group). Maternal anaemia was defined as haemoglobin level < 11g/ dL and preterm delivery was defined as delivery prior to 37 weeks of gestation. Patients with haemoglobinopathies, systemic diseases, Antepartum haemorrhage and multiple gestations were excluded from the analysis. Results: In Group A, 47 patients were found to be anaemic while 53 patients had normal haemoglobin. In Group B, 29 patients were found to be anaemic while 71 patients had normal haemoglobin. Conclusion: It was observed that maternal anaemia in the third trimester, at labour, was associated with an increased risk of prematurity.
目的:本研究旨在评估妊娠晚期孕妇贫血与早产的关系。方法:2015年8月- 2016年7月在哈希姆王子医院和阿里王子医院进行病例对照研究。共有200名女性参与了这项研究,并被分为两组。A组为妊娠24-37周分娩的患者(病例组),B组为妊娠37周后分娩的患者(对照组)。孕妇贫血定义为血红蛋白水平< 11g/ dL,早产定义为妊娠37周前分娩。有血红蛋白病、全身性疾病、产前出血和多胎妊娠的患者排除在分析之外。结果:A组贫血47例,血红蛋白正常53例。B组29例贫血,71例血红蛋白正常。结论:据观察,产妇贫血在妊娠晚期,在分娩时,与早产的风险增加有关。
{"title":"Association between Maternal Anaemia and Premature Birth","authors":"Rema Khlaif Omosh, N. Alfayez, I. Fayez","doi":"10.5742/MEIM.2017.93041","DOIUrl":"https://doi.org/10.5742/MEIM.2017.93041","url":null,"abstract":"Objective: This study was designed to assess the relation between maternal anaemia in the third trimester and premature birth. Methods: A case-control study was conducted in Prince Hashim hospital and Prince Ali Hospital in the period between August 2015 and July 2016. A total of 200 women were included in the study and divided into two groups. Group A consisted of patients delivered between 24-37 weeks of gestation (case group), while Group B consisted of patients delivered after 37 weeks (control group). Maternal anaemia was defined as haemoglobin level < 11g/ dL and preterm delivery was defined as delivery prior to 37 weeks of gestation. Patients with haemoglobinopathies, systemic diseases, Antepartum haemorrhage and multiple gestations were excluded from the analysis. Results: In Group A, 47 patients were found to be anaemic while 53 patients had normal haemoglobin. In Group B, 29 patients were found to be anaemic while 71 patients had normal haemoglobin. Conclusion: It was observed that maternal anaemia in the third trimester, at labour, was associated with an increased risk of prematurity.","PeriodicalId":243742,"journal":{"name":"Middle East Journal of Internal Medicine","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115405630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Local Side Effects of Inhalers in Patients with COPD in KHMC 慢性阻塞性肺病患者吸入器的局部副反应
Pub Date : 2017-10-01 DOI: 10.5742/meim.2017.93040
R. M. Haddad, Jafar A. Al-Momani, Adnan S. Al Suleihat
{"title":"Local Side Effects of Inhalers in Patients with COPD in KHMC","authors":"R. M. Haddad, Jafar A. Al-Momani, Adnan S. Al Suleihat","doi":"10.5742/meim.2017.93040","DOIUrl":"https://doi.org/10.5742/meim.2017.93040","url":null,"abstract":"","PeriodicalId":243742,"journal":{"name":"Middle East Journal of Internal Medicine","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120961750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Paclitaxel-Carboplatin versus Bevacizumab Paclitaxel-Carboplatin for Treatment of Non-Small-Cell Lung Cancer 紫杉醇-卡铂与贝伐单抗紫杉醇-卡铂治疗非小细胞肺癌
Pub Date : 2017-10-01 DOI: 10.5742/MEIM.2017.93042
Waleed Hammam, Y. Saleh
Background: Lung cancer is considered as the leading cause attributed to cancer related deaths and approximately 85% of lung cancer patients have non-small-cell lung cancer (NSCLC) and Vascular endothelial growth factor (VEGF) is used to play the major role in regulation of angiogenesis in malignancies. Aim: The aim of this study was to compare chemotherapy alone in comparison with addition of anti -vegf (bevacizumab) to chemotherapy and assessment of response rate , progression free survival, overall survival in patients diagnosed with nonsquamous non small cell lung cancer in Saudi German hospitals in the period between March 2013 and February 2016. Patients and methods: This study was held between March 2013 and February 2016 in Saudi German hospitals when we performed a randomized study in which 40 patients with recurrent or advanced nonsmall-cell lung cancer (stage IIIB or IV) received paclitaxel and carboplatin (paclitaxel-carboplatin arm) (20 patients) paclitaxel and carboplatin in addition to bevacizumab (paclitaxel-carboplatin-bevacizumab arm) (20 patients). Results: The median overall survival was 15.5 months in the paclitaxel-carboplatin-bevacizumab arm as compared with 10.5 months in the paclitaxelcarboplatin arm ( P=0.002) and the median progression-free survival was also significantly improved in the paclitaxel-carboplatin-bevacizumab arm reaching (8.4 months versus 5.9 in the paclitaxel-carboplatin arm) for a hazard ratio for disease progression of 0.67 (95% CI, 0.57 to 0.77; P<0.001) and the addition of bevacizumab to paclitaxel and carboplatin improved the response rate as (25 %) in the paclitaxel-carboplatin arm had a response versus (65%) in the paclitaxel-carboplatin-bevacizumab arm (P<0.001) and the rates of hypertension, bleeding, thrombocytopenia, neutropenia, febrile neutropenia, proteinuria were significantly higher in the paclitaxel-carboplatin-bevacizumab arm than in the paclitaxel-carboplatin arm. (P<0.05). Conclusion: The addition of bevacizumab to the chemotherapy added a significant value to the patients with non squamous NSCLC in terms of response rate, progression free survival and overall survival however with significant side effects.
背景:肺癌被认为是癌症相关死亡的主要原因,约85%的肺癌患者为非小细胞肺癌(NSCLC),血管内皮生长因子(VEGF)在恶性肿瘤血管生成的调控中起主要作用。目的:本研究的目的是比较2013年3月至2016年2月期间在沙特-德国医院诊断为非鳞状非小细胞肺癌的患者单独化疗与联合抗vegf(贝伐单抗)化疗的反应率、无进展生存期和总生存期。患者和方法:本研究于2013年3月至2016年2月在沙特德国医院进行,我们进行了一项随机研究,其中40例复发或晚期非小细胞肺癌(IIIB或IV期)患者接受紫杉醇和卡铂(紫杉醇-卡铂组)(20例)紫杉醇和卡铂加贝伐单抗(紫杉醇-卡铂-贝伐单抗组)(20例)。结果:紫杉醇-卡铂-贝伐单抗组的中位总生存期为15.5个月,而紫杉醇-卡铂-贝伐单抗组为10.5个月(P=0.002),紫杉醇-卡铂-贝伐单抗组的中位无进展生存期也显著提高(8.4个月,紫杉醇-卡铂组为5.9个月),疾病进展的风险比为0.67 (95% CI, 0.57至0.77;P<0.001),贝伐单抗加入紫杉醇和卡铂提高了反应率,因为紫杉醇-卡铂组(25%)有反应,而紫杉醇-卡铂-贝伐单抗组(65%)有反应(P<0.001),并且紫杉醇-卡铂-贝伐单抗组的高血压、出血、血小板减少症、中性粒细胞减少症、发热性中性粒细胞减少症、蛋白尿的发生率显著高于紫杉醇-卡铂组。(P < 0.05)。结论:贝伐单抗联合化疗对非鳞状NSCLC患者在缓解率、无进展生存期和总生存期方面有显著的增加价值,但副作用明显。
{"title":"Paclitaxel-Carboplatin versus Bevacizumab Paclitaxel-Carboplatin for Treatment of Non-Small-Cell Lung Cancer","authors":"Waleed Hammam, Y. Saleh","doi":"10.5742/MEIM.2017.93042","DOIUrl":"https://doi.org/10.5742/MEIM.2017.93042","url":null,"abstract":"Background: Lung cancer is considered as the leading cause attributed to cancer related deaths and approximately 85% of lung cancer patients have non-small-cell lung cancer (NSCLC) and Vascular endothelial growth factor (VEGF) is used to play the major role in regulation of angiogenesis in malignancies. Aim: The aim of this study was to compare chemotherapy alone in comparison with addition of anti -vegf (bevacizumab) to chemotherapy and assessment of response rate , progression free survival, overall survival in patients diagnosed with nonsquamous non small cell lung cancer in Saudi German hospitals in the period between March 2013 and February 2016. Patients and methods: This study was held between March 2013 and February 2016 in Saudi German hospitals when we performed a randomized study in which 40 patients with recurrent or advanced nonsmall-cell lung cancer (stage IIIB or IV) received paclitaxel and carboplatin (paclitaxel-carboplatin arm) (20 patients) paclitaxel and carboplatin in addition to bevacizumab (paclitaxel-carboplatin-bevacizumab arm) (20 patients). Results: The median overall survival was 15.5 months in the paclitaxel-carboplatin-bevacizumab arm as compared with 10.5 months in the paclitaxelcarboplatin arm ( P=0.002) and the median progression-free survival was also significantly improved in the paclitaxel-carboplatin-bevacizumab arm reaching (8.4 months versus 5.9 in the paclitaxel-carboplatin arm) for a hazard ratio for disease progression of 0.67 (95% CI, 0.57 to 0.77; P<0.001) and the addition of bevacizumab to paclitaxel and carboplatin improved the response rate as (25 %) in the paclitaxel-carboplatin arm had a response versus (65%) in the paclitaxel-carboplatin-bevacizumab arm (P<0.001) and the rates of hypertension, bleeding, thrombocytopenia, neutropenia, febrile neutropenia, proteinuria were significantly higher in the paclitaxel-carboplatin-bevacizumab arm than in the paclitaxel-carboplatin arm. (P<0.05). Conclusion: The addition of bevacizumab to the chemotherapy added a significant value to the patients with non squamous NSCLC in terms of response rate, progression free survival and overall survival however with significant side effects.","PeriodicalId":243742,"journal":{"name":"Middle East Journal of Internal Medicine","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123774560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lower the Triglyceride, Longer the Survival 降低甘油三酯,延长生存期
Pub Date : 2017-10-01 DOI: 10.5742/MEIM.2017.93045
M. Helvaci, O. Ayyıldız, Orhan Ekrem Muftuoglu
Background: We tried to determine the safest triglyceride value in the plasma. Methods: Check up cases with a triglyceride value lower than 60 mg/dL were collected into the first, lower than 100 mg/dL into the second, lower than 150 mg/dL into the third, lower than 200 mg/dL into the fourth, and equal to or greater than 200 mg/dL into the fifth groups, respectively. Results: Study included 478 cases (288 females and 190 males), totally. Mean values of age, body weight, body mass index, triglyceride, and low density lipoprotein cholesterol and prevalences of smoking, white coat hypertension (WCH), hypertension, type 2 diabetes mellitus (DM), and coronary artery disease (CAD) increased nearly in all steps from the first towards the fifth groups, gradually and significantly (p<0.05). Conclusions: Probably metabolic syndrome is a chronic inflammatory process mainly affecting the vascular endothelium all over the body and terminating with early aging and premature death. The syndrome has reversible parameters including sedentary life style, animal-rich diet, overweight, smoking, alcohol, hypertriglyceridemia, hyperbetalipoproteinemia, dyslipidemia, impaired fasting glucose, impaired glucose tolerance, WCH, chronic inflammations and infections and irreversible end points including obesity, hypertension, DM, cirrhosis, peripheric artery disease, chronic obstructive pulmonary disease, chronic renal disease, CAD, mesenteric ischemia, osteoporosis, and stroke. Hypertriglyceridemia may be one of the most significant reversible parameters of the syndrome, and it is better to have the lowest plasma triglyceride value as much as possible to live longer.
背景:我们试图确定血浆中最安全的甘油三酯值。方法:将甘油三酯值低于60 mg/dL的病例分为第一组,低于100 mg/dL的病例分为第二组,低于150 mg/dL的病例分为第三组,低于200 mg/dL的病例分为第四组,等于或大于200 mg/dL的病例分为第五组。结果:共纳入478例,其中女性288例,男性190例。年龄、体重、体重指数、甘油三酯和低密度脂蛋白胆固醇的平均值以及吸烟、白毛高血压(WCH)、高血压、2型糖尿病(DM)和冠状动脉疾病(CAD)的患病率几乎在从第一组到第五组的所有步骤中都增加,逐渐且显著(p<0.05)。结论:代谢综合征可能是一种主要影响全身血管内皮的慢性炎症过程,最终以早衰、早死而告终。该综合征具有可逆参数,包括久坐不动的生活方式、富含动物的饮食、超重、吸烟、饮酒、高甘油三酯血症、高脂蛋白血症、血脂异常、空腹血糖受损、糖耐量受损、WCH、慢性炎症和感染,以及不可逆终点,包括肥胖、高血压、糖尿病、肝硬化、外周动脉疾病、慢性阻塞性肺病、慢性肾病、CAD、肠系膜缺血、骨质疏松症和中风。高甘油三酯血症可能是该综合征最重要的可逆参数之一,血浆甘油三酯值越低越好,寿命越长。
{"title":"Lower the Triglyceride, Longer the Survival","authors":"M. Helvaci, O. Ayyıldız, Orhan Ekrem Muftuoglu","doi":"10.5742/MEIM.2017.93045","DOIUrl":"https://doi.org/10.5742/MEIM.2017.93045","url":null,"abstract":"Background: We tried to determine the safest triglyceride value in the plasma. Methods: Check up cases with a triglyceride value lower than 60 mg/dL were collected into the first, lower than 100 mg/dL into the second, lower than 150 mg/dL into the third, lower than 200 mg/dL into the fourth, and equal to or greater than 200 mg/dL into the fifth groups, respectively. Results: Study included 478 cases (288 females and 190 males), totally. Mean values of age, body weight, body mass index, triglyceride, and low density lipoprotein cholesterol and prevalences of smoking, white coat hypertension (WCH), hypertension, type 2 diabetes mellitus (DM), and coronary artery disease (CAD) increased nearly in all steps from the first towards the fifth groups, gradually and significantly (p<0.05). Conclusions: Probably metabolic syndrome is a chronic inflammatory process mainly affecting the vascular endothelium all over the body and terminating with early aging and premature death. The syndrome has reversible parameters including sedentary life style, animal-rich diet, overweight, smoking, alcohol, hypertriglyceridemia, hyperbetalipoproteinemia, dyslipidemia, impaired fasting glucose, impaired glucose tolerance, WCH, chronic inflammations and infections and irreversible end points including obesity, hypertension, DM, cirrhosis, peripheric artery disease, chronic obstructive pulmonary disease, chronic renal disease, CAD, mesenteric ischemia, osteoporosis, and stroke. Hypertriglyceridemia may be one of the most significant reversible parameters of the syndrome, and it is better to have the lowest plasma triglyceride value as much as possible to live longer.","PeriodicalId":243742,"journal":{"name":"Middle East Journal of Internal Medicine","volume":"120 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121085710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Hypertriglyceridemia May Actually Be an Acute Phase Reactant in the Plasma 高甘油三酯血症实际上可能是血浆中的急性相反应物
Pub Date : 2017-10-01 DOI: 10.5742/MEIM.2017.93043
M. Helvaci, M. Davarci, O. Ozkan
Results: One hundred and forty-four cases either with cholelithiasis or cholecystectomy for cholelithiasis were detected among 3,437 cases, totally (4.1%). One hundred and sixteen (80.1%) of them were females with a mean age of 53.6 years. Obesity (54.8% versus 43.7%, p<0.01), body mass index (BMI) (31.0 versus 28.9 kg/m2, p<0.01), and hypertension (26.3% versus 13.1%, p<0.001) were significantly higher in the cholelithiasis or cholecystectomy group. Although the prevalence of hyperbetalipoproteinemia was significantly lower in the cholelithiasis or cholecystectomy group (9.7% versus 18.0%, p<0.05), hypertriglyceridemia (25.0% versus 18.0%, p<0.05) was significantly higher in them.
结果:3437例患者中,合并胆结石或胆囊切除术合并胆结石者144例(4.1%)。其中女性116例(80.1%),平均年龄53.6岁。肥胖(54.8%比43.7%,p<0.01)、体重指数(BMI)(31.0比28.9 kg/m2, p<0.01)和高血压(26.3%比13.1%,p<0.001)在胆结石或胆囊切除术组中显著升高。尽管胆石症组和胆囊切除术组的高脂蛋白血症发生率显著低于对照组(9.7%比18.0%,p<0.05),但高甘油三酯血症发生率显著高于对照组(25.0%比18.0%,p<0.05)。
{"title":"Hypertriglyceridemia May Actually Be an Acute Phase Reactant in the Plasma","authors":"M. Helvaci, M. Davarci, O. Ozkan","doi":"10.5742/MEIM.2017.93043","DOIUrl":"https://doi.org/10.5742/MEIM.2017.93043","url":null,"abstract":"Results: One hundred and forty-four cases either with cholelithiasis or cholecystectomy for cholelithiasis were detected among 3,437 cases, totally (4.1%). One hundred and sixteen (80.1%) of them were females with a mean age of 53.6 years. Obesity (54.8% versus 43.7%, p<0.01), body mass index (BMI) (31.0 versus 28.9 kg/m2, p<0.01), and hypertension (26.3% versus 13.1%, p<0.001) were significantly higher in the cholelithiasis or cholecystectomy group. Although the prevalence of hyperbetalipoproteinemia was significantly lower in the cholelithiasis or cholecystectomy group (9.7% versus 18.0%, p<0.05), hypertriglyceridemia (25.0% versus 18.0%, p<0.05) was significantly higher in them.","PeriodicalId":243742,"journal":{"name":"Middle East Journal of Internal Medicine","volume":"143 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133988564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Histopathological Findings in Hysterectomy Specimens : A Retrospective Study 子宫切除术标本的组织病理学发现:回顾性研究
Pub Date : 2017-10-01 DOI: 10.5742/MEIM.2017.93046
O. Mohamed, Mazen Abood Ben Thabet
This is a retrospective study of descriptive patterns of findings seen in hysterectomy specimens based on records from a Modern histopathology laboratory in Aden. A total of 2,544 specimens were analyzed during the 6 years period from January 2006 to December 2012, to study the histopathological findings of these specimens. The age of the patients at hysterectomy ranged from 16-80 years with a mean of 44.6, with the maximum patients (56.3 %) in the age group 41-50 years and less patients in less than 30 years. Most common pathology findings are; Endometrial hyperplasia 1481 (58.3%), Non neoplastic cystic lesion 1386 (54.5%), Chronic cervicitis 1363 (53.6%), Adenomyosis 793 (31.2% ) follow by Leiomyoma 697 (27.4%). Other less frequent pathologies identified included atrophic endometrium, Inadequate secretory endometrial transformation, Gestational Trophoblastic disease, Endometroid adenocarcinoma, cervical prolapse. This study confirms that benign pathologies are more common in hysterectomy specimens than their malignant counterparts.
这是基于亚丁现代组织病理学实验室记录的子宫切除术标本中发现的描述性模式的回顾性研究。对2006年1月至2012年12月6年间共2544例标本进行分析,研究标本的组织病理学结果。子宫切除术患者年龄16 ~ 80岁,平均44.6岁,41 ~ 50岁患者最多(56.3%),30岁以下患者较少。最常见的病理表现是;子宫内膜增生1481例(58.3%)、非肿瘤性囊性病变1386例(54.5%)、慢性宫颈炎1363例(53.6%)、子宫腺肌病793例(31.2%)、平滑肌瘤697例(27.4%)。其他不常见的病理包括子宫内膜萎缩、分泌不足的子宫内膜转化、妊娠滋养细胞疾病、子宫内膜样腺癌、宫颈脱垂。本研究证实良性病变在子宫切除术标本中比恶性病变更常见。
{"title":"Histopathological Findings in Hysterectomy Specimens : A Retrospective Study","authors":"O. Mohamed, Mazen Abood Ben Thabet","doi":"10.5742/MEIM.2017.93046","DOIUrl":"https://doi.org/10.5742/MEIM.2017.93046","url":null,"abstract":"This is a retrospective study of descriptive patterns of findings seen in hysterectomy specimens based on records from a Modern histopathology laboratory in Aden. A total of 2,544 specimens were analyzed during the 6 years period from January 2006 to December 2012, to study the histopathological findings of these specimens. The age of the patients at hysterectomy ranged from 16-80 years with a mean of 44.6, with the maximum patients (56.3 %) in the age group 41-50 years and less patients in less than 30 years. Most common pathology findings are; Endometrial hyperplasia 1481 (58.3%), Non neoplastic cystic lesion 1386 (54.5%), Chronic cervicitis 1363 (53.6%), Adenomyosis 793 (31.2% ) follow by Leiomyoma 697 (27.4%). Other less frequent pathologies identified included atrophic endometrium, Inadequate secretory endometrial transformation, Gestational Trophoblastic disease, Endometroid adenocarcinoma, cervical prolapse. This study confirms that benign pathologies are more common in hysterectomy specimens than their malignant counterparts.","PeriodicalId":243742,"journal":{"name":"Middle East Journal of Internal Medicine","volume":"1 11","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120857518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Moderate Iron Deficiency Anemia in the Treatment of Metabolic Syndrome 中度缺铁性贫血在代谢综合征治疗中的作用
Pub Date : 2017-10-01 DOI: 10.5742/meim.2017.93044
M. Helvaci, M. Albayrak, O. Balçik
Background: Body mass index (BMI), weight, and height may be due to various hereditary and environmental factors. Material and methods: Age and sex-matched cases with a hematocrit value of less than 30% were collected into the first, less than 36% into the second, less than 40% into the third, and 40% or greater into the fourth groups of patients. Results: The study included 108 anemia patients (101 females) with a mean age of 34.7 years (range 15-68). The anemia cases were mainly iron deficiency anemia and/or thalassemia minors. When we compared the first group with the second, the BMI and weight were significantly retarded in the first group (23.6 versus 26.9 kg/m2, p= 0.005 and 61.3 versus 69.9 kg, p= 0.008), whereas there were nonsignificant differences between the second, third, and fourth groups for both (p>0.05 for all). Although there was significantly retarded BMI and weight in the first group, body heights were similar in the four groups (p>0.05 for all). Conclusion: Although the BMI and weight can be affected by moderate anemia, the height may strongly be determined by heredity. Since the excess weight may be a significant underlying cause of the metabolic syndrome, and the metabolic syndrome shortens human lifespan significantly, and there is no case with shortened survival due to iron deficiency anemia and/or thalassemia minors, an iatrogenic and moderate iron deficiency anemia with frequent blood donation may prolong human survival by decreasing the BMI and weight in the overweight and obese individuals.
背景:身体质量指数(BMI)、体重和身高可能受各种遗传和环境因素的影响。材料与方法:将年龄与性别匹配且红细胞压积值小于30%的患者分为第一组,小于36%的患者分为第二组,小于40%的患者分为第三组,大于40%的患者分为第四组。结果:本研究纳入贫血患者108例(女性101例),平均年龄34.7岁(15-68岁)。贫血病例以缺铁性贫血和/或未成年地中海贫血为主。当我们将第一组与第二组进行比较时,第一组的BMI和体重显著延迟(23.6对26.9 kg/m2, p= 0.005, 61.3对69.9 kg, p= 0.008),而第二、第三和第四组之间的差异无统计学意义(p>0.05)。虽然第1组患者BMI和体重均有明显的发育迟缓,但4组患者身高无明显差异(p>0.05)。结论:中度贫血对BMI和体重有影响,但对身高有强烈的遗传决定作用。由于超重可能是代谢综合征的重要潜在原因,而代谢综合征会显著缩短人的寿命,且没有因缺铁性贫血和/或未成年地中海贫血而缩短生存期的病例,因此医源性和中度缺铁性贫血伴频繁献血可通过降低超重和肥胖个体的BMI和体重来延长人类生存期。
{"title":"Moderate Iron Deficiency Anemia in the Treatment of Metabolic Syndrome","authors":"M. Helvaci, M. Albayrak, O. Balçik","doi":"10.5742/meim.2017.93044","DOIUrl":"https://doi.org/10.5742/meim.2017.93044","url":null,"abstract":"Background: Body mass index (BMI), weight, and height may be due to various hereditary and environmental factors. Material and methods: Age and sex-matched cases with a hematocrit value of less than 30% were collected into the first, less than 36% into the second, less than 40% into the third, and 40% or greater into the fourth groups of patients. Results: The study included 108 anemia patients (101 females) with a mean age of 34.7 years (range 15-68). The anemia cases were mainly iron deficiency anemia and/or thalassemia minors. When we compared the first group with the second, the BMI and weight were significantly retarded in the first group (23.6 versus 26.9 kg/m2, p= 0.005 and 61.3 versus 69.9 kg, p= 0.008), whereas there were nonsignificant differences between the second, third, and fourth groups for both (p>0.05 for all). Although there was significantly retarded BMI and weight in the first group, body heights were similar in the four groups (p>0.05 for all). Conclusion: Although the BMI and weight can be affected by moderate anemia, the height may strongly be determined by heredity. Since the excess weight may be a significant underlying cause of the metabolic syndrome, and the metabolic syndrome shortens human lifespan significantly, and there is no case with shortened survival due to iron deficiency anemia and/or thalassemia minors, an iatrogenic and moderate iron deficiency anemia with frequent blood donation may prolong human survival by decreasing the BMI and weight in the overweight and obese individuals.","PeriodicalId":243742,"journal":{"name":"Middle East Journal of Internal Medicine","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116567680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Assisted Vaginal Deliveries in Far South of Jordan 在约旦南部协助阴道分娩
Pub Date : 2017-04-01 DOI: 10.5742/MEIM.2017.92939
Mitri Rashed, Areej Bisharat, B. Nusair
Objective: To determine the rate, indications and complications of instrumental deliveries at Prince Hashim Ben Abdullah The Second Hospital (former name Princess Haya Bent Al-Hussein), Aqaba, Jordan. Methods: This retrospective observational study has been carried out over a four-year period between 1st January 2012 and 31st December 2015. The medical records of all patients who underwent instrumental deliveries were reviewed and analyzed. Results: During this four-year period 238 successful instrumental deliveries were performed out of 9,767 deliveries with a rate of 2.56%. The commonest instrument used was vacuum (202/240) and 36 patients were delivered by forceps. The indications were; presumed fetal distress (132), prolonged 2nd stage of labor (85) and maternal exhaustion (21). Maternal complications reported were postpartum hemorrhage (18) and different degrees of genital tract tears (28). Fetal complications registered consisted of 34 cases of which (11) were cases of Erbs palsy, (12) were cases admitted to NICU for observation and one case was diagnosed with cerebral palsy. Conclusion: Our study showed a lower rate of operative vaginal delivery in comparison to the international figures. This may be attributed to the lack of epidural anesthesia which increases the incidence of instrumental deliveries, in addition to the simple experience of the attending residents who fear possible complications of applying these instruments and the potential subsequent litigation. The complications reported in our study were expected in assisted vaginal deliveries (AVD) and mimic those mentioned in the literature.
目的:了解约旦亚喀巴哈希姆·本·阿卜杜拉王子第二医院(原名哈亚·本特·侯赛因公主)器械分娩的发生率、适应证和并发症。方法:这项回顾性观察性研究在2012年1月1日至2015年12月31日的四年期间进行。对所有器械分娩患者的医疗记录进行了回顾和分析。结果:4年期间9767例分娩中器械分娩238例成功,成功率2.56%。最常用的器械是真空(202/240),36例患者使用产钳分娩。迹象是;推定胎儿窘迫(132),延长第二产程(85)和产妇疲惫(21)。产妇并发症包括产后出血(18例)和不同程度的生殖道撕裂(28例)。本组共记录34例胎儿并发症,其中11例为Erbs性麻痹,12例为NICU观察,1例诊断为脑瘫。结论:与国际数据相比,我们的研究显示阴道手术分娩率较低。这可能是由于硬膜外麻醉的缺乏增加了器械分娩的发生率,以及住院医师的简单经验,他们担心使用这些器械可能出现并发症和潜在的后续诉讼。本研究报告的并发症是在辅助阴道分娩(AVD)中预期的,并模仿文献中提到的并发症。
{"title":"Assisted Vaginal Deliveries in Far South of Jordan","authors":"Mitri Rashed, Areej Bisharat, B. Nusair","doi":"10.5742/MEIM.2017.92939","DOIUrl":"https://doi.org/10.5742/MEIM.2017.92939","url":null,"abstract":"Objective: To determine the rate, indications and complications of instrumental deliveries at Prince Hashim Ben Abdullah The Second Hospital (former name Princess Haya Bent Al-Hussein), Aqaba, Jordan. Methods: This retrospective observational study has been carried out over a four-year period between 1st January 2012 and 31st December 2015. The medical records of all patients who underwent instrumental deliveries were reviewed and analyzed. Results: During this four-year period 238 successful instrumental deliveries were performed out of 9,767 deliveries with a rate of 2.56%. The commonest instrument used was vacuum (202/240) and 36 patients were delivered by forceps. The indications were; presumed fetal distress (132), prolonged 2nd stage of labor (85) and maternal exhaustion (21). Maternal complications reported were postpartum hemorrhage (18) and different degrees of genital tract tears (28). Fetal complications registered consisted of 34 cases of which (11) were cases of Erbs palsy, (12) were cases admitted to NICU for observation and one case was diagnosed with cerebral palsy. Conclusion: Our study showed a lower rate of operative vaginal delivery in comparison to the international figures. This may be attributed to the lack of epidural anesthesia which increases the incidence of instrumental deliveries, in addition to the simple experience of the attending residents who fear possible complications of applying these instruments and the potential subsequent litigation. The complications reported in our study were expected in assisted vaginal deliveries (AVD) and mimic those mentioned in the literature.","PeriodicalId":243742,"journal":{"name":"Middle East Journal of Internal Medicine","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126641013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Middle East Journal of Internal Medicine
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1