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Participation Rates In Epidemiology Studies And Surveys: A Review 2007–2015 流行病学研究和调查的参与率:2007-2015年综述
Pub Date : 2016-01-26 DOI: 10.5580/IJE.34897
C. Keeble, P. Baxter, Stuart Barber, G. Law
Understanding the factors associated with participation is key in addressing the problem of declining participation rates in epidemiological studies. This review aims to summarise factors affecting participation rates in articles published during the last nine years, to compare with previous findings to determine whether the research focus for non-participation has changed and whether the findings have been consistent over time. Web of Science was used to search titles of English articles from 2007–2015 for a range of synonymous words concerning participation rates. A predefined inclusion criteria was used to determine whether the resulting articles referred to participation in the context of study enrolment. Factors associated with participation were extracted from included articles. The search returned 626 articles, of which 162 satisfied the inclusion criteria. Compared with pre-2007, participant characteristics generally remained unchanged, but were topic-dependent. An increased focus on study design and a greater use of technology for enrolment and data collection was found, suggesting a transition towards technology-based methods. In addition to increased participation rates, studies should consider any bias arising from non-participation. When reporting results, authors are encouraged to include a standardised participation rate, a calculation of potential bias, and to apply an appropriate statistical method where appropriate. Requirements from journals to include these would allow for easier comparison of results between studies.
了解与参与有关的因素是解决流行病学研究参与率下降问题的关键。本综述旨在总结过去九年中发表的文章中影响参与率的因素,并与以前的研究结果进行比较,以确定不参与的研究重点是否发生了变化,以及研究结果是否随着时间的推移而保持一致。Web of Science被用来搜索2007-2015年的英文文章标题,寻找一系列与参与率相关的同义词。使用预定义的纳入标准来确定所得到的文章是否涉及研究入组的参与。从纳入的文章中提取与参与相关的因素。检索结果为626篇,其中162篇符合纳入标准。与2007年前相比,参与者的特征基本保持不变,但具有话题依赖性。研究发现,人们越来越关注研究设计,并更多地使用技术进行登记和数据收集,这表明人们正在向基于技术的方法过渡。除了增加参与率外,研究还应考虑不参与所产生的偏见。在报告结果时,鼓励作者包括标准化的参与率,潜在偏差的计算,并在适当的地方应用适当的统计方法。期刊的要求包括这些内容,可以更容易地比较研究之间的结果。
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引用次数: 23
Population Migration Through Railroads And Spatial Diffusion Of Polio In India: A Cross-Sectional Pr 通过铁路的人口迁移和小儿麻痹症在印度的空间扩散:一项横断面研究
Pub Date : 2013-05-15 DOI: 10.5580/IJE.1633
Ananda S. Bandyopadhyay, J. Blossom, J. Wenger, M. Castro
Background The recent occurrence of polio outbreaks in countries previously considered polio-free such as Tajikistan, Russia and China, and the economic and public health burden of managing such outbreaks underscored the importance of importation of infectious diseases across geographical regions, transcending political boundaries. It also questioned the appropriateness of classifying geographic regions, countries, states and provinces, as endemic and non-endemic and the implications such classifications had on the quality of surveillance and immunization strategies. Although molecular epidemiology and field-surveys have been useful in demonstrating the possible source of reintroduction of virus transmission in disease-free areas, the mode of importation often remains unexplored. The goal of this study is to explore the role played by popular modes of transport, such as the railways, in the importation of polio transmission from endemic to non-endemic states in India. Methods To explore the association between cases in non-endemic states and the geographical distribution of the railroads, we evaluate the spatial pattern of spread of polio from endemic to non-endemic states in India during the last four years (as of April 2013) of virus circulation in the country, 2008 2011, in a cross-sectional design. We geo-coded addresses of serotype 1 (P-1) cases followed by mapping and proximity analysis using geo-spatial tools. Fisher’s exact 2-tailed test was used to assess the statistical significance of the proximity analysis. Results Our analysis established that cases in non-endemic states were more likely (64.7% in non-endemic states compared to 38.9% in endemic states) to be geographically closer to the railroads compared to cases in endemic states. The results were statistically significant (Fisher’s exact 2-tailed P: 0.01) and the null hypothesis of no association between location of P-1 cases in non-endemic areas and proximity to the railroads was rejected. All P-1 wild type cases (n = 173) from all states and Union Territories in India were included for the most recent 4-year period, and knowing the predominant sub-clinical nature of polio infection, the results were based on a robust set of data from a large cohort of infected population.
塔吉克斯坦、俄罗斯和中国等以前被认为无脊髓灰质炎的国家最近发生脊髓灰质炎疫情,以及管理这种疫情的经济和公共卫生负担,突出了跨越地理区域、超越政治边界的传染病输入的重要性。它还质疑将地理区域、国家、州和省划分为流行和非流行是否适当,以及这种分类对监测和免疫战略的质量所产生的影响。虽然分子流行病学和实地调查有助于证明病毒在无病地区再次传播的可能来源,但输入模式往往尚未探索。本研究的目的是探讨流行的运输方式,如铁路,在输入脊髓灰质炎传播中所起的作用,从印度的流行州到非流行州。方法为了探讨非流行邦病例与铁路地理分布之间的关系,我们采用横断面设计评估了2008年至2011年印度病毒传播的最后四年(截至2013年4月)中脊髓灰质炎从流行邦到非流行邦的传播空间格局。我们对血清型1 (P-1)病例的地址进行地理编码,然后使用地理空间工具进行制图和邻近分析。使用Fisher精确双尾检验来评估接近性分析的统计显著性。结果我们的分析表明,与流行州的病例相比,非流行州的病例更有可能(非流行州为64.7%,而流行州为38.9%)在地理上更靠近铁路。结果具有统计学意义(Fisher 's精确双尾P: 0.01), P-1病例在非流行地区的位置与靠近铁路之间没有关联的原假设被拒绝。所有来自印度各邦和联邦领土的P-1野生型病例(n = 173)被纳入最近4年期间的研究,并且了解脊髓灰质炎感染的主要亚临床性质,结果基于来自大量受感染人群的一组可靠数据。
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引用次数: 2
An Approach to Comparing Nations for Inclusion of Studies in Health-based Systematic Literature Reviews 一种比较国家纳入基于健康的系统文献综述研究的方法
Pub Date : 2012-01-24 DOI: 10.5580/2ba0
R. Deonandan, H. Schachter, Mylan Ly, D. Lacroix, Ceri Moore, N. Barrowman, Idil Abdulkadir, A. Girardi
Background: To develop and demonstrate a systematic approach for comparing nations, for the purpose of deciding whether to include or exclude studies in a systematic review of a health research question pertinent to the Canadian population. Results: a template of nine criteria was developed, including both sociodemographic and systemic indicators, and was applied to 68 jurisdictions, of which 19 were deemed sufficiently comparable to Canada to be included in the review. Conclusions: Subsequent systematic reviews, regardless of which nation is ultimately the reference population, should employ a similar process, with indicators and characteristics specific to the research questions, to ensure that political, economic, historical or ethnic biases are not influencing the selection or rejection of relevant papers.
背景:为了决定是否在与加拿大人口相关的健康研究问题的系统评价中纳入或排除研究,开发并演示了一种比较国家的系统方法。结果:制定了包括社会人口统计和系统指标在内的9个标准模板,并应用于68个司法管辖区,其中19个被认为与加拿大具有足够的可比性,可以纳入审查。结论:后续的系统评价,无论哪个国家是最终的参考人群,都应该采用类似的过程,具有特定于研究问题的指标和特征,以确保政治、经济、历史或种族偏见不会影响相关论文的选择或拒绝。
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引用次数: 0
Adjusting Structural Equation Modelling Of Spiritual Coping Scale: Use Of The Sattora-Bentler Method As An Alternative To Maximum Likelihood Estimation 调整精神应对量表的结构方程模型:使用Sattora-Bentler方法替代最大似然估计
Pub Date : 2012-01-24 DOI: 10.5580/2ba1
Mohmad Taghi Khodayari, Alireza Abadi, H. A. Majd, M. Rassouli, H. Sadeghi-Bazargani
Background: Structural equation modelling (SEM) is a multivariate analysis method used to investigate direct and indirect effects among several observed or latent variables. In psychology and social sciences, data are often collected through questionnaires or inventories that commonly include Likert scale questions. Multivariate normal distribution is an essential assumption that often does not hold for this kind of data. Through an experiment on spiritual coping, our study aimed to illustrate key problems associated with using the common maximum likelihood (ML) method, and to assess a way for dealing with structural equation models when variables are in categorical form and don’t exhibit a normal and continuous distribution. Methods:Data regarding measurement of spiritual coping and its predictors collected through a questionnaire were analysed. A structural model was developed and specified for spiritual coping. The model was fitted and investigated to assess common fit indices and Sattora-bentler estimators for small samples and non-normal Likert scale data. Data analysis and modelling was done using the EQS statistical software package. Results:It was found that fit indices and parameters encountered underestimation problems when using common ML estimator method. The robust SB-χ method showed the model to have a better fit to the data ((S-B 2 )/ df) = 1.82, CFI = 0.94)). Conclusion:Structural equation modelling using a robust SB-estimator is an appropriate method for analysing complex Likert scale measurements, especially with a small sample size, specifically regarding the spiritual coping scale and similar metrics. INTRODUCTION Nearly everyone working in research fields of psychology and neuropsychiatric diseases is acquainted with the Likerttype scale. The Likert scale was invented by a psychologist called Likert Rensis . Although general applicability of Likert scales has been often questioned, this type of measurement remains an extremely popular methodology in the fields of psychology, public health and nursing research. In fact, it is so widely used in scaling responses in surveys that it is sometimes used interchangeably with rating scales, even though the two are not synonymous. Analysis of data measured on Likert scales is another issue requiring special notation. A variable measured using Likert type questions exists on an ordinal scalegenerally one limited to a few levels. This poses the question of whether we can safely apply statistical methods that rely on assumptions of normality. The issue gets even more problematic when the sample size is small and a complex model needs to be developed to assess a latent variable representative of a health-related phenomenon. Structural equation modelling (SEM) is a statistical methodology that takes a confirmatory (i.e. hypothesistesting) approach to the analysis of a structural theory bearing on some phenomenon. Typically, this theory represents “causal” processes that generate observation
背景:结构方程模型(SEM)是一种多变量分析方法,用于研究几个观察变量或潜在变量之间的直接和间接影响。在心理学和社会科学中,数据通常通过问卷或清单收集,通常包括李克特量表问题。多元正态分布是一个重要的假设,但通常不适用于这类数据。通过一项关于精神应对的实验,我们的研究旨在说明与使用公共最大似然(ML)方法相关的关键问题,并评估当变量为分类形式且不呈现正态和连续分布时处理结构方程模型的方法。方法:通过问卷调查收集心理应对的测量数据及预测因素进行分析。一种结构模型被发展和指定为精神应对。对模型进行拟合和研究,以评估小样本和非正态李克特尺度数据的常见拟合指数和Sattora-bentler估计。采用EQS统计软件包进行数据分析和建模。结果:使用普通ML估计方法时,拟合指标和参数存在低估问题。稳健的SB-χ方法显示模型与数据有更好的拟合((S-B 2)/ df) = 1.82, CFI = 0.94)。结论:结构方程建模使用稳健的sb估计器是分析复杂李克特量表测量的合适方法,特别是在小样本量的情况下,特别是关于精神应对量表和类似指标。几乎每个在心理学和神经精神疾病研究领域工作的人都熟悉李克特量表。李克特量表是由心理学家李克特·伦西斯发明的。尽管李克特量表的普遍适用性经常受到质疑,但这种测量方法在心理学、公共卫生和护理研究领域仍然是一种非常流行的方法。事实上,它是如此广泛地应用于调查中的反应尺度,有时它与评级量表互换使用,即使这两者不是同义词。在李克特量表上测量的数据分析是另一个需要特殊符号的问题。使用李克特类型问题测量的变量存在于一个有序的尺度上,通常局限于几个层次。这就提出了一个问题,即我们能否安全地应用依赖于正态性假设的统计方法。当样本量很小,需要开发一个复杂的模型来评估与健康有关的现象的潜在变量时,这个问题就变得更加棘手了。结构方程建模(SEM)是一种统计方法,它采用验证(即假设)的方法来分析与某些现象有关的结构理论。通常,这一理论代表了在多个变量上产生观察结果的“因果”过程。回顾过去15年的扫描电镜应用(至少在心理学研究中),发现大多数测量都是基于李克特缩放数据,使用最大似然(ML)程序对参数进行估计。当类别数量较大且数据近似于正态分布时,未能解决精神应对量表的调整结构方程建模:使用Sattora-Bentler方法替代数据的7序数形式的最大似然估计2可能具有可忽略不计的后果;然而,在许多研究中可能并非如此。在心理学和其他社会科学中,数据通常是通过使用李克特量表的问卷收集的。多元正态性是一个基本假设,但可能不适用于这类数据。在一项评估精神应对的实验中,我们的研究目的是说明使用公共最大似然(ML)方法的问题,并评估当变量为分类形式且不遵循正态分布和连续分布时处理结构方程模型的方法。材料和方法数据来自德黑兰国家福利组织数据库中的120名青少年。数据来自德黑兰19个保护中心登记的14-20岁的孤儿青少年。一种结构模型被发展和指定为精神应对。编制的量表被称为“制度化青少年精神应对量表”。使用ML的常见拟合指标和Sattora-bentler估计器对小样本和非正态Likert尺度数据进行拟合和研究结构统计模型。SATTORA-BENTLER METHOD () ML方法产生参数估计器,以确保观察到的样本概率最大化。该方法假定观测变量具有多正态分布。似然函数为:
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引用次数: 1
Socioeconomic And Maternal Determinants Of Infant Mortality: An Analysis Using The Swaziland Demographic Health Survey 2007 婴儿死亡率的社会经济和母亲决定因素:2007年斯威士兰人口健康调查分析
Pub Date : 2012-01-24 DOI: 10.5580/2b4a
E. Zwane
This paper uses the 2007 Swaziland Demographic and Health Survey to investigate the impact of socioeconomic and maternal variables on infant survival. Results indicate that children born using Caesarean section had a higher risk of infant mortality. The infant mortality risk associated with multiple births was about 4 times higher relative to singleton births. Socioeconomic variables did not have a distinct impact on infant mortality. These results suggest that improving maternal and child health services, screening for high-risk pregnancies and making referral services for high-risk pregnancies more accessible, particularly to the rural women and children, will also contribute to improvement of infant survival rates.
本文利用2007年斯威士兰人口与健康调查来调查社会经济和产妇变量对婴儿存活率的影响。结果表明,使用剖腹产出生的儿童有较高的婴儿死亡率。多胎婴儿的死亡率是单胎婴儿的4倍。社会经济变量对婴儿死亡率没有明显的影响。这些结果表明,改善孕产妇和儿童保健服务、筛查高危妊娠和使高危妊娠转诊服务更容易获得,特别是对农村妇女和儿童,也将有助于提高婴儿存活率。
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引用次数: 4
Educational Seminars For Atopic Patients, A New French Series. 特应症患者教育研讨会,一个新的法国系列。
Pub Date : 2012-01-24 DOI: 10.5580/2b1b
S. Osdoit, G. Guillet
Objective: to determine the immediate impact of educational seminars on the selfmanagement of patients with moderate to severe atopic dermatitis.Design: Prospective single centre studyPatients: 346 patients, 128 children (age 0 to 10 years), 18 teenagers (age 11 to 17 years) and 197 adults (age 18 to more than 61 years), taking part in educational seminars in La Roche Posay thermal health resort between 2008 and 2009.Results: Before the seminar, 27% patients never received information about atopia. 18% patients never use steroids because of fear. 78% patients declared a regular use of moisturizing therapy. 92% patients found an interest in the seminar. 80% patients thought that the advice and recommendations provided during the session would improve their self-management of eczema.Conclusion: This new series assess the behavioural changing after the educative session and the strong need of personalized information in atopic patients.Écouter Lire phonétiquement
目的:探讨教育研讨会对中重度特应性皮炎患者自我管理的直接影响。设计:前瞻性单中心研究。患者:346名患者,128名儿童(0至10岁),18名青少年(11至17岁)和197名成年人(18至61岁以上),在2008年至2009年期间参加了La Roche Posay热疗度假村的教育研讨会。结果:研讨会前,27%的患者从未接受过有关斜视的信息。18%的患者因为害怕而从不使用类固醇。78%的患者声称定期使用保湿疗法。92%的患者对研讨会感兴趣。80%的患者认为会议期间提供的意见和建议将改善他们对湿疹的自我管理。结论:本研究评估了特应性过敏患者在接受教育后的行为改变和对个性化信息的强烈需求。Écouter生活电话通讯
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引用次数: 0
Maternal Health Correlates Of Neonatal Deaths In A Tribal Area In India 印度部落地区孕产妇健康与新生儿死亡的相关性
Pub Date : 2012-01-24 DOI: 10.5580/2cc4
G. Babu, S. Ramachandra, Ushashree Garikipati, T. Mahapatra, S. Mahapatra, S. Narayana, Hira Pant
ObjectivesIn tribal areas of India, the coverage of antenatal care service is poor and rate of home delivery is very high Moreover, most of these deliveries are either unattended or attended by unskilled traditional birth attendants. Evidences suggest that the rate of neonatal mortality is also very high in these areas. The aim of the current study was to explore maternal factors, explicitly focusing on antenatal care and maternal health seeking pattern in relation to neonatal health in tribal areas of Andhra Pradesh, India. Study designThis community based study was conducted in two phases: the first phase involved use of qualitative methods and aided in obtaining relevant information in the quantitative phase from mothers who had delivered in the one year period prior to the study. MethodsInformation from analysis of qualitative data was used to construct a questionnaire, which was administered in the subsequent quantitative phase wherein a population-based survey was undertaken. Reported infant deaths were investigated through verbal autopsy. Multi-stage systematic random sampling was used to identify study participants. The study recruited 230 subjects for the quantitative study. All women of the reproductive age group (15 � 45 years) in the tribal areas of Vizianagaram district of Andhra Pradesh state were eligible for the study. ResultsAmong the 230 women studied, 74% utilized public health facilities for antenatal care (ANC) and the provision of ANC services was good with high coverage of Tetanus toxoid (97%) and excellent provision of IFA tablets (93%). Our results also show that 56% of women delivered at home, 38% at a public health facility and 5.2% could avail private facility. Qualified doctors conducted only 10% of deliveries and 29% were conducted by ANM. Age of mother, total number of women in the
在印度的部落地区,产前保健服务的覆盖率很低,在家分娩的比率很高。此外,这些分娩中的大多数要么无人照料,要么由不熟练的传统接生员照料。有证据表明,这些地区的新生儿死亡率也非常高。本研究的目的是探讨与印度安得拉邦部落地区新生儿健康有关的孕产妇因素,明确关注产前保健和孕产妇保健寻求模式。这项基于社区的研究分两个阶段进行:第一阶段使用定性方法,并在定量阶段从研究前一年内分娩的母亲那里获得相关信息。方法利用定性数据分析所得的信息编制问卷,并在随后的定量阶段进行人口调查。报告的婴儿死亡是通过尸检进行调查的。采用多阶段系统随机抽样方法确定研究对象。该研究招募了230名受试者进行定量研究。安得拉邦Vizianagaram地区部落地区的所有育龄妇女(15 - 45岁)都有资格参加这项研究。结果在研究的230名妇女中,74%利用公共卫生设施进行产前保健(ANC), ANC服务提供良好,破伤风类毒素覆盖率高(97%),IFA片剂提供良好(93%)。我们的结果还表明,56%的妇女在家中分娩,38%在公共卫生机构分娩,5.2%可以利用私人设施分娩。合格的医生只完成了10%的分娩,29%的分娩是由ANM完成的。年龄的母亲,总人数的妇女
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引用次数: 7
Prevalence Of Hypertension And Diabetes Mellitus Among People Seeking Cataract Surgery In Rural South India 印度南部农村寻求白内障手术的人群中高血压和糖尿病的患病率
Pub Date : 2012-01-24 DOI: 10.5580/2af6
B. Behera, K. Satish, S. Jena, M. Hussain, Soumya Samal
Objective: To know the prevalence of hypertension and diabetes mellitus among people seeking cataract surgery in the rural population. Study Design: Cross sectional study. Setting: Study was carried out at G.S.L. Medical College & General Hospital, Rajahmundry, Andhra Pradesh, India. Participants: Cases of cataract requiring surgery. Methodology: People were screened for cataract at village level eye camps and an ophthalmology outpatient department. The study group consisted of diagnosed cases of senile cataract, who were admitted to the hospital for surgery. All the cases were screened for hypertension and diabetes mellitus before surgery. Statistical Analysis: Percentages, Z-test, & chi-square test. Results: Out of 1627 cases, 49% were male and 51% were female. The prevalence of hypertension & diabetes mellitus was 20.59% & 5.9% respectively. Among 795 male cases, 13.8% have hypertension, whereas the prevalence of diabetes mellitus was 4.7%. The prevalence of hypertension & diabetes mellitus among 832 female cases was 24.5% and 4.4% respectively. Conclusions: Chronic diseases like hypertension and diabetes are usually present among cataract cases. Early detection and proper control will greatly delay the development and progress of complications This paper was presented in the 35 th annual National IAPSM conference, 23 rd -25 th January 2008, held at JIPMER
目的:了解农村白内障手术患者中高血压和糖尿病的患病率。研究设计:横断面研究。环境:研究在印度安得拉邦拉贾蒙德里的G.S.L.医学院和总医院进行。参与者:需要手术的白内障病例。方法:在村级眼科营和眼科门诊对患者进行白内障筛查。研究组由诊断为老年性白内障的患者组成,这些患者入院接受手术治疗。所有病例术前均行高血压和糖尿病筛查。统计分析:百分比、z检验、卡方检验。结果:1627例患者中,男性占49%,女性占51%。高血压和糖尿病患病率分别为20.59%和5.9%。795例男性患者中高血压占13.8%,糖尿病占4.7%。832例女性患者中高血压和糖尿病患病率分别为24.5%和4.4%。结论:白内障患者常伴有高血压、糖尿病等慢性疾病。早期发现和适当控制将大大延缓并发症的发展和进展。本文发表于2008年1月23日至25日在JIPMER举行的第35届全国IAPSM年会上
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引用次数: 7
Perspectives, Constructs And Methods In The Measurement Of Multimorbidity And Comorbidity: A Critical Review 多重病和共病测量的观点、结构和方法:综述
Pub Date : 2012-01-24 DOI: 10.5580/2CC3
T. Haregu, B. Oldenburg, G. Setswe, J. Elliott
Background: There is no question about the importance of measuring multimorbidity and comorbidity. However, reviews of measures of multimorbidity/comorbidity are limited to multimorbidity indices that are used to predict mortality, disability, healthrelated quality of life and healthcare costs at individual level. Objective: To describe the perspectives, constructs and methods used in the measurement of multimorbidity and comorbidity. Methods: A structured literature search for studies reporting the measurement of multimorbidity or comorbidity was conducted in Medline and Embase. The references of the identified papers were consulted without restriction. The methods used by other researches that have reported on multimorbidity and comorbidity were also reviewed. The findings of the review are summarized under major constructs of multimorbidity and comorbidity. Results: Multimorbidity/comorbidity measurements involve the consideration of several perspectives. The four major constructs of multimorbidity/comorbidity measurement are magnitude, severity, pattern and burden. There are two major approaches of measuring multimorbidity and comorbidity. The first approach reduces measurements of multiple diseases to a single condition and the second approach uses clustering of diseases and cases in to relevant non-random groups. Conclusion: The measurement of multimorbidity involves multiple perspectives, constructs and methods.
背景:测量多病和共病的重要性是毋庸置疑的。然而,对多重疾病/共病措施的审查仅限于用于预测死亡率、残疾、与健康相关的生活质量和个人医疗保健费用的多重疾病指数。目的:介绍多病和共病测量的视角、结构和方法。方法:在Medline和Embase中对报道多重疾病或共病测量的研究进行结构化文献检索。不受限制地查阅了所确定论文的参考文献。并对多病和共病的研究方法进行了综述。本文根据多病和共病的主要概念对研究结果进行了总结。结果:多病/共病的测量涉及到几个方面的考虑。多重疾病/共病测量的四个主要结构是量级、严重程度、模式和负担。有两种主要的方法来测量多重病和共病。第一种方法将多种疾病的测量减少到单一条件,第二种方法将疾病和病例聚类到相关的非随机组中。结论:多重发病率的测量涉及多个视角、结构和方法。
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引用次数: 6
Do you see an elephant or just its trunk?The need of learning Modern Epidemiologic Methods: An introduction 你看到大象了吗,还是只是它的鼻子?学习现代流行病学方法的必要性:介绍
Pub Date : 2012-01-24 DOI: 10.5580/2a67
G. Babu
There is famous story wherein several blind men were asked what is the elephant is like. While one of them said it is like a pillar, another man said “snake” and each talked of it differently as they felt it. 1 In epidemiology, many of the hypotheses being evaluated in the interpretation of studies can be seen as auxiliary hypothesis in the sense that each blind person is feeling the elephant and describing individual experience. Particularly, each observation is independent of the presence, absence or direction of any causal connection between the study exposure and the disease. Much of the interpretation of epidemiological studies amounts to the testing of such auxiliary explanations for observed associations. 2
有一个著名的故事,几个盲人被问到大象是什么样子的。其中一个说它像一根柱子,另一个说它像“蛇”,每个人都根据自己的感受来谈论它。在流行病学中,许多在解释研究中被评估的假设可以被视为辅助假设,因为每个盲人都在感受大象并描述个人经历。特别是,每次观察都独立于研究暴露与疾病之间存在、不存在或方向上的任何因果关系。流行病学研究的许多解释相当于对观察到的关联的这种辅助解释的检验。2
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引用次数: 1
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The Internet Journal of Epidemiology
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