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Assessment of Heart Failure Patients in a Tertiary Care Hospital: A Retrospective Study 三级医院心力衰竭患者评估:一项回顾性研究
Pub Date : 2023-07-08 DOI: 10.3329/bhj.v38i1.67220
Md. Toufiqur Rahman, RA Ahmed, Rumi Alam, M. A. Hossain, Md Sarowar Hossain, M. A. Hossain, Mohammad Nasimul Goni, Md Sajjadur Rahman, Mohammad Faridul Hoque, Manobendra Sarker
Background: Heart failure is a complex syndrome that arises from abnormalities in the structure and/or function of the heart, whether inherited or acquired. It impairs the ability of the left ventricle to fill or eject blood, leading to a growing number of hospitalizations, deaths, and healthcare costs worldwide. According to the Global Burden of Disease Study 2019, heart failure affected approximately 64 million people worldwide in 2019, and caused over 3 million deaths. The prevalence of heart failure has been increasing worldwide, with an estimated 26% increase in age-standardized prevalence and a 14% increase in age-standardized incidence between 1990 and 2019. This increase in prevalence and incidence is due to a variety of factors, including the aging of the population, improved survival rates from other cardiovascular diseases, and changes in lifestyle and risk factors such as obesity and diabetes. Heart failure patients have various presentations and different etiologies. This study aimed to describe the baseline characteristics, associated co-morbid conditions, presenting features, and causes of heart failure in a study population of 3650 patients admitted to Colonel Maleque Medical College, Manikganj. Methods: This study was done to see Clinical Presentation of Heart Failure Patients admitted in Colonel Maleque Medical College, Manikganj and Maikganj Sadar Hospital. A total of 3650 patients were enrolled in this study during the period of April 2018 to March 2023. Results: Most of the patients (60%) were of 51-70 years age group. 70 % (2555) patients were male. 99% patients presented with SOB, 95% patients had basal creps, 70% had orthopnoea, 49% had Paroxysmal Nocturnal Dyspoea (PND), 40% had leg edema and 25% had raised JVP. Average heart rate was 84 beats/min, average systolic B.P. was 128 mm Hg and average diastolic B.P. was 76 mm Hg. 49% population had hypertension, 39% patients had diabetes and 28% had concomitant respiratory illness. Average EF was 37 %. Ischemic Cardiomyopathy was the commonest (40%) cause of heart failure, acute coronary syndrome was the second leading (30%) cause, valvular heart disease and hypertension are the third common causes. Conclusion: This study highlights the significant burden of heart failure in a population of patients admitted to a tertiary care hospital in Bangladesh. The findings underscore the importance of early detection and management of risk factors for heart failure, such as hypertension and diabetes, to prevent the development and progression of this condition. The identification of the most common causes of heart failure may guide targeted prevention and management strategies in this population. Most common causes are ischemic cardiomyopathy, a sequel of ischemic insult of the heart. So, patients of acute or chronic ischemic heart diseases should be treated and followed up with care, considering their socioeconomic conditions also. Bangladesh Heart Journal 2023; 38(1): 63-69
背景:心力衰竭是由心脏结构和/或功能异常引起的复杂综合征,无论是遗传性的还是获得性的。它损害了左心室充血或喷射血液的能力,导致世界范围内越来越多的住院、死亡和医疗费用。根据《2019年全球疾病负担研究》,2019年全球约有6400万人患有心力衰竭,造成300多万人死亡。在世界范围内,心力衰竭的患病率一直在上升,据估计,1990年至2019年间,年龄标准化患病率增加了26%,年龄标准化发病率增加了14%。患病率和发病率的增加是由于多种因素造成的,包括人口老龄化、其他心血管疾病的存活率提高、生活方式的改变以及肥胖和糖尿病等风险因素。心力衰竭患者有不同的表现和不同的病因。本研究旨在描述Manikganj马勒克上校医学院(Colonel Maleque Medical College)收治的3650例患者的基线特征、相关合并症、表现特征和心力衰竭原因。方法:对马勒克上校医学院、Manikganj和Maikganj Sadar医院住院的心力衰竭患者的临床表现进行研究。在2018年4月至2023年3月期间,共有3650名患者入组该研究。结果:51 ~ 70岁年龄组患者居多(60%)。男性2555例,占70%。99%的患者表现为SOB, 95%的患者有基础皱纹,70%的患者有直鼻痛,49%的患者有阵发性夜间呼吸困难(PND), 40%的患者有腿部水肿,25%的患者有JVP升高。平均心率84次/分,平均收缩压128毫米汞柱,平均舒张压76毫米汞柱。49%的患者患有高血压,39%的患者患有糖尿病,28%的患者伴有呼吸系统疾病。平均EF为37%。缺血性心肌病是心力衰竭最常见的原因(40%),急性冠状动脉综合征是第二大原因(30%),瓣膜性心脏病和高血压是第三常见的原因。结论:本研究强调了在孟加拉国三级医院住院的患者中心力衰竭的显著负担。研究结果强调了早期发现和管理心力衰竭风险因素的重要性,如高血压和糖尿病,以防止这种情况的发生和发展。确定心力衰竭的最常见原因可以指导有针对性的预防和管理策略。最常见的原因是缺血性心肌病,这是心脏缺血性损伤的后遗症。因此,对于急慢性缺血性心脏病患者,在考虑其社会经济状况的同时,也应给予谨慎的治疗和随访。孟加拉国心脏杂志2023;38 (1): 63 - 69
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引用次数: 0
Echocardiographic Evaluation of Atrial Septal Defects and Clinical Applications; A Focused Review 房间隔缺损的超声心动图评价及临床应用重点回顾
Pub Date : 2022-12-28 DOI: 10.3329/bhj.v37i2.63137
N. Fatema
Atrial septal defect (ASD) is a commonly encountered congenital lesion in paediatric and adult populations and accounts for 8-10 % of all congenital heart disease. Echocardiography is the most sensitive and specific imaging tool to diagnose this condition and also to determine management guidelines. Various modalities of echocardiography imaging can assess atrial septal defects completely with associated changes in cardiac chambers, haemodynamic status, relationship with neighboring structures, suitability for percutaneous closure or need for surgical intervention. Echocardiography can guide percutaneous device closure procedure as well.Bangladesh Heart Journal 2022; 37(2): 130-138
房间隔缺损(ASD)是儿科和成人人群中常见的先天性病变,占所有先天性心脏病的8- 10%。超声心动图是诊断这种疾病和确定治疗指南的最敏感和最特异的成像工具。各种超声心动图成像方式可以完全评估房间隔缺损,包括心室的相关变化、血流动力学状态、与邻近结构的关系、是否适合经皮缝合或是否需要手术干预。超声心动图也可以指导经皮装置闭合手术。孟加拉国心脏杂志2022;37 (2): 130 - 138
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引用次数: 0
ABO Blood Group and Severity of Coronary Artery Disease Assessed by Syntax Score in Patients with Acute Myocardial 句法评分评价急性心肌患者ABO血型与冠状动脉疾病严重程度
Pub Date : 2022-12-28 DOI: 10.3329/bhj.v37i2.63134
Md Zillur Rahman, S. Chowdhury, I. J. Shimu, P. Biswas, A. Towab, A. K. Das, Khurshadul Alam, A. Mahmud, Khondoker Al Monsur Helal
Introduction: As coronary artery disease (CAD) is a major cause of morbidity and mortality; timely diagnosis and appropriate therapy is of paramount importance to improve clinical outcomes. Though there are major risk factors for CAD but sometimes it does not correlate with ACS. So, search for new risk factor is necessary for better management of CAD specially STEMI. Aim: To see the association between ABO blood group and severity of CAD in patients with STEMI.Methods: This study was done during the period of January 2016 to June 2016 with STEMI at National Institute of Cardiovascular diseases, Dhaka, Bangladesh. 100 patients were grouped in I and II where group-I having 50 patients of non-O blood group and group-II having 50 patients of O blood group. After CAG all reports were analyzed by two experts and SYNTAX score were calculated and data were analyzed by SPSS.Results: Baseline characteristics (100 patients) were well matched between the groups. Low SYNTAX score (d”22) was 16% and 56%; intermediate score (23-32) was 40% and 36% and high score (>32) was 44% and 8% in group- I and group-II respectively. These indicate that patients of non-O blood group have high SYNTAX score that is more severe CAD. Univariate and multivariate regression analysis showed that non-O blood group is an independent risk factor for CAD. So easily available ABO blood grouping can be helpful to determine the severity of CAD in patients with STEMI.Bangladesh Heart Journal 2022; 37(2): 107-115
导论:由于冠状动脉疾病(CAD)是发病率和死亡率的主要原因;及时的诊断和适当的治疗对改善临床结果至关重要。虽然冠心病有主要的危险因素,但有时它与ACS无关。因此,寻找新的危险因素对于更好地管理冠心病特别是STEMI是必要的。目的:探讨STEMI患者ABO血型与冠心病严重程度的关系。方法:本研究于2016年1月至2016年6月在孟加拉国达卡国立心血管疾病研究所进行STEMI,将100例患者分为I和II组,其中I组有50例非O型血患者,II组有50例O型血患者。CAG结束后,所有报告由两位专家进行分析,计算SYNTAX评分,并用SPSS软件对数据进行分析。结果:基线特征(100例)组间匹配良好。低SYNTAX评分(d " 22)分别为16%和56%;中度评分(23 ~ 32分)占40%、36%,高评分(>32分)占44%、8%。提示非o型血患者SYNTAX评分高,冠心病加重。单因素和多因素回归分析显示,非o型血是冠心病的独立危险因素。因此,易于获得的ABO血型可以帮助确定STEMI患者CAD的严重程度。孟加拉国心脏杂志2022;37 (2): 107 - 115
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引用次数: 0
Association of Serum Vitamin D level with in-hospital Outcome in Patients with Acute Myocardial infarction 急性心肌梗死患者血清维生素D水平与住院预后的关系
Pub Date : 2022-12-28 DOI: 10.3329/bhj.v37i2.63132
Khandaker Abu Rubaiyat, A. Chowdhury, Mohsin Ahmed, Md Gaffar Amin, Atm Mahfuzul Hoque, K. Islam, Chowdhury Md Kudrat E Khuda, Abm Imam Hosen, M. Haque
Objective: Vitamin D deficiency is emerging as a new risk factor for various cardiovascular events. Several studies have been done to find out association of vitamin D level with CAD with varying Results. Very few studies, however, have investigated the association between serum vitamin D levels and clinical outcomes in ACS patients thus far. The  Objective of this study was to assess the association between serum vitamin D levels and in-hospital complications of AMI patients in Department of Cardiology, Dhaka Medical College Hospital (DMCH), Dhaka.Methods: This was a cross-sectional observational study. We measured serum vitamin D level in AMI (STEMI and NSTEMI) patients (n=198) admitted in Department of Cardiology, DMCH. Patients with normal vitamin D level (e”30 ng/ml) were considered as Group I and patients with low serum vitamin D level (<30 ng/ml) were considered as Group II; and in-hospital complications were evaluated.Results: The study showed that 51% of study subjects of AMI had in-hospital complications; 71.1% patients with low vitamin D level had adverse in-hospital outcome whereas 14.3% patients with normal vitamin D level had AMI complications which was statistically significant (p<0.001). Heart failure and arrhythmias were the most frequently observed complications. The Results of the study demonstrates that the association between low vitamin D level and in-hospital complications after AMI remains statistically significant (p<0.001).Conclusions: Low serum vitamin D level is independently associated with a higher frequency of several in-hospital adverse clinical events including mortality after acute myocardial infarction (STEMI and NSTEMI). Whether low vitamin D levels represent a risk marker or a risk factor in ACS remains to be elucidated.Bangladesh Heart Journal 2022; 37(2): 89-98
目的:维生素D缺乏正在成为各种心血管事件的一个新的危险因素。已经进行了几项研究,以找出维生素D水平与CAD之间的关系,结果各不相同。然而,迄今为止,很少有研究调查了ACS患者血清维生素D水平与临床结果之间的关系。本研究的目的是评估达卡医学院医院(DMCH)心内科AMI患者血清维生素D水平与住院并发症的关系。方法:这是一项横断面观察研究。我们测定了198例在DMCH心内科住院的AMI (STEMI和NSTEMI)患者的血清维生素D水平。维生素D水平正常(e " 30 ng/ml)的患者为I组,血清维生素D水平低(<30 ng/ml)的患者为II组;并对院内并发症进行评估。结果:研究显示51%的AMI患者有院内并发症;71.1%维生素D水平低的患者发生AMI并发症,14.3%维生素D水平正常的患者发生AMI并发症,差异有统计学意义(p<0.001)。心衰和心律失常是最常见的并发症。研究结果表明,低维生素D水平与AMI后住院并发症之间的相关性仍然具有统计学意义(p<0.001)。结论:低血清维生素D水平与包括急性心肌梗死(STEMI和NSTEMI)后死亡在内的几种院内不良临床事件的较高频率独立相关。低维生素D水平是否代表ACS的危险标志或危险因素仍有待阐明。孟加拉国心脏杂志2022;37 (2): 89 - 98
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引用次数: 0
Blood Pressure Screening at a Non-Government Tertiary Care Hospital in Bangladesh: A Pilot Study 孟加拉国一家非政府三级医院的血压筛查:一项试点研究
Pub Date : 2022-12-28 DOI: 10.3329/bhj.v37i2.63131
M. Khanom, Md Akhtarul Islam Chowdhury, Md. Amir Hossain
Objective: The general  Objective of this pilot study was to unveil the findings of blood pressure screening program at a Non-Government Tertiary Care Hospital in Bangladesh. The specific  Objectives were to find out socio-demographic profile of the participants, to categorize the blood pressure readings according to the defined variables, to select among the participants who would require intervention and to encourage people in order to adopt healthy diet as well as lifestyle behaviors.Methods: It was a cross-sectional study conducted at outpatient department of Chattagarm International Medical College Hospital (CIMCH), Shamsherpara, Chattogram from 16.05.2022 to 19.05.2022. The study participants were volunteers of 18 years or older who wished to get the free blood pressure checkup on observation of world hypertension day at CIMCH outpatient premises.Results: Altogether 232 patients participated in the blood pressure screening program, 10.7% were pre-hypertensives and 11.2% had high blood pressure; none of them visited any physician previously for checking blood pressure. Pre-existing hypertensives constituted 16.4% of total participants; nearly half of them had good compliance to medication or life style modification. The maximum (26 out of 51) ‘pre-hypertensive’ and ‘high blood pressure’ were in the 30-49 years age group.Conclusion: Community based blood pressure screening and patient education covering a wider area can be an effective approach to reduce the burden of hypertension as well its conquences on the patient, family, society, nation, and the globe. The Results of the current pilot study might provide preliminary data and encourage for future prospective studies.Bangladesh Heart Journal 2022; 37(2): 84-88
目的:本初步研究的总体目的是揭示孟加拉国一家非政府三级保健医院的血压筛查计划的结果。具体目标是找出参与者的社会人口统计资料,根据定义的变量对血压读数进行分类,选择需要干预的参与者,并鼓励人们采取健康的饮食和生活方式行为。方法:横断面研究于2022年5月16日至2022年5月19日在Shamsherpara Chattagarm国际医学院医院(CIMCH)门诊部进行。研究参与者是18岁或以上的志愿者,他们希望在世界高血压日当天在CIMCH门诊进行免费血压检查。结果:共有232例患者参与血压筛查项目,10.7%为高血压前期,11.2%为高血压;他们之前都没有去看过医生检查血压。既往高血压患者占总参与者的16.4%;近一半的人对药物治疗或改变生活方式有良好的依从性。“高血压前期”和“高血压”最多(51人中有26人)发生在30-49岁年龄组。结论:以社区为基础的血压筛查和更广泛的患者教育是减轻高血压负担的有效途径,也是减轻高血压对患者、家庭、社会、国家和全球的影响的有效途径。目前的初步研究结果可能为未来的前瞻性研究提供初步数据和鼓励。孟加拉国心脏杂志2022;37 (2): 84 - 88
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引用次数: 0
3D Mapping and Ablation of Left Sided Atypical Atrial Flutter 左侧不典型心房扑动的三维定位和消融
Pub Date : 2022-12-28 DOI: 10.3329/bhj.v37i2.63138
P. Bala, A. Saxena, A. Jaswal, Amitesh Chakravarty, Ravikanth Telikicherla, Nighat Islam, M. Khan
Atypical atrial flutter has become amenable to catheter ablation with remarkable improvement in the acute and long-term efficacy of this therapy for this macro reentrant atrial arrhythmia. Here it was described a case of atypical atrial flutter which arises from left atrium and demonstrates the importance of a systematic approach to mapping and ablating atypical atrial flutter to prevent a recurrence of symptomatic arrhythmia. We also highlighted importance of 3D mapping which is a key tool for analysis and successful ablation.Bangladesh Heart Journal 2022; 37(2): 139-142
非典型心房扑动已成为适合导管消融在急性和长期疗效显著改善这种宏观心房心律失常治疗。在这里,它被描述了一个不典型心房扑动的情况下,从左心房产生,并证明了一个系统的方法来定位和消融不典型心房扑动的重要性,以防止复发的症状性心律失常。我们还强调了3D测绘的重要性,它是分析和成功消融的关键工具。孟加拉国心脏杂志2022;37 (2): 139 - 142
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引用次数: 0
Lutembacher’s Syndrome in a young female treated Surgically: A Case Report 手术治疗年轻女性Lutembacher综合征一例报告
Pub Date : 2022-12-28 DOI: 10.3329/bhj.v37i2.63139
Sultan Sarwar Parvez, S. Gupta, Reazul Haque, J. Uddin
Lutembacher’s syndrome is a rare clinical condition presenting with a combination of congenital atrial septal defect (ASD) and acquired mitral stenosis (MS). Lutembacher’s syndrome is more prevalent in developing countries and its prevalence depends on the prevalence of rheumatic fever in that geographical area. The syndrome can present at any age but is usually more commonly observed in young female adults. Echocardiography remains the gold standard for diagnosis and evaluation of Lutembacher’s syndrome (LS). Now a days many treatment options are available for LS – either percutaneous intervention or surgical correction. But pericardial patch closure of atrial septal defect and prosthetic mitral valve replacement is the treatment of choice for Lutembacher’s syndrome.Bangladesh Heart Journal 2022; 37(2): 143-147
Lutembacher综合征是一种罕见的临床病症,表现为先天性房间隔缺损(ASD)和获得性二尖瓣狭窄(MS)的结合。Lutembacher综合征在发展中国家更为普遍,其流行程度取决于该地理区域风湿热的流行程度。这种综合征可以出现在任何年龄,但通常更常见于年轻的成年女性。超声心动图仍然是诊断和评估Lutembacher综合征(LS)的金标准。现在有许多治疗方法可供选择,要么经皮介入治疗,要么手术矫正。但心包补片封闭房间隔缺损和人工二尖瓣置换术是治疗Lutembacher综合征的首选方法。孟加拉国心脏杂志2022;37 (2): 143 - 147
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引用次数: 0
In-Hospital Outcome of Patients with ST - T Changes in Non ST Segment Elevation Myocardial Infarction 非ST段抬高型心肌梗死患者ST - T改变的住院转归
Pub Date : 2022-12-28 DOI: 10.3329/bhj.v37i2.63133
Md. Shahadat Hossain, A. Jamil, A. Sarker, S. Haque, M. Ahsan, MD Ali, I. Alam
Background: This cross sectional observational study was carried out with an aim to find out in-hospital outcome in patients with ST-T changes in non-STsegment elevation myocardial infarction (NSTEMI).Methods: This cross sectional observational study was carried out in the department of cardiology, National Institute of Cardiovascular Diseases, Dhaka, Bangladesh from January 2014 to December 2014. A total of 120 patients with NSTEMI were the study population. Patients were divided into two groups on the basis of ST-T changes, 60 patients with ST-T changes were in group I and 60 patients without ST-T changes were in group II.Result: In this study, the mean age was 54.2 ±14.2 years. Male female ratio was 2.75:1 among the study population. There was no statistically significant difference in mean BMI among the two groups. Smoking was the most common risk factor present (47.5%). Smoking was found significantly more in Group I than patients of group II (p=0.02). Serum troponin I was found significantly raised in group I (42.8±5.5 vs 10.5±8.3, p=0.002). The mean left ventricular ejection fraction (LVEF) of patients in group I was significantly lower than group II (52.1±9.1% vs 61.7±6.9%. p=0.001). Adverse in-hospital outcome was significantly more in group I than group II (48.3% vs 26.7%, p=0.01). Recurrent angina pectoris, STEMI, significant arrhythmia, acute LVF and cardiogenic shock were also more in group I than in group II. In-hospital mortality was noted in group I patients with both ST segment depression and T wave inversion (6.7%). Emergency revascularization was done more commonly in patients of group I (6.7%). The mean duration of hospital stay was statistically significant between the groups (6.24±2.58 vs 4.44±1.71 days. p<0.05)). Multivariate logistic regression analysis revealed that ST-T changes are an independent predictor for developing adverse inhospital outcome in patients with non-ST-segment elevation myocardial infarction.Conclusion: The ST-segment depression and T-wave inversion on admission ECG are important predictors of outcome in patients with NSTEMI. The ST-segment depression on admission ECG of patients with NSTEMI is associated with higher adverse in hospital outcome and mortality.Bangladesh Heart Journal 2022; 37(2): 99-106
背景:本横断面观察研究旨在了解ST-T改变的非st段抬高型心肌梗死(NSTEMI)患者的住院预后。方法:本横断面观察研究于2014年1月- 2014年12月在孟加拉国达卡国立心血管疾病研究所心内科进行。共有120名NSTEMI患者作为研究人群。根据ST-T改变情况将患者分为两组,有ST-T改变的患者60例为I组,无ST-T改变的患者60例为II组。结果:本组患者平均年龄54.2±14.2岁。研究人群的男女比例为2.75:1。两组患者的平均BMI差异无统计学意义。吸烟是最常见的危险因素(47.5%)。I组吸烟明显多于II组(p=0.02)。I组血清肌钙蛋白I显著升高(42.8±5.5 vs 10.5±8.3,p=0.002)。I组患者平均左室射血分数(LVEF)明显低于II组(52.1±9.1% vs 61.7±6.9%)。p = 0.001)。不良住院结局I组明显多于II组(48.3% vs 26.7%, p=0.01)。复发性心绞痛、STEMI、明显心律失常、急性LVF和心源性休克发生率均高于II组。第一组ST段下陷和T波倒置患者的住院死亡率为6.7%。急诊血运重建术在I组患者中更为常见(6.7%)。两组患者平均住院时间(6.24±2.58天和4.44±1.71天)差异有统计学意义。p < 0.05)。多因素logistic回归分析显示ST-T变化是非st段抬高型心肌梗死患者发生不良住院预后的独立预测因子。结论:入院心电图st段下降和t波反转是预测非stemi患者预后的重要指标。非stemi患者入院心电图st段压低与较高的不良住院预后和死亡率相关。孟加拉国心脏杂志2022;37 (2): 99 - 106
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引用次数: 0
Association of Waist and Hip Ratio with the Angiographic Severity of Coronary Artery Disease in Patients with Non ST Segment Elevation Myocardial Infarction 腰臀比与非ST段抬高型心肌梗死患者冠状动脉病变血管造影严重程度的关系
Pub Date : 2022-12-28 DOI: 10.3329/bhj.v37i2.63136
M. Haque, M. Rashid, Md. Zulfikar Ali, Iftekhar Alam, Md Sukur Ahmed, A. Mamun, T. C. Shil, Golam Rahman Mallick, M. Khan, T. Ghosh, Zahidul Islam Khan, Shahriar Azad, D. Halder, P. Biswas, A. Nobi
Background: Obesity is a proven independent risk factor for coronary artery disease. There are different Methods for evaluation of obesity. The aim of this study is to evaluate the association between waist hip ratio and the severity of CAD in non-ST-segment elevation myocardial infarction patients.Methods: This cross-sectional observational study was done at the National Institute of Cardiovascular Diseases (NICVD), Dhaka. A total of 100 patients with NSTEMI who underwent coronary angiogram during the indexed hospitalization period were included in this study. On the basis of WHR, study patients were divided into two groups 50 patients of NSTEMI with normal WHR (Male <0.90, Female <0.80) were assigned as group I and 50 patients of NSTEMI with increased WHR (Male ³0.90, Female ³0.80) were assigned as group II.Results: The mean age of patients was 49.6±7.9 years and 52.3±8.7 years in Group I and Group II respectively with a male predominance in both the groups. No significant difference was found in between two groups in terms of demographic characteristics and traditional risk factors for CAD. Different parameters of angiographic severity of CAD were significantly higher in patients with increased WHR. Patients with non critical CAD (14% vs 0%, P = 0.02) and single vessel disease (58% vs 24%, P = 0.005) were more frequent in Group I, on the contrary double vessel disease (24% vs. 56%, P = 0.001) and triple vessel disease (4% vs. 20%, P = 0.03) were significantly more frequent in patients of Group II. Patients with moderate to severe CAD (Gensini score ³36) were found more in Group II than that of in Group I (24% vs. 76%, P <0.001) and there was statistically significant higher Gensini score was found in Group II (21.96±19.72 vs. 44.18±28.91, P <0.001). Significant positive correlation was found in between WHR and coronary artery disease severity measured by vessel score (r = 0.41, P < 0.001) and Gensini score (r = 0.31, P< 0.001). Multivariate regression analysis yielded that the risk of having significant CAD are 3.45 times more in patients with increased WHR than those of normal WHR (95% CI: 1.229-12.979, P = 0.01).Conclusion: Abdominal obesity, as evidenced by increased WHR, may be considered as a predictor of the severity of CAD in patients with acute NSTEMI.Bangladesh Heart Journal 2022; 37(2): 122-129
背景:肥胖是冠状动脉疾病的独立危险因素。评估肥胖有不同的方法。本研究旨在探讨非st段抬高型心肌梗死患者腰臀比与冠心病严重程度的关系。方法:本横断面观察性研究在达卡国立心血管疾病研究所(NICVD)进行。本研究共纳入100例在索引住院期间行冠状动脉造影的非stemi患者。根据WHR将研究患者分为两组,50例WHR正常(男<0.90,女<0.80)的NSTEMI患者为I组,50例WHR增高(男³0.90,女³0.80)的NSTEMI患者为II组。结果:ⅰ组和ⅱ组患者平均年龄分别为49.6±7.9岁和52.3±8.7岁,均以男性为主。在人口统计学特征和冠心病的传统危险因素方面,两组之间没有显著差异。冠心病血管造影严重程度的不同参数在WHR升高的患者中均显著升高。非危重性CAD(14%比0%,P = 0.02)和单支血管病变(58%比24%,P = 0.005)在I组中更为常见,而双支血管病变(24%比56%,P = 0.001)和三支血管病变(4%比20%,P = 0.03)在II组中更为常见。II组中重度CAD患者(Gensini评分³36)多于I组(24%比76%,P <0.001),且II组Gensini评分高于I组(21.96±19.72比44.18±28.91,P <0.001)。血管评分与冠状动脉疾病严重程度(r = 0.41, P< 0.001)、Gensini评分(r = 0.31, P< 0.001)呈正相关。多因素回归分析显示,腰重比增高患者发生显著性冠心病的风险是腰重比正常患者的3.45倍(95% CI: 1.229 ~ 12.979, P = 0.01)。结论:腹部肥胖,如腰宽比增加所证明的,可能被认为是急性NSTEMI患者CAD严重程度的预测因子。孟加拉国心脏杂志2022;37 (2): 122 - 129
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引用次数: 0
Correlation of Sum of ST Segment Depression in Leads V1 to V4 in Acute Inferior Myocardial Infarction with Angiographic Severity of Coronary Artery Disease 急性下壁心肌梗死V1 ~ V4导联ST段下降总和与冠状动脉病变严重程度的相关性
Pub Date : 2022-12-28 DOI: 10.3329/bhj.v37i2.63135
M. Badiuzzaman, Afk Ahmed, Mohammad Refatul Islam, Md Durul Hoda, Abdur Rashid, F. Ahmed, Iftekhar Alam
Background: Inferior wall acute myocardial infarction accounts for 40 to 50% of all acute STEMI. Patients of acute inferior myocardial infarction with ST depression in lateral leads often have greater incidence of triple vessel disease and proximal RCA lesion but in case of patients of acute inferior myocardial infarction with ST depression in precordial leads (leads V1 to V4), is a subject of determination whether it is associated with more sever coronary artery disease. The aim of this study is to determine the association of sum of ST depression in precordial leads with the probability of concomitant severity of coronary artery disease in patients with acute inferior STEMI.Methods: this cross sectional observational study was done at National institute of cardiovascular diseases (NICVD), Dhaka, Bangladesh. Total 90 patients of acute inferior myocardial infarction with precordial lead ST depression admitted at CCU within 12 hours of onset of chest pain were the study population. They were divided in two groups on the basis of sum of ST depression in precordial leads (Sum of ST depression d”4mm and >4mm), 36 patients in group I and 54 patients in group II. Coronary angiography was performed during the index hospitalization period. Gensini score and Reardon score were measured.Results: Overwhelming majority of the patients was male (83.3% and 90.7%) with mean age of 51.0±9.7 and 51.0±9.9 years in group I and II respectively. Smoking, hypertension and diabetes mellitus were the most frequent risk factors in both groups. Serum troponin level was significantly high in group II (6.2±2.2 vs. 13.6±17.7, p <0.05). Sum of ST depression in precordial leads was 2.84±0.66 and 7.53±3.51 in group I and group II respectively, and was statistically significant. Consideration of mean of ST depression in individual leads shows significantly higher mean in leads V2, V3 and V4 among group II patients. SVD was more frequent in group I but group II patients had higher statistically significant incidence of DVD and TVD. Gensini score (20.26±13.0 vs. 36.98±16.9) and Reardon score (4.63±2.2 vs. 6.83±2.2) was high in group II patients. Positive correlation had been depicted between summation value of ST segment depression with that of Gensini score & Reardon score (Gensini score r=0.61 and Reardon score r= 0.52).Conclusion: Involvement Triple vessel and double vessel disease was remarkably higher with increasing sum of ST segment depression in precordial leads. The severity of ST segment depression in terms of summation of ST depression in leads V1 to V4 is directly proportional to the extent and severity of coronary artery disease.Bangladesh Heart Journal 2022; 37(2): 116-121
背景:急性下壁心肌梗死占所有急性STEMI的40 - 50%。急性下壁心肌梗死伴外侧导联ST段压低的患者,其三支血管病变及近端RCA病变的发生率往往更高,但急性下壁心肌梗死伴心前导联ST段压低(V1至V4导联)的患者是否与更严重的冠状动脉病变相关,尚有待确定。本研究的目的是确定急性下段STEMI患者心前导联ST段下降与冠状动脉疾病严重程度的相关性。方法:本横断面观察性研究在孟加拉国达卡国立心血管疾病研究所(NICVD)完成。共有90例急性下壁心肌梗死伴心前导联ST段抑制的患者在胸痛发作后12小时内入住CCU。根据心前导联ST段压降之和(ST段压降之和d”4mm和>4mm)分为两组,I组36例,II组54例。在指数住院期间行冠状动脉造影。测量Gensini评分和Reardon评分。结果:ⅰ组和ⅱ组患者以男性占绝大多数(83.3%和90.7%),平均年龄分别为51.0±9.7和51.0±9.9岁。吸烟、高血压和糖尿病是两组中最常见的危险因素。II组血清肌钙蛋白水平显著高于对照组(6.2±2.2∶13.6±17.7,p <0.05)。ⅰ组和ⅱ组心前导联ST段压降总分分别为2.84±0.66和7.53±3.51,差异有统计学意义。考虑单个导联ST段压降的平均值,II组患者V2、V3和V4导联的平均值明显较高。SVD在I组发生率更高,而DVD和TVD在II组发生率更高,具有统计学意义。Gensini评分(20.26±13.0比36.98±16.9)和Reardon评分(4.63±2.2比6.83±2.2)较高。ST段凹陷的总和与Gensini评分和Reardon评分呈正相关(Gensini评分r=0.61, Reardon评分r= 0.52)。结论:随着心前导联ST段压低量的增加,累及三支及双支病变的发生率明显增高。从V1至V4导联ST段压降的总和来看,ST段压降的严重程度与冠状动脉病变的程度和严重程度成正比。孟加拉国心脏杂志2022;37 (2): 116 - 121
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引用次数: 0
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Bangladesh Heart Journal
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