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Management of Vascular Injury in a Vascular Center of a Developing Country 发展中国家某血管中心血管损伤的处理
Pub Date : 2021-09-20 DOI: 10.3329/bhj.v36i1.55515
Q. A. Azad, A. I. Khan, A. Mamun, N. Dey, Sajia Sajmin Siddiqua, Mohammad Awlad Hossain
In surgical practice management of vascular injuries are challenging. Vascular injuries are well addressed in developed countries but there is scarcity of vascular surgeons in developing countries like us and a large number of victims fail to reach specialist in time with consequent loss of limbs or lives. To observe the pattern and outcome of management of vascular injury in a developing country this retrospective study was conducted at the department of vascular surgery, National Institute of Cardiovascular Diseases (NICVD), Dhaka, Bangladesh. All patients with vascular injury arrived alive were included in the study. Date in terms of age, sex, cause of injury, segment of vessel involved, associated injuries, time elapsed after injury, vascular procedures done and postoperative complications were taken from records of the department and were analyzed. Out of 2174 patients with vascular injury 11 patients died at resuscitation & 52 did not come back after referral to other hospitals for management of associated injuries. Most of the patients were young male & road traffic accidents was the most common cause (91.50%). Majority (53.60%) of the patients presented after 6 hours. Majority of the cases lower limb vessels were injured (64.05%). Among the associated injuries combine orthopedic & soft tissue injuries were most common (60.58%). Among the vascular procedures antilogous venous graft (42.39%) followed by end to end anastomosis (27.79%) were in majority of the cases. In case of extremity vascular injury limb amputation rate was 35.40%. This morbidity can be reduced by improvement of road safely measures, encouraging doctors to vascular surgery specialty and effective training of orthopedic & general surgeons in the management of extremity vascular injury till the availability of vascular surgeons for provision of vascular services in remote areas.Bangladesh Heart Journal 2021; 36(1) : 32-37
在外科实践中,血管损伤的处理是具有挑战性的。血管损伤在发达国家得到了很好的解决,但在像我们这样的发展中国家,血管外科医生缺乏,大量受害者未能及时到达专科医生那里,结果失去了四肢或生命。为了观察发展中国家血管损伤处理的模式和结果,本回顾性研究在孟加拉国达卡国立心血管疾病研究所血管外科进行。所有存活的血管损伤患者均被纳入研究。年龄、性别、损伤原因、受损伤血管节段、相关损伤、损伤后时间、血管手术和术后并发症等数据均取自该科的记录并进行分析。在2174例血管损伤患者中,11例在复苏时死亡,52例在转诊到其他医院处理相关损伤后没有回来。患者以年轻男性居多,以道路交通事故居多(91.50%)。大多数患者(53.60%)在6小时后出现。下肢血管损伤占多数(64.05%)。在相关损伤中,以骨科和软组织损伤最为常见(60.58%)。血管手术中以抗原性静脉移植(42.39%)为主,其次为端端吻合(27.79%)。四肢血管损伤截肢率为35.40%。通过改善道路安全措施,鼓励医生进入血管外科专业,对骨科和普通外科医生进行有效的培训,以管理四肢血管损伤,直到有血管外科医生在偏远地区提供血管服务,可以减少这种发病率。孟加拉国心脏杂志2021;36(1): 32-37
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引用次数: 0
Obesity Paradox in Short-Term Clinical Outcomes After Percutaneous Coronary Interventions 经皮冠状动脉介入治疗后短期临床结果的肥胖悖论
Pub Date : 2021-09-20 DOI: 10.3329/bhj.v36i1.55511
M. Siddiqui, P. Karmakar, N. Alam, Mizanur Rahman, P. Karmaker, M. Ahsan, Anup Kumar Howlader, Fahdia Afroz, Chowdhury Md Kudrat EKhuda, Abhijit Roy
Background: The “obesity paradox”, a counterintuitive decrease in morbidity and mortality with increasing body mass index (BMI), has been shown in patients when acute cardiovascular decompensation occurs. However, whether this phenomenon exists in patients undergoing percutaneous coronary intervention (PCI) is not well known. The existence of obesity paradox and its impact on short-term clinical outcomes after PCI have not been thoroughly investigated, especially in Bangladesh.Methods: This cross-sectional observational study was conducted at National Institute of Cardiovascular Diseases, Dhaka, in 100 patients who underwent PCI. They were divided in two groups on the basis of BMI of Asian ethnicity: Group I (BMI < 23 kg/m2) and Group II (BMI <23.0 kg/m2). Short-term in-hospital outcomes after PCI were observed and recorded.Results: Acute left ventricular failure (LVF) was found to be statistically significant between groups (p < 0.01) being higher in Group-I. The difference of mean duration of hospital stay (LOS) after PCI was higher in the same group which was statistically significant (p < 0.01). Diabetes mellitus and dyslipidemia were found to be the independent predictors for developing adverse in hospital outcome (OR= 1.68 and 1.46; 95% CI = 1.25 – 2.24 and 1.16 – 1.83; p = 0.018 and 0.040, respectively). BMI was inversely associated with in-hospital outcomes after PCI (OR = 0.95; 95% CI = 0.91 – 0.98; p = 0.007).Conclusion: The results of the study uphold the phenomenon of the “obesity paradox” following PCI. The underweight and normal weight people are at greater risk to experience short-term in-hospital adverse clinical outcomes than overweight and obese people after PCI.Bangladesh Heart Journal 2021; 36(1): 1-8
背景:在急性心血管失代偿发生的患者中已经发现了“肥胖悖论”,即发病率和死亡率随体重指数(BMI)的增加而下降。然而,这种现象是否存在于经皮冠状动脉介入治疗(PCI)的患者中尚不清楚。肥胖悖论的存在及其对PCI术后短期临床结果的影响尚未得到彻底调查,特别是在孟加拉国。方法:本横断面观察性研究在达卡国立心血管疾病研究所进行,纳入100例接受PCI治疗的患者。根据亚洲种族的BMI分为两组:I组(BMI <23 kg/m2)和II组(BMI <23.0 kg/m2)。观察并记录PCI术后的短期住院结果。结果:急性左心室衰竭(LVF)发生率组间比较有统计学意义(p < 0.01),以ⅰ组较高。同一组PCI术后平均住院时间(LOS)差异较高,差异有统计学意义(p < 0.01)。糖尿病和血脂异常是发生不良住院结果的独立预测因素(OR= 1.68和1.46;95% CI = 1.25 - 2.24和1.16 - 1.83;P分别= 0.018和0.040)。BMI与PCI术后住院预后呈负相关(OR = 0.95;95% ci = 0.91 - 0.98;P = 0.007)。结论:本研究结果支持PCI术后“肥胖悖论”现象。与超重和肥胖人群相比,体重过轻和正常人群在PCI术后出现短期住院不良临床结果的风险更大。孟加拉国心脏杂志2021;36 (1): 1 - 8
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引用次数: 0
Professor Abul Hossain Khan Chowdhury (18/02/1954-20/07/2020) Abul Hossain Khan Chowdhury教授(18/02/1954-20/07/2020)
Pub Date : 2021-09-20 DOI: 10.3329/bhj.v36i1.55723
Khalequzzaman
Abstract not available Bangladesh Heart Journal 2021; 36(1): 67
孟加拉心脏杂志2021;36 (1): 67
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引用次数: 0
Evaluation of Safety and Efficacy of Combined Low Dose Aspirin and Warfarin Following Mechanical Heart Valve Replacement for Mitral Valve Disease 机械心脏二尖瓣置换术后低剂量阿司匹林联合华法林的安全性和有效性评价
Pub Date : 2021-09-20 DOI: 10.3329/bhj.v36i1.55514
Md Sorower Hossain, Istiaq Ahmed, S. Raha, S. Biswas, Md. Kamrul Hasan
Introduction: Warfarin is recommended following mechanical valve replacement to prevent thromboembolic complications. A combination of warfarin and aspirin may further reduce thromboembolic events in these patients. This study was designed to evaluate safety and efficacy of combined low dose aspirin and warfarin therapy following mechanical mitral valve replacement.Materials and Methods: Purposively selected 99 patients who underwent mechanical mitral valve replacement were divided into two groups. Patients of Group A (n=50) received combined low dose aspirin (75mg) and warfarin. Patients of Group B (n=49) received conventional dose of warfarin alone. International normalized ratio (INR) was targeted 1.8-2.4 for group A Patients and 2.5-3.5 for group B Patients. Post-operatively INR, thromboembolic events, anti-coagulation related haemorrhage and other morbidity and mortality were registered in both groups.Result: Patients were followed up postoperatively for 9 months. The mean dose of warfarin in group A and group B was 4.36 ± 0.31 mg and 5.57±0.52 mg respectively (p<0.001). The overall mean INR of two groups of patients were statistically different (P<0.001) with low INR in group A (2.19±0.13) patients compared to group B (3.03±0.31). The thromboembolic events in group A (0.02/patient year) were lower than those in group B (0.08/Patient year). There was no statistically significant (p=0.362) difference in bleeding episodes between two groups but data indicate proportion of minor bleeding manifestations were higher in patients treated with warfarin plus aspirin group.Conclusion: Following mechanical mitral valve replacement, a combination of aspirin (75mg) and low dose warfarin with an aim to maintain INR between 1.8 and 2.4 (lower than recommended 2.5-3.5) may provide satisfactory outcomes in term of thrombosis, embolism and bleeding without increase in mortality.Bangladesh Heart Journal 2021; 36(1): 24-31
简介:推荐在机械瓣膜置换术后使用华法林以预防血栓栓塞并发症。华法林和阿司匹林联合用药可进一步减少这些患者的血栓栓塞事件。本研究旨在评价机械二尖瓣置换术后低剂量阿司匹林和华法林联合治疗的安全性和有效性。材料与方法:选择99例机械二尖瓣置换术患者分为两组。A组患者(50例)联合小剂量阿司匹林(75mg)和华法林。B组49例患者单独给予常规剂量华法林治疗。国际标准化比值(INR)指标A组为1.8 ~ 2.4,B组为2.5 ~ 3.5。两组患者术后INR、血栓栓塞事件、抗凝相关出血及其他发病率和死亡率均有记录。结果:术后随访9个月。A组华法林平均剂量为4.36±0.31 mg, B组华法林平均剂量为5.57±0.52 mg (p<0.001)。两组患者总体平均INR差异有统计学意义(P<0.001), A组患者INR低(2.19±0.13),B组患者INR低(3.03±0.31)。A组血栓栓塞事件发生率(0.02例/患者年)低于B组(0.08例/患者年)。两组患者出血发生率差异无统计学意义(p=0.362),但资料显示华法林加阿司匹林组患者出现轻微出血的比例较高。结论:机械二尖瓣置换术后,联合使用阿司匹林(75mg)和低剂量华法林,目的是将INR维持在1.8 - 2.4之间(低于推荐的2.5-3.5),可能在血栓形成、栓塞和出血方面提供满意的结果,而不会增加死亡率。孟加拉国心脏杂志2021;36 (1): 24-31
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引用次数: 0
Effect of Balloon Embedded Bifurcating Stenting with Single Stent Strategy for Side Branch Protection 单支架球囊埋置分岔支架对侧支保护的效果
Pub Date : 2021-09-20 DOI: 10.3329/bhj.v36i1.55513
Bishnu Pada Saha, M. Uddin, S. Hashem, Priyanka Adhikary, Mohammad Arifur Rahman, C. M. K. E Khuda, S. Shahriar, M. Hasan, Mizanur Rahman Majumder, F. Sultana, Whaiduzzaman Jewel
Background: Intervention for bifurcation lesions is associated with increased risk of adverse events and includes acute side branch (SB) occlusion during main branch (MB) stenting. This acute occlusion of side branch can often be catastrophic for the patient. We here in describe our experience in National Institute of Cardiovascular Diseases and Hospital (NICVD), Dhaka, Bangladesh with a technique which can be incorporated into bifurcation stenting to reduce or almost eliminate the incidence of side branch occlusion or catastrophe.Methods: A prospective, observational, non-blinded study in patients from a single tertiary referral cardiac center National Institute of Cardiovascular Diseases & Hospital (NICVD), Dhaka, Bangladesh. Patients with an indication for percutaneous coronary intervention (PCI) of a denovo bifurcation lesion were screened. The study included 51 patients who underwent coronary angiogram in our institution and had bifurcation lesions suitable for single stent strategy between March 2017 to September 2018.Results: 51 patients with bifurcation lesion were included in the study and underwent a balloon embedded bifurcation stenting with a semi inflated balloon placed across the SB ostium. Angiographic success was achieved in all the patients but procedural success was achieved in 88.2% of the patients. TIMI 3 flow of main branch (MB) was achieved 96.08% and side branch (SB) was achieved 88.2%. Incidence of dissection was 5.9%, acute occlusion of SB was 2.0% and MACE was 3.9%. Mean fluoroscopy time and contrast volume was similar to that of conventional bifurcation stenting. The jailed SB balloon and wire could be successfully removed in all patients.Conclusion: The present study suggests that balloon embedded bifurcation stenting with a semi inflated balloon to protect the SB is feasible, with minimal procedural adverse events and successful in minimizing or almost eliminating the incidence of acute side branch occlusion or dissection as well as MACE.Bangladesh Heart Journal 2021; 36(1): 17-23
背景:分叉病变的干预与不良事件的风险增加有关,包括主支(MB)支架置入期间急性侧支(SB)闭塞。这种急性侧支闭塞对病人来说往往是灾难性的。我们在此描述我们在孟加拉国达卡国家心血管疾病和医院研究所(NICVD)的经验,该技术可以纳入分支支架置入,以减少或几乎消除侧支闭塞或灾难的发生率。方法:一项前瞻性、观察性、非盲性研究,研究对象为来自孟加拉国达卡国家心血管疾病与医院研究所(NICVD)单一三级转诊心脏中心的患者。筛选有经皮冠状动脉介入治疗(PCI)指征的患者。本研究纳入了51例2017年3月至2018年9月期间在我院行冠状动脉造影且存在适合单支架治疗的分叉病变的患者。结果:51例分叉病变患者被纳入研究,并接受了球囊埋置分叉支架,半充气球囊放置在SB口。所有患者均获得血管造影成功,但手术成功率为88.2%。主支路(MB)和侧支路(SB)的TIMI 3流量分别达到96.08%和88.2%。夹层发生率为5.9%,急性SB闭塞发生率为2.0%,MACE发生率为3.9%。平均透视时间和造影剂体积与传统支架术相似。在所有患者中,囚禁的SB球囊和金属丝均可成功移除。结论:本研究提示球囊内埋分岔支架采用半充气球囊保护骶椎板是可行的,其手术不良事件最小,成功地减少或几乎消除了急性侧支闭塞或剥离以及MACE的发生率。孟加拉国心脏杂志2021;36 (1): 17-23
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引用次数: 0
The Anesthesia & Anesthetists of the First Open Heart Surgery of Bangladesh 孟加拉第一例心脏直视手术的麻醉及麻醉师
Pub Date : 2021-09-20 DOI: 10.3329/bhj.v36i1.55518
Suman Nazmul Hosain, F. Amin, S. Ferdous
Although a few closed heart operations were performed in the late 1960s, well organized approach to open heart surgery began in Bangladesh only after establishment of Institute of Cardiovascular Diseases (ICVD) in 1978. A Japanese team of surgeons, anesthetists, nurses and technicians provided extensive support in capacity building of the local human resources. Ultimately the first open heart surgery of Bangladesh, the direct closure of Atrial Septal Defect of an 18 year old college student, was performed on 18th September 1981. It was great news of that time. People came to know about the success story of the ICVD director then Colonel M Abdul Malik, a renowned cardiologist cum team leader and the Bangladeshi surgeon duo Dr M Nabi Alam Khan and Dr S R Khan. But somehow the anesthetists, an important part of the team were out of focus and have been forgotten over time. Led by Prof Khalilur Rahman, the anesthetist team of the day included Dr Nurul Islam, Dr Abdul Hadi, Dr Delowar Hossain, Dr A Y F Ellahi Chowdhury and Dr Monir Hossain. This article is an attempt to remind their contribution and expressing respect and gratitude to the anesthetists of that pioneering team.Bangladesh Heart Journal 2021; 36(1) : 55-60
虽然在1960年代末进行了一些心脏闭合手术,但是在1978年建立心血管疾病研究所之后,孟加拉国才开始有组织的心脏直视手术。一支由外科医生、麻醉师、护士和技术人员组成的日本团队为当地人力资源的能力建设提供了广泛支持。1981年9月18日,孟加拉国进行了第一次心脏直视手术,对一名18岁的大学生进行了房间隔缺损直接封闭手术。这是当时的大好消息。人们开始了解到当时的ICVD主任M Abdul Malik上校,著名心脏病专家兼团队负责人,以及孟加拉国的两位外科医生M Nabi Alam Khan和S R Khan的成功故事。但不知何故,麻醉师,团队的重要组成部分,失去了焦点,随着时间的推移被遗忘了。当天的麻醉师小组由Khalilur Rahman教授领导,包括Nurul Islam医生、Abdul Hadi医生、Delowar Hossain医生、A Y F Ellahi Chowdhury医生和Monir Hossain医生。这篇文章试图提醒他们的贡献,并对这支先锋团队的麻醉师表示敬意和感谢。孟加拉国心脏杂志2021;36(1): 55-60
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引用次数: 0
Clinical, Electrocardiographic and Echocardiographic Profile of Ischemic Cardiomyopathy: An analysis of 100 cases. 缺血性心肌病100例临床、心电图及超声心动图分析。
Pub Date : 2021-04-07 DOI: 10.3329/BHJ.V35I2.52898
Mainul Islam, M. A. Ali, U. H. Ferdaushi, S. Nabi, Sayeedur Rahman Khan, Shariful Islam, H. Mahmoud
Background: Ischemic heart disease (IHD) is one of the leading cause of morbidity and mortality worldwide. Ischemic cardiomyopathy (ICM) is a delayed complication of IHD that arises as dilated cardiomyopathy with depressed ventricular function, which cannot be attributed entirely to coronary artery obstruction or ischemic injury. Objectives: To evaluate the clinical, electrocardiographic and echocardiographic profile of patients presenting with ischemic cardiomyopathy. Methods: In this cross sectional observational study 100 patients of ischemic cardiomyopathy admitted in hospital or visited OPD in NICVD, Dhaka from March’15 to Sept’15 were studied. Enrollment of the patients were done after fulfilling the inclusion and exclusion criteria. Clinical, electrocardiographic and echocardiographic data were collected then data analysis was done. Results: Data analysis of 100 patients was showed age range was 40-80 years and mean age was 61.4±7.9 years. 79% subjects were male. Most common symptoms were dyspnea (93%), chest pain(73%), palpitation (39%) and edema (23%). Most patients were in NYHA functional class lV (43%). 64% cases had history of anterior myocardial infarction (MI), 22% had inferior MI, 25% had H/O PTCA and 7% had CABG. 71% subjects had tachycardia, 65% had lungs basal rales, 56% had systolic blood pressure below 100 mmhg and 25% had edema. ECG findings was as follows sinus rhythm (85%), Sinus tachycardia 71%, AF 15%, LBBB 34%, RBBB 12%, pathological Q in anterior surface 65% and inferior surface 21%, non specific ST-T changes 41% and PVCs was found in 17%.On echocardiography ,anterior wall hypokinesia was seen in 52% and global hypokinesia in 43%. Mean left ventricular ejection fraction (LVEF) was 31±5.9% and mean left ventricular internal diastolic diameter (LVIDd) was 6.5±0.4 cm. (59%) subjects had mitral regurgitation (MR) grade-l and 20% had MR grade-ll. Conclusion: The clinical presentation of ischemic cardiomyopathy varies from patient to patient. Severity of symptoms correlates with severity of left ventricular systolic dysfunction, left ventricular diameter and mitral regurgitation grade . Anterior Myocardial infarction has more chance to develop ischemic cardiomyopathy. Bangladesh Heart Journal 2020; 35(2) : 121-127
背景:缺血性心脏病(IHD)是全球发病率和死亡率的主要原因之一。缺血性心肌病(ICM)是IHD的一种迟发性并发症,表现为扩张性心肌病伴心室功能下降,不能完全归因于冠状动脉阻塞或缺血性损伤。目的:探讨缺血性心肌病患者的临床、心电图和超声心动图特征。方法:对2015年3月至2015年9月在达卡NICVD住院或门诊就诊的100例缺血性心肌病患者进行横断面观察研究。在满足纳入和排除标准后进行患者入组。收集临床、心电图、超声心动图资料并进行数据分析。结果:100例患者资料分析,年龄40 ~ 80岁,平均年龄61.4±7.9岁。79%的受试者为男性。最常见的症状是呼吸困难(93%)、胸痛(73%)、心悸(39%)和水肿(23%)。大多数患者为NYHA功能级lV(43%)。64%有前路心肌梗死史,22%有下路心肌梗死,25%有H/O PTCA, 7%有冠脉搭桥。71%的受试者有心动过速,65%的受试者有肺基底音,56%的受试者收缩压低于100 MMHG, 25%的受试者有水肿。心电图表现如下:窦性心律85%,窦性心动过速71%,房颤15%,LBBB 34%, RBBB 12%,前表面病理Q 65%,下表面病理Q 21%,非特异性ST-T改变41%,室性早搏17%。超声心动图显示52%的患者出现前壁运动障碍,43%的患者出现全身运动障碍。平均左室射血分数(LVEF) 31±5.9%,平均左室舒张内径(LVIDd) 6.5±0.4 cm。(59%)受试者二尖瓣返流(MR)为一级,20%为二级。结论:缺血性心肌病的临床表现因人而异。症状的严重程度与左心室收缩功能障碍的严重程度、左心室直径和二尖瓣返流等级相关。前路心肌梗死更容易发展为缺血性心肌病。孟加拉国心脏杂志2020;35(2): 121-127
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引用次数: 0
Successful Management of a Giant Mycotic Coronary Artery Aneurysm Develeped after Multivessel PCI with Drug-Eluting Stent 药物洗脱支架多支冠脉PCI术后巨大霉菌性冠状动脉瘤的成功治疗
Pub Date : 2020-09-15 DOI: 10.3329/bhj.v35i1.49145
Muhammad Salim Mahmod, Mohammad Arifur Rahman, Nuruddin Mohammod Zahangir, R. Basak, Mohammad Maknunur Rahman Khan
Coronary artery stent infection has been reported with both bare metal stent and drug eluting stent and can present as mycotic coronary artery aneurysm, pseudoaneurysm. myocardial abscess, pericarditis or exudative effusion. Infection at the site of coronary stent implantation is rare and is believed to result typically from either direct stent contamination at the time of delivery or transient bacteraemia from access site. Recently, several case reports of pseudoaneurysm formation after DES implantation have been reported in the literature. We describe the successful surgical management of giant mycotic pseudoaneurysm of RCA presenting as fever of unknown origin with AMI (inferior) three months after multivessel PCI in LAD & RCA with DES in radial route. This report illustrates the importance of early detection and prompt management of these rare coronary pseudoaneurysms, which is a highly lethal condition. At three months follow-up after surgery, the patient was asymptomatic with fair LVEF 58% Bangladesh Heart Journal 2020; 35(1) : 66-70
裸金属支架和药物洗脱支架均有冠状动脉支架感染的报道,并可表现为真菌性冠状动脉动脉瘤、假性动脉瘤。心肌脓肿、心包炎或渗出性积液。冠状动脉支架植入部位的感染是罕见的,通常被认为是由于支架在运送时的直接污染或暂时性的细菌血症。最近,文献报道了几例DES植入后假性动脉瘤形成的病例。我们描述了在LAD和RCA桡动脉行DES的多血管PCI后三个月,以不明原因发热伴AMI(下)为表现的RCA巨大真菌性假性动脉瘤的成功手术处理。本报告说明早期发现和及时处理这些罕见冠状假性动脉瘤的重要性,这是一种高度致命的疾病。术后随访3个月,患者无症状,LVEF正常58%孟加拉心脏杂志2020;35(1): 66-70
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引用次数: 2
In-hospital Outcome of Percutaneous Coronary Intervention among Very Elderly Patients with Ischemic Heart Disease in a Dedicated Cardiac Hospital 心脏专科医院高龄缺血性心脏病患者经皮冠状动脉介入治疗的住院疗效
Pub Date : 2020-09-15 DOI: 10.3329/bhj.v35i1.49144
Mohammad Arifur Rahman, Afzalur Rahman, Mohammd Mahbubur Rahman, Farhana Ahmed, Md. Kamrul Hasan, J. Farjana, Md Azizur Rahaman Majumder, Ahmed Mamunul Huq, Atikur Rahman
Background: Cardiovascular disease, and ischemic heart disease (IHD), is a major cause of morbidity and mortality in the very elderly patients (>80 years) worldwide. These patients represent a rapidly growing cohort presenting for percutaneous coronary intervention (PCI), now constituting more than one in five patients treated with PCI in real-world practice. Furthermore, they often have greater ischemic burden than their younger counterparts, suggesting that they have greater scope of benefit from coronary revascularization therapy. The elderly usually has higher prevalence of co morbidities and more often experience complications during and after revascularization procedures. Our aim was to evaluate clinical outcomes of PCI in patients older than 80 years, compared to their younger counterparts. Materials and methods: From July 2017 to July 2018 we included 212 patients with IHD purposively in Cardiology department of National Institute of Cardiovascular Diseases undergone PCI who were divided into 2 groups according to age: e” 80 years (n = 74) and < 80 years (n = 138). Baseline clinical characteristics, indications for coronary intervention, in hospital outcomes were obtained. Study endpoint were Renal impairment, MI, LVF, emergency revascularization and death. Results: Very elderly patients were more frequently male (86%) and nonsmoker at present (41% vs. 63%, p=0.003), had higher prevalence of hypertension (60% vs. 50%, p<0.13), and more often presented with NSTEMI (54% vs. 23%, p<0.001). Elderly group had higher incidence of TVD and LM disease (36% vs. 26% and 9.5% vs. 2.9%, p=0.07) and more incidence of ostial (16.2% vs.5.1%,p=0.007) and calcified lesions (31.1% vs. 14.5%, p=0.004). Procedural success (TIMI III) were high in both groups, but still lower in the elderly as compared to younger group (95% vs. 97%, p=0.65). Very elderly patients had higher incidence of post PCI bleeding, CIN, MI, LVF and death (9.5% vs.6.1%, 8.2% vs.3.7%, 6.8% vs.5.8%, 9.5% vs. 5.1% and 5.4%vs.3.6%,p=0.07), whereas emergency revascularization were higher in younger group (5.4% vs. 6.5%, p=0.07). Conclusion: Very elderly patients aged ≥80 years face more vascular site complications during PCI, usually have more LM and TVD with more ostial and calcified lesions in comparison with younger group. Though procedural success is similar with younger group, they face more post PCI CIN, LVF and MI. Repeat revascularization was higher in younger group. Bangladesh Heart Journal 2020; 35(1) : 61-65
背景:心血管疾病和缺血性心脏病(IHD)是世界范围内高龄患者(>80岁)发病率和死亡率的主要原因。这些患者代表了一个快速增长的接受经皮冠状动脉介入治疗(PCI)的人群,现在在现实世界中,超过五分之一的患者接受了PCI治疗。此外,他们往往比年轻人有更大的缺血负担,这表明他们从冠状动脉血运重建治疗中获益的范围更大。老年人通常有较高的合并症患病率,并且在血运重建术期间和之后更常出现并发症。我们的目的是评估80岁以上患者PCI的临床效果,并与年轻患者进行比较。材料与方法:2017年7月至2018年7月,我们在国立心血管疾病研究所心内科接受PCI治疗的IHD患者212例,按年龄分为80岁(n = 74)和80岁以下(n = 138)两组。获得基线临床特征、冠状动脉介入治疗指征和住院结果。研究终点为肾功能损害、心肌梗死、左心室充血、急诊血运重建术和死亡。结果:高龄患者多为男性(86%),目前不吸烟(41%比63%,p=0.003),高血压患病率较高(60%比50%,p<0.13),更常出现NSTEMI(54%比23%,p<0.001)。老年组TVD、LM病变发生率较高(36% vs. 26%, 9.5% vs. 2.9%, p=0.07),口部病变发生率较高(16.2% vs.5.1%,p=0.007)、钙化病变发生率较高(31.1% vs. 14.5%, p=0.004)。两组的手术成功率(TIMI III)都很高,但与年轻组相比,老年人的手术成功率仍较低(95%对97%,p=0.65)。高龄患者PCI术后出血、CIN、MI、LVF和死亡发生率较高(9.5%比6.1%、8.2%比3.7%、6.8%比5.8%、9.5%比5.1%和5.4%比3.6%,p=0.07),而年轻患者急诊血运重建术发生率较高(5.4%比6.5%,p=0.07)。结论:≥80岁高龄患者行PCI时血管部位并发症较多,LM、TVD多,口部及钙化病变多。虽然手术成功率与年轻组相似,但他们面临更多的PCI后CIN、LVF和MI,重复血运重建率更高。孟加拉国心脏杂志2020;35(1): 61-65
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引用次数: 0
Tetralogy of Fallot with Absent Pulmonary Valve Syndrome with Absent Left Pulmonary Artery - A Rare Presentation 法洛四联症合并肺动脉瓣缺失综合征并左肺动脉缺失-一种罕见的表现
Pub Date : 2020-09-15 DOI: 10.3329/bhj.v35i1.49148
A. Shamsuddin, P. Biswas, Muhammad Ishtiaque Sayeed Al Manzoo, M. Azad, Md Nurul Akhtar Hasan, Jasmin Hosain, Mohammad Sharifuzzaman Shamsuddin
Absent left pulmonary artery with Tetralogy of Fallot (TOF) with absent pulmonary valve syndrome (APVS), is a rare congenital cardiac anomaly. Here we present such a case of A 2 year 11 month old girl with cyanosis, exertional dyspnoea. Her diagnosis is confirmed by echocardiography and CT angiogram. There are very few cases have been reported till date with high postoperative mortality. Although per operative decision making was challenging regarding pulmonary valve and size of the RPA, we performed ICR with RPA reductionplasty and creation of monocuspid pulmonary valve with success. As it is a rare association and we have overcome the hindrance we came across per operatively, we are reporting this case. Bangladesh Heart Journal 2020; 35(1) : 74-77
左肺动脉缺失伴法洛四联症(TOF)合并肺动脉瓣缺失综合征(APVS)是一种罕见的先天性心脏异常。在这里,我们提出这样一个2岁11个月的女孩与紫绀,用力呼吸困难。超声心动图和CT血管造影证实了她的诊断。迄今为止报道的病例很少,术后死亡率高。尽管每次手术决策都是关于肺动脉瓣和RPA大小的挑战,但我们成功地进行了ICR和RPA复位成形术并创建了单尖瓣肺动脉瓣。由于这是一种罕见的关联,我们已经克服了我们在手术中遇到的障碍,我们报告了这个病例。孟加拉国心脏杂志2020;35(1): 74-77
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引用次数: 1
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Bangladesh Heart Journal
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