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Issues and Development in Health Research Vol. 3最新文献

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Investigation of the Knowledge and Practices of Drivers/Conductors Working in Government Buses Running Through Tricity, Chandigarh Regarding the Use of First Aid Kit 昌迪加尔政府巴士司机/售票员使用急救箱的知识及做法调查
Pub Date : 2021-08-18 DOI: 10.9734/bpi/idhr/v3/3855f
Jyoti, N. Goel, S. Prashar
Background: Road safety is a shared responsibility. Prompt first aid provision at the place of accidents can reverse unpleasant consequences of victim's health and life. Reducing risk in the world’s road traffic systems requires commitment and informed decision-making by all stakeholders- government, industry, non-governmental organizations and international agencies and the participation of people from all walks of life [1]. Methods: A cross- sectional, community- based, exploratory study was conducted for four months (Jan 2019 to Apr 2019) to assess the knowledge and practices of first aid among drivers and conductors of buses running through Tricity, Chandigarh. In this study, a total of 300 drivers and 300 conductors of buses of CTU, Haryana Roadways, Himachal Roadways and Punjab Roadways were interviewed in order to have a generalized idea about the level of awareness and practices of first aid in real-life circumstances by the government employees of buses. Results: Five hundred and seventy-five (95.8%) employees were aware of the prominent position of first aid box in buses and 197 (32.8%) employees felt safety of passenger as their foremost duty when bus meets an accident. Conclusion: The awareness and practices of first aid among drivers/conductors in saving the lives of passengers is seen comparatively more than the other studies conducted previously. But they still require more awareness and better practices to be followed.
背景:道路安全是一项共同责任。在事故发生地点及时提供急救可以扭转对受害者健康和生命造成的不愉快后果。减少世界道路交通系统的风险需要政府、行业、非政府组织和国际机构等所有利益攸关方的承诺和知情决策,需要各行各业人民的参与[1]。方法:通过为期4个月(2019年1月至2019年4月)的横断面、基于社区的探索性研究,评估昌迪加尔市Tricity公交车司机和售票员的急救知识和实践情况。在本研究中,共采访了CTU,哈里亚纳邦公路,喜马偕尔公路和旁遮普公路的300名司机和300名售票员,以便对公共汽车政府雇员在现实生活中急救意识和实践的水平有一个大致的了解。结果:575名(95.8%)员工意识到急救箱在公交车上的突出位置,197名(32.8%)员工在公交车发生事故时认为乘客的安全是他们的首要职责。结论:司机/售票员在挽救乘客生命方面的急救意识和实践比之前进行的其他研究要多。但他们仍然需要更多的意识和更好的做法来遵循。
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引用次数: 0
Circuit Training and Sarcopenic Obesity 循环训练和肌肉减少性肥胖
Pub Date : 2021-08-18 DOI: 10.9734/bpi/idhr/v3/4079f
Won-Sang Jung, Hun-Young Park
Sarcopenic obesity is a physiological issue caused by ageing that worsens the elderly's quality of life by reducing bodily function, increasing body fat, and decreasing muscle mass. Furthermore, it leads to a variety of social and economic issues, including the progression and contraction of a chronic condition, increased health-care expenses, and a rise in the prevalence or mortality rate. It has an adverse influence on metabolic illness symptoms such as decreased body function and physical strength, blood lipids, and body inflammation and hormones. Exercise therapy is currently recommended as a treatment for elderly health concerns. Regular aerobic exercise is effective in increasing body function and muscle mass, and regular resistance exercise is effective in improving body function and muscle mass. Resistance exercise has recently been highlighted in obese elderly persons in order to improve muscular function and prevent falls. Resistance exercise, on the other hand, has several drawbacks, such as the risk of injury, the inability to exercise in a specific location, and the inability to reduce obesity, so a new exercise approach for the sarcopenic obese elderly should be offered. The circuit exercise with weight bearing offers a lower risk of injury, and it can be done in a group setting without regard to cost or location, and it can be done continuously with interest. Circuit training is also advised for the elderly because it improves body composition and a variety of physical characteristics in a very short period of time. Despite these positive effects, the studies reported so far are limited. Future research is needed to confirm the effects of different intensities, frequency, time, and duration of circuit exercise in sarcopenic obesity elderly. Therefore, this review summarizes recent research evidences suggesting that the improvement of muscle mass and body fat mass via circuit exercise program might be a valuable and viable “sarcopenic obesity therapeutic modality.
肌少性肥胖是一种由衰老引起的生理问题,它会降低老年人的身体功能,增加身体脂肪,减少肌肉质量,从而恶化老年人的生活质量。此外,它还导致各种社会和经济问题,包括慢性病的恶化和收缩、保健费用的增加以及患病率或死亡率的上升。它对代谢疾病症状有不良影响,如身体功能和体力下降、血脂、身体炎症和激素。运动疗法目前被推荐作为老年人健康问题的治疗方法。有规律的有氧运动对提高身体机能和肌肉质量是有效的,有规律的阻力运动对提高身体机能和肌肉质量是有效的。为了改善肌肉功能和防止跌倒,抗阻运动最近在肥胖老年人中得到了强调。另一方面,阻力运动存在损伤风险、无法在特定位置运动、无法减少肥胖等弊端,因此应该为肌肉减少型肥胖老年人提供一种新的运动方式。负重循环运动的受伤风险较低,可以在群体环境中进行,不需要考虑成本或地点,而且可以带着兴趣连续进行。循环训练也适合老年人,因为它可以在很短的时间内改善身体成分和各种身体特征。尽管有这些积极的影响,迄今为止报道的研究是有限的。需要进一步的研究来证实不同强度、频率、时间和持续时间的循环运动对肌肉减少型肥胖老年人的影响。因此,本文综述了最近的研究证据,表明通过循环运动计划改善肌肉质量和体脂质量可能是一种有价值和可行的“肌肉减少型肥胖”治疗方式。
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引用次数: 0
Nanodontics- A New Horizon in Dentistry 纳米牙齿学——牙科的新领域
Pub Date : 2021-08-18 DOI: 10.9734/bpi/idhr/v3/12547d
Sunantha Selvaraj, D. Jayachandran
Nanodentistry is the application of nanotechnology in dentistry. The arrival of 21st century, suddenly focused on dentistry a new paradigm regarding expected standard for state-of the- art-patient care. Over last few years truly remarkable progress has been made in such diverse areas as proteomics, gene therapy, vaccine development, stem cells, tissue engineering nanotechnology and drug development through combinatorial chemistry. Although much of this progress has been at the preclinical, translational research stage and some notable advances have already entered the clinic. Nanodentistry is the future of dentistry in which every procedure will be performed using equipment and devices based on nanotechnology. All diagnoses and treatments will be given using nanoscale-structured materials and nanorobots. These materials and devices will have the ability to accurately diagnose a problem and provide solution in the shortest possible time and precisely. Nanotechnology makes it possible to construct materials which have longer life and very close to nature. Nanoproducts made for various dental procedures has more hardness, elasticity and strength with increased shelf life than the ones which were used in conventional practice. Furthermore, they will have better appearance in terms of color, texture and esthetic appeal.
纳米牙医学是纳米技术在牙科中的应用。21世纪的到来,突然集中在牙科一个新的范式,关于国家的艺术护理的预期标准。在过去几年中,在蛋白质组学、基因治疗、疫苗开发、干细胞、组织工程、纳米技术和通过组合化学开发药物等不同领域取得了真正显著的进展。虽然大部分进展还处于临床前、转化研究阶段,但一些显著的进展已经进入临床。纳米牙科是牙科的未来,其中每个程序都将使用基于纳米技术的设备和装置来执行。所有的诊断和治疗都将使用纳米结构材料和纳米机器人。这些材料和设备将能够在尽可能短的时间内准确诊断问题并提供解决方案。纳米技术使人们有可能制造出寿命更长、非常接近自然的材料。用于各种牙科手术的纳米产品具有更高的硬度,弹性和强度,并且比传统实践中使用的产品具有更长的保质期。此外,他们将有更好的外观在颜色,质地和审美情趣。
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引用次数: 1
NRCT Clinical Study in to Identify Acetaminophen-Induced Liver Injury Mechanism 对乙酰氨基酚致肝损伤机制的NRCT临床研究
Pub Date : 2021-08-18 DOI: 10.9734/bpi/idhr/v3/12128d
Yawo M Akrodou
Acetaminophen (APAP) (N-acetyl-p-aminophenol) is a chemical molecule used to relieve pain and lower fever in paracetamol medications. The Food and Drug Administration (FDA) advisory group warned in June 2009 about the risk of APAP overdose due to its side effects, which include drug-induced liver disease. In addition, the FDA has begun multicenter non-interventional case-control studies to collect data on APAP toxicity biomarkers in children and adolescents. The National Center for Toxicological Research (NCTR), which is part of the FDA, coordinates the execution of APAP clinical trials in collaboration with other health institutes (hospitals, universities, and clinical centres) around the United States. The goal of these clinical trials is to gather enough data to create a list of biomarkers connected to acetaminophen toxicity that can be matched with specific adduct proteins; this information can then be used to examine and predict future hazards in children who are taking acetaminophen.
对乙酰氨基酚(n -乙酰基-对氨基酚)是一种化学分子,在扑热息痛药物中用于缓解疼痛和退烧。美国食品和药物管理局(FDA)咨询小组在2009年6月警告说,由于APAP的副作用,包括药物性肝病,APAP过量使用的风险很大。此外,FDA已经开始了多中心非干预性病例对照研究,以收集儿童和青少年APAP毒性生物标志物的数据。FDA下属的国家毒理学研究中心(NCTR)与美国各地的其他卫生机构(医院、大学和临床中心)合作,协调APAP临床试验的执行。这些临床试验的目标是收集足够的数据,以创建与对乙酰氨基酚毒性相关的生物标志物列表,这些生物标志物可以与特定的加合物蛋白相匹配;这些信息可以用来检查和预测服用对乙酰氨基酚的儿童未来的危害。
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引用次数: 0
Description of Psychological Distress and Coping Style in HIV-infected Patients hiv感染者心理困扰及应对方式描述
Pub Date : 2021-08-18 DOI: 10.9734/bpi/idhr/v3/12003d
I. Marincu, Iulia Vidican, F. Bratosin, O. Suciu, L. Ţîrnea
Background: The advancement of HIV infection is linked to a great deal of psychological discomfort. The goal of this study was to see if there was a correlation between psychological distress, depression, coping style, and immunological activation in HIV-positive patients. Objectives: In this study, we analyzed current understandings of depression as well as psychological distress among HIV-infected individuals in West Romania. Materials and Methods: A total of 110 HIV-positive individuals from Timisoara's Clinic of Infectious Diseases took part in the study. Each patient performed a self-report that included the Beck depression inventory (BDI), the perceived stress scale (PSS), and the brief orienting to the problems experienced (Brief- COPE) scale.CD4 cell counts and viral load were used to track immune activation (VL). Results: BDI scores indicating moderate depression were found in 26% of the study participants, whereas severe depression was found in 3%. Furthermore, 24.5 percent of the patients had PSS values above 10.Higher levels of depression correlated with lower CD4 cells counts (r = 0.275, p<0.004) and with higher VL (r = 0.211, p < 0.027).  Self-blaming had a negative relationship with CD4, whereas behavioural disengagement had a good relationship with VL. Conclusion: Increased depression, combined with increased levels of perceived psychological distress, leads to maladaptive coping patterns linked to HIV infection progression.
背景:HIV感染的进展与大量的心理不适有关。这项研究的目的是观察hiv阳性患者的心理困扰、抑郁、应对方式和免疫激活之间是否存在相关性。目的:在这项研究中,我们分析了目前对西罗马尼亚艾滋病毒感染者中抑郁症和心理困扰的理解。材料和方法:共有110名来自蒂米什瓦拉传染病诊所的艾滋病毒阳性个体参加了这项研究。每位患者进行自我报告,包括贝克抑郁量表(BDI)、感知压力量表(PSS)和所经历问题的简要导向量表(brief - COPE)。CD4细胞计数和病毒载量用于跟踪免疫激活(VL)。结果:BDI评分显示,26%的研究参与者患有中度抑郁症,而3%的研究参与者患有重度抑郁症。此外,24.5%的患者PSS值在10以上。抑郁程度越高,CD4细胞计数越低(r = 0.275, p<0.004), VL越高(r = 0.211, p< 0.027)。自责与CD4呈负相关,行为脱离与VL呈正相关。结论:抑郁症的增加,加上感知到的心理困扰水平的增加,导致与HIV感染进展相关的适应不良的应对模式。
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引用次数: 0
The Energy-saving Measurements of On-land Transportation in Taiwan: An Advanced Study 台湾陆上交通之节能措施研究进展
Pub Date : 2021-08-18 DOI: 10.9734/bpi/idhr/v3/3966f
Shyi-Min Lu
In this article, the optimization of energy-saving and carbon reducing measures are addressed and discussed. Transportation is one of the most important sources of income and labor for a country's economy. The progressive depletion of fossil fuels and the looming threat of global warming have had an impact on human civilizations and ecosystems in recent years. The primary goal of on-land transportation is to transport people. According to data, the total energy consumption of all passenger cars in Taiwan accounts for 70% of total on-land transport energy consumption and 50% of total energy consumption in the transportation sector.
本文就节能降碳措施的优化问题进行了探讨。交通运输是一个国家经济最重要的收入和劳动力来源之一。近年来,化石燃料的逐渐枯竭和全球变暖的威胁迫在眉睫,对人类文明和生态系统产生了影响。陆上交通的主要目的是运送人。数据显示,台湾所有乘用车的总能耗占陆地运输总能耗的70%,占交通运输总能耗的50%。
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引用次数: 0
Implementation of the Case-Based Learning (CBL) Method on Protein Energy Malnutrition in Third-Year Basic B. Sc Students of Nursing 基于案例学习(CBL)方法在护理学基础本科三年级学生蛋白质能量营养不良中的应用
Pub Date : 2021-08-18 DOI: 10.9734/bpi/idhr/v3/3854f
J. Varghese
The health service has emerged as a critical one in both its social and economic consequences. The development of this sector thus requires a focus on personnel competence and social health needs. This study aims to achieve these goals through the introduction of case based learning methodology in dealing with protein energy malnutrition related cases. This study aims to quantify improvements in subject knowledge retention as well as attitudes. This study divides students into 2 groups with one receiving traditional lecture based learning and the other being introduced to CBL methodology, results pertaining to the impact of CBL on the latter group are obtained through statistical methods like unpaired t-test and have been presented in tabular form. Overall improvement has been shown in both subject knowledge retention of students and attitudes of both students and teachers towards CBL methodology. This study aims to contribute towards revitalizing the nursing education curriculum in both teaching methodology and in directing greater attention towards social crisis points like Protein energy malnutrition care.
在其社会和经济后果方面,保健服务已成为一个关键服务。因此,该部门的发展需要注重人员能力和社会健康需求。本研究旨在透过引入个案学习方法来处理与蛋白质能量营养不良相关的个案,以达到上述目标。本研究旨在量化学科知识保留和态度的改善。本研究将学生分为两组,一组接受传统的讲座式学习,另一组接受CBL方法,CBL对后一组的影响结果通过非配对t检验等统计方法得出,并以表格形式呈现。在学生的学科知识保留和学生和教师对CBL方法的态度方面均显示出全面的改善。本研究旨在促进护理教育课程在教学方法上的更新,以及对蛋白质能量营养不良护理等社会危机点的关注。
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引用次数: 0
Study on Genome Sequencing Practices as Driving Force of Clinical Research Modernization in the Future 基因组测序实践作为未来临床研究现代化驱动力的研究
Pub Date : 2021-08-18 DOI: 10.9734/bpi/idhr/v3/3963f
Yawo M Akrodou
Genome sequencing is one of the latest technologies to be introduced into medical practices for disease diagnostic and clinical trials for drugs discovery. It is often used in the practices of genomic medicine, to process and analyze genes and markers information to diagnose and treat disease. Specifically, genomic medicine uses DNA and RNA platform sequencing technologies to analyze human genome to detect, mutation, molecular abnormalities with clear clinical significances that may be associated to rare genetic diseases. The Human Genome Sequencing Project, which found around 35,000 genes in sequences of more than 3 billion human DNA and RNA chemical bases, was completed in 2003 with the use of these genomic sequencing platforms (first- and second-generation sequencing technologies). This cleared the door for genomic medicine, allowing researchers to conduct translational genomic clinical trials, which have advanced the clinical trial process in a variety of ways.
基因组测序是医学实践中用于疾病诊断和药物发现临床试验的最新技术之一。它经常用于基因组医学的实践,处理和分析基因和标记信息,以诊断和治疗疾病。具体而言,基因组医学利用DNA和RNA平台测序技术对人类基因组进行分析,以检测可能与罕见遗传病相关的具有明确临床意义的突变、分子异常。人类基因组测序计划于2003年使用这些基因组测序平台(第一代和第二代测序技术)完成,该计划在超过30亿个人类DNA和RNA化学碱基的序列中发现了大约35,000个基因。这为基因组医学打开了大门,使研究人员能够进行转化基因组临床试验,从而以多种方式推进了临床试验进程。
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引用次数: 0
Conduction Disturbances and Permanent Cardiac Pacing after Transcatheter Aortic Implantation (TAVI) - An Update Overview 经导管主动脉植入术(TAVI)后的传导障碍和永久性心脏起搏-最新综述
Pub Date : 2021-08-18 DOI: 10.9734/bpi/idhr/v3/12530d
A. M. Júnior, Marcelo de Freitas Ribeiro
Aortic valve replacement is a routine procedure with acceptable risk. In some cases, mortality is high, contraindicating the procedure. The minimally invasive transcatheter aortic valve implantation seems to be an alternative, reducing morbidity and mortality. In this procedure, a bioprosthetic valve is introduced through a catheter and fixed within the injured native aortic valve. Even though the technique is considered comparatively safe, the risks of complications exist and they that have been established by individuals after the technique, for example new-onset permanent left bundle branch block (LBBB) and the need for permanent cardiac pacing implantation. A systematic review of literature of PUBMED was carried out using “10 years” and “free full texts” as filters, containing the terms “TAVI,” “pacing,” and “complications,” finding a total of eight articles. Other databases, such as SCIELO, Google Scholar and MEDLINE were used to give background, consistency, and profundity to the text. The implantation of aortic valve prosthesis per catheter seems to be a valid modality for high–surgical risk patients with aortic stenosis. The results of this series of patients suggest that the need for a definitive pacemaker after endovascular treatment is not inexorable and is not easily predicted by the risk factors described so far. TAVI is the procedure of choice considered feasible and safe. Since the site of implantation of the valve prosthesis is close to septal cardiac structures with important function, conduction disorders are frequent, requiring cautious surveillance for at least seven days after the procedure. A lack of consensus and large variability in the management of conduction disturbances post-TAVR exists. Future studies need to validate the proposed algorithm and determine the role of EP studies, ambulatory continuous ECG monitoring, and prophylactic pacemaker in the management of conduction disturbance in post-TAVR patients.
主动脉瓣置换术是一项常规手术,风险可接受。在某些情况下,死亡率很高,这是手术的禁忌。微创经导管主动脉瓣植入术似乎是另一种选择,可以降低发病率和死亡率。在这个过程中,一个生物假体瓣膜通过导管引入并固定在受损的原生主动脉瓣内。尽管该技术被认为是相对安全的,但存在并发症的风险,这些风险是在技术后由个人确定的,例如新发永久性左束支阻滞(LBBB)和需要永久性心脏起搏植入。以“10年”和“免费全文”为筛选词,包含“TAVI”、“节奏”和“并发症”等术语,对PUBMED文献进行系统综述,共发现8篇文章。其他数据库,如SCIELO、Google Scholar和MEDLINE被用来提供文本的背景、一致性和深度。主动脉瓣置换术是治疗主动脉瓣狭窄高危患者的有效方法。这一系列患者的结果表明,在血管内治疗后需要一个明确的起搏器并不是不可避免的,也不容易通过目前所描述的危险因素来预测。TAVI被认为是可行和安全的手术选择。由于瓣膜假体植入位置靠近具有重要功能的心脏间隔结构,容易出现传导障碍,术后至少7天需要谨慎监测。在tavr后传导干扰的管理方面缺乏共识和很大的可变性。未来的研究需要验证所提出的算法,并确定EP研究、动态连续ECG监测和预防性起搏器在tavr后患者传导障碍管理中的作用。
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引用次数: 0
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