{"title":"Spirituality as an Effective Aid in Reducing the Mental Stress of Medical Students in India","authors":"Pulkit Johar, Harikrishnan Kodamana, Shubham Miglani","doi":"10.4103/jme.jme_130_22","DOIUrl":"https://doi.org/10.4103/jme.jme_130_22","url":null,"abstract":"","PeriodicalId":251651,"journal":{"name":"Journal of Medical Evidence","volume":"648 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120884281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Telemedicon 2022 Kerala 10th November to 12th November 2022","authors":"Meenu Singh, A. Agarwal","doi":"10.4103/jme.jme_145_22","DOIUrl":"https://doi.org/10.4103/jme.jme_145_22","url":null,"abstract":"","PeriodicalId":251651,"journal":{"name":"Journal of Medical Evidence","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126696953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tanuja Varshney, P. Singh, S. Saha, Sukdev Manna, V. Pai, Manisha Naithani, A. Mirza
Background: Rheumatoid arthritis (RA) is a systemic autoimmune disease leading to the destruction of articular cartilage and deformity of joints if not detected early. There is an unmet need to find out a highly sensitive and specific biomarker for RA. This was the first study designed in Indian setting to assess whether it can be used as a biomarker in the diagnosis of RA in the Indian population. Aim: To correlate serum Beclin1 in the pathogenesis of rheumatoid arthritis in the Indian population. Patients and Methods: Observational analytical study was conducted for 18 months at AIIMS Rishikesh, Department of Biochemistry in collaboration with the Department of Rheumatology. Beclin1 serum expression levels were estimated by the enzyme-linked immunosorbent assay and beclin1 mRNA expression was assessed by a real-time polymerase chain reaction from peripheral blood mononuclear cells (PBMCs). Beclin1 expression was compared by Mann–Whitney U-test using SPSS 22 version. Cut-off values of Beclin1 for screening of cases were analysed by receiver operating characteristic test. Results: Age- and sex-matched 38 RA patients (5 males and 33 females) and 39 controls (8 males and 31 females) were recruited in the study. Patients with the American College of Rheumatology/European League Against Rheumatism score ≥6 were recruited in this study. Serum level of beclin1 was significantly (P ≤ 0.001) lower in cases (6.30 [2.82]) compared to healthy controls (11.43 [4.62]) which were corroborated with mRNA expression. The optimal cut-off value for detecting RA cases was 7.25 with 89.7% sensitivity and 79.8% specificity. Conclusion: Beclin1 may be involved in the pathogenesis of RA and may be considered a diagnostic marker for RA cases.
{"title":"Predictive Value of Beclin1 in the Pathogenesis of Rheumatoid Arthritis in the Indian Population","authors":"Tanuja Varshney, P. Singh, S. Saha, Sukdev Manna, V. Pai, Manisha Naithani, A. Mirza","doi":"10.4103/jme.jme_48_22","DOIUrl":"https://doi.org/10.4103/jme.jme_48_22","url":null,"abstract":"Background: Rheumatoid arthritis (RA) is a systemic autoimmune disease leading to the destruction of articular cartilage and deformity of joints if not detected early. There is an unmet need to find out a highly sensitive and specific biomarker for RA. This was the first study designed in Indian setting to assess whether it can be used as a biomarker in the diagnosis of RA in the Indian population. Aim: To correlate serum Beclin1 in the pathogenesis of rheumatoid arthritis in the Indian population. Patients and Methods: Observational analytical study was conducted for 18 months at AIIMS Rishikesh, Department of Biochemistry in collaboration with the Department of Rheumatology. Beclin1 serum expression levels were estimated by the enzyme-linked immunosorbent assay and beclin1 mRNA expression was assessed by a real-time polymerase chain reaction from peripheral blood mononuclear cells (PBMCs). Beclin1 expression was compared by Mann–Whitney U-test using SPSS 22 version. Cut-off values of Beclin1 for screening of cases were analysed by receiver operating characteristic test. Results: Age- and sex-matched 38 RA patients (5 males and 33 females) and 39 controls (8 males and 31 females) were recruited in the study. Patients with the American College of Rheumatology/European League Against Rheumatism score ≥6 were recruited in this study. Serum level of beclin1 was significantly (P ≤ 0.001) lower in cases (6.30 [2.82]) compared to healthy controls (11.43 [4.62]) which were corroborated with mRNA expression. The optimal cut-off value for detecting RA cases was 7.25 with 89.7% sensitivity and 79.8% specificity. Conclusion: Beclin1 may be involved in the pathogenesis of RA and may be considered a diagnostic marker for RA cases.","PeriodicalId":251651,"journal":{"name":"Journal of Medical Evidence","volume":"90 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132200337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Leslie H blumgart","authors":"Vinay Kapoor","doi":"10.4103/jme.jme_144_22","DOIUrl":"https://doi.org/10.4103/jme.jme_144_22","url":null,"abstract":"","PeriodicalId":251651,"journal":{"name":"Journal of Medical Evidence","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132237031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jaya Agarwal, Pallavi Kumar, C. Varghese, U. Gopalakrishnan, S. Sudhindran, U. Anandh
{"title":"Aye zindagi – The show must go on!","authors":"Jaya Agarwal, Pallavi Kumar, C. Varghese, U. Gopalakrishnan, S. Sudhindran, U. Anandh","doi":"10.4103/jme.jme_149_22","DOIUrl":"https://doi.org/10.4103/jme.jme_149_22","url":null,"abstract":"","PeriodicalId":251651,"journal":{"name":"Journal of Medical Evidence","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116932148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nandita Sharma, Mahendra Singh, Y. Bahurupi, Pradeep Aggarwa
{"title":"Revised BG prasad socioeconomic status scale for the year 2022: Updation based on latest base year series 2016","authors":"Nandita Sharma, Mahendra Singh, Y. Bahurupi, Pradeep Aggarwa","doi":"10.4103/jme.jme_42_22","DOIUrl":"https://doi.org/10.4103/jme.jme_42_22","url":null,"abstract":"","PeriodicalId":251651,"journal":{"name":"Journal of Medical Evidence","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114165231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Manish Singh, M. Maurya, Ahmed Yoosuf, Shikha Nargotra, P. Pawar, Ritika Mukherjee, Archisman Mahapatro
Background: During the COVID-19 pandemic, Anganwadi workers (AWWs) were repositioned for community support, community surveillance, community awareness on infection prevention and mitigating stigma/discrimination entailing infection, going door to door. The job entailed good knowledge, attitude and practices (KAP) with regard to infection prevention and control (IPC). Aims: To assess the KAP of AWW with regard to IPC in context of COVID-19 in Lucknow district. Methods: A cross-sectional survey was conducted using Google form between 30 June and 28 July 2020. AWWs were recruited from Lucknow district irrespective of their training status; data analysis was done on 137 participants. The mean KAP score was calculated and student t-test was applied. Chi-square test was performed between categorical variables and KAP. Univariate and multivariate logistic regression was applied between independent and dependent variables. Results: The mean score of knowledge was 7.22 ± 2.64, attitude was 4.34 ± 1.14 and practice was 4.44 ± 1.11. There was a significant difference between good and poor score for KAP. Participants with older age, good knowledge and attitude scores were more likely to have good practices. Conclusion: AWWs had good attitude and practices, but lacked adequate knowledge on IPC measures. Ensuring training for AWW on IPC is important.
{"title":"An appraisal of knowledge, attitude and practices of anganwadi workers under integrated child development services scheme on infection prevention and control in the initial months of COVID-19 pandemic in District Lucknow, UP, India","authors":"Manish Singh, M. Maurya, Ahmed Yoosuf, Shikha Nargotra, P. Pawar, Ritika Mukherjee, Archisman Mahapatro","doi":"10.4103/jme.jme_34_22","DOIUrl":"https://doi.org/10.4103/jme.jme_34_22","url":null,"abstract":"Background: During the COVID-19 pandemic, Anganwadi workers (AWWs) were repositioned for community support, community surveillance, community awareness on infection prevention and mitigating stigma/discrimination entailing infection, going door to door. The job entailed good knowledge, attitude and practices (KAP) with regard to infection prevention and control (IPC). Aims: To assess the KAP of AWW with regard to IPC in context of COVID-19 in Lucknow district. Methods: A cross-sectional survey was conducted using Google form between 30 June and 28 July 2020. AWWs were recruited from Lucknow district irrespective of their training status; data analysis was done on 137 participants. The mean KAP score was calculated and student t-test was applied. Chi-square test was performed between categorical variables and KAP. Univariate and multivariate logistic regression was applied between independent and dependent variables. Results: The mean score of knowledge was 7.22 ± 2.64, attitude was 4.34 ± 1.14 and practice was 4.44 ± 1.11. There was a significant difference between good and poor score for KAP. Participants with older age, good knowledge and attitude scores were more likely to have good practices. Conclusion: AWWs had good attitude and practices, but lacked adequate knowledge on IPC measures. Ensuring training for AWW on IPC is important.","PeriodicalId":251651,"journal":{"name":"Journal of Medical Evidence","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129307327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The coronavirus pandemic brought new challenges and opportunities for health professionals, including nurses and nursing students. Nurses worked as front-line warriors to fight against COVID-19 worldwide. They worked round the clock to deliver the best possible care to critically ill patients admitted in critical care areas and use ventilators. Therefore, many national and international agencies, including the World Health Organization (WHO), the International Council of Nurses (ICN), and the United Nations (UN) body, have acknowledged the hard work of nurses during the pandemic. This document highlights nurses' diverse roles and responsibilities during the ongoing COVID-19 pandemic. Reflection on their work will further help policymakers support nursing professionals fighting against the virus and putting themselves at inevitable risk of coronavirus.
{"title":"Highlighting the role of nurses: A reflection on COVID-19 pandemic","authors":"Raj Kumar","doi":"10.4103/jme.jme_4_22","DOIUrl":"https://doi.org/10.4103/jme.jme_4_22","url":null,"abstract":"The coronavirus pandemic brought new challenges and opportunities for health professionals, including nurses and nursing students. Nurses worked as front-line warriors to fight against COVID-19 worldwide. They worked round the clock to deliver the best possible care to critically ill patients admitted in critical care areas and use ventilators. Therefore, many national and international agencies, including the World Health Organization (WHO), the International Council of Nurses (ICN), and the United Nations (UN) body, have acknowledged the hard work of nurses during the pandemic. This document highlights nurses' diverse roles and responsibilities during the ongoing COVID-19 pandemic. Reflection on their work will further help policymakers support nursing professionals fighting against the virus and putting themselves at inevitable risk of coronavirus.","PeriodicalId":251651,"journal":{"name":"Journal of Medical Evidence","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133060442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A child with haemorrhagic bullous lesions: Atypical skin manifestation of henoch–Schonlein purpura","authors":"B. Gaur, Aafrin Bari, D. Agrawal, Divya Singh","doi":"10.4103/jme.jme_30_22","DOIUrl":"https://doi.org/10.4103/jme.jme_30_22","url":null,"abstract":"","PeriodicalId":251651,"journal":{"name":"Journal of Medical Evidence","volume":"81 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115815833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anila Varghese, A. Upadhyay, R. Daniel, Twinkle Sharma, Vivek Mohan, Balaji Susindran, Priyanka Singh, C. Lahariya
Mucormycosis emerged as a major public health challenge during the second wave of the COVID-19 pandemic in India in mid-2021. The disease, colloquially known as the Black fungus, was declared epidemic by the government. This review describes the epidemiological pattern and the determinants of mucormycosis. The review also proposes evidence based public health strategies for the prevention and control of mucormycosis. The rationale use of steroids in clinical management, formulation of evidence-based standard treatment guidelines and adherence to those guidelines by physicians, the strengthening of primary healthcare services to facilitate early care; compliance with infection prevention and control measures at all the health facilities; and early diagnosis and case management are the key strategies to prevent future emergence of mucormycosis. The article concludes that it is not enough that we tackle a health challenge at hand, in crisis mode. It is equally important that we derive learnings and take measures prevent any future. Effective control of mucormycosis and prevention of future outbreaks of disease is possible through coordinated actions of health policy makers, public health experts and clinicians. The entire episode is also a reminder for strengthening India's health systems at all levels – primary, secondary and tertiary – as well as in both public and private sector.
{"title":"Mucormycosis, COVID-19 Pandemic and the Lessons Learnt: A Review","authors":"Anila Varghese, A. Upadhyay, R. Daniel, Twinkle Sharma, Vivek Mohan, Balaji Susindran, Priyanka Singh, C. Lahariya","doi":"10.4103/jme.jme_122_22","DOIUrl":"https://doi.org/10.4103/jme.jme_122_22","url":null,"abstract":"Mucormycosis emerged as a major public health challenge during the second wave of the COVID-19 pandemic in India in mid-2021. The disease, colloquially known as the Black fungus, was declared epidemic by the government. This review describes the epidemiological pattern and the determinants of mucormycosis. The review also proposes evidence based public health strategies for the prevention and control of mucormycosis. The rationale use of steroids in clinical management, formulation of evidence-based standard treatment guidelines and adherence to those guidelines by physicians, the strengthening of primary healthcare services to facilitate early care; compliance with infection prevention and control measures at all the health facilities; and early diagnosis and case management are the key strategies to prevent future emergence of mucormycosis. The article concludes that it is not enough that we tackle a health challenge at hand, in crisis mode. It is equally important that we derive learnings and take measures prevent any future. Effective control of mucormycosis and prevention of future outbreaks of disease is possible through coordinated actions of health policy makers, public health experts and clinicians. The entire episode is also a reminder for strengthening India's health systems at all levels – primary, secondary and tertiary – as well as in both public and private sector.","PeriodicalId":251651,"journal":{"name":"Journal of Medical Evidence","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127558462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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