Pub Date : 1995-06-09DOI: 10.1109/CBMS.1995.465451
R. Gaborski, B. Jang
Proposes an image enhancement algorithm that converts raw data from a storage phosphor scanner into a diagnostically optimized image. The spatial segmentation algorithm is applied to extract the body part of a clinical image, and histogram analysis is then used to develop the tone-scale for the region of interest. Further enhancement is obtained by unsharp masking. This approach reduces the sensitivity to nonanatomical regions and allows full use of the display's dynamic range for image viewing. The algorithms have been tested on clinical images and the results were reviewed by radiologists. Currently, these algorithms are being successfully used in the clinical environment.<>
{"title":"Enhancement for computed radiographic images","authors":"R. Gaborski, B. Jang","doi":"10.1109/CBMS.1995.465451","DOIUrl":"https://doi.org/10.1109/CBMS.1995.465451","url":null,"abstract":"Proposes an image enhancement algorithm that converts raw data from a storage phosphor scanner into a diagnostically optimized image. The spatial segmentation algorithm is applied to extract the body part of a clinical image, and histogram analysis is then used to develop the tone-scale for the region of interest. Further enhancement is obtained by unsharp masking. This approach reduces the sensitivity to nonanatomical regions and allows full use of the display's dynamic range for image viewing. The algorithms have been tested on clinical images and the results were reviewed by radiologists. Currently, these algorithms are being successfully used in the clinical environment.<<ETX>>","PeriodicalId":254366,"journal":{"name":"Proceedings Eighth IEEE Symposium on Computer-Based Medical Systems","volume":"298 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1995-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114010850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1995-06-09DOI: 10.1109/CBMS.1995.465443
M. Davis, A. Khotanzad, D. Flamig, S. Harms
In a landmark based medical image matching scheme, a coordinate transformation maps a set of landmark locations in one image onto a corresponding set in a second image. A novel approach to this transformation, the elastic body spline, is introduced. The development of the spline is outlined. An example of using the spline to match 3D magnetic resonance images (MRIs) of the breast is described. The elastic body spline is compared to the thin plate spline and, for 3D breast MRIs, is found to have superior performance as assessed by several measures of the similarity of the matched images.<>
{"title":"Elastic body splines: a physics based approach to coordinate transformation in medical image matching","authors":"M. Davis, A. Khotanzad, D. Flamig, S. Harms","doi":"10.1109/CBMS.1995.465443","DOIUrl":"https://doi.org/10.1109/CBMS.1995.465443","url":null,"abstract":"In a landmark based medical image matching scheme, a coordinate transformation maps a set of landmark locations in one image onto a corresponding set in a second image. A novel approach to this transformation, the elastic body spline, is introduced. The development of the spline is outlined. An example of using the spline to match 3D magnetic resonance images (MRIs) of the breast is described. The elastic body spline is compared to the thin plate spline and, for 3D breast MRIs, is found to have superior performance as assessed by several measures of the similarity of the matched images.<<ETX>>","PeriodicalId":254366,"journal":{"name":"Proceedings Eighth IEEE Symposium on Computer-Based Medical Systems","volume":"306 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1995-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131650875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1995-06-09DOI: 10.1109/CBMS.1995.465422
J. Xia, Feihu Qi, W. Yuan, Dongfeng Wang, W. Qiu, Yi Sun, Yuanliang Huang, Guofang Shen, Hai-ting Wu
The easy simulation of orthognathic surgery with high accuracy and good reliability, and the visual explanation of the prediction of surgery to patients with marillo-mandibular deformities remains a key focus in oral and maxillofacial surgery. A Computer-Aided Simulation System for Orthognathic Surgery (CASSOS) was developed by means of the technique of digital image processing, with which a detailed analysis could be performed automatically, including 71 measurements of distance, degree and ratio for frontal cephalograms and 68 measurements for lateral ones, with computer-aided diagnosis. A quantitative surgical simulation for the prediction of operations could be satisfactorily carried out for clinical use. All data and images were printed by Laserjet and color videoprinters. All procedures were finished in 20 minutes.<>
{"title":"Computer Aided Simulation System for Orthognathic Surgery","authors":"J. Xia, Feihu Qi, W. Yuan, Dongfeng Wang, W. Qiu, Yi Sun, Yuanliang Huang, Guofang Shen, Hai-ting Wu","doi":"10.1109/CBMS.1995.465422","DOIUrl":"https://doi.org/10.1109/CBMS.1995.465422","url":null,"abstract":"The easy simulation of orthognathic surgery with high accuracy and good reliability, and the visual explanation of the prediction of surgery to patients with marillo-mandibular deformities remains a key focus in oral and maxillofacial surgery. A Computer-Aided Simulation System for Orthognathic Surgery (CASSOS) was developed by means of the technique of digital image processing, with which a detailed analysis could be performed automatically, including 71 measurements of distance, degree and ratio for frontal cephalograms and 68 measurements for lateral ones, with computer-aided diagnosis. A quantitative surgical simulation for the prediction of operations could be satisfactorily carried out for clinical use. All data and images were printed by Laserjet and color videoprinters. All procedures were finished in 20 minutes.<<ETX>>","PeriodicalId":254366,"journal":{"name":"Proceedings Eighth IEEE Symposium on Computer-Based Medical Systems","volume":"103 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1995-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131946538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1995-06-09DOI: 10.1109/CBMS.1995.465410
J. Auñón, T. Aljama-Corrales
Traditionally, researchers have studied each sensory modality and its effect on human perception as a discrete process. However, every-day perceptual experiences integrate a variety of sensory inputs. Examining each sensory path independently can lead to a partial understanding of their total capabilities and their impact on the cognitive function. Normally, two or more modalities can carry information about the same event or different sensory modalities can be simultaneously stimulated by different events. The effects on interstimulus interval on the bisensory evoked potential are reported for cases when the auditory and visual stimulus are separated by as much as 100 ms.<>
{"title":"Evoked potentials and intersensory information processing","authors":"J. Auñón, T. Aljama-Corrales","doi":"10.1109/CBMS.1995.465410","DOIUrl":"https://doi.org/10.1109/CBMS.1995.465410","url":null,"abstract":"Traditionally, researchers have studied each sensory modality and its effect on human perception as a discrete process. However, every-day perceptual experiences integrate a variety of sensory inputs. Examining each sensory path independently can lead to a partial understanding of their total capabilities and their impact on the cognitive function. Normally, two or more modalities can carry information about the same event or different sensory modalities can be simultaneously stimulated by different events. The effects on interstimulus interval on the bisensory evoked potential are reported for cases when the auditory and visual stimulus are separated by as much as 100 ms.<<ETX>>","PeriodicalId":254366,"journal":{"name":"Proceedings Eighth IEEE Symposium on Computer-Based Medical Systems","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1995-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133738184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1995-06-09DOI: 10.1109/CBMS.1995.465444
Young-Sik Choi, R. Krishnapuram
Using fuzzy set theory, we develop a fuzzy rule-based system to perform some of the most common tasks of image enhancement: removing impulsive noise; smoothing nonimpulsive noise; and enhancing edges. Three different filters for each task and the selection criteria based on local information are derived. The selection criteria constitute the antecedent clauses of the fuzzy rules, and the corresponding filters constitute the consequent clauses of the fuzzy rules. The overall result of the fuzzy rule-based system is computed as the combination of the results of the individual filters, where each result contributes to the degree that the corresponding antecedent clause is satisfied. This approach gives us a powerful and flexible image enhancement paradigm. We present results on several types of images such as retinal and chromosome images.<>
{"title":"A fuzzy-rule-based image enhancement method for medical applications","authors":"Young-Sik Choi, R. Krishnapuram","doi":"10.1109/CBMS.1995.465444","DOIUrl":"https://doi.org/10.1109/CBMS.1995.465444","url":null,"abstract":"Using fuzzy set theory, we develop a fuzzy rule-based system to perform some of the most common tasks of image enhancement: removing impulsive noise; smoothing nonimpulsive noise; and enhancing edges. Three different filters for each task and the selection criteria based on local information are derived. The selection criteria constitute the antecedent clauses of the fuzzy rules, and the corresponding filters constitute the consequent clauses of the fuzzy rules. The overall result of the fuzzy rule-based system is computed as the combination of the results of the individual filters, where each result contributes to the degree that the corresponding antecedent clause is satisfied. This approach gives us a powerful and flexible image enhancement paradigm. We present results on several types of images such as retinal and chromosome images.<<ETX>>","PeriodicalId":254366,"journal":{"name":"Proceedings Eighth IEEE Symposium on Computer-Based Medical Systems","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1995-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133027521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1995-06-09DOI: 10.1109/CBMS.1995.465428
R. Muyshondt, S. Mitra
The past few years have seen a rapid development in the areas of image compression techniques. This increase is mainly attributed to the current need for efficient storage and fast transmission of data among individuals using the information superhighway. A particular place of interest is in the area of telemedicine, where rapid transmission and effective storage leads to price reduction in medical costs. Thus, in order to achieve maximal storage and transmission parameters, the different compression algorithms should be compared in order to find an optimal technique for medical image compression. In this paper, we compare the performance of the wavelet transform to the current JPEG standard. We performed our comparisons on radiographic images and used criteria such as visual quality, peak signal-to-noise ratio and mean square error, in order to judge the compression capabilities of both techniques. Wavelet reconstructed images outperformed JPEG reconstruction in all the above criteria.<>
{"title":"Visual fidelity of reconstructed radiographic images using wavelet transform coding and JPEG","authors":"R. Muyshondt, S. Mitra","doi":"10.1109/CBMS.1995.465428","DOIUrl":"https://doi.org/10.1109/CBMS.1995.465428","url":null,"abstract":"The past few years have seen a rapid development in the areas of image compression techniques. This increase is mainly attributed to the current need for efficient storage and fast transmission of data among individuals using the information superhighway. A particular place of interest is in the area of telemedicine, where rapid transmission and effective storage leads to price reduction in medical costs. Thus, in order to achieve maximal storage and transmission parameters, the different compression algorithms should be compared in order to find an optimal technique for medical image compression. In this paper, we compare the performance of the wavelet transform to the current JPEG standard. We performed our comparisons on radiographic images and used criteria such as visual quality, peak signal-to-noise ratio and mean square error, in order to judge the compression capabilities of both techniques. Wavelet reconstructed images outperformed JPEG reconstruction in all the above criteria.<<ETX>>","PeriodicalId":254366,"journal":{"name":"Proceedings Eighth IEEE Symposium on Computer-Based Medical Systems","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1995-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117277858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1995-06-09DOI: 10.1109/CBMS.1995.465421
D. Bornhop, M. Houlne
Recent advances in optics and CCD imaging technology have made possible the advent of small, position sensitive, articulating endoscopes allowing visual access to small cavities within the human body. We present our results for the design, construction and evaluation of a spectrometer capable of measuring molecular fluorescence phenomena as a function of wavelength, position and intensity in small cavities. State-of-the-art micro-endoscope technology is combined with wavelength sorting and CCD imaging to accomplish remote imaging. Presently, images can be magnified by 50x with visual resolution of about 50 LP/mm by direct observation of a USAF resolution target. We detail our biological cell imaging results where a special class of fluorescent molecules (chelate complexes of lathinide (III) polyazamacrocyclic acetates containing pyridine) are introduced into osteosarcoma tissue (a bone cancer tissue). It is shown that the unique molecular site selectivity of the Tb-+3 compound combined with the microendoscopic spectrometer is a useful tool for osteosarcoma rat host investigations in-vivo. We demonstrate that direct observation of the probe molecules in the tissue can yield physiological information regarding interstitial fluid flow in the osteosarcoma tumors.<>
{"title":"Spectroscopic imaging of tissues using micro-endoscopy","authors":"D. Bornhop, M. Houlne","doi":"10.1109/CBMS.1995.465421","DOIUrl":"https://doi.org/10.1109/CBMS.1995.465421","url":null,"abstract":"Recent advances in optics and CCD imaging technology have made possible the advent of small, position sensitive, articulating endoscopes allowing visual access to small cavities within the human body. We present our results for the design, construction and evaluation of a spectrometer capable of measuring molecular fluorescence phenomena as a function of wavelength, position and intensity in small cavities. State-of-the-art micro-endoscope technology is combined with wavelength sorting and CCD imaging to accomplish remote imaging. Presently, images can be magnified by 50x with visual resolution of about 50 LP/mm by direct observation of a USAF resolution target. We detail our biological cell imaging results where a special class of fluorescent molecules (chelate complexes of lathinide (III) polyazamacrocyclic acetates containing pyridine) are introduced into osteosarcoma tissue (a bone cancer tissue). It is shown that the unique molecular site selectivity of the Tb-+3 compound combined with the microendoscopic spectrometer is a useful tool for osteosarcoma rat host investigations in-vivo. We demonstrate that direct observation of the probe molecules in the tissue can yield physiological information regarding interstitial fluid flow in the osteosarcoma tumors.<<ETX>>","PeriodicalId":254366,"journal":{"name":"Proceedings Eighth IEEE Symposium on Computer-Based Medical Systems","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1995-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116506963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1995-06-09DOI: 10.1109/CBMS.1995.465455
A. Sarvazyan, A. R. Skovoroda, Y. Pyt’ev
Summary form only given. Mechanical introscopy is based on the reconstruction of the internal structure of soft body tissues by measuring the surface distribution of stress/strain patterns using a pressure sensor array. This new technology of medical imaging does not use any form of potentially hazardous radiation. It provides information on the internal structure of the organ and enables physicians to obtain values of the elasticity modulus of internal lesions and to characterize their hardness, which is indicative of cancer development. This paper presents the results of mathematical simulation and model experiments on visualizing the structure and evaluating the properties of internal tissues from a pattern of mechanical stresses developed by an array of pressure sensors that is pressed statically or dynamically against investigated tissues or a body part. The resulting pattern of mechanical stress and its changes as a function of applied pressure and time contain comprehensive information on the mechanical properties and geometry of the internal structures which can be calculated from the pattern by solving the inverse problem. Mechanical introscopy meets all the requirements for a mass cancer screening method: it is simple, fast, inexpensive and safe.<>
{"title":"Mechanical introscopy-a new modality of medical imaging for detection of breast and prostate cancer","authors":"A. Sarvazyan, A. R. Skovoroda, Y. Pyt’ev","doi":"10.1109/CBMS.1995.465455","DOIUrl":"https://doi.org/10.1109/CBMS.1995.465455","url":null,"abstract":"Summary form only given. Mechanical introscopy is based on the reconstruction of the internal structure of soft body tissues by measuring the surface distribution of stress/strain patterns using a pressure sensor array. This new technology of medical imaging does not use any form of potentially hazardous radiation. It provides information on the internal structure of the organ and enables physicians to obtain values of the elasticity modulus of internal lesions and to characterize their hardness, which is indicative of cancer development. This paper presents the results of mathematical simulation and model experiments on visualizing the structure and evaluating the properties of internal tissues from a pattern of mechanical stresses developed by an array of pressure sensors that is pressed statically or dynamically against investigated tissues or a body part. The resulting pattern of mechanical stress and its changes as a function of applied pressure and time contain comprehensive information on the mechanical properties and geometry of the internal structures which can be calculated from the pattern by solving the inverse problem. Mechanical introscopy meets all the requirements for a mass cancer screening method: it is simple, fast, inexpensive and safe.<<ETX>>","PeriodicalId":254366,"journal":{"name":"Proceedings Eighth IEEE Symposium on Computer-Based Medical Systems","volume":"376 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1995-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131167698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1995-06-09DOI: 10.1109/CBMS.1995.465414
L. Long, Lewis E. Berman, G. Thoma
At the National Library of Medicine (NLM), an application-level technique for improving the transmission rate of large images across the Internet has been developed. Initial performance tests were conducted in 1994 and evaluation has continued with a series of tests conducted with cervical X-ray image files transmitted from Texas Tech University, the University of Arizona and the NASA Lewis Research Center to NLM. Statistics were collected to compare the observed transmission rate using the NLM technique versus conventional FTP transmission. On the links tested, the average transmission rate using the new technique showed a consistent improvement over conventional methods, including a 2- to 3-fold improvement on the Tucson and Cleveland tests. Work is now underway to extend the initial implementation into a portable, robust technique. In this paper, we present high-level design concepts for the second implementation and provide results of the most recent tests.<>
{"title":"Client/server design for fast retrieval of large images on the Internet","authors":"L. Long, Lewis E. Berman, G. Thoma","doi":"10.1109/CBMS.1995.465414","DOIUrl":"https://doi.org/10.1109/CBMS.1995.465414","url":null,"abstract":"At the National Library of Medicine (NLM), an application-level technique for improving the transmission rate of large images across the Internet has been developed. Initial performance tests were conducted in 1994 and evaluation has continued with a series of tests conducted with cervical X-ray image files transmitted from Texas Tech University, the University of Arizona and the NASA Lewis Research Center to NLM. Statistics were collected to compare the observed transmission rate using the NLM technique versus conventional FTP transmission. On the links tested, the average transmission rate using the new technique showed a consistent improvement over conventional methods, including a 2- to 3-fold improvement on the Tucson and Cleveland tests. Work is now underway to extend the initial implementation into a portable, robust technique. In this paper, we present high-level design concepts for the second implementation and provide results of the most recent tests.<<ETX>>","PeriodicalId":254366,"journal":{"name":"Proceedings Eighth IEEE Symposium on Computer-Based Medical Systems","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1995-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127526159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1995-06-09DOI: 10.1109/CBMS.1995.465409
J. Ramírez-Cortés, Guillermo Bolanos, José Miguel David Báez-López
Presents a simple and low-cost PC-based system to convert and ASCII file into oral language (Spanish) as a vision impaired aid. Three major parts can be distinguished: a database with a set of the most used syllables, which was constructed after research on the Spanish language, an extension board connected to the expansion slot of the PC, and the software required to perform the manipulation of the signals in both parts, speech acquisition and synthesis. The system is currently under testing with good results. General performance and conclusions are discussed.<>
{"title":"A low-cost speech-synthesis system for translation of ASCII text to oral language as a vision impaired aid","authors":"J. Ramírez-Cortés, Guillermo Bolanos, José Miguel David Báez-López","doi":"10.1109/CBMS.1995.465409","DOIUrl":"https://doi.org/10.1109/CBMS.1995.465409","url":null,"abstract":"Presents a simple and low-cost PC-based system to convert and ASCII file into oral language (Spanish) as a vision impaired aid. Three major parts can be distinguished: a database with a set of the most used syllables, which was constructed after research on the Spanish language, an extension board connected to the expansion slot of the PC, and the software required to perform the manipulation of the signals in both parts, speech acquisition and synthesis. The system is currently under testing with good results. General performance and conclusions are discussed.<<ETX>>","PeriodicalId":254366,"journal":{"name":"Proceedings Eighth IEEE Symposium on Computer-Based Medical Systems","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1995-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114884514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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