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Quantitative methods in medical imaging 医学影像学中的定量方法
Pub Date : 1995-06-09 DOI: 10.1109/CBMS.1995.465419
M. Loew
Measurement and comparison of medical images is of growing importance for several reasons: (1) as medical imaging becomes ever more digital, and networks and archives of images proliferate, the opportunity will create the need; (2) automated approaches to treatment design, dose measurement, and surgery planning are emerging from the laboratory and entering limited clinical use; and (3) a greater variety of users wants to employ the reliable and repeatable methodology that seems to be offered by the automated methods. Image-processing tools give us some characterization of shape, size, texture, color, depth and three-dimensionality. Combined with properties of the imaging modality and knowledge of anatomy, they yield quantitative descriptions that are useful in differential diagnosis. What has received little attention, however, is the need for benchmarking and evaluation of the various methods available. Almost nothing has been done to ensure the comparability of reported results. The user interface, which may be the clinician's only contact with the application system, has not claimed appreciably more study by system designers than benchmarking. As the need grows to justify the expense of imaging, analysis of its benefits will have to be measured, but until good criteria exist for assessing the imaging system, there cannot be a reliable way to measure outcomes. Equally, use of images from other sites for teaching and research will be impeded in the absence of such metrics. This paper outlines the problem and suggests some steps that can be taken to bring real quantification to medical imaging.<>
由于以下几个原因,医学图像的测量和比较变得越来越重要:(1)随着医学成像变得越来越数字化,图像网络和档案的激增,机会将创造需求;(2)治疗设计、剂量测量和手术计划的自动化方法正在从实验室出现,并进入有限的临床应用;(3)越来越多的用户希望采用自动化方法提供的可靠和可重复的方法。图像处理工具给我们一些形状、大小、纹理、颜色、深度和三维特征。结合成像方式的特性和解剖学知识,它们产生了对鉴别诊断有用的定量描述。然而,很少受到注意的是需要对现有的各种方法进行基准和评价。几乎没有采取任何措施来确保报告结果的可比性。用户界面,这可能是临床医生与应用系统的唯一接触,并没有要求系统设计者比基准测试更多的研究。随着需要证明成像费用的增长,必须对其效益进行分析,但在评估成像系统的良好标准存在之前,不可能有可靠的方法来衡量结果。同样,如果没有这样的标准,使用其他网站的图像进行教学和研究也会受到阻碍。本文概述了这个问题,并提出了一些可以采取的措施,使医学成像真正量化。
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引用次数: 0
Application of multi-dimensional quality measures to reconstructed medical images 多维质量测度在医学图像重建中的应用
Pub Date : 1995-06-09 DOI: 10.1109/CBMS.1995.465454
A. Eskicioglu
Lossy compression drastically reduces the operating costs of digital medical imaging systems by allowing more efficient use of transmission and archival facilities in hospitals and doctors' offices. To be able to develop standards for the application of this technology, reliable tools are needed for measuring the quality of reconstructed images. Among the most common measures presently used, the normalized mean squared error (NMSE) does not provide any information concerning the type of impairment, and receiver operating characteristic (ROC) analyses are expensive and time-consuming. This paper evaluates the performance of three quantitative multi-dimensional measures for image quality. Mimicking the human visual system, they compute local features, and produce a graphical output. Eskicioglu charts, in particular, are shown to be an appropriate tool for characterizing compression losses in reconstructed medical images.<>
有损压缩允许更有效地利用医院和医生办公室的传输和存档设施,从而大大降低了数字医学成像系统的运营成本。为了能够为这项技术的应用制定标准,需要可靠的工具来测量重建图像的质量。在目前使用的最常用的测量方法中,归一化均方误差(NMSE)不能提供有关损伤类型的任何信息,而受试者工作特征(ROC)分析既昂贵又耗时。本文对图像质量的三种定量多维度量的性能进行了评价。它们模仿人类的视觉系统,计算局部特征,并产生图形输出。特别是,Eskicioglu图表被证明是表征重建医学图像中压缩损失的适当工具。
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引用次数: 19
Adaptive environmental control for optimal energy consumption in hospitals 医院能耗优化的自适应环境控制
Pub Date : 1995-06-09 DOI: 10.1109/CBMS.1995.465434
E. Kaymaz
A second order dynamical model of the heating/cooling process in a hospital building is simulated. A fuzzy logic controller (FLC) based on if-then control rules is designed and the performance of the FLC is compared with that of commonly used on/off and PI/PID controllers. Both the FLC and the PI/PID controllers outperform the on/off controller in terms of accuracy, as well as energy consumption. However, the FLC is more robust than the PI/PID controllers in that the FLC is much less sensitive to changes in system parameters and consumes less energy.<>
建立了医院建筑冷热过程的二阶动力学模型。设计了一种基于if-then控制规则的模糊控制器(FLC),并将其性能与常用的on/off控制器和PI/PID控制器进行了比较。FLC和PI/PID控制器在精度和能耗方面都优于开/关控制器。然而,FLC比PI/PID控制器更鲁棒,因为FLC对系统参数变化的敏感性要低得多,并且消耗的能量更少。
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引用次数: 6
Manipulation of volume and graphics objects for the visualization of medical data under OpenGL 在OpenGL下操作用于医疗数据可视化的体积和图形对象
Pub Date : 1995-06-09 DOI: 10.1109/CBMS.1995.465442
Z. Lee, P. Diaz, E. Bellon
Combined rendering of volume data and geometric objects (graphics objects) is important in a number of medical applications. Efficient generation of such rendering is required to support user interactions at a level that are useful in clinical applications. In this study, we describe the manipulation of graphics objects with volume data utilizing a widely used graphics API standard, OpenGL.<>
体数据和几何对象(图形对象)的组合呈现在许多医疗应用中很重要。为了支持在临床应用中有用的用户交互,需要有效地生成这种渲染。在这项研究中,我们描述了使用广泛使用的图形API标准OpenGL对图形对象的操作。
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引用次数: 3
Design by documentation: a method and case study 文档设计:一种方法和案例研究
Pub Date : 1995-06-09 DOI: 10.1109/CBMS.1995.465416
M. Manwaring, V. Malbasa, K. Manwaring
We present a "design by documentation" approach to the design of dedicated computer systems. The method is natural, easy to apply, and results with the documentation that is simultaneously developed with the project design steps. The approach allows the designer and the customer to validate the design goals throughout the design process by assessing the documentation on the midterm checkpoints of the project. The approach is illustrated through a case study of the design of intracranial pressure monitor for medical application.<>
我们提出了一种“通过文档设计”的方法来设计专用计算机系统。该方法很自然,易于应用,并且与项目设计步骤同时开发的文档一起产生。该方法允许设计师和客户通过评估项目中期检查点的文档,在整个设计过程中验证设计目标。最后以医疗用颅内压监测仪的设计为例,对该方法进行了说明
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引用次数: 0
A self-organizing neural net clustering Parkinson patients and control persons using motor data 基于运动数据的自组织神经网络聚类帕金森患者和对照组
Pub Date : 1995-06-09 DOI: 10.1109/CBMS.1995.465439
T. Fritsch, B. Neuner, P. Klotz, P. Kraus
Parkinson's disease (PD) is a neurodegenerative disorder characterized by akinesia (absence or poverty of voluntary movements), rigidity (increased muscular tonus) and tremor (involuntary oscillation). Control of the course of disease and therapeutic measures impose great demands on standardisation of clinical evaluation, including standards of therapeutic control and means of disease monitoring as well as for proof of efficacy of new therapeutic substances. We present the results of the application of a self-organizing feature map (SOM) to training data, obtained from a large study, where more than 450 patients have been observed under therapy for over 2 years. The training data are obtained from an instrumental test battery, whose items like steadiness, aiming or tapping describe the motor impairment of the patients for given tasks. Different SOM nets with a size of 50/spl times/50 neurons were presented to learn 501 data sets including 49 control persons, each set consisting of 28 components. The result of the learning process, which has been achieved after 10,000 learning steps is the clear separation of Parkinsonian patients from the control persons by the neural net.<>
帕金森病(PD)是一种神经退行性疾病,其特征是运动障碍(缺乏或缺乏自主运动)、僵硬(肌肉张力增加)和震颤(不自主振荡)。对疾病进程和治疗措施的控制,对临床评价的规范化提出了很高的要求,包括治疗控制标准和疾病监测手段标准,以及新的治疗物质的疗效证明标准。我们展示了将自组织特征图(SOM)应用于训练数据的结果,该结果来自一项大型研究,该研究观察了450多名接受治疗超过2年的患者。训练数据来自一个仪器测试电池,它的稳定性、瞄准或敲击等项目描述了患者在完成特定任务时的运动障碍。采用50/spl次/50个神经元大小的不同SOM网络学习501个数据集,其中49个为对照,每个数据集由28个组成。经过一万步的学习,学习过程的结果是神经网络将帕金森病患者与对照组明确区分开来。
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引用次数: 4
Automated rapid seizure detection in the human ECoG 人类脑电图的自动快速癫痫检测
Pub Date : 1995-06-09 DOI: 10.1109/CBMS.1995.465407
I. Osorio, M. Frei, D. Lerner, S. Wilkinson
Summary form only given. Automated seizure detection with high specificity and sensitivity is a highly desirable but elusive goal. The failure to develop a reliable system despite decades of effort is due in part to the non-stationary and noise in the EEG/ECoG signals, as well as to the rudimentary mathematical treatment it has received. We have developed a method of automated seizure detection based on a combination of linear and nonlinear filtering techniques, including the discrete wavelet transform. To minimize noise, this method was first developed for intracranial signals, then later adapted to scalp recordings. Preliminary results indicate that this new method may be the fastest and most reliable to date. The generic algorithm has been tested on 5 patients and a total of 20 seizure segments and 7 interictal segments recorded form intracranial electrodes. We have also compared the method to expert visual analysis, performed through a review of polygraph tracings of the signals, and have found our method to be both fast and highly accurate. We are generally able to detect the electrographic seizure within a second of the time marked by the EEGer. The method is also highly adaptable-it automatically accounts for signal changes over time, and has a number of parameters which may be tuned to further improve accuracy for a given individual patient or for a particular signal or group of signals being monitored. The algorithm has been implemented and now allows real-time monitoring and detection on a 486/DX 33 MHz PC.<>
只提供摘要形式。具有高特异性和敏感性的自动癫痫检测是一个非常理想但难以实现的目标。尽管经过数十年的努力,仍未能开发出可靠的系统,部分原因是EEG/ECoG信号中的非平稳和噪声,以及它所接受的基本数学处理。我们开发了一种基于线性和非线性滤波技术的自动检测方法,包括离散小波变换。为了最大限度地减少噪声,这种方法首先用于颅内信号,然后适用于头皮记录。初步结果表明,这种新方法可能是迄今为止最快和最可靠的。该通用算法已在5例患者身上进行了测试,共记录了颅内电极记录的20个发作段和7个间歇段。我们还将该方法与专家视觉分析进行了比较,通过对信号的测谎仪跟踪进行审查,发现我们的方法既快速又高度准确。我们通常能够在EEGer标记的一秒钟内检测到电图癫痫发作。该方法还具有高度的适应性——它可以自动考虑信号随时间的变化,并且具有许多参数,这些参数可以调整以进一步提高给定个体患者或特定信号或被监测信号组的准确性。该算法已经实现,现在可以在486/DX 33 MHz PC上进行实时监控和检测。
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引用次数: 2
Comparison of complexity of laporoscopy and laporotomy operations by estimation of patient's stress using a noninvasive computerized method 用非侵入性计算机方法估计病人压力,比较腹腔镜和剖腹手术的复杂性
Pub Date : 1995-06-09 DOI: 10.1109/CBMS.1995.465424
T. Slonim, M. Slonim, G. Daychamn, I. Ovsyshcher, L. Roytblat
A new approach is proposed for the estimation of heart rate variability (HRV) under surgical stress conditions. An HRV index (HRVI) has been introduced. The complexity of laporoscopy (LS) and laporotomy (LT) surgical operations has been evaluated.<>
提出了一种在手术应激条件下估计心率变异性(HRV)的新方法。引入了HRV指数(HRVI)。腹腔镜(LS)和剖腹手术(LT)手术的复杂性已被评估。
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引用次数: 0
Primary interpretation of medical imagery by teleradiology 远程放射学对医学图像的初步解释
Pub Date : 1995-06-09 DOI: 10.1109/CBMS.1995.465417
G. H. Roberson, Y. Shieh
For a majority of applications, teleradiology has been regarded primarily as a convenience for the on-call radiologist by transmitting radiographic images to the his/her residence so that an after-hour trip to the hospital can be avoided. Under such a operation environment, the images acquired and transmitted are not designed to meet the requirements of primary interpretation. The image quality required is relatively low order since the original films will be reviewed and dictated the following day. Currently teleradiology is being seriously considered as the means for doing primary diagnosis. In other words, a final diagnosis report will be generated by interpreting the soft copy of the image displayed on the monitor without any reference to the original film. Such a paradigm shift raised many technical as well as clinical issues that must be addressed. The radiology department of Texas Tech University Health Sciences Center began efforts in teleradiology since March 1994. A number of key issues and experiences learned from our practising teleradiology in the past several months are presented in this paper.<>
在大多数应用中,远程放射学主要被认为是为随叫随到的放射科医生提供方便,通过将放射图像传送到他/她的住所,从而避免了一小时后去医院的路程。在这样的操作环境下,采集和传输的图像并不能满足初级解译的要求。由于原始电影将在第二天进行审查和口述,因此对图像质量的要求相对较低。目前,远程放射学正在被认真考虑作为进行初步诊断的手段。换句话说,在不参考原始胶片的情况下,通过解读显示器上显示的图像的软拷贝生成最终诊断报告。这种模式的转变提出了许多必须解决的技术和临床问题。德克萨斯理工大学健康科学中心放射学系自1994年3月开始在远程放射学方面开展工作。本文介绍了我们在过去几个月从事放射医学工作中所遇到的一些关键问题和经验。
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引用次数: 0
Problems of optimization with application to prosthetic design and stress fracture prediction 优化及其在假肢设计和应力断裂预测中的应用问题
Pub Date : 1995-06-09 DOI: 10.1109/CBMS.1995.465415
C. Martin, Carroll Nunn, Carroll Schovanec
Examines the effects of geometry and material properties on criteria that could be used in establishing a notion of optimal form in bone or prosthetic devices. This is accomplished by determining extreme values of functionals that are measures of strain energy and compliance. The governing differential equation includes the effects of collageneous tissue acting on the bone and in the case of the prosthetic model, interfacial interactions between the device and the bone. Augmented Lagrange techniques and non-linear conjugate gradient methods are used to determine the optimal solution.<>
检查几何形状和材料特性对标准的影响,这些标准可用于在骨骼或假体装置中建立最佳形式的概念。这是通过确定函数的极值来实现的,函数是应变能和顺应性的度量。控制微分方程包括作用于骨骼的胶原组织的影响,以及在假肢模型的情况下,设备和骨骼之间的界面相互作用。利用增广拉格朗日技术和非线性共轭梯度法确定了最优解。
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引用次数: 0
期刊
Proceedings Eighth IEEE Symposium on Computer-Based Medical Systems
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