Fidel Rodríguez-López, Hugo A. García-Gutiérrez, Rocío Gámez-Montaño
net/event/ecsoc-26. Abstract: Herein we describe the synthesis of a series of four novel triterpenoid-derived bis -amides, employing masticadienonic acid from Pistacia mexicana as a carboxylic acid component in the Ugi reaction. Products were obtained via a facile and efficient one-pot procedure under mild green conditions, with moderate yields (29–58%). The stereo-electronic nature of the aldehyde component influenced the reaction yields.
{"title":"Synthesis of Bis-Amides Employing a Plant-Derived Triterpenoid as Component in the Ugi Reaction","authors":"Fidel Rodríguez-López, Hugo A. García-Gutiérrez, Rocío Gámez-Montaño","doi":"10.3390/ecsoc-26-13560","DOIUrl":"https://doi.org/10.3390/ecsoc-26-13560","url":null,"abstract":"net/event/ecsoc-26. Abstract: Herein we describe the synthesis of a series of four novel triterpenoid-derived bis -amides, employing masticadienonic acid from Pistacia mexicana as a carboxylic acid component in the Ugi reaction. Products were obtained via a facile and efficient one-pot procedure under mild green conditions, with moderate yields (29–58%). The stereo-electronic nature of the aldehyde component influenced the reaction yields.","PeriodicalId":255032,"journal":{"name":"The 26th International Electronic Conference on Synthetic Organic Chemistry","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121466642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. K. Makarova, L. Dzhemileva, A. Makarov, U. Dzhemilev
{"title":"Synthesis of 1,3-Diyne Derivatives of Lembehyne B with Antitumor and Neuritogenic Activity","authors":"E. K. Makarova, L. Dzhemileva, A. Makarov, U. Dzhemilev","doi":"10.3390/ecsoc-26-13525","DOIUrl":"https://doi.org/10.3390/ecsoc-26-13525","url":null,"abstract":"","PeriodicalId":255032,"journal":{"name":"The 26th International Electronic Conference on Synthetic Organic Chemistry","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131181144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Vázquez-Tato, F. Meijide, F. Fraga, J. V. Tato, J. Seijas
aromatic hydrocarbons are versatile building blocks for conjugated materials and can be applied in molecular electronics. Pyrenes are known as the best organic chromophores, and pyrene itself is known as an electron donor. Likewise, quinones are promising electrode materials for lithium-ion batteries. The calculations were performed for pyrene-4,5,9,10-tetrathione, pyrene-4,5,9,10-tetraselenone and pyrene-4,5,9,10-tetratellurone, and the results were compared with those for pyrene-4,5,9,10-tetraone. The results obtained indicate that the sulfur derivative is a suitable candidate for further experimental studies since, although selenium and tellurium compounds present better prospects than 4,5,9,10-tetraoxopyrene, they require the improvement of available synthetic techniques or even the discovery of new ones.
{"title":"Pyrene-4,5,9,10-Tetrachalcogenone Derivatives: A Computational Study on Their Potential Use as Materials for Batteries","authors":"M. Vázquez-Tato, F. Meijide, F. Fraga, J. V. Tato, J. Seijas","doi":"10.3390/ecsoc-26-13554","DOIUrl":"https://doi.org/10.3390/ecsoc-26-13554","url":null,"abstract":"aromatic hydrocarbons are versatile building blocks for conjugated materials and can be applied in molecular electronics. Pyrenes are known as the best organic chromophores, and pyrene itself is known as an electron donor. Likewise, quinones are promising electrode materials for lithium-ion batteries. The calculations were performed for pyrene-4,5,9,10-tetrathione, pyrene-4,5,9,10-tetraselenone and pyrene-4,5,9,10-tetratellurone, and the results were compared with those for pyrene-4,5,9,10-tetraone. The results obtained indicate that the sulfur derivative is a suitable candidate for further experimental studies since, although selenium and tellurium compounds present better prospects than 4,5,9,10-tetraoxopyrene, they require the improvement of available synthetic techniques or even the discovery of new ones.","PeriodicalId":255032,"journal":{"name":"The 26th International Electronic Conference on Synthetic Organic Chemistry","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127787226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elizaveta R. Lominoga, P. Zadorozhnii, V. Kiselev, A. V. Kharchenko
: Derivatives of 1,3,5-oxadiazine are of interest to pharmacy, medicine, and agriculture as potential biologically active substances. These compounds have found wide application in organic synthesis and supramolecular chemistry. In this paper, we discuss and compare the effectiveness of two approaches to the dehydrosulfurization of 4-chloro-N -(2,2,2-trichloro-1-(3-arylthioureido)ethyl) benzamides resulting in the formation of 6-(4-chlorophenyl)- N -aryl-4-(trichloromethyl)-4 H -1,3,5-oxadiazin-2-amines. Dicyclohexylcarbodiimide (DCC) or a mixture of iodine with triethylamine was used as a dehydrosulfurizing agent. It is shown that, in the case of using DCC, the target products are predominantly formed in high yields. However, the use of the I 2 + Et 3 N mixture made it possible to obtain several new compounds of this class, which could not be obtained under the DCC action. The structure of all new compounds was confirmed by 1 H and 13 C NMR spectroscopy data.
1,3,5-恶二嗪的衍生物作为潜在的生物活性物质在药学、医学和农业领域具有广泛的应用价值。这些化合物在有机合成和超分子化学中有着广泛的应用。本文讨论并比较了4-氯-N -(2,2,2-三氯-1-(3-芳基硫脲基)乙基)苯酰胺脱氢硫化的两种方法的有效性，从而生成6-(4-氯苯基)- N -芳基-4-(三氯甲基)-4 H -1,3,5-恶二嗪-2胺。用二环己基碳二亚胺(DCC)或碘与三乙胺的混合物作为脱氢硫化剂。结果表明，在使用DCC的情况下，目标产品主要以高产量形成。然而，使用i2 + Et 3n的混合物可以得到一些在DCC作用下无法得到的该类新化合物。所有新化合物的结构都通过1h和13c核磁共振谱数据得到证实。
{"title":"Synthesis of 6-(4-Chlorophenyl)-N-aryl-4-(trichloromethyl)-4H-1,3,5-oxadiazin-2-amines: A Comparative Evaluation of Dehydrosulfurization Methods of Starting 4-Chloro-N-(2,2,2 -trichloro-1-(3-arylthioureido)ethyl)benzamides","authors":"Elizaveta R. Lominoga, P. Zadorozhnii, V. Kiselev, A. V. Kharchenko","doi":"10.3390/ecsoc-26-13538","DOIUrl":"https://doi.org/10.3390/ecsoc-26-13538","url":null,"abstract":": Derivatives of 1,3,5-oxadiazine are of interest to pharmacy, medicine, and agriculture as potential biologically active substances. These compounds have found wide application in organic synthesis and supramolecular chemistry. In this paper, we discuss and compare the effectiveness of two approaches to the dehydrosulfurization of 4-chloro-N -(2,2,2-trichloro-1-(3-arylthioureido)ethyl) benzamides resulting in the formation of 6-(4-chlorophenyl)- N -aryl-4-(trichloromethyl)-4 H -1,3,5-oxadiazin-2-amines. Dicyclohexylcarbodiimide (DCC) or a mixture of iodine with triethylamine was used as a dehydrosulfurizing agent. It is shown that, in the case of using DCC, the target products are predominantly formed in high yields. However, the use of the I 2 + Et 3 N mixture made it possible to obtain several new compounds of this class, which could not be obtained under the DCC action. The structure of all new compounds was confirmed by 1 H and 13 C NMR spectroscopy data.","PeriodicalId":255032,"journal":{"name":"The 26th International Electronic Conference on Synthetic Organic Chemistry","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124036543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yeneva Alves-Iglesias, P. Bermejo-Barrera, A. M. García-Deibe, M. Fondo, J. Sanmartín-Matalobos
: The Schiff base ligand H 2 SB derived from the condensation of N -(2-aminobenzyl)-5- (dimethylamino)naphthalene-1-sulfonamide with 4-formyl-3-hydroxybenzoic acid has been investigated as a chemosensor for the detection of CdSe-Cys QDs in water samples. We immobilized H 2 SB onto cellulose paper by forming an amide bond, which results from the condensation of a carboxylic acid and an amine. Three dominant signals located around 270, 330, and 420 nm in the diffuse reflectance spectrum of the H 2 SB-modified paper demonstrated its immobilization. A linear decrease can be observed in the absorbance of the 270 nm band with the increase of the CdSe-Cys QDs concentration from 100 ppb to 2 ppm. The LOD and LOQ show values of 245 and 815 ppb, respectively. An interaction via metal–ligand coordination between CdSe-Cys QDs and H 2 SB has been demonstrated with 1 H NMR, ATR-FTIR, and UV-Vis spectroscopy.
{"title":"Immobilization on Cellulose Paper of a Chemosensor for CdSe-Cys QDs","authors":"Yeneva Alves-Iglesias, P. Bermejo-Barrera, A. M. García-Deibe, M. Fondo, J. Sanmartín-Matalobos","doi":"10.3390/ecsoc-26-13561","DOIUrl":"https://doi.org/10.3390/ecsoc-26-13561","url":null,"abstract":": The Schiff base ligand H 2 SB derived from the condensation of N -(2-aminobenzyl)-5- (dimethylamino)naphthalene-1-sulfonamide with 4-formyl-3-hydroxybenzoic acid has been investigated as a chemosensor for the detection of CdSe-Cys QDs in water samples. We immobilized H 2 SB onto cellulose paper by forming an amide bond, which results from the condensation of a carboxylic acid and an amine. Three dominant signals located around 270, 330, and 420 nm in the diffuse reflectance spectrum of the H 2 SB-modified paper demonstrated its immobilization. A linear decrease can be observed in the absorbance of the 270 nm band with the increase of the CdSe-Cys QDs concentration from 100 ppb to 2 ppm. The LOD and LOQ show values of 245 and 815 ppb, respectively. An interaction via metal–ligand coordination between CdSe-Cys QDs and H 2 SB has been demonstrated with 1 H NMR, ATR-FTIR, and UV-Vis spectroscopy.","PeriodicalId":255032,"journal":{"name":"The 26th International Electronic Conference on Synthetic Organic Chemistry","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128653245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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