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ANALYSIS OF THE ACTUAL PRACTICE FOR OSTEOPENIA IN CHILDREN AND ADOLESCENTS 儿童和青少年骨质减少症的实际治疗分析
Pub Date : 2022-12-15 DOI: 10.30809/solo.4.2022.
V. A. Alekseeva, A. V. Ovsyankin, E.S. Kuzminova, A. V. Krikova, N. Krutikova, E. V. Dmitrieva
Goal. To analyze medical prescriptions in real practice in the treatment of children and adolescents with signs of osteopenia. Methods. A retrospective analysis of 44 medical records of patients aged 0 to 17 years, inclusive, with complaints characteristic of osteopenia, who were prescribed a 25(OH)D test. A content analysis of vitamin D preparations in the pharmaceutical market of the Russian Federation was carried out and the costs for 3 months of treatment were calculated. Results. 6 models of complex treatment of osteopenia in children and adolescents were formed, in relation to the diagnosis and the detected level of 25(OH)D. Each included vitamin D supplementation, a calcium-rich diet, and various physical therapy modalities. Treatment outcomes were monitored every 3 months based on X-ray data and blood 25(OH)D testing. It has been established that the cost of non-drug therapy is more than 80% of the total. The cost of paid treatment for various skel- etal deformities consists of the costs of medical services, non-drug and drug therapy and amounts to 25805.4 rubles. ± 488.1 rub. Conclusion. Real medical practice in the treatment of osteopenia in children and adolescents is based on current clinical algorithms and recommendations. The appointment of treatment is carried out not only on the basis of the diagnosis, but also the value of laboratory tests.
的目标。目的:分析儿童、青少年骨质减少症的临床用药情况。方法。回顾性分析44例年龄在0 - 17岁之间,以骨质减少为主诉的患者的医疗记录,并开具25(OH)D检查。对俄罗斯联邦药品市场上的维生素D制剂进行了含量分析,并计算了3个月的治疗费用。结果:根据诊断结果和25(OH)D检测水平,形成6种儿童青少年骨质减少综合治疗模型。其中包括补充维生素D、富含钙的饮食和各种物理治疗方式。根据x线数据和血液25(OH)D检测每3个月监测一次治疗结果。已经确定,非药物治疗的费用占总费用的80%以上。各种骨骼畸形的有偿治疗费用包括医疗服务、非药物治疗和药物治疗费用,共计25805.4卢布。±488.1搓。结论。在治疗儿童和青少年骨质减少的实际医疗实践是基于当前的临床算法和建议。治疗的安排不仅是根据诊断,而且还根据实验室检查的价值。
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引用次数: 0
CONCEPTUAL MODELS FOR THE FORMATION AND EVALUATION OF THE QUALITY OFPHARMACY ORGANIZATIONS 药学组织质量形成与评价的概念模型
Pub Date : 2022-12-15 DOI: 10.30809/solo.4.2022.3
A. G. Petrov, G. Glembotskaya, O. Khoroshilova, Y. Sashko, V. A. Semenikhin
The review considers conceptual models for the formation and evaluation of the quality of pharmacy organizations. The formation and evaluation of the quality of work of a pharmacy organization depends on a set of factors, in particular on the intellectual cap- ital of employees. It is shown that competitor management involves the use of such strategic components in the competition as the intellectual capital of employees of a pharmacy organization, contributing to the competitiveness of the organization in the pharmaceutical market and reducing risk events.
本综述考虑了药学组织质量形成和评价的概念模型。药房组织工作质量的形成和评价取决于一系列因素,尤其是员工的智力资本。研究表明,竞争对手管理涉及到在竞争中利用制药组织员工的智力资本等战略要素,有助于提高组织在制药市场中的竞争力,减少风险事件。
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引用次数: 0
STUDYING THE SOCIAL FUNCTION OF A PHARMACY IN A MULTILEVEL SYSTEM OF CITIZENS PREFERENTIAL MEDICATION PROVISION IN THE TYUMEN REGION 研究秋明地区多层次市民优先用药体系中药房的社会功能
Pub Date : 2022-12-15 DOI: 10.30809/solo.4.2022.4
N. D. Bredneva, N. P. Firsenko, A. Putintseva, L.V. Onegina, M.D. Vaganov, E. A. Sharshina
The purpose of the study: to study the activities of the pharmacy, a structural unit of JSC «Pharmacy» (Tyumen region) in terms of providing social pharmaceutical assistance to citizens. Materials and methods. The object of the study was the activities of Pharmacy No. 173, a structural unit of the joint-stock company «Pharmacy» in the Tyumen region, indicators of all areas of preferential medication provision for citizens, including a new direction for providing people who have had acute cardiovascular diseases, the amount of funds allocated from the budgets of all levels for the provision of medication care , data from the regional Register of Persons, volumes of dispensed medicines for the preferential category, the number of secured prescriptions, their average cost. The following methods were used in the study: situational-logi- cal, content analysis, structural, system, computer technologies. Results. The directed activity of the pharmacy of finished dosage forms to ensure the availability of drug assistance to privileged categories of citizens, its social significance, the indicators for the number of secured prescriptions, the volume of dispensing of preferential drugs, including those who have had acute cardiovascular diseases, have been studied. Pharmacy of finished dosage forms, which carries out pharmaceutical activities in the retail trade of medicines for medical use, storage, dispensing of medicines, performs an important social function in dispensing medicines by prescription for free or with a 50% discount from the cost, includ- ing state social assistance (34, 04% of the total volume of dispensing), medications as a measure of social support in the treatment of certain diseases (58.63%), expensive drugs for the treatment of 14 nosologies (2.92%), certain drugs for the treatment of people who have had acute heart vascular diseases (4.41%). To perform this function of drug supply, a specialized pharmacy department was organized, equipped with a software product for recording incoming prescriptions, including in electronic form, for creating registers of issued prescriptions, and recording the movement of preferential drugs. The activities are carried out by pharmacists, pharmacists - technologists trained in consulting on the provision of social assistance to certain categories of citizens To comply with the regulatory and legal regulation of the provision of this activity, the standard operating procedure (SOP) «Dispensing med- icines to preferential categories of citizens» is applied. The standard operating procedure describes the step-by-step procedure for dispensing medicines on prescriptions of medical professionals to citizens who are entitled to receive free or discounted medicines. Conclusion. It should be noted the undoubtedly significant role of the pharmacy, pharmaceutical workers in the system of providing benefits in the field of drug provision. The significant role is due to the need to have knowledge of the procedure
研究的目的是:研究JSC“药房”(秋明地区)的一个结构单位药房在向公民提供社会药品援助方面的活动。材料和方法。研究的对象是秋明地区“药房”股份公司的结构单位第173号药房的活动,为公民提供优惠药品的所有领域的指标,包括为患有急性心血管疾病的人提供服务的新方向,各级预算为提供药品服务拨出的资金数额,区域人口登记册的数据,为优惠类别分配的药品数量,有保障的处方数量,其平均费用。本研究采用情境逻辑分析、内容分析、结构分析、系统分析、计算机技术等方法。结果。研究了为确保向特权阶层公民提供药品援助而直接开展的成品剂型药房活动、其社会意义、获得处方的数量指标、特惠药物(包括患有急性心血管疾病的药物)的配发量。成品剂型药房在医疗用途、储存和配药的药品零售贸易中开展医药活动,在通过免费处方或价格折扣50%的方式配药方面发挥着重要的社会作用,包括国家社会援助(占配药总量的34,04%)、在治疗某些疾病时作为社会支持措施的药物(58.63%)。用于治疗14种疾病的昂贵药物(2.92%),用于治疗患有急性心血管疾病的某些药物(4.41%)。为了履行这一药品供应职能,成立了一个专门的药房,配备了一个软件产品,用于记录收到的处方,包括电子形式的处方,创建已开处方的登记册,并记录优惠药品的流动。这些活动是由药剂师,药剂师-在向某些类别的公民提供社会援助方面受过咨询培训的技术人员进行的。为了遵守提供这种活动的监管和法律规定,适用了标准操作程序(SOP)“向优先类别的公民分发药品”。标准作业程序描述了按照医疗专业人员的处方逐步向有权获得免费或折扣药品的公民配药的程序。结论。应该指出的是,药房无疑具有重要的作用,药学工作者在提供福利的制度领域提供药品。重要的角色是由于需要了解发放福利的程序,遵守向不同类别受益人分发特定药物清单的特殊规则的能力,掌握记录补贴药物的安全处方的现代技术的能力,与统一国家卫生信息系统(USIS health)中的医疗组织进行互动。在秋明地区,这些职能的专业履行在很大程度上有助于确定优惠药品提供的指标的稳定性,以及对药房在实施药学活动中的社会功能的认可。
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引用次数: 0
THE MAIN TRENDS IN THE POPULATION CONSUMPTION OF MEDICINES PRESCRIBED FOR ARTERIAL HYPERTENSION IN THE RUSSIAN FEDERATION 俄罗斯联邦动脉高血压处方药物人口消费的主要趋势
Pub Date : 2022-12-15 DOI: 10.30809/solo.4.2022.5
P. R. Blinkova
Arterial hypertension is a widespread disease and a major risk factor for the development of lethal cardiovascular pathologies. To reduce this risk, timely detection of arterial hypertension, control of blood pressure levels and effective drug therapy for high blood pressure are necessary. Relevance. Study of population consumption of drugs used for hypertension in the retail sector of the pharmaceutical market in the Russian Federation for the period from 2017 to 2021. Methods. We used the methods of retrospective, predictive, structural, logical, comparative, graphic, marketing, pharmacoepi- demiological analyzes when conducting this study. The results were processed using the normalization method and methods of mathematical statistics. Results. The analysis of the structure and study of the characteristics of the population consumption of drugs used for arterial hy- pertension in the territory of the Russian Federation for the period 2017-2021 was carried out. The main share of sales falls on monopreparations: 92.04% - in physical terms, 74.55% - in monetary terms. In the rare pharmacy sales of antihypertensive drugs in the Russian Federation, the share of fixed combinations is 7.96% in physical terms and 25.64% in monetary terms. The most popular antihypertensive drugs in both in-kind and monetary terms over the estimated period are ACE inhibitors and β-blockers. In the subgroup of fixed combinations, “angiotensin II receptor blocker + diuretic” and “ACE inhibitor + diuretic” are in the lead. In the total consumption of antihypertensive drugs, the share of multicomponent fixed combinations accounts for only 0.44% in physical terms, but in monetary terms this figure is 2.51%. According to the results of the survey, doctors were more likely to be conservative in prescribing antihypertensive drug therapy, preferring single drugs, and medical specialists receive information about new drugs mainly at conferences, when meeting with medical representatives, and also from the Internet. Conclusion. Based on the results of the study, an educational program for medical and pharmaceutical specialists “Modern range of drugs prescribed for the prevention and treatment of hypertension” was developed.
动脉高血压是一种广泛存在的疾病,也是致死性心血管疾病发展的主要危险因素。为了降低这种风险,及时发现动脉高血压,控制血压水平和有效的药物治疗高血压是必要的。的相关性。2017年至2021年期间俄罗斯联邦药品市场零售部门用于高血压的药物人口消费研究。方法。本研究采用回顾性分析、预测分析、结构分析、逻辑分析、比较分析、图表分析、市场分析、药物流行病学分析等方法。采用归一化方法和数理统计方法对结果进行处理。结果。对2017-2021年俄罗斯联邦境内用于动脉高血压的药物的人口消费结构和特征进行了分析和研究。销售的主要份额落在单一经营上:92.04%(以实物计算),74.55%(以货币计算)。在俄罗斯联邦罕见的降压药药房销售中,固定组合的实物销售份额为7.96%,货币销售份额为25.64%。在估计期间,最流行的抗高血压药物是ACE抑制剂和β受体阻滞剂。在固定组合亚组中,以“血管紧张素II受体阻滞剂+利尿剂”和“ACE抑制剂+利尿剂”为主。在降压药物的总消费中,多组分固定组合在物理上仅占0.44%,但在货币上这一数字为2.51%。根据调查结果,医生在开降压药物治疗处方时更倾向于保守,更倾向于单一药物,医学专家主要是在会议上、与医学代表会面时,以及从互联网上获得有关新药的信息。结论。根据研究结果,为医疗和制药专家制定了一项教育方案"预防和治疗高血压的现代处方药物范围"。
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引用次数: 0
RATIONAL TREATMENT OF ACUTERESPIRATORY VIRAL INFECTION USING THE DRUG SEPTOLETE® TOTAL 合理应用septolete®total治疗急性呼吸道病毒感染
Pub Date : 2022-12-15 DOI: 10.30809/solo.4.2022.1
E. E. Arinina, M. A. Rashid
Acute respiratory viral infections (ARVI) are the most common diseases of the human population. Due to the high virulence of pathogens, in some cases they can acquire the character of an epidemic or pandemic. The diversity of the clinical picture, the com- plexity of predicting outcomes makes the problem of rational choice of a drug for the primary treatment of acute respiratory viral infections a key one and poses a difficult task for the pharmacist - the correct, efficient, safe and effective use of a wide range of drugs available on the domestic pharmaceutical market for the treatment of acute respiratory viral infections. During the pharma- cy consultation, the pharmacist has to find out the patient’s complaints, his morbid background, the presence of drug intolerance, as well as a number of other factors, taking into account the pandemic of a new coronavirus infection. Medicines for the treatment of acute respiratory viral infections are presented in most cases as combination drugs that have several mechanisms of action. The possibility of influencing several manifestations of the disease is provided through the use of Septolete® Total, which has not only a favorable efficacy / safety profile, but also distinct economic advantages over analogues, as well as a potential virucidal effect against the causative agent of a new coronavirus COVID-19 infections.
急性呼吸道病毒感染(ARVI)是人类最常见的疾病。由于病原体的高毒力,在某些情况下,它们可以获得流行病或大流行的特征。临床情况的多样性,预测结果的复杂性,使得合理选择用于急性呼吸道病毒感染初级治疗的药物成为一个关键问题,也是药剂师面临的一项艰巨任务——正确、高效、安全、有效地使用国内医药市场上广泛的治疗急性呼吸道病毒感染的药物。在药房咨询期间,药剂师必须考虑到新型冠状病毒感染的大流行,找出患者的抱怨,他的病态背景,药物不耐受的存在,以及许多其他因素。在大多数情况下,治疗急性呼吸道病毒感染的药物是具有几种作用机制的联合药物。通过使用Septolete®Total,可以影响疾病的几种表现,该药物不仅具有良好的疗效/安全性,而且与类似物相比具有明显的经济优势,并且对新型冠状病毒COVID-19感染的病原体具有潜在的病毒杀伤作用。
{"title":"RATIONAL TREATMENT OF ACUTERESPIRATORY VIRAL INFECTION USING THE DRUG SEPTOLETE® TOTAL","authors":"E. E. Arinina, M. A. Rashid","doi":"10.30809/solo.4.2022.1","DOIUrl":"https://doi.org/10.30809/solo.4.2022.1","url":null,"abstract":"Acute respiratory viral infections (ARVI) are the most common diseases of the human population. Due to the high virulence of pathogens, in some cases they can acquire the character of an epidemic or pandemic. The diversity of the clinical picture, the com- plexity of predicting outcomes makes the problem of rational choice of a drug for the primary treatment of acute respiratory viral infections a key one and poses a difficult task for the pharmacist - the correct, efficient, safe and effective use of a wide range of drugs available on the domestic pharmaceutical market for the treatment of acute respiratory viral infections. During the pharma- cy consultation, the pharmacist has to find out the patient’s complaints, his morbid background, the presence of drug intolerance, as well as a number of other factors, taking into account the pandemic of a new coronavirus infection. Medicines for the treatment of acute respiratory viral infections are presented in most cases as combination drugs that have several mechanisms of action. The possibility of influencing several manifestations of the disease is provided through the use of Septolete® Total, which has not only a favorable efficacy / safety profile, but also distinct economic advantages over analogues, as well as a potential virucidal effect against the causative agent of a new coronavirus COVID-19 infections.","PeriodicalId":266512,"journal":{"name":"Modern organization of drug supply","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126993301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
AVAILABILITY ANALYSIS OF ORAL ANTIPLATELETS IN THE RUSSIAN FEDERATION 俄罗斯联邦口服抗血小板药物的可用性分析
Pub Date : 2022-06-15 DOI: 10.30809/solo.2.2022.3
M. Abdullaev, E. Orlova, B. Kantemirova, A. I. Grechukhin
Abstract The Aim. Pharmacoeconomic assessment of the oral antiplatelet availability of various drug manufacturers and dosage forms based on the analysis of price characteristics. Materials and methods. The analysis included drugs from the group of platelet aggregation inhibitors (excluding heparin) (ATC code B01AC): clopidogrel, clopidogrel + acetylsalicylic acid (ASA), ASA and dipyridamole in various dosages and number of tablets per package. The cost values were estimated by the resources of large resources "Apteka.ru", "009.rf" with the average value calculations in the eight federal district’s capitals of the country. Results. The cost of drugs in the analyzed group varied depending on the drug manufacturer. The highest amount of the cost variation was in the ASA tablet form (100 mg) – 407.47%, followed by the tablet form of clopidogrel (75 mg) – 311.16%, ASA (50 mg) – 172.20%, dipyridamole (75 mg) – 117.36% and the lowest values for the tablet forms of dipyridamole (25 mg) – 68.19% and the combination of ASA with clopidogrel (100mg + 75mg) – 59.13%. The highest Ca.s values were in ticagrelor (90 mg) – 24.92% and prasugrel (10 mg) – 7.87%, the lowest in ASA (50 mg) – 0.1%. According to the linear index of distribution, the drugs ASA (100 mg) – 89%, clopidogrel (75 mg) – 70%, and less accessible ticagrelor (60 mg) – 18% and prasugrel (10 mg) – 14% had a higher physical availability. Conclusion. Based on the calculated values a high availability of such antiplatelet drugs as ASA (50 mg and 100 mg), clopidogrel (75 mg) was revealed. According to the results of the study, the antiplatelet drugs ticagrelor (60 mg and 90 mg) and prasugrel (10 mg) have the least level of availability.
目的。基于价格特征分析的口服抗血小板药物的经济评价。材料和方法。分析的药物来自血小板聚集抑制剂组(不包括肝素)(ATC代码B01AC):氯吡格雷、氯吡格雷+乙酰水杨酸(ASA)、ASA和双嘧达莫,不同剂量和每包片数。成本值是根据大型资源“Apteka.ru”,“009”的资源估算的。Rf”,以该国八个联邦区首府的平均值计算。结果。所分析组的药物成本因药品制造商而异。ASA片剂价格变动幅度最大(100mg)为407.47%,其次为氯吡格雷片剂(75 mg)为311.16%,ASA片剂(50 mg)为172.20%,双嘧达莫片剂(75 mg)为117.36%,双嘧达莫片剂(25 mg)为68.19%,ASA与氯吡格雷合用(100mg + 75mg)为59.13%。Ca.s值以替格瑞洛(90 mg)和普拉格雷(10 mg)最高,分别为24.92%和7.87%,ASA最低,分别为50 mg和0.1%。根据线性分布指数,ASA (100 mg) - 89%,氯吡格雷(75 mg) - 70%,较难获得的替格瑞洛(60 mg) - 18%,普拉格雷(10 mg) - 14%具有较高的物理利用度。结论。根据计算值,ASA (50 mg和100 mg)、氯吡格雷(75 mg)等抗血小板药物具有较高的可用性。根据研究结果,抗血小板药物替格瑞洛(60mg和90mg)和普拉格雷(10mg)的可用性最低。
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引用次数: 0
INTERNET SERVICES OF PHARMACY CHAINS AS A TOOL OF PHARMACEUTICAL EDUCATION OF THE POPULATION: RELEVANCE, PROBLEMS, SOLUTIONS 连锁药店的互联网服务作为人口药学教育的工具:相关性、问题、解决方案
Pub Date : 2022-06-15 DOI: 10.30809/solo.2.2022.4
T. Shestakova, I. Kirshchina
PURPOSE. Study of the potential of pharmacy chains for the development of pharmaceutical literacy of the population through Internet and online resources. METHODS. The objects of the analysis were the Internet sites and online services of the largest pharmacy chains and services for remote ordering of pharmacy assortment goods (TOP 20). The basis for inclusion in the analysis was the data of the analytical agencies DSM Group, RNC Pharma and AlphaRM. Methods of criteria, logical, comparative and content analysis were used to conduct the study. The authors have developed their own evaluation scale focused on evaluating the content of the Internet sites of pharmacy chains in relation to the information and educational component for the population. RESULTS. Based on the consolidation of data from 3 analytical agencies, the final list of objects of analysis included 18 pharmacy chains and 3 services for remote ordering of pharmacy assortment goods. The average score on the evaluation scale for the totality of pharmacy chains was 9.13±0,74 out of 23 possible. The presence of websites and telephone help service for all objects of research, their features are revealed. The assessment of the availability and information content of mobile applications of pharmacy chains was carried out. The analysis of the information content of pharmacy networks in social networks and Internet messengers was carried out. Conclusions are made about the quantitative and qualitative component of the service for the population "Question – answer". The presence and features of information and educational materials for the population on the Internet sites of pharmacy chains are analyzed. A study of instructions for the medical use of medicines was conducted: quantitative components, relevance, compliance with the State Register of Medicines of the Russian Federation. CONCLUSION. The conducted research allowed us to draw conclusions about the insufficient degree of involvement of pharmacy chains in the process of pharmaceutical education of the population and the insignificant use of the possibility of influence of pharmacy chains on the development of pharmaceutical literacy of the population through Internet resources. The article provides recommendations on possible ways to fully develop pharmaceutical education of the population in the Internet space.
目的。研究连锁药店通过互联网和在线资源发展人口药学素养的潜力。方法。分析的对象是最大的连锁药店的互联网站点和在线服务,以及药房分类商品的远程订购服务(前20名)。纳入分析的基础是分析机构DSM Group, RNC Pharma和AlphaRM的数据。采用标准分析法、逻辑分析法、比较分析法和内容分析法进行研究。作者开发了自己的评估量表,侧重于评估连锁药店网站的内容与人口信息和教育成分的关系。结果。在对3家分析机构的数据进行整合后,最终的分析对象包括18家连锁药店和3家远程订购药品分类商品的服务。连锁药店总体评价量表的平均得分为9.13±0.74分(满分23分)。网站和电话帮助服务的存在为所有的研究对象,他们的特点被揭示出来。对连锁药店移动应用程序的可用性和信息含量进行了评估。对药店网络在社交网络和网络信使中的信息内容进行了分析。对人口“问答”服务的定量和定性组成部分进行了总结。分析了连锁药店网站上面向人群的信息教育资料的存在和特点。对药品的医疗使用说明进行了研究:数量组成、相关性、遵守俄罗斯联邦国家药品登记册。结论。通过所进行的研究,我们得出了连锁药店在人口药学教育过程中的参与程度不足以及通过互联网资源利用连锁药店影响人口药学素养发展的可能性的结论。文章就如何在互联网环境下充分开展人群药学教育提出了建议。
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引用次数: 0
ANALYSIS OF LEGAL ACTS REGULATINGHOSPITAL PHARMACY IN RUSSIA 俄罗斯规范医院药房的法律行为分析
Pub Date : 2022-06-15 DOI: 10.30809/solo.2.2022.1
V. Zubkov, R. Yagudina
To Develop classification of legal acts regulating the activities of hospital pharmacies and identify significant problems in them for drug provision enhancement in health facilities. Methods The main regulatory framework governing the hospital pharmacies activities was carried out using the computer help system "Con- sultant Plus" and Internet search engines Google and Yandex. The first group (group No. 1) includes terms that affect the actual subject of the study – hospital pharmacy and synonyms. The second group of words used (group No. 2) is common terms of hospital pharmacy activities and drug supply in the health facilities. Results We developed classification of regulatory legal acts that regulate the work of hospital pharmacies by the method of regulation (regulating directly and indirectly) and by content (regulating general aspects and applied aspects of drug provision in the health facility. Regulations governing general aspects, the definition of the hospital pharmacy as a pharmacy organization, the classifi- cation of pharmacy organizations, the status of a hospital pharmacy, the list of goods provided by a hospital pharmacy, as well as pharmaceutical works performed. Legal acts regulating applied aspects include groups of documents regulating the main process- es (drug supply) and regulating the supporting processes (personnel policy, provision of material and technical resources). Conclusion We identified non-regulated stages of drug supply specific for health facilities. In connection with the abolition of Soviet period legal acts important issues, personal and material and technical resources, were excluded from the legal framework, which was not compensated by the emergence of relevant legal acts. To date, a systematic approach has not been developed in the legal regula- tion of the hospital pharmacy, there is no continuity of legal acts and uniformity of terminology.
制定规范医院药房活动的法律行为分类,并查明其中的重大问题,以加强保健设施的药品供应。方法利用计算机帮助系统“咨询+”和互联网搜索引擎Google和Yandex,对医院药房活动进行主要监管框架。第一组(第1组)包括影响研究实际主题的术语——医院药学和同义词。第二组使用的词汇(第2组)是医院药房活动和卫生设施中药物供应的常用术语。结果:我们制定了监管法律行为分类,通过监管方法(直接和间接监管)和内容(监管卫生设施中药物供应的一般方面和应用方面)来规范医院药房的工作。管理一般方面的条例,医院药房作为药房组织的定义,药房组织的分类,医院药房的地位,医院药房提供的商品清单,以及所进行的药学工作。规范应用方面的法律行为包括规范主要过程(药品供应)和规范辅助过程(人事政策、物质和技术资源的提供)的文件组。结论:我们确定了针对卫生设施的非管制药品供应阶段。关于废除苏联时期的法律行为,重要的问题,个人和物质和技术资源,被排除在法律框架之外,这没有得到有关法律行为的补偿。迄今为止,医院药房的法律规制尚未形成系统的方法,法律行为没有连续性,术语也不统一。
{"title":"ANALYSIS OF LEGAL ACTS REGULATINGHOSPITAL PHARMACY IN RUSSIA","authors":"V. Zubkov, R. Yagudina","doi":"10.30809/solo.2.2022.1","DOIUrl":"https://doi.org/10.30809/solo.2.2022.1","url":null,"abstract":"To Develop classification of legal acts regulating the activities of hospital pharmacies and identify significant problems in them for drug provision enhancement in health facilities. Methods The main regulatory framework governing the hospital pharmacies activities was carried out using the computer help system \"Con- sultant Plus\" and Internet search engines Google and Yandex. The first group (group No. 1) includes terms that affect the actual subject of the study – hospital pharmacy and synonyms. The second group of words used (group No. 2) is common terms of hospital pharmacy activities and drug supply in the health facilities. Results We developed classification of regulatory legal acts that regulate the work of hospital pharmacies by the method of regulation (regulating directly and indirectly) and by content (regulating general aspects and applied aspects of drug provision in the health facility. Regulations governing general aspects, the definition of the hospital pharmacy as a pharmacy organization, the classifi- cation of pharmacy organizations, the status of a hospital pharmacy, the list of goods provided by a hospital pharmacy, as well as pharmaceutical works performed. Legal acts regulating applied aspects include groups of documents regulating the main process- es (drug supply) and regulating the supporting processes (personnel policy, provision of material and technical resources). Conclusion We identified non-regulated stages of drug supply specific for health facilities. In connection with the abolition of Soviet period legal acts important issues, personal and material and technical resources, were excluded from the legal framework, which was not compensated by the emergence of relevant legal acts. To date, a systematic approach has not been developed in the legal regula- tion of the hospital pharmacy, there is no continuity of legal acts and uniformity of terminology.","PeriodicalId":266512,"journal":{"name":"Modern organization of drug supply","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129406670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
STUDYING THE PROBLEMS OF DOSING INJECTABLE DRUGS DRUGS FOR GENERAL ANESTHESIA IN SURGICAL INTERVENTIONS IN CHILDREN 儿童外科手术中全麻注射用药问题的探讨
Pub Date : 2022-03-15 DOI: 10.30809/solo.1.2022.1
Yu. A. Abdullina, S. N. Egorova
The purpose of the study was to analyze the problems of dosing injectable drugs for general anesthesia in a pediatric surgical hospital. Methods: questioning, logical analysis, economic modeling. Results: As a result of a survey of anesthesiologists at a pediatric surgical hospital, problems with dosing drugs for general anesthesia for children in a pediatric surgical hospital were identified, due to the lack of special pediatric dosages and concentrations of injectable drugs. Injectable drugs have been identified that cause difficulties in individual dosing for children due to the lack of the required form of release: INN fentanyl (ampoules), propofol, ketamine, rocuronium bromide (ampoules and vials). Losses in the primary packaging of these medicines with a single use in young children are up to 50%-90%, which leads to both material losses and environmental risks when disposing of residues. An analysis of instructions for medical use showed that pharmaceutical manufacturers do not provide for an indication of the period and conditions for storing these medicinal products after the first opening of the vial. Conclusion: A set of proposals has been developed to optimize the circulation of injectable drugs for general anesthesia used in children: the advantages of using drugs in vials compared to ampoules are shown, and the primary packaging “vial” for fentanyl solution for injections is recommended; recommended the introduction of a requirement for registration of injectable drugs for general anesthesia in vials to indicate the period and storage conditions after the first opening of the primary packaging; on the label applied to the primary packaging, it is necessary to indicate the date and time of opening the vial;in the registration dossier of injectable medicinal products for general anesthesia, it is necessary to provide data confirming the stability after the first puncture of the capping of the vial during the recommended period and storage conditions of the medicinal product.
本研究旨在分析某儿科外科医院全麻注射用药中存在的问题。方法:提问、逻辑分析、经济建模。结果:通过对某儿科外科医院麻醉师的调查,发现了某儿科外科医院儿童全身麻醉用药存在的问题,原因是缺乏儿科专用的注射药物剂量和浓度。由于缺乏所需的释放形式,已确定对儿童个体给药造成困难的注射药物:非甾体芬太尼(安瓿)、异丙酚、氯胺酮、罗库溴铵(安瓿和小瓶)。这些儿童单次使用的药物的初级包装损失高达50%-90%,这在处理残留物时导致材料损失和环境风险。对医疗使用说明的分析表明,药品制造商在首次打开小瓶后没有提供这些药品的储存期限和条件的指示。结论:为优化儿童全身麻醉注射用药物的流通提出了一套建议:显示了使用小瓶药物相对于安瓿药物的优势,并推荐芬太尼注射剂的初级包装“小瓶”;建议引入全麻注射用小瓶药品注册要求,标明首次打开主包装后的期限和储存条件;在主包装上的标签上,需要注明开瓶日期和时间;在全麻注射用药品注册档案中,需要提供确认在推荐期限内第一次穿刺瓶盖后的稳定性和药品储存条件的数据。
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引用次数: 0
PREDICTORS OF HEALTH-SAVING, MEDICAL AND PHARMACEUTICAL CARE FOR PATIENTS WITH CHRONIC DISEASES (ON THE EXAMPLE OF PATIENTS WITH DIABETES MELLITUS) 慢性病患者保健、医疗和药学护理的预测因素(以糖尿病患者为例)
Pub Date : 2022-03-15 DOI: 10.30809/solo.1.2022.2
I. A. Kirshcina, A. Karimova, A. Soloninina
The organization of activities for the formation of sanitary literacy of patients with chronic diseases is a socially significant problem, which is very important for patients of the older age group who have many chronic diseases. When analyzing data compliance, it is necessary to identify and take into account the influence of a number of health-saving predictors. The aim of the study is to conduct a multifactorial analysis of health-saving predictors for patients with chronic diseases and to develop methodological foundations for the organization of their medical and pharmaceutical support. Materials and methods. The study of health-saving predictors for patients with chronic diseases was conducted on the basis of the results of an assessment of the behavior and lifestyle of patients with type 2 diabetes mellitus. The empirical database is formed by the results of a survey of 411 patients. Methods of statistical analysis using software products Statistica 10, Microsoft Excel were used. Methods of mathematical statistics were used (Student's two-sample test to assess significant intergroup differences; analysis of average ranks and analysis of variance). Results and discussion. By means of multivariate analysis of health-saving predictors for patients with diabetes mellitus, the most significant parameters of health-saving of patients with chronic diseases have been identified. The systematization of predictors on the basis of "controllability" was carried out. Unmanageable predictors of a patient's health include gender, age, level of education and income; conditionally controlled predictors include the functional state of the body, the presence of comorbidity and/or polymorbidity, the severity of polypragmasia, the duration of the disease; controlled predictors include the level of sanitary literacy and patient compliance, the presence of self-control skills of the disease, the level of social adaptation and the lifestyle. Conclusion. A logical and functional model of strategic management of medical and pharmaceutical care for patients with chronic diseases has been developed and a generalizing cumulative indicator (patient's health saving coefficient) has been formed on the basis of controlled predictors of health saving, which allows to evaluate the health saving potential of a particular patient.
慢性病患者卫生素养形成活动的组织是一个具有社会意义的问题,对于慢性病较多的老年群体患者来说非常重要。在分析数据遵从性时,有必要确定并考虑到一些节省健康的预测因素的影响。这项研究的目的是对慢性病患者挽救健康的预测因素进行多因素分析,并为组织他们的医疗和药物支助发展方法学基础。材料和方法。在对2型糖尿病患者的行为和生活方式进行评估的基础上,对慢性病患者的健康预测因素进行了研究。实证数据库是通过对411名患者的调查结果形成的。统计分析方法采用Statistica 10、Microsoft Excel等软件。采用数理统计方法(学生双样本检验评估组间显著差异;平均秩分析和方差分析)。结果和讨论。通过对糖尿病患者健康状况的多变量预测分析,确定了慢性病患者健康状况的最显著参数。在“可控性”的基础上,对预测因子进行了系统化处理。无法控制的病人健康预测因素包括性别、年龄、教育水平和收入;有条件控制的预测因素包括身体的功能状态、合并症和/或多发性疾病的存在、多语用症的严重程度、疾病的持续时间;控制预测因素包括卫生知识水平和患者依从性,疾病自控能力的存在,社会适应水平和生活方式。结论。建立了慢性病患者医疗和药物保健战略管理的逻辑和功能模型,并在健康储蓄控制预测因子的基础上形成了一个一般化的累积指标(患者健康储蓄系数),可以评估特定患者的健康储蓄潜力。
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引用次数: 0
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Modern organization of drug supply
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