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2014 IEEE 16th International Conference on e-Health Networking, Applications and Services (Healthcom)最新文献

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Inter-institutional protocol describing the use of three-dimensional printing for surgical planning in a patient with childhood epilepsy: From 3D modeling to neuronavigation 描述在儿童癫痫患者手术计划中使用三维打印的机构间协议:从3D建模到神经导航
C. Rondinoni, V. Souza, R. Matsuda, A. Peres, M. Santos, O. B. Filho, A. C. Santos, H. Machado, P. Noritomi, Jorge Silva
This study is the first step in an effort to develop three-dimensional (3D) printing for use in pediatric surgical planning. In order to accomplish this, we established an effective collaboration between Ribeirao Preto Clinics Hospital (HCRP) and Renato Archer Center for Information Technology (CTI). Printed biomodels can be used to support discussions, decision-making, and neuronavigation before surgery. The main purpose of 3D printing for specific case handling is to reduce damage by enhancing knowledge of orientation during surgical planning and personnel training before surgery. Here, we produced an object that represented the brain and face segment of a patient via additive manufacturing technology based on magnetic resonance imaging (MRI) data. Specific landmarks were measured by three distinct methods: manual caliper, an InVesalius software measurement tool, and neuronavigation coordinate detection. The mean coefficient of variation was 7.17% between all methods and landmarks measured. Our results validate the combined use of biomodels with InVesalius software tools for the assessment of individual brain anatomy facilitating manual handling and visualization of 3D models. The establishment of communication protocols between the teams involved, as well as navigation protocols for quality control, presents the possibility of developing long term training programs, and promotes the congregation of individuals from research areas in Medical Physics, Medical Sciences, and Neuroscience.
这项研究是开发用于儿科手术计划的三维(3D)打印技术的第一步。为了实现这一目标,我们在里贝罗普雷图诊所医院(HCRP)和雷纳托阿彻信息技术中心(CTI)之间建立了有效的合作关系。打印的生物模型可用于在手术前支持讨论、决策和神经导航。3D打印用于具体病例处理的主要目的是通过增强手术计划期间的定向知识和术前人员培训来减少损伤。在这里,我们通过基于磁共振成像(MRI)数据的增材制造技术制作了一个代表患者大脑和面部部分的物体。通过三种不同的方法测量特定的地标:手动卡尺,InVesalius软件测量工具和神经导航坐标检测。所有方法与测量的标志之间的平均变异系数为7.17%。我们的研究结果验证了生物模型与InVesalius软件工具的结合使用,以评估个体大脑解剖结构,促进手动处理和3D模型的可视化。在相关团队之间建立通信协议,以及质量控制的导航协议,提供了开发长期培训计划的可能性,并促进了来自医学物理学、医学科学和神经科学研究领域的个人的聚集。
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引用次数: 6
Informatics to support patient choice between diverse medical systems 信息学支持患者选择不同的医疗系统
Isaac Golden, A. Stranieri, T. Sahama, S. Pilapitiya, Sisira Siribaddana, Stephen Vaughan
Culturally, philosophically and religiously diverse medical systems including Western medicine, Traditional Chinese Medicine, Ayurvedic Medicine and Homeopathic Medicine, once situated in places and times relatively unconnected from each other, currently co-exist to a point where patients must choose which system to consult. These decisions require comparative analyses, yet the divergence in key underpinning assumptions is so great that comparisons cannot easily be made. However, diverse medical systems can be meaningfully juxtaposed for the purpose of making practical decisions if relevant information is presented appropriately. Information regarding privacy provisions inherent in the typical practice of each medical system is an important element in this juxtaposition. In this paper the information needs of patients making decisions regarding the selection of a medical system, are examined.
包括西医、中医、阿育吠陀医学和顺势疗法在内的文化、哲学和宗教多样化的医疗体系,曾经位于彼此相对不相关的地方和时间,目前却共存到患者必须选择咨询哪个系统的程度。这些决定需要比较分析,但关键基础假设的差异如此之大,以至于不容易进行比较。然而,如果适当地提供相关信息,可以将不同的医疗系统有意义地并置,以便做出实际的决定。关于每个医疗系统的典型实践中固有的隐私规定的信息是这种并置的重要元素。在这篇论文中,研究了患者在选择医疗系统时的信息需求。
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引用次数: 1
Analysis of visually guided tracking performance in Parkinson's disease 帕金森病患者视觉引导跟踪效果分析
Yi Liu, Chonho Lee, Bu-Sung Lee, James K. R. Stevenson, M. McKeown
Recent studies have suggested significant differences in motor performances of Parkinson's Disease (PD) patients who have L-dopa induced dyskinesias (LIDs), even when off of L-dopa medication. The pathophysiology of LIDs remains obscure, so applying data-mining techniques to the patients' motor performance may provide some heuristic insight. This paper investigated visually-guided tracking performance of PD patients using data mining techniques to reveal the differences between dyskinesia and non-dyskinesia patients. We found that K-means clustering of the root mean square (RMS) tracking error at faster tracking speeds and with ambiguous visual stimuli was able to effectively discriminate between the two groups with 77.8% accuracy. Decision tree classification was less accurate (68.4%) and determined that years since diagnosis was the best feature to distinguish between groups. Our results suggest that data mining methodologies may provide novel insights into features of the neurovegetative disease.
最近的研究表明,患有左旋多巴诱导的运动障碍(lid)的帕金森病(PD)患者的运动表现存在显著差异,即使在停用左旋多巴药物时也是如此。眼睑的病理生理学仍然不清楚,因此将数据挖掘技术应用于患者的运动表现可能会提供一些启发式的见解。本文使用数据挖掘技术研究PD患者的视觉引导跟踪表现,以揭示运动障碍患者与非运动障碍患者之间的差异。我们发现,在更快的跟踪速度和模糊的视觉刺激下,根均方跟踪误差的k -均值聚类能够有效地区分两组,准确率为77.8%。决策树分类的准确性较低(68.4%),并确定自诊断以来的年份是区分组间的最佳特征。我们的研究结果表明,数据挖掘方法可能为神经植物性疾病的特征提供新的见解。
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引用次数: 3
Elements of a real-time vital signs monitoring system for players during a football game 足球比赛中球员实时生命体征监测系统的组成部分
S. Hara, T. Tsujioka, Takunori Shimazaki, Kouhei Tezuka, Masayuki Ichikawa, Masato Ariga, Hajime Nakamura, Takashi Kawabata, Kenji Watanabe, M. Ise, Noa Arime, H. Okuhata
We have developed a real-time vital signs monitoring system for two years in 2012 and 2013. Just by putting a single vital sensor node to the back waist position of each player and placing four data collection nodes around a field, the system can monitor at a note PC heart rate (HR), energy expenditure (EE) and body temperature (BT) for all players during a football game in real-time, periodically and reliably. The system is based on novel vital sensing technique and wireless data transmission technique. This paper introduces the two techniques in the system, presents some problems encountered in the system development and discusses solutions for them.
我们在2012年和2013年开发了两年的实时生命体征监测系统。只需将单个重要传感器节点放置在每个球员的后腰位置,并在场地周围放置四个数据收集节点,该系统就可以实时、定期、可靠地监测足球比赛中所有球员的心率(HR)、能量消耗(EE)和体温(BT)。该系统基于新颖的生命传感技术和无线数据传输技术。本文介绍了这两种技术在系统中的应用,提出了系统开发中遇到的一些问题,并讨论了解决这些问题的方法。
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引用次数: 11
Effects of electrode configurations in transcranial direct current stimulation after stroke 脑卒中后经颅直流电刺激中电极配置的影响
K. Chelette, Cheryl Carrico, L. Nichols, Emily Salyers, L. Sawaki
Transcranial direct current stimulation (tDCS) is a form of non-invasive brain stimulation that can modulate neuroplasticity (the capacity for brain reorganization). Neuroplastic change correlates with upper extremity (UE) recovery after brain lesions. Different electrode configurations of tDCS paired with UE motor training can have different effects in distinct populations. We are conducting the first randomized, double-blind, placebo-controlled trial to investigate which tDCS configuration may best enhance outcomes of UE motor training for stroke survivors with chronic, severe hemiparesis (i.e., little or no wrist or hand movement). We have assigned subjects to 1 of 4 groups: 1) “Anodal”: anodal tDCS to excite ipsilesional motor cortex; 2) “Cathodal”: cathodal tDCS to inhibit contralesional motor cortex; 3) “Dual”: a simultaneous combination of anodal and cathodal tDCS; or 4) “Sham” tDCS. Intervention (10 sessions) consists of tDCS followed by 3 hours of intensive, task-oriented UE training in each session. Our primary outcome measure is Fugl-Meyer Assessment. Our secondary outcome measures are Action Research Arm Test and Stroke Impact Scale. We have conducted evaluations at baseline and post-intervention. Preliminary results from 26 of (projected) 44 subjects indicate substantially greater improvement for the “Cathodal” group than other groups. These findings differ from evidence about tDCS in rehabilitation of mild-to-moderate hemiparesis. Completion of our study will include full analysis of neuroplastic change associated with intervention.
经颅直流电刺激(tDCS)是一种非侵入性脑刺激,可以调节神经可塑性(大脑重组的能力)。脑损伤后神经可塑性改变与上肢(UE)恢复相关。tDCS与UE运动训练相结合的不同电极配置在不同人群中具有不同的效果。我们正在进行第一项随机、双盲、安慰剂对照试验,以研究哪种tDCS配置可以最好地提高患有慢性严重偏瘫(即很少或没有手腕或手运动)的中风幸存者的UE运动训练结果。我们将受试者分为4组:1)“阳极”:通过阳极tDCS刺激同侧运动皮层;2)“负向”:负向tDCS抑制对侧运动皮层;3)“双”:同时结合阳极和阴极tDCS;或4)“假”tDCS。干预(10个疗程)包括tDCS,然后是每个疗程3小时的任务导向的强化UE培训。我们的主要结果测量是Fugl-Meyer评估。我们的次要结果测量是行动研究臂测试和中风影响量表。我们在基线和干预后进行了评估。对44名(预计)受试者中的26名进行的初步结果表明,“天主教”组比其他组有更大的改善。这些发现与tDCS在轻中度偏瘫康复中的证据不同。完成我们的研究将包括与干预相关的神经可塑性变化的全面分析。
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引用次数: 4
An ECG monitoring system for prediction of cardiac anomalies using WBAN 一种基于WBAN的心电监测系统
Medina Hadjem, Osman Salem, Farid Naït-Abdesselam
Cardiovascular diseases (CVD) are known to be the most widespread causes to death. Therefore, detecting earlier signs of cardiac anomalies is of prominent importance to ease the treatment of any cardiac complication or take appropriate actions. Electrocardiogram (ECG) is used by doctors as an important diagnosis tool and in most cases, it's recorded and analyzed at hospital after the appearance of first symptoms or recorded by patients using a device named holter ECG and analyzed afterward by doctors. In fact, there is a lack of systems able to capture ECG and analyze it remotely before the onset of severe symptoms. With the development of wearable sensor devices having wireless transmission capabilities, there is a need to develop real time systems able to accurately analyze ECG and detect cardiac abnormalities. In this paper, we propose a new CVD detection system using Wireless Body Area Networks (WBAN) technology. This system processes the captured ECG using filtering and Undecimated Wavelet Transform (UWT) techniques to remove noises and extract nine main ECG diagnosis parameters, then the system uses a Bayesian Network Classifier model to classify ECG based on its parameters into four different classes: Normal, Premature Atrial Contraction (PAC), Premature Ventricular Contraction (PVC) and Myocardial Infarction (MI). The experimental results on ECGs from real patients databases show that the average detection rate (TPR) is 96.1% for an average false alarm rate (FPR) of 1.3%.
众所周知,心血管疾病(CVD)是最普遍的死亡原因。因此,发现心脏异常的早期迹象对于缓解任何心脏并发症的治疗或采取适当的措施具有重要意义。心电图(Electrocardiogram, ECG)被医生作为一种重要的诊断工具,在大多数情况下,它是在首次症状出现后在医院记录和分析的,或者是由患者使用一种名为动态心电图(holter ECG)的设备记录并由医生进行分析。事实上,目前缺乏能够在严重症状出现之前远程捕捉心电图并进行分析的系统。随着具有无线传输能力的可穿戴传感器设备的发展,需要开发能够准确分析ECG并检测心脏异常的实时系统。本文提出了一种基于无线体域网络(WBAN)技术的CVD检测系统。该系统利用滤波和未消差小波变换(UWT)技术对采集到的心电信号进行处理,去除噪声,提取9个主要心电诊断参数,然后利用贝叶斯网络分类器模型将心电信号根据参数分为正常、房性早搏(PAC)、室性早搏(PVC)和心肌梗死(MI) 4类。实验结果表明,平均检测率(TPR)为96.1%,平均虚警率(FPR)为1.3%。
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引用次数: 40
An integrated approach of diet and exercise recommendations for diabetes patients 糖尿病患者饮食和运动建议的综合方法
Irshad Faiz, H. Mukhtar, Sharifullah Khan
Diabetes is among one of the fastest growing disease all over the world. Controlled diet and proper exercise are considered as a treatment to control diabetes. However, food and exercise suggestions in existing solutions do not consider integrated knowledge from personal profile, preferences, current vital signs, diabetes domain, food domain and exercise domain. Furthermore, there is a strong correlation of diet and exercise. We have implemented an ontology based integrated approach to combine knowledge from various domains to generate diet and exercise suggestions for diabetics. The solution is developed as a Semantic Healthcare Assistant for Diet and Exercise (SHADE). For each domain (person, diabetes, food and exercise) we have defined separate ontology along with rules and then an integrated ontology combines these individual ontologies. Finally, diet recommendations are presented in the form of various alternative menus such that each menu is a healthy and balanced diet.
糖尿病是世界上增长最快的疾病之一。控制饮食和适当运动被认为是控制糖尿病的一种治疗方法。然而,现有解决方案中的饮食和运动建议没有综合考虑个人概况、偏好、当前生命体征、糖尿病领域、饮食领域和运动领域的知识。此外,饮食和锻炼也有很强的相关性。我们实现了一种基于本体的集成方法,将不同领域的知识结合起来,为糖尿病患者生成饮食和运动建议。该解决方案是作为饮食和运动的语义医疗保健助手(SHADE)开发的。对于每个领域(人、糖尿病、食物和运动),我们定义了单独的本体和规则,然后将这些单独的本体结合在一起,形成一个集成的本体。最后,饮食建议以各种替代菜单的形式呈现,以便每个菜单都是健康和均衡的饮食。
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引用次数: 19
Limitations of principal component analysis as a method to detect neuronal assemblies 主成分分析作为一种检测神经元集合的方法的局限性
C. S. Deolindo, A. Kunicki, F. Brasil, R. Moioli
The anatomical and functional characterization of neuronal assemblies (NAs) is a major challenge in neuroscience. Principal component analysis (PCA) is a widely used method for feature detection, however, when dealing with neuronal data analysis, its limitations have not yet been fully understood. Our work complements previous PCA studies which, in general, characterise NAs based solely on excitatory neuronal interactions. We analysed the performance of PCA in two neglected scenarios: assemblies containing patterns of neural interactions (1) with inhibition and (2) with delays. The analyses considered two types of artificially generated data, one drawn from a traditional Poissonian model, and the other drawn from a latent multivariate Gaussian model; in both models, data from a behaving Wistar rat was used for parameter tuning. Our results highlight scenarios in which neglecting complex interactions between neurons can lead to false conclusions when using PCA to detect NAs. Also, we reinforce the importance of more realistic simulations in the evaluation of neuronal signal processing algorithms.
神经细胞组装(NAs)的解剖和功能表征是神经科学的一个主要挑战。主成分分析(PCA)是一种广泛使用的特征检测方法,但在处理神经元数据分析时,其局限性尚未得到充分认识。我们的工作补充了以前的PCA研究,一般来说,仅仅基于兴奋性神经元相互作用来表征NAs。我们分析了PCA在两种被忽视的情况下的性能:包含(1)抑制和(2)延迟的神经相互作用模式的集合。分析考虑了两种人工生成的数据,一种来自传统的泊松模型,另一种来自潜在的多元高斯模型;在这两个模型中,来自行为Wistar大鼠的数据被用于参数调整。我们的研究结果强调了在使用PCA检测NAs时忽略神经元之间复杂的相互作用可能导致错误结论的情况。此外,我们强调了在评估神经元信号处理算法时更现实的模拟的重要性。
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引用次数: 3
Integrating data and network standards into an interoperable e-Health solution 将数据和网络标准集成到可互操作的电子医疗解决方案中
Carlos Pereira, S. Frade, P. Brandão, R. Correia, Ana Aguiar
E-health has raised a great deal of expectations on improving the quality of health services while simultaneously enabling health services cost reductions. To advance towards those visions, it is imperative to gain the trust of the involved stakeholders, doctors and other medical personnel, patients, families, health care providers and regulators. Even though one critical requirement is interoperability among the various systems involved, currently existing solutions are still vertical silos to a large extent. In this paper, we present an E-health solution that results from the integration of components that comply with rising standards at the various levels of the ICT infrastructure: Machine-to-Machine (M2M) communications for interconnecting devices and services, Health Level 7 (HL7) for communicating with health platforms and openEHR for data semantics, storing and making data available. Concretely, we provide an interoperable and extensible e-health service following these three uprising standards and present the architecture design. We map the service to the various components of the infrastructure building blocks, thus demonstrating how the integration can be successfully accomplished. We are currently developing a prototype solution to be used in a pilot project with 15 elders.
电子保健提高了人们对提高保健服务质量的期望,同时使保健服务能够降低成本。为了实现这些愿景,必须获得相关利益攸关方、医生和其他医务人员、患者、家属、卫生保健提供者和监管机构的信任。尽管一个关键需求是所涉及的各种系统之间的互操作性,但目前现有的解决方案在很大程度上仍然是垂直筒仓。在本文中,我们提出了一种电子医疗解决方案,该解决方案通过集成符合ICT基础设施各个级别不断提高的标准的组件:用于连接设备和服务的机器对机器(M2M)通信,用于与健康平台通信的健康级别7 (HL7),以及用于数据语义、存储和提供数据的openEHR。具体来说,我们按照这三个标准提供了一个可互操作和可扩展的电子医疗服务,并给出了体系结构设计。我们将服务映射到基础设施构建块的各种组件,从而演示如何成功地完成集成。我们目前正在开发一种原型解决方案,将在15位老年人的试点项目中使用。
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引用次数: 12
Knowledge representation for lung cancer patients' prognosis 肺癌患者预后的知识表示
L. Minelli, M. C. d'Ornellas, Ana T. Winck
The gradual increase of cancer cases worldwide has been posing a need on the use of computing resources to accurately retrieve the information recorded in databases. One can highlight the retrieved information importance from a specialist in order to better evaluate pathological response and predict the cancer patient prognosis. This paper presents a way to represent knowledge of cancer registries with emphasis on prognosis. It makes use data mining techniques to find patterns in data stored for patient's lifetime in similar situations. The work is focused on the generation of association rules to find patterns on these registries in order to measure the patient prognosis and drive healthcare experts conclusions. A validation against international oncology organizations and health publications was also made to ensure data and work reliability.
世界范围内癌症病例的逐渐增加,对使用计算资源准确检索数据库中记录的信息提出了要求。为了更好地评估病理反应和预测癌症患者的预后,可以从专家那里突出检索到的信息的重要性。本文提出了一种方法来表示癌症登记处的知识,强调预后。它使用数据挖掘技术在类似情况下的患者生命周期数据中找到模式。这项工作的重点是生成关联规则,以查找这些注册表上的模式,以便衡量患者预后并推动医疗保健专家得出结论。还针对国际肿瘤学组织和卫生出版物进行了验证,以确保数据和工作的可靠性。
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引用次数: 1
期刊
2014 IEEE 16th International Conference on e-Health Networking, Applications and Services (Healthcom)
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