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2014 IEEE 16th International Conference on e-Health Networking, Applications and Services (Healthcom)最新文献

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Limitations of principal component analysis as a method to detect neuronal assemblies 主成分分析作为一种检测神经元集合的方法的局限性
C. S. Deolindo, A. Kunicki, F. Brasil, R. Moioli
The anatomical and functional characterization of neuronal assemblies (NAs) is a major challenge in neuroscience. Principal component analysis (PCA) is a widely used method for feature detection, however, when dealing with neuronal data analysis, its limitations have not yet been fully understood. Our work complements previous PCA studies which, in general, characterise NAs based solely on excitatory neuronal interactions. We analysed the performance of PCA in two neglected scenarios: assemblies containing patterns of neural interactions (1) with inhibition and (2) with delays. The analyses considered two types of artificially generated data, one drawn from a traditional Poissonian model, and the other drawn from a latent multivariate Gaussian model; in both models, data from a behaving Wistar rat was used for parameter tuning. Our results highlight scenarios in which neglecting complex interactions between neurons can lead to false conclusions when using PCA to detect NAs. Also, we reinforce the importance of more realistic simulations in the evaluation of neuronal signal processing algorithms.
神经细胞组装(NAs)的解剖和功能表征是神经科学的一个主要挑战。主成分分析(PCA)是一种广泛使用的特征检测方法,但在处理神经元数据分析时,其局限性尚未得到充分认识。我们的工作补充了以前的PCA研究,一般来说,仅仅基于兴奋性神经元相互作用来表征NAs。我们分析了PCA在两种被忽视的情况下的性能:包含(1)抑制和(2)延迟的神经相互作用模式的集合。分析考虑了两种人工生成的数据,一种来自传统的泊松模型,另一种来自潜在的多元高斯模型;在这两个模型中,来自行为Wistar大鼠的数据被用于参数调整。我们的研究结果强调了在使用PCA检测NAs时忽略神经元之间复杂的相互作用可能导致错误结论的情况。此外,我们强调了在评估神经元信号处理算法时更现实的模拟的重要性。
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引用次数: 3
Integrating data and network standards into an interoperable e-Health solution 将数据和网络标准集成到可互操作的电子医疗解决方案中
Carlos Pereira, S. Frade, P. Brandão, R. Correia, Ana Aguiar
E-health has raised a great deal of expectations on improving the quality of health services while simultaneously enabling health services cost reductions. To advance towards those visions, it is imperative to gain the trust of the involved stakeholders, doctors and other medical personnel, patients, families, health care providers and regulators. Even though one critical requirement is interoperability among the various systems involved, currently existing solutions are still vertical silos to a large extent. In this paper, we present an E-health solution that results from the integration of components that comply with rising standards at the various levels of the ICT infrastructure: Machine-to-Machine (M2M) communications for interconnecting devices and services, Health Level 7 (HL7) for communicating with health platforms and openEHR for data semantics, storing and making data available. Concretely, we provide an interoperable and extensible e-health service following these three uprising standards and present the architecture design. We map the service to the various components of the infrastructure building blocks, thus demonstrating how the integration can be successfully accomplished. We are currently developing a prototype solution to be used in a pilot project with 15 elders.
电子保健提高了人们对提高保健服务质量的期望,同时使保健服务能够降低成本。为了实现这些愿景,必须获得相关利益攸关方、医生和其他医务人员、患者、家属、卫生保健提供者和监管机构的信任。尽管一个关键需求是所涉及的各种系统之间的互操作性,但目前现有的解决方案在很大程度上仍然是垂直筒仓。在本文中,我们提出了一种电子医疗解决方案,该解决方案通过集成符合ICT基础设施各个级别不断提高的标准的组件:用于连接设备和服务的机器对机器(M2M)通信,用于与健康平台通信的健康级别7 (HL7),以及用于数据语义、存储和提供数据的openEHR。具体来说,我们按照这三个标准提供了一个可互操作和可扩展的电子医疗服务,并给出了体系结构设计。我们将服务映射到基础设施构建块的各种组件,从而演示如何成功地完成集成。我们目前正在开发一种原型解决方案,将在15位老年人的试点项目中使用。
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引用次数: 12
A network security architecture to reduce the risk of data leakage for health care organizations 用于降低医疗保健组织数据泄露风险的网络安全架构
R. Rauscher, R. Acharya
Health care is a highly regulated industry in which much value is placed upon privacy and confidentiality. The business of health care, particularly in certain academic environments, requires access to data of varying sensitivities, including information from the public Internet. This paper proposes a VLAN-based architecture for segregating data of varying sensitivities, a list of components that facilitate access to and distillation of data, and a method for one-way promotion of individual nodes from areas of lower security to areas of higher security. The proposed solution is an implementable and pragmatic approach to reducing the risk of data leakage. Quality of experience (QoE) measures of two methods for access (node promotion and porthole-based access) are compared. The node promotion method improves the user-perceived responsiveness of applications over the porthole-based method while reducing flexibility.
医疗保健是一个受到严格监管的行业,非常重视隐私和保密。医疗保健业务,特别是在某些学术环境中,需要获取不同敏感程度的数据,包括来自公共互联网的信息。本文提出了一种基于vlan的架构,用于分离不同敏感性的数据,一种便于访问和提炼数据的组件列表,以及一种将单个节点从低安全性区域单向提升到高安全性区域的方法。建议的解决方案是一种可实现且实用的方法,可减少数据泄漏的风险。比较了两种访问方法(节点提升和基于窗口的访问)的体验质量(QoE)度量。与基于窗口的方法相比,节点提升方法提高了应用程序的用户感知响应性,同时降低了灵活性。
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引用次数: 11
RESTful services for an innovative e-Health infrastructure: A real case study 创新电子卫生基础设施的RESTful服务:一个真实案例研究
F. Vitali, A. Amoroso, M. Roccetti, G. Marfia
We present a REST approach to build Health services on the Web. Our proposal originates by the necessity of evolving the current regional health service to accommodate emerging needs that are too complex to accomplish with the current system. The original system extends on the regional scale of Emilia-Romagna, and it is one of the most advanced in Italy. Our architecture inherits some of the basic Web methodologies and techniques to implement an highly scalable and flexible system that is capable to satisfy the current needs and their planned evolutions. Moreover, our approach should allow for an effortlessly addressing of future requirements not foreseen at the moment. Without revolutionizing the current IT infrastructure, our approach introduces a new paradigm that could be implemented by a sophisticated interface to access data and resources.
我们提出了一种在Web上构建健康服务的REST方法。我们的建议源于发展当前区域卫生服务的必要性,以适应新出现的需求,这些需求过于复杂,无法用现有系统完成。最初的系统在艾米利亚-罗马涅地区范围内扩展,是意大利最先进的系统之一。我们的体系结构继承了一些基本的Web方法和技术,以实现一个高度可伸缩和灵活的系统,该系统能够满足当前的需求及其计划的发展。此外,我们的方法应该允许毫不费力地处理目前无法预见的未来需求。在不改变当前IT基础设施的情况下,我们的方法引入了一种新的范例,可以通过一个复杂的接口来实现访问数据和资源。
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引用次数: 3
QuoTe an extensible platform for QoE monitoring and benchmarking of telemedicine applications 引用一个可扩展的平台,用于远程医疗应用程序的QoE监控和基准测试
M. Varela, Toni Mäki, J. Merilahti, E. R. Rodriguez, A. Runge
Telemedicine applications provide many opportunities for improving health care in a variety of conditions, in particular for people living in remote or geographically isolated areas without fast access to doctors (“medical deserts”), such as some parts of Finland. In many applications, the technologies used are actually off-the shelf solutions for videoconferencing, in some cases even used in an Over The Top (OTT) fashion over best-effort networks. In these contexts, the quality (both Quality of Experience and Quality of Service) of the whole system can have a greater significance than in other contexts such as entertainment, yet there are no quality monitoring and assessment systems specifically conceived for this purpose. In this paper we present an on-going effort to develop an extensible quality monitoring and benchmarking platform designed with video-based telemedicine applications, and the particular issues associated with them, in mind.
远程医疗的应用为改善各种条件下的卫生保健提供了许多机会,特别是对于生活在偏远或地理上孤立、无法快速就医的地区("医疗沙漠")的人们,例如芬兰的一些地区。在许多应用程序中,所使用的技术实际上是现成的视频会议解决方案,在某些情况下,甚至在尽力而为的网络上以Over the Top (OTT)方式使用。在这些环境中,整个系统的质量(体验质量和服务质量)可能比其他环境(如娱乐)更重要,但没有专门为此目的设想的质量监控和评估系统。在本文中,我们提出了一项正在进行的努力,以开发一个可扩展的质量监测和基准测试平台,该平台设计基于视频的远程医疗应用,以及与之相关的特定问题。
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引用次数: 3
Color energy as a seed descriptor for image segmentation with region growing algorithms on skin wound images 颜色能量作为种子描述符用于皮肤伤口图像的区域生长分割
J. L. Seixas, Sylvio Barbon Junior, C. Siqueira, I. Dias, Andre Giovanni Castaldin, A. S. Felinto
This paper presents a seed finding method for region growing segmentation approach using color channel energy in image regions. Instead of using the RGB system separated for each pixel, the proposal uses the energy on each color channel to improve the range of the possible values, then creates a more specific seed to detail different regions. Region size used to calculate energy was adjusted to verify the proposed method. Images used were real wound photos, taken from patients undergoing treatment at the university hospital. Results showed that energy on regions presents enough information to segment, leading to a high percentage of matching with experts marks.
提出了一种利用图像区域颜色通道能量进行区域增长分割的种子寻找方法。该方案不是使用RGB系统对每个像素进行分离,而是使用每个颜色通道上的能量来提高可能值的范围,然后创建一个更具体的种子来详细描述不同的区域。通过调整用于计算能量的区域大小来验证所提出的方法。使用的图像是在大学医院接受治疗的患者的真实伤口照片。结果表明,区域上的能量提供了足够的信息进行分割,与专家标记的匹配率很高。
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引用次数: 11
A global methodology for modeling and simulating medical systems 建模和模拟医疗系统的全球方法
C. El-Gemayel, F. Jumel, N. Abouchi, J. Constantin, Doumit Zaouk
A mathematical representation of patient or device is presented by a number of variables which are defined to represent the inputs, outputs and a set of equations describing the interaction of these variables. This paper proposes a global methodology for modeling and simulation medical systems and human body, in order to analyze the performance and the quality of services of all system components. Beginning by defining a new prototype of a global and flexible architecture of mathematical model of human body, that is able to contain required data. Then, describing the simulations representation, by mentions in details the core simulator components, analyzer, and the quality of services indicators. Simulation of mathematical models provides useful tools for diagnosis and analyzing the interactions between efficacy, therapies, side-effects, and outcomes. This will help to better understand the human organism control, to analyze experimental data, to identify and quantify relevant biophysical parameters and to design clinical trials.
病人或设备的数学表示是由许多变量来表示的,这些变量被定义为表示输入、输出和一组描述这些变量相互作用的方程。本文提出了一种对医疗系统和人体进行建模和仿真的全局方法,以分析系统各组成部分的性能和服务质量。首先定义一个新的原型,一个全球性的和灵活的人体数学模型的架构,能够包含所需的数据。然后,通过详细介绍模拟器的核心组件、分析器和服务质量指标,描述了仿真的表示。数学模型的模拟为诊断和分析疗效、治疗、副作用和结果之间的相互作用提供了有用的工具。这将有助于更好地理解人体有机体控制,分析实验数据,识别和量化相关的生物物理参数,并设计临床试验。
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引用次数: 0
Health sensing by wearable sensors and mobile phones: A survey 可穿戴式传感器和移动电话的健康感知:一项调查
Lei Song, Yongcai Wang, Jijiang Yang, Jianqiang Li
With the global trend of population aging in industrialized countries, efficient information and communication technologies (ICT) for aiding elders or patients' healthcare have attracted great research attentions. Among these technologies, health state sensing by wearable sensors and mobile phones is an important foundation. It monitors the real-time body states; stores, or sends the result to remote family members or doctors. In this way, it can either help people to pay more attention to the overlooked phenomenon, such as the clue of dangerous disease, or help people to issue panic alert when emergency happens. There are many critical issues in health sensing. First, the sensors must be non-intrusive to people's comfort and safety, while providing good accuracy. At the same time, because of being worn by people, numerous noises posed by body motions must be efficiently processed for reducing false alarming. At last, different health or decease signals generally require different sensing technologies and instrument. To tease out the technology advantages that address these challenges and diversities, this paper presented a survey on the state of the art of health sensing technologies using body sensor networks and mobile phones. It classify related works by their application goals, including i) fall detection, ii) gait analyzing, iii) activity qualification, iv) heart state sensing, and v) sleep sensing. It also conducts summary and comparison of related sensing systems and algorithms, to reveal the development lines in each subarea.
随着全球人口老龄化的趋势在工业化国家,有效信息和通讯技术(ICT)帮助老人或病人的医疗吸引了巨大的研究关注。在这些技术中,健康状态感知的可穿戴传感器和移动电话是一个重要的基础。它监视实时身体状态;储存,或将结果发送给远程家庭成员或医生。这样,它既可以帮助人们更加关注被忽视的现象,如危险疾病的线索,也可以帮助人们在紧急情况发生时发出恐慌警报。有许多关键问题医疗传感。首先,传感器必须不影响人们的舒适和安全,同时提供良好的准确性。同时,因为被人穿的,大量的噪音造成的身体动作必须有效地减少虚假报警处理。最后,不同的健康或者死亡信号通常需要不同的传感技术和仪器。梳理出技术优势,解决这些挑战和多样性,本文提出了一个艺术的健康状况调查传感技术使用身体传感器网络和手机。它分类相关的应用程序的目标,包括我)检测,2)步态分析、iii)活动资格,(四)心脏状态传感和传感v)睡觉。它也进行总结和比较相关的传感系统和算法,揭示了在每个分区开发线。
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引用次数: 29
Security aspects of e-Health systems migration to the cloud 电子医疗系统向云迁移的安全方面
A. Michalas, Nicolae Paladi, C. Gehrmann
As adoption of e-health solutions advances, new computing paradigms - such as cloud computing - bring the potential to improve efficiency in managing medical health records and help reduce costs. However, these opportunities introduce new security risks which can not be ignored. Based on our experience with deploying part of the Swedish electronic health records management system in an infrastructure cloud, we make an overview of major requirements that must be considered when migrating e-health systems to the cloud. Furthermore, we describe in-depth a new attack vector inherent to cloud deployments and present a novel data confidentiality and integrity protection mechanism for infrastructure clouds. This contribution aims to encourage exchange of best practices and lessons learned in migrating public e-health systems to the cloud.
随着采用电子保健解决方案的进展,新的计算范式(如云计算)带来了提高医疗健康记录管理效率和帮助降低成本的潜力。然而,这些机会也带来了不可忽视的新的安全风险。根据我们在基础设施云中部署部分瑞典电子健康记录管理系统的经验,我们概述了将电子健康系统迁移到云时必须考虑的主要需求。此外,我们深入描述了云部署固有的新攻击向量,并提出了一种新的基础设施云数据机密性和完整性保护机制。这项贡献旨在鼓励交流将公共电子卫生系统迁移到云的最佳做法和经验教训。
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引用次数: 40
Using Bayesian networks to improve the decision-making process in public health systems 利用贝叶斯网络改进公共卫生系统的决策过程
Germanno Teles, C. Oliveira, R. Braga, L. O. M. Andrade, Ronaldo F. Ramos, Paulo Cunha, Mauro Oliveira
This paper proposes the use of Bayesian networks to support the decision-making process in public health systems. In particular, this paper presents LARIISA_Bay, a new component based on Bayesian networks that works together with LARIISA, a context-aware platform to support applications in public health systems. The main goal of the proposed component is to assist teams of health specialists in order to better diagnose diseases through data collected from users of LARIISA. As a case study, we focus on scenarios of dengue fever disease. We classify dengue cases into one of the following levels: normal, grave or emergency. Based on this classification, teams of health specialists can accurately make decisions, for example, to alert a health care agent to visit locations with a high incidence of the disease, to send a team of health specialists when a dengue emergency case has occurred, as well as give technical instructions on how to deal with specific cases. We present a prototype of LARIISA_Bay as well as the corresponding interfaces to support the interactions with the component. We compare the obtained results with real diagnosis of general practitioners. The results presented show the efficiency of the proposed approach.
本文提出使用贝叶斯网络来支持公共卫生系统的决策过程。特别地,本文介绍了LARIISA_Bay,这是一个基于贝叶斯网络的新组件,它与LARIISA一起工作,LARIISA是一个支持公共卫生系统应用的上下文感知平台。拟议组成部分的主要目标是协助保健专家小组,以便通过从LARIISA用户收集的数据更好地诊断疾病。作为一个案例研究,我们侧重于登革热疾病的情景。我们将登革热病例分为以下级别之一:正常、严重或紧急情况。根据这种分类,卫生专家小组可以准确地作出决定,例如,提醒卫生保健人员前往疾病高发地点,在发生登革热紧急病例时派遣卫生专家小组,以及就如何处理具体病例提供技术指导。我们提出了LARIISA_Bay的原型,以及相应的接口来支持与组件的交互。我们将所得结果与全科医生的真实诊断结果进行比较。实验结果表明了该方法的有效性。
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引用次数: 4
期刊
2014 IEEE 16th International Conference on e-Health Networking, Applications and Services (Healthcom)
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