Pub Date : 2022-05-25DOI: 10.51435/turkjac.1104578
Cemalettin Baltacı, Muhammed Şi̇di̇m, Zeynep Akşit
{"title":"Effects of spray and freeze-drying methods on aroma compounds, sensory characteristics, physicochemical composition, antioxidant and antimicrobial properties of instant sage (Salvia rosifolia Sm.) tea","authors":"Cemalettin Baltacı, Muhammed Şi̇di̇m, Zeynep Akşit","doi":"10.51435/turkjac.1104578","DOIUrl":"https://doi.org/10.51435/turkjac.1104578","url":null,"abstract":"","PeriodicalId":274781,"journal":{"name":"Turkish Journal of Analytical Chemistry","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130052596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-21DOI: 10.51435/turkjac.1111456
Hasan Kaçar, S. Yilmaz, Muhammet Türkoğlu, M. Sadıkoğlu
{"title":"Seasonal variations in tap water quality parameters in Canakkale, Turkey","authors":"Hasan Kaçar, S. Yilmaz, Muhammet Türkoğlu, M. Sadıkoğlu","doi":"10.51435/turkjac.1111456","DOIUrl":"https://doi.org/10.51435/turkjac.1111456","url":null,"abstract":"","PeriodicalId":274781,"journal":{"name":"Turkish Journal of Analytical Chemistry","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132166078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-06DOI: 10.51435/turkjac.1069294
A. Nosal-Wiercińska, M. Martyna, M. Wiśniewska, S. Yilmaz, Nuray Denizhan
{"title":"Application of a cyclic renewable silver amalgam liquid film electrode (R-AgLAFE) to study the electroreduction processes of Bi(III) ions in the presence of cysteine","authors":"A. Nosal-Wiercińska, M. Martyna, M. Wiśniewska, S. Yilmaz, Nuray Denizhan","doi":"10.51435/turkjac.1069294","DOIUrl":"https://doi.org/10.51435/turkjac.1069294","url":null,"abstract":"","PeriodicalId":274781,"journal":{"name":"Turkish Journal of Analytical Chemistry","volume":"318 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115437665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Safa M. Megahed, Ahmed A. Habib, Sherin F Hammad, Amira H. Kamal
{"title":"Chemometric Approach Based on Factorial and Box-Behnken Designs for Determination of Anti Coronavirus Drug; Favipiravir in Bulk and Spiked Human Plasma by Green HPLC Method","authors":"Safa M. Megahed, Ahmed A. Habib, Sherin F Hammad, Amira H. Kamal","doi":"10.51435/turkjac.963652","DOIUrl":"https://doi.org/10.51435/turkjac.963652","url":null,"abstract":"","PeriodicalId":274781,"journal":{"name":"Turkish Journal of Analytical Chemistry","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115511661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-26DOI: 10.51435/turkjac.1032908
F. Akdeniz, İnan Dursun, Kadir Tepebaş, H. Özbay, Levent Kekec, Samet Yildiz
{"title":"Comparison of the extracts obtained from dried Diospyros lotus L. fruits via different extraction techniques in terms of their total phenolic contents and antioxidant activities","authors":"F. Akdeniz, İnan Dursun, Kadir Tepebaş, H. Özbay, Levent Kekec, Samet Yildiz","doi":"10.51435/turkjac.1032908","DOIUrl":"https://doi.org/10.51435/turkjac.1032908","url":null,"abstract":"","PeriodicalId":274781,"journal":{"name":"Turkish Journal of Analytical Chemistry","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127881146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-17DOI: 10.51435/turkjac.1030232
Abidin GÜmrÜkÇÜoĞlu, O. Bekircan
{"title":"Synthesis and analytical applications of thiosemicarbazide derivatives","authors":"Abidin GÜmrÜkÇÜoĞlu, O. Bekircan","doi":"10.51435/turkjac.1030232","DOIUrl":"https://doi.org/10.51435/turkjac.1030232","url":null,"abstract":"","PeriodicalId":274781,"journal":{"name":"Turkish Journal of Analytical Chemistry","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125039040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Non-Aqueous medium titrations of some 3-alkyl(aryl)-4-[3-(2-metylbenzoxy)-4-methoxybenzylideneamino]-4,5-dihydro-1H-1,2,4-triazol-5-ones","authors":"H. Yüksek, Osman Kutani̇s, S. Manap, G. Özdemir","doi":"10.51435/turkjac.940812","DOIUrl":"https://doi.org/10.51435/turkjac.940812","url":null,"abstract":"","PeriodicalId":274781,"journal":{"name":"Turkish Journal of Analytical Chemistry","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127353257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Investigation of acidic properties of 2-ethoxy-6-(3-substitue-4,5-dihydro-1H-1,2,4-triazol-5-one-4-yl-azomethine)-phenyl benzoates","authors":"H. Yüksek, Faruk Kardaş, S. Manap, G. Özdemir","doi":"10.51435/turkjac.940613","DOIUrl":"https://doi.org/10.51435/turkjac.940613","url":null,"abstract":"","PeriodicalId":274781,"journal":{"name":"Turkish Journal of Analytical Chemistry","volume":"160 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133573160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cancer is one of the major diseases affecting all humanity with high mortality rates worldwide. Its treatment is difficult, long-term and expensive. Due to its side effects, it is troublesome for both the patient and their attendants. Cancer treatment is basically divided into three: surgery, chemotherapy and radiotherapy. Photodynamic therapy offers one of the most important and promising treatment methods, especially in recent years. Photodynamic therapy takes the steps of administering the photo-sensitizing compound to the body and stimulating it with a light of appropriate wavelength after its accumulation in the target tissue. With the formation of complex processes that take place in the target area with the reactive oxygen species formed by the stimulated compounds, death or the inhibition of the proliferation of the cells causes situations such as the destruction of the target tissue. Phthalocyanines constitute an important group of photo-sensitizers used in photodynamic therapy. Stability of these compounds and their strong absorption close to therapeutic window make these compounds important. With large Π systems, they can bind with many biological macromolecules, including DNA, with high affinity by many mechanisms, including the Π - Π stacking. This review article describes the last three years of studies in the WOS database about the interactions of phthalocyanines with DNA. The interactions of phthalocyanines with DNA are important as they can make a difference in the proliferation of tumor cells. On the other hand, DNA replication and transcription has increased due to the increasing metabolic rate of these cells. The DNA double strand opened during replication, and gene expression allows the formation of different secondary structures such as hairpin, triple, junctions, and G-quadruplex. The interaction of G-quadruplex DNA structures with these compounds, which can be formed in the guanine-rich regions of the DNA sequences opened in these processes, has been described in studies.
{"title":"The recent studies about the interaction of phthalocyanine with DNA","authors":"E. Bağda, Efkan Bağda","doi":"10.51435/turkjac.938781","DOIUrl":"https://doi.org/10.51435/turkjac.938781","url":null,"abstract":"Cancer is one of the major diseases affecting all humanity with high mortality rates worldwide. Its treatment is difficult, long-term and expensive. Due to its side effects, it is troublesome for both the patient and their attendants. Cancer treatment is basically divided into three: surgery, chemotherapy and radiotherapy. Photodynamic therapy offers one of the most important and promising treatment methods, especially in recent years. Photodynamic therapy takes the steps of administering the photo-sensitizing compound to the body and stimulating it with a light of appropriate wavelength after its accumulation in the target tissue. With the formation of complex processes that take place in the target area with the reactive oxygen species formed by the stimulated compounds, death or the inhibition of the proliferation of the cells causes situations such as the destruction of the target tissue. Phthalocyanines constitute an important group of photo-sensitizers used in photodynamic therapy. Stability of these compounds and their strong absorption close to therapeutic window make these compounds important. With large Π systems, they can bind with many biological macromolecules, including DNA, with high affinity by many mechanisms, including the Π - Π stacking. This review article describes the last three years of studies in the WOS database about the interactions of phthalocyanines with DNA. The interactions of phthalocyanines with DNA are important as they can make a difference in the proliferation of tumor cells. On the other hand, DNA replication and transcription has increased due to the increasing metabolic rate of these cells. The DNA double strand opened during replication, and gene expression allows the formation of different secondary structures such as hairpin, triple, junctions, and G-quadruplex. The interaction of G-quadruplex DNA structures with these compounds, which can be formed in the guanine-rich regions of the DNA sequences opened in these processes, has been described in studies.","PeriodicalId":274781,"journal":{"name":"Turkish Journal of Analytical Chemistry","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125582215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Currently, there are no specific drugs for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, designated as coronavirus disease 2019 (COVID-19). Several therapeutic options including antiviral, antithrombotic, immunosuppressive, and anti-rheumatic drugs are researched all over the world. Analytical methods are needed in every step of innovation, research, development, and manufacturing process of pharmaceuticals, therefore new analytical methods for pharmaceuticals are developed and validated increasingly over time. In this review, recent reports on electroanalytical techniques for the determination of selected COVID-19 drugs, favipiravir (FAV), remdesivir (REM), lopinavir (LOP) / ritonavir (RIT), and hydroxychloroquine (HCQ) were emphasized. Electroanalysis of antiviral active pharmaceutical ingredients carried out at various modified or non-modified electrodes by cyclic voltammetry (CV), linear sweep voltammetry (LSV), differential pulse voltammetry (DPV), and square wave voltammetry (SWV) were compiled from the literature. The effects of supporting electrolyte and pH on the current and potential of the analytical signal were evaluated. Scan rate results obtained by the CV method showed whether the redox process of the drug active ingredient diffusion or adsorption controlled at the electrode used in the selected solvent-supporting electrolyte and pH systems. Linearity range and the limit of detection (LOD) of applied electroanalytical methods were compared by combining the results obtained from drug active ingredients given in references.
{"title":"A review on recent electroanalytical methods for the analysis of COVID-19 drugs","authors":"D. Emre, N. Özaltın, S. Yilmaz","doi":"10.51435/turkjac.935765","DOIUrl":"https://doi.org/10.51435/turkjac.935765","url":null,"abstract":"Currently, there are no specific drugs for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, designated as coronavirus disease 2019 (COVID-19). Several therapeutic options including antiviral, antithrombotic, immunosuppressive, and anti-rheumatic drugs are researched all over the world. Analytical methods are needed in every step of innovation, research, development, and manufacturing process of pharmaceuticals, therefore new analytical methods for pharmaceuticals are developed and validated increasingly over time. In this review, recent reports on electroanalytical techniques for the determination of selected COVID-19 drugs, favipiravir (FAV), remdesivir (REM), lopinavir (LOP) / ritonavir (RIT), and hydroxychloroquine (HCQ) were emphasized. Electroanalysis of antiviral active pharmaceutical ingredients carried out at various modified or non-modified electrodes by cyclic voltammetry (CV), linear sweep voltammetry (LSV), differential pulse voltammetry (DPV), and square wave voltammetry (SWV) were compiled from the literature. The effects of supporting electrolyte and pH on the current and potential of the analytical signal were evaluated. Scan rate results obtained by the CV method showed whether the redox process of the drug active ingredient diffusion or adsorption controlled at the electrode used in the selected solvent-supporting electrolyte and pH systems. Linearity range and the limit of detection (LOD) of applied electroanalytical methods were compared by combining the results obtained from drug active ingredients given in references.","PeriodicalId":274781,"journal":{"name":"Turkish Journal of Analytical Chemistry","volume":"385 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123353493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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