Chemistry, 61080 Trabzon, Turkey Abstract The synthesis of novel phthalonitrile ( 3 ) and synthesis, spectroscopic and electrochemical properties of the following octa-benzothiazole substituted metal-free ( 4 ), cobalt(II) ( 5 ), and zinc(II) ( 6 ) phthalocyanines are reported for the first time in this work. The novel phthalonitrile ( 3 ) has been characterized by FT-IR, 1 H NMR, 13 C NMR, and mass spectroscopy and the novel phthalocyanines ( 4-6 ) have been characterized by FT-IR, electronic spectroscopy, and mass spectroscopy. Voltammetric analysis of benzothiazole group substituted phthalocyanines (MPc) were determined by cyclic voltammetry (CV) and square wave voltammetry (SWV). According to the results, phthalocyanines revealed metal and ligand-based quasi-reversible reduction and oxidation processes. While the CoPc 5 showed one metal-based and one Pc-based reduction reactions, H 2 Pc 4 and ZnPc 6 gave
{"title":"New Octa-Benzothiazole Substituted Metal Free and Metallophthalocyanines: Synthesis, Characterization and Electrochemical Studies","authors":"Gülsev Di̇lber, A. Nas, Z. Bıyıklıoğlu","doi":"10.51435/turkjac.935057","DOIUrl":"https://doi.org/10.51435/turkjac.935057","url":null,"abstract":"Chemistry, 61080 Trabzon, Turkey Abstract The synthesis of novel phthalonitrile ( 3 ) and synthesis, spectroscopic and electrochemical properties of the following octa-benzothiazole substituted metal-free ( 4 ), cobalt(II) ( 5 ), and zinc(II) ( 6 ) phthalocyanines are reported for the first time in this work. The novel phthalonitrile ( 3 ) has been characterized by FT-IR, 1 H NMR, 13 C NMR, and mass spectroscopy and the novel phthalocyanines ( 4-6 ) have been characterized by FT-IR, electronic spectroscopy, and mass spectroscopy. Voltammetric analysis of benzothiazole group substituted phthalocyanines (MPc) were determined by cyclic voltammetry (CV) and square wave voltammetry (SWV). According to the results, phthalocyanines revealed metal and ligand-based quasi-reversible reduction and oxidation processes. While the CoPc 5 showed one metal-based and one Pc-based reduction reactions, H 2 Pc 4 and ZnPc 6 gave","PeriodicalId":274781,"journal":{"name":"Turkish Journal of Analytical Chemistry","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124898803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The acidic properties of ten 3-alkyl(aryl)-4-[3-hydroxy-4-methoxy benzylidenamino]-4,5-dihydro-1H-1,2,4-triazol-5-one derivatives were investigated. In this study, isopropyl alcohol and tert‐butanol were used as an amphiprotic solvent. Aceton and N,N‐ dimethylformamide (DMF) were preferred as a dipolar aprotic solvent. Compounds were titrated with tetrabuthylamonnium hydroxide (TBAH) in isopropyl alcohol and titrimetric analyses were used potentiometric method determining the end-points, half-neutralization method determining acidity. Typical S-shaped titration graphs excepted were determined. The acidity strengths of 4,5-dihydro-1H-1,2,4-triazol-5-one derivatives in amphiprotic and dipolar aprotic solvents were calculated using tables and graphs. The pKa values obtained in the solvents were found to be differentiated. The effects of solvent, molecular structure, autoprotolysis constant dielectric constant, and leveling‐differentiation effects of the solvents upon acidity strength of the compounds were discussed.
{"title":"Solvent and moleculer structure effects on acidity strength in non-aqueous medium","authors":"Ş. Bahçeci, Zafer Ocak, N. Yildirim, H. Yüksek","doi":"10.51435/turkjac.939857","DOIUrl":"https://doi.org/10.51435/turkjac.939857","url":null,"abstract":"The acidic properties of ten 3-alkyl(aryl)-4-[3-hydroxy-4-methoxy benzylidenamino]-4,5-dihydro-1H-1,2,4-triazol-5-one derivatives were investigated. In this study, isopropyl alcohol and tert‐butanol were used as an amphiprotic solvent. Aceton and N,N‐ dimethylformamide (DMF) were preferred as a dipolar aprotic solvent. Compounds were titrated with tetrabuthylamonnium hydroxide (TBAH) in isopropyl alcohol and titrimetric analyses were used potentiometric method determining the end-points, half-neutralization method determining acidity. Typical S-shaped titration graphs excepted were determined. The acidity strengths of 4,5-dihydro-1H-1,2,4-triazol-5-one derivatives in amphiprotic and dipolar aprotic solvents were calculated using tables and graphs. The pKa values obtained in the solvents were found to be differentiated. The effects of solvent, molecular structure, autoprotolysis constant dielectric constant, and leveling‐differentiation effects of the solvents upon acidity strength of the compounds were discussed.","PeriodicalId":274781,"journal":{"name":"Turkish Journal of Analytical Chemistry","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115540506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Three Verbascum Plants from North West Anatolia (Turkey) as a Source of Biological Activities","authors":"N. Hacıoğlu, N. Demir, Ö. Yilmaz","doi":"10.51435/turkjac.886692","DOIUrl":"https://doi.org/10.51435/turkjac.886692","url":null,"abstract":"","PeriodicalId":274781,"journal":{"name":"Turkish Journal of Analytical Chemistry","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121355566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gozde Kılıç, B. Korkmaz, İ. Erİk, S. Fandaklı, Sevde Seher Yaylı, Özlem Faiz, Şengül Alpay Karaoğlu, N. Yaylı
{"title":"Antimicrobial, antioxidant, tyrosinase activities and volatile compounds of the Essential oil and Solvent Extract of Epilobium hirsutum L. growing in Turkey","authors":"Gozde Kılıç, B. Korkmaz, İ. Erİk, S. Fandaklı, Sevde Seher Yaylı, Özlem Faiz, Şengül Alpay Karaoğlu, N. Yaylı","doi":"10.51435/turkjac.813224","DOIUrl":"https://doi.org/10.51435/turkjac.813224","url":null,"abstract":"","PeriodicalId":274781,"journal":{"name":"Turkish Journal of Analytical Chemistry","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127179029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Synthesis and aggregation properties of 2,9,16,23–tetrakis(chloro)-3,10,17,24–tetrakis[2-(4-allyl-2methoxyphenoxy)ethoxy]phthalocyaninato cobalt(II), manganese(III), zinc(II)","authors":"Gülpınar Sarkı, Halise Yalazan, H. Kantekin","doi":"10.51435/turkjac.813227","DOIUrl":"https://doi.org/10.51435/turkjac.813227","url":null,"abstract":"","PeriodicalId":274781,"journal":{"name":"Turkish Journal of Analytical Chemistry","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126725421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"One pot synthesis and spectral characterization of 5-Substitutedfuran-2-carbaldehyde N4-cyclohexyl thiosemicarbazones and their Ni(II) complexes","authors":"A. Iyidoğan, E. E. Oruç-Emre, Ülkü Çakır","doi":"10.51435/turkjac.813792","DOIUrl":"https://doi.org/10.51435/turkjac.813792","url":null,"abstract":"","PeriodicalId":274781,"journal":{"name":"Turkish Journal of Analytical Chemistry","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134544002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This work presents the synthesis of four phthalonitrile compounds (3 a-d ) bearing different chalcone moiety which have biological activities. Phthalonitrile compounds are a considerable pioneer in the synthesis of novel photoactive phthalocyanine derivatives. Antioxidant activity of the new phthalonitrile compounds (3 a and 3 b ) and those of one’s synthesized previously (3 c and 3 d ) have been studied after the determination of their spectroscopic properties. Ferric reducing/antioxidant power (FRAP) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) methods have been used to determine the antioxidant activities of the compounds. According to the DPPH radical scavenging activity values, the antioxidant activity of 4-{3-[(2E)-3-(4-nitrophenyl)prop-2-enoyl]phenoxy}phthalonitrile 3 b is significantly higher than the counterparts.
{"title":"Antioxidant activity of phthalonitrile derivatives bearing different chalcone groups","authors":"Ayşe Aktaş Kamiloğlu, Z. Can, Gonca Çelik","doi":"10.51435/turkjac.806398","DOIUrl":"https://doi.org/10.51435/turkjac.806398","url":null,"abstract":"This work presents the synthesis of four phthalonitrile compounds (3 a-d ) bearing different chalcone moiety which have biological activities. Phthalonitrile compounds are a considerable pioneer in the synthesis of novel photoactive phthalocyanine derivatives. Antioxidant activity of the new phthalonitrile compounds (3 a and 3 b ) and those of one’s synthesized previously (3 c and 3 d ) have been studied after the determination of their spectroscopic properties. Ferric reducing/antioxidant power (FRAP) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) methods have been used to determine the antioxidant activities of the compounds. According to the DPPH radical scavenging activity values, the antioxidant activity of 4-{3-[(2E)-3-(4-nitrophenyl)prop-2-enoyl]phenoxy}phthalonitrile 3 b is significantly higher than the counterparts.","PeriodicalId":274781,"journal":{"name":"Turkish Journal of Analytical Chemistry","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134098010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anacyclus pyrethrum (L.) Lag. is an herb that fits into the Asteraceae family. It has been using to treat several disorders include lung infections, liver diseases, nervous system diseases, and rheumatism in ethnomedicines. Compounds including pellitorine, anacycline, spilanthol, pyracyclumine A, and agrocybenine have been isolated from this plant species. Thus, this overview work intends to scrutinize, sum up, and record the available bioactive scientific evidence of A. pyrethrum. This work would be very convenient for future bioactivity and phytochemical studies of this plant species. Electronic databases such as the Web of Science, Scopus, ScienceDirect, and PubMed were applied to identify appropriate published articles associated with bioactivities of A. pyrethrum from 1900 to November 2020. Until now, all three levels (clinical, in vivo, and in vitro) of bioactive scientific evidence are existing for various parts of this plant species. Bioactivities including anesthetic, antidepressant, antiepileptic, blood circulatory, and anticonvulsive activities in diverse assays and models. Seven antiprotozoal active compounds and an anti-inflammatory active compound have been identified in A. pyrethrum. More bioactivities and phytochemical linked researches should be conducted to generate more scientific evidence for the ethnomedicinal uses. This work scrutinized, summed up, and recorded the currently available bioactive scientific evidence of A. pyrethrum.
除虫菊无环虫滞后。是一种属于菊科的草本植物。它已被用于治疗几种疾病，包括肺部感染，肝脏疾病，神经系统疾病和风湿病的民族医学。从该植物中分离出了pellitorine、anacycle、spilanthol、pyraccycline A和agrocybenine等化合物。因此，本综述工作旨在仔细审查，总结和记录现有的除虫菊生物活性的科学证据。本研究为该植物的生物活性和植物化学研究提供了便利。应用Web of Science、Scopus、ScienceDirect和PubMed等电子数据库识别1900年至2020年11月期间与除虫菊生物活性相关的适当发表文章。到目前为止，所有三个层次(临床，体内和体外)的生物活性科学证据都存在于该植物的各个部分。生物活性包括麻醉，抗抑郁，抗癫痫，血液循环和抗惊厥活动在不同的分析和模型。从除虫菊中鉴定出7种抗原虫活性化合物和1种抗炎活性化合物。应开展更多的生物活性和植物化学相关研究，为其民族医学用途提供更多的科学证据。这项工作仔细审查，总结，并记录了目前可获得的除虫菊的生物活性科学证据。
{"title":"Bioactivities of Anacyclus pyrethrum (L.) Lag. extracts and natural products","authors":"S. Sathasivampillai, Sujarajini Varatharasan","doi":"10.51435/turkjac.830501","DOIUrl":"https://doi.org/10.51435/turkjac.830501","url":null,"abstract":"Anacyclus pyrethrum (L.) Lag. is an herb that fits into the Asteraceae family. It has been using to treat several disorders include lung infections, liver diseases, nervous system diseases, and rheumatism in ethnomedicines. Compounds including pellitorine, anacycline, spilanthol, pyracyclumine A, and agrocybenine have been isolated from this plant species. Thus, this overview work intends to scrutinize, sum up, and record the available bioactive scientific evidence of A. pyrethrum. This work would be very convenient for future bioactivity and phytochemical studies of this plant species. Electronic databases such as the Web of Science, Scopus, ScienceDirect, and PubMed were applied to identify appropriate published articles associated with bioactivities of A. pyrethrum from 1900 to November 2020. Until now, all three levels (clinical, in vivo, and in vitro) of bioactive scientific evidence are existing for various parts of this plant species. Bioactivities including anesthetic, antidepressant, antiepileptic, blood circulatory, and anticonvulsive activities in diverse assays and models. Seven antiprotozoal active compounds and an anti-inflammatory active compound have been identified in A. pyrethrum. More bioactivities and phytochemical linked researches should be conducted to generate more scientific evidence for the ethnomedicinal uses. This work scrutinized, summed up, and recorded the currently available bioactive scientific evidence of A. pyrethrum.","PeriodicalId":274781,"journal":{"name":"Turkish Journal of Analytical Chemistry","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126000105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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