Pub Date : 2019-11-26DOI: 10.1201/9780429316944-28
Joseph D. Love
Introduction: Colonic volvulus is a rare entity associated with high mortality rates. Most studies come from areas of high endemicity and are limited by small numbers. No studies have investigated trends, outcomes, and predictors of mortality at the national level. Methods : The Nationwide Inpatient Sample 2002–2010 was retrospectively reviewed for colonic volvulus cases admitted emergently. Patients’ demographics, hospital factors, and outcomes of the different procedures were analyzed. The LASSO algorithm for logistic regression was used to build a predictive model for mortality in cases of sigmoid (SV) and cecal volvulus (CV) taking into account preoperative and operative variables. Results: An estimated 3,351,152 cases of bowel obstruction were admitted in the United States over the study period. Colonic volvulus was found to be the cause in 63,749 cases (1.90%). The incidence of CV increased by 5.53% per year whereas the incidence of SV remained stable. SV was more common in elderly males (aged 70 years), African Americans, and patients with diabetes and neuropsychiatric disorders. In contrast, CV was more common in younger females. Nonsurgical decompression alone was used in 17% of cases. Among cases managed surgically, resective procedures were performed in 89% of cases, whereas operative detorsion with or without fixation procedures remained uncommon. Mortality rates were 9.44% for SV, 6.64% for CV, 17% for synchronous CV and SV, and 18% for transverse colon volvulus. The LASSO algorithm identified bowel gangrene and peritonitis, coagulopathy, age, the use of stoma, and chronic kidney disease as strong predictors of mortality. Conclusions: Colonic volvulus is a rare cause of bowel obstruction in the
{"title":"Colonic Volvulus in the United States: Trends, Outcomes, and Predictors of Mortality","authors":"Joseph D. Love","doi":"10.1201/9780429316944-28","DOIUrl":"https://doi.org/10.1201/9780429316944-28","url":null,"abstract":"Introduction: Colonic volvulus is a rare entity associated with high mortality rates. Most studies come from areas of high endemicity and are limited by small numbers. No studies have investigated trends, outcomes, and predictors of mortality at the national level. Methods : The Nationwide Inpatient Sample 2002–2010 was retrospectively reviewed for colonic volvulus cases admitted emergently. Patients’ demographics, hospital factors, and outcomes of the different procedures were analyzed. The LASSO algorithm for logistic regression was used to build a predictive model for mortality in cases of sigmoid (SV) and cecal volvulus (CV) taking into account preoperative and operative variables. Results: An estimated 3,351,152 cases of bowel obstruction were admitted in the United States over the study period. Colonic volvulus was found to be the cause in 63,749 cases (1.90%). The incidence of CV increased by 5.53% per year whereas the incidence of SV remained stable. SV was more common in elderly males (aged 70 years), African Americans, and patients with diabetes and neuropsychiatric disorders. In contrast, CV was more common in younger females. Nonsurgical decompression alone was used in 17% of cases. Among cases managed surgically, resective procedures were performed in 89% of cases, whereas operative detorsion with or without fixation procedures remained uncommon. Mortality rates were 9.44% for SV, 6.64% for CV, 17% for synchronous CV and SV, and 18% for transverse colon volvulus. The LASSO algorithm identified bowel gangrene and peritonitis, coagulopathy, age, the use of stoma, and chronic kidney disease as strong predictors of mortality. Conclusions: Colonic volvulus is a rare cause of bowel obstruction in the","PeriodicalId":282445,"journal":{"name":"50 Landmark Papers","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116496432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-26DOI: 10.1201/9780429316944-34
C. Ball
{"title":"TG13: Updated Tokyo Guidelines for the Management of Acute Cholangitis and Cholecystitis","authors":"C. Ball","doi":"10.1201/9780429316944-34","DOIUrl":"https://doi.org/10.1201/9780429316944-34","url":null,"abstract":"","PeriodicalId":282445,"journal":{"name":"50 Landmark Papers","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121462795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-26DOI: 10.1201/9780429316944-88
A. Mehrotra, Natasha Keric
{"title":"Delirium as a Predictor of Mortality in Mechanically Ventilated Patients in the Intensive Care Unit","authors":"A. Mehrotra, Natasha Keric","doi":"10.1201/9780429316944-88","DOIUrl":"https://doi.org/10.1201/9780429316944-88","url":null,"abstract":"","PeriodicalId":282445,"journal":{"name":"50 Landmark Papers","volume":"68 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124840321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-11-26DOI: 10.1201/9780429316944-82
M. Shapiro
{"title":"Early versus Late Parenteral Nutrition in Critically Ill Adults","authors":"M. Shapiro","doi":"10.1201/9780429316944-82","DOIUrl":"https://doi.org/10.1201/9780429316944-82","url":null,"abstract":"","PeriodicalId":282445,"journal":{"name":"50 Landmark Papers","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117048519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-07-24DOI: 10.1201/9781315154053-34
Geoffrey P. Stricsek, J. Harrop
{"title":"Radiographic Analysis of Sagittal Plane Alignment and Balance in Standing Volunteers and Patients with Low Back Pain Matched for Age, Sex, and Size: A Prospective Controlled Clinical Study *","authors":"Geoffrey P. Stricsek, J. Harrop","doi":"10.1201/9781315154053-34","DOIUrl":"https://doi.org/10.1201/9781315154053-34","url":null,"abstract":"","PeriodicalId":282445,"journal":{"name":"50 Landmark Papers","volume":"114 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129930606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-07-24DOI: 10.1201/9781315154053-26
A. Shaw, D. Ikeda, H. Farhadi
{"title":"2001 Volvo Award Winner in Clinical Studies: Lumbar Fusion versus Nonsurgical Treatment for Chronic Low Back Pain: A Multicenter Randomized Controlled Trial from the Swedish Lumbar Spine Study Group *","authors":"A. Shaw, D. Ikeda, H. Farhadi","doi":"10.1201/9781315154053-26","DOIUrl":"https://doi.org/10.1201/9781315154053-26","url":null,"abstract":"","PeriodicalId":282445,"journal":{"name":"50 Landmark Papers","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115834472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-07-24DOI: 10.1201/9781315154053-11
B. Kundu, G. Hawryluk
{"title":"Methylprednisolone for Acute Spinal Cord Injury: An Inappropriate Standard of Care *","authors":"B. Kundu, G. Hawryluk","doi":"10.1201/9781315154053-11","DOIUrl":"https://doi.org/10.1201/9781315154053-11","url":null,"abstract":"","PeriodicalId":282445,"journal":{"name":"50 Landmark Papers","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128816788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-07-24DOI: 10.1201/9781315154053-13
R. Schouten
{"title":"Fractures of the Ring of the Axis: A Classification Based on the Analysis of 131 Cases *","authors":"R. Schouten","doi":"10.1201/9781315154053-13","DOIUrl":"https://doi.org/10.1201/9781315154053-13","url":null,"abstract":"","PeriodicalId":282445,"journal":{"name":"50 Landmark Papers","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121950537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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