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Leishmaniose Visceral no Brasil: o que é preciso saber 巴西内脏利什曼病:你需要知道的
Pub Date : 2021-05-27 DOI: 10.56242/globalhealth;2021;1;3;24-31
Roberta Carvalho de Freitas e Azevedo, Ryan Emiliano de Silva, Jaciara de Oliveira Jorge Costa, Isabela Pereira Pesenato, Sergio Paulo Josely Souza, Giovanna Stefani Nosberto Castelli, Caio Izidoro Campolongo, Camila de Abreu Aires Ribeiro Costa, Thiago Fakelmann, Joysse Wedja Soares Marques, Arlei Marcili
Species of the Leishmania genus parasitize mammals in the New World and have life cycles alternating between vertebrates and invertebrates. Visceral Leishmaniasis is an important zoonosis which has wild and domestic canids as important known reservoirs, and the genetic diversity of Leishmania (Leishmania) infantum in Brazil it is not yet known. Leishmaniasis is a serious disease with a wide geographical distribution and an incidence of two million cases per year. In the current study we address the main aspects of Visceral Leishmaniasis.
利什曼原虫属的物种寄生于新大陆的哺乳动物,其生命周期在脊椎动物和无脊椎动物之间交替。内脏利什曼病是一种重要的人畜共患病,野生和家养犬是已知的重要宿主,巴西利什曼原虫(利什曼原虫)幼崽的遗传多样性尚不清楚。利什曼病是一种严重的疾病,地理分布广泛,每年发病率为200万例。在目前的研究中,我们解决内脏利什曼病的主要方面。
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引用次数: 1
Avaliação do padrão respiratório pós extubação e indicação de condutas em UTI pediátrica 儿科icu拔管后呼吸模式评估及导管适应症
Pub Date : 2021-05-27 DOI: 10.56242/globalhealth;2021;1;3;40-44
Alessa Castro Ribeiro, Michele de Morais Rodrigues Sousa
OBJECTIVE: To employ the Wood-Downes Score and the upper airway obstruction score proposed by Downes and Raphaelly in the assessment of respiratory patterns and the indication of oxygen and ventilation support devices after orotracheal extubation. METHODS: It is a cross-sectional, descriptive, and quantitative study. The group was composed of 15 infants aged 28 days to 2 years old, hospitalized at the pediatric intensive care unit from august to october 2018, fulfilling the inclusion criteria and following the ethical in research aspects. RESULTS: Out of fifteen infants in the sample, 66,66% were female. The mean age was 6,4 ±6,27 months. The most common Wood-Downes score at baseline was moderate with mean 3,4 ±1,91, going to mild 1,6 ±0,89 at the second moment. The mean upper airway obstruction score at baseline was 2,9 ±1,62 decreasing to 1,7 ±0,79 at the second moment. ONCLUSION: The employment of the Wood-Downes Score and the upper airway obstruction score proposed by Downes and Raphaelly to assess the respiratory patterns in the present study, showed efficacy in the indication of non-invasive ventilatory support because the moderate score was the most present. Although the study did not interfere in the medical conduct, it is believed that the scores employed are useful tools to the control and assessment of the acute respiratory insufficiency after infant extubation.
目的:应用Downes和Raphaelly提出的Wood-Downes评分和上气道梗阻评分评价患者气管拔管后的呼吸方式及供氧和通气支持装置的适应证。方法:采用横断面、描述性和定量研究。本研究由2018年8月至10月在儿科重症监护病房住院的15名28天至2岁的婴儿组成,符合纳入标准,研究方面遵循伦理。结果:15例患儿中,66.66%为女婴。平均年龄(6.4±6.27)个月。最常见的Wood-Downes评分在基线时为中度,平均为3,4±1,91,第二时刻为轻度,为1,6±0,89。基线时平均上气道阻塞评分为2,9±1,62,第二时刻为1,7±0,79。结论:本研究采用Wood-Downes评分和Downes和Raphaelly提出的上气道阻塞评分来评估呼吸模式,由于中等评分最多,因此在无创通气支持指征方面效果较好。虽然本研究未干预医疗行为,但认为所采用的评分对于婴儿拔管后急性呼吸功能不全的控制和评估是有用的工具。
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引用次数: 0
Especialização em Saúde da Família UNA-SUS UNIFESP: dez anos de experiência em capacitação profissional UNIFESP家庭保健专业:十年专业培训经验
Pub Date : 2021-05-27 DOI: 10.56242/globalhealth;2021;1;3;67-72
Maria Elisabete Salvador, Rita Maria Lino Tarcia, Morris Pimenta de Souza, Daniel Almeida Gonçalves, Marco Antonio Manfredini, Silvio Carlos Coelho de Abreu, Marlene Sakumoto Akiyama, Felipe Vieira Pacheco, Daniel Lico dos Anjos Afonso dos Anjos Afonso, A. L. Pereira, Paulo Bandiera Paiva, Jorge Harada
OBJECTIVE: The purpose of the current study is to present the results of the implementation of innovations after ten years of analysis of professional training in the Specialization courses of the UNA-UHS Unifesp Program, as well as evaluations of the perceptions of students in relation to academic demands and professional practice. METHODS: This is a retrospective and descriptive observational study with a mixed approach, carried out in 2019 and 2020, in São Paulo. The methodological steps include a description of the technical-scientific evolution of the courses, considering pedagogical and technological aspects, and an analysis of 1,163 enrolled students (doctors working in Primary Care) using assessment instruments.The data are presented in absolute numbers and corresponding percentage frequencies. RESULTS: The modernization phase of the courses included technological innovations and updates of the pedagogical strategies for navigating content and activities. Regarding the analysis of the students, through responses categorized in a positive way for all the evaluated questions, it was possible to observe the delineation of the data that reflect the performance of tutors and the approximation of the contents/activities with professional practice. CONCLUSIONS: The pedagogical project, contents, technological infrastructure, educational resources, navigation routes, and course management have undergone relevant advances. These innovations expand the body of evidence in order to guarantee competences and skills, considering the academic and professional preferences of students. The courses of the UNA-UHS Unifesp Program contribute to the strengthening of the Unified Health System, by expanding the perspective of training in Family Health.
目的:本研究的目的是通过对UNA-UHS Unifesp专业课程专业培训的十年分析,以及对学生对学术需求和专业实践的看法的评估,展示创新实施的结果。方法:这是一项回顾性和描述性观察性研究,采用混合方法,于2019年和2020年在圣保罗州进行。方法步骤包括描述课程的技术-科学演变,考虑到教学和技术方面,并使用评估工具对1,163名注册学生(从事初级保健工作的医生)进行分析。数据以绝对数字和相应的百分比频率表示。结果:课程的现代化阶段包括技术创新和教学策略的更新,以导航内容和活动。关于学生的分析,通过对所有评估问题进行积极分类的回答,可以观察到反映导师表现的数据的描述以及与专业实践的内容/活动的近似。结论:教学项目、教学内容、技术基础设施、教学资源、导航路线、课程管理等方面均取得了相应进展。这些创新扩大了证据体系,以保证能力和技能,同时考虑到学生的学术和专业偏好。UNA-UHS uniifesp方案的课程通过扩大家庭保健培训的视角,有助于加强统一保健系统。
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引用次数: 0
Lurasidona no Manejo do Transtorno do Espectro Autista: Uma Revisão 鲁拉西酮在自闭症谱系障碍治疗中的应用综述
Pub Date : 2021-05-27 DOI: 10.56242/globalhealth;2021;1;3;16-18
Ricardo Vieira Nasser, B. Modesto, Arthur Lopes Ribeiro Penido, Sônia Maria Motta Palma
OBJECTIVE: To demonstrate that lurasidone can be an alternative for adolescents with Autistic Spectrum Disorder (ASD), especially if the patient has a history of adverse metabolic effects and / or ineffectiveness or intolerance to the use of aripiprazole or risperidone. METHODS: Systematic review of articles from the PubMed platform, with only articles in Portuguese and English being selected, with no period limitation. Inclusion criteria for the study: studies that address the treatment of ASD; studies that address treatment focusing on the use of lurasidone; works that bring clear methodology. RESULTS: Lurasidone has shown promise, given its low profile of adverse effects, such as lower weight gain, hyperlipidemia, hyperglycemia and insulin resistance. In addition to the potential benefits of lurasidone for the treatment of irritability in children with ASD, there may also be a potential antidepressant effect, which may influence the symptom profile. It is currently approved by the Food and Drug Administration (FDA) for the treatment of schizophrenia in adolescents from the age of thirteen and on monotherapy for bipolar depression from the age of ten. However, there are studies of tolerance in children and adolescents from the age of six with doses <120 mg / day. CONCLUSION: Given the risk of long-term adverse metabolic effects of most atypical antipsychotics, lurasidone can serve as an alternative. However, to date, no evidence has been found consistent with the use of lurasidone for patients with ASD who exhibit irritability, aggressiveness and impulsivity as associated symptoms.
目的:证明鲁拉西酮可以作为青少年自闭症谱系障碍(ASD)的替代药物,特别是如果患者有不良代谢反应和/或对阿立哌唑或利培酮无效或不耐受的病史。方法:系统回顾PubMed平台上的文章,只选择葡萄牙语和英语的文章,没有时间限制。本研究的纳入标准:涉及ASD治疗的研究;针对鲁拉西酮治疗的研究;带来清晰方法论的作品。结果:鲁拉西酮显示出前景,因为它的不良反应较低,如降低体重增加、高脂血症、高血糖和胰岛素抵抗。除了鲁拉西酮在治疗ASD患儿易怒方面的潜在益处外,它还可能具有潜在的抗抑郁作用,这可能会影响症状特征。它目前已被美国食品和药物管理局(FDA)批准用于治疗13岁以上青少年的精神分裂症和10岁以上双相抑郁症的单药治疗。然而,有研究表明6岁以上儿童和青少年对剂量<120毫克/天的耐受性。结论:考虑到大多数非典型抗精神病药物存在长期代谢不良的风险,鲁拉西酮可作为替代药物。然而,到目前为止,还没有证据表明鲁拉西酮适用于表现出易怒、攻击性和冲动相关症状的ASD患者。
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引用次数: 0
Adequação das boas práticas em dois restaurantes do tipo fast-food no município de São Paulo, SP, Brasil 在sao Paulo, SP,巴西的两家快餐店的良好做法的充分性
Pub Date : 2021-05-27 DOI: 10.56242/globalhealth;2021;1;3;19-23
Marcia Lopes Weber, Aline Milan, Joyce de Paula Silva, Natália Marques Nogueira, Pâmela Rodrigues Da Silva
OBJECTIVE: To identify the adequacy of good practices in two restaurants of two American fast-food franchises in the city of São Paulo, SP, Brazil. METHODS: A checklist adapted from the health legislation was used in each restaurant, identified as A and B, whose items were grouped into 5 blocks: Building and installation, Equipment, furniture and utensils, Handlers, Food production and transportation, and Documentation. The classification of the restaurants was based on the sanitary legislation: group 1, between 75 and 100% of conformities; group 2, between 51 and 74% of conformities; and group 3, from 0 to 50% of conformities. The general classification of the restaurants and by block of items was carried out. RESULTS:Restaurant A was classified in group 2 and B in group 1. Most of the non-conformities were observed in the blocks Documentation, Production and transport, and Manipulators for both restaurants; and Building and installation for restaurant A. CONCLUSION: Restaurant B had a higher percentage of conformities than restaurant A, and the classification was group 1 and 2, respectively. Regardless of the classification, both presented non-conformities relevant to the safety of the food produced. Based on that, it is suggested to apply an action plan to adapt to the current legislation, guaranteeing quality to food and health to consumers.
目的:确定在圣保罗市,SP,巴西的两个美国快餐特许经营的两个餐馆的良好做法的充分性。方法:在每个餐厅使用一份根据卫生法规改编的清单,确定为A和B,其项目分为5个部分:建筑和安装,设备,家具和器具,操作人员,食品生产和运输以及文件。根据卫生法规对餐厅进行分类:第一类,合格率在75%到100%之间;第2组,符合度在51 - 74%之间;第三组,从0到50%的符合度。对餐厅进行了总体分类,并按项目块进行了分类。结果:A餐厅归为第2组,B餐厅归为第1组。大部分不符合项是在两个餐厅的文件、生产和运输以及操作部门中发现的;结论:B餐厅的合格率高于a餐厅,分别属于第1类和第2类。无论分类如何,两者都提出了与所生产食品安全相关的不符合项。在此基础上,建议制定适应现行立法的行动计划,保障食品质量,保障消费者健康。
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引用次数: 0
Suporte ventilatório em UTI Pediátrica: estudo observacional 儿科icu的呼吸支持:观察性研究
Pub Date : 2021-05-27 DOI: 10.56242/globalhealth;2021;1;3;62-66
Alessa Castro Ribeiro, Renata Estevam Artagoitia
OBJECTIVE: To characterize the management of mechanical ventilation, ventilatory weaning and tracheal extubation in the Pediatric Intensive Care Centers (PICC) of the Hospital Geral do Grajaú. METHODS: Prospective observational study conducted at the Pediatric Intensive Care Center (PICC) of the Hospital Geral do Grajaú (HGG) for 9 months. RESULTS: Ninety patients who were under mechanical ventilation were included in the study. Of these, 40 were girls and 50 were boys. With a mean age of 5.52 months. Respiratory diseases were diagnosed with hospitalization in 84 patients (93.3%). In 100% of the cases, the Ventilatory Mode Controlled Pressure after tracheal intubation was used. Patients were submitted to MV on average for 6.6 days. In 89 patients (98.8%), the ERT with PSV was performed. Seventy-three patients (81.1%) used NIV after extubation with an average of 2 days of use. In 81 patients (90%) extubation was successful. CONCLUSION: The pediatric population hospitalized in pediatric intensive care units requiring the use of invasive mechanical ventilation is mostly male, less than 6 months old, with indication for hospitalization for respiratory disorders. The use of invasive ventilatory support was on average 6.6 days. Success of tracheal extubation in 90% of patients. We suggest greater accuracy regarding the descriptions of health professionals in electronic medical records.
目的:了解总医院Grajaú儿科重症监护中心(PICC)机械通气、呼吸机脱机和气管拔管的管理情况。方法:在总医院Grajaú (HGG)儿科重症监护中心(PICC)进行为期9个月的前瞻性观察研究。结果:90例机械通气患者纳入研究。其中,40名女孩和50名男孩。平均年龄5.52个月。住院诊断呼吸道疾病84例(93.3%)。所有病例均采用气管插管后通气模式控制压通气。患者接受MV治疗的平均时间为6.6天。89例(98.8%)患者行ERT合并PSV。73例患者(81.1%)拔管后使用NIV,平均使用时间为2天。81例(90%)拔管成功。结论:需要使用有创机械通气的儿科重症监护病房住院儿童以男性为主,年龄小于6个月,以呼吸系统疾病为住院指征。使用有创呼吸支持的平均时间为6.6天。90%的患者气管拔管成功。我们建议提高电子病历中卫生专业人员描述的准确性。
{"title":"Suporte ventilatório em UTI Pediátrica: estudo observacional","authors":"Alessa Castro Ribeiro, Renata Estevam Artagoitia","doi":"10.56242/globalhealth;2021;1;3;62-66","DOIUrl":"https://doi.org/10.56242/globalhealth;2021;1;3;62-66","url":null,"abstract":"OBJECTIVE: To characterize the management of mechanical ventilation, ventilatory weaning and tracheal extubation in the Pediatric Intensive Care Centers (PICC) of the Hospital Geral do Grajaú. METHODS: Prospective observational study conducted at the Pediatric Intensive Care Center (PICC) of the Hospital Geral do Grajaú (HGG) for 9 months. RESULTS: Ninety patients who were under mechanical ventilation were included in the study. Of these, 40 were girls and 50 were boys. With a mean age of 5.52 months. Respiratory diseases were diagnosed with hospitalization in 84 patients (93.3%). In 100% of the cases, the Ventilatory Mode Controlled Pressure after tracheal intubation was used. Patients were submitted to MV on average for 6.6 days. In 89 patients (98.8%), the ERT with PSV was performed. Seventy-three patients (81.1%) used NIV after extubation with an average of 2 days of use. In 81 patients (90%) extubation was successful. CONCLUSION: The pediatric population hospitalized in pediatric intensive care units requiring the use of invasive mechanical ventilation is mostly male, less than 6 months old, with indication for hospitalization for respiratory disorders. The use of invasive ventilatory support was on average 6.6 days. Success of tracheal extubation in 90% of patients. We suggest greater accuracy regarding the descriptions of health professionals in electronic medical records.","PeriodicalId":285800,"journal":{"name":"Brazilian Journal of Global Health","volume":"206 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116043125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Eficácia e segurança da Venlafaxina para prevenção de migrânea vestibular 文拉法辛预防前庭偏头痛的有效性和安全性
Pub Date : 2021-05-27 DOI: 10.56242/globalhealth;2021;1;3;57-61
Alana Asciutti Victorino, Fernando Veiga Angélico Júnior, Paula Ribeiro Lopes Almeida, Priscila Bogar, Osmar Clayton Person
OBJECTIVE: To evaluate the efficacy and safety of Venlafaxine for the control of vestibular migraine (VM). METHODS: This is a systematic review of randomized clinical trials. The following databases were searched: PUBMED (1966-2021), EMBASE (1974-2021) and CENTRAL (Cochrane Library-2021). There was no geographic and period limitation in the survey. Data extraction and study quality assessment were carried out by two independent researchers. RESULTS: The search strategy identified 47 studies, of which 2 were included in this review, as they met the inclusion and exclusion criteria. Both evaluated the efficacy of venlafaxine in vestibular migraine, comparing the results with other drugs. The first study (2017) compared the effect of venlafaxine with flunarizine and valproic acid, while the second study (2015) compared the efficacy of venlafaxine with propranolol. Both showed improvement of vestibular symptoms in all groups evaluated, but only the groups submitted to treatment with venlafaxine showed a significant change in the emotional DHI (Dizziness Handicap Inventory) score and improvement in depressive symptoms. CONCLUSIONS: Although venlafaxine appears to have promising results, there is currently a scarcity of studies that allow currently to assess the efficacy and safety of the drug for the treatment of vestibular migraine. The evidence is quite limited, the number of studies and patients evaluated reduced, and it is recommended to conduct new quality randomized clinical trials to elucidate the issue.
目的:评价文拉法辛治疗前庭偏头痛(VM)的疗效和安全性。方法:这是一项随机临床试验的系统综述。检索了以下数据库:PUBMED(1966-2021)、EMBASE(1974-2021)和CENTRAL (Cochrane Library-2021)。调查没有地域和时间限制。数据提取和研究质量评估由两名独立研究人员进行。结果:检索策略确定了47项研究,其中2项纳入本综述,因为它们符合纳入和排除标准。两项研究都评估了文拉法辛治疗前庭偏头痛的疗效,并将结果与其他药物进行了比较。第一项研究(2017年)比较了文拉法辛与氟桂利嗪和丙戊酸的疗效,第二项研究(2015年)比较了文拉法辛与心得安的疗效。所有评估组均显示前庭症状改善,但只有接受文拉法辛治疗的组在情绪DHI(头晕障碍量表)评分和抑郁症状改善方面表现出显著变化。结论:虽然文拉法辛似乎有很好的结果,但目前缺乏研究来评估该药物治疗前庭偏头痛的有效性和安全性。证据相当有限,研究和评估的患者数量减少,建议进行新的高质量随机临床试验来阐明这一问题。
{"title":"Eficácia e segurança da Venlafaxina para prevenção de migrânea vestibular","authors":"Alana Asciutti Victorino, Fernando Veiga Angélico Júnior, Paula Ribeiro Lopes Almeida, Priscila Bogar, Osmar Clayton Person","doi":"10.56242/globalhealth;2021;1;3;57-61","DOIUrl":"https://doi.org/10.56242/globalhealth;2021;1;3;57-61","url":null,"abstract":"OBJECTIVE: To evaluate the efficacy and safety of Venlafaxine for the control of vestibular migraine (VM). METHODS: This is a systematic review of randomized clinical trials. The following databases were searched: PUBMED (1966-2021), EMBASE (1974-2021) and CENTRAL (Cochrane Library-2021). There was no geographic and period limitation in the survey. Data extraction and study quality assessment were carried out by two independent researchers. RESULTS: The search strategy identified 47 studies, of which 2 were included in this review, as they met the inclusion and exclusion criteria. Both evaluated the efficacy of venlafaxine in vestibular migraine, comparing the results with other drugs. The first study (2017) compared the effect of venlafaxine with flunarizine and valproic acid, while the second study (2015) compared the efficacy of venlafaxine with propranolol. Both showed improvement of vestibular symptoms in all groups evaluated, but only the groups submitted to treatment with venlafaxine showed a significant change in the emotional DHI (Dizziness Handicap Inventory) score and improvement in depressive symptoms. CONCLUSIONS: Although venlafaxine appears to have promising results, there is currently a scarcity of studies that allow currently to assess the efficacy and safety of the drug for the treatment of vestibular migraine. The evidence is quite limited, the number of studies and patients evaluated reduced, and it is recommended to conduct new quality randomized clinical trials to elucidate the issue.","PeriodicalId":285800,"journal":{"name":"Brazilian Journal of Global Health","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129387028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oral conditions in HIV patients HIV患者的口腔状况
Pub Date : 2021-05-27 DOI: 10.56242/globalhealth;2021;1;3;53-56
Caio Vinicius Gonçalves Roman-Torres, Camila Barreto Barbieri, Luciano Martins, F. Pasquinelli, Marcelo Melo Quintela
OBJECTIVE: It is estimated that almost 38 million people are currently living with HIV, with more than a third presenting oral manifestations. The high degree of immunological weakness of these patients has a huge impact on their quality of life and can be seen clinically in the oral cavity. METHODS: The present study sought to evaluate the oral manifestations most due to HIV infection. This study had as methodology, the active search for information in the databases of the Medline, Lilacs, SciELO, Embase and Cochrane. It was sought to carry out the bibliographic research on the two central themes of this work: buccal manifestations and hiv, mouth care in hiv patients, oral care hiv, oral health in hiv, Aids oral care, Aids oral manifestations, mouth care in Aids patients. RESULTS: It was observed at least 24 different oral lesions reported in the HIV literature, but only ten of them are found consistently, and these, in decreasing prevalence, are oral candidiasis, oral hairy leukoplakia, herpes simplex virus infection. Oral candidiasis was reported as the most commonly found in different countries, including studies in groups that performed antiretroviral therapy. Such lesions may be of bacterial, viral, fungal origin, neoplastic processes and lesions of unknown etiology, as well as periodontal manifestations, which may be aggravated. CONCLSUION: Antiretroviral therapy improves immune competence by attacking HIV viral replication and its immediate start is now recommended for all HIV-infected adults, adolescents and children with oropharyngeal candidiasis according to the guidelines of the World Health Organization.
目的:据估计,目前有近3800万人感染艾滋病毒,其中超过三分之一的人有口腔表现。这些患者的免疫功能高度衰弱,对其生活质量影响巨大,临床上可在口腔中看到。方法:本研究旨在评估HIV感染引起的口腔表现。本研究的方法是在Medline、Lilacs、SciELO、Embase和Cochrane等数据库中积极检索信息。试图对这项工作的两个中心主题进行书目研究:口腔表现与艾滋病毒,艾滋病毒患者的口腔护理,艾滋病毒口腔护理,艾滋病毒口腔健康,艾滋病口腔护理,艾滋病口腔表现,艾滋病患者的口腔护理。结果:在HIV文献中观察到至少24种不同的口腔病变,但其中只有10种是一致的,这些是口腔念珠菌病,口腔毛状白斑,单纯疱疹病毒感染,患病率呈下降趋势。据报道,口腔念珠菌病在不同国家最常见,包括在接受抗逆转录病毒治疗的群体中进行的研究。这些病变可能是细菌、病毒、真菌、肿瘤过程和病因不明的病变,以及可能加重的牙周表现。结论:抗逆转录病毒治疗通过攻击HIV病毒复制来提高免疫能力,根据世界卫生组织的指南,现在建议所有感染HIV的成人、青少年和患有口咽念珠菌病的儿童立即开始抗逆转录病毒治疗。
{"title":"Oral conditions in HIV patients","authors":"Caio Vinicius Gonçalves Roman-Torres, Camila Barreto Barbieri, Luciano Martins, F. Pasquinelli, Marcelo Melo Quintela","doi":"10.56242/globalhealth;2021;1;3;53-56","DOIUrl":"https://doi.org/10.56242/globalhealth;2021;1;3;53-56","url":null,"abstract":"OBJECTIVE: It is estimated that almost 38 million people are currently living with HIV, with more than a third presenting oral manifestations. The high degree of immunological weakness of these patients has a huge impact on their quality of life and can be seen clinically in the oral cavity. METHODS: The present study sought to evaluate the oral manifestations most due to HIV infection. This study had as methodology, the active search for information in the databases of the Medline, Lilacs, SciELO, Embase and Cochrane. It was sought to carry out the bibliographic research on the two central themes of this work: buccal manifestations and hiv, mouth care in hiv patients, oral care hiv, oral health in hiv, Aids oral care, Aids oral manifestations, mouth care in Aids patients. RESULTS: It was observed at least 24 different oral lesions reported in the HIV literature, but only ten of them are found consistently, and these, in decreasing prevalence, are oral candidiasis, oral hairy leukoplakia, herpes simplex virus infection. Oral candidiasis was reported as the most commonly found in different countries, including studies in groups that performed antiretroviral therapy. Such lesions may be of bacterial, viral, fungal origin, neoplastic processes and lesions of unknown etiology, as well as periodontal manifestations, which may be aggravated. CONCLSUION: Antiretroviral therapy improves immune competence by attacking HIV viral replication and its immediate start is now recommended for all HIV-infected adults, adolescents and children with oropharyngeal candidiasis according to the guidelines of the World Health Organization.","PeriodicalId":285800,"journal":{"name":"Brazilian Journal of Global Health","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131739470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnóstico molecular para hemoparasitos em cães atendidos no Hospital Veterinário da Universidade Santo Amaro, São Paulo, SP, Brasil 在圣阿马洛大学兽医医院治疗的狗血液寄生虫的分子诊断,sao保罗,SP,巴西
Pub Date : 2021-05-27 DOI: 10.56242/globalhealth;2021;1;3;7-11
E. Silva Júnior, Adriana Cortez, Renata Bottura, Simone Gonçalves Rodrigues Gomes, Rafael Garabet Agopian, Jonas Moraes Filho
OBJECTIVE: Detection of Ehrlichia canis, Rickettsia rickettsii, Anaplasma platys, Rangelia vitalii, and Babesia canis vogeli using real-time PCR in dogs treated at the veterinary hospital of the Universidade Santo Amaro, located in the south zone, in the city of São Paulo, SP, Brazil. METHODS: DNA was extracted from 63 whole blood samples using the “PureLink Genomic DNA” extraction kit (Invitrogen®) according to the manufacturer's instructions and real-time PCR was performed to detect Ehrlichia canis, Rickettsia rickettsii, Anaplasma platys, Rangelia vitalii, and Babesia canis vogeli. RESULTS: In total, 23.8% (15/63) of the samples were positive by real-time PCR for at least one pathogen. Of these, 9.52% (6/63) were positive for Babesia canis vogeli and 14.2% (9/63) for Ehrlichia canis. No samples were positive for Rickettsia rickettsii, Rangelia vitalii, and Anaplasma platys. CONCLUSION: This study demonstrated, in an unprecedented way, the presence of B. canis vogeli and E. canis in dogs from fragmentation areas of the Atlantic Forest around the Guarapiranga Reservoir in the city of São Paulo, expanding knowledge on the dispersion of this agent in Brazil.
目的:利用实时荧光定量PCR技术检测巴西圣保罗市圣阿马洛大学兽医院收治犬的犬埃利希体、立克次体、platys无形体、vitalirangelia vogeli犬巴贝斯虫。方法:采用“PureLink Genomic DNA”提取试剂盒(Invitrogen®)按照说明书提取63份全血样本的DNA,实时荧光定量PCR检测犬埃利希体、立克次体、platys无原体、Rangelia vitalii和犬巴贝斯虫vogeli。结果:23.8%(15/63)的标本实时荧光定量PCR检测至少一种病原菌。其中犬巴贝斯虫阳性9.52%(6/63),犬埃利希体阳性14.2%(9/63)。未发现立克次体、重要兰氏菌和扁平无原体阳性样本。结论:本研究以前所未有的方式证明,在圣保罗市瓜拉皮兰加水库周围大西洋森林破碎区的狗中存在犬B. vogeli和犬E. canis,扩大了对该剂在巴西扩散的认识。
{"title":"Diagnóstico molecular para hemoparasitos em cães atendidos no Hospital Veterinário da Universidade Santo Amaro, São Paulo, SP, Brasil","authors":"E. Silva Júnior, Adriana Cortez, Renata Bottura, Simone Gonçalves Rodrigues Gomes, Rafael Garabet Agopian, Jonas Moraes Filho","doi":"10.56242/globalhealth;2021;1;3;7-11","DOIUrl":"https://doi.org/10.56242/globalhealth;2021;1;3;7-11","url":null,"abstract":"OBJECTIVE: Detection of Ehrlichia canis, Rickettsia rickettsii, Anaplasma platys, Rangelia vitalii, and Babesia canis vogeli using real-time PCR in dogs treated at the veterinary hospital of the Universidade Santo Amaro, located in the south zone, in the city of São Paulo, SP, Brazil. METHODS: DNA was extracted from 63 whole blood samples using the “PureLink Genomic DNA” extraction kit (Invitrogen®) according to the manufacturer's instructions and real-time PCR was performed to detect Ehrlichia canis, Rickettsia rickettsii, Anaplasma platys, Rangelia vitalii, and Babesia canis vogeli. RESULTS: In total, 23.8% (15/63) of the samples were positive by real-time PCR for at least one pathogen. Of these, 9.52% (6/63) were positive for Babesia canis vogeli and 14.2% (9/63) for Ehrlichia canis. No samples were positive for Rickettsia rickettsii, Rangelia vitalii, and Anaplasma platys. CONCLUSION: This study demonstrated, in an unprecedented way, the presence of B. canis vogeli and E. canis in dogs from fragmentation areas of the Atlantic Forest around the Guarapiranga Reservoir in the city of São Paulo, expanding knowledge on the dispersion of this agent in Brazil.","PeriodicalId":285800,"journal":{"name":"Brazilian Journal of Global Health","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129990363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Decrease in search to hospitals and health services and the interruption of therapeutics and treatments during pandemic 在大流行期间,到医院和卫生服务机构就诊的人数减少,治疗和治疗中断
Pub Date : 2021-05-27 DOI: 10.56242/globalhealth;2021;1;3;35-39
Gabriela Marinho Garcia de Barros, Gabriella de Souza Louver, Giulia Valentin Barros, Layla Cristina Barros Teixeira, Larissa Alves Christensem Pereira, Melissa Mautoni Marcondes Machado, Natália de Barros Marinho, Leonardo Sokolnik de Oliveira
OBJECTIVE: The objective of this study was to evaluate the impact of the COVID-19 pandemic over the search for healthcare services according to four criteria (cancellation of medical consultations, suspension of treatments, postponement of surgeries and non-performance of routine tests), comparing the results between genders and age groups. METHODS: A survey was conducted through an internet questionnaire in October 2020. RESULTS: 602 responses were obtained, and the results were that women had lower rates of going to health services compared to men and individuals belonging to the elderly age group canceled more medical visits, interrupted more therapies, and postponed more surgeries than other age groups. CONCLUSION: Considering the overview of all age groups, the pandemic caused a decrease of about 28% in the demand for medical consultations and this decrease is more significant among the elderly and women. These results emphasize the need for specific campaigns for these people in periods of social isolation due to the pandemics.
目的:本研究的目的是评估COVID-19大流行对寻求医疗服务的四个标准(取消就诊、暂停治疗、推迟手术和未进行常规检查)的影响,并比较性别和年龄组之间的结果。方法:于2020年10月通过网络问卷进行调查。结果:共获得602份回复,结果表明,女性去医疗服务的比例低于男性,老年群体比其他年龄组更多地取消了就诊,中断了更多的治疗,推迟了更多的手术。结论:考虑到所有年龄组的总体情况,大流行导致医疗咨询需求下降约28%,其中老年人和妇女的下降更为明显。这些结果强调,在流行病造成的社会孤立时期,有必要为这些人开展具体的运动。
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引用次数: 0
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